-
1
-
-
0032502319
-
Selective defect in nitric oxide synthesis may explain the impaired endothelium-dependent vasodilation in patients with essential hypertension
-
Cardillo, C.; Kilcoyne, C.M.; Quyyumi, A.A.; Cannon, R.O., III; Panza, J.A. Selective defect in nitric oxide synthesis may explain the impaired endothelium-dependent vasodilation in patients with essential hypertension. Circulation 1998, 97, 851-856.
-
(1998)
Circulation
, vol.97
, pp. 851-856
-
-
Cardillo, C.1
Kilcoyne, C.M.2
Quyyumi, A.A.3
Cannon III, R.O.4
Panza, J.A.5
-
2
-
-
0032953004
-
Increased NAD(P)H oxidase-mediated superoxide production in renovascular hypertension: Evidence for an involvement of protein kinase C
-
Heitzer, T.; Wenzel, U.; Hink, U.; Krollner, D.; Skatchkov, M.; Stahl, R.A.; MacHarzina, R.; Brasen, J.H.; Meinertz, T.; Munzel, T. Increased NAD(P)H oxidase-mediated superoxide production in renovascular hypertension: evidence for an involvement of protein kinase C. Kidney Int. 1999, 55, 252-260.
-
(1999)
Kidney Int.
, vol.55
, pp. 252-260
-
-
Heitzer, T.1
Wenzel, U.2
Hink, U.3
Krollner, D.4
Skatchkov, M.5
Stahl, R.A.6
McHarzina, R.7
Brasen, J.H.8
Meinertz, T.9
Munzel, T.10
-
3
-
-
0041915623
-
High pressure induces superoxide production in isolated arteries via protein kinase C-dependent activation of NAD(P)H oxidase
-
Ungvari, Z.; Csiszar, A.; Huang, A.; Kaminski, P.M.; Wolin, M.S.; Koller, A. High pressure induces superoxide production in isolated arteries via protein kinase C-dependent activation of NAD(P)H oxidase. Circulation 2003, 108, 1253-1258.
-
(2003)
Circulation
, vol.108
, pp. 1253-1258
-
-
Ungvari, Z.1
Csiszar, A.2
Huang, A.3
Kaminski, P.M.4
Wolin, M.S.5
Koller, A.6
-
4
-
-
33644872836
-
Inflammation and cardiovascular disease mechanisms
-
Libby, P. Inflammation and cardiovascular disease mechanisms. Am. J. Clin. Nutr. 2006, 83, 456S-460S.
-
(2006)
Am. J. Clin. Nutr.
, vol.83
-
-
Libby, P.1
-
5
-
-
13844297894
-
Circulating levels of proinflammatory cytokines and neutrophil-platelet aggregates in patients with coronary artery disease
-
Nijm, J.; Wikby, A.; Tompa, A.; Olsson, A.G.; Jonasson, L. Circulating levels of proinflammatory cytokines and neutrophil-platelet aggregates in patients with coronary artery disease. Am. J. Cardiol. 2005, 95, 452-456.
-
(2005)
Am. J. Cardiol.
, vol.95
, pp. 452-456
-
-
Nijm, J.1
Wikby, A.2
Tompa, A.3
Olsson, A.G.4
Jonasson, L.5
-
6
-
-
24944567085
-
Homocysteine is positively associated with cytokine IL-18 plasma levels in coronary artery bypass surgery patients
-
McLachlan, C.S.; Chua, W.C.; Wong, P.T.; Kah, T.L.; Chen, C.; El Oakley, R.M. Homocysteine is positively associated with cytokine IL-18 plasma levels in coronary artery bypass surgery patients. Biofactors 2005, 23, 69-73.
-
(2005)
Biofactors
, vol.23
, pp. 69-73
-
-
McLachlan, C.S.1
Chua, W.C.2
Wong, P.T.3
Kah, T.L.4
Chen, C.5
El Oakley, R.M.6
-
7
-
-
0032508355
-
Abnormalities of the extracellular degradation of collagen type I in essential hypertension
-
Laviades, C.; Varo, N.; Fernandez, J.; Mayor, G.; Gil, M.J.; Monreal, I.; Diez, J. Abnormalities of the extracellular degradation of collagen type I in essential hypertension. Circulation 1998, 98, 535-540.
-
(1998)
Circulation
, vol.98
, pp. 535-540
-
-
Laviades, C.1
Varo, N.2
Fernandez, J.3
Mayor, G.4
Gil, M.J.5
Monreal, I.6
Diez, J.7
-
8
-
-
4444325595
-
Downregulation of vascular matrix metalloproteinase inducer and activator proteins in hypertensive patients
-
Ergul, A.; Portik-Dobos, V.; Hutchinson, J.; Franco, J.; Anstadt, M.P. Downregulation of vascular matrix metalloproteinase inducer and activator proteins in hypertensive patients. Am. J. Hypertens. 2004, 17, 775-782.
-
(2004)
Am. J. Hypertens.
, vol.17
, pp. 775-782
-
-
Ergul, A.1
Portik-Dobos, V.2
Hutchinson, J.3
Franco, J.4
Anstadt, M.P.5
-
9
-
-
34250796742
-
Morphological and biochemical characterization of remodeling in aorta and vena cava of DOCA-salt hypertensive rats
-
Watts, S.W.; Rondelli, C.; Thakali, K.; Li, X.; Uhal, B.; Pervaiz, M.H.; Watson, R.E.; Fink, G.D. Morphological and biochemical characterization of remodeling in aorta and vena cava of DOCA-salt hypertensive rats. Am. J. Physiol. Heart Circ. Physiol. 2007, 292, H2438-H2448.
-
(2007)
Am. J. Physiol. Heart Circ. Physiol.
, vol.292
-
-
Watts, S.W.1
Rondelli, C.2
Thakali, K.3
Li, X.4
Uhal, B.5
Pervaiz, M.H.6
Watson, R.E.7
Fink, G.D.8
-
10
-
-
0037178897
-
Activation of protein kinase Czeta is essential for cytokine-induced metalloproteinase-1,-3, and-9 secretion from rabbit smooth muscle cells and inhibits proliferation
-
Hussain, S.; Assender, J.W.; Bond, M.; Wong, L.F.; Murphy, D.; Newby, A.C. Activation of protein kinase Czeta is essential for cytokine-induced metalloproteinase-1,-3, and-9 secretion from rabbit smooth muscle cells and inhibits proliferation. J. Biol. Chem. 2002, 277, 27345-27352.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 27345-27352
-
-
Hussain, S.1
Assender, J.W.2
Bond, M.3
Wong, L.F.4
Murphy, D.5
Newby, A.C.6
-
11
-
-
1842495234
-
Protein kinase C-alpha activation by phorbol ester induces secretion of gelatinase B/MMP-9 through ERK 1/2 pathway in capillary endothelial cells
-
Park, M.J.; Park, I.C.; Lee, H.C.; Woo, S.H.; Lee, J.Y.; Hong, Y.J.; Rhee, C.H.; Lee, Y.S.; Lee, S.H.; Shim, B.S.; et al. Protein kinase C-alpha activation by phorbol ester induces secretion of gelatinase B/MMP-9 through ERK 1/2 pathway in capillary endothelial cells. Int. J. Oncol. 2003, 22, 137-143.
-
(2003)
Int. J. Oncol.
, vol.22
, pp. 137-143
-
-
Park, M.J.1
Park, I.C.2
Lee, H.C.3
Woo, S.H.4
Lee, J.Y.5
Hong, Y.J.6
Rhee, C.H.7
Lee, Y.S.8
Lee, S.H.9
Shim, B.S.10
-
12
-
-
33847042684
-
Interleukin-1beta increases expression and activity of matrix metalloproteinase-2 in cardiac microvascular endothelial cells: Role of PKCalpha/beta1 and MAPKs
-
Mountain, D.J.; Singh, M.; Menon, B.; Singh, K. Interleukin-1beta increases expression and activity of matrix metalloproteinase-2 in cardiac microvascular endothelial cells: role of PKCalpha/beta1 and MAPKs. Am. J. Physiol. Cell. Physiol. 2007, 292, C867-C875.
-
(2007)
Am. J. Physiol. Cell. Physiol.
, vol.292
-
-
Mountain, D.J.1
Singh, M.2
Menon, B.3
Singh, K.4
-
13
-
-
8644286380
-
Hypoxic pulmonary vasoconstriction and pulmonary artery tissue cytokine expression are mediated by protein kinase C
-
Tsai, B.M.; Wang, M.; Pitcher, J.M.; Meldrum, K.K.; Meldrum, D.R. Hypoxic pulmonary vasoconstriction and pulmonary artery tissue cytokine expression are mediated by protein kinase C. Am. J. Physiol. Lung Cell. Mol. Physiol. 2004, 287, L1215-L1219.
-
(2004)
Am. J. Physiol. Lung Cell. Mol. Physiol.
, vol.287
-
-
Tsai, B.M.1
Wang, M.2
Pitcher, J.M.3
Meldrum, K.K.4
Meldrum, D.R.5
-
14
-
-
19244385545
-
Aldose reductase mediates the mitogenic signals of cytokines
-
Ramana, K.V.; Chandra, D.; Srivastava, S.; Bhatnagar, A.; Srivastava, S.K. Aldose reductase mediates the mitogenic signals of cytokines. Chem. Biol. Interact. 2003, 143-144, 587-596.
-
(2003)
Chem. Biol. Interact.
, vol.143-144
, pp. 587-596
-
-
Ramana, K.V.1
Chandra, D.2
Srivastava, S.3
Bhatnagar, A.4
Srivastava, S.K.5
-
15
-
-
34548084566
-
Aldose reductase-regulated tumor necrosis factor-alpha production is essential for high glucose-induced vascular smooth muscle cell growth
-
Ramana, K.V.; Tammali, R.; Reddy, A.B.; Bhatnagar, A.; Srivastava, S.K. Aldose reductase-regulated tumor necrosis factor-alpha production is essential for high glucose-induced vascular smooth muscle cell growth. Endocrinology 2007, 148, 4371-4384.
-
(2007)
Endocrinology
, vol.148
, pp. 4371-4384
-
-
Ramana, K.V.1
Tammali, R.2
Reddy, A.B.3
Bhatnagar, A.4
Srivastava, S.K.5
-
16
-
-
0141751697
-
2+ sensitivity of smooth muscle and nonmuscle myosin II: Modulated by G proteins, kinases, and myosin phosphatase
-
2+ sensitivity of smooth muscle and nonmuscle myosin II: Modulated by G proteins, kinases, and myosin phosphatase. Physiol. Rev. 2003, 83, 1325-1358.
-
(2003)
Physiol. Rev.
, vol.83
, pp. 1325-1358
-
-
Somlyo, A.P.1
Somlyo, A.V.2
-
17
-
-
0023850456
-
Sustained contraction of vascular smooth muscle: Calcium influx or C-kinase activation?
-
Khalil, R.A.; van Breemen, C. Sustained contraction of vascular smooth muscle: calcium influx or C-kinase activation? J. Pharmacol. Exp. Ther. 1988, 244, 537-542.
-
(1988)
J. Pharmacol. Exp. Ther.
, vol.244
, pp. 537-542
-
-
Khalil, R.A.1
van Breemen, C.2
-
18
-
-
0029976838
-
Mechanisms of smooth muscle contraction
-
Horowitz, A.; Menice, C.B.; Laporte, R.; Morgan, K.G. Mechanisms of smooth muscle contraction. Physiol. Rev. 1996, 76, 967-1003.
-
(1996)
Physiol. Rev.
, vol.76
, pp. 967-1003
-
-
Horowitz, A.1
Menice, C.B.2
Laporte, R.3
Morgan, K.G.4
-
19
-
-
27544468317
-
Protein kinase C isoforms as specific targets for modulation of vascular smooth muscle function in hypertension
-
Salamanca, D.A.; Khalil, R.A. Protein kinase C isoforms as specific targets for modulation of vascular smooth muscle function in hypertension. Biochem. Pharmacol. 2005, 70, 1537-1547.
-
(2005)
Biochem. Pharmacol.
, vol.70
, pp. 1537-1547
-
-
Salamanca, D.A.1
Khalil, R.A.2
-
20
-
-
0021750054
-
Inositol trisphosphate, a novel second messenger in cellular signal transduction
-
Berridge, M.J.; Irvine, R.F. Inositol trisphosphate, a novel second messenger in cellular signal transduction. Nature 1984, 312, 315-321.
-
(1984)
Nature
, vol.312
, pp. 315-321
-
-
Berridge, M.J.1
Irvine, R.F.2
-
21
-
-
0026451081
-
Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C
-
Nishizuka, Y. Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C. Science 1992, 258, 607-614.
-
(1992)
Science
, vol.258
, pp. 607-614
-
-
Nishizuka, Y.1
-
22
-
-
0026735090
-
Calcium-dependent and calcium-independent pathways of signal transduction in smooth muscle
-
Morgan, K.G.; Khalil, R.A.; Suematsu, E.; Katsuyama, H. Calcium-dependent and calcium-independent pathways of signal transduction in smooth muscle. Jpn. J. Pharmacol. 1992, 58 (Suppl. 2), 47P-53P.
-
(1992)
Jpn. J. Pharmacol.
, vol.58
, Issue.SUPPL. 2
-
-
Morgan, K.G.1
Khalil, R.A.2
Suematsu, E.3
Katsuyama, H.4
-
23
-
-
0024399778
-
Agonist-induced vascular tone
-
Nishimura, J.; Khalil, R.A.; van Breemen, C. Agonist-induced vascular tone. Hypertension 1989, 13, 835-844.
