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Volumn 139, Issue 1, 2013, Pages 11-18

The role of interferon-β in the treatment of multiple sclerosis and experimental autoimmune encephalomyelitis - in the perspective of inflammasomes

Author keywords

Cell migration; Chemotaxis; Experimental autoimmune encephalomyelitis; Interferon ; Multiple sclerosis; NLRP3 inflammasome

Indexed keywords

ADENOSINE TRIPHOSPHATE; AMYLOID BETA PROTEIN; BETA INTERFERON; CASPASE 11; CATHEPSIN B; CHEMOKINE RECEPTOR CXCR6; CHOLERA TOXIN B SUBUNIT; CRYOPYRIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INFLAMMASOME; INTERFERON; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 10; INTERLEUKIN 17; INTERLEUKIN 18; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 2; MONOCYTE CHEMOTACTIC PROTEIN 3; NUCLEOTIDE BINDING OLIGOMERIZATION DOMAIN LIKE RECEPTOR; P2X7R ANTAGONISTS; PATTERN RECOGNITION RECEPTOR; PURINE; PURINERGIC P2X RECEPTOR ANTAGONIST; PURINERGIC P2X7 RECEPTOR; SUPPRESSOR OF CYTOKINE SIGNALING 1; UNCLASSIFIED DRUG; UNINDEXED DRUG; URIC ACID; VERY LATE ACTIVATION ANTIGEN 4;

EID: 84876049501     PISSN: 00192805     EISSN: 13652567     Source Type: Journal    
DOI: 10.1111/imm.12081     Document Type: Article
Times cited : (77)

References (84)
  • 3
    • 16244362671 scopus 로고    scopus 로고
    • Apoptosis, pyroptosis, and necrosis: mechanistic description of dead and dying eukaryotic cells
    • Fink SL, Cookson BT. Apoptosis, pyroptosis, and necrosis: mechanistic description of dead and dying eukaryotic cells. Infect Immun 2005; 73:1907-16.
    • (2005) Infect Immun , vol.73 , pp. 1907-1916
    • Fink, S.L.1    Cookson, B.T.2
  • 4
    • 79952159132 scopus 로고    scopus 로고
    • Emerging inflammasome effector mechanisms
    • Lamkanfi, M Emerging inflammasome effector mechanisms. Nat Rev Immunol 2011; 11:213-20.
    • (2011) Nat Rev Immunol , vol.11 , pp. 213-220
    • Lamkanfi, M.1
  • 5
    • 32944470765 scopus 로고    scopus 로고
    • Cryopyrin activates the inflammasome in response to toxins and ATP
    • Mariathasan S, Weiss DS, Newton K et al. Cryopyrin activates the inflammasome in response to toxins and ATP. Nature 2006; 440:228-32.
    • (2006) Nature , vol.440 , pp. 228-232
    • Mariathasan, S.1    Weiss, D.S.2    Newton, K.3
  • 6
    • 67349271142 scopus 로고    scopus 로고
    • Syk kinase signalling couples to the Nlrp3 inflammasome for anti-fungal host defence
    • Gross O, Poeck H, Bscheider M et al. Syk kinase signalling couples to the Nlrp3 inflammasome for anti-fungal host defence. Nature 2009; 459:433-6.
    • (2009) Nature , vol.459 , pp. 433-436
    • Gross, O.1    Poeck, H.2    Bscheider, M.3
  • 7
    • 32944468985 scopus 로고    scopus 로고
    • Gout-associated uric acid crystals activate the NALP3 inflammasome
    • Martinon F, Petrilli V, Mayor A, Tardivel A, Tschopp J. Gout-associated uric acid crystals activate the NALP3 inflammasome. Nature 2006; 440:237-41.
    • (2006) Nature , vol.440 , pp. 237-241
    • Martinon, F.1    Petrilli, V.2    Mayor, A.3    Tardivel, A.4    Tschopp, J.5
  • 8
    • 47849085872 scopus 로고    scopus 로고
    • The NALP3 inflammasome is involved in the innate immune response to amyloid-β
    • Halle A, Hornung V, Petzold GC et al. The NALP3 inflammasome is involved in the innate immune response to amyloid-β. Nat Immunol 2008; 9:857-65.
    • (2008) Nat Immunol , vol.9 , pp. 857-865
    • Halle, A.1    Hornung, V.2    Petzold, G.C.3
  • 10
    • 47849097202 scopus 로고    scopus 로고
    • Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization
    • Hornung V, Bauernfeind F, Halle A et al. Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization. Nat Immunol 2008; 9:847-56.
    • (2008) Nat Immunol , vol.9 , pp. 847-856
    • Hornung, V.1    Bauernfeind, F.2    Halle, A.3
  • 11
    • 77649179433 scopus 로고    scopus 로고
    • NLRP3 inflammasome activation: the convergence of multiple signalling pathways on ROS production?
    • Tschopp J, Schroder K. NLRP3 inflammasome activation: the convergence of multiple signalling pathways on ROS production? Nat Rev Immunol 2010; 10:210-5.
    • (2010) Nat Rev Immunol , vol.10 , pp. 210-215
    • Tschopp, J.1    Schroder, K.2
  • 12
    • 77950362382 scopus 로고    scopus 로고
    • The inflammasomes
    • Schroder K, Tschopp J. The inflammasomes. Cell 2010; 140:821-32.
