Evidence for the involvement of protein kinase C in depression of endothelium-dependent vascular responses in spontaneously hypertensive rats

Journal of Vascular Research

Volumn 35, Issue 5, 1998, Pages 325-331

  Soloviev, A I ^a   Parshikov, A V ^a   Stefanov, A V ^a  

^a STATE INSTITUTION NATIONAL RESEARCH CENTER FOR RADIATION MEDICINE OF THE NATIONAL ACADEMY OF MEDICAL SCIENCES OF UKRAINE   (Ukraine)

Author keywords

Hypertension; NO release; PKC activity; Sensitivity to NO; Smooth muscle

Indexed keywords

ENDOTHELIUM DERIVED RELAXING FACTOR; NITRIC OXIDE; PROTEIN KINASE C;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA; ARTICLE; BLOOD VESSEL REACTIVITY; CONTROLLED STUDY; ENZYME ACTIVITY; ESSENTIAL HYPERTENSION; NONHUMAN; PRIORITY JOURNAL; RAT; SPONTANEOUSLY HYPERTENSIVE RAT; VASCULAR ENDOTHELIUM; VASCULAR SMOOTH MUSCLE;

1-(5-ISOQUINOLINESULFONYL)-2-METHYLPIPERAZINE; ACETYLCHOLINE; ALKALOIDS; ANIMALS; AORTA, THORACIC; BENZOPHENANTHRIDINES; ENDOTHELIUM, VASCULAR; ENZYME INHIBITORS; HYPERTENSION; NITRIC OXIDE; NOREPINEPHRINE; PHENANTHRIDINES; PROTEIN KINASE C; RATS; RATS, INBRED SHR; RATS, INBRED WKY; VASODILATION;

EID: 0031784604     PISSN: 10181172     EISSN: None     Source Type: Journal    
DOI: 10.1159/000025602     Document Type: Article

References (23)

1. Palmer RM, Feridge AG, Moncada S: Nitric oxide release accounts for the biological activity of endothelium derived relaxing factor. Nature 1987;327:524-526.
2. Chen G, Yamamoto Y, Miva K, Suzuki H: Hyperpolarization of arterial smooth muscle induced by endothelial humoral substances. Am J Physiol 1991;260:H1888-H1992.
3. Konishi M, Su C: Role of endothelium in dilator responses of spontaneously hypertensive rat arteries. Hypertension 1983;5:881-886.
4. Winquist RJ, Bunting PB, Baskin EP, Wallace AA: Decreased endothelium-dependent relaxation in New Zealand genetic hypertensive rats. J Hypertens 1984;2:541-545.
5. De Mey JG, Gray SD: Endothelium-dependent reactivity in resistance vessels. Prog Appl Microcirc 1985;8:181-187.
6. Takata Y, Koga T, Kobayashi K: Decrease in endothelium-dependent hypotension in spontaneously hypertensive rats. Jpn Circ J 1990; 54:183-191.
7. Lusher TF, Vanhoutte PM: Endothelium-dependent contraction to acethylcholine in the aorta of the spontaneously hypertensive rat. Hypertension 1986;8:344-348.
8. Cheng JB, Shibata S: Vascular relaxation in spontaneously hypertensive rat. J Cardiovasc Pharmacol 1981;3:1126-1140.
9. Muracawa K, Kohno M, Yasunari K, et al: Possible involvement of protein kinase C in the maintenance of hypertension in spontaneously hypertensive rats. J Hypertens 1988;6:157-159.
10. Soloviev AI, Bershtein SA: The contractile apparatus in vascular smooth cells of spontaneously hypertensive rats possess increased calcium sensitivity: The possible role of protein kinase C. J Hypertens 1992;10:131-136.
11. Rybanyi GM, Lorenz RR, Vanhoutte PM: Bioassay of endothelium-derived relaxing factor(s): Inactivation by catecholamines. Am J Physiol 1985;249:H95-H101.
12. Fabiato A, Fabiato F: Calculator programs for competing the composition of the solutions containing multiple metals and ligands used for experiments in skinned smooth muscle cells. J Physiol (Lond) 1979;75:463-505.
13. 2 system. Anal Chem 1993;65:1794-1799.
14. Ignarro L: Biological actions and properties of endothelium-derived nitric oxide formed and released from artery and vein. Circ Res 1989; 65:1-21.
15. Rapoport RM: Cyclic guanosine monophosphate inhibition of contraction may be mediated through inhibition of phosphatidylinositol hydrolysis in rat aorta. Circ Res 1986;58: 407-410.
16. Fiscus RR: Molecular mechanisms of endothelium-mediated vasodilation. Semin Thromb Hemost 1988;14(suppl 1):12-22.
17. Soloviev AI, Braquet P: Platelet-activating factor - a potent endogenous mediator responsible for coronary vasospasm. News Physiol Sci 1992;7:166-172.
18. Soloviev AI, Stefanov AV, Bazilyuk OV, Sagach VF: Phospholipid vesicles (liposomes) restore endothelium-dependent cholinergic relaxation in thoracic aorta from spontaneously hypertensive rats. J Hypertens 1993;11:623-627.
19. Cabot M, Welsh C, Cao H, Chabbott H: The phosphatidylcholine pathway of diacylglycerol formation stimulated by phorbol diester occurs via phospholipase D activation. FEBS Lett 1988;233:153-157.
20. Cox R, Tulenko T: Altered excitation-contraction coupling in hypertension: Role of plasma membrane phospholipids and ion channels: in Moreland R (ed): Regulation of Smooth Muscle Contraction. New York, Plenum Press, 1991, pp 291-302.
21. Bassenge E, Busse R: Endothelial modulation of coronary tone. Prog Cardiovasc Dis 1988; 30:349-380.
22. De Nucci G, Gryglewski RJ, Warner TD, Vane JR: Receptor mediated release of endothelium-derived relaxing factor and prostacyclin from bovine aortic endothelial cells is coupled. Proc Natl Acad Sci USA 1988;85:2334-2338.
23. Hirata K, Kuroda R, Sakoda T, Katayama M, Inoue N, Suematsu M, Kawashima S, Yokoyama M: Inhibition of endothelial nitric oxide synthase activity by protein kinase C. Hypertension 1995;25:180-185.