-
1
-
-
0030597114
-
Molecular cloning of cDNA for nonhepatic mitochondrial arginase (argjnase II) and comparison of its induction with nitric oxide synthase in a murine macrophage-like cell line
-
Goth, T.S.T., Nagasaki, A., Terada, K., Takiguchi, M. & Mori, M. (1996) Molecular cloning of cDNA for nonhepatic mitochondrial arginase (argjnase II) and comparison of its induction with nitric oxide synthase in a murine macrophage-like cell line. FEBS Lett. 395, 119-122.
-
(1996)
FEBS Lett.
, vol.395
, pp. 119-122
-
-
Goth, T.S.T.1
Nagasaki, A.2
Terada, K.3
Takiguchi, M.4
Mori, M.5
-
3
-
-
0017623867
-
Oxidation of spermidine and spermine in rat liver: Purification and properties of polyamine oxidase
-
Hölttä, E. (1977) Oxidation of spermidine and spermine in rat liver: purification and properties of polyamine oxidase. Biochemistry 16, 91-100.
-
(1977)
Biochemistry
, vol.16
, pp. 91-100
-
-
Hölttä, E.1
-
4
-
-
0027238083
-
1-acetyltransferase - The turning point in polyamine metabolism
-
1-acetyltransferase - the turning point in polyamine metabolism. FASEB J. 7, 653-661.
-
(1993)
FASEB J.
, vol.7
, pp. 653-661
-
-
Casero, R.A.1
Pegg, A.E.2
-
5
-
-
0034623954
-
1-acetyltransferase on polyamine pool dynamics, cell growth, and sensitivity to polyamine analogs
-
1-acetyltransferase on polyamine pool dynamics, cell growth, and sensitivity to polyamine analogs. J. Biol. Chem. 275, 38319-38328.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 38319-38328
-
-
Vujcic, S.1
Halmekytö, M.2
Diegelman, P.3
Gan, G.4
Kramer, D.L.5
Jänne, J.6
Porter, C.W.7
-
6
-
-
0037067683
-
1- acetyltransferase gene in mouse embryonic stem cells. Effects on polyamine homeostasis and sensitivity to polyamine analogues
-
1-acetyltransferase gene in mouse embryonic stem cells. Effects on polyamine homeostasis and sensitivity to polyamine analogues. J. Biol. Chem. 277, 25323-25328.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 25323-25328
-
-
Niiranen, K.1
Pietilä, M.2
Pirttilä, T.J.3
Järvinen, A.4
Halmekytö, M.5
Korhonen, V.P.6
Keinänen, T.A.7
Alhonen, L.8
Jänne, J.9
-
7
-
-
0035878846
-
Cloning and characterization of a human polyamine oxidase that is inducible by polyamine analogue exposure
-
Wang, Y., Devereux, W., Woster, P.M., Stewart, T.M., Hacker, A. & Casero, R.A. Jr (2001) Cloning and characterization of a human polyamine oxidase that is inducible by polyamine analogue exposure. Cancer Res. 61, 5370-5373.
-
(2001)
Cancer Res.
, vol.61
, pp. 5370-5373
-
-
Wang, Y.1
Devereux, W.2
Woster, P.M.3
Stewart, T.M.4
Hacker, A.5
Casero Jr., R.A.6
-
8
-
-
0036846756
-
Identification and characterization of a novel flavin-containing spermine oxidase of mammalian cell origin
-
Vujcic, S., Diegelman, P., Bacchi, C.J., Kramer, D.L. & Porter, C.W. (2002) Identification and characterization of a novel flavin-containing spermine oxidase of mammalian cell origin. Biochem. J. 367, 665-675.
-
(2002)
Biochem. J.
, vol.367
, pp. 665-675
-
-
Vujcic, S.1
Diegelman, P.2
Bacchi, C.J.3
Kramer, D.L.4
Porter, C.W.5
-
9
-
-
0037449190
-
Properties of purified recombinant human polyamine oxidase, PAOh1/SMO
-
Wang, Y., Murray-Stewart, T., Devereux, W., Hacker, A., Frydman, B., Woster, P.M. & Casero, R.A. Jr (2003) Properties of purified recombinant human polyamine oxidase, PAOh1/SMO. Biochem. Biophys. Res. Commun. 304, 605-611.
-
(2003)
Biochem. Biophys. Res. Commun.
, vol.304
, pp. 605-611
-
-
Wang, Y.1
Murray-Stewart, T.2
Devereux, W.3
Hacker, A.4
Frydman, B.5
Woster, P.M.6
Casero Jr., R.A.7
-
10
-
-
0019570951
-
Identification of hypusine, an unusual amino acid, in protein from human lymphocytes and of spermidine as its biosynthetic precursor
-
Park, M.H., Cooper, H.L. & Folk, J.E. (1981) Identification of hypusine, an unusual amino acid, in protein from human lymphocytes and of spermidine as its biosynthetic precursor. Proc. Natl Acad. Sci. USA 78, 2869-2873.
-
(1981)
Proc. Natl Acad. Sci. USA
, vol.78
, pp. 2869-2873
-
-
Park, M.H.1
Cooper, H.L.2
Folk, J.E.3
-
11
-
-
0027370986
-
Is hypusine essential for eukaryotic cell proliferation?
-
Park, M.H., Wolff, E.C. & Folk, J.E. (1993) Is hypusine essential for eukaryotic cell proliferation? Trends Biochem. Sci. 18, 475-479.
-
(1993)
Trends Biochem. Sci.
, vol.18
, pp. 475-479
-
-
Park, M.H.1
Wolff, E.C.2
Folk, J.E.3
-
12
-
-
0017283631
-
The appearance of an ornithine decarboxylase inhibitory protein upon the addition of putrescine to cell cultures
-
Fong, W.F., Heller, J.S. & Canellakis, E.S. (1976) The appearance of an ornithine decarboxylase inhibitory protein upon the addition of putrescine to cell cultures. Biochim. Biophys. Acta 428, 456-465.
-
(1976)
Biochim. Biophys. Acta
, vol.428
, pp. 456-465
-
-
Fong, W.F.1
Heller, J.S.2
Canellakis, E.S.3
-
13
-
-
0345955882
-
Induction of a protein inhibitor to ornithine decarboxylase by the end products of its reaction
-
Heller, J.S., Fong, W.F. & Canellakis, E.S. (1976) Induction of a protein inhibitor to ornithine decarboxylase by the end products of its reaction. Proc. Natl Acad. Sci. USA 73, 1858-1862.
-
(1976)
Proc. Natl Acad. Sci. USA
, vol.73
, pp. 1858-1862
-
-
Heller, J.S.1
Fong, W.F.2
Canellakis, E.S.3
-
14
-
-
0017389042
-
Regulation of ornithine decarboxylase by ODC-antizyme in HTC cells. Biochem
-
McCann, P.P., Tardif, C. & Mamont, P.S. (1977) Regulation of ornithine decarboxylase by ODC-antizyme in HTC cells. Biochem. Biophys. Res. Commun. 75, 948-954.
-
(1977)
Biophys. Res. Commun.
, vol.75
, pp. 948-954
-
-
McCann, P.P.1
Tardif, C.2
Mamont, P.S.3
-
15
-
-
0030052923
-
Ornithine decarboxylase antizyme: A novel type of regulatory protein
-
Hayashi, S., Murakami, Y. & Matsufuji, S. (1996) Ornithine decarboxylase antizyme: a novel type of regulatory protein. Trends Biochem. Sci. 21, 27-30.
-
(1996)
Trends Biochem. Sci.
, vol.21
, pp. 27-30
-
-
Hayashi, S.1
Murakami, Y.2
Matsufuji, S.3
-
16
-
-
0035067587
-
Antizyme, a mediator of ubiquitin-independent proteasomal degradation
-
Coffino, P. (2001) Antizyme, a mediator of ubiquitin-independent proteasomal degradation. Biochimie 83, 319-323.
-
(2001)
Biochimie
, vol.83
, pp. 319-323
-
-
Coffino, P.1
-
17
-
-
0028296140
-
Feedback repression of polyamine transport is mediated by antizyme in mammalian tissue-culture cells
-
Mitchell, J.L.A., Judd, G.G., Bareyal-Leyser, A. & Ling, S.Y. (1994) Feedback repression of polyamine transport is mediated by antizyme in mammalian tissue-culture cells. Biochem. J. 299, 19-22.
-
(1994)
Biochem. J.
, vol.299
, pp. 19-22
-
-
Mitchell, J.L.A.1
Judd, G.G.2
Bareyal-Leyser, A.3
Ling, S.Y.4
-
18
-
-
0028831608
-
Autoregulatory frameshifting in decoding mammalian ornithine decarboxylase antizyme
-
Matsufuji, S., Matsufuji, T., Miyazaki, Y., Murakami, Y., Atkins, J.F., Gesteland, R.F. & Hayashi, S.-I. (1995) Autoregulatory frameshifting in decoding mammalian ornithine decarboxylase antizyme. Cell 80, 51-60.
-
(1995)
Cell
, vol.80
, pp. 51-60
-
-
Matsufuji, S.1
Matsufuji, T.2
Miyazaki, Y.3
Murakami, Y.4
Atkins, J.F.5
Gesteland, R.F.6
Hayashi, S.-I.7
-
19
-
-
23444435083
-
Polyamines regulate the expression of ornithine decarboxylase antizyme in vitro by inducing ribosomal frame-shifting
-
Rom, E. & Kahana, C. (1994) Polyamines regulate the expression of ornithine decarboxylase antizyme in vitro by inducing ribosomal frame-shifting. Proc. Natl Acad. Sci. USA 91, 3959-3963.
-
(1994)
Proc. Natl Acad. Sci. USA
, vol.91
, pp. 3959-3963
-
-
Rom, E.1
Kahana, C.2
-
20
-
-
0035108971
-
Nuclear translocation of antizyme and expression of ornithine decarboxylase and antizyme are developmentally regulated
-
Gritli-Linde, A., Nilsson, J., Bohlooly, Y.M., Heby, O. & Linde, A. (2001) Nuclear translocation of antizyme and expression of ornithine decarboxylase and antizyme are developmentally regulated. Dev. Dyn. 220, 259-275.
-
(2001)
Dev. Dyn.
, vol.220
, pp. 259-275
-
-
Gritli-Linde, A.1
Nilsson, J.2
Bohlooly, Y.M.3
Heby, O.4
Linde, A.5
-
21
-
-
0242666128
-
Identification of nuclear export signals in antizyme-1
-
Murai, N., Murakami, Y. & Matsufuji, S. (2003) Identification of nuclear export signals in antizyme-1. J. Biol. Chem. 278, 44791-44798.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 44791-44798
-
-
Murai, N.1
Murakami, Y.2
Matsufuji, S.3
-
22
-
-
0035824568
-
Proteasomal degradation of Smad1 induced by bone morphogenetic proteins
-
Gruendler, C., Lin, Y., Farley, J. & Wang, T. (2001) Proteasomal degradation of Smad1 induced by bone morphogenetic proteins. J. Biol. Chem. 276, 46533-46543.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 46533-46543
-
-
Gruendler, C.1
Lin, Y.2
Farley, J.3
Wang, T.4
-
23
-
-
2342666616
-
A novel link between the proteasome pathway and the signal transduction pathway of the bone morphogenetic proteins (BMPs)
-
Lin, Y., Martin, J., Gruendler, C., Farley, J., Meng, X., Li, B.Y., Lechleider, R., Huff, C., Kim, R.H., Grasser, W.A., Paralkar, V. & Wang, T. (2002) A novel link between the proteasome pathway and the signal transduction pathway of the bone morphogenetic proteins (BMPs). BMC Cell Biol. 3, 15.