    • (2010) Cell , vol.140 , pp. 821-832
    • Schroder, K.1    Tschopp, J.2
  • 13
    • 1642285783 scopus 로고    scopus 로고
    • NALP3 forms an IL-1β-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder
    • Agostini L, Martinon F, Burns K, McDermott MF, Hawkins PN, Tschopp J. NALP3 forms an IL-1β-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder. Immunity 2004; 20:319-25.
    • (2004) Immunity , vol.20 , pp. 319-325
    • Agostini, L.1    Martinon, F.2    Burns, K.3    McDermott, M.F.4    Hawkins, P.N.5    Tschopp, J.6
  • 14
    • 64049111768 scopus 로고    scopus 로고
    • The NLRP3 inflammasome mediates in vivo innate immunity to influenza A virus through recognition of viral RNA
    • Allen IC, Scull MA, Moore CB et al. The NLRP3 inflammasome mediates in vivo innate immunity to influenza A virus through recognition of viral RNA. Immunity 2009; 30:556-65.
    • (2009) Immunity , vol.30 , pp. 556-565
    • Allen, I.C.1    Scull, M.A.2    Moore, C.B.3
  • 15
    • 0037144586 scopus 로고    scopus 로고
    • A novel PAAD-containing protein that modulates NF-κB induction by cytokines tumor necrosis factor-α and interleukin-1β
    • Fiorentino L, Stehlik C, Oliveira V, Ariza ME, Godzik A, Reed JC. A novel PAAD-containing protein that modulates NF-κB induction by cytokines tumor necrosis factor-α and interleukin-1β. J Biol Chem 2002; 277:35333-40.
    • (2002) J Biol Chem , vol.277 , pp. 35333-35340
    • Fiorentino, L.1    Stehlik, C.2    Oliveira, V.3    Ariza, M.E.4    Godzik, A.5    Reed, J.C.6
  • 17
    • 84861460062 scopus 로고    scopus 로고
    • NLRP12 suppresses colon inflammation and tumorigenesis through the negative regulation of noncanonical NF-κB signaling
    • Allen IC, Wilson JE, Schneider M et al. NLRP12 suppresses colon inflammation and tumorigenesis through the negative regulation of noncanonical NF-κB signaling. Immunity 2012; 36:742-54.
    • (2012) Immunity , vol.36 , pp. 742-754
    • Allen, I.C.1    Wilson, J.E.2    Schneider, M.3
  • 18
    • 80455176839 scopus 로고    scopus 로고
    • Non-canonical inflammasome activation targets caspase-11
    • Kayagaki N, Warming S, Lamkanfi M et al. Non-canonical inflammasome activation targets caspase-11. Nature 2011; 479:117-21.
    • (2011) Nature , vol.479 , pp. 117-121
    • Kayagaki, N.1    Warming, S.2    Lamkanfi, M.3
  • 19
    • 10444241090 scopus 로고    scopus 로고
    • Clinical and genetic heterogeneity among Spanish patients with recurrent autoinflammatory syndromes associated with the CIAS1/PYPAF1/NALP3 gene
    • Arostegui JI, Aldea A, Modesto C et al. Clinical and genetic heterogeneity among Spanish patients with recurrent autoinflammatory syndromes associated with the CIAS1/PYPAF1/NALP3 gene. Arthritis Rheum 2004; 50:4045-50.
    • (2004) Arthritis Rheum , vol.50 , pp. 4045-4050
    • Arostegui, J.I.1    Aldea, A.2    Modesto, C.3
  • 20
    • 0035179970 scopus 로고    scopus 로고
    • Mutation of a new gene encoding a putative pyrin-like protein causes familial cold autoinflammatory syndrome and Muckle-Wells syndrome
    • Hoffman HM, Mueller JL, Broide DH, Wanderer AA, Kolodner RD. Mutation of a new gene encoding a putative pyrin-like protein causes familial cold autoinflammatory syndrome and Muckle-Wells syndrome. Nat Genet 2001; 29:301-5.
    • (2001) Nat Genet , vol.29 , pp. 301-305
    • Hoffman, H.M.1    Mueller, J.L.2    Broide, D.H.3    Wanderer, A.A.4    Kolodner, R.D.5
  • 21
    • 18344385660 scopus 로고    scopus 로고
    • New mutations of CIAS1 that are responsible for Muckle-Wells syndrome and familial cold urticaria: a novel mutation underlies both syndromes
    • Dode C, Le Du N, Cuisset L et al. New mutations of CIAS1 that are responsible for Muckle-Wells syndrome and familial cold urticaria: a novel mutation underlies both syndromes. Am J Hum Genet 2002; 70:1498-506.
    • (2002) Am J Hum Genet , vol.70 , pp. 1498-1506
    • Dode, C.1    Le Du, N.2    Cuisset, L.3
  • 22
    • 0036302235 scopus 로고    scopus 로고
    • Chronic infantile neurological cutaneous and articular syndrome is caused by mutations in CIAS1, a gene highly expressed in polymorphonuclear cells and chondrocytes
    • Feldmann J, Prieur AM, Quartier P et al. Chronic infantile neurological cutaneous and articular syndrome is caused by mutations in CIAS1, a gene highly expressed in polymorphonuclear cells and chondrocytes. Am J Hum Genet 2002; 71:198-203.
