Dysregulated RasGRP1 responds to cytokine receptor input in T cell leukemogenesis

Science Signaling

Volumn 6, Issue 268, 2013, Pages

  Hartzell, Catherine ^a   Ksionda, Olga ^a   Lemmens, Ed ^a   Coakley, Kristen ^a   Yang, Ming ^b   Dail, Monique ^c   Harvey, Richard C ^d   Govern, Christopher ^b   Bakker, Jeroen ^a   Lenstra, Tineke L ^a   Ammon, Kristin ^c   Boeter, Anne ^a   Winter, Stuart S ^d   Loh, Mignon ^c   Shannon, Kevin ^c   Chakraborty, Arup K ^b,e   Wabl, Matthias ^c   Roose, Jeroen P ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b Massachusetts Institute of Technology Cambridge   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF NEW MEXICO SCHOOL OF MEDICINE   (United States)

^e MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE RECEPTOR; DIACYLGLYCEROL; GUANINE NUCLEOTIDE EXCHANGE FACTOR; INTERLEUKIN 2; INTERLEUKIN 7; INTERLEUKIN 9; RAS PROTEIN; RASGRP1 PROTEIN; UNCLASSIFIED DRUG; OLIGONUCLEOTIDE; PRIMER DNA; RASGRP1 PROTEIN, MOUSE; SMALL INTERFERING RNA;

ACUTE LYMPHOBLASTIC LEUKEMIA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CATALYSIS; CELL CYCLE ARREST; CELL PROLIFERATION; CELL SURVIVAL; CHROMOSOME 10; CONTROLLED STUDY; GENE EXPRESSION PROFILING; GENE INSERTION; HUMAN; HUMAN CELL; IN VIVO STUDY; LEUKEMIA VIRUS; LEUKEMOGENESIS; MOUSE; NONHUMAN; ONCOGENE N RAS; POINT MUTATION; PRE T LYMPHOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; SOMATIC MUTATION; T CELL LEUKEMIA; ANIMAL; BIOLOGICAL MODEL; CELL CYCLE CHECKPOINT; CHILD; ENZYME ACTIVATION; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PHYSIOLOGY; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION;

MUS;

ANIMALS; CELL CYCLE CHECKPOINTS; CELL PROLIFERATION; CHILD; DIGLYCERIDES; DNA PRIMERS; ENZYME ACTIVATION; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; GUANINE NUCLEOTIDE EXCHANGE FACTORS; HUMANS; MICE; MODELS, BIOLOGICAL; MUTAGENESIS, INSERTIONAL; OLIGONUCLEOTIDES; PRECURSOR T-CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; RAS PROTEINS; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION;

EID: 84875736558     PISSN: 19450877     EISSN: 19379145     Source Type: Journal    
DOI: 10.1126/scisignal.2003848     Document Type: Article

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