-
1
-
-
77950534540
-
T helper type 1 and 17 cells determine efficacy of interferon-beta in multiple sclerosis and experimental encephalomyelitis
-
Axtell R.C., de Jong B.A., Boniface K., van der Voort L.F., Bhat R., De Sarno P., Naves R., Han M., Zhong F., Castellanos J.G., Mair R., Christakos A., Kolkowitz I., Katz L., Killestein J., Polman C.H., de Waal Malefyt R., Steinman L., Raman C. T helper type 1 and 17 cells determine efficacy of interferon-beta in multiple sclerosis and experimental encephalomyelitis. Nat. Med. 2010, 16:406-412.
-
(2010)
Nat. Med.
, vol.16
, pp. 406-412
-
-
Axtell, R.C.1
de Jong, B.A.2
Boniface, K.3
van der Voort, L.F.4
Bhat, R.5
De Sarno, P.6
Naves, R.7
Han, M.8
Zhong, F.9
Castellanos, J.G.10
Mair, R.11
Christakos, A.12
Kolkowitz, I.13
Katz, L.14
Killestein, J.15
Polman, C.H.16
de Waal Malefyt, R.17
Steinman, L.18
Raman, C.19
-
2
-
-
27444442536
-
Superagonistic anti-CD28 antibodies: potent activators of regulatory T cells for the therapy of autoimmune diseases
-
Beyersdorf N., Hanke T., Kerkau T., Hunig T. Superagonistic anti-CD28 antibodies: potent activators of regulatory T cells for the therapy of autoimmune diseases. Ann. Rheum. Dis. 2005, 64(Suppl. 4):iv91-iv95.
-
(2005)
Ann. Rheum. Dis.
, vol.64
, Issue.SUPPL. 4
-
-
Beyersdorf, N.1
Hanke, T.2
Kerkau, T.3
Hunig, T.4
-
3
-
-
30444450277
-
Matrix metalloproteinase-9 (MMP-9) and tissue inhibitor of matrix metalloproteinase (TIMP-1) in patients with relapsing-remitting multiple sclerosis treated with interferon beta
-
Boz C., Ozmenoglu M., Velioglu S., Kilinc K., Orem A., Alioglu Z., Altunayoglu V. Matrix metalloproteinase-9 (MMP-9) and tissue inhibitor of matrix metalloproteinase (TIMP-1) in patients with relapsing-remitting multiple sclerosis treated with interferon beta. Clin. Neurol. Neurosurg. 2006, 108:124-128.
-
(2006)
Clin. Neurol. Neurosurg.
, vol.108
, pp. 124-128
-
-
Boz, C.1
Ozmenoglu, M.2
Velioglu, S.3
Kilinc, K.4
Orem, A.5
Alioglu, Z.6
Altunayoglu, V.7
-
4
-
-
70349257850
-
+ T Cells in MS
-
+ T Cells in MS. Eur. J. Immunol. 2009, 39:2525-2536.
-
(2009)
Eur. J. Immunol.
, vol.39
, pp. 2525-2536
-
-
Chen, M.1
Chen, G.2
Nie, H.3
Zhang, X.4
Niu, X.5
Zang, Y.C.6
Skinner, S.M.7
Zhang, J.Z.8
Killian, J.M.9
Hong, J.10
-
5
-
-
33845873044
-
+ regulatory T-cell function: an ex vivo and in vitro longitudinal study in relapsing-remitting multiple sclerosis
-
+ regulatory T-cell function: an ex vivo and in vitro longitudinal study in relapsing-remitting multiple sclerosis. J. Neuroimmunol. 2007, 182:204-211.
-
(2007)
J. Neuroimmunol.
, vol.182
, pp. 204-211
-
-
De Andres, C.1
Aristimuno, C.2
de Las Heras, V.3
Martinez-Gines, M.L.4
Bartolome, M.5
Arroyo, R.6
Navarro, J.7
Gimenez-Roldan, S.8
Fernandez-Cruz, E.9
Sanchez-Ramon, S.10
-
6
-
-
43049101640
-
The type I IFN induction pathway constrains Th17-mediated autoimmune inflammation in mice
-
Guo B., Chang E.Y., Cheng G. The type I IFN induction pathway constrains Th17-mediated autoimmune inflammation in mice. J. Clin. Invest. 2008, 118:1680-1690.
-
(2008)
J. Clin. Invest.
, vol.118
, pp. 1680-1690
-
-
Guo, B.1
Chang, E.Y.2
Cheng, G.3
-
7
-
-
27944499757
-
+CD25high regulatory T cells on the T cell immune response against myelin oligodendrocyte glycoprotein in patients with multiple sclerosis
-
+CD25high regulatory T cells on the T cell immune response against myelin oligodendrocyte glycoprotein in patients with multiple sclerosis. Eur. J. Immunol. 2005, 35:3343-3352.