-
(1989)
Hypertension
, vol.13
, pp. 835-844
-
-
Nishimura, J.1
Khalil, R.A.2
van Breemen, C.3
-
24
-
-
0023607764
-
Intracellular calcium levels in phorbol ester-induced contractions of vascular muscle
-
Jiang, M.J.; Morgan, K.G. Intracellular calcium levels in phorbol ester-induced contractions of vascular muscle. Am. J. Physiol. 1987, 253, H1365-H1371.
-
(1987)
Am. J. Physiol.
, vol.253
-
-
Jiang, M.J.1
Morgan, K.G.2
-
25
-
-
0018800888
-
Calcium-dependent activation of a multifunctional protein kinase by membrane phospholipids
-
Takai, Y.; Kishimoto, A.; Iwasa, Y.; Kawahara, Y.; Mori, T.; Nishizuka, Y. Calcium-dependent activation of a multifunctional protein kinase by membrane phospholipids. J. Biol. Chem. 1979, 254, 3692-3695.
-
(1979)
J. Biol. Chem.
, vol.254
, pp. 3692-3695
-
-
Takai, Y.1
Kishimoto, A.2
Iwasa, Y.3
Kawahara, Y.4
Mori, T.5
Nishizuka, Y.6
-
26
-
-
0028811653
-
Protein kinase C: Structure, function, and regulation
-
Newton, A.C. Protein kinase C: structure, function, and regulation. J. Biol. Chem. 1995, 270, 28495-28498.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 28495-28498
-
-
Newton, A.C.1
-
27
-
-
0025373205
-
Solution structure of a zinc finger domain of yeast ADR1
-
Klevit, R.E.; Herriott, J.R.; Horvath, S.J. Solution structure of a zinc finger domain of yeast ADR1. Proteins 1990, 7, 215-226.
-
(1990)
Proteins
, vol.7
, pp. 215-226
-
-
Klevit, R.E.1
Herriott, J.R.2
Horvath, S.J.3
-
28
-
-
0022504365
-
Multiple, distinct forms of bovine and human protein kinase C suggest diversity in cellular signaling pathways
-
Coussens, L.; Parker, P.J.; Rhee, L.; Yang-Feng, T.L.; Chen, E.; Waterfield, M.D.; Francke, U.; Ullrich, A. Multiple, distinct forms of bovine and human protein kinase C suggest diversity in cellular signaling pathways. Science 1986, 233, 859-866.
-
(1986)
Science
, vol.233
, pp. 859-866
-
-
Coussens, L.1
Parker, P.J.2
Rhee, L.3
Yang-Feng, T.L.4
Chen, E.5
Waterfield, M.D.6
Francke, U.7
Ullrich, A.8
-
29
-
-
0028057169
-
Agonist-induced redistribution of calponin in contractile vascular smooth muscle cells
-
Parker, C.A.; Takahashi, K.; Tao, T.; Morgan, K.G. Agonist-induced redistribution of calponin in contractile vascular smooth muscle cells. Am. J. Physiol. 1994, 267, C1262-C1270.
-
(1994)
Am. J. Physiol.
, vol.267
-
-
Parker, C.A.1
Takahashi, K.2
Tao, T.3
Morgan, K.G.4
-
30
-
-
0001613219
-
Protein kinase C zeta subspecies from rat brain: Its structure, expression, and properties
-
Ono, Y.; Fujii, T.; Ogita, K.; Kikkawa, U.; Igarashi, K.; Nishizuka, Y. Protein kinase C zeta subspecies from rat brain: its structure, expression, and properties. Proc. Natl. Acad. Sci. USA 1989, 86, 3099-3103.
-
(1989)
Proc. Natl. Acad. Sci. USA
, vol.86
, pp. 3099-3103
-
-
Ono, Y.1
Fujii, T.2
Ogita, K.3
Kikkawa, U.4
Igarashi, K.5
Nishizuka, Y.6
-
31
-
-
0025259881
-
A point mutation at the putative ATP-binding site of protein kinase C alpha abolishes the kinase activity and renders it down-regulation-insensitive. A molecular link between autophosphorylation and down-regulation
-
Ohno, S.; Konno, Y.; Akita, Y.; Yano, A.; Suzuki, K. A point mutation at the putative ATP-binding site of protein kinase C alpha abolishes the kinase activity and renders it down-regulation-insensitive. A molecular link between autophosphorylation and down-regulation. J. Biol. Chem. 1990, 265, 6296-6300.
-
(1990)
J. Biol. Chem.
, vol.265
, pp. 6296-6300
-
-
Ohno, S.1
Konno, Y.2
Akita, Y.3
Yano, A.4
Suzuki, K.5
-
32
-
-
0024500964
-
Unique substrate specificity and regulatory properties of PKC-epsilon: A rationale for diversity
-
Schaap, D.; Parker, P.J.; Bristol, A.; Kriz, R.; Knopf, J. Unique substrate specificity and regulatory properties of PKC-epsilon: a rationale for diversity. FEBS Lett. 1989, 243, 351-357.
-
(1989)
FEBS Lett.
, vol.243
, pp. 351-357
-
-
Schaap, D.1
Parker, P.J.2
Bristol, A.3
Kriz, R.4
Knopf, J.5
-
33
-
-
0026665459
-
A new member of the protein kinase C family, nPKC theta, predominantly expressed in skeletal muscle
-
Osada, S.; Mizuno, K.; Saido, T.C.; Suzuki, K.; Kuroki, T.; Ohno, S. A new member of the protein kinase C family, nPKC theta, predominantly expressed in skeletal muscle. Mol. Cell. Biol. 1992, 12, 3930-3938.
-
(1992)
Mol. Cell. Biol.
, vol.12
, pp. 3930-3938
-
-
Osada, S.1
Mizuno, K.2
Saido, T.C.3
Suzuki, K.4
Kuroki, T.5
Ohno, S.6
-
34
-
-
0026098402
-
Isolation and characterization of PKC-L, a new member of the protein kinase C-related gene family specifically expressed in lung, skin, and heart
-
Bacher, N.; Zisman, Y.; Berent, E.; Livneh, E. Isolation and characterization of PKC-L, a new member of the protein kinase C-related gene family specifically expressed in lung, skin, and heart. Mol. Cell. Biol. 1991, 11, 126-133.
-
(1991)
Mol. Cell. Biol.
, vol.11
, pp. 126-133
-
-
Bacher, N.1
Zisman, Y.2
Berent, E.3
Livneh, E.4
-
35
-
-
0028260337
-
Platelet-derived growth factor and angiotensin II induce different spatial distribution of protein kinase C-alpha and-beta in vascular smooth muscle cells
-
Haller, H.; Quass, P.; Lindschau, C.; Luft, F.C.; Distler, A. Platelet-derived growth factor and angiotensin II induce different spatial distribution of protein kinase C-alpha and-beta in vascular smooth muscle cells. Hypertension 1994, 23, 848-852.
-
(1994)
Hypertension
, vol.23
, pp. 848-852
-
-
Haller, H.1
Quass, P.2
Lindschau, C.3
Luft, F.C.4
Distler, A.5
-
36
-
-
0025219922
-
Phorbol ester-induced stress and myosin light chain phosphorylation in swine carotid medial smooth muscle
-
Singer, H.A. Phorbol ester-induced stress and myosin light chain phosphorylation in swine carotid medial smooth muscle. J. Pharmacol. Exp. Ther. 1990, 252, 1068-1074.
-
(1990)
J. Pharmacol. Exp. Ther.
, vol.252
, pp. 1068-1074
-
-
Singer, H.A.1
-
37
-
-
0029665098
-
Identification of protein kinase C isoforms in rat mesenteric small arteries and their possible role in agonist-induced contraction
-
Ohanian, V.; Ohanian, J.; Shaw, L.; Scarth, S.; Parker, P.J.; Heagerty, A.M. Identification of protein kinase C isoforms in rat mesenteric small arteries and their possible role in agonist-induced contraction. Circ. Res. 1996, 78, 806-812.
-
(1996)
Circ. Res.
, vol.78
, pp. 806-812
-
-
Ohanian, V.1
Ohanian, J.2
Shaw, L.3
Scarth, S.4
Parker, P.J.5
Heagerty, A.M.6
-
38
-
-
0034003793
-
Preconditioning of coronary artery against vasoconstriction by endothelin-1 and prostaglandin F2alpha during repeated downregulation of epsilon-protein kinase C
-
Kanashiro, C.A.; Altirkawi, K.A.; Khalil, R.A. Preconditioning of coronary artery against vasoconstriction by endothelin-1 and prostaglandin F2alpha during repeated downregulation of epsilon-protein kinase C. J. Cardiovasc. Pharmacol. 2000, 35, 491-501.
-
(2000)
J. Cardiovasc. Pharmacol.
, vol.35
, pp. 491-501
-
-
Kanashiro, C.A.1
Altirkawi, K.A.2
Khalil, R.A.3
-
39
-
-
0024411214
-
Identification of type III protein kinase C in bovine aortic tissue
-
Watanabe, M.; Hachiya, T.; Hagiwara, M.; Hidaka, H. Identification of type III protein kinase C in bovine aortic tissue. Arch. Biochem. Biophys. 1989, 273, 165-169.
-
(1989)
Arch. Biochem. Biophys.
, vol.273
, pp. 165-169
-
-
Watanabe, M.1
Hachiya, T.2
Hagiwara, M.3
Hidaka, H.4
-
40
-
-
0028446551
-
2+]i threshold for translocation of the alpha-protein kinase C isoform
-
2+]i threshold for translocation of the alpha-protein kinase C isoform. Am. J. Physiol. 1994, 266, C1544-C1551.
-
(1994)
Am. J. Physiol.
, vol.266
-
-
Khalil, R.A.1
Lajoie, C.2
Morgan, K.G.3
-
41
-
-
0028008196
-
Redistribution of protein kinase C isoforms in association with vascular hypertrophy of rat aorta
-
Liou, Y.M.; Morgan, K.G. Redistribution of protein kinase C isoforms in association with vascular hypertrophy of rat aorta. Am. J. Physiol. 1994, 267, C980-C989.
-
(1994)
Am. J. Physiol.
, vol.267
-
-
Liou, Y.M.1
Morgan, K.G.2
-
42
-
-
0026649431
-
Ca(2+)-independent isoforms of protein kinase C differentially translocate in smooth muscle
-
Khalil, R.A.; Lajoie, C.; Resnick, M.S.; Morgan, K.G. Ca(2+)-independent isoforms of protein kinase C differentially translocate in smooth muscle. Am. J. Physiol. 1992, 263, C714-C719.
-
(1992)
Am. J. Physiol.
, vol.263
-
-
Khalil, R.A.1
Lajoie, C.2
Resnick, M.S.3
Morgan, K.G.4
-
43
-
-
0028900634
-
Immunocytochemical localization of eight protein kinase C isozymes overexpressed in NIH 3T3 fibroblasts. Isoform-specific association with microfilaments, Golgi, endoplasmic reticulum, and nuclear and cell membranes
-
Goodnight, J.A.; Mischak, H.; Kolch, W.; Mushinski, J.F. Immunocytochemical localization of eight protein kinase C isozymes overexpressed in NIH 3T3 fibroblasts. Isoform-specific association with microfilaments, Golgi, endoplasmic reticulum, and nuclear and cell membranes. J. Biol. Chem. 1995, 270, 9991-10001.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 9991-10001
-
-
Goodnight, J.A.1
Mischak, H.2
Kolch, W.3
Mushinski, J.F.4
-
44
-
-
0030978275
-
Possible role of atypical protein kinase C activated by arachidonic acid in Ca2+ sensitization of rabbit smooth muscle
-
Gailly, P.; Gong, M.C.; Somlyo, A.V.; Somlyo, A.P. Possible role of atypical protein kinase C activated by arachidonic acid in Ca2+ sensitization of rabbit smooth muscle. J. Physiol. 1997, 500, 95-109.
-
(1997)
J. Physiol.
, vol.500
, pp. 95-109
-
-
Gailly, P.1
Gong, M.C.2
Somlyo, A.V.3
Somlyo, A.P.4
-
45
-
-
0024469531
-
Complete activation of protein kinase C by an antipeptide antibody directed against the pseudosubstrate prototope
-
Makowske, M.; Rosen, O.M. Complete activation of protein kinase C by an antipeptide antibody directed against the pseudosubstrate prototope. J. Biol. Chem. 1989, 264, 16155-16159.
-
(1989)
J. Biol. Chem.
, vol.264
, pp. 16155-16159
-
-
Makowske, M.1
Rosen, O.M.2
-
46
-
-
0026741799
-
Reversible exposure of the pseudosubstrate domain of protein kinase C by phosphatidylserine and diacylglycerol
-
Orr, J.W.; Keranen, L.M.; Newton, A.C. Reversible exposure of the pseudosubstrate domain of protein kinase C by phosphatidylserine and diacylglycerol. J. Biol. Chem. 1992, 267, 15263-15266.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 15263-15266
-
-
Orr, J.W.1
Keranen, L.M.2
Newton, A.C.3
-
47
-
-
0023555557
-
Protein kinase C contains a pseudosubstrate prototope in its regulatory domain
-
House, C.; Kemp, B.E. Protein kinase C contains a pseudosubstrate prototope in its regulatory domain. Science 1987, 238, 1726-1728.
