Association between tuberculosis and a polymorphic NFκB binding site in the interferon γ gene

Lancet

Volumn 361, Issue 9372, 2003, Pages 1871-1872

  Rossouw, Manda ^a   Nel, Hendrik J ^a   Cooke, Graham S ^b   Van Helden, Paul D ^a   Hoal, Eileen G ^a  

^a STELLENBOSCH UNIVERSITY   (South Africa)

^b UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; GAMMA INTERFERON; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; TRANSCRIPTION FACTOR;

ALLELE; ARTICLE; BINDING AFFINITY; BINDING SITE; CASE CONTROL STUDY; CONTROLLED STUDY; DISEASE COURSE; DNA POLYMORPHISM; FAMILY STUDY; GENE EXPRESSION; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; HUMAN; INFECTION SENSITIVITY; MAJOR CLINICAL STUDY; POPULATION RESEARCH; PRIORITY JOURNAL; SOUTH AFRICA; TUBERCULOSIS;

EID: 0038054446     PISSN: 01406736     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0140-6736(03)13491-5     Document Type: Article

References (5)

1. Flynn J.L., Chan J. Immunology of tuberculosis. Annu Rev Immunol. 19:2001;93-129.
2. Bream J.H., Carrington M., O'Toole S., et al. Polymorphisms of the human IFNG gene noncoding regions. Immunogenetics. 51:2000;50-58.
3. Pravica V., Perrey C., Stevens A., Lee J.H., Hutchinson I.V. A single nucleotide polymorphism in the first intron of the human IFN-gamma gene: absolute correlation with a polymorphic CA microsatellite marker of high IFN-gamma production. Hum Immunol. 61:2000;863-866.
4. Hoal-van Helden E.G., Epstein J., Victor T.C., et al. Mannose-binding protein B allele confers protection against tuberculous meningitis. Pediatr Res. 45:1999;459-464.
5. Yamada H., Mizuno S., Reza-Gholizadeh M., Sugawara I. Relative importance of NF-kappaB p50 in mycobacterial infection. Infect Immun. 69:2001;7100-7105.