TNF-α enhances contraction and inhibits endothelial NO-cGMP relaxation in systemic vessels of pregnant rats

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 283, Issue 1 52-1, 2002, Pages

  Giardina, Jena B ^a   Green, Gachavis M ^a   Cockrell, Kathy L ^a   Granger, Joey P ^a   Khalil, Raouf A ^a,b  

^a UNIVERSITY OF MISSISSIPPI SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF MISSISSIPPI MEDICAL CENTER   (United States)

Author keywords

Arterial pressure; Cytokines; Endothelium; Nitric oxide; Pregnancy; Tumor necrosis factor

Indexed keywords

1H 1,2,4 OXADIAZOLO[4,3 A]QUINOXALIN 1 ONE; ACETYLCHOLINE; BRADYKININ; CYCLIC GMP; CYTOKINE; N(G) METHYLARGININE; NITRATE; NITRIC OXIDE; NITRIC OXIDE DONOR; NITRIC OXIDE SYNTHASE INHIBITOR; NITRITE; NITROPRUSSIDE SODIUM; PHENYLEPHRINE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL TISSUE; ARTERIAL PRESSURE; ARTICLE; BLOOD VESSEL REACTIVITY; CONTROLLED STUDY; FEMALE; HEMODYNAMICS; MATERNAL HYPERTENSION; NONHUMAN; PREECLAMPSIA; PREGNANCY; PRIORITY JOURNAL; RAT; VASCULAR ENDOTHELIUM; VASCULAR RESISTANCE; VASOCONSTRICTION; VASODILATATION;

EID: 0036334223     PISSN: 03636119     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpregu.00704.2001     Document Type: Article

References (72)