-
(1987)
Science
, vol.238
, pp. 1726-1728
-
-
House, C.1
Kemp, B.E.2
-
48
-
-
0027296776
-
Mutagenesis of the regulatory domain of rat protein kinase C-eta. A molecular basis for restricted histone kinase activity
-
Dekker, L.V.; McIntyre, P.; Parker, P.J. Mutagenesis of the regulatory domain of rat protein kinase C-eta. A molecular basis for restricted histone kinase activity. J. Biol. Chem. 1993, 268, 19498-19504.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 19498-19504
-
-
Dekker, L.V.1
McIntyre, P.2
Parker, P.J.3
-
49
-
-
0032421728
-
Signal transduction by protein kinase C in mammalian cells
-
Kanashiro, C.A.; Khalil, R.A. Signal transduction by protein kinase C in mammalian cells. Clin. Exp. Pharmacol. Physiol. 1998, 25, 974-985.
-
(1998)
Clin. Exp. Pharmacol. Physiol.
, vol.25
, pp. 974-985
-
-
Kanashiro, C.A.1
Khalil, R.A.2
-
50
-
-
0003474551
-
Phosphorylation and associated translocation of the 87-kDa protein, a major protein kinase C substrate, in isolated nerve terminals
-
Wang, J.K.; Walaas, S.I.; Sihra, T.S.; Aderem, A.; Greengard, P. Phosphorylation and associated translocation of the 87-kDa protein, a major protein kinase C substrate, in isolated nerve terminals. Proc. Natl. Acad. Sci. USA 1989, 86, 2253-2256.
-
(1989)
Proc. Natl. Acad. Sci. USA
, vol.86
, pp. 2253-2256
-
-
Wang, J.K.1
Walaas, S.I.2
Sihra, T.S.3
Aderem, A.4
Greengard, P.5
-
51
-
-
0026513601
-
MARCKS is an actin filament crosslinking protein regulated by protein kinase C and calcium-calmodulin
-
Hartwig, J.H.; Thelen, M.; Rosen, A.; Janmey, P.A.; Nairn, A.C.; Aderem, A. MARCKS is an actin filament crosslinking protein regulated by protein kinase C and calcium-calmodulin. Nature 1992, 356, 618-622.
-
(1992)
Nature
, vol.356
, pp. 618-622
-
-
Hartwig, J.H.1
Thelen, M.2
Rosen, A.3
Janmey, P.A.4
Nairn, A.C.5
Aderem, A.6
-
52
-
-
0022357080
-
Protein kinase C phosphorylates the inhibitory guanine-nucleotide-binding regulatory component and apparently suppresses its function in hormonal inhibition of adenylate cyclase
-
Katada, T.; Gilman, A.G.; Watanabe, Y.; Bauer, S.; Jakobs, K.H. Protein kinase C phosphorylates the inhibitory guanine-nucleotide-binding regulatory component and apparently suppresses its function in hormonal inhibition of adenylate cyclase. Eur. J. Biochem. 1985, 151, 431-437.
-
(1985)
Eur. J. Biochem.
, vol.151
, pp. 431-437
-
-
Katada, T.1
Gilman, A.G.2
Watanabe, Y.3
Bauer, S.4
Jakobs, K.H.5
-
53
-
-
0347988192
-
Protein kinase C inhibits BKCa channel activity in pulmonary arterial smooth muscle
-
Barman, S.A.; Zhu, S.; White, R.E. Protein kinase C inhibits BKCa channel activity in pulmonary arterial smooth muscle. Am. J. Physiol. Lung Cell. Mol. Physiol. 2004, 286, L149-L155.
-
(2004)
Am. J. Physiol. Lung Cell. Mol. Physiol.
, vol.286
-
-
Barman, S.A.1
Zhu, S.2
White, R.E.3
-
54
-
-
0141752820
-
Thromboxane A2-induced inhibition of voltage-gated K+ channels and pulmonary vasoconstriction: Role of protein kinase Czeta
-
Cogolludo, A.; Moreno, L.; Bosca, L.; Tamargo, J.; Perez-Vizcaino, F. Thromboxane A2-induced inhibition of voltage-gated K+ channels and pulmonary vasoconstriction: role of protein kinase Czeta. Circ. Res. 2003, 93, 656-663.
-
(2003)
Circ. Res.
, vol.93
, pp. 656-663
-
-
Cogolludo, A.1
Moreno, L.2
Bosca, L.3
Tamargo, J.4
Perez-Vizcaino, F.5
-
55
-
-
0019327228
-
Phosphorylation of cardiac sarcoplasmic reticulum by a calcium-activated, phospholipid-dependent protein kinase
-
Limas, C.J. Phosphorylation of cardiac sarcoplasmic reticulum by a calcium-activated, phospholipid-dependent protein kinase. Biochem. Biophys. Res. Commun. 1980, 96, 1378-1383.
-
(1980)
Biochem. Biophys. Res. Commun.
, vol.96
, pp. 1378-1383
-
-
Limas, C.J.1
-
57
-
-
0028182616
-
+ antiport, protein kinase C trio in essential hypertension
-
+ antiport, protein kinase C trio in essential hypertension. Am. J. Hypertens. 1994, 7, 205-212.
-
(1994)
Am. J. Hypertens.
, vol.7
, pp. 205-212
-
-
Aviv, A.1
-
58
-
-
0029879590
-
Intramolecular interactions regulate serine/threonine phosphorylation of vinculin
-
Schwienbacher, C.; Jockusch, B.M.; Rudiger, M. Intramolecular interactions regulate serine/threonine phosphorylation of vinculin. FEBS Lett. 1996, 384, 71-74.
-
(1996)
FEBS Lett.
, vol.384
, pp. 71-74
-
-
Schwienbacher, C.1
Jockusch, B.M.2
Rudiger, M.3
-
59
-
-
0035449930
-
Expression of CPI-17 and myosin phosphatase correlates with Ca(2+) sensitivity of protein kinase C-induced contraction in rabbit smooth muscle
-
Woodsome, T.P.; Eto, M.; Everett, A.; Brautigan, D.L.; Kitazawa, T. Expression of CPI-17 and myosin phosphatase correlates with Ca(2+) sensitivity of protein kinase C-induced contraction in rabbit smooth muscle. J. Physiol. 2001, 535, 553-564.
-
(2001)
J. Physiol.
, vol.535
, pp. 553-564
-
-
Woodsome, T.P.1
Eto, M.2
Everett, A.3
Brautigan, D.L.4
Kitazawa, T.5
-
60
-
-
0023247116
-
Purified rabbit brain protein kinase C relaxes skinned vascular smooth muscle and phosphorylates myosin light chain
-
Inagaki, M.; Yokokura, H.; Itoh, T.; Kanmura, Y.; Kuriyama, H.; Hidaka, H. Purified rabbit brain protein kinase C relaxes skinned vascular smooth muscle and phosphorylates myosin light chain. Arch. Biochem. Biophys. 1987, 254, 136-141.
-
(1987)
Arch. Biochem. Biophys.
, vol.254
, pp. 136-141
-
-
Inagaki, M.1
Yokokura, H.2
Itoh, T.3
Kanmura, Y.4
Kuriyama, H.5
Hidaka, H.6
-
61
-
-
0030987070
-
Regulation of protein kinase C
-
Newton, A.C. Regulation of protein kinase C. Curr. Opin. Cell. Biol. 1997, 9, 161-167.
-
(1997)
Curr. Opin. Cell. Biol.
, vol.9
, pp. 161-167
-
-
Newton, A.C.1
-
62
-
-
0031964645
-
Anchoring proteins for protein kinase C: A means for isozyme selectivity
-
Mochly-Rosen, D.; Gordon, A.S. Anchoring proteins for protein kinase C: A means for isozyme selectivity. FASEB J. 1998, 12, 35-42.
-
(1998)
FASEB J.
, vol.12
, pp. 35-42
-
-
Mochly-Rosen, D.1
Gordon, A.S.2
-
63
-
-
0020698115
-
2+, phospholipid-dependent protein kinase associated with plasma membrane
-
2+, phospholipid-dependent protein kinase associated with plasma membrane. Nature 1983, 301, 621-623.
-
(1983)
Nature
, vol.301
, pp. 621-623
-
-
Kraft, A.S.1
Anderson, W.B.2
-
64
-
-
0025330085
-
Protein kinase C is localized in focal contacts of normal but not transformed fibroblasts
-
Hyatt, S.L.; Klauck, T.; Jaken, S. Protein kinase C is localized in focal contacts of normal but not transformed fibroblasts. Mol. Carcinog. 1990, 3, 45-53.
-
(1990)
Mol. Carcinog.
, vol.3
, pp. 45-53
-
-
Hyatt, S.L.1
Klauck, T.2
Jaken, S.3
-
65
-
-
0024273138
-
Electron microscopic localization of type I protein kinase C in rat Purkinje cells
-
Kose, A.; Saito, N.; Ito, H.; Kikkawa, U.; Nishizuka, Y.; Tanaka, C. Electron microscopic localization of type I protein kinase C in rat Purkinje cells. J. Neurosci. 1988, 8, 4262-4268.
-
(1988)
J. Neurosci.
, vol.8
, pp. 4262-4268
-
-
Kose, A.1
Saito, N.2
Ito, H.3
Kikkawa, U.4
Nishizuka, Y.5
Tanaka, C.6
-
67
-
-
17644420707
-
Domain architecture of the smooth-muscle plasma membrane: Regulation by annexins
-
Draeger, A.; Wray, S.; Babiychuk, E.B. Domain architecture of the smooth-muscle plasma membrane: regulation by annexins. Biochem. J. 2005, 387, 309-314.
-
(2005)
Biochem. J.
, vol.387
, pp. 309-314
-
-
Draeger, A.1
Wray, S.2
Babiychuk, E.B.3
-
68
-
-
0025907984
-
Regulation by phosphorylation of reversible association of a myristoylated protein kinase C substrate with the plasma membrane
-
Thelen, M.; Rosen, A.; Nairn, A.C.; Aderem, A. Regulation by phosphorylation of reversible association of a myristoylated protein kinase C substrate with the plasma membrane. Nature 1991, 351, 320-322.
-
(1991)
Nature
, vol.351
, pp. 320-322
-
-
Thelen, M.1
Rosen, A.2
Nairn, A.C.3
Aderem, A.4
-
69
-
-
0027171485
-
Identification of the phosphorylated region responsible for the permissive activation of protein kinase C
-
Cazaubon, S.M.; Parker, P.J. Identification of the phosphorylated region responsible for the permissive activation of protein kinase C. J. Biol. Chem. 1993, 268, 17559-17563.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 17559-17563
-
-
Cazaubon, S.M.1
Parker, P.J.2
-
70
-
-
0027251772
-
Activation of protein kinase C by selective binding of arginine-rich polypeptides
-
Leventhal, P.S.; Bertics, P.J. Activation of protein kinase C by selective binding of arginine-rich polypeptides. J. Biol. Chem. 1993, 268, 13906-13913.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 13906-13913
-
-
Leventhal, P.S.1
Bertics, P.J.2
-
71
-
-
0028059490
-
Agonists and antagonists of protein kinase C function, derived from its binding proteins
-
Ron, D.; Mochly-Rosen, D. Agonists and antagonists of protein kinase C function, derived from its binding proteins. J. Biol. Chem. 1994, 269, 21395-21398.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 21395-21398
-
-
Ron, D.1
Mochly-Rosen, D.2
-
72
-
-
0024284828
-
Overproduction of protein kinase C causes disordered growth control in rat fibroblasts
-
Housey, G.M.; Johnson, M.D.; Hsiao, W.L.; O'Brian, C.A.; Murphy, J.P.; Kirschmeier, P.; Weinstein, I.B. Overproduction of protein kinase C causes disordered growth control in rat fibroblasts. Cell 1988, 52, 343-354.
-
(1988)
Cell
, vol.52
, pp. 343-354
-
-
Housey, G.M.1
Johnson, M.D.2
Hsiao, W.L.3
O'Brian, C.A.4
Murphy, J.P.5
Kirschmeier, P.6
Weinstein, I.B.7
-
73
-
-
0242678496
-
2+ antagonist-insensitive coronary smooth muscle contraction involves activation of epsilon-protein kinase C-dependent pathway
-
2+ antagonist-insensitive coronary smooth muscle contraction involves activation of epsilon-protein kinase C-dependent pathway. Am. J. Physiol. Cell. Physiol. 2003, 285, C1454-C1463.
-
(2003)
Am. J. Physiol. Cell. Physiol.
, vol.285
-
-
Dallas, A.1
Khalil, R.A.2
-
74
-
-
0029021180
-
Phosphotyrosine-dependent targeting of mitogen-activated protein kinase in differentiated contractile vascular cells
-
Khalil, R.A.; Menice, C.B.; Wang, C.L.; Morgan, K.G. Phosphotyrosine-dependent targeting of mitogen-activated protein kinase in differentiated contractile vascular cells. Circ. Res. 1995, 76, 1101-1108.
-
(1995)
Circ. Res.
, vol.76
, pp. 1101-1108
-
-
Khalil, R.A.1
Menice, C.B.2
Wang, C.L.3
Morgan, K.G.4
-
75
-
-
0344149979
-
Mitogen-activated protein kinase and proliferation of human vascular smooth muscle cells
-
Mii, S.; Khalil, R.A.; Morgan, K.G.; Ware, J.A.; Kent, K.C. Mitogen-activated protein kinase and proliferation of human vascular smooth muscle cells. Am. J. Physiol. 1996, 270, H142-H150.
-
(1996)
Am. J. Physiol.
