Rational development of a serum-free medium and fed-batch process for a GS-CHO cell line expressing recombinant antibody

Cytotechnology

Volumn 65, Issue 3, 2013, Pages 363-378

  Zhang, Huifeng ^a   Wang, Haibin ^b   Liu, Mei ^a   Zhang, Tao ^a   Zhang, Ji ^a   Wang, Xiangjing ^a   Xiang, Wensheng ^a  

^a NORTHEAST AGRICULTURAL UNIVERSITY   (China)

^b Zhejiang Hisun Pharmaceutical Co Ltd   (China)

Author keywords

Design of experiment (DoE); Fed batch process; GS CHO cell; Recombinant antibody; SFM

Indexed keywords

AMINO ACID; INSULIN; POLOXAMER; RECOMBINANT ANTIBODY; TRANSFERRIN;

ANIMAL CELL; ANTIBODY PRODUCTION; ANTIBODY TITER; ARTICLE; CELL GROWTH; CELL LINE; CULTURE MEDIUM; FED BATCH CULTURE; NONHUMAN;

EID: 84876491458     PISSN: 09209069     EISSN: 15730778     Source Type: Journal    
DOI: 10.1007/s10616-012-9488-4     Document Type: Article

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