1. Enhanced endothelium-derived relaxing factor activity in pregnant, spontaneously hypertensive rats
2. Tumor necrosis factor-α-induced hypertension in pregnant rats results in decreased renal neuronal nitric oxide synthase expression
3. Reduced uterine perfusion pressure during pregnancy in the rat is associated with increases in arterial pressure and changes in renal nitric oxide
4. Differential expression of renal nitric oxide synthase isoforms during pregnancy in rats
5. Endothelial cytosolic proteins bind to the 3' untranslated region of endothelial nitric oxide synthase mRNA: Regulation by tumor necrosis factor-α
6. Potentiation by tumour necrosis factor-α of calcium signals induced by bradykinin and carbachol in human tracheal smooth muscle cells
7. Importance of nitric oxide in control of systemic and renal hemodynamics during normal pregnancy: Studies in the rat and implications for preeclampsia
8. Bradykinin-regulated interactions of the mitogen-activated protein kinase pathway with the endothelial nitric-oxide synthase
9. Plasma tumor necrosis factor-α levels and the -238*A promoter polymorphism in patients with antiphospholipid syndrome
10. An endothelium-derived hyperpolarizing factor distinct from NO and prostacyclin is a major endothelium-dependent vasodilator in resistance vessels of wild-type and endothelial NO synthase knockout mice
11. Animal models of pre-eclampsia: Do they exist?
12. Placental cytokines and the pathogenesis of preeclampsia
13. Identification of increased nitric oxide biosynthesis during pregnancy in rats
14. Circulating levels of immunoreactive cytokines in women with preeclampsia
15. Plasma levels, urinary excretion, and metabolic production of cGMP during gestation in rats
16. Decreased endothelium-dependent vascular relaxation during reduction of uterine perfusion pressure in pregnant rat
17. 2+ entry into vascular smooth muscle during NO synthesis inhibition in pregnant rats
18. Endogenous modulation of the blunted adrenergic response in resistance-sized mesenteric arteries from the pregnant rat
19. Decreased endothelium-dependent vascular relaxation via the NO-cGMP pathway during TNF-α-induced hypertension in pregnant rats
20. Renal hemodynamics and volume homeostasis in pregnancy
21. A role for brain angiotensin II in experimental pregnancy-induced hypertension in laboratory rats
22. Levels of dimethylarginines and cytokines in mild and severe preeclampsia
23. Tumor necrosis factor-α activates pulmonary artery endothelial protein kinase C
24. Preeclampsia and related disorders. Clinical aspects and relevance of endothelin and nitric oxide
25. The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine
26. Role of endothelin B receptors in enhancing endothelium-dependent nitric oxide-mediated vascular relaxation during high salt diet
27. Long-term elevation of plasma TNF-α increases arterial pressure and reduces kidney function in pregnant rats
28. Tumor necrosis factor-α inhibits endothelium-dependent relaxation
29. Increased concentrations of cytokines interleukin-6 and interleukin-1 receptor antagonist in plasma of women with pre-eclampsia: A mechanism for endothelial dysfunction?
30. Relationship between cyclic guanosine 3',5'-monophosphate formation and relaxation of coronary arterial smooth muscle by glyceryl trinitrate, nitroprusside, nitrite and nitric oxide: Effects of methylene blue and methemoglobin
31. Tumour necrosis factor-α enhances bradykinin-induced signal transduction via activation of Ras/Raf/MEK/MAPK in canine tracheal smooth muscle cells
32. The soluble guanylyl cyclase inhibitor 1H-[1,2,4]oxadiazolo[4,3- α]quinoxalin-1-one (ODQ) inhibits relaxation of rabbit aortic rings induced by carbon monoxide, nitric oxide, and glyceryl trinitrate
33. Biological actions and properties of endothelium-derived nitric oxide formed and released from artery and vein
34. The pharmacological and physiological role of cyclic GMP in vascular smooth muscle relaxation
35. Enhanced vascular reactivity during inhibition of nitric oxide synthesis in pregnant rats
36. TNF-α inhibits flow and insulin signaling leading to NO production in aortic endothelial cells
37. Endothelin 1 mediates ex vivo coronary vasoconstriction caused by exogenous and endogenous cytokines
38. Tumor necrosis factor-α is decreased in the umbilical cord plasma of patients with severe preeclampsia
39. Tumor necrosis factor-α is elevated in plasma and amniotic fluid of patients with severe preeclampsia
40. Renal physiology and disease in pregnancy
41. Increased peripheral resistance during reduced uterine perfusion pressure hypertension in pregnant rabbits
42. Transcriptional regulation of the endothelin-1 gene by TNF-α
43. Endothelial cell activation by tumour necrosis factor-α (TNF-α) and the development of pre-eclampsia
44. Targeting and translocation of endothelial nitric oxide synthase
45. Coordinated control of endothelial nitric-oxide synthase phosphorylation by protein kinase C and the cAMP-dependent protein kinase
46. ω-nitro-L-arginine, an inhibitor of nitric oxide synthesis, increases blood pressure in rats and reverses the pregnancy-induced refractoriness to vasopressor agents
47. Prolonged blockade of nitric oxide synthesis in gravid rats produces sustained hypertension, preteinuria, thrombocytopenia, and intrauterine growth retardation
48. The discovery of nitric oxide as the endogenous nitrovasodilator
49. Nitric oxide, the endothelium, pregnancy and pre-eclampsia
50. Inhibition of nitric oxide synthase activity in dispersed gastric muscle cells by protein kinase C
51. The role of nitric oxide in the altered vascular reactivity of pregnancy in the rat
52. Selective guanylyl cyclase inhibitor reverses nitric oxide-induced vasorelaxation
53. Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor
54. Role of the endothelium in adrenergic responses of mesenteric artery rings of pregnant rats
55. Tumour necrosis factor-α activates a calcium sensitization pathway in guinea-pig bronchial smooth muscle
56. Differential effect of MLC kinase in TNF-α-induced endothelial cell apoptosis and barrier dysfunction
57. A chimeric transmembrane domain directs endothelial nitric-oxide synthase palmitoylation and targeting to plasmalemmal caveolae
58. Characterization of three inhibitors of endothelial nitric oxide synthase in vitro and in vivo
59. 2+] determines myosin phosphorylation in agonist-stimulated swine arterial smooth muscle
60. Tumor necrosis factor-α-238 and - 308 polymorphisms do not associate with insulin resistance in hypertensive subjects
61. Evidence for the presence of an unusual nitric oxide- and citrulline-producing enzyme in rat kidney
62. Nitric oxide and pregnancy
63. Women with preeclampsia have higher plasma endothelin levels than women with normal pregnancies
64. Differential sensitivity among nitric oxide donors toward ODQ-mediated inhibition of vascular relaxation
65. Vascular biology. Old-timer makes a comeback
66. Interleukin-6, tumour necrosis factor and soluble tumour necrosis factor receptors in women with pre-eclampsia
67. Administration of tumor necrosis factor-α in vivo depresses endothelium-dependent relaxation
68. Induction of calcium-dependent nitric oxide synthases by sex hormones
69. Nitric oxide-mediated vasodilation in human pregnancy
70. Plasma tumor necrosis factor-α soluble receptor p55 (sTNFp55) concentrations in eclamptic, preeclamptic, and normotensive pregnant Zimbabwean women
71. Tumor necrosis factor inhibits stimulated but not basal release of nitric oxide
72. Tumor necrosis factor downregulates an endothelial nitric oxide synthase mRNA by shortening its half-life