, vol.270
-
-
Mii, S.1
Khalil, R.A.2
Morgan, K.G.3
Ware, J.A.4
Kent, K.C.5
-
76
-
-
0026519840
-
Phosphorylation sequences in h-caldesmon from phorbol ester-stimulated canine aortas
-
Adam, L.P.; Gapinski, C.J.; Hathaway, D.R. Phosphorylation sequences in h-caldesmon from phorbol ester-stimulated canine aortas. FEBS Lett. 1992, 302, 223-226.
-
(1992)
FEBS Lett.
, vol.302
, pp. 223-226
-
-
Adam, L.P.1
Gapinski, C.J.2
Hathaway, D.R.3
-
77
-
-
0033570095
-
Mammal-specific, ERK-dependent, caldesmon phosphorylation in smooth muscle. Quantitation using novel anti-phosphopeptide antibodies
-
D'Angelo, G.; Graceffa, P.; Wang, C.A.; Wrangle, J.; Adam, L.P. Mammal-specific, ERK-dependent, caldesmon phosphorylation in smooth muscle. Quantitation using novel anti-phosphopeptide antibodies. J. Biol. Chem. 1999, 274, 30115-30121.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 30115-30121
-
-
D'Angelo, G.1
Graceffa, P.2
Wang, C.A.3
Wrangle, J.4
Adam, L.P.5
-
78
-
-
0034129032
-
Phosphorylation of caldesmon by ERK MAP kinases in smooth muscle
-
Hedges, J.C.; Oxhorn, B.C.; Carty, M.; Adam, L.P.; Yamboliev, I.A.; Gerthoffer, W.T. Phosphorylation of caldesmon by ERK MAP kinases in smooth muscle. Am. J. Physiol. Cell. Physiol. 2000, 278, C718-C726.
-
(2000)
Am. J. Physiol. Cell. Physiol.
, vol.278
-
-
Hedges, J.C.1
Oxhorn, B.C.2
Carty, M.3
Adam, L.P.4
Yamboliev, I.A.5
Gerthoffer, W.T.6
-
79
-
-
0025170867
-
Protein kinase C interaction with calcium: A phospholipid-dependent process
-
Bazzi, M.D.; Nelsestuen, G.L. Protein kinase C interaction with calcium: A phospholipid-dependent process. Biochemistry 1990, 29, 7624-7630.
-
(1990)
Biochemistry
, vol.29
, pp. 7624-7630
-
-
Bazzi, M.D.1
Nelsestuen, G.L.2
-
80
-
-
0029060391
-
Protein kinase C and lipid signaling for sustained cellular responses
-
Nishizuka, Y. Protein kinase C and lipid signaling for sustained cellular responses. FASEB J. 1995, 9, 484-496.
-
(1995)
FASEB J.
, vol.9
, pp. 484-496
-
-
Nishizuka, Y.1
-
81
-
-
0028055160
-
Differential regulation of protein kinase C isozymes by bryostatin 1 and phorbol 12-myristate 13-acetate in NIH 3T3 fibroblasts
-
Szallasi, Z.; Smith, C.B.; Pettit, G.R.; Blumberg, P.M. Differential regulation of protein kinase C isozymes by bryostatin 1 and phorbol 12-myristate 13-acetate in NIH 3T3 fibroblasts. J. Biol. Chem. 1994, 269, 2118-2124.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 2118-2124
-
-
Szallasi, Z.1
Smith, C.B.2
Pettit, G.R.3
Blumberg, P.M.4
-
82
-
-
0035093166
-
Oxidized-LDL enhances coronary vasoconstriction by increasing the activity of protein kinase C isoforms alpha and epsilon
-
Giardina, J.B.; Tanner, D.J.; Khalil, R.A. Oxidized-LDL enhances coronary vasoconstriction by increasing the activity of protein kinase C isoforms alpha and epsilon. Hypertension 2001, 37, 561-568.
-
(2001)
Hypertension
, vol.37
, pp. 561-568
-
-
Giardina, J.B.1
Tanner, D.J.2
Khalil, R.A.3
-
83
-
-
34548063737
-
alpha-and epsilon-protein kinase C activity during smooth muscle cell apoptosis in response to gamma-radiation
-
Claro, S.; Kanashiro, C.A.; Oshiro, M.E.; Ferreira, A.T.; Khalil, R.A. alpha-and epsilon-protein kinase C activity during smooth muscle cell apoptosis in response to gamma-radiation. J. Pharmacol. Exp. Ther. 2007, 322, 964-972.
-
(2007)
J. Pharmacol. Exp. Ther.
, vol.322
, pp. 964-972
-
-
Claro, S.1
Kanashiro, C.A.2
Oshiro, M.E.3
Ferreira, A.T.4
Khalil, R.A.5
-
84
-
-
0030870169
-
Identification of serine 643 of protein kinase C-delta as an important autophosphorylation site for its enzymatic activity
-
Li, W.; Zhang, J.; Bottaro, D.P.; Pierce, J.H. Identification of serine 643 of protein kinase C-delta as an important autophosphorylation site for its enzymatic activity. J. Biol. Chem. 1997, 272, 24550-24555.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 24550-24555
-
-
Li, W.1
Zhang, J.2
Bottaro, D.P.3
Pierce, J.H.4
-
85
-
-
0029615509
-
Protein kinase C is regulated in vivo by three functionally distinct phosphorylations
-
Keranen, L.M.; Dutil, E.M.; Newton, A.C. Protein kinase C is regulated in vivo by three functionally distinct phosphorylations. Curr. Biol. 1995, 5, 1394-1403.
-
(1995)
Curr. Biol.
, vol.5
, pp. 1394-1403
-
-
Keranen, L.M.1
Dutil, E.M.2
Newton, A.C.3
-
86
-
-
0030875555
-
Phosphorylation at conserved carboxyl-terminal hydrophobic motif regulates the catalytic and regulatory domains of protein kinase C
-
Edwards, A.S.; Newton, A.C. Phosphorylation at conserved carboxyl-terminal hydrophobic motif regulates the catalytic and regulatory domains of protein kinase C. J. Biol. Chem. 1997, 272, 18382-18390.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 18382-18390
-
-
Edwards, A.S.1
Newton, A.C.2
-
87
-
-
0027505810
-
A myristoylated pseudosubstrate peptide, a novel protein kinase C inhibitor
-
Eichholtz, T.; de Bont, D.B.; de Widt, J.; Liskamp, R.M.; Ploegh, H.L. A myristoylated pseudosubstrate peptide, a novel protein kinase C inhibitor. J. Biol. Chem. 1993, 268, 1982-1986.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 1982-1986
-
-
Eichholtz, T.1
de Bont, D.B.2
de Widt, J.3
Liskamp, R.M.4
Ploegh, H.L.5
-
88
-
-
0030905345
-
The effect of alpha-tocopherol on the synthesis, phosphorylation and activity of protein kinase C in smooth muscle cells after phorbol 12-myristate 13-acetate down-regulation
-
Clement, S.; Tasinato, A.; Boscoboinik, D.; Azzi, A. The effect of alpha-tocopherol on the synthesis, phosphorylation and activity of protein kinase C in smooth muscle cells after phorbol 12-myristate 13-acetate down-regulation. Eur. J. Biochem. 1997, 246, 745-749.
-
(1997)
Eur. J. Biochem.
, vol.246
, pp. 745-749
-
-
Clement, S.1
Tasinato, A.2
Boscoboinik, D.3
Azzi, A.4
-
89
-
-
0036141855
-
Pathophysiology of essential hypertension: Role of the pump, the vessel, and the kidney
-
Cain, A.E.; Khalil, R.A. Pathophysiology of essential hypertension: role of the pump, the vessel, and the kidney. Semin. Nephrol. 2002, 22, 3-16.
-
(2002)
Semin. Nephrol.
, vol.22
, pp. 3-16
-
-
Cain, A.E.1
Khalil, R.A.2
-
90
-
-
0031563802
-
Effects of protein kinase C alpha overexpression on A7r5 smooth muscle cell proliferation and differentiation
-
Wang, S.; Desai, D.; Wright, G.; Niles, R.M.; Wright, G.L. Effects of protein kinase C alpha overexpression on A7r5 smooth muscle cell proliferation and differentiation. Exp. Cell. Res. 1997, 236, 117-126.
-
(1997)
Exp. Cell. Res.
, vol.236
, pp. 117-126
-
-
Wang, S.1
Desai, D.2
Wright, G.3
Niles, R.M.4
Wright, G.L.5
-
91
-
-
0033838125
-
Familial primary pulmonary hypertension (gene PPH1) is caused by mutations in the bone morphogenetic protein receptor-II gene
-
Deng, Z.; Morse, J.H.; Slager, S.L.; Cuervo, N.; Moore, K.J.; Venetos, G.; Kalachikov, S.; Cayanis, E.; Fischer, S.G.; Barst, R.J.; Hodge, S.E.; Knowles, J.A. Familial primary pulmonary hypertension (gene PPH1) is caused by mutations in the bone morphogenetic protein receptor-II gene. Am. J. Hum. Genet. 2000, 67, 737-744.
-
(2000)
Am. J. Hum. Genet.
, vol.67
, pp. 737-744
-
-
Deng, Z.1
Morse, J.H.2
Slager, S.L.3
Cuervo, N.4
Moore, K.J.5
Venetos, G.6
Kalachikov, S.7
Cayanis, E.8
Fischer, S.G.9
Barst, R.J.10
Hodge, S.E.11
Knowles, J.A.12
-
92
-
-
0035163071
-
BMPR2 haploinsufficiency as the inherited molecular mechanism for primary pulmonary hypertension
-
Machado, R.D.; Pauciulo, M.W.; Thomson, J.R.; Lane, K.B.; Morgan, N.V.; Wheeler, L.; Phillips, J.A., III; Newman, J.; Williams, D.; Galie, N.; et al. BMPR2 haploinsufficiency as the inherited molecular mechanism for primary pulmonary hypertension. Am. J. Hum. Genet. 2001, 68, 92-102.
-
(2001)
Am. J. Hum. Genet.
, vol.68
, pp. 92-102
-
-
McHado, R.D.1
Pauciulo, M.W.2
Thomson, J.R.3
Lane, K.B.4
Morgan, N.V.5
Wheeler, L.6
Phillips III, J.A.7
Newman, J.8
Williams, D.9
Galie, N.10
-
93
-
-
32544438253
-
BMPR2 gene rearrangements account for a significant proportion of mutations in familial and idiopathic pulmonary arterial hypertension
-
Aldred, M.A.; Vijayakrishnan, J.; James, V.; Soubrier, F.; Gomez-Sanchez, M.A.; Martensson, G.; Galie, N.; Manes, A.; Corris, P.; Simonneau, G.; et al. BMPR2 gene rearrangements account for a significant proportion of mutations in familial and idiopathic pulmonary arterial hypertension. Hum. Mutat. 2006, 27, 212-213.
-
(2006)
Hum. Mutat.
, vol.27
, pp. 212-213
-
-
Aldred, M.A.1
Vijayakrishnan, J.2
James, V.3
Soubrier, F.4
Gomez-Sanchez, M.A.5
Martensson, G.6
Galie, N.7
Manes, A.8
Corris, P.9
Simonneau, G.10
-
94
-
-
23044504042
-
Increased susceptibility to pulmonary hypertension in heterozygous BMPR2-mutant mice
-
Song, Y.; Jones, J.E.; Beppu, H.; Keaney, J.F., Jr.; Loscalzo, J.; Zhang, Y.Y. Increased susceptibility to pulmonary hypertension in heterozygous BMPR2-mutant mice. Circulation 2005, 112, 553-562.
-
(2005)
Circulation
, vol.112
, pp. 553-562
-
-
Song, Y.1
Jones, J.E.2
Beppu, H.3
Keaney Jr., J.F.4
Loscalzo, J.5
Zhang, Y.Y.6
-
95
-
-
2442570729
-
Proteins associated with type II bone morphogenetic protein receptor (BMPR-II) and identified by two-dimensional gel electrophoresis and mass spectrometry
-
Hassel, S.; Eichner, A.; Yakymovych, M.; Hellman, U.; Knaus, P.; Souchelnytskyi, S. Proteins associated with type II bone morphogenetic protein receptor (BMPR-II) and identified by two-dimensional gel electrophoresis and mass spectrometry. Proteomics 2004, 4, 1346-1358.
-
(2004)
Proteomics
, vol.4
, pp. 1346-1358
-
-
Hassel, S.1
Eichner, A.2
Yakymovych, M.3
Hellman, U.4
Knaus, P.5
Souchelnytskyi, S.6
-
96
-
-
0025181511
-
Effects of H-7 (protein kinase inhibitor) and phorbol ester on aortic strips from spontaneously hypertensive rats
-
Shibata, R.; Morita, S.; Nagai, K.; Miyata, S.; Iwasaki, T. Effects of H-7 (protein kinase inhibitor) and phorbol ester on aortic strips from spontaneously hypertensive rats. Eur. J. Pharmacol. 1990, 175, 261-271.
-
(1990)
Eur. J. Pharmacol.
, vol.175
, pp. 261-271
-
-
Shibata, R.1
Morita, S.2
Nagai, K.3
Miyata, S.4
Iwasaki, T.5
-
97
-
-
0026785836
-
Protein kinase C activity in blood vessels from normotensive and spontaneously hypertensive rats
-
Bazan, E.; Campbell, A.K.; Rapoport, R.M. Protein kinase C activity in blood vessels from normotensive and spontaneously hypertensive rats. Eur. J. Pharmacol. 1992, 227, 343-348.