    • (2002) Am J Hum Genet , vol.71 , pp. 198-203
    • Feldmann, J.1    Prieur, A.M.2    Quartier, P.3
  • 23
    • 66949175347 scopus 로고    scopus 로고
    • A mutation in the Nlrp3 gene causing inflammasome hyperactivation potentiates Th17 cell-dominant immune responses
    • Meng G, Zhang F, Fuss I, Kitani A, Strober W. A mutation in the Nlrp3 gene causing inflammasome hyperactivation potentiates Th17 cell-dominant immune responses. Immunity 2009; 30:860-74.
    • (2009) Immunity , vol.30 , pp. 860-874
    • Meng, G.1    Zhang, F.2    Fuss, I.3    Kitani, A.4    Strober, W.5
  • 25
    • 78149442887 scopus 로고    scopus 로고
    • Two SNPs in NLRP3 gene are involved in the predisposition to type-1 diabetes and celiac disease in a pediatric population from northeast Brazil
    • Pontillo A, Brandao L, Guimaraes R, Segat L, Araujo J, Crovella S. Two SNPs in NLRP3 gene are involved in the predisposition to type-1 diabetes and celiac disease in a pediatric population from northeast Brazil. Autoimmunity 2010; 43:583-9.
    • (2010) Autoimmunity , vol.43 , pp. 583-589
    • Pontillo, A.1    Brandao, L.2    Guimaraes, R.3    Segat, L.4    Araujo, J.5    Crovella, S.6
  • 26
    • 70349675610 scopus 로고    scopus 로고
    • Genetic variation in the familial Mediterranean fever gene (MEFV) and risk for Crohn's disease and ulcerative colitis
    • Villani AC, Lemire M, Louis E et al. Genetic variation in the familial Mediterranean fever gene (MEFV) and risk for Crohn's disease and ulcerative colitis. PLoS ONE 2009; 4:e7154.
    • (2009) PLoS ONE , vol.4
    • Villani, A.C.1    Lemire, M.2    Louis, E.3
  • 27
    • 74849111621 scopus 로고    scopus 로고
    • Identification of intergenic trans-regulatory RNAs containing a disease-linked SNP sequence and targeting cell cycle progression/differentiation pathways in multiple common human disorders
    • Glinskii AB, Ma J, Ma S, Grant D, Lim CU, Sell S, Glinsky GV. Identification of intergenic trans-regulatory RNAs containing a disease-linked SNP sequence and targeting cell cycle progression/differentiation pathways in multiple common human disorders. Cell Cycle 2009; 8:3925-42.
    • (2009) Cell Cycle , vol.8 , pp. 3925-3942
    • Glinskii, A.B.1    Ma, J.2    Ma, S.3    Grant, D.4    Lim, C.U.5    Sell, S.6    Glinsky, G.V.7
  • 28
    • 84863253461 scopus 로고    scopus 로고
    • NLRP1 gene polymorphism influences gene transcription and is a risk factor for rheumatoid arthritis in Han Chinese
    • Sui J, Li H, Fang Y et al. NLRP1 gene polymorphism influences gene transcription and is a risk factor for rheumatoid arthritis in Han Chinese. Arthritis Rheum 2012; 64:647-54.
    • (2012) Arthritis Rheum , vol.64 , pp. 647-654
    • Sui, J.1    Li, H.2    Fang, Y.3
  • 29
    • 77955853897 scopus 로고    scopus 로고
    • Systemic lupus erythematosus and increased risk to develop B cell malignancies: role of the p200-family proteins
    • Veeranki S, Choubey D. Systemic lupus erythematosus and increased risk to develop B cell malignancies: role of the p200-family proteins. Immunol Lett 2010; 133:1-5.
    • (2010) Immunol Lett , vol.133 , pp. 1-5
    • Veeranki, S.1    Choubey, D.2
  • 30
    • 0032702860 scopus 로고    scopus 로고
    • Peripheral levels of caspase-1 mRNA correlate with disease activity in patients with multiple sclerosis; a preliminary study
    • Furlan R, Filippi M, Bergami A et al. Peripheral levels of caspase-1 mRNA correlate with disease activity in patients with multiple sclerosis; a preliminary study. J Neurol Neurosurg Psychiatry 1999; 67:785-8.
    • (1999) J Neurol Neurosurg Psychiatry , vol.67 , pp. 785-788
    • Furlan, R.1    Filippi, M.2    Bergami, A.3
  • 32
    • 4444254434 scopus 로고    scopus 로고
    • Increased expression of caspase-1 and interleukin-18 in peripheral blood mononuclear cells in patients with multiple sclerosis
    • Huang WX, Huang P, Hillert J. Increased expression of caspase-1 and interleukin-18 in peripheral blood mononuclear cells in patients with multiple sclerosis. Mult Scler 2004; 10:482-7.
    • (2004) Mult Scler , vol.10 , pp. 482-487
    • Huang, W.X.1    Huang, P.2    Hillert, J.3
  • 33
    • 0035999548 scopus 로고    scopus 로고
    • Production of IL-1β and IL-1Ra as risk factors for susceptibility and progression of relapse-onset multiple sclerosis
    • de Jong BA, Huizinga TW, Bollen EL et al. Production of IL-1β and IL-1Ra as risk factors for susceptibility and progression of relapse-onset multiple sclerosis. J Neuroimmunol 2002; 126:172-9.