-
(2005)
Eur. J. Immunol.
, vol.35
, pp. 3343-3352
-
-
Haas, J.1
Hug, A.2
Viehover, A.3
Fritzsching, B.4
Falk, C.S.5
Filser, A.6
Vetter, T.7
Milkova, L.8
Korporal, M.9
Fritz, B.10
Storch-Hagenlocher, B.11
Krammer, P.H.12
Suri-Payer, E.13
Wildemann, B.14
-
8
-
-
0347785480
-
Control of regulatory T cell development by the transcription factor Foxp3
-
Hori S., Nomura T., Sakaguchi S. Control of regulatory T cell development by the transcription factor Foxp3. Science 2003, 299:1057-1061.
-
(2003)
Science
, vol.299
, pp. 1057-1061
-
-
Hori, S.1
Nomura, T.2
Sakaguchi, S.3
-
9
-
-
23744515175
-
Decreased FOXP3 levels in multiple sclerosis patients
-
Huan J., Culbertson N., Spencer L., Bartholomew R., Burrows G.G., Chou Y.K., Bourdette D., Ziegler S.F., Offner H., Vandenbark A.A. Decreased FOXP3 levels in multiple sclerosis patients. J. Neurosci. Res. 2005, 81:45-52.
-
(2005)
J. Neurosci. Res.
, vol.81
, pp. 45-52
-
-
Huan, J.1
Culbertson, N.2
Spencer, L.3
Bartholomew, R.4
Burrows, G.G.5
Chou, Y.K.6
Bourdette, D.7
Ziegler, S.F.8
Offner, H.9
Vandenbark, A.A.10
-
10
-
-
77951742201
-
Blockade of GITR-GITRL interaction maintains Treg function to prolong allograft survival
-
Kim J.I., Sonawane S.B., Lee M.K., Lee S.H., Duff P.E., Moore D.J., O'Connor M.R., Lian M.M., Deng S., Choi Y., Yeh H., Caton A.J., Markmann J.F. Blockade of GITR-GITRL interaction maintains Treg function to prolong allograft survival. Eur. J. Immunol. 2010, 40:1369-1374.
-
(2010)
Eur. J. Immunol.
, vol.40
, pp. 1369-1374
-
-
Kim, J.I.1
Sonawane, S.B.2
Lee, M.K.3
Lee, S.H.4
Duff, P.E.5
Moore, D.J.6
O'Connor, M.R.7
Lian, M.M.8
Deng, S.9
Choi, Y.10
Yeh, H.11
Caton, A.J.12
Markmann, J.F.13
-
11
-
-
55949119602
-
Interferon beta-induced restoration of regulatory T-cell function in multiple sclerosis is prompted by an increase in newly generated naive regulatory T cells
-
Korporal M., Haas J., Balint B., Fritzsching B., Schwarz A., Moeller S., Fritz B., Suri-Payer E., Wildemann B. Interferon beta-induced restoration of regulatory T-cell function in multiple sclerosis is prompted by an increase in newly generated naive regulatory T cells. Arch. Neurol. 2008, 65:1434-1439.
-
(2008)
Arch. Neurol.
, vol.65
, pp. 1434-1439
-
-
Korporal, M.1
Haas, J.2
Balint, B.3
Fritzsching, B.4
Schwarz, A.5
Moeller, S.6
Fritz, B.7
Suri-Payer, E.8
Wildemann, B.9
-
12
-
-
0033544319
-
ZInterferon beta induces T-helper 2 immune deviation in MS
-
Kozovska M.E., Hong J., Zang Y.C., Li S., Rivera V.M., Killian J.M., Zhang J.Z. ZInterferon beta induces T-helper 2 immune deviation in MS. Neurology 1999, 53:1692-1697.
-
(1999)
Neurology
, vol.53
, pp. 1692-1697
-
-
Kozovska, M.E.1
Hong, J.2
Zang, Y.C.3
Li, S.4
Rivera, V.M.5
Killian, J.M.6
Zhang, J.Z.7
-
13
-
-
73149090090
-
Effect of IFN-beta therapy on the frequency and function of CD4(+)CD25(+) regulatory T cells and Foxp3 gene expression in relapsing-remitting multiple sclerosis (RRMS): a preliminary study
-
Namdar A., Nikbin B., Ghabaee M., Bayati A., Izad M. Effect of IFN-beta therapy on the frequency and function of CD4(+)CD25(+) regulatory T cells and Foxp3 gene expression in relapsing-remitting multiple sclerosis (RRMS): a preliminary study. J. Neuroimmunol. 2010, 218:120-124.