-
(1992)
Eur. J. Pharmacol.
, vol.227
, pp. 343-348
-
-
Bazan, E.1
Campbell, A.K.2
Rapoport, R.M.3
-
98
-
-
0026457630
-
Gamma-interferon corrects aberrant protein kinase C levels and immunosuppression in the spontaneously hypertensive rat
-
Sauro, M.D.; Hadden, J.W. Gamma-interferon corrects aberrant protein kinase C levels and immunosuppression in the spontaneously hypertensive rat. Int. J. Immunopharmacol. 1992, 14, 1421-1427.
-
(1992)
Int. J. Immunopharmacol.
, vol.14
, pp. 1421-1427
-
-
Sauro, M.D.1
Hadden, J.W.2
-
99
-
-
0030609048
-
2+ sensitivity of contractile elements via protein kinase C in alpha-toxin permeabilized SMA from young spontaneously hypertensive rats
-
2+ sensitivity of contractile elements via protein kinase C in alpha-toxin permeabilized SMA from young spontaneously hypertensive rats. Cardiovasc. Res. 1997, 36, 86-91.
-
(1997)
Cardiovasc. Res.
, vol.36
, pp. 86-91
-
-
Sasajima, H.1
Shima, H.2
Toyoda, Y.3
Kimura, K.4
Yoshikawa, A.5
Hano, T.6
Nishio, I.7
-
100
-
-
0033386579
-
The effects of angiotensin II, endothelin-1, and protein kinase C inhibitor on DNA synthesis and intracellular calcium mobilization in vascular smooth muscle cells from young normotensive and spontaneously hypertensive rats
-
Rosen, B.; Barg, J.; Zimlichman, R. The effects of angiotensin II, endothelin-1, and protein kinase C inhibitor on DNA synthesis and intracellular calcium mobilization in vascular smooth muscle cells from young normotensive and spontaneously hypertensive rats. Am. J. Hypertens. 1999, 12, 1243-1251.
-
(1999)
Am. J. Hypertens.
, vol.12
, pp. 1243-1251
-
-
Rosen, B.1
Barg, J.2
Zimlichman, R.3
-
101
-
-
0025366144
-
Phorbol-12,13-dibutyrate-induced vasoconstriction in vivo: Characterization of response in genetic hypertension
-
Bilder, G.E.; Kasiewski, C.J.; Perrone, M.H. Phorbol-12,13-dibutyrate-induced vasoconstriction in vivo: characterization of response in genetic hypertension. J. Pharmacol. Exp. Ther. 1990, 252, 526-530.
-
(1990)
J. Pharmacol. Exp. Ther.
, vol.252
, pp. 526-530
-
-
Bilder, G.E.1
Kasiewski, C.J.2
Perrone, M.H.3
-
102
-
-
0035006405
-
Gender-related distinctions in protein kinase C activity in rat vascular smooth muscle
-
Kanashiro, C.A.; Khalil, R.A. Gender-related distinctions in protein kinase C activity in rat vascular smooth muscle. Am. J. Physiol. Cell. Physiol. 2001, 280, C34-C45.
-
(2001)
Am. J. Physiol. Cell. Physiol.
, vol.280
-
-
Kanashiro, C.A.1
Khalil, R.A.2
-
103
-
-
0034948793
-
Increased generation of superoxide by angiotensin II in smooth muscle cells from resistance arteries of hypertensive patients: Role of phospholipase D-dependent NAD(P)H oxidase-sensitive pathways
-
Touyz, R.M.; Schiffrin, E.L. Increased generation of superoxide by angiotensin II in smooth muscle cells from resistance arteries of hypertensive patients: role of phospholipase D-dependent NAD(P)H oxidase-sensitive pathways. J. Hypertens. 2001, 19, 1245-1254.
-
(2001)
J. Hypertens.
, vol.19
, pp. 1245-1254
-
-
Touyz, R.M.1
Schiffrin, E.L.2
-
104
-
-
0037217460
-
Alteration of lipids, G proteins, and PKC in cell membranes of elderly hypertensives
-
Escriba, P.V.; Sanchez-Dominguez, J.M.; Alemany, R.; Perona, J.S.; Ruiz-Gutierrez, V. Alteration of lipids, G proteins, and PKC in cell membranes of elderly hypertensives. Hypertension 2003, 41, 176-182.
-
(2003)
Hypertension
, vol.41
, pp. 176-182
-
-
Escriba, P.V.1
Sanchez-Dominguez, J.M.2
Alemany, R.3
Perona, J.S.4
Ruiz-Gutierrez, V.5
-
105
-
-
0028030002
-
Increased protein kinase C and isozyme redistribution in pressure-overload cardiac hypertrophy in the rat
-
Gu, X.; Bishop, S.P. Increased protein kinase C and isozyme redistribution in pressure-overload cardiac hypertrophy in the rat. Circ. Res. 1994, 75, 926-931.
-
(1994)
Circ. Res.
, vol.75
, pp. 926-931
-
-
Gu, X.1
Bishop, S.P.2
-
106
-
-
2942701971
-
Endothelial dysfunction in aortic rings and mesenteric beds isolated from deoxycorticosterone acetate hypertensive rats: Possible involvement of protein kinase C
-
Fatehi-Hassanabad, Z.; Fatehi, M.; Shahidi, M.I. Endothelial dysfunction in aortic rings and mesenteric beds isolated from deoxycorticosterone acetate hypertensive rats: Possible involvement of protein kinase C. Eur. J. Pharmacol. 2004, 494, 199-204.
-
(2004)
Eur. J. Pharmacol.
, vol.494
, pp. 199-204
-
-
Fatehi-Hassanabad, Z.1
Fatehi, M.2
Shahidi, M.I.3
-
107
-
-
0031784604
-
Evidence for the involvement of protein kinase C in depression of endothelium-dependent vascular responses in spontaneously hypertensive rats
-
Soloviev, A.I.; Parshikov, A.V.; Stefanov, A.V. Evidence for the involvement of protein kinase C in depression of endothelium-dependent vascular responses in spontaneously hypertensive rats. J. Vasc. Res. 1998, 35, 325-331.
-
(1998)
J. Vasc. Res.
, vol.35
, pp. 325-331
-
-
Soloviev, A.I.1
Parshikov, A.V.2
Stefanov, A.V.3
-
108
-
-
0029021148
-
Hypertension in mice lacking the gene for endothelial nitric oxide synthase
-
Huang, P.L.; Huang, Z.; Mashimo, H.; Bloch, K.D.; Moskowitz, M.A.; Bevan, J.A.; Fishman, M.C. Hypertension in mice lacking the gene for endothelial nitric oxide synthase. Nature 1995, 377, 239-242.
-
(1995)
Nature
, vol.377
, pp. 239-242
-
-
Huang, P.L.1
Huang, Z.2
Mashimo, H.3
Bloch, K.D.4
Moskowitz, M.A.5
Bevan, J.A.6
Fishman, M.C.7
-
109
-
-
0035947574
-
Coordinated control of endothelial nitric-oxide synthase phosphorylation by protein kinase C and the cAMP-dependent protein kinase
-
Michell, B.J.; Chen, Z.; Tiganis, T.; Stapleton, D.; Katsis, F.; Power, D.A.; Sim, A.T.; Kemp, B.E. Coordinated control of endothelial nitric-oxide synthase phosphorylation by protein kinase C and the cAMP-dependent protein kinase. J. Biol. Chem. 2001, 276, 17625-17628.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 17625-17628
-
-
Michell, B.J.1
Chen, Z.2
Tiganis, T.3
Stapleton, D.4
Katsis, F.5
Power, D.A.6
Sim, A.T.7
Kemp, B.E.8
-
110
-
-
0035827676
-
Phosphorylation of Thr(495) regulates Ca(2+)/calmodulin-dependent endothelial nitric oxide synthase activity
-
Fleming, I.; Fisslthaler, B.; Dimmeler, S.; Kemp, B.E.; Busse, R. Phosphorylation of Thr(495) regulates Ca(2+)/calmodulin-dependent endothelial nitric oxide synthase activity. Circ. Res. 2001, 88, E68-E75.
-
(2001)
Circ. Res.
, vol.88
-
-
Fleming, I.1
Fisslthaler, B.2
Dimmeler, S.3
Kemp, B.E.4
Busse, R.5
-
111
-
-
33847072066
-
Mechanism of endothelial nitric oxide synthase phosphorylation and activation by thrombin
-
Motley, E.D.; Eguchi, K.; Patterson, M.M.; Palmer, P.D.; Suzuki, H.; Eguchi, S. Mechanism of endothelial nitric oxide synthase phosphorylation and activation by thrombin. Hypertension 2007, 49, 577-583.
-
(2007)
Hypertension
, vol.49
, pp. 577-583
-
-
Motley, E.D.1
Eguchi, K.2
Patterson, M.M.3
Palmer, P.D.4
Suzuki, H.5
Eguchi, S.6
-
112
-
-
24744469672
-
PKCalpha activates eNOS and increases arterial blood flow in vivo
-
Partovian, C.; Zhuang, Z.; Moodie, K.; Lin, M.; Ouchi, N.; Sessa, W.C.; Walsh, K.; Simons, M. PKCalpha activates eNOS and increases arterial blood flow in vivo. Circ. Res. 2005, 97, 482-487.
-
(2005)
Circ. Res.
, vol.97
, pp. 482-487
-
-
Partovian, C.1
Zhuang, Z.2
Moodie, K.3
Lin, M.4
Ouchi, N.5
Sessa, W.C.6
Walsh, K.7
Simons, M.8
-
113
-
-
0032482975
-
Superoxide generation by endothelial nitric oxide synthase: The influence of cofactors
-
Vasquez-Vivar, J.; Kalyanaraman, B.; Martasek, P.; Hogg, N.; Masters, B.S.; Karoui, H.; Tordo, P.; Pritchard, K.A., Jr. Superoxide generation by endothelial nitric oxide synthase: The influence of cofactors. Proc. Natl. Acad. Sci. USA 1998, 95, 9220-9225.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 9220-9225
-
-
Vasquez-Vivar, J.1
Kalyanaraman, B.2
Martasek, P.3
Hogg, N.4
Masters, B.S.5
Karoui, H.6
Tordo, P.7
Pritchard Jr., K.A.8
-
114
-
-
0032475865
-
2+/calmodulin-dependent and tetrahydrobiopterin regulatory process
-
2+/calmodulin-dependent and tetrahydrobiopterin regulatory process. J. Biol. Chem. 1998, 273, 25804-25808.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 25804-25808
-
-
Xia, Y.1
Tsai, A.L.2
Berka, V.3
Zweier, J.L.4
-
115
-
-
33745009958
-
Reversal of endothelial nitric oxide synthase uncoupling and up-regulation of endothelial nitric oxide synthase expression lowers blood pressure in hypertensive rats
-
Li, H.; Witte, K.; August, M.; Brausch, I.; Godtel-Armbrust, U.; Habermeier, A.; Closs, E.I.; Oelze, M.; Munzel, T.; Forstermann, U. Reversal of endothelial nitric oxide synthase uncoupling and up-regulation of endothelial nitric oxide synthase expression lowers blood pressure in hypertensive rats. J. Am. Coll. Cardiol. 2006, 47, 2536-2544.
-
(2006)
J. Am. Coll. Cardiol.
, vol.47
, pp. 2536-2544
-
-
Li, H.1
Witte, K.2
August, M.3
Brausch, I.4
Godtel-Armbrust, U.5
Habermeier, A.6
Closs, E.I.7
Oelze, M.8
Munzel, T.9
Forstermann, U.10
-
116
-
-
33645741401
-
Superoxide anion is elevated in sympathetic neurons in DOCA-salt hypertension via activation of NADPH oxidase
-
Dai, X.; Cao, X.; Kreulen, D.L. Superoxide anion is elevated in sympathetic neurons in DOCA-salt hypertension via activation of NADPH oxidase. Am. J. Physiol. Heart Circ. Physiol. 2006, 290, H1019-H1026.
-
(2006)
Am. J. Physiol. Heart Circ. Physiol.
, vol.290
-
-
Dai, X.1
Cao, X.2
Kreulen, D.L.3
-
117
-
-
0037332390
-
Myocardial PKC beta2 and the sensitivity of Na/K-ATPase to marinobufagenin are reduced by cicletanine in Dahl hypertension
-
Fedorova, O.V.; Talan, M.I.; Agalakova, N.I.; Droy-Lefaix, M.T.; Lakatta, E.G.; Bagrov, A.Y. Myocardial PKC beta2 and the sensitivity of Na/K-ATPase to marinobufagenin are reduced by cicletanine in Dahl hypertension. Hypertension 2003, 41, 505-511.
-
(2003)
Hypertension
, vol.41
, pp. 505-511
-
-
Fedorova, O.V.1
Talan, M.I.2
Agalakova, N.I.3
Droy-Lefaix, M.T.4
Lakatta, E.G.5
Bagrov, A.Y.6
-
118
-
-
0037155057
-
Matrix metalloproteinases in vascular remodeling and atherogenesis: The good, the bad, and the ugly
-
Galis, Z.S.; Khatri, J.J. Matrix metalloproteinases in vascular remodeling and atherogenesis: the good, the bad, and the ugly. Circ. Res. 2002, 90, 251-262.
-
(2002)
Circ. Res.