    • (2002) J Neuroimmunol , vol.126 , pp. 172-179
    • de Jong, B.A.1    Huizinga, T.W.2    Bollen, E.L.3
  • 34
    • 67349252457 scopus 로고    scopus 로고
    • Increase of uric acid and purine compounds in biological fluids of multiple sclerosis patients
    • Amorini AM, Petzold A, Tavazzi B et al. Increase of uric acid and purine compounds in biological fluids of multiple sclerosis patients. Clin Biochem 2009; 42:1001-6.
    • (2009) Clin Biochem , vol.42 , pp. 1001-1006
    • Amorini, A.M.1    Petzold, A.2    Tavazzi, B.3
  • 35
    • 84863252356 scopus 로고    scopus 로고
    • Serum uric acid levels in patients with multiple sclerosis: a meta-analysis
    • Liu B, Shen Y, Xiao K, Tang Y, Cen L, Wei J. Serum uric acid levels in patients with multiple sclerosis: a meta-analysis. Neurol Res 2012; 34:163-71.
    • (2012) Neurol Res , vol.34 , pp. 163-171
    • Liu, B.1    Shen, Y.2    Xiao, K.3    Tang, Y.4    Cen, L.5    Wei, J.6
  • 36
    • 0028298132 scopus 로고
    • Increased cathepsin B activity in peripheral blood mononuclear cells of multiple sclerosis patients
    • Bever CT Jr, Panitch HS, Johnson KP. Increased cathepsin B activity in peripheral blood mononuclear cells of multiple sclerosis patients. Neurology 1994; 44:745-8.
    • (1994) Neurology , vol.44 , pp. 745-748
    • Bever Jr., C.T.1    Panitch, H.S.2    Johnson, K.P.3
  • 37
    • 0029004145 scopus 로고
    • Increased cathepsin B activity in multiple sclerosis brain
    • Bever CT Jr, Garver DW. Increased cathepsin B activity in multiple sclerosis brain. J Neurol Sci 1995; 131:71-3.
    • (1995) J Neurol Sci , vol.131 , pp. 71-73
    • Bever Jr., C.T.1    Garver, D.W.2
  • 38
    • 34548398189 scopus 로고    scopus 로고
    • P2X(7) receptor blockade prevents ATP excitotoxicity in oligodendrocytes and ameliorates experimental autoimmune encephalomyelitis
    • Matute C, Torre I, Perez-Cerda F et al. P2X(7) receptor blockade prevents ATP excitotoxicity in oligodendrocytes and ameliorates experimental autoimmune encephalomyelitis. J Neurosci 2007; 27:9525-33.
    • (2007) J Neurosci , vol.27 , pp. 9525-9533
    • Matute, C.1    Torre, I.2    Perez-Cerda, F.3
  • 41
    • 77955475968 scopus 로고    scopus 로고
    • NLRP3 plays a critical role in the development of experimental autoimmune encephalomyelitis by mediating Th1 and Th17 responses
    • Gris D, Ye Z, Iocca HA et al. NLRP3 plays a critical role in the development of experimental autoimmune encephalomyelitis by mediating Th1 and Th17 responses. J Immunol 2010; 185:974-81.
    • (2010) J Immunol , vol.185 , pp. 974-981
    • Gris, D.1    Ye, Z.2    Iocca, H.A.3
  • 42
    • 78649396261 scopus 로고    scopus 로고
    • The inflammasome sensor, NLRP3, regulates CNS inflammation and demyelination via caspase-1 and interleukin-18
    • Jha S, Srivastava SY, Brickey WJ et al. The inflammasome sensor, NLRP3, regulates CNS inflammation and demyelination via caspase-1 and interleukin-18. J Neurosci 2010; 30:15811-20.
    • (2010) J Neurosci , vol.30 , pp. 15811-15820
    • Jha, S.1    Srivastava, S.Y.2    Brickey, W.J.3
  • 43
    • 84862988248 scopus 로고    scopus 로고
    • NLRP3 inflammasome induces chemotactic immune cell migration to the CNS in experimental autoimmune encephalomyelitis
    • Inoue M, Williams KL, Gunn MD, Shinohara ML. NLRP3 inflammasome induces chemotactic immune cell migration to the CNS in experimental autoimmune encephalomyelitis. Proc Natl Acad Sci USA 2012; 109:10480-5.
    • (2012) Proc Natl Acad Sci USA , vol.109 , pp. 10480-10485
    • Inoue, M.1    Williams, K.L.2    Gunn, M.D.3    Shinohara, M.L.4
  • 44
  • 45
    • 0033198269 scopus 로고    scopus 로고
    • Caspase-1 regulates the inflammatory process leading to autoimmune demyelination
    • Furlan R, Martino G, Galbiati F et al. Caspase-1 regulates the inflammatory process leading to autoimmune demyelination. J Immunol 1999; 163:2403-9.
    • (1999) J Immunol , vol.163 , pp. 2403-2409
    • Furlan, R.1    Martino, G.2    Galbiati, F.3
  • 46
    • 0036840008 scopus 로고    scopus 로고
    • A role for caspase-1 and -3 in the pathology of experimental allergic encephalomyelitis: inflammation versus degeneration
    • Ahmed Z, Doward AI, Pryce G et al. A role for caspase-1 and -3 in the pathology of experimental allergic encephalomyelitis: inflammation versus degeneration. Am J Pathol 2002; 161:1577-86.