-
(2002)
BMC Cell Biol.
, vol.3
, pp. 15
-
-
Lin, Y.1
Martin, J.2
Gruendler, C.3
Farley, J.4
Meng, X.5
Li, B.Y.6
Lechleider, R.7
Huff, C.8
Kim, R.H.9
Grasser, W.A.10
Paralkar, V.11
Wang, T.12
-
24
-
-
0345688128
-
A perspective of polyamine metabolism
-
Wallace, H.M., Fraser, A.V. & Hughes, A. (2003) A perspective of polyamine metabolism. Biochem. J. 376, 1-14.
-
(2003)
Biochem. J.
, vol.376
, pp. 1-14
-
-
Wallace, H.M.1
Fraser, A.V.2
Hughes, A.3
-
25
-
-
0141761500
-
Thirty years of polyamine-related approaches to cancer therapy. Retrospect and prospect. Part 2. Structural analogues and derivatives
-
Seiler, N. (2003) Thirty years of polyamine-related approaches to cancer therapy. Retrospect and prospect. Part 2. Structural analogues and derivatives. Curr. Drug Targets 4, 565-585.
-
(2003)
Curr. Drug Targets
, vol.4
, pp. 565-585
-
-
Seiler, N.1
-
26
-
-
0141633535
-
Thirty years of polyamine-related approaches to cancer therapy. Retrospect and prospect. Part 1. Selective enzyme inhibitors
-
Seiler, N. (2003) Thirty years of polyamine-related approaches to cancer therapy. Retrospect and prospect. Part 1. Selective enzyme inhibitors. Curr. Drug Targets 4, 537-564.
-
(2003)
Curr. Drug Targets
, vol.4
, pp. 537-564
-
-
Seiler, N.1
-
27
-
-
0025873423
-
Polyamines: From molecular biology to clinical applications
-
Jänne, J., Alhonen, L. & Leinonen, P. (1991) Polyamines: from molecular biology to clinical applications. Ann. Med. 23, 241-259.
-
(1991)
Ann. Med.
, vol.23
, pp. 241-259
-
-
Jänne, J.1
Alhonen, L.2
Leinonen, P.3
-
28
-
-
0037397642
-
Transgenic mouse models for studies of the role of polyamines in normal, hypertrophic and neoplastic growth
-
Pegg, A.E., Feith, D.J., Fong, L.Y., Coleman, C.S., O'Brien, T.G. & Shantz, L.M. (2003) Transgenic mouse models for studies of the role of polyamines in normal, hypertrophic and neoplastic growth. Biochem. Soc. Trans. 31, 356-360.
-
(2003)
Biochem. Soc. Trans.
, vol.31
, pp. 356-360
-
-
Pegg, A.E.1
Feith, D.J.2
Fong, L.Y.3
Coleman, C.S.4
O'Brien, T.G.5
Shantz, L.M.6
-
29
-
-
0025934534
-
Transgenic mice aberrantly expressing human ornithine decarboxylase gene
-
Halmekytö, M., Hyttinen, J.-M., Sinervirta, R., Utriainen, M., Myöhänen, S., Voipio, H.-M., Wahlfors, J., Syrjänen, S., Syrjänen, K., Alhonen, L. & Jänne, J. (1991) Transgenic mice aberrantly expressing human ornithine decarboxylase gene. J. Biol. Chem. 266, 19746-19751.
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 19746-19751
-
-
Halmekytö, M.1
Hyttinen, J.-M.2
Sinervirta, R.3
Utriainen, M.4
Myöhänen, S.5
Voipio, H.-M.6
Wahlfors, J.7
Syrjänen, S.8
Syrjänen, K.9
Alhonen, L.10
Jänne, J.11
-
30
-
-
0025934068
-
Position-independent, aberrant expression of the human ornithine decarboxylase gene in transgenic mice
-
Halmekytö, M., Alhonen, L., Wahlfors, J., Sinervirta, R., Jänne, O.A. & Jänne, J. (1991) Position-independent, aberrant expression of the human ornithine decarboxylase gene in transgenic mice. Biochem. Biophys. Res. Commun. 180, 262-267.
-
(1991)
Biochem. Biophys. Res. Commun.
, vol.180
, pp. 262-267
-
-
Halmekytö, M.1
Alhonen, L.2
Wahlfors, J.3
Sinervirta, R.4
Jänne, O.A.5
Jänne, J.6
-
31
-
-
0025772499
-
Characterization of a transgenic mouse line over-expressing the human ornithine decarboxylase gene
-
Halmekytö, M., Alhonen, L., Wahlfors, J., Sinervirta, R., Eloranta, T. & Jänne, J. (1991) Characterization of a transgenic mouse line over-expressing the human ornithine decarboxylase gene. Biochem. J. 278, 895-898.
-
(1991)
Biochem. J.
, vol.278
, pp. 895-898
-
-
Halmekytö, M.1
Alhonen, L.2
Wahlfors, J.3
Sinervirta, R.4
Eloranta, T.5
Jänne, J.6
-
32
-
-
0027172897
-
Transgenic mice over-producing putrescine in their tissues do not convert the diamine into higher polyamines
-
Halmekytö, M., Alhonen, L., Alakuijala, L. & Jänne, J. (1993) Transgenic mice over-producing putrescine in their tissues do not convert the diamine into higher polyamines. Biochem. J. 291, 505-508.
-
(1993)
Biochem. J.
, vol.291
, pp. 505-508
-
-
Halmekytö, M.1
Alhonen, L.2
Alakuijala, L.3
Jänne, J.4
-
33
-
-
0026695481
-
Sequestered end products and enzyme regulation: The case of ornithine decarboxylase
-
Davis, R.H., Morris, D.R. & Coffino, P. (1992) Sequestered end products and enzyme regulation: The case of ornithine decarboxylase. Microbiol. Rev. 56, 280-290.
-
(1992)
Microbiol. Rev.
, vol.56
, pp. 280-290
-
-
Davis, R.H.1
Morris, D.R.2
Coffino, P.3
-
34
-
-
0027504245
-
Polyamines and regulation of spermatogenesis: Selective stimulation of late spermatogonia in transgenic mice overexpressing the human ornithine decarboxylase gene
-
Hakovirta, H., Keiski, A., Toppari, J., Halmekytö, M., Alhonen, L., Jänne, J. & Parvinen, M. (1993) Polyamines and regulation of spermatogenesis: selective stimulation of late spermatogonia in transgenic mice overexpressing the human ornithine decarboxylase gene. Mol. Endocrinol. 7, 1430-1436.
-
(1993)
Mol. Endocrinol.
, vol.7
, pp. 1430-1436
-
-
Hakovirta, H.1
Keiski, A.2
Toppari, J.3
Halmekytö, M.4
Alhonen, L.5
Jänne, J.6
Parvinen, M.7
-
35
-
-
0034712739
-
Discovery of a spermatogenesis stage-specific ornithine decarboxylase antizyme: Antizyme 3
-
Ivanov, I.P., Rohrwasser, A., Terreros, D.A., Gesteland, R.F. & Atkins, J.F. (2000) Discovery of a spermatogenesis stage-specific ornithine decarboxylase antizyme: antizyme 3. Proc. Natl Acad. Sci. USA 97, 4808-4813.
-
(2000)
Proc. Natl Acad. Sci. USA
, vol.97
, pp. 4808-4813
-
-
Ivanov, I.P.1
Rohrwasser, A.2
Terreros, D.A.3
Gesteland, R.F.4
Atkins, J.F.5
-
36
-
-
0034712967
-
Polyamines in spermiogenesis: Not now, darling
-
Coffino, P. (2000) Polyamines in spermiogenesis: not now, darling. Proc. Natl Acad. Sci. USA 97, 4421-4423.
-
(2000)
Proc. Natl Acad. Sci. USA
, vol.97
, pp. 4421-4423
-
-
Coffino, P.1
-
37
-
-
0027263467
-
Transformation of NIH/3T3 cells by ornithine decarboxylase overexpression
-
Moshier, J.A., Dosescu, J., Skunca, M. & Luk, G.D. (1993) Transformation of NIH/3T3 cells by ornithine decarboxylase overexpression. Cancer Res. 53, 2618-2622.
-
(1993)
Cancer Res.
, vol.53
, pp. 2618-2622
-
-
Moshier, J.A.1
Dosescu, J.2
Skunca, M.3
Luk, G.D.4
-
38
-
-
0026683752
-
Ornithine decarboxylase acitivity is critical for cell transformation
-
Auvinen, M., Paasinen, A., Andersson, L.C. & Hölttä, E. (1992) Ornithine decarboxylase acitivity is critical for cell transformation. Nature 360, 355-358.
-
(1992)
Nature
, vol.360
, pp. 355-358
-
-
Auvinen, M.1
Paasinen, A.2
Andersson, L.C.3
Hölttä, E.4
-
39
-
-
0030834335
-
Human ornithine decarboxylase-overproducing NIH3T3 cells induce rapidly growing, highly vascularized tumors in nude mice
-
Auvinen, M., Laine, A., Paasinen-Sohns, A., Kangas, A., Kangas, L., Saksela, O., Andersson, L.C. & Hölttä, E. (1997) Human ornithine decarboxylase-overproducing NIH3T3 cells induce rapidly growing, highly vascularized tumors in nude mice. Cancer Res. 57, 3016-3025.
-
(1997)
Cancer Res.
, vol.57
, pp. 3016-3025
-
-
Auvinen, M.1
Laine, A.2
Paasinen-Sohns, A.3
Kangas, A.4
Kangas, L.5
Saksela, O.6
Andersson, L.C.7
Hölttä, E.8
-
40
-
-
0028805673
-
Life-long over-expression of ornithine decarboxylase (ODC) gene in transgenic mice does not lead to generally enhanced tumorigenesis or neuronal degeneration
-
Alhonen, L., Halmekytö, M., Kosma, V.-M., Wahlfors, J., Kauppinen, R. & Jänne, J. (1995) Life-long over-expression of ornithine decarboxylase (ODC) gene in transgenic mice does not lead to generally enhanced tumorigenesis or neuronal degeneration. Int. J. Cancer 63, 402-404.
-
(1995)
Int. J. Cancer
, vol.63
, pp. 402-404
-
-
Alhonen, L.1
Halmekytö, M.2
Kosma, V.-M.3
Wahlfors, J.4
Kauppinen, R.5
Jänne, J.6
-
41
-
-
0342894771
-
Effects of chronically elevated growth hormone levels on polyamine metabolism in elderly transgenic mice
-
Gritli-Linde, A., Björkman, U., Holm, I., Törnell, J. & Linde, A. (1997) Effects of chronically elevated growth hormone levels on polyamine metabolism in elderly transgenic mice. Mol. Cell. Endocrinol. 126, 49-58.
-
(1997)
Mol. Cell. Endocrinol.
, vol.126
, pp. 49-58
-
-
Gritli-Linde, A.1
Björkman, U.2
Holm, I.3
Törnell, J.4
Linde, A.5
-
42
-
-
0242570626
-
Abnormal ornithine decarboxylase activity in transgenic mice increases tumor formation and infertility
-
Kilpeläinen, P.T., Saarimies, J., Kontusaari, S.I., Järvinen, M.J., Soler, A.P., Kallioinen, M.J. & Hietala, O.A. (2001) Abnormal ornithine decarboxylase activity in transgenic mice increases tumor formation and infertility. Int. J. Biochem. Cell. Biol. 33, 507-520.