, vol.90
, pp. 251-262
-
-
Galis, Z.S.1
Khatri, J.J.2
-
119
-
-
0037693895
-
Matrix metalloproteinases and tissue inhibitors of metalloproteinases: Structure, function, and biochemistry
-
Visse, R.; Nagase, H. Matrix metalloproteinases and tissue inhibitors of metalloproteinases: structure, function, and biochemistry. Circ. Res. 2003, 92, 827-839.
-
(2003)
Circ. Res.
, vol.92
, pp. 827-839
-
-
Visse, R.1
Nagase, H.2
-
120
-
-
84861816728
-
Matrix metalloproteinase inhibitors as investigative tools in the pathogenesis and management of vascular disease
-
Benjamin, M.M.; Khalil, R.A. Matrix metalloproteinase inhibitors as investigative tools in the pathogenesis and management of vascular disease. Experientia. Supplementum. 2012, 103, 209-279.
-
(2012)
Experientia. Supplementum.
, vol.103
, pp. 209-279
-
-
Benjamin, M.M.1
Khalil, R.A.2
-
123
-
-
33746380241
-
Matrix metalloproteinase-2,-9, and tissue inhibitor of metalloproteinase-1 in patients with hypertension
-
Derosa, G.; D'Angelo, A.; Ciccarelli, L.; Piccinni, M.N.; Pricolo, F.; Salvadeo, S.; Montagna, L.; Gravina, A.; Ferrari, I.; Galli, S.; et al. Matrix metalloproteinase-2,-9, and tissue inhibitor of metalloproteinase-1 in patients with hypertension. Endothelium 2006, 13, 227-231.
-
(2006)
Endothelium
, vol.13
, pp. 227-231
-
-
Derosa, G.1
D'Angelo, A.2
Ciccarelli, L.3
Piccinni, M.N.4
Pricolo, F.5
Salvadeo, S.6
Montagna, L.7
Gravina, A.8
Ferrari, I.9
Galli, S.10
-
124
-
-
0037291886
-
Plasma levels of active extracellular matrix metalloproteinases 2 and 9 in patients with essential hypertension before and after antihypertensive treatment
-
Zervoudaki, A.; Economou, E.; Stefanadis, C.; Pitsavos, C.; Tsioufis, K.; Aggeli, C.; Vasiliadou, K.; Toutouza, M.; Toutouzas, P. Plasma levels of active extracellular matrix metalloproteinases 2 and 9 in patients with essential hypertension before and after antihypertensive treatment. J. Hum. Hypertens. 2003, 17, 119-124.
-
(2003)
J. Hum. Hypertens.
, vol.17
, pp. 119-124
-
-
Zervoudaki, A.1
Economou, E.2
Stefanadis, C.3
Pitsavos, C.4
Tsioufis, K.5
Aggeli, C.6
Vasiliadou, K.7
Toutouza, M.8
Toutouzas, P.9
-
125
-
-
34250827318
-
Role of matrix metalloproteinases in early hypertensive vascular remodeling
-
Flamant, M.; Placier, S.; Dubroca, C.; Esposito, B.; Lopes, I.; Chatziantoniou, C.; Tedgui, A.; Dussaule, J.C.; Lehoux, S. Role of matrix metalloproteinases in early hypertensive vascular remodeling. Hypertension 2007, 50, 212-218.
-
(2007)
Hypertension
, vol.50
, pp. 212-218
-
-
Flamant, M.1
Placier, S.2
Dubroca, C.3
Esposito, B.4
Lopes, I.5
Chatziantoniou, C.6
Tedgui, A.7
Dussaule, J.C.8
Lehoux, S.9
-
126
-
-
0035684166
-
Regulation of extracellular matrix remodeling and MMP-2 activation in cultured rat adrenal medullary endothelial cells
-
Papadimitriou, E.; Waters, C.R.; Manolopoulos, V.G.; Unsworth, B.R.; Maragoudakis, M.E.; Lelkes, P.I. Regulation of extracellular matrix remodeling and MMP-2 activation in cultured rat adrenal medullary endothelial cells. Endothelium 2001, 8, 243-253.
-
(2001)
Endothelium
, vol.8
, pp. 243-253
-
-
Papadimitriou, E.1
Waters, C.R.2
Manolopoulos, V.G.3
Unsworth, B.R.4
Maragoudakis, M.E.5
Lelkes, P.I.6
-
127
-
-
0037418043
-
LOX-1 mediates oxidized low-density lipoprotein-induced expression of matrix metalloproteinases in human coronary artery endothelial cells
-
Li, D.; Liu, L.; Chen, H.; Sawamura, T.; Ranganathan, S.; Mehta, J.L. LOX-1 mediates oxidized low-density lipoprotein-induced expression of matrix metalloproteinases in human coronary artery endothelial cells. Circulation 2003, 107, 612-617.
-
(2003)
Circulation
, vol.107
, pp. 612-617
-
-
Li, D.1
Liu, L.2
Chen, H.3
Sawamura, T.4
Ranganathan, S.5
Mehta, J.L.6
-
129
-
-
33645412144
-
Dietary salt and hypertension: New molecular targets add more spice
-
Khalil, R.A. Dietary salt and hypertension: new molecular targets add more spice. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2006, 290, R509-R513.
-
(2006)
Am. J. Physiol. Regul. Integr. Comp. Physiol.
, vol.290
-
-
Khalil, R.A.1
-
130
-
-
0033845531
-
Altered cardiac endothelin receptors and protein kinase C in deoxycorticosterone-salt hypertensive rats
-
Fareh, J.; Touyz, R.M.; Schiffrin, E.L.; Thibault, G. Altered cardiac endothelin receptors and protein kinase C in deoxycorticosterone-salt hypertensive rats. J. Mol. Cell. Cardiol. 2000, 32, 665-676.
-
(2000)
J. Mol. Cell. Cardiol.
, vol.32
, pp. 665-676
-
-
Fareh, J.1
Touyz, R.M.2
Schiffrin, E.L.3
Thibault, G.4
-
131
-
-
19344374171
-
Mitogen-activated protein kinase contributes to elevated basal tone in aortic smooth muscle from hypertensive rats
-
Kim, J.; Lee, Y.R.; Lee, C.H.; Choi, W.H.; Lee, C.K.; Bae, Y.M.; Cho, S.; Kim, B. Mitogen-activated protein kinase contributes to elevated basal tone in aortic smooth muscle from hypertensive rats. Eur. J. Pharmacol. 2005, 514, 209-215.
-
(2005)
Eur. J. Pharmacol.
, vol.514
, pp. 209-215
-
-
Kim, J.1
Lee, Y.R.2
Lee, C.H.3
Choi, W.H.4
Lee, C.K.5
Bae, Y.M.6
Cho, S.7
Kim, B.8
-
132
-
-
0035092205
-
Endothelin-1 enhances eicosanoids-induced coronary smooth muscle contraction by activating specific protein kinase C isoforms
-
Sirous, Z.N.; Fleming, J.B.; Khalil, R.A. Endothelin-1 enhances eicosanoids-induced coronary smooth muscle contraction by activating specific protein kinase C isoforms. Hypertension 2001, 37, 497-504.
-
(2001)
Hypertension
, vol.37
, pp. 497-504
-
-
Sirous, Z.N.1
Fleming, J.B.2
Khalil, R.A.3
-
133
-
-
0036179702
-
Endothelin-1--induced enhancement of coronary smooth muscle contraction via MAPK-dependent and MAPK-independent [Ca(2+)](i) sensitization pathways
-
Cain, A.E.; Tanner, D.M.; Khalil, R.A. Endothelin-1--induced enhancement of coronary smooth muscle contraction via MAPK-dependent and MAPK-independent [Ca(2+)](i) sensitization pathways. Hypertension 2002, 39, 543-549.
-
(2002)
Hypertension
, vol.39
, pp. 543-549
-
-
Cain, A.E.1
Tanner, D.M.2
Khalil, R.A.3
-
134
-
-
80053539465
-
Modulators of the vascular endothelin receptor in blood pressure regulation and hypertension
-
Khalil, R.A. Modulators of the vascular endothelin receptor in blood pressure regulation and hypertension. Curr. Mol. Pharmacol. 2011, 4, 176-186.
-
(2011)
Curr. Mol. Pharmacol.
, vol.4
, pp. 176-186
-
-
Khalil, R.A.1
-
135
-
-
0029001207
-
Endothelin: Potential role in hypertension and vascular hypertrophy
-
Schiffrin, E.L. Endothelin: potential role in hypertension and vascular hypertrophy. Hypertension 1995, 25, 1135-1143.
-
(1995)
Hypertension
, vol.25
, pp. 1135-1143
-
-
Schiffrin, E.L.1
-
136
-
-
0028709323
-
Modulation of protein kinase C in aorta of spontaneously hypertensive rats with enalapril treatment
-
Kanayama, Y.; Negoro, N.; Okamura, M.; Konishi, Y.; Nishimura, M.; Umetani, N.; Inoue, T.; Takeda, T. Modulation of protein kinase C in aorta of spontaneously hypertensive rats with enalapril treatment. Osaka City Med. J. 1994, 40, 83-97.
-
(1994)
Osaka City Med. J.
, vol.40
, pp. 83-97
-
-
Kanayama, Y.1
Negoro, N.2
Okamura, M.3
Konishi, Y.4
Nishimura, M.5
Umetani, N.6
Inoue, T.7
Takeda, T.8
-
137
-
-
0034051137
-
Renal sodium/calcium exchange; a vasodilator that is defective in salt-sensitive hypertension
-
Bell, P.D.; Mashburn, N.; Unlap, M.T. Renal sodium/calcium exchange; a vasodilator that is defective in salt-sensitive hypertension. Acta. Physiol. Scand. 2000, 168, 209-214.
-
(2000)
Acta. Physiol. Scand.
, vol.168
, pp. 209-214
-
-
Bell, P.D.1
Mashburn, N.2
Unlap, M.T.3
-
138
-
-
0033637387
-
Dopamine-induced translocation of protein kinase C isoforms visualized in renal epithelial cells
-
Nowicki, S.; Kruse, M.S.; Brismar, H.; Aperia, A. Dopamine-induced translocation of protein kinase C isoforms visualized in renal epithelial cells. Am. J. Physiol. Cell. Physiol. 2000, 279, C1812-C1818.
-
(2000)
Am. J. Physiol. Cell. Physiol.
, vol.279
-
-
Nowicki, S.1
Kruse, M.S.2
Brismar, H.3
Aperia, A.4
-
139
-
-
0036223572
-
Dopamine-induced exocytosis of Na, K-ATPase is dependent on activation of protein kinase C-epsilon and-delta
-
Ridge, K.M.; Dada, L.; Lecuona, E.; Bertorello, A.M.; Katz, A.I.; Mochly-Rosen, D.; Sznajder, J.I. Dopamine-induced exocytosis of Na, K-ATPase is dependent on activation of protein kinase C-epsilon and-delta. Mol. Biol. Cell. 2002, 13, 1381-1389.
-
(2002)
Mol. Biol. Cell.
, vol.13
, pp. 1381-1389
-
-
Ridge, K.M.1
Dada, L.2
Lecuona, E.3
Bertorello, A.M.4
Katz, A.I.5
Mochly-Rosen, D.6
Sznajder, J.I.7
-
140
-
-
34248209629
-
Oxidative stress causes renal dopamine D1 receptor dysfunction and hypertension via mechanisms that involve nuclear factor-kappaB and protein kinase C
-
Banday, A.A.; Fazili, F.R.; Lokhandwala, M.F. Oxidative stress causes renal dopamine D1 receptor dysfunction and hypertension via mechanisms that involve nuclear factor-kappaB and protein kinase C. J. Am. Soc. Nephrol. 2007, 18, 1446-1457.
-
(2007)
J. Am. Soc. Nephrol.
, vol.18
, pp. 1446-1457
-
-
Banday, A.A.1
Fazili, F.R.2
Lokhandwala, M.F.3
-
141
-
-
0035467824
-
Expression and distribution of protein kinase C isozymes in brain tissue of spontaneous hypertensive rats
-
Hughes-Darden, C.A.; Wachira, S.J.; Denaro, F.J.; Taylor, C.V.; Brunson, K.J.; Ochillo, R.; Robinson, T.J. Expression and distribution of protein kinase C isozymes in brain tissue of spontaneous hypertensive rats. Cell. Mol. Biol. (Noisy-le-grand) 2001, 47, 1077-1088.
-
(2001)
Cell. Mol. Biol. (Noisy-le-grand)
, vol.47
, pp. 1077-1088
-
-
Hughes-Darden, C.A.1
Wachira, S.J.2
Denaro, F.J.3
Taylor, C.V.4
Brunson, K.J.5
Ochillo, R.6
Robinson, T.J.7
-
142
-
-
34548202734
-
Tyrosine hydroxylase, the rate-limiting enzyme in catecholamine biosynthesis: Discovery of common human genetic variants governing transcription, autonomic activity, and blood pressure in vivo
-
Rao, F.; Zhang, L.; Wessel, J.; Zhang, K.; Wen, G.; Kennedy, B.P.; Rana, B.K.; Das, M.; Rodriguez-Flores, J.L.; Smith, D.W.; et al. Tyrosine hydroxylase, the rate-limiting enzyme in catecholamine biosynthesis: discovery of common human genetic variants governing transcription, autonomic activity, and blood pressure in vivo. Circulation 2007, 116, 993-1006.