-
(2010)
J. Neuroimmunol.
, vol.218
, pp. 120-124
-
-
Namdar, A.1
Nikbin, B.2
Ghabaee, M.3
Bayati, A.4
Izad, M.5
-
14
-
-
17444414236
-
GITR: a multifaceted regulator of immunity belonging to the tumor necrosis factor receptor superfamily
-
Nocentini G., Riccardi C. GITR: a multifaceted regulator of immunity belonging to the tumor necrosis factor receptor superfamily. Eur. J. Immunol. 2005, 35:1016-1022.
-
(2005)
Eur. J. Immunol.
, vol.35
, pp. 1016-1022
-
-
Nocentini, G.1
Riccardi, C.2
-
15
-
-
34250341733
-
GITR/GITRL: more than an effector T cell co-stimulatory system
-
Nocentini G., Ronchetti S., Cuzzocrea S., Riccardi C. GITR/GITRL: more than an effector T cell co-stimulatory system. Eur. J. Immunol. 2007, 37:1165-1169.
-
(2007)
Eur. J. Immunol.
, vol.37
, pp. 1165-1169
-
-
Nocentini, G.1
Ronchetti, S.2
Cuzzocrea, S.3
Riccardi, C.4
-
16
-
-
43049177588
-
Distinct and nonredundant in vivo functions of IFNAR on myeloid cells limit autoimmunity in the central nervous system
-
Prinz M., Schmidt H., Mildner A., Knobeloch K.P., Hanisch U.K., Raasch J., Merkler D., Detje C., Gutcher I., Mages J., Lang R., Martin R., Gold R., Becher B., Bruck W., Kalinke U. Distinct and nonredundant in vivo functions of IFNAR on myeloid cells limit autoimmunity in the central nervous system. Immunity 2008, 28:675-686.
-
(2008)
Immunity
, vol.28
, pp. 675-686
-
-
Prinz, M.1
Schmidt, H.2
Mildner, A.3
Knobeloch, K.P.4
Hanisch, U.K.5
Raasch, J.6
Merkler, D.7
Detje, C.8
Gutcher, I.9
Mages, J.10
Lang, R.11
Martin, R.12
Gold, R.13
Becher, B.14
Bruck, W.15
Kalinke, U.16
-
17
-
-
0034679567
-
Cytotoxic T lymphocyte-associated antigen 4 plays an essential role in the function of CD25(+)CD4(+) regulatory cells that control intestinal inflammation
-
Read S., Malmstrom V., Powrie F. Cytotoxic T lymphocyte-associated antigen 4 plays an essential role in the function of CD25(+)CD4(+) regulatory cells that control intestinal inflammation. J. Exp. Med. 2000, 192:295-302.
-
(2000)
J. Exp. Med.
, vol.192
, pp. 295-302
-
-
Read, S.1
Malmstrom, V.2
Powrie, F.3
-
18
-
-
1642379813
-
GITR, a member of the TNF receptor superfamily, is costimulatory to mouse T lymphocyte subpopulations
-
Ronchetti S., Zollo O., Bruscoli S., Agostini M., Bianchini R., Nocentini G., Ayroldi E., Riccardi C. GITR, a member of the TNF receptor superfamily, is costimulatory to mouse T lymphocyte subpopulations. Eur. J. Immunol. 2004, 34:613-622.
-
(2004)
Eur. J. Immunol.
, vol.34
, pp. 613-622
-
-
Ronchetti, S.1
Zollo, O.2
Bruscoli, S.3
Agostini, M.4
Bianchini, R.5
Nocentini, G.6
Ayroldi, E.7
Riccardi, C.8
-
19
-
-
33746575650
-
The GITR-GITRL interaction: co-stimulation or contrasuppression of regulatory activity? Nature reviews
-
Shevach E.M., Stephens G.L. The GITR-GITRL interaction: co-stimulation or contrasuppression of regulatory activity? Nature reviews. Immunology 2006, 6:613-618.
-
(2006)
Immunology
, vol.6
, pp. 613-618
-
-
Shevach, E.M.1
Stephens, G.L.2
-
20
-
-
44449146212
-
Engagement of the type I interferon receptor on dendritic cells inhibits T helper 17 cell development: role of intracellular osteopontin
-
Shinohara M.L., Kim J.H., Garcia V.A., Cantor H. Engagement of the type I interferon receptor on dendritic cells inhibits T helper 17 cell development: role of intracellular osteopontin. Immunity 2008, 29:68-78.
-
(2008)
Immunity
, vol.29
, pp. 68-78
-
-
Shinohara, M.L.1
Kim, J.H.2
Garcia, V.A.3
Cantor, H.4
-
21
-
-
73849110532
-
GITR blockade facilitates Treg mediated allograft survival
-
Sonawane S.B., Kim J.I., Lee M.K., Lee S.H., Duff P.E., Moore D.J., Lian M.M., Deng S., Choi Y., Yeh H., Caton A.J., Markmann J.F. GITR blockade facilitates Treg mediated allograft survival. Transplantation 2009, 88:1169-1177.