-
(2001)
Int. J. Biochem. Cell. Biol.
, vol.33
, pp. 507-520
-
-
Kilpeläinen, P.T.1
Saarimies, J.2
Kontusaari, S.I.3
Järvinen, M.J.4
Soler, A.P.5
Kallioinen, M.J.6
Hietala, O.A.7
-
43
-
-
0037222224
-
A low molecular weight antioxidant decreases weight and lowers tumor incidence
-
Mitchell, J.B., Xavier, S., DeLuca, A.M., Sowers, A.L., Cook, J.A., Krishna, M.C., Hahn, S.M. & Russo, A. (2003) A low molecular weight antioxidant decreases weight and lowers tumor incidence. Free Radic. Biol. Med. 34, 93-102.
-
(2003)
Free Radic. Biol. Med.
, vol.34
, pp. 93-102
-
-
Mitchell, J.B.1
Xavier, S.2
DeLuca, A.M.3
Sowers, A.L.4
Cook, J.A.5
Krishna, M.C.6
Hahn, S.M.7
Russo, A.8
-
44
-
-
0026779333
-
Enhanced papilloma formation in response to skin tumor promotion in transgenic mice overexpressing the human ornithine decarboxylase gene
-
Halmekytö, M., Syrjänen, K., Jänne, J. & Alhonen, L. (1992) Enhanced papilloma formation in response to skin tumor promotion in transgenic mice overexpressing the human ornithine decarboxylase gene. Biochem. Biophys. Res. Commun. 187, 493-497.
-
(1992)
Biochem. Biophys. Res. Commun.
, vol.187
, pp. 493-497
-
-
Halmekytö, M.1
Syrjänen, K.2
Jänne, J.3
Alhonen, L.4
-
45
-
-
0029050287
-
Increased frequency of spontaneous skin tumors in transgenic mice which overexpress ornithine decarboxylase
-
Megosh, L., Gilmour, S.K., Rosson, D., Soler, A.P., Blessing, M., Sawicki, J.A. & O'Brien, T.G. (1995) Increased frequency of spontaneous skin tumors in transgenic mice which overexpress ornithine decarboxylase. Cancer Res. 55, 4205-4209.
-
(1995)
Cancer Res.
, vol.55
, pp. 4205-4209
-
-
Megosh, L.1
Gilmour, S.K.2
Rosson, D.3
Soler, A.P.4
Blessing, M.5
Sawicki, J.A.6
O'Brien, T.G.7
-
46
-
-
0004713598
-
Catalytic irreversible inhibition of mammalian ornithine decarboxylase (EC.4.1.1.17) by substrate and product analogues
-
Metcalf, B.W., Bey, P., Danzin, C., Jung, M.J., Casara, J. & Vevert, J.P. (1978) Catalytic irreversible inhibition of mammalian ornithine decarboxylase (EC.4.1.1.17) by substrate and product analogues. J. Am. Chem. Soc. 100, 2551-2553.
-
(1978)
J. Am. Chem. Soc.
, vol.100
, pp. 2551-2553
-
-
Metcalf, B.W.1
Bey, P.2
Danzin, C.3
Jung, M.J.4
Casara, J.5
Vevert, J.P.6
-
47
-
-
0029883123
-
Modulation of murine hair follicle function by alterations in ornithine decarboxylase activity
-
Soler, A.P., Gilliard, G., Megosh, L.C. & O'Brien, T.G. (1996) Modulation of murine hair follicle function by alterations in ornithine decarboxylase activity. J. Invest. Dermatol. 106, 1108-1113.
-
(1996)
J. Invest. Dermatol.
, vol.106
, pp. 1108-1113
-
-
Soler, A.P.1
Gilliard, G.2
Megosh, L.C.3
O'Brien, T.G.4
-
48
-
-
0030741841
-
Ornithine decarboxylase overexpression is a sufficient condition for tumor promotion in mouse skin
-
O'Brien, T.G., Megosh, L.C., Gilliard, G. & Soler, A.P. (1997) Ornithine decarboxylase overexpression is a sufficient condition for tumor promotion in mouse skin. Cancer Res. 57, 2630-2637.
-
(1997)
Cancer Res.
, vol.57
, pp. 2630-2637
-
-
O'Brien, T.G.1
Megosh, L.C.2
Gilliard, G.3
Soler, A.P.4
-
49
-
-
0032522797
-
Polyamines regulate expression of the neoplastic phenotype in mouse skin
-
Soler, A.P., Gilliard, G., Megosh, L. & George, K.O.B. (1998) Polyamines regulate expression of the neoplastic phenotype in mouse skin. Cancer Res. 58, 1654-1659.
-
(1998)
Cancer Res.
, vol.58
, pp. 1654-1659
-
-
Soler, A.P.1
Gilliard, G.2
Megosh, L.3
George, K.O.B.4
-
50
-
-
0031691298
-
Co-operation between follicular ornithine decarboxylase and v-Ha-ras induces spontaneous papillomas and malignant conversion in transgenic skin
-
Smith, M.K., Trempus, C.S. & Gilmour, S.K. (1998) Co-operation between follicular ornithine decarboxylase and v-Ha-ras induces spontaneous papillomas and malignant conversion in transgenic skin. Carcinogenesis 19, 1409-1415.
-
(1998)
Carcinogenesis
, vol.19
, pp. 1409-1415
-
-
Smith, M.K.1
Trempus, C.S.2
Gilmour, S.K.3
-
51
-
-
0034847478
-
A definitive role of ornithine decarboxylase in photocarcinogenesis
-
Ahmad, N., Gilliam, A.C., Katiyar, S.K., O'Brien, T.G. & Mukhtar, H. (2001) A definitive role of ornithine decarboxylase in photocarcinogenesis. Am. J. Pathol. 159, 885-892.
-
(2001)
Am. J. Pathol.
, vol.159
, pp. 885-892
-
-
Ahmad, N.1
Gilliam, A.C.2
Katiyar, S.K.3
O'Brien, T.G.4
Mukhtar, H.5
-
52
-
-
0036013932
-
Overexpression of a dominant-negative ornithine decarboxylase in mouse skin: Effect on enzyme activity and papilloma formation
-
Shantz, L.M., Guo, Y., Sawicki, J.A., Pegg, A.E. & O'Brien, T.G. (2002) Overexpression of a dominant-negative ornithine decarboxylase in mouse skin: effect on enzyme activity and papilloma formation. Carcinogenesis 23, 657-664.
-
(2002)
Carcinogenesis
, vol.23
, pp. 657-664
-
-
Shantz, L.M.1
Guo, Y.2
Sawicki, J.A.3
Pegg, A.E.4
O'Brien, T.G.5
-
53
-
-
0034100422
-
High levels of intracellular polyamines promote histone acetyltransferase activity resulting in chromatin hyperacetylation
-
Hobbs, C.A. & Gilmour, S.K. (2000) High levels of intracellular polyamines promote histone acetyltransferase activity resulting in chromatin hyperacetylation. J. Cell. Biochem. 77, 345-360.
-
(2000)
J. Cell. Biochem.
, vol.77
, pp. 345-360
-
-
Hobbs, C.A.1
Gilmour, S.K.2
-
54
-
-
0036142967
-
Deregulation of polyamine biosynthesis alters intrinsic histone acetyltransferase and deacetylase activities in murine skin and tumors
-
Hobbs, C.A., Paul, B.A. & Gilmour, S.K. (2002) Deregulation of polyamine biosynthesis alters intrinsic histone acetyltransferase and deacetylase activities in murine skin and tumors. Cancer Res. 62, 67-74.
-
(2002)
Cancer Res.
, vol.62
, pp. 67-74
-
-
Hobbs, C.A.1
Paul, B.A.2
Gilmour, S.K.3
-
55
-
-
0036291267
-
Overexpression of arginase I in enterocytes of transgenic mice elicits a selective arginine deficiency and affects skin, muscle, and lymphoid development
-
de Jonge, W.J., Hallemeesch, M.M., Kwikkers, K.L., Ruijter, J.M., de Gier-de Vries, C., van Roon, M.A., Meijer, A.J., Marescau, B., de Deyn, P.P., Deutz, N.E. & Lamers, W.H. (2002) Overexpression of arginase I in enterocytes of transgenic mice elicits a selective arginine deficiency and affects skin, muscle, and lymphoid development. Am. J. Clin. Nutr. 76, 128-140.
-
(2002)
Am. J. Clin. Nutr.
, vol.76
, pp. 128-140
-
-
De Jonge, W.J.1
Hallemeesch, M.M.2
Kwikkers, K.L.3
Ruijter, J.M.4
De Gier-de Vries, C.5
Van Roon, M.A.6
Meijer, A.J.7
Marescau, B.8
De Deyn, P.P.9
Deutz, N.E.10
Lamers, W.H.11
-
56
-
-
0026744247
-
Polyamine metabolism in different pathological states of the brain
-
Paschen, W. (1992) Polyamine metabolism in different pathological states of the brain. Mol. Chem. Neuropathol. 16, 241-271.
-
(1992)
Mol. Chem. Neuropathol.
, vol.16
, pp. 241-271
-
-
Paschen, W.1
-
57
-
-
0029565273
-
Transgenic animals as models in the study of the neurobiological role of polyamines
-
Kauppinen, R.A. & Alhonen, L.I. (1995) Transgenic animals as models in the study of the neurobiological role of polyamines. Progr. Neurobiol. 47, 545-563.
-
(1995)
Progr. Neurobiol.
, vol.47
, pp. 545-563
-
-
Kauppinen, R.A.1
Alhonen, L.I.2
-
58
-
-
0024448447
-
Effects of polyamines on the binding of [3H]MK-801 to the N-methyl-D-aspartate receptor: Pharmacological evidence for the existence of a polyamine recognition site
-
Williams, K., Romano, C. & Molinoff, P.B. (1989) Effects of polyamines on the binding of [3H]MK-801 to the N-methyl-D-aspartate receptor: pharmacological evidence for the existence of a polyamine recognition site. Mol. Pharmacol. 36, 575-581.
-
(1989)
Mol. Pharmacol.
, vol.36
, pp. 575-581
-
-
Williams, K.1
Romano, C.2
Molinoff, P.B.3
-
59
-
-
0025063670
-
Characterization of polyamines having agonist, antagonist, and inverse effects at the polyamine recognition site of the NMDA receptor
-
Williams, K., Dawson, V.L., Romano, C., Dichter, M.A. & Molinoff, P.B. (1990) Characterization of polyamines having agonist, antagonist, and inverse effects at the polyamine recognition site of the NMDA receptor. Neuron 5, 199-208.
-
(1990)
Neuron
, vol.5
, pp. 199-208
-
-
Williams, K.1
Dawson, V.L.2
Romano, C.3
Dichter, M.A.4
Molinoff, P.B.5
-
60
-
-
0027326866
-
Elevated seiqure threshold and impaired spatial learning in transgenic mice with putrescine overproduction in the brain
-
Halonen, T., Sivenius, J., Miettinen, R., Halmekytö, M., Kauppinen, R., Sinervirta, R., Alakuijala, L., Alhonen, L., MacDonald, E., Jänne, J., et al. (1993) Elevated seiqure threshold and impaired spatial learning in transgenic mice with putrescine overproduction in the brain. Eur. J. Neurosci. 5, 1233-1239.