-
(2007)
Circulation
, vol.116
, pp. 993-1006
-
-
Rao, F.1
Zhang, L.2
Wessel, J.3
Zhang, K.4
Wen, G.5
Kennedy, B.P.6
Rana, B.K.7
Das, M.8
Rodriguez-Flores, J.L.9
Smith, D.W.10
-
143
-
-
0030743466
-
High glucose concentrations increase endothelial cell permeability via activation of protein kinase C alpha
-
Hempel, A.; Maasch, C.; Heintze, U.; Lindschau, C.; Dietz, R.; Luft, F.C.; Haller, H. High glucose concentrations increase endothelial cell permeability via activation of protein kinase C alpha. Circ. Res. 1997, 81, 363-371.
-
(1997)
Circ. Res.
, vol.81
, pp. 363-371
-
-
Hempel, A.1
Maasch, C.2
Heintze, U.3
Lindschau, C.4
Dietz, R.5
Luft, F.C.6
Haller, H.7
-
144
-
-
0028235884
-
+ antiport activity and gene expression in cultured vascular smooth muscle cells. Role of protein kinase C
-
+ antiport activity and gene expression in cultured vascular smooth muscle cells. Role of protein kinase C. J. Clin. Invest. 1994, 93, 2623-2631.
-
(1994)
J. Clin. Invest.
, vol.93
, pp. 2623-2631
-
-
Williams, B.1
Howard, R.L.2
-
145
-
-
2642592381
-
Antisense DNA downregulates protein kinase C isozymes (beta and alpha) and insulin-stimulated 2-deoxyglucose uptake in rat adipocytes
-
Farese, R.V.; Standaert, M.L.; Ishizuka, T.; Yu, B.; Hernandez, H.; Waldron, C.; Watson, J.; Farese, J.P.; Cooper, D.R.; Wickstrom, E. Antisense DNA downregulates protein kinase C isozymes (beta and alpha) and insulin-stimulated 2-deoxyglucose uptake in rat adipocytes. Antisense Res. Dev. 1991, 1, 35-42.
-
(1991)
Antisense Res. Dev.
, vol.1
, pp. 35-42
-
-
Farese, R.V.1
Standaert, M.L.2
Ishizuka, T.3
Yu, B.4
Hernandez, H.5
Waldron, C.6
Watson, J.7
Farese, J.P.8
Cooper, D.R.9
Wickstrom, E.10
-
146
-
-
13344293711
-
Amelioration of vascular dysfunctions in diabetic rats by an oral PKC beta inhibitor
-
Ishii, H.; Jirousek, M.R.; Koya, D.; Takagi, C.; Xia, P.; Clermont, A.; Bursell, S.E.; Kern, T.S.; Ballas, L.M.; Heath, W.F.; et al. Amelioration of vascular dysfunctions in diabetic rats by an oral PKC beta inhibitor. Science 1996, 272, 728-731.
-
(1996)
Science
, vol.272
, pp. 728-731
-
-
Ishii, H.1
Jirousek, M.R.2
Koya, D.3
Takagi, C.4
Xia, P.5
Clermont, A.6
Bursell, S.E.7
Kern, T.S.8
Ballas, L.M.9
Heath, W.F.10
-
147
-
-
0036796223
-
Cytokines in the pathogenesis of atherosclerosis
-
Young, J.L.; Libby, P.; Schonbeck, U. Cytokines in the pathogenesis of atherosclerosis. Thromb. Haemost. 2002, 88, 554-567.
-
(2002)
Thromb. Haemost.
, vol.88
, pp. 554-567
-
-
Young, J.L.1
Libby, P.2
Schonbeck, U.3
-
148
-
-
11144355152
-
Increased expression of interleukin-1 in coronary artery disease with downregulatory effects of HMG-CoA reductase inhibitors
-
Waehre, T.; Yndestad, A.; Smith, C.; Haug, T.; Tunheim, S.H.; Gullestad, L.; Froland, S.S.; Semb, A.G.; Aukrust, P.; Damas, J.K. Increased expression of interleukin-1 in coronary artery disease with downregulatory effects of HMG-CoA reductase inhibitors. Circulation 2004, 109, 1966-1972.
-
(2004)
Circulation
, vol.109
, pp. 1966-1972
-
-
Waehre, T.1
Yndestad, A.2
Smith, C.3
Haug, T.4
Tunheim, S.H.5
Gullestad, L.6
Froland, S.S.7
Semb, A.G.8
Aukrust, P.9
Damas, J.K.10
-
149
-
-
33646064999
-
Early elevation of interleukin-1beta and interleukin-6 levels after bare or drug-eluting stent implantation in patients with stable angina
-
Sardella, G.; Mariani, P.; D'Alessandro, M.; De Luca, L.; Pierro, M.; Mancone, M.; Porretta, A.; Accapezzato, D.; Fedele, F.; Paroli, M. Early elevation of interleukin-1beta and interleukin-6 levels after bare or drug-eluting stent implantation in patients with stable angina. Thromb. Res. 2006, 117, 659-664.
-
(2006)
Thromb. Res.
, vol.117
, pp. 659-664
-
-
Sardella, G.1
Mariani, P.2
D'Alessandro, M.3
de Luca, L.4
Pierro, M.5
Mancone, M.6
Porretta, A.7
Accapezzato, D.8
Fedele, F.9
Paroli, M.10
-
150
-
-
19744379901
-
Usefulness of high-sensitivity IL-6 measurement for clinical characterization of patients with coronary artery disease
-
Lubrano, V.; Cocci, F.; Battaglia, D.; Papa, A.; Marraccini, P.; Zucchelli, G.C. Usefulness of high-sensitivity IL-6 measurement for clinical characterization of patients with coronary artery disease. J. Clin. Lab. Anal. 2005, 19, 110-114.
-
(2005)
J. Clin. Lab. Anal.
, vol.19
, pp. 110-114
-
-
Lubrano, V.1
Cocci, F.2
Battaglia, D.3
Papa, A.4
Marraccini, P.5
Zucchelli, G.C.6
-
151
-
-
2442670066
-
Increases in interleukin-6 and matrix metalloproteinase-9 in the infarct-related coronary artery of acute myocardial infarction
-
Funayama, H.; Ishikawa, S.E.; Kubo, N.; Katayama, T.; Yasu, T.; Saito, M.; Kawakami, M. Increases in interleukin-6 and matrix metalloproteinase-9 in the infarct-related coronary artery of acute myocardial infarction. Circ. J. 2004, 68, 451-454.
-
(2004)
Circ. J.
, vol.68
, pp. 451-454
-
-
Funayama, H.1
Ishikawa, S.E.2
Kubo, N.3
Katayama, T.4
Yasu, T.5
Saito, M.6
Kawakami, M.7
-
152
-
-
33645744262
-
Angiotensin II hypertension is attenuated in interleukin-6 knockout mice
-
Lee, D.L.; Sturgis, L.C.; Labazi, H.; Osborne, J.B., Jr.; Fleming, C.; Pollock, J.S.; Manhiani, M.; Imig, J.D.; Brands, M.W. Angiotensin II hypertension is attenuated in interleukin-6 knockout mice. Am. J. Physiol. Heart Circ. Physiol. 2006, 290, H935-H940.
-
(2006)
Am. J. Physiol. Heart Circ. Physiol.
, vol.290
-
-
Lee, D.L.1
Sturgis, L.C.2
Labazi, H.3
Osborne Jr., J.B.4
Fleming, C.5
Pollock, J.S.6
Manhiani, M.7
Imig, J.D.8
Brands, M.W.9
-
153
-
-
0034117180
-
Chronic hypoxia induces exaggerated growth responses in pulmonary artery adventitial fibroblasts: Potential contribution of specific protein kinase c isozymes
-
Das, M.; Dempsey, E.C.; Bouchey, D.; Reyland, M.E.; Stenmark, K.R. Chronic hypoxia induces exaggerated growth responses in pulmonary artery adventitial fibroblasts: potential contribution of specific protein kinase c isozymes. Am. J. Respir. Cell. Mol. Biol. 2000, 22, 15-25.
-
(2000)
Am. J. Respir. Cell. Mol. Biol.
, vol.22
, pp. 15-25
-
-
Das, M.1
Dempsey, E.C.2
Bouchey, D.3
Reyland, M.E.4
Stenmark, K.R.5
-
154
-
-
0037378367
-
Protein kinase C-epsilon-null mice have decreased hypoxic pulmonary vasoconstriction
-
Littler, C.M.; Morris, K.G., Jr.; Fagan, K.A.; McMurtry, I.F.; Messing, R.O.; Dempsey, E.C. Protein kinase C-epsilon-null mice have decreased hypoxic pulmonary vasoconstriction. Am. J. Physiol. Heart Circ. Physiol. 2003, 284, H1321-H1331.
-
(2003)
Am. J. Physiol. Heart Circ. Physiol.
, vol.284
-
-
Littler, C.M.1
Morris Jr., K.G.2
Fagan, K.A.3
McMurtry, I.F.4
Messing, R.O.5
Dempsey, E.C.6
-
155
-
-
33947585368
-
Current drug targets and future therapy of pulmonary arterial hypertension
-
Ito, T.; Ozawa, K.; Shimada, K. Current drug targets and future therapy of pulmonary arterial hypertension. Curr. Med. Chem. 2007, 14, 719-733.
-
(2007)
Curr. Med. Chem.
, vol.14
, pp. 719-733
-
-
Ito, T.1
Ozawa, K.2
Shimada, K.3
-
156
-
-
34249849505
-
Pulmonary arterial hypertension: Current therapeutic strategies
-
Puri, A.; McGoon, M.D.; Kushwaha, S.S. Pulmonary arterial hypertension: current therapeutic strategies. Nat. Clin. Pract. Cardiovasc. Med. 2007, 4, 319-329.
-
(2007)
Nat. Clin. Pract. Cardiovasc. Med.
, vol.4
, pp. 319-329
-
-
Puri, A.1
McGoon, M.D.2
Kushwaha, S.S.3
-
157
-
-
34547619198
-
Vasoconstrictor effect of endothelin-1 on hypertensive pulmonary arterial smooth muscle involves Rho-kinase and protein kinase C
-
Barman, S.A. Vasoconstrictor effect of endothelin-1 on hypertensive pulmonary arterial smooth muscle involves Rho-kinase and protein kinase C. Am. J. Physiol. Lung Cell. Mol. Physiol. 2007, 293, L472-L479.
-
(2007)
Am. J. Physiol. Lung Cell. Mol. Physiol.
, vol.293
-
-
Barman, S.A.1
-
158
-
-
0036333677
-
Vascular mechanisms of increased arterial pressure in preeclampsia: Lessons from animal models
-
Khalil, R.A.; Granger, J.P. Vascular mechanisms of increased arterial pressure in preeclampsia: Lessons from animal models. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2002, 283, R29-R45.
-
(2002)
Am. J. Physiol. Regul. Integr. Comp. Physiol.
, vol.283
-
-
Khalil, R.A.1
Granger, J.P.2
-
159
-
-
77950643725
-
Risk factors and mediators of the vascular dysfunction associated with hypertension in pregnancy
-
Sheppard, S.J.; Khalil, R.A. Risk factors and mediators of the vascular dysfunction associated with hypertension in pregnancy. Cardiovasc. Hematol. Disord. Drug Targets 2010, 10, 33-52.
-
(2010)
Cardiovasc. Hematol. Disord. Drug Targets
, vol.10
, pp. 33-52
-
-
Sheppard, S.J.1
Khalil, R.A.2
-
160
-
-
0025728848
-
Protein kinase C in uterine and systemic arteries during ovarian cycle and pregnancy
-
Magness, R.R.; Rosenfeld, C.R.; Carr, B.R. Protein kinase C in uterine and systemic arteries during ovarian cycle and pregnancy. Am. J. Physiol. 1991, 260, E464-E470.
-
(1991)
Am. J. Physiol.
, vol.260
-
-
Magness, R.R.1
Rosenfeld, C.R.2
Carr, B.R.3
-
161
-
-
0034012138
-
Pregnancy-associated reduction in vascular protein kinase C activity rebounds during inhibition of NO synthesis
-
Kanashiro, C.A.; Cockrell, K.L.; Alexander, B.T.; Granger, J.P.; Khalil, R.A. Pregnancy-associated reduction in vascular protein kinase C activity rebounds during inhibition of NO synthesis. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2000, 278, R295-R303.
-
(2000)
Am. J. Physiol. Regul. Integr. Comp. Physiol.
, vol.278
-
-
Kanashiro, C.A.1
Cockrell, K.L.2
Alexander, B.T.3
Granger, J.P.4
Khalil, R.A.5
-
162
-
-
0032753834
-
Ca(2+)-insensitive vascular protein kinase C during pregnancy and NOS inhibition
-
Kanashiro, C.A.; Alexander, B.T.; Granger, J.P.; Khalil, R.A. Ca(2+)-insensitive vascular protein kinase C during pregnancy and NOS inhibition. Hypertension 1999, 34, 924-930.
-
(1999)
Hypertension
, vol.34
, pp. 924-930
-
-
Kanashiro, C.A.1
Alexander, B.T.2
Granger, J.P.3
Khalil, R.A.4
-
163
-
-
0031917998
-
Enhanced vascular reactivity during inhibition of nitric oxide synthesis in pregnant rats
-
Khalil, R.A.; Crews, J.K.; Novak, J.; Kassab, S.; Granger, J.P. Enhanced vascular reactivity during inhibition of nitric oxide synthesis in pregnant rats. Hypertension 1998, 31, 1065-1069.
