Overexpression of the antioxidant enzyme catalase does not interfere with the glucose responsiveness of insulin-secreting INS-1E cells and rat islets

Diabetologia

Volumn 56, Issue 4, 2013, Pages 774-782

  Lortz, S ^a   Gurgul Convey, E ^a   Naujok, O ^a   Lenzen, S ^a  

^a HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

Catalase; Glucose stimulated insulin secretion; Insulin secreting cells; Pro inflammatory cytokines; Reactive oxygen species

Indexed keywords

ANTIOXIDANT; CASPASE 3; CATALASE; CYTOKINE; GLUCOSE; HYDROGEN PEROXIDE; INSULIN; REACTIVE OXYGEN METABOLITE; UNCOUPLING PROTEIN 2;

ANIMAL CELL; ARTICLE; CELL VIABILITY; CYTOSOL; ENZYME ACTIVATION; GENE OVEREXPRESSION; GENETIC CODE; HYPOXIA; INSULIN RELEASE; MALE; MITOCHONDRIAL MEMBRANE POTENTIAL; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION;

2,4-DINITROPHENOL; ANIMALS; BLOOD GLUCOSE; CATALASE; CYTOKINES; CYTOSOL; FLOW CYTOMETRY; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GLUCOSE; HYDROGEN PEROXIDE; INSULIN; ION CHANNELS; ISLETS OF LANGERHANS; MALE; MEMBRANE POTENTIALS; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; OXIDATIVE STRESS; RATS; RATS, INBRED LEW; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION;

EID: 84876484085     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-012-2823-7     Document Type: Article

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