    • (2002) Am J Pathol , vol.161 , pp. 1577-1586
    • Ahmed, Z.1    Doward, A.I.2    Pryce, G.3
  • 47
    • 72449132320 scopus 로고    scopus 로고
    • Initiation and progression of axonopathy in experimental autoimmune encephalomyelitis
    • Soulika AM, Lee E, McCauley E, Miers L, Bannerman P, Pleasure D. Initiation and progression of axonopathy in experimental autoimmune encephalomyelitis. J Neurosci 2009; 29:14965-79.
    • (2009) J Neurosci , vol.29 , pp. 14965-14979
    • Soulika, A.M.1    Lee, E.2    McCauley, E.3    Miers, L.4    Bannerman, P.5    Pleasure, D.6
  • 48
    • 84455205524 scopus 로고    scopus 로고
    • The Hedgehog pathway promotes blood-brain barrier integrity and CNS immune quiescence
    • Alvarez JI, Dodelet-Devillers A, Kebir H et al. The Hedgehog pathway promotes blood-brain barrier integrity and CNS immune quiescence. Science 2011; 334:1727-31.
    • (2011) Science , vol.334 , pp. 1727-1731
    • Alvarez, J.I.1    Dodelet-Devillers, A.2    Kebir, H.3
  • 49
    • 7244251521 scopus 로고    scopus 로고
    • Reversible demyelination, blood-brain barrier breakdown, and pronounced neutrophil recruitment induced by chronic IL-1 expression in the brain
    • Ferrari CC, Depino AM, Prada F et al. Reversible demyelination, blood-brain barrier breakdown, and pronounced neutrophil recruitment induced by chronic IL-1 expression in the brain. Am J Pathol 2004; 165:1827-37.
    • (2004) Am J Pathol , vol.165 , pp. 1827-1837
    • Ferrari, C.C.1    Depino, A.M.2    Prada, F.3
  • 50
    • 33745873727 scopus 로고    scopus 로고
    • A crucial role for interleukin (IL)-1 in the induction of IL-17-producing T cells that mediate autoimmune encephalomyelitis
    • Sutton C, Brereton C, Keogh B, Mills KH, Lavelle EC. A crucial role for interleukin (IL)-1 in the induction of IL-17-producing T cells that mediate autoimmune encephalomyelitis. J Exp Med 2006; 203:1685-91.
    • (2006) J Exp Med , vol.203 , pp. 1685-1691
    • Sutton, C.1    Brereton, C.2    Keogh, B.3    Mills, K.H.4    Lavelle, E.C.5
  • 51
    • 68649088121 scopus 로고    scopus 로고
    • Interleukin-1 and IL-23 induce innate IL-17 production from γδ T cells, amplifying Th17 responses and autoimmunity
    • Sutton CE, Lalor SJ, Sweeney CM, Brereton CF, Lavelle EC, Mills KH. Interleukin-1 and IL-23 induce innate IL-17 production from γδ T cells, amplifying Th17 responses and autoimmunity. Immunity 2009; 31:331-41.
    • (2009) Immunity , vol.31 , pp. 331-341
    • Sutton, C.E.1    Lalor, S.J.2    Sweeney, C.M.3    Brereton, C.F.4    Lavelle, E.C.5    Mills, K.H.6
  • 52
    • 79956187649 scopus 로고    scopus 로고
    • Caspase-1-processed cytokines IL-1β and IL-18 promote IL-17 production by γδ and CD4 T cells that mediate autoimmunity
    • Lalor SJ, Dungan LS, Sutton CE, Basdeo SA, Fletcher JM, Mills KH. Caspase-1-processed cytokines IL-1β and IL-18 promote IL-17 production by γδ and CD4 T cells that mediate autoimmunity. J Immunol 2011; 186:5738-48.
    • (2011) J Immunol , vol.186 , pp. 5738-5748
    • Lalor, S.J.1    Dungan, L.S.2    Sutton, C.E.3    Basdeo, S.A.4    Fletcher, J.M.5    Mills, K.H.6
  • 53
    • 0034176818 scopus 로고    scopus 로고
    • Reduced chemokine and chemokine receptor expression in spinal cords of TCR BV8S2 transgenic mice protected against experimental autoimmune encephalomyelitis with BV8S2 protein
    • Matejuk A, Vandenbark AA, Burrows GG, Bebo BF Jr, Offner H. Reduced chemokine and chemokine receptor expression in spinal cords of TCR BV8S2 transgenic mice protected against experimental autoimmune encephalomyelitis with BV8S2 protein. J Immunol 2000; 164:3924-31.
    • (2000) J Immunol , vol.164 , pp. 3924-3931
    • Matejuk, A.1    Vandenbark, A.A.2    Burrows, G.G.3    Bebo Jr., B.F.4    Offner, H.5
  • 54
    • 0034596949 scopus 로고    scopus 로고
    • Resistance to experimental autoimmune encephalomyelitis in mice lacking the CC chemokine receptor (CCR)2
    • Izikson L, Klein RS, Charo IF, Weiner HL, Luster AD. Resistance to experimental autoimmune encephalomyelitis in mice lacking the CC chemokine receptor (CCR)2. J Exp Med 2000; 192:1075-80.
    • (2000) J Exp Med , vol.192 , pp. 1075-1080
    • Izikson, L.1    Klein, R.S.2    Charo, I.F.3    Weiner, H.L.4    Luster, A.D.5
  • 55
    • 71749097979 scopus 로고    scopus 로고
    • Two-photon laser scanning microscopy imaging of intact spinal cord and cerebral cortex reveals requirement for CXCR6 and neuroinflammation in immune cell infiltration of cortical injury sites
    • Kim JV, Jiang N, Tadokoro CE, Liu L, Ransohoff RM, Lafaille JJ, Dustin ML. Two-photon laser scanning microscopy imaging of intact spinal cord and cerebral cortex reveals requirement for CXCR6 and neuroinflammation in immune cell infiltration of cortical injury sites. J Immunol Methods 2010; 352:89-100.