-
(1993)
Eur. J. Neurosci.
, vol.5
, pp. 1233-1239
-
-
Halonen, T.1
Sivenius, J.2
Miettinen, R.3
Halmekytö, M.4
Kauppinen, R.5
Sinervirta, R.6
Alakuijala, L.7
Alhonen, L.8
MacDonald, E.9
Jänne, J.10
-
61
-
-
0021260967
-
Magnesium gates glutamate-activated channels in mouse central neurones
-
Nowak, L., Bregestovski, P., Ascher, P., Herbet, A. & Prochiantz, A. (1984) Magnesium gates glutamate-activated channels in mouse central neurones. Nature 307, 462-465.
-
(1984)
Nature
, vol.307
, pp. 462-465
-
-
Nowak, L.1
Bregestovski, P.2
Ascher, P.3
Herbet, A.4
Prochiantz, A.5
-
62
-
-
0026528742
-
2+ concentration in the brain of transgenic mice overexpressing human ornithine decarboxylase gene
-
2+ concentration in the brain of transgenic mice overexpressing human ornithine decarboxylase gene. J. Neurochem. 58, 831-836.
-
(1992)
J. Neurochem.
, vol.58
, pp. 831-836
-
-
Kauppinen, R.A.1
Halmekytö, M.2
Alhonen, L.3
Jänne, J.4
-
63
-
-
0023177641
-
NMDA receptors of dentate gyrus granule cells participate in synaptic transmission following kindling
-
Mody, I. & Heinemann, U. (1987) NMDA receptors of dentate gyrus granule cells participate in synaptic transmission following kindling. Nature 326, 701-704.
-
(1987)
Nature
, vol.326
, pp. 701-704
-
-
Mody, I.1
Heinemann, U.2
-
64
-
-
0023205908
-
Single unit activity in the rat hippocampus during a spatial memory task
-
O'Keefe, J. & Speakman, A. (1987) Single unit activity in the rat hippocampus during a spatial memory task. Exp. Brain Res. 68, 1-27.
-
(1987)
Exp. Brain Res.
, vol.68
, pp. 1-27
-
-
O'Keefe, J.1
Speakman, A.2
-
65
-
-
0029835015
-
Induced expression of neurotrophins in transgenic mice over-expressing ornithine decarboxylase and overproducing putrescine
-
Reeben, M., Arbatova, J., Palgi, J., Miettinen, R., Halmekytö, M., Alhonen, L., Jänne, J., Riekkinen, P. Sr & Saarma, M. (1996) Induced expression of neurotrophins in transgenic mice over-expressing ornithine decarboxylase and overproducing putrescine. J. Neurosci. Res. 45, 542-548.
-
(1996)
J. Neurosci. Res.
, vol.45
, pp. 542-548
-
-
Reeben, M.1
Arbatova, J.2
Palgi, J.3
Miettinen, R.4
Halmekytö, M.5
Alhonen, L.6
Jänne, J.7
Riekkinen Sr., P.8
Saarma, M.9
-
66
-
-
0029097435
-
Cerebral energy metabolism and immediate early gene induction following severe incomplete ischaemia in transgenic mice overexpressing the human ornithine decarboxylase gene: Evidence that putrescine is not neurotoxic in vivo
-
Lukkarinen, J., Kauppinen, R.A., Koistinaho, J., Halmekytö, M., Alhonen, L. & Jänne, J. (1995) Cerebral energy metabolism and immediate early gene induction following severe incomplete ischaemia in transgenic mice overexpressing the human ornithine decarboxylase gene: evidence that putrescine is not neurotoxic in vivo. Eur. J. Neurosci. 7, 1840-1849.
-
(1995)
Eur. J. Neurosci.
, vol.7
, pp. 1840-1849
-
-
Lukkarinen, J.1
Kauppinen, R.A.2
Koistinaho, J.3
Halmekytö, M.4
Alhonen, L.5
Jänne, J.6
-
67
-
-
0342813146
-
Transgenic rats as models for studying the role of ornithine decarboxylase expression in permanent middle cerebral artery occlusion
-
Lukkarinen, J., Gröhn, O., Sinervirta, R., Järvinen, A., Kauppinen, R.A., Jänne, J. & Alhonen, L. (1997) Transgenic rats as models for studying the role of ornithine decarboxylase expression in permanent middle cerebral artery occlusion. Stroke 28, 639-645.
-
(1997)
Stroke
, vol.28
, pp. 639-645
-
-
Lukkarinen, J.1
Gröhn, O.2
Sinervirta, R.3
Järvinen, A.4
Kauppinen, R.A.5
Jänne, J.6
Alhonen, L.7
-
68
-
-
0345711479
-
Enhanced ornithine decarboxylase activity is associated with attenuated rate of damage evolution and reduction of infarct volume in transient middle cerebral artery occlusion in the rat
-
Lukkarinen, J.A., Gröhn, O.H., Alhonen, L.I., Jänne, J. & Kauppinen, R.A. (1999) Enhanced ornithine decarboxylase activity is associated with attenuated rate of damage evolution and reduction of infarct volume in transient middle cerebral artery occlusion in the rat. Brain Res. 826, 325-329.
-
(1999)
Brain Res.
, vol.826
, pp. 325-329
-
-
Lukkarinen, J.A.1
Gröhn, O.H.2
Alhonen, L.I.3
Jänne, J.4
Kauppinen, R.A.5
-
69
-
-
0031844346
-
Neuroprotective role of ornithine decarboxylase activation in transient cerebral focal ischemia: A study using ornithine decarboxylase-over-expressing transgenic rats
-
Lukkarinen, J.A., Kauppinen, R.A., Gröhn, O.H.J., Oja, J.M.E., Sinervirta, R., Alhonen, L.I. & Jänne, J. (1998) Neuroprotective role of ornithine decarboxylase activation in transient cerebral focal ischemia: a study using ornithine decarboxylase-over-expressing transgenic rats. Eur. J. Neurosci. 10, 2046-2055.
-
(1998)
Eur. J. Neurosci.
, vol.10
, pp. 2046-2055
-
-
Lukkarinen, J.A.1
Kauppinen, R.A.2
Gröhn, O.H.J.3
Oja, J.M.E.4
Sinervirta, R.5
Alhonen, L.I.6
Jänne, J.7
-
70
-
-
0019084839
-
Polyamine metabolism during cardiac hypertrophy
-
Pegg, A.E. & Hibasami, H. (1980) Polyamine metabolism during cardiac hypertrophy. Am. J. Physiol. 239, E372-E378.
-
(1980)
Am. J. Physiol.
, vol.239
-
-
Pegg, A.E.1
Hibasami, H.2
-
71
-
-
0031962040
-
Polyamine-mediated heart hypertrophy induced by clenbuterol in the mouse
-
Cubria, J.C., Reguera, R., Balana-Fouce, R., Ordonez, C. & Ordonez, D. (1998) Polyamine-mediated heart hypertrophy induced by clenbuterol in the mouse. J. Pharm. Pharmacol. 50, 91-96.
-
(1998)
J. Pharm. Pharmacol.
, vol.50
, pp. 91-96
-
-
Cubria, J.C.1
Reguera, R.2
Balana-Fouce, R.3
Ordonez, C.4
Ordonez, D.5
-
72
-
-
0019809660
-
Effect of alpha-difluoromethylornithine on cardiac polyamine content and hypertrophy
-
Pegg, A.E. (1981) Effect of alpha-difluoromethylornithine on cardiac polyamine content and hypertrophy. J. Mol. Cell. Cardial. 13, 881-887.
-
(1981)
J. Mol. Cell. Cardial.
, vol.13
, pp. 881-887
-
-
Pegg, A.E.1
-
73
-
-
0035881738
-
Targeted over-expression of ornithine decarboxylase enhances beta-adrenergic agonist-induced cardiac hypertrophy
-
Shantz, L.M., Feith, D.J. & Pegg, A.E. (2001) Targeted over-expression of ornithine decarboxylase enhances beta-adrenergic agonist-induced cardiac hypertrophy. Biochem. J. 358, 25-32.
-
(2001)
Biochem. J.
, vol.358
, pp. 25-32
-
-
Shantz, L.M.1
Feith, D.J.2
Pegg, A.E.3
-
74
-
-
0027984375
-
Potassium channel block by cytoplasmic polyamines as the mechanism of intrinsic rectification
-
Lopatin, A.N., Makhina, E.N. & Nichols, C.G. (1994) Potassium channel block by cytoplasmic polyamines as the mechanism of intrinsic rectification. Nature 372, 366-369.
-
(1994)
Nature
, vol.372
, pp. 366-369
-
-
Lopatin, A.N.1
Makhina, E.N.2
Nichols, C.G.3
-
76
-
-
0033747576
-
Modulation of potassium channels in the hearts of transgenic and mutant mice with altered polyamine biosynthesis
-
Lopatin, A.N., Shantz, L.M., Mackintosh, C.A., Nichols, C.G. & Pegg, A.E. (2000) Modulation of potassium channels in the hearts of transgenic and mutant mice with altered polyamine biosynthesis. J. Mol. Cell. Cardiol. 32, 2007-2024.
-
(2000)
J. Mol. Cell. Cardiol.
, vol.32
, pp. 2007-2024
-
-
Lopatin, A.N.1
Shantz, L.M.2
Mackintosh, C.A.3
Nichols, C.G.4
Pegg, A.E.5
-
77
-
-
0030890813
-
Transgenic mice over-expressing ornithine and S-adenosylmethionine decarboxylases maintain a physiological polyamine homeostasis in their tissues
-
Heljasvaara, R., Veress, I., Halmekytö, M., Alhonen, L., Jänne, J., Laajala, P. & Pajunen, A. (1997) Transgenic mice over-expressing ornithine and S-adenosylmethionine decarboxylases maintain a physiological polyamine homeostasis in their tissues. Biochem. J. 323, 457-462.
-
(1997)
Biochem. J.
, vol.323
, pp. 457-462
-
-
Heljasvaara, R.1
Veress, I.2
Halmekytö, M.3
Alhonen, L.4
Jänne, J.5
Laajala, P.6
Pajunen, A.7
-
78
-
-
0027164496
-
Transgenic mice over-expressing the human spermidine synthase gene
-
Kauppinen, L., Myöhänen, S., Halmekytö, M., Alhonen, L. & Jänne, J. (1993) Transgenic mice over-expressing the human spermidine synthase gene. Biochem. J. 293, 513-516.
-
(1993)
Biochem. J.
, vol.293
, pp. 513-516
-
-
Kauppinen, L.1
Myöhänen, S.2
Halmekytö, M.3
Alhonen, L.4
Jänne, J.5
-
80
-
-
0035447084
-
Concurrent overexpression of ornithine decarboxylase and spermidine/spermine N1-acetyltransferase further accelerates the catabolism of hepatic polyamines in transgenic mice
-
Suppola, S., Heikkinen, S., Parkkinen, J.J., Uusi-Oukari, M., Korhonen, V.P., Keinänen, T., Alhonen, L. & Jänne, J. (2001) Concurrent overexpression of ornithine decarboxylase and spermidine/spermine N1-acetyltransferase further accelerates the catabolism of hepatic polyamines in transgenic mice. Biochem. J. 358, 343-348.
-
(2001)
Biochem. J.