-
(1998)
Hypertension
, vol.31
, pp. 1065-1069
-
-
Khalil, R.A.1
Crews, J.K.2
Novak, J.3
Kassab, S.4
Granger, J.P.5
-
165
-
-
0032924922
-
Patients with preeclampsia develop agonistic autoantibodies against the angiotensin AT1 receptor
-
Wallukat, G.; Homuth, V.; Fischer, T.; Lindschau, C.; Horstkamp, B.; Jupner, A.; Baur, E.; Nissen, E.; Vetter, K.; Neichel, D.; et al. Patients with preeclampsia develop agonistic autoantibodies against the angiotensin AT1 receptor. J. Clin. Invest. 1999, 103, 945-952.
-
(1999)
J. Clin. Invest.
, vol.103
, pp. 945-952
-
-
Wallukat, G.1
Homuth, V.2
Fischer, T.3
Lindschau, C.4
Horstkamp, B.5
Jupner, A.6
Baur, E.7
Nissen, E.8
Vetter, K.9
Neichel, D.10
-
166
-
-
0028174929
-
Tumor necrosis factor-alpha is elevated in plasma and amniotic fluid of patients with severe preeclampsia
-
discussion 1757-1759
-
Kupferminc, M.J.; Peaceman, A.M.; Wigton, T.R.; Rehnberg, K.A.; Socol, M.L. Tumor necrosis factor-alpha is elevated in plasma and amniotic fluid of patients with severe preeclampsia. Am. J. Obstet. Gynecol. 1994, 170, 1752-1757, discussion 1757-1759.
-
(1994)
Am. J. Obstet. Gynecol.
, vol.170
, pp. 1752-1757
-
-
Kupferminc, M.J.1
Peaceman, A.M.2
Wigton, T.R.3
Rehnberg, K.A.4
Socol, M.L.5
-
167
-
-
0028928129
-
Interleukin-6, tumour necrosis factor and soluble tumour necrosis factor receptors in women with pre-eclampsia
-
Vince, G.S.; Starkey, P.M.; Austgulen, R.; Kwiatkowski, D.; Redman, C.W. Interleukin-6, tumour necrosis factor and soluble tumour necrosis factor receptors in women with pre-eclampsia. Br. J. Obstet. Gynaecol. 1995, 102, 20-25.
-
(1995)
Br. J. Obstet. Gynaecol.
, vol.102
, pp. 20-25
-
-
Vince, G.S.1
Starkey, P.M.2
Austgulen, R.3
Kwiatkowski, D.4
Redman, C.W.5
-
168
-
-
0030935503
-
Placental cytokines and the pathogenesis of preeclampsia
-
Conrad, K.P.; Benyo, D.F. Placental cytokines and the pathogenesis of preeclampsia. Am. J. Reprod. Immunol. 1997, 37, 240-249.
-
(1997)
Am. J. Reprod. Immunol.
, vol.37
, pp. 240-249
-
-
Conrad, K.P.1
Benyo, D.F.2
-
169
-
-
0032213893
-
Plasma tumor necrosis factor-alpha soluble receptor p55 (sTNFp55) concentrations in eclamptic, preeclamptic and normotensive pregnant Zimbabwean women
-
Williams, M.A.; Mahomed, K.; Farrand, A.; Woelk, G.B.; Mudzamiri, S.; Madzime, S.; King, I.B.; McDonald, G.B. Plasma tumor necrosis factor-alpha soluble receptor p55 (sTNFp55) concentrations in eclamptic, preeclamptic and normotensive pregnant Zimbabwean women. J. Reprod. Immunol. 1998, 40, 159-173.
-
(1998)
J. Reprod. Immunol.
, vol.40
, pp. 159-173
-
-
Williams, M.A.1
Mahomed, K.2
Farrand, A.3
Woelk, G.B.4
Mudzamiri, S.5
Madzime, S.6
King, I.B.7
McDonald, G.B.8
-
170
-
-
38049161796
-
Inflammatory cytokines in the pathophysiology of hypertension during preeclampsia
-
LaMarca, B.D.; Ryan, M.J.; Gilbert, J.S.; Murphy, S.R.; Granger, J.P. Inflammatory cytokines in the pathophysiology of hypertension during preeclampsia. Curr. Hypertens. Rep. 2007, 9, 480-485.
-
(2007)
Curr. Hypertens. Rep.
, vol.9
, pp. 480-485
-
-
LaMarca, B.D.1
Ryan, M.J.2
Gilbert, J.S.3
Murphy, S.R.4
Granger, J.P.5
-
171
-
-
0034970684
-
Expression of inflammatory cytokines in placentas from women with preeclampsia
-
Benyo, D.F.; Smarason, A.; Redman, C.W.; Sims, C.; Conrad, K.P. Expression of inflammatory cytokines in placentas from women with preeclampsia. J. Clin. Endocrinol. Metab. 2001, 86, 2505-2512.
-
(2001)
J. Clin. Endocrinol. Metab.
, vol.86
, pp. 2505-2512
-
-
Benyo, D.F.1
Smarason, A.2
Redman, C.W.3
Sims, C.4
Conrad, K.P.5
-
172
-
-
0036081551
-
Reduced endothelial NO-cGMP vascular relaxation pathway during TNF-alpha-induced hypertension in pregnant rats
-
Davis, J.R.; Giardina, J.B.; Green, G.M.; Alexander, B.T.; Granger, J.P.; Khalil, R.A. Reduced endothelial NO-cGMP vascular relaxation pathway during TNF-alpha-induced hypertension in pregnant rats. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2002, 282, R390-R399.
-
(2002)
Am. J. Physiol. Regul. Integr. Comp. Physiol.
, vol.282
-
-
Davis, J.R.1
Giardina, J.B.2
Green, G.M.3
Alexander, B.T.4
Granger, J.P.5
Khalil, R.A.6
-
173
-
-
0842289883
-
Reduced endothelial NO-cGMP-mediated vascular relaxation and hypertension in IL-6-infused pregnant rats
-
Orshal, J.M.; Khalil, R.A. Reduced endothelial NO-cGMP-mediated vascular relaxation and hypertension in IL-6-infused pregnant rats. Hypertension 2004, 43, 434-444.
-
(2004)
Hypertension
, vol.43
, pp. 434-444
-
-
Orshal, J.M.1
Khalil, R.A.2
-
174
-
-
0036334223
-
TNF-alpha enhances contraction and inhibits endothelial NO-cGMP relaxation in systemic vessels of pregnant rats
-
Giardina, J.B.; Green, G.M.; Cockrell, K.L.; Granger, J.P.; Khalil, R.A. TNF-alpha enhances contraction and inhibits endothelial NO-cGMP relaxation in systemic vessels of pregnant rats. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2002, 283, R130-R143.
-
(2002)
Am. J. Physiol. Regul. Integr. Comp. Physiol.
, vol.283
-
-
Giardina, J.B.1
Green, G.M.2
Cockrell, K.L.3
Granger, J.P.4
Khalil, R.A.5
-
175
-
-
2442706712
-
Interleukin-6 impairs endothelium-dependent NO-cGMP-mediated relaxation and enhances contraction in systemic vessels of pregnant rats
-
Orshal, J.M.; Khalil, R.A. Interleukin-6 impairs endothelium-dependent NO-cGMP-mediated relaxation and enhances contraction in systemic vessels of pregnant rats. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2004, 286, R1013-R1023.
-
(2004)
Am. J. Physiol. Regul. Integr. Comp. Physiol.
, vol.286
-
-
Orshal, J.M.1
Khalil, R.A.2
-
176
-
-
36448996940
-
Hypertension produced by reduced uterine perfusion in pregnant rats is associated with increased soluble fms-like tyrosine kinase-1 expression
-
Gilbert, J.S.; Babcock, S.A.; Granger, J.P. Hypertension produced by reduced uterine perfusion in pregnant rats is associated with increased soluble fms-like tyrosine kinase-1 expression. Hypertension 2007, 50, 1142-1147.
-
(2007)
Hypertension
, vol.50
, pp. 1142-1147
-
-
Gilbert, J.S.1
Babcock, S.A.2
Granger, J.P.3
-
177
-
-
59849106572
-
Hypertension produced by placental ischemia in pregnant rats is associated with increased soluble endoglin expression
-
Gilbert, J.S.; Gilbert, S.A.; Arany, M.; Granger, J.P. Hypertension produced by placental ischemia in pregnant rats is associated with increased soluble endoglin expression. Hypertension 2009, 53, 399-403.
-
(2009)
Hypertension
, vol.53
, pp. 399-403
-
-
Gilbert, J.S.1
Gilbert, S.A.2
Arany, M.3
Granger, J.P.4
-
178
-
-
0034000644
-
Cicletanine reverses vasoconstriction induced by the endogenous sodium pump ligand, marinobufagenin, via a protein kinase C dependent mechanism
-
Bagrov, A.Y.; Dmitrieva, R.I.; Dorofeeva, N.A.; Fedorova, O.V.; Lopatin, D.A.; Lakatta, E.G.; Droy-Lefaix, M.T. Cicletanine reverses vasoconstriction induced by the endogenous sodium pump ligand, marinobufagenin, via a protein kinase C dependent mechanism. J. Hypertens. 2000, 18, 209-215.
-
(2000)
J. Hypertens.
, vol.18
, pp. 209-215
-
-
Bagrov, A.Y.1
Dmitrieva, R.I.2
Dorofeeva, N.A.3
Fedorova, O.V.4
Lopatin, D.A.5
Lakatta, E.G.6
Droy-Lefaix, M.T.7
-
179
-
-
0037423816
-
Activation of RhoA and inhibition of myosin phosphatase as important components in hypertension in vascular smooth muscle
-
Seko, T.; Ito, M.; Kureishi, Y.; Okamoto, R.; Moriki, N.; Onishi, K.; Isaka, N.; Hartshorne, D.J.; Nakano, T. Activation of RhoA and inhibition of myosin phosphatase as important components in hypertension in vascular smooth muscle. Circ. Res. 2003, 92, 411-418.
-
(2003)
Circ. Res.
, vol.92
, pp. 411-418
-
-
Seko, T.1
Ito, M.2
Kureishi, Y.3
Okamoto, R.4
Moriki, N.5
Onishi, K.6
Isaka, N.7
Hartshorne, D.J.8
Nakano, T.9
-
180
-
-
0029988355
-
Up-regulation of intracellular signalling pathways may play a central pathogenic role in hypertension, atherogenesis, insulin resistance, and cancer promotion-The PKC syndrome
-
McCarty, M.F. Up-regulation of intracellular signalling pathways may play a central pathogenic role in hypertension, atherogenesis, insulin resistance, and cancer promotion-The "PKC syndrome". Med. Hypotheses 1996, 46, 191-221.
-
(1996)
Med. Hypotheses
, vol.46
, pp. 191-221
-
-
McCarty, M.F.1
-
181
-
-
58249089758
-
Effect of ruboxistaurin on the visual acuity decline associated with long-standing diabetic macular edema
-
Davis, M.D.; Sheetz, M.J.; Aiello, L.P.; Milton, R.C.; Danis, R.P.; Zhi, X.; Girach, A.; Jimenez, M.C.; Vignati, L. Effect of ruboxistaurin on the visual acuity decline associated with long-standing diabetic macular edema. Invest. Ophthalmol. Vis. Sci. 2009, 50, 1-4.
-
(2009)
Invest. Ophthalmol. Vis. Sci.
, vol.50
, pp. 1-4
-
-
Davis, M.D.1
Sheetz, M.J.2
Aiello, L.P.3
Milton, R.C.4
Danis, R.P.5
Zhi, X.6
Girach, A.7
Jimenez, M.C.8
Vignati, L.9
-
182
-
-
80055100383
-
Oral protein kinase C beta inhibition using ruboxistaurin: Efficacy, safety, and causes of vision loss among 813 patients (1,392 eyes) with diabetic retinopathy in the protein kinase C beta inhibitor-diabetic retinopathy study and the protein kinase C beta inhibitor-diabetic retinopathy study 2
-
Aiello, L.P.; Vignati, L.; Sheetz, M.J.; Zhi, X.; Girach, A.; Davis, M.D.; Wolka, A.M.; Shahri, N.; Milton, R.C. Oral protein kinase C beta inhibition using ruboxistaurin: efficacy, safety, and causes of vision loss among 813 patients (1,392 eyes) with diabetic retinopathy in the protein kinase C beta inhibitor-diabetic retinopathy study and the protein kinase C beta inhibitor-diabetic retinopathy study 2. Retina 2011, 31, 2084-2094.
-
(2011)
Retina
, vol.31
, pp. 2084-2094
-
-
Aiello, L.P.1
Vignati, L.2
Sheetz, M.J.3
Zhi, X.4
Girach, A.5
Davis, M.D.6
Wolka, A.M.7
Shahri, N.8
Milton, R.C.9
-
183
-
-
25844456960
-
Ruboxistaurin, a protein kinase C beta inhibitor, as an emerging treatment for diabetes microvascular complications
-
Joy, S.V.; Scates, A.C.; Bearelly, S.; Dar, M.; Taulien, C.A.; Goebel, J.A.; Cooney, M.J. Ruboxistaurin, a protein kinase C beta inhibitor, as an emerging treatment for diabetes microvascular complications. Ann. Pharmacother. 2005, 39, 1693-1699.
-
(2005)
Ann. Pharmacother.
, vol.39
, pp. 1693-1699
-
-
Joy, S.V.1
Scates, A.C.2
Bearelly, S.3
Dar, M.4
Taulien, C.A.5
Goebel, J.A.6
Cooney, M.J.7
|