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Volumn 97, Issue 9, 1998, Pages 851-856

Selective defect in nitric oxide synthesis may explain the impaired endothelium-dependent vasodilation in patients with essential hypertension

Author keywords

Acetylcholine; Hypertension; Nitric oxide; Receptors, adrenergic, beta; Signal transduction

Indexed keywords

ACETYLCHOLINE; CALCIUM; ISOPRENALINE; N(G) METHYLARGININE; NITRIC OXIDE; NITRIC OXIDE DONOR; NITRIC OXIDE SYNTHASE; NITROPRUSSIDE SODIUM; PHOSPHATIDYLINOSITOL;

EID: 0032502319     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.97.9.851     Document Type: Article
Times cited : (144)

References (36)
  • 1
    • 0025283892 scopus 로고
    • Abnormal endothelium-dependent relaxation in patients with essential hypertension
    • Panza JA, Quyyumi AA, Brush JE Jr, Epstein SE. Abnormal endothelium-dependent relaxation in patients with essential hypertension. N Engl J Med. 1990;323:22-27.
    • (1990) N Engl J Med , vol.323 , pp. 22-27
    • Panza, J.A.1    Quyyumi, A.A.2    Brush J.E., Jr.3    Epstein, S.E.4
  • 2
    • 0025300333 scopus 로고
    • Indirect evidence for release of endothelium-derived relaxing factor in human forearm circulation in vivo
    • Linder L, Kiowski W, Buhler FR, Luscher TF. Indirect evidence for release of endothelium-derived relaxing factor in human forearm circulation in vivo. Circulation. 1990;81:1762-1767.
    • (1990) Circulation , vol.81 , pp. 1762-1767
    • Linder, L.1    Kiowski, W.2    Buhler, F.R.3    Luscher, T.F.4
  • 4
    • 0027245468 scopus 로고
    • Vasodilation to acetylcholine in primary and secondary forms of human hypertension
    • Taddei S, Virdis A, Mattei P, Salvetti A. Vasodilation to acetylcholine in primary and secondary forms of human hypertension. Hypertension. 1993; 21:929-933.
    • (1993) Hypertension , vol.21 , pp. 929-933
    • Taddei, S.1    Virdis, A.2    Mattei, P.3    Salvetti, A.4
  • 5
    • 0026705075 scopus 로고
    • g-monomethyl-L-arginine in patients with hypertension: The nitric oxide dilator mechanism appears abnormal
    • g-monomethyl-L-arginine in patients with hypertension: the nitric oxide dilator mechanism appears abnormal. J Hypertens. 1992;10:1025-1031.
    • (1992) J Hypertens , vol.10 , pp. 1025-1031
    • Calver, A.1    Collier, J.2    Moncada, S.3    Vallance, P.4
  • 6
    • 0027161713 scopus 로고
    • Role of endothelium-derived nitric oxide in the abnormal endothelium-dependent vascular relaxation in patients with essential hypertension
    • Panza JA, Casino PR, Kilcoyne CM, Quyyumi AA. Role of endothelium-derived nitric oxide in the abnormal endothelium-dependent vascular relaxation in patients with essential hypertension. Circulation. 1993;87: 1468-1474.
    • (1993) Circulation , vol.87 , pp. 1468-1474
    • Panza, J.A.1    Casino, P.R.2    Kilcoyne, C.M.3    Quyyumi, A.A.4
  • 7
    • 0028275313 scopus 로고
    • Impaired endothelium-dependent vasodilation in patients with essential hypertension: Evidence that the abnormality is not at the muscarinic receptor level
    • Panza JA, Casino PR, Kilcoyne CM, Quyyumi AA. Impaired endothelium-dependent vasodilation in patients with essential hypertension: evidence that the abnormality is not at the muscarinic receptor level. J Am Coll Cardiol. 1994;23:1610-1616.
    • (1994) J Am Coll Cardiol , vol.23 , pp. 1610-1616
    • Panza, J.A.1    Casino, P.R.2    Kilcoyne, C.M.3    Quyyumi, A.A.4
  • 8
    • 0028918698 scopus 로고
    • Impaired endothelium-dependent vasodilation in patients with essential hypertension: Evidence that nitric oxide abnormality is not localized to a single signal transduction pathway