, vol.358
, pp. 343-348
-
-
Suppola, S.1
Heikkinen, S.2
Parkkinen, J.J.3
Uusi-Oukari, M.4
Korhonen, V.P.5
Keinänen, T.6
Alhonen, L.7
Jänne, J.8
-
82
-
-
0030053806
-
1-acetyltransferase (SSAT) gene in human lung carcinoma cells
-
1-acetyltransferase (SSAT) gene in human lung carcinoma cells. Biochem. J. 313, 691-696.
-
(1996)
Biochem. J.
, vol.313
, pp. 691-696
-
-
Xiao, L.1
Casero, R.A.2
-
85
-
-
0024588671
-
Structure-function correlations of polyamine analog-induced increases in spermidine/spermine acetyltransferase activity
-
Libby, P.R., Bergeron, R.J. & Porter, C.W. (1989) Structure-function correlations of polyamine analog-induced increases in spermidine/spermine acetyltransferase activity. Biochem. Pharmacol. 38, 1435-1442.
-
(1989)
Biochem. Pharmacol.
, vol.38
, pp. 1435-1442
-
-
Libby, P.R.1
Bergeron, R.J.2
Porter, C.W.3
-
86
-
-
0031891861
-
1- acetyltransferase
-
1- acetyltransferase. J. Biol. Chem. 273, 1964-1969.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 1964-1969
-
-
Alhonen, L.1
Karppinen, A.2
Uusi-Oukari, M.3
Vujcic, S.4
Korhonen, V.-P.5
Halmekytö, M.6
Kramer, D.L.7
Hines, R.8
Jänne, J.9
Porter, C.W.10
-
87
-
-
0033104908
-
1-acetyltransferase under the control of mouse metallothionein I promoter in transgenic mice: Evidence for a striking post-transcriptional regulation of transgene expression by a polyamine analogue
-
1-acetyltransferase under the control of mouse metallothionein I promoter in transgenic mice: evidence for a striking post-transcriptional regulation of transgene expression by a polyamine analogue. Biochem. J. 338, 311-316.
-
(1999)
Biochem. J.
, vol.338
, pp. 311-316
-
-
Suppola, S.1
Pietilä, M.2
Parkkinen, J.J.3
Korhonen, V.P.4
Alhonen, L.5
Halmekytö, M.6
Porter, C.W.7
Jänne, J.8
-
88
-
-
0036308416
-
1-acetyltransferase mRNA in the human kidney cells infected by venezuelan equine encephalitis and tick-borne encephalitis viruses
-
1- acetyltransferase mRNA in the human kidney cells infected by venezuelan equine encephalitis and tick-borne encephalitis viruses. Virology 297, 163-171.
-
(2002)
Virology
, vol.297
, pp. 163-171
-
-
Nikiforova, N.N.1
Velikodvorskaja, T.V.2
Kachko, A.V.3
Nikolaev, L.G.4
Monastyrskaya, G.S.5
Lukyanov, S.A.6
Konovalova, S.N.7
Protopopova, E.V.8
Svyatchenko, V.A.9
Kiselev, N.N.10
Loktev, V.B.11
Sverdlov, E.D.12
-
89
-
-
0036306242
-
11-diethylnorspermine in patients with non-small cell lung cancer
-
11-diethylnorspermine in patients with non-small cell lung cancer. Clin. Cancer Res. 8, 684-690.
-
(2002)
Clin. Cancer Res.
, vol.8
, pp. 684-690
-
-
Hahm, H.A.1
Ettinger, D.S.2
Bowling, K.3
Hoker, B.4
Chen, T.L.5
Zabelina, Y.6
Casero Jr., R.A.7
-
91
-
-
0025833516
-
1-acetyltransferase activity, polyamine pool depletion, and growth inhibition in human melanoma cell lines
-
1-acetyltransferase activity, polyamine pool depletion, and growth inhibition in human melanoma cell lines. Cancer Res. 51, 3715-3720.
-
(1991)
Cancer Res.
, vol.51
, pp. 3715-3720
-
-
Porter, C.W.1
Ganis, B.2
Libby, P.R.3
Bergeron, R.J.4
-
92
-
-
0026665552
-
12-bis(ethyl)spermine, on polyamine metabolism and cell growth in human melanoma cell lines and melanocytes
-
12- bis(ethyl)spermine, on polyamine metabolism and cell growth in human melanoma cell lines and melanocytes. Anticancer Res. 12, 1083-1090.
-
(1992)
Anticancer Res.
, vol.12
, pp. 1083-1090
-
-
Shappell, N.W.1
Miller, J.T.2
Bergeron, R.J.3
Porter, C.W.4
-
98
-
-
0036479205
-
1-acetyltransferase (SSAT)
-
1-acetyltransferase (SSAT). J. Biol. Chem. 277, 3647-3657.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 3647-3657
-
-
Min, S.H.1
Simmen, R.C.2
Alhonen, L.3
Halmekytö, M.4
Porter, C.W.5
Jänne, J.6
Simmen, F.A.7
-
99
-
-
0000007639
-
The pharmacology of spermine and spermidine. Distribution and excretion
-
Rosenthal, S.M. & Tabor, C.W. (1956) The pharmacology of spermine and spermidine. Distribution and excretion. J. Pharmacol. Exp. Ther. 116, 131-138.
-
(1956)
J. Pharmacol. Exp. Ther.
, vol.116
, pp. 131-138
-
-
Rosenthal, S.M.1
Tabor, C.W.2
-
100
-
-
0024429955
-
Role of ornithine decarboxylase and polyamines in camostate (Foy-305)-induced pancreatic growth in rats
-
Löser, C., Fölsch, U.R., Cleffmann, U., Nustede, R. & Creuzfeldt, W. (1989) Role of ornithine decarboxylase and polyamines in camostate (Foy-305)-induced pancreatic growth in rats. Digestion 43, 98-112.
-
(1989)
Digestion
, vol.43
, pp. 98-112
-
-
Löser, C.1
Fölsch, U.R.2
Cleffmann, U.3
Nustede, R.4
Creuzfeldt, W.5
-
101
-
-
0023502374
-
Implication of ornithine decarboxylase and polyamines in pancreatic growth of neonatal rats
-
Morisset, J. & Grondin, G. (1987) Implication of ornithine decarboxylase and polyamines in pancreatic growth of neonatal rats. Pancreas 2, 303-311.
-
(1987)
Pancreas
, vol.2
, pp. 303-311
-
-
Morisset, J.1
Grondin, G.2
-
102
-
-
0024473571
-
Inhibition of polyamine synthesis by α-difluoromethyl-ornithine and its effect on pancreatic secretion and growth in the rat
-
Haarstad, H., Skei, T. & Petersen, H. (1989) Inhibition of polyamine synthesis by α-difluoromethyl-ornithine and its effect on pancreatic secretion and growth in the rat. Scand. J. Gastroenterol. 24, 733-744.
-
(1989)
Scand. J. Gastroenterol.
, vol.24
, pp. 733-744
-
-
Haarstad, H.1
Skei, T.2
Petersen, H.3
-
103
-
-
0034682477
-
Activation of polyamine catabolism in transgenic rats induces acute pancreatitis
-
Alhonen, L., Parkkinen, J.J., Keinänen, T., Sinervirta, R., Herzig, K.H. & Jänne, J. (2000) Activation of polyamine catabolism in transgenic rats induces acute pancreatitis. Proc. Natl Acad. Sci. USA 97, 8290-8295.
-
(2000)
Proc. Natl Acad. Sci. USA
, vol.97
, pp. 8290-8295
-
-
Alhonen, L.1
Parkkinen, J.J.2
Keinänen, T.3
Sinervirta, R.4
Herzig, K.H.5
Jänne, J.6
-
104
-
-
0037131188
-
A polyamine analogue prevents acute pancreatitis and restores early liver regeneration in transgenic rats with activated polyamine catabolism
-
Räsänen, T.L., Alhonen, L., Sinervirta, R., Keinänen, T., Herzig, K.H., Suppola, S., Khomutov, A.R., Vepsäläinen, J. & Jänne, J. (2002) A polyamine analogue prevents acute pancreatitis and restores early liver regeneration in transgenic rats with activated polyamine catabolism. J. Biol. Chem. 277, 39867-39872.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 39867-39872
-
-
Räsänen, T.L.1
Alhonen, L.2
Sinervirta, R.3
Keinänen, T.4
Herzig, K.H.5
Suppola, S.6
Khomutov, A.R.7
Vepsäläinen, J.8
Jänne, J.9
-
105
-
-
0021287511
-
Gossypol: A potential antifertility agent for males
-
Qian, S.Z. & Wang, Z.G. (1984) Gossypol: a potential antifertility agent for males. Annu. Rev. Pharmacol. Toxicol. 24, 329-360.
-
(1984)
Annu. Rev. Pharmacol. Toxicol.
, vol.24
, pp. 329-360
-
-
Qian, S.Z.1
Wang, Z.G.2
-
107
-
-
3042855849
-
1-acetyltransferase
-
1-acetyltransferase. Scand. J. Gastroenterol. 38, 787-793.
-
(2003)
Scand. J. Gastroenterol.
, vol.38
, pp. 787-793
-
-
Räsänen, T.L.1
Alhonen, L.2
Sinervirta, R.3
Uimari, A.4
Kaasinen, K.5
Keinänen, T.6
Herzig, K.H.7
Jänne, J.8
-
108
-
-
0014377528
-
Stimulation of spermidine synthesis in the regenerating rat liver: Relation to increased ornithine decarboxylase activity
-
Jänne, J. & Raina, A. (1968) Stimulation of spermidine synthesis in the regenerating rat liver: relation to increased ornithine decarboxylase activity. Acta Chem. Scand. 22, 1349-1351.
-
(1968)
Acta Chem. Scand.
, vol.22
, pp. 1349-1351
-
-
Jänne, J.1
Raina, A.2
-
109
-
-
0014323475
-
Amine synthesis in rapidly growing tissues: Ornithine decarboxylase activity in regenerating rat liver, chick embryo, and various tumors
-
Russell, D. & Snyder, S.H. (1968) Amine synthesis in rapidly growing tissues: ornithine decarboxylase activity in regenerating rat liver, chick embryo, and various tumors. Proc. Natl Acad. Sci. USA 60, 1420-1427.
-
(1968)
Proc. Natl Acad. Sci. USA
, vol.60
, pp. 1420-1427
-
-
Russell, D.1
Snyder, S.H.2
-
110
-
-
0014184247
-
Studies on the biosynthetic pathway of polyamines in rat liver
-
Jänne, J. (1967) Studies on the biosynthetic pathway of polyamines in rat liver. Acta Physiol. Scand. Supplement 300, 1-71.
-
(1967)
Acta Physiol. Scand. Supplement
, vol.300
, pp. 1-71
-
-
Jänne, J.1
-
111
-
-
0016223725
-
Alpha-hydrazino-ornithine blocks net synthesis of putrescine but not of RNA and DNA
-
Harik, S.I., Hollenberg, M.D. & Snyder, S.H. (1974) Alpha-hydrazino-ornithine blocks net synthesis of putrescine but not of RNA and DNA. Nature 249, 250-251.
-
(1974)
Nature
, vol.249
, pp. 250-251
-
-
Harik, S.I.1
Hollenberg, M.D.2
Snyder, S.H.3
-
112
-
-
0020066391
-
Effect of alpha-difluoromethylornithine on polyamine and DNA synthesis in regenerating rat liver
-
Pösö, H. & Pegg, A.E. (1982) Effect of alpha- difluoromethylornithine on polyamine and DNA synthesis in regenerating rat liver. Biochim. Biophys. Acta 696, 179-186.