    • (2010) J Immunol Methods , vol.352 , pp. 89-100
    • Kim, J.V.1    Jiang, N.2    Tadokoro, C.E.3    Liu, L.4    Ransohoff, R.M.5    Lafaille, J.J.6    Dustin, M.L.7
  • 56
    • 0035941106 scopus 로고    scopus 로고
    • The influence of the proinflammatory cytokine, osteopontin, on autoimmune demyelinating disease
    • Chabas D, Baranzini SE, Mitchell D et al. The influence of the proinflammatory cytokine, osteopontin, on autoimmune demyelinating disease. Science 2001; 294:1731-5.
    • (2001) Science , vol.294 , pp. 1731-1735
    • Chabas, D.1    Baranzini, S.E.2    Mitchell, D.3
  • 57
    • 18544404188 scopus 로고    scopus 로고
    • Distinct chemokine receptor and cytokine expression profile in secondary progressive MS
    • Sorensen TL, Sellebjerg F. Distinct chemokine receptor and cytokine expression profile in secondary progressive MS. Neurology 2001; 57:1371-6.
    • (2001) Neurology , vol.57 , pp. 1371-1376
    • Sorensen, T.L.1    Sellebjerg, F.2
  • 58
    • 0035283409 scopus 로고    scopus 로고
    • Chemokine receptor expression on T cells in blood and cerebrospinal fluid at relapse and remission of multiple sclerosis: imbalance of Th1/Th2-associated chemokine signaling
    • Misu T, Onodera H, Fujihara K et al. Chemokine receptor expression on T cells in blood and cerebrospinal fluid at relapse and remission of multiple sclerosis: imbalance of Th1/Th2-associated chemokine signaling. J Neuroimmunol 2001; 114:207-12.
    • (2001) J Neuroimmunol , vol.114 , pp. 207-212
    • Misu, T.1    Onodera, H.2    Fujihara, K.3
  • 60
    • 0036499086 scopus 로고    scopus 로고
    • Cutting edge: attenuated experimental autoimmune encephalomyelitis in eta-1/osteopontin-deficient mice
    • Jansson M, Panoutsakopoulou V, Baker J, Klein L, Cantor H. Cutting edge: attenuated experimental autoimmune encephalomyelitis in eta-1/osteopontin-deficient mice. J Immunol 2002; 168:2096-9.
    • (2002) J Immunol , vol.168 , pp. 2096-2099
    • Jansson, M.1    Panoutsakopoulou, V.2    Baker, J.3    Klein, L.4    Cantor, H.5
  • 61
    • 33846998653 scopus 로고    scopus 로고
    • Osteopontin-induced relapse and progression of autoimmune brain disease through enhanced survival of activated T cells
    • Hur EM, Youssef S, Haws ME, Zhang SY, Sobel RA, Steinman L. Osteopontin-induced relapse and progression of autoimmune brain disease through enhanced survival of activated T cells. Nat Immunol 2007; 8:74-83.
    • (2007) Nat Immunol , vol.8 , pp. 74-83
    • Hur, E.M.1    Youssef, S.2    Haws, M.E.3    Zhang, S.Y.4    Sobel, R.A.5    Steinman, L.6
  • 62
    • 44449146212 scopus 로고    scopus 로고
    • Engagement of the type I interferon receptor on dendritic cells inhibits T helper 17 cell development: role of intracellular osteopontin
    • Shinohara ML, Kim JH, Garcia VA, Cantor H. Engagement of the type I interferon receptor on dendritic cells inhibits T helper 17 cell development: role of intracellular osteopontin. Immunity 2008; 29:68-78.
    • (2008) Immunity , vol.29 , pp. 68-78
    • Shinohara, M.L.1    Kim, J.H.2    Garcia, V.A.3    Cantor, H.4
  • 63
    • 79951740151 scopus 로고    scopus 로고
    • Type I interferon inhibits interleukin-1 production and inflammasome activation
    • Guarda G, Braun M, Staehli F et al. Type I interferon inhibits interleukin-1 production and inflammasome activation. Immunity 2011; 34:213-23.
    • (2011) Immunity , vol.34 , pp. 213-223
    • Guarda, G.1    Braun, M.2    Staehli, F.3
  • 64
    • 84869785875 scopus 로고    scopus 로고
    • Cutting edge: nitric oxide inhibits the NLRP3 inflammasome
    • Hernandez-Cuellar E, Tsuchiya K, Hara H et al. Cutting edge: nitric oxide inhibits the NLRP3 inflammasome. J Immunol 2012; 189:5113-7.
    • (2012) J Immunol , vol.189 , pp. 5113-5117
    • Hernandez-Cuellar, E.1    Tsuchiya, K.2    Hara, H.3
  • 65
    • 43049101640 scopus 로고    scopus 로고
    • The type I IFN induction pathway constrains Th17-mediated autoimmune inflammation in mice
    • Guo B, Chang EY, Cheng G. The type I IFN induction pathway constrains Th17-mediated autoimmune inflammation in mice. J Clin Invest 2008; 118:1680-90.