    • Panza JA, Garcia CE, Kilcoyne CM, Quyyumi AA, Cannon RO III, Impaired endothelium-dependent vasodilation in patients with essential hypertension: evidence that nitric oxide abnormality is not localized to a single signal transduction pathway. Circulation. 1995;91:1732-1738.
    • (1995) Circulation , vol.91 , pp. 1732-1738
    • Panza, J.A.1    Garcia, C.E.2    Kilcoyne, C.M.3    Quyyumi, A.A.4    Cannon R.O. III5
  • 9
    • 0030827912 scopus 로고    scopus 로고
    • Decreased vasodilator response to isoproterenol during nitric oxide inhibition in humans
    • Cardillo C, Kilcoyne CM, Quyyumi AA, Cannon RO III, Panza JA. Decreased vasodilator response to isoproterenol during nitric oxide inhibition in humans. Hypertension. 1997;30:918-921.
    • (1997) Hypertension , vol.30 , pp. 918-921
    • Cardillo, C.1    Kilcoyne, C.M.2    Quyyumi, A.A.3    Cannon R.O. III4    Panza, J.A.5
  • 10
    • 0030888528 scopus 로고    scopus 로고
    • Effects of inhibition of the L-arginine/nitric oxide pathway on vasodilation caused by β-adrenergic agonists in human forearm
    • Dawes M, Chowienczyk PJ, Ritter JM. Effects of inhibition of the L-arginine/nitric oxide pathway on vasodilation caused by β-adrenergic agonists in human forearm. Circulation. 1997;95:2293-2297.
    • (1997) Circulation , vol.95 , pp. 2293-2297
    • Dawes, M.1    Chowienczyk, P.J.2    Ritter, J.M.3
  • 11
    • 0026806047 scopus 로고
    • Novel signal transduction pathway mediating endothelium-dependent β-adrenoceptor vasorelaxation in rat thoracic aorta
    • Gray DW, Marshall I. Novel signal transduction pathway mediating endothelium-dependent β-adrenoceptor vasorelaxation in rat thoracic aorta. Br J Pharmacol. 1992;107:684-690.
    • (1992) Br J Pharmacol , vol.107 , pp. 684-690
    • Gray, D.W.1    Marshall, I.2
  • 12
    • 0029910049 scopus 로고    scopus 로고
    • A beta-adrenoceptor agonist evokes a nitric oxide-cGMP relaxation mechanism modulated by adenylyl cyclase in rat aorta: Halothane does not inhibit this mechanism
    • Iranami H, Hatano Y, Tsukiyama Y, Maeda H, Mizumoto K. A beta-adrenoceptor agonist evokes a nitric oxide-cGMP relaxation mechanism modulated by adenylyl cyclase in rat aorta: halothane does not inhibit this mechanism. Anesthesiology. 1996;85:1129-1138.
    • (1996) Anesthesiology , vol.85 , pp. 1129-1138
    • Iranami, H.1    Hatano, Y.2    Tsukiyama, Y.3    Maeda, H.4    Mizumoto, K.5
  • 13
    • 0023748446 scopus 로고
    • Hyperpolarization and increased free calcium in acetylcholine-stimulated endothelial cells
    • Busse R, Fichtner H, Luckhoff A, Kohlhardt M. Hyperpolarization and increased free calcium in acetylcholine-stimulated endothelial cells. Am J Physiol. 1988;255:H965-H969.
    • (1988) Am J Physiol , vol.255
    • Busse, R.1    Fichtner, H.2    Luckhoff, A.3    Kohlhardt, M.4
  • 14
    • 0024253499 scopus 로고
    • Acetylcholine-induced calcium transients in primary cultures of rabbit aortic endothelial cells
    • Danthuluri NR, Cybulsky MI, Brock TA. Acetylcholine-induced calcium transients in primary cultures of rabbit aortic endothelial cells. Am J Physiol. 1988;255:H1549-H1553.
    • (1988) Am J Physiol , vol.255
    • Danthuluri, N.R.1    Cybulsky, M.I.2    Brock, T.A.3
  • 15
    • 0028092958 scopus 로고
    • Nitric oxide synthases: Roles, tolls, and controls
    • Nathan C, Xie Q-w. Nitric oxide synthases: roles, tolls, and controls. Cell. 1994;78:915-918.
    • (1994) Cell , vol.78 , pp. 915-918
    • Nathan, C.1    Xie, Q.-W.2
  • 16
    • 76549210297 scopus 로고
    • Measurement of changes in human limb volume by means of a mercury-in-rubber strain gauge
    • Whitney RJ. Measurement of changes in human limb volume by means of a mercury-in-rubber strain gauge. J Physiol (Lond). 1948;109:5P-6P.
    • (1948) J Physiol (Lond) , vol.109
    • Whitney, R.J.1