-
(1982)
Biochim. Biophys. Acta
, vol.696
, pp. 179-186
-
-
Pösö, H.1
Pegg, A.E.2
-
113
-
-
0037083984
-
Polyamines are required for the initiation of rat liver regeneration
-
Alhonen, L., Räsänen, T.L., Sinervirta, R., Parkkinen, J.J., Korhonen, V.P., Pietilä, M. & Jänne, J. (2002) Polyamines are required for the initiation of rat liver regeneration. Biochem. J. 362, 149-153.
-
(2002)
Biochem. J.
, vol.362
, pp. 149-153
-
-
Alhonen, L.1
Räsänen, T.L.2
Sinervirta, R.3
Parkkinen, J.J.4
Korhonen, V.P.5
Pietilä, M.6
Jänne, J.7
-
115
-
-
0028206682
-
Kainate-induced seizure activity stimulates the polyamine interconversion pathway in rat brain
-
Baudry, M. & Najm, I. (1994) Kainate-induced seizure activity stimulates the polyamine interconversion pathway in rat brain. Neurosci. Lett. 171, 151-154.
-
(1994)
Neurosci. Lett.
, vol.171
, pp. 151-154
-
-
Baudry, M.1
Najm, I.2
-
116
-
-
0026497926
-
Excitotoxic cell death
-
Choi, D.W. (1992) Excitotoxic cell death. J. Neurobiol. 23, 1261-1276.
-
(1992)
J. Neurobiol.
, vol.23
, pp. 1261-1276
-
-
Choi, D.W.1
-
118
-
-
0017647010
-
Pentylenetetrazol and penicillin are selective antagonists of GABA-mediated post-synaptic inhibition in cultured mammalian neurones
-
Macdonald, R.L. & Barker, J.L. (1977) Pentylenetetrazol and penicillin are selective antagonists of GABA-mediated post-synaptic inhibition in cultured mammalian neurones. Nature 267, 720-721.
-
(1977)
Nature
, vol.267
, pp. 720-721
-
-
Macdonald, R.L.1
Barker, J.L.2
-
119
-
-
0031578936
-
Age-related decrease in the antiseizure effect of ifenprodil against pentylenetetrazole in mice
-
Tsuda, M., Suzuki, T. & Misawa, M. (1997) Age-related decrease in the antiseizure effect of ifenprodil against pentylenetetrazole in mice. Brain Res. Dev. Brain Res. 104, 201-204.
-
(1997)
Brain Res. Dev. Brain Res.
, vol.104
, pp. 201-204
-
-
Tsuda, M.1
Suzuki, T.2
Misawa, M.3
-
120
-
-
0033976427
-
In vitro and in vivo characterization of conantokin-R, a selective NMDa receptor antagonist isolated from the venom of the fish-hunting snail Conus radiatus
-
White, H.S., McCabe, R.T., Armstrong, H., Donevan, S.D., Cruz, L.J., Abogadie, F.C., Torres, J., Rivier, J.E., Paarmann, I., Hollmann, M. & Olivera, B.M. (2000) In vitro and in vivo characterization of conantokin-R, a selective NMDA receptor antagonist isolated from the venom of the fish-hunting snail Conus radiatus. J. Pharmacol. Exp. Ther. 292, 425-432.
-
(2000)
J. Pharmacol. Exp. Ther.
, vol.292
, pp. 425-432
-
-
White, H.S.1
McCabe, R.T.2
Armstrong, H.3
Donevan, S.D.4
Cruz, L.J.5
Abogadie, F.C.6
Torres, J.7
Rivier, J.E.8
Paarmann, I.9
Hollmann, M.10
Olivera, B.M.11
-
121
-
-
0029871365
-
Interactions between ifenprodil and the NR2B subunit of the N-methyl-D-aspartate receptor
-
Gallagher, M.J., Huang, H., Pritchett, D.B. & Lynch, D.R. (1996) Interactions between ifenprodil and the NR2B subunit of the N-methyl-D- aspartate receptor. J. Biol. Chem. 271, 9603-9611.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 9603-9611
-
-
Gallagher, M.J.1
Huang, H.2
Pritchett, D.B.3
Lynch, D.R.4
-
122
-
-
0034520063
-
Attenuation of brain edema, blood-brain barrier breakdown, and injury volume by ifenprodil, a polyamine-site N-methyl-D-aspartate receptor antagonist, after experimental traumatic brain injury in rats
-
Dempsey, R.J., Baskaya, M.K. & Dogan, A. (2000) Attenuation of brain edema, blood-brain barrier breakdown, and injury volume by ifenprodil, a polyamine-site N-methyl-D-aspartate receptor antagonist, after experimental traumatic brain injury in rats. Neurosurgery 47, 399-404.
-
(2000)
Neurosurgery
, vol.47
, pp. 399-404
-
-
Dempsey, R.J.1
Baskaya, M.K.2
Dogan, A.3
-
123
-
-
0035291218
-
Regulation of cellular polyamines by antizyme
-
Coffino, P. (2001) Regulation of cellular polyamines by antizyme. Nat. Rev. Mol. Cell Biol. 2, 188-194.
-
(2001)
Nat. Rev. Mol. Cell Biol.
, vol.2
, pp. 188-194
-
-
Coffino, P.1
-
124
-
-
0028856010
-
Transfection of human melanoma cells with type I interleukin-1 (IL-1) recptor cDNA rendered them IL-1 responsive and revealed the importance of ODC activity downregulation in IL-1-induced growth inhibition
-
Yang, D., Hayashi, H., Hiyama, Y., Takii, T. & Onozaki, K. (1995) Transfection of human melanoma cells with type I interleukin-1 (IL-1) recptor cDNA rendered them IL-1 responsive and revealed the importance of ODC activity downregulation in IL-1-induced growth inhibition. J. Biochem. 118, 802-809.
-
(1995)
J. Biochem.
, vol.118
, pp. 802-809
-
-
Yang, D.1
Hayashi, H.2
Hiyama, Y.3
Takii, T.4
Onozaki, K.5
-
125
-
-
0032474907
-
Reduction of ornithine decarboxylase antizyme (ODC-Az) level in the 7,12-dimethylbenz(a)anthracene-induced hamster buccal pouch carcinogenesis model
-
Tsuji, T., Todd, R., Meyer, C., McBride, J., Liao, P.H., Huang, M.F., Chou, M.Y., Donoff, R.B. & Wong, D.T.W. (1998) Reduction of ornithine decarboxylase antizyme (ODC-Az) level in the 7,12-dimethylbenz(a)anthracene- induced hamster buccal pouch carcinogenesis model. Oncogene 16, 3379-3385.
-
(1998)
Oncogene
, vol.16
, pp. 3379-3385
-
-
Tsuji, T.1
Todd, R.2
Meyer, C.3
McBride, J.4
Liao, P.H.5
Huang, M.F.6
Chou, M.Y.7
Donoff, R.B.8
Wong, D.T.W.9
-
126
-
-
0028884169
-
Identification of an endogenous inhibitor of prostatic carcinoma cell growth
-
Smith, R.C., Litwin, M.S., Lu, Y. & Zetter, B.R. (1995) Identification of an endogenous inhibitor of prostatic carcinoma cell growth. Nat. Med. 1, 1040-1045.
-
(1995)
Nat. Med.
, vol.1
, pp. 1040-1045
-
-
Smith, R.C.1
Litwin, M.S.2
Lu, Y.3
Zetter, B.R.4
-
127
-
-
0033572568
-
Sensitivity to polyamine-induced growth arrest correlates with antizyme induction in prostate carcinoma cells
-
Koike, C., Chao, D.T. & Zetter, B.R. (1999) Sensitivity to polyamine-induced growth arrest correlates with antizyme induction in prostate carcinoma cells. Cancer Res. 59, 6109-6112.
-
(1999)
Cancer Res.
, vol.59
, pp. 6109-6112
-
-
Koike, C.1
Chao, D.T.2
Zetter, B.R.3
-
128
-
-
0034664956
-
Overexpression of antizyme in the hearts of transgenic mice prevents the isoprenaline-induced increase in cardiac ornithine decarboxylase activity and polyamines, but does not prevent cardiac hypertrophy
-
Mackintosh, C.A., Feith, D.J., Shantz, L.M. & Pegg, A.E. (2000) Overexpression of antizyme in the hearts of transgenic mice prevents the isoprenaline-induced increase in cardiac ornithine decarboxylase activity and polyamines, but does not prevent cardiac hypertrophy. Biochem. J. 350, 645-653.
-
(2000)
Biochem. J.
, vol.350
, pp. 645-653
-
-
Mackintosh, C.A.1
Feith, D.J.2
Shantz, L.M.3
Pegg, A.E.4
-
129
-
-
0019180698
-
Role of ornithine decarboxylase in cardiac growth and hypertrophy
-
Bartolome, J., Huguenard, J. & Slotkin, T.A. (1980) Role of ornithine decarboxylase in cardiac growth and hypertrophy. Science 210, 793-794.
-
(1980)
Science
, vol.210
, pp. 793-794
-
-
Bartolome, J.1
Huguenard, J.2
Slotkin, T.A.3
-
130
-
-
0035881620
-
Targeted antizyme expression in the skin of transgenic mice reduces tumor promoter induction of ornithine decarboxylase and decreases sensitivity to chemical carcinogenesis
-
Feith, D.J., Shantz, L.M. & Pegg, A.E. (2001) Targeted antizyme expression in the skin of transgenic mice reduces tumor promoter induction of ornithine decarboxylase and decreases sensitivity to chemical carcinogenesis. Cancer Res. 61, 6073-6081.
-
(2001)
Cancer Res.
, vol.61
, pp. 6073-6081
-
-
Feith, D.J.1
Shantz, L.M.2
Pegg, A.E.3
-
131
-
-
0000382583
-
Alpha-difluoromethylornithine, an irreversible inhibitor of ornithine decarboxylase, inhibits tumor promoter-induced polyamine accumulation and carcinogenesis in mouse skin
-
Weeks, C.E., Herman, A.L., Nelson, F.R. & Slaga, T.J. (1982) Alpha-difluoromethylornithine, an irreversible inhibitor of ornithine decarboxylase, inhibits tumor promoter-induced polyamine accumulation and carcinogenesis in mouse skin. Proc. Natl Acad. Sci. USA 79, 6028-6032.
-
(1982)
Proc. Natl Acad. Sci. USA
, vol.79
, pp. 6028-6032
-
-
Weeks, C.E.1
Herman, A.L.2
Nelson, F.R.3
Slaga, T.J.4
-
132
-
-
0020372815
-
Polyamine biosynthesis and skin tumor promotion: Inhibition of 12-o-tetra-decanoylphorbol-13-acetate-promoted mouse skin tumor formation by the irreversible inhibitor of ornithine decarboxylase alpha- difluoromethylornithine
-
Takigawa, M., Verm, A.K., Simsiman, R.C. & Boutwell, R.K. (1982) Polyamine biosynthesis and skin tumor promotion: inhibition of 12-o-tetra-decanoylphorbol-13-acetate-promoted mouse skin tumor formation by the irreversible inhibitor of ornithine decarboxylase alpha- difluoromethylornithine. Biochem. Biophys. Res. Commun. 105, 969-976.
-
(1982)
Biochem. Biophys. Res. Commun.