-
(2009)
Transplantation
, vol.88
, pp. 1169-1177
-
-
Sonawane, S.B.1
Kim, J.I.2
Lee, M.K.3
Lee, S.H.4
Duff, P.E.5
Moore, D.J.6
Lian, M.M.7
Deng, S.8
Choi, Y.9
Yeh, H.10
Caton, A.J.11
Markmann, J.F.12
-
22
-
-
0031647622
-
+ naturally anergic and suppressive T cells: induction of autoimmune disease by breaking their anergic/suppressive state
-
+ naturally anergic and suppressive T cells: induction of autoimmune disease by breaking their anergic/suppressive state. Int. Immunol. 1998, 10:1969-1980.
-
(1998)
Int. Immunol.
, vol.10
, pp. 1969-1980
-
-
Takahashi, T.1
Kuniyasu, Y.2
Toda, M.3
Sakaguchi, N.4
Itoh, M.5
Iwata, M.6
Shimizu, J.7
Sakaguchi, S.8
-
23
-
-
2942692039
-
+ T cells, expanded with dendritic cells presenting a single autoantigenic peptide, suppress autoimmune diabetes
-
+ T cells, expanded with dendritic cells presenting a single autoantigenic peptide, suppress autoimmune diabetes. J. Exp. Med. 2004, 199:1467-1477.
-
(2004)
J. Exp. Med.
, vol.199
, pp. 1467-1477
-
-
Tarbell, K.V.1
Yamazaki, S.2
Olson, K.3
Toy, P.4
Steinman, R.M.5
-
24
-
-
33846410255
-
+ regulatory T cells restore normoglycemia in diabetic NOD mice
-
+ regulatory T cells restore normoglycemia in diabetic NOD mice. J. Exp. Med. 2007, 204:191-201.
-
(2007)
J. Exp. Med.
, vol.204
, pp. 191-201
-
-
Tarbell, K.V.1
Petit, L.2
Zuo, X.3
Toy, P.4
Luo, X.5
Mqadmi, A.6
Yang, H.7
Suthanthiran, M.8
Mojsov, S.9
Steinman, R.M.10
-
25
-
-
0031821875
-
+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production
-
+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production. J. Exp. Med. 1998, 188:287-296.
-
(1998)
J. Exp. Med.
, vol.188
, pp. 287-296
-
-
Thornton, A.M.1
Shevach, E.M.2
-
26
-
-
0033985780
-
+ immunoregulatory T cells is antigen nonspecific
-
+ immunoregulatory T cells is antigen nonspecific. J. Immunol. 2000, 164:183-190.
-
(2000)
J. Immunol.
, vol.164
, pp. 183-190
-
-
Thornton, A.M.1
Shevach, E.M.2
-
27
-
-
33744904725
-
+ regulatory T-cell function and FOXP3 expression
-
+ regulatory T-cell function and FOXP3 expression. J. Neurosci. Res. 2006, 83:1432-1446.
-
(2006)
J. Neurosci. Res.
, vol.83
, pp. 1432-1446
-
-
Venken, K.1
Hellings, N.2
Hensen, K.3
Rummens, J.L.4
Medaer, R.5
D'Hooghe, M.B.6
Dubois, B.7
Raus, J.8
Stinissen, P.9
-
29
-
-
0042512461
-
+ regulatory T cells by antigen-processing dendritic cells
-
+ regulatory T cells by antigen-processing dendritic cells. J. Exp. Med. 2003, 198:235-247.
-
(2003)
J. Exp. Med.
, vol.198
, pp. 235-247
-
-
Yamazaki, S.1
Iyoda, T.2
Tarbell, K.3
Olson, K.4
Velinzon, K.5
Inaba, K.6
Steinman, R.M.7
-
30
-
-
0142074749
-
Interferon-beta-1 b decreased matrix metalloproteinase-9 serum levels in primary progressive multiple sclerosis
-
Yushchenko M., Mader M., Elitok E., Bitsch A., Dressel A., Tumani H., Bogumil T., Kitze B., Poser S., Weber F. Interferon-beta-1 b decreased matrix metalloproteinase-9 serum levels in primary progressive multiple sclerosis. J. Neurol. 2003, 250:1224-1228.
-
(2003)
J. Neurol.
, vol.250
, pp. 1224-1228
-
-
Yushchenko, M.1
Mader, M.2
Elitok, E.3
Bitsch, A.4
Dressel, A.5
Tumani, H.6
Bogumil, T.7
Kitze, B.8
Poser, S.9
Weber, F.10
|