  • 17
    • 0001041456 scopus 로고
    • The effect of application of an arterial occlusion cuff to the wrist on the blood flow in the human forearm
    • Kerslake DM. The effect of application of an arterial occlusion cuff to the wrist on the blood flow in the human forearm. J Physiol (Lond). 1949;108: 451-457.
    • (1949) J Physiol (Lond) , vol.108 , pp. 451-457
    • Kerslake, D.M.1
  • 18
    • 0019195506 scopus 로고
    • The obligatory role of endothelial cells in the relaxation of arterial smooth muscle to acetylcholine
    • Furchgott RF, Zawadzki JV. The obligatory role of endothelial cells in the relaxation of arterial smooth muscle to acetylcholine. Nature. 1980;288: 373-376.
    • (1980) Nature , vol.288 , pp. 373-376
    • Furchgott, R.F.1    Zawadzki, J.V.2
  • 19
    • 0017795243 scopus 로고
    • Effects of sodium nitroprusside and other smooth muscle relaxant on cyclic-GMP formation in smooth muscle and platelets
    • Bohme E, Graf H, Schultz G. Effects of sodium nitroprusside and other smooth muscle relaxant on cyclic-GMP formation in smooth muscle and platelets. Adv Cyclic Nucl Res. 1978;9:131-143.
    • (1978) Adv Cyclic Nucl Res , vol.9 , pp. 131-143
    • Bohme, E.1    Graf, H.2    Schultz, G.3
  • 20
    • 0024428094 scopus 로고
    • Effects of endothelium-derived nitric oxide on peripheral arteriolar tone in man
    • Vallance P, Collier J, Moncada S. Effects of endothelium-derived nitric oxide on peripheral arteriolar tone in ma n. Lancet. 1989;2:997-1000.
    • (1989) Lancet , vol.2 , pp. 997-1000
    • Vallance, P.1    Collier, J.2    Moncada, S.3
  • 21
    • 0014528745 scopus 로고
    • Influence of initial resistance on the magnitude of response to vasomotor stimuli
    • Myers HA, Honig CR. Influence of initial resistance on the magnitude of response to vasomotor stimuli. Am J Physiol. 1969;216:1429-1436.
    • (1969) Am J Physiol , vol.216 , pp. 1429-1436
    • Myers, H.A.1    Honig, C.R.2
  • 22
    • 0027404913 scopus 로고
    • Intracellular cyclic GMP receptor proteins
    • Lincoln TM, Cornwall TL. Intracellular cyclic GMP receptor proteins. FASEB J. 1993;7:328-338.
    • (1993) FASEB J , vol.7 , pp. 328-338
    • Lincoln, T.M.1    Cornwall, T.L.2
  • 23
    • 0028793485 scopus 로고
    • Endothelial release of nitric oxide contributes to the vasodilator effect of adenosine in humans
    • Smits P, Williams SB, Lipson DE, Banitt P, Rongen GA, Creager MA. Endothelial release of nitric oxide contributes to the vasodilator effect of adenosine in humans. Circulation. 1995;92:2135-2141.
    • (1995) Circulation , vol.92 , pp. 2135-2141
    • Smits, P.1    Williams, S.B.2    Lipson, D.E.3    Banitt, P.4    Rongen, G.A.5    Creager, M.A.6
  • 24
    • 0027208248 scopus 로고
    • Muscarinic receptors: Characterization, coupling and function
    • Caulfield MP. Muscarinic receptors: characterization, coupling and function. Pharmacol Ther. 1993;58:319-379.
    • (1993) Pharmacol Ther , vol.58 , pp. 319-379
    • Caulfield, M.P.1
  • 26
    • 0028831997 scopus 로고
    • Calcium signaling
    • Clapham DE. Calcium signaling. Cell. 1995;80:259-268.
    • (1995) Cell , vol.80 , pp. 259-268
    • Clapham, D.E.1
  • 27
    • 0024453294 scopus 로고
    • Inositol phosphate and cell signaling
    • Berridge MJ, Irvine RF. Inositol phosphate and cell signaling. Nature. 1989;341:197-205.
    • (1989) Nature , vol.341 , pp. 197-205
    • Berridge, M.J.1    Irvine, R.F.2
  • 28
    • 0025261231 scopus 로고
    • Defective venous adrenoceptor response in borderline hypertensive subjects is corrected by a low sodium diet
    • Feldman RD. Defective venous adrenoceptor response in borderline hypertensive subjects is corrected by a low sodium diet. J Clin Invest, 1990;85:647-652.