, vol.105
, pp. 969-976
-
-
Takigawa, M.1
Verm, A.K.2
Simsiman, R.C.3
Boutwell, R.K.4
-
133
-
-
0041853847
-
Antizyme overexpression in transgenic mice reduces cell proliferation, increases apoptosis, and reduces N-nitrosomethylbenzylamine-induced forestomach carcinogenesis
-
Fong, L.Y., Feith, D.J. & Pegg, A.E. (2003) Antizyme overexpression in transgenic mice reduces cell proliferation, increases apoptosis, and reduces N-nitrosomethylbenzylamine-induced forestomach carcinogenesis. Cancer Res. 63, 3945-3954.
-
(2003)
Cancer Res.
, vol.63
, pp. 3945-3954
-
-
Fong, L.Y.1
Feith, D.J.2
Pegg, A.E.3
-
134
-
-
0030018043
-
Comparative properties of arginases
-
Jenkinson, C.P., Grody, W.W. & Cederbaum, S.D. (1996) Comparative properties of arginases. Comp. Biochem. Physiol. Biochem. Mol. Biol. B 114, 107-132.
-
(1996)
Comp. Biochem. Physiol. Biochem. Mol. Biol. B
, vol.114
, pp. 107-132
-
-
Jenkinson, C.P.1
Grody, W.W.2
Cederbaum, S.D.3
-
135
-
-
0035138834
-
Generation of a mouse model for arginase II deficiency by targeted disruption of the arginase II gene
-
Shi, O., Morris, S.M. Jr, Zoghbi, H., Porter, C.W. & O'Brien, W.E. (2001) Generation of a mouse model for arginase II deficiency by targeted disruption of the arginase II gene. Mol. Cell. Biol. 21, 811-813.
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 811-813
-
-
Shi, O.1
Morris Jr., S.M.2
Zoghbi, H.3
Porter, C.W.4
O'Brien, W.E.5
-
136
-
-
0022573998
-
Effect of polyamine limitation on DNA synthesis and development of mouse preimplantation embryos in vitro
-
Zwierzchowski, L., Czlonkowska, M. & Guszkiewicz, A. (1986) Effect of polyamine limitation on DNA synthesis and development of mouse preimplantation embryos in vitro. J. Reprod. Fertil. 76, 115-121.
-
(1986)
J. Reprod. Fertil.
, vol.76
, pp. 115-121
-
-
Zwierzchowski, L.1
Czlonkowska, M.2
Guszkiewicz, A.3
-
137
-
-
0018385339
-
Inhibition of early embryogenic development in mice by alpha-difluoromethyl ornithine, an enzyme-activated irreversible inhibitor of 1-ornithine decarboxylase
-
Fozard, J.R., Grove, J., Part, M.L. & Prakash, N.J. (1979) Inhibition of early embryogenic development in mice by alpha-difluoromethyl ornithine, an enzyme-activated irreversible inhibitor of 1-ornithine decarboxylase. Br. J. Pharmacol. 66, 436P-437P.
-
(1979)
Br. J. Pharmacol.
, vol.66
-
-
Fozard, J.R.1
Grove, J.2
Part, M.L.3
Prakash, N.J.4
-
138
-
-
0018941081
-
Inhibition of murine embryonic development by alpha- difluoromethylornithine, an irreversible inhibitor of ornithine decarboxylase
-
Fozard, J.R., Part, M.-L., Prakash, N.J. & Grove, J. (1980) Inhibition of murine embryonic development by alpha-difluoromethylornithine, an irreversible inhibitor of ornithine decarboxylase. Eur. J. Pharmacol. 65, 379-391.
-
(1980)
Eur. J. Pharmacol.
, vol.65
, pp. 379-391
-
-
Fozard, J.R.1
Part, M.-L.2
Prakash, N.J.3
Grove, J.4
-
139
-
-
0034809529
-
The ornithine decarboxylase gene is essential for cell survival during early murine development
-
Pendeville, H., Carpino, N., Marine, J.-C., Takahashi, Y., Muller, M., Martial, J.A. & Cleveland, J.L. (2001) The ornithine decarboxylase gene is essential for cell survival during early murine development. Mol. Cell. Biol. 21, 6549-6558.
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 6549-6558
-
-
Pendeville, H.1
Carpino, N.2
Marine, J.-C.3
Takahashi, Y.4
Muller, M.5
Martial, J.A.6
Cleveland, J.L.7
-
140
-
-
0029044140
-
The ornithine decarboxylase gene of Caenorhabditis elegans: Cloning, mapping and mutagenesis
-
Macrae, M., Plasterk, R.H. & Coffino, P. (1995) The ornithine decarboxylase gene of Caenorhabditis elegans: cloning, mapping and mutagenesis. Genetics 140, 517-525.
-
(1995)
Genetics
, vol.140
, pp. 517-525
-
-
Macrae, M.1
Plasterk, R.H.2
Coffino, P.3
-
141
-
-
0032528253
-
Developmental effect of polyamine depletion in Caenorhabditis elegans
-
Macrae, M., Kramer, D.L. & Coffino, P. (1998) Developmental effect of polyamine depletion in Caenorhabditis elegans. Biochem. J. 333, 309-315.
-
(1998)
Biochem. J.
, vol.333
, pp. 309-315
-
-
Macrae, M.1
Kramer, D.L.2
Coffino, P.3
-
142
-
-
0036163891
-
Essential role of S-adenosylmethionine decarboxylase in mouse embryonic development
-
Nishimura, K., Nakatsu, F., Kashiwagi, K., Ohno, H., Saito, T. & Igarashi, K. (2002) Essential role of S-adenosylmethionine decarboxylase in mouse embryonic development. Genes Cells 7, 41-47.
-
(2002)
Genes Cells
, vol.7
, pp. 41-47
-
-
Nishimura, K.1
Nakatsu, F.2
Kashiwagi, K.3
Ohno, H.4
Saito, T.5
Igarashi, K.6
-
143
-
-
0028957676
-
Cloning and sequencing of an intronless Mouse S-adenosylmethionine decarboxylase gene coding for a functional enzyme strongly expressed in the liver
-
Persson, K., Holm, I. & Heby, O. (1995) Cloning and sequencing of an
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 5642-5648
-
-
Persson, K.1
Holm, I.2
Heby, O.3
-
144
-
-
0032563978
-
Effect of polyamine analogues on hypusine content in JURKAT T-cells
-
Bergeron, R.J., Weimar, W.R., Muller, R., Zimmerman, C.O., McCosar, B.H., Yao, H. & Smith, R.E. (1998) Effect of polyamine analogues on hypusine content in JURKAT T-cells. J. Med. Chem. 41, 3901-3908.
-
(1998)
J. Med. Chem.
, vol.41
, pp. 3901-3908
-
-
Bergeron, R.J.1
Weimar, W.R.2
Muller, R.3
Zimmerman, C.O.4
McCosar, B.H.5
Yao, H.6
Smith, R.E.7
-
145
-
-
0035138640
-
Spermine deficiency resulting from targeted disruption of the spermine synthase gene in embryonic stem cells leads to enhanced sensitivity to anti-proliferative drugs
-
Korhonen, V.-P., Niiranen, K., Halmekytö, M., Pietilä, M., Diegelman, P., Parkkinen, J.J., Eloranta, T., Porter, C.W., Alhonen, L. & Jänne, J. (2001) Spermine deficiency resulting from targeted disruption of the spermine synthase gene in embryonic stem cells leads to enhanced sensitivity to anti-proliferative drugs. Mol. Pharmacol. 59, 231-238.
-
(2001)
Mol. Pharmacol.
, vol.59
, pp. 231-238
-
-
Korhonen, V.-P.1
Niiranen, K.2
Halmekytö, M.3
Pietilä, M.4
Diegelman, P.5
Parkkinen, J.J.6
Eloranta, T.7
Porter, C.W.8
Alhonen, L.9
Jänne, J.10
-
146
-
-
0019741182
-
Some properties of the polyamine deprivation-inducible uptake system for methylglyoxal bis(guanylhydrazone) in tumor cells
-
Seppänen, P. (1981) Some properties of the polyamine deprivation-inducible uptake system for methylglyoxal bis(guanylhydrazone) in tumor cells. Acta Chem. Scand. B35, 731-736.
-
(1981)
Acta Chem. Scand. B
, vol.35
, pp. 731-736
-
-
Seppänen, P.1
-
147
-
-
0024233051
-
Mechanism of action of antitumor drug etoposide: A review
-
van Maanen, J.M., Retel, J., de Vries, J. & Pinedo, H.M. (1988) Mechanism of action of antitumor drug etoposide: a review. J. Natl Cancer Inst. 80, 1526-1533.
-
(1988)
J. Natl Cancer Inst.
, vol.80
, pp. 1526-1533
-
-
Van Maanen, J.M.1
Retel, J.2
De Vries, J.3
Pinedo, H.M.4
-
148
-
-
6844240235
-
Spermine deficiency in Gy mice caused by deletion of the spermine synthase gene
-
Lorenz, B., Francis, F., Gempel, K., Boddrich, A., Josten, M., Schmahl, W., Schmidt, J., Lehrach, H., Meitinger, T. & Strom, T.M. (1998) Spermine deficiency in Gy mice caused by deletion of the spermine synthase gene. Hum. Mol. Genet. 7, 541-547.
-
(1998)
Hum. Mol. Genet.
, vol.7
, pp. 541-547
-
-
Lorenz, B.1
Francis, F.2
Gempel, K.3
Boddrich, A.4
Josten, M.5
Schmahl, W.6
Schmidt, J.7
Lehrach, H.8
Meitinger, T.9
Strom, T.M.10
-
149
-
-
0343635917
-
The Gy mutation: Another cause of X-linked hypophosphatemia in mouse
-
Lyon, M.F., Scriver, C.R., Baker, L.R., Tenenhouse, H.S., Kronick, J. & Mandla, S. (1986) The Gy mutation: another cause of X-linked hypophosphatemia in mouse. Proc. Natl Acad. Sci. USA 83, 4899-4903.
-
(1986)
Proc. Natl Acad. Sci. USA
, vol.83
, pp. 4899-4903
-
-
Lyon, M.F.1
Scriver, C.R.2
Baker, L.R.3
Tenenhouse, H.S.4
Kronick, J.5
Mandla, S.6
-
150
-
-
0030938927
-
Pex/PEX tissue distribution and evidence for a deletion in the 3′ region of the Pex gene in X-linked hypophosphatemic mice
-
Beck, L., Soumounou, Y., Martel, J., Krishnamurthy, G., Gauthier, C., Goodyer, C.G. & Tenenhouse, H.S. (1997) Pex/PEX tissue distribution and evidence for a deletion in the 3′ region of the Pex gene in X-linked hypophosphatemic mice. J. Clin. Invest. 99, 1200-1209.
-
(1997)
J. Clin. Invest.
, vol.99
, pp. 1200-1209
-
-
Beck, L.1
Soumounou, Y.2
Martel, J.3
Krishnamurthy, G.4
Gauthier, C.5
Goodyer, C.G.6
Tenenhouse, H.S.7
-
151
-
-
0034536576
-
Skin fibroblasts from spermine synthase-deficient hemizygous gyro male (Gy/Y) mice overproduce spermidine and exhibit increased resistance to oxidative stress but decreased resistance to UV irradiation
-
Nilsson, J., Gritli-Linde, A. & Heby, O. (2000) Skin fibroblasts from spermine synthase-deficient hemizygous gyro male (Gy/Y) mice overproduce spermidine and exhibit increased resistance to oxidative stress but decreased resistance to UV irradiation. Biochem. J. 352, 381-387.
