β-cell uncoupling protein 2 regulates reactive oxygen species production, which influences both insulin and glucagon secretion

Diabetes

Volumn 60, Issue 11, 2011, Pages 2710-2719

  Robson Doucette, Christine A ^a   Sultan, Sobia ^a   Allister, Emma M ^a   Wikstrom, Jakob D ^b,c   Koshkin, Vasilij ^a   Bhatacharjee, Alpana ^a   Prentice, Kacey J ^a   Sereda, Samuel B ^b   Shirihai, Orian S ^b   Wheeler, Michael B ^a  

^a UNIVERSITY OF TORONTO   (Canada)

^b BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c STOCKHOLM UNIVERSITY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; GLUCAGON; GLUCOSE; INSULIN; REACTIVE OXYGEN METABOLITE; UNCOUPLING PROTEIN 2;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL LEVEL; CELL STRUCTURE; CONTROLLED STUDY; GENE EXPRESSION; GLUCAGON RELEASE; GLUCOSE INTOLERANCE; GLUCOSE TOLERANCE; HUMAN; HUMAN TISSUE; HYPERPOLARIZATION; INSULIN RELEASE; INSULIN TOLERANCE TEST; MALE; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRIAL RESPIRATION; MOUSE; NONHUMAN; ORAL GLUCOSE TOLERANCE TEST; PANCREAS ISLET ALPHA CELL; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN FUNCTION; REGULATORY MECHANISM;

ANIMALS; GENES, REPORTER; GLUCAGON; GLUCAGON-SECRETING CELLS; GLUCOSE INTOLERANCE; HUMANS; HYPERGLYCEMIA; INSULIN; INSULIN-SECRETING CELLS; ION CHANNELS; ISLETS OF LANGERHANS; MALE; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICE; MICE, 129 STRAIN; MICE, INBRED C57BL; MICE, KNOCKOUT; MITOCHONDRIAL PROTEINS; ORGAN SPECIFICITY; PROMOTER REGIONS, GENETIC; RATS; REACTIVE OXYGEN SPECIES; TISSUE CULTURE TECHNIQUES;

EID: 80755168930     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db11-0132     Document Type: Article

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