Bioprocess development for the production of mouse-human chimeric anti-epidermal growth factor receptor vIII antibody C12 by suspension culture of recombinant Chinese hamster ovary cells

Cytotechnology

Volumn 63, Issue 3, 2011, Pages 247-258

  Hu, Suwen ^a   Deng, Lei ^a   Wang, Huamao ^b   Zhuang, Yingping ^a   Chu, Ju ^a   Zhang, Siliang ^a   Li, Zhonghai ^b   Guo, Meijin ^a  

^a EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b SHANGHAI JIAO TONG UNIVERSITY   (China)

Author keywords

Balanced amino acid feed; Mouse human chimeric anti EGFRvIII antibody; Perfusion culture; Recombinant CHO C12 cells

Indexed keywords

AMINO ACID; ANTIBODY; ASPARAGINE; ASPARTIC ACID; EPIDERMAL GROWTH FACTOR RECEPTOR VIII ANTIBODY C12; GLUCOSE; GLUTAMIC ACID; GLUTAMINE; ISOLEUCINE; LEUCINE; LYSINE; SERINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL CELL CULTURE; ANTIBODY PRODUCTION; ARTICLE; BACTERIUM CULTURE; BIOPROCESS; BIOREACTOR; CELL GROWTH; CELL VIABILITY; CULTURE MEDIUM; DENSITY; FEMALE; INOCULATION; NONHUMAN; OVARY CELL CULTURE; SUSPENSION CELL CULTURE;

CRICETULUS GRISEUS;

EID: 79955890559     PISSN: 09209069     EISSN: 15730778     Source Type: Journal    
DOI: 10.1007/s10616-011-9336-y     Document Type: Article

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