-
(2000)
Biochem. J.
, vol.352
, pp. 381-387
-
-
Nilsson, J.1
Gritli-Linde, A.2
Heby, O.3
-
152
-
-
0032898454
-
Spermine triggers the activation of caspase-3 in a cell-free model of apoptosis
-
Stefanelli, C., Bonavita, F., Stanic, I., Pignatti, C., Flamigni, F., Guarnieri, C. & Caldarera, C.M. (1999) Spermine triggers the activation of caspase-3 in a cell-free model of apoptosis. FEBS Lett. 451, 95-98.
-
(1999)
FEBS Lett.
, vol.451
, pp. 95-98
-
-
Stefanelli, C.1
Bonavita, F.2
Stanic, I.3
Pignatti, C.4
Flamigni, F.5
Guarnieri, C.6
Caldarera, C.M.7
-
153
-
-
0035310347
-
Effect of polyamine depletion on caspase activation: A study with spermine synthase-deficient cells
-
Stefanelli, C., Pignatti, C., Tantini, B., Fattori, M., Stanic, I., Mackintosh, C.A., Flamigni, F., Guarnieri, C., Caldarera, C.M. & Pegg, A.E. (2001) Effect of polyamine depletion on caspase activation: a study with spermine synthase-deficient cells. Biochem. J. 355, 199-206.
-
(2001)
Biochem. J.
, vol.355
, pp. 199-206
-
-
Stefanelli, C.1
Pignatti, C.2
Tantini, B.3
Fattori, M.4
Stanic, I.5
Mackintosh, C.A.6
Flamigni, F.7
Guarnieri, C.8
Caldarera, C.M.9
Pegg, A.E.10
-
154
-
-
0042569018
-
Effect of spermine synthase on the sensitivity of cells to antitumor agents
-
Ikeguchi, Y., Mackintosh, C.A., McCloskey, D.E. & Pegg, A.E. (2003) Effect of spermine synthase on the sensitivity of cells to antitumor agents. Biochem. J. 373, 885-892.
-
(2003)
Biochem. J.
, vol.373
, pp. 885-892
-
-
Ikeguchi, Y.1
Mackintosh, C.A.2
McCloskey, D.E.3
Pegg, A.E.4
-
155
-
-
18344418431
-
Spermine is not essential for growth of Saccharomyces cerevisiae: Identification of the SPE4 gene (spermine synthase) and characterization of a spe4 deletion mutant
-
Hamasaki-Katagiri, N., Katagiri, Y., Tabor, C.W. & Tabor, H. (1998) Spermine is not essential for growth of Saccharomyces cerevisiae: identification of the SPE4 gene (spermine synthase) and characterization of a spe4 deletion mutant. Gene 210, 195-201.
-
(1998)
Gene
, vol.210
, pp. 195-201
-
-
Hamasaki-Katagiri, N.1
Katagiri, Y.2
Tabor, C.W.3
Tabor, H.4
-
156
-
-
0031039128
-
Spermidine biosynthesis in Saccharomyces cerevisae: Polyamine requirement of a null mutant of the SPE3 gene (spermidine synthase)
-
Hamasaki-Katagiri, N., Tabor, C.W. & Tabor, H. (1997) Spermidine biosynthesis in Saccharomyces cerevisae: polyamine requirement of a null mutant of the SPE3 gene (spermidine synthase). Gene 187, 35-43.
-
(1997)
Gene
, vol.187
, pp. 35-43
-
-
Hamasaki-Katagiri, N.1
Tabor, C.W.2
Tabor, H.3
-
157
-
-
0034084960
-
Ornithine decarboxylase transgenic mice as a model for human atrichia with papular lesions
-
Panteleyev, A.A., Christiano, A.M., O'Brien, T.G. & Sundberg, J.P. (2000) Ornithine decarboxylase transgenic mice as a model for human atrichia with papular lesions. Exp. Dermatol 9, 146-151.
-
(2000)
Exp. Dermatol
, vol.9
, pp. 146-151
-
-
Panteleyev, A.A.1
Christiano, A.M.2
O'Brien, T.G.3
Sundberg, J.P.4
-
158
-
-
0022971952
-
Amino acid sequences common to rapidly degraded proteins: The PEST hypothesis
-
Rogers, S., Wells, R. & Rechsteiner, M. (1986) Amino acid sequences common to rapidly degraded proteins: the PEST hypothesis. Science 234, 364-368.
-
(1986)
Science
, vol.234
, pp. 364-368
-
-
Rogers, S.1
Wells, R.2
Rechsteiner, M.3
-
159
-
-
0029131460
-
Point mutation of ornithine decarboxylase gene in human hepatocellular carcinoma 1
-
Tamori, A., Nishiguchi, S., Kuroki, T., Koh, N., Kobayashi, K., Yano, Y. & Otani, S. (1995) Point mutation of ornithine decarboxylase gene in human hepatocellular carcinoma 1. Cell. Res. 55, 3500-3503.
-
(1995)
Cell. Res.
, vol.55
, pp. 3500-3503
-
-
Tamori, A.1
Nishiguchi, S.2
Kuroki, T.3
Koh, N.4
Kobayashi, K.5
Yano, Y.6
Otani, S.7
-
160
-
-
0032085646
-
Point mutations of ornithine decarboxylase gene are an infrequent event in colorectal cancer but a missense mutation was found in a replication error positive patient with hMSH2 germline mutation
-
Maekawa, M., Sugano, K., Kashiwabara, H., Ushiama, M., Fujita, S., Ohkura, H. & Kakizoe, T. (1998) Point mutations of ornithine decarboxylase gene are an infrequent event in colorectal cancer but a missense mutation was found in a replication error positive patient with hMSH2 germline mutation. Jpn. J. Clin. Oncol. 28, 383-387.
-
(1998)
Jpn. J. Clin. Oncol.
, vol.28
, pp. 383-387
-
-
Maekawa, M.1
Sugano, K.2
Kashiwabara, H.3
Ushiama, M.4
Fujita, S.5
Ohkura, H.6
Kakizoe, T.7
-
161
-
-
0037934362
-
Pronounced reduction in adenoma recurrence associated with aspirin use and a polymorphism in the ornithine decarboxylase gene
-
Martinez, M.E., O'Brien, T.G., Fultz, K.E., Babbar, N., Yerushalmi, H., Qu, N., Guo, Y., Boorman, D., Einspahr, J., Alberts, D.S. & Gerner, E.W. (2003) Pronounced reduction in adenoma recurrence associated with aspirin use and a polymorphism in the ornithine decarboxylase gene. Proc. Natl Acad. Sci. USA 100, 7859-7864.
-
(2003)
Proc. Natl Acad. Sci. USA
, vol.100
, pp. 7859-7864
-
-
Martinez, M.E.1
O'Brien, T.G.2
Fultz, K.E.3
Babbar, N.4
Yerushalmi, H.5
Qu, N.6
Guo, Y.7
Boorman, D.8
Einspahr, J.9
Alberts, D.S.10
Gerner, E.W.11
-
162
-
-
0036242706
-
APC-dependent regulation of ornithine decarboxylase in human colon tumor cells
-
Fultz, K.E. & Gerner, E.W. (2002) APC-dependent regulation of ornithine decarboxylase in human colon tumor cells. Mol. Carcinog. 34, 10-18.
-
(2002)
Mol. Carcinog.
, vol.34
, pp. 10-18
-
-
Fultz, K.E.1
Gerner, E.W.2
-
163
-
-
0033693399
-
Functional analysis of human ornithine decarboxylase alleles
-
Guo, Y., Harris, R.B., Rosson, D., Boorman, D. & O'Brien, T.G. (2000) Functional analysis of human ornithine decarboxylase alleles. Cancer Res. 60, 6314-6317.
-
(2000)
Cancer Res.
, vol.60
, pp. 6314-6317
-
-
Guo, Y.1
Harris, R.B.2
Rosson, D.3
Boorman, D.4
O'Brien, T.G.5
-
164
-
-
0025270332
-
Chemoprevention of colon carcinogenesis by concurrent administration of piroxicam, a nonsteroidal anti-inflammatory drug with D,1-α- difluoromethylornithine, an ornithine decarboxylase inhibitor, in diet
-
Reddy, B.S., Nayini, J., Tokumo, K., Rigotty, J., Zang, E. & Kelloff, G. (1990) Chemoprevention of colon carcinogenesis by concurrent administration of piroxicam, a nonsteroidal anti-inflammatory drug with D,1-α- difluoromethylornithine, an ornithine decarboxylase inhibitor, in diet. Cancer Res. 50, 2562-2568.
-
(1990)
Cancer Res.
, vol.50
, pp. 2562-2568
-
-
Reddy, B.S.1
Nayini, J.2
Tokumo, K.3
Rigotty, J.4
Zang, E.5
Kelloff, G.6
-
165
-
-
0025999819
-
Chemoprevention of colon carcinogenesis by dietary administration of piroxicam, a-difluoromethylornithine, 16α-fluoro-5-adrosten-17-one, and ellagic acid individually and in combination
-
Rao, C.V., Tokumo, K., Rigotty, J., Zang, E., Kelloff, G. & Reddy, B.S. (1991) Chemoprevention of colon carcinogenesis by dietary administration of piroxicam, a-difluoromethylornithine, 16α-fluoro-5-adrosten-17-one, and ellagic acid individually and in combination. Cancer Res. 51, 4528-4534.
-
(1991)
Cancer Res.
, vol.51
, pp. 4528-4534
-
-
Rao, C.V.1
Tokumo, K.2
Rigotty, J.3
Zang, E.4
Kelloff, G.5
Reddy, B.S.6
-
166
-
-
0348077408
-
X-linked spermine synthase gene (SMS) defect: The first polyamine deficiency syndrome
-
Cason, A.L., Ikeguchi, Y., Skinner, C., Wood, T.C., Holden, K.R., Lubs, H.A., Martinez, F., Simensen, R.J., Stevenson, R.E., Pegg, A.E. & Schwartz, C.E. (2003) X-linked spermine synthase gene (SMS) defect: the first polyamine deficiency syndrome. Eur. J. Hum. Genet. 11, 937-944.
-
(2003)
Eur. J. Hum. Genet.
, vol.11
, pp. 937-944
-
-
Cason, A.L.1
Ikeguchi, Y.2
Skinner, C.3
Wood, T.C.4
Holden, K.R.5
Lubs, H.A.6
Martinez, F.7
Simensen, R.J.8
Stevenson, R.E.9
Pegg, A.E.10
Schwartz, C.E.11
-
167
-
-
0036765998
-
1-acetyltransferase (SSAT) gene with putrescine accumulation in a patient with a Xp21.1p22.12 duplication and keratosis follicularis spinulosa decalvans (KFSD)
-
1-acetyltransferase (SSAT) gene with putrescine accumulation in a patient with a Xp21.1p22.12 duplication and keratosis follicularis spinulosa decalvans (KFSD). Hum. Genet. 111, 235-241.
-
(2002)
Hum. Genet.
, vol.111
, pp. 235-241
-
-
Gimelli, G.1
Giglio, S.2
Zuffardi, O.3
Alhonen, L.4
Suppola, S.5
Cusano, R.6
Lo Nigro, C.7
Gatti, R.8
Ravazzolo, R.9
Seri, M.10
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