    • (2008) J Clin Invest , vol.118 , pp. 1680-1690
    • Guo, B.1    Chang, E.Y.2    Cheng, G.3
  • 66
    • 43049177588 scopus 로고    scopus 로고
    • Distinct and nonredundant in vivo functions of IFNAR on myeloid cells limit autoimmunity in the central nervous system
    • Prinz M, Schmidt H, Mildner A et al. Distinct and nonredundant in vivo functions of IFNAR on myeloid cells limit autoimmunity in the central nervous system. Immunity 2008; 28:675-86.
    • (2008) Immunity , vol.28 , pp. 675-686
    • Prinz, M.1    Schmidt, H.2    Mildner, A.3
  • 67
    • 77954041785 scopus 로고    scopus 로고
    • Interferon-β inhibits Th17 cell differentiation in patients with multiple sclerosis
    • Ramgolam VS, Markovic-Plese S. Interferon-β inhibits Th17 cell differentiation in patients with multiple sclerosis. Endocr Metab Immune Disord Drug Targets 2010; 10:161-7.
    • (2010) Endocr Metab Immune Disord Drug Targets , vol.10 , pp. 161-167
    • Ramgolam, V.S.1    Markovic-Plese, S.2
  • 69
    • 49449097216 scopus 로고    scopus 로고
    • + cells through the boost of the Th2 phenotype, the inhibition of Th17 response and the prevalence of naturally occurring T regulatory cells
    • + cells through the boost of the Th2 phenotype, the inhibition of Th17 response and the prevalence of naturally occurring T regulatory cells. Mol Immunol 2008; 45:4008-19.
    • (2008) Mol Immunol , vol.45 , pp. 4008-4019
    • Martin-Saavedra, F.M.1    Gonzalez-Garcia, C.2    Bravo, B.3    Ballester, S.4
  • 70
    • 36249017932 scopus 로고    scopus 로고
    • IFN-α regulates Toll-like receptor-mediated IL-27 gene expression in human macrophages
    • Pirhonen J, Siren J, Julkunen I, Matikainen S. IFN-α regulates Toll-like receptor-mediated IL-27 gene expression in human macrophages. J Leukoc Biol 2007; 82:1185-92.
    • (2007) J Leukoc Biol , vol.82 , pp. 1185-1192
    • Pirhonen, J.1    Siren, J.2    Julkunen, I.3    Matikainen, S.4
  • 71
    • 0008376732 scopus 로고    scopus 로고
    • Interferon β in the treatment of multiple sclerosis: mechanisms of action
    • Yong VW, Chabot S, Stuve O, Williams G. Interferon β in the treatment of multiple sclerosis: mechanisms of action. Neurology 1998; 51:682-9.
    • (1998) Neurology , vol.51 , pp. 682-689
    • Yong, V.W.1    Chabot, S.2    Stuve, O.3    Williams, G.4
  • 72
    • 0034748842 scopus 로고    scopus 로고
    • Interferon-β therapy downregulates the anti-apoptosis protein FLIP in T cells from patients with multiple sclerosis
    • Sharief MK, Semra YK, Seidi OA, Zoukos Y. Interferon-β therapy downregulates the anti-apoptosis protein FLIP in T cells from patients with multiple sclerosis. J Neuroimmunol 2001; 120:199-207.
    • (2001) J Neuroimmunol , vol.120 , pp. 199-207
    • Sharief, M.K.1    Semra, Y.K.2    Seidi, O.A.3    Zoukos, Y.4
  • 73
    • 28044463388 scopus 로고    scopus 로고
    • Upregulation of TRAIL expression on human T lymphocytes by interferon β and glatiramer acetate
    • Arbour N, Rastikerdar E, McCrea E, Lapierre Y, Dorr J, Bar-Or A, Antel JP. Upregulation of TRAIL expression on human T lymphocytes by interferon β and glatiramer acetate. Mult Scler 2005; 11:652-7.
    • (2005) Mult Scler , vol.11 , pp. 652-657
    • Arbour, N.1    Rastikerdar, E.2    McCrea, E.3    Lapierre, Y.4    Dorr, J.5    Bar-Or, A.6    Antel, J.P.7
  • 74
    • 84856805188 scopus 로고    scopus 로고
    • + regulatory T cells through upregulation of GITRL on dendritic cells in the treatment of multiple sclerosis
    • + regulatory T cells through upregulation of GITRL on dendritic cells in the treatment of multiple sclerosis. J Neuroimmunol 2012; 242:39-46.
    • (2012) J Neuroimmunol , vol.242 , pp. 39-46
    • Chen, M.1    Chen, G.2    Deng, S.3    Liu, X.4    Hutton, G.J.5    Hong, J.6
  • 75
    • 0034333256 scopus 로고    scopus 로고
    • VLA-4/CD49d downregulated on primed T lymphocytes during interferon-β therapy in multiple sclerosis
    • Muraro PA, Leist T, Bielekova B, McFarland HF. VLA-4/CD49d downregulated on primed T lymphocytes during interferon-β therapy in multiple sclerosis. J Neuroimmunol 2000; 111:186-94.