    • (1990) J Clin Invest , vol.85 , pp. 647-652
    • Feldman, R.D.1
  • 29
    • 0029161586 scopus 로고
    • Forearm beta adrenergic receptor-mediated vasodilation is impaired, without alteration of forearm norepinephrine spillover, in borderline hypertension
    • Stein CM, Nelson R, Deegan R, He H, Wood M, Wood AJJ. Forearm beta adrenergic receptor-mediated vasodilation is impaired, without alteration of forearm norepinephrine spillover, in borderline hypertension. J Clin Invest. 1995;96:579-585.
    • (1995) J Clin Invest , vol.96 , pp. 579-585
    • Stein, C.M.1    Nelson, R.2    Deegan, R.3    He, H.4    Wood, M.5    Wood, A.J.J.6
  • 30
    • 0024318279 scopus 로고
    • Elevated sympathetic nerve activity in borderline hypertensive humans: Evidence from direct intraneural recordings
    • Anderson EA, Sinkey CA, Lawton WJ, Mark AL. Elevated sympathetic nerve activity in borderline hypertensive humans: evidence from direct intraneural recordings. Hypertension. 1989;14:177-183.
    • (1989) Hypertension , vol.14 , pp. 177-183
    • Anderson, E.A.1    Sinkey, C.A.2    Lawton, W.J.3    Mark, A.L.4
  • 31
    • 0030605375 scopus 로고    scopus 로고
    • Adrenergic receptors: Evolving concepts and clinical implications
    • Insel PA. Adrenergic receptors: evolving concepts and clinical implications. N Engl J Med. 1996;334:580-585.
    • (1996) N Engl J Med , vol.334 , pp. 580-585
    • Insel, P.A.1
  • 32
    • 0026536407 scopus 로고
    • Decreased endothelium-dependent hyperpolarization to acetylcholine in smooth muscle of mesenteric artery of spontaneously hypertensive rats
    • Fujii K, Tominaga M, Ohmori S, Kobayashi K, Koga T, Takata Y, Fumjishima M. Decreased endothelium-dependent hyperpolarization to acetylcholine in smooth muscle of mesenteric artery of spontaneously hypertensive rats. Circ Res. 1992;70:660-669.
    • (1992) Circ Res , vol.70 , pp. 660-669
    • Fujii, K.1    Tominaga, M.2    Ohmori, S.3    Kobayashi, K.4    Koga, T.5    Takata, Y.6    Fumjishima, M.7
  • 33
    • 0026504552 scopus 로고
    • Endothelium-dependent relaxation and hyperpolarization in aorta from control and renal hypertensive rats
    • Van de Voorde J, Vanheel B, Leusen I. Endothelium-dependent relaxation and hyperpolarization in aorta from control and renal hypertensive rats. Circ Res. 1992;70:1-8.
    • (1992) Circ Res , vol.70 , pp. 1-8
    • Van De Voorde, J.1    Vanheel, B.2    Leusen, I.3
  • 34
    • 0022545417 scopus 로고
    • Endothelium-dependent contractions to ace-tylcholine in the aorta of the spontaneously hypertensive rats
    • Lüscher TF, Vanhoutte PM. Endothelium-dependent contractions to ace-tylcholine in the aorta of the spontaneously hypertensive rats. Hypertension. 1986;8:344-348.
    • (1986) Hypertension , vol.8 , pp. 344-348
    • Lüscher, T.F.1    Vanhoutte, P.M.2
  • 35
    • 0023909563 scopus 로고
    • Endothelium-dependent and endothelium-independent vasodilation in resistance arteries from hypertensive rats
    • Tesfamariam B, Halpern W. Endothelium-dependent and endothelium-independent vasodilation in resistance arteries from hypertensive rats. Hypertension. 1988;11:440-444.
    • (1988) Hypertension , vol.11 , pp. 440-444
    • Tesfamariam, B.1    Halpern, W.2
  • 36
    • 0030641082 scopus 로고    scopus 로고
    • Cyclooxygenase inhibition restores nitric oxide activity in essential hypertension
    • Taddei S, Virdis A, Ghiadoni L, Magagna A, Salvetti A. Cyclooxygenase inhibition restores nitric oxide activity in essential hypertension. Hypertension. 1997;29(part 2):274-279.
    • (1997) Hypertension , vol.29 , Issue.PART 2 , pp. 274-279
    • Taddei, S.1    Virdis, A.2    Ghiadoni, L.3    Magagna, A.4    Salvetti, A.5


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