    • (2000) J Neuroimmunol , vol.111 , pp. 186-194
    • Muraro, P.A.1    Leist, T.2    Bielekova, B.3    McFarland, H.F.4
  • 76
    • 30444450277 scopus 로고    scopus 로고
    • Matrix metalloproteinase-9 (MMP-9) and tissue inhibitor of matrix metalloproteinase (TIMP-1) in patients with relapsing-remitting multiple sclerosis treated with interferon β
    • Boz C, Ozmenoglu M, Velioglu S, Kilinc K, Orem A, Alioglu Z, Altunayoglu V. Matrix metalloproteinase-9 (MMP-9) and tissue inhibitor of matrix metalloproteinase (TIMP-1) in patients with relapsing-remitting multiple sclerosis treated with interferon β. Clin Neurol Neurosurg 2006; 108:124-8.
    • (2006) Clin Neurol Neurosurg , vol.108 , pp. 124-128
    • Boz, C.1    Ozmenoglu, M.2    Velioglu, S.3    Kilinc, K.4    Orem, A.5    Alioglu, Z.6    Altunayoglu, V.7
  • 77
    • 58049099896 scopus 로고    scopus 로고
    • Changes in matrix metalloproteinases and their inhibitors during interferon-β treatment in multiple sclerosis
    • Comabella M, Rio J, Espejo C et al. Changes in matrix metalloproteinases and their inhibitors during interferon-β treatment in multiple sclerosis. Clin Immunol 2009; 130:145-50.
    • (2009) Clin Immunol , vol.130 , pp. 145-150
    • Comabella, M.1    Rio, J.2    Espejo, C.3
  • 78
    • 77954478334 scopus 로고    scopus 로고
    • Cutting edge: critical role for PYCARD/ASC in the development of experimental autoimmune encephalomyelitis
    • Shaw PJ, Lukens JR, Burns S, Chi H, McGargill MA, Kanneganti TD. Cutting edge: critical role for PYCARD/ASC in the development of experimental autoimmune encephalomyelitis. J Immunol 2010; 184:4610-4.
    • (2010) J Immunol , vol.184 , pp. 4610-4614
    • Shaw, P.J.1    Lukens, J.R.2    Burns, S.3    Chi, H.4    McGargill, M.A.5    Kanneganti, T.D.6
  • 79
    • 84862649049 scopus 로고    scopus 로고
    • Toll-like receptor (TLR) and inflammasome actions in the central nervous system
    • Hanamsagar R, Hanke ML, Kielian T. Toll-like receptor (TLR) and inflammasome actions in the central nervous system. Trends Immunol 2012; 33:333-42.
    • (2012) Trends Immunol , vol.33 , pp. 333-342
    • Hanamsagar, R.1    Hanke, M.L.2    Kielian, T.3
  • 80
    • 0033017354 scopus 로고    scopus 로고
    • Immunologic therapy of multiple sclerosis
    • Arnason BG. Immunologic therapy of multiple sclerosis. Annu Rev Med 1999; 50:291-302.
    • (1999) Annu Rev Med , vol.50 , pp. 291-302
    • Arnason, B.G.1
  • 81
    • 77950534540 scopus 로고    scopus 로고
    • T helper type 1 and 17 cells determine efficacy of interferon-β in multiple sclerosis and experimental encephalomyelitis
    • Axtell RC, de Jong BA, Boniface K et al. T helper type 1 and 17 cells determine efficacy of interferon-β in multiple sclerosis and experimental encephalomyelitis. Nat Med 2010; 16:406-12.
    • (2010) Nat Med , vol.16 , pp. 406-412
    • Axtell, R.C.1    de, J.B.2    Boniface, K.3
  • 82
    • 0034237667 scopus 로고    scopus 로고
    • Association of two variants in IL-1beta and IL-1 receptor antagonist genes with multiple sclerosis
    • Kantarci OH, Atkinson EJ, Hebrink DD, McMurray CT & Weinshenker BG. Association of two variants in IL-1beta and IL-1 receptor antagonist genes with multiple sclerosis. J Neuroimmunol 2000; 106:220-7.
    • (2000) J Neuroimmunol , vol.106 , pp. 220-227
    • Kantarci, O.H.1    Atkinson, E.J.2    Hebrink, D.D.3    McMurray, C.T.4    Weinshenker, B.G.5
  • 83
    • 0032077870 scopus 로고    scopus 로고
    • Interleukin-1 receptor antagonist suppresses experimental autoimmune encephalomyelitis (EAE) in rats by influencing the activation and proliferation of encephalitogenic cells
    • Badovinac V, Mostarica-Stojkovic M, Dinarello CA & Stosic-Grujicic S. Interleukin-1 receptor antagonist suppresses experimental autoimmune encephalomyelitis (EAE) in rats by influencing the activation and proliferation of encephalitogenic cells. J Neuroimmunol 1998; 85:87-95.
    • (1998) J Neuroimmunol , vol.85 , pp. 87-95
    • Badovinac, V.1    Mostarica-Stojkovic, M.2    Dinarello, C.A.3    Stosic-Grujicic, S.4
  • 84
    • 0034665289 scopus 로고    scopus 로고
    • IL-18 directs autoreactive T cells and promotes autodestruction in the central nervous system via induction of IFN-gamma by NK cells
    • Shi FD, Takeda K, Akira S, Sarvetnick N & Ljunggren HG. IL-18 directs autoreactive T cells and promotes autodestruction in the central nervous system via induction of IFN-gamma by NK cells. J Immunol 2000; 165:3099-3104.
    • (2000) J Immunol , vol.165 , pp. 3099-3104
    • Shi, F.D.1    Takeda, K.2    Akira, S.3    Sarvetnick, N.4    Ljunggren, H.G.5


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