Phosphorylation of caldesmon by ERK MAP kinases in smooth muscle

American Journal of Physiology - Cell Physiology

Volumn 278, Issue 4 47-4, 2000, Pages

  Hedges, Jason C ^a   Oxhorn, Brian C ^a   Carty, Michael ^a   Adam, Leonard P ^b   Yamboliev, Ilia A ^a   Gerthoffer, William T ^a  

^a UNIVERSITY OF NEVADA   (United States)

^b BRISTOL MYERS SQUIBB   (United States)

Author keywords

Carbachol; Extracellular signal regulated kinase; p38 mitogen activated protein kinase; PD 98059; SB 203580; Trachea

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ACETYLCHOLINE; CALDESMON; CARBACHOL; MITOGEN ACTIVATED PROTEIN KINASE; OTENZEPAD; PLATELET DERIVED GROWTH FACTOR;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; FEMALE; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; TRACHEA MUSCLE;

ANIMALIA;

EID: 0034129032     PISSN: 03636143     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpcell.2000.278.4.c718     Document Type: Article

References (27)

1. Adam LP, Haeberle JR, and Hathaway DR. Phosphorylation of caldesmon in arterial smooth muscle. J Biol Chem 264: 7698-7703, 1989.
2. Adam LP, Franklin MT, Raff GJ, and Hathaway DR. Activation of mitogen-activated protein kinase in porcine carotid arteries. Circ Res 76: 183-190, 1995.
3. Adam LP, Gapinski CJ, and Hathaway DR. Phosphorylation sequences in h-caldesmon from phorbol ester-stimulated canine aortas. FEBS Lett 302: 223-226, 1992.
4. Childs TJ, Watson MH, Sanghera JS, Campbell DL, Pelech SL, and Mak AS. Phosphorylation of smooth muscle caldesmon by mitogen-activated protein (MAP) kinase and expression of MAP kinase in differentiated smooth muscle cells. J Biol Chem 267: 22853-22859, 1992.
5. Eglen RM, Hegde SS, and Watson N. Muscarinic receptor subtypes and smooth muscle function. Pharmacol Rev 48: 531-565, 1996.
6. Ehlert FJ. The interaction of 4-DAMP mustard with subtypes of the muscarinic receptor. Life Sci 58: 1971-1978. 1996.
7. Ehlert FJ and Griffin MT. The use of irreversible ligands to inactivate receptor subtypes: 4-DAMP mustard and muscarinic receptors in smooth muscle. Life Sci 62: 1659-1664, 1998.
8. Franklin MT, Wang CL, and Adam LP. Stretch-dependent activation and desensitization of mitogen-activated protein kinase in carotid arteries. Am J Physiol Cell Physiol 273: C1819-C1827, 1997.
9. Gerthoffer WT, Yamboliev IA, Pohl J, Haynes R, Dang S, and McHugh J. Activation of MAP kinases in airway smooth muscle. Am J Physiol Lung Cell Mol Physiol 272: L244-L252, 1997.
10. Gerthoffer WT, Yamboliev IA, Shearer M, Pohl J, Haynes R, Dang S, Sato K, and Sellers JR. Activation of MAP kinases and phosphorylation of caldesmon in canine colonic smooth muscle. J Physiol (Lond) 495: 597-609, 1996.
11. Gorenne I, Su X, and Moreland RS. Inhibition of p42 and p44 MAP kinase does not alter smooth muscle contraction in swine carotid artery. Am J Physiol Heart Circ Physiol 275: H131-H138, 1998.
12. Haeberle JR, Trybus KM, Hemric ME, and Warshaw DM. The effects of smooth muscle caldesmon on actin filament motility. J Biol Chem 267: 23001-23006, 1992.
13. Halayko AJ, Camoretti-Mercado B, Forsythe SM, Vieira JE, Mitchell RW, Wylam ME, Hershenson MB, and Solway J. Divergent differentiation paths in airway smooth muscle culture: induction of functionally contractile myocytes. Am J Physiol Lung Cell Mol Physiol 276: L197-L206, 1999.
14. Hedges JC, Yamboliev IA, and Gerthoffer WT. p38 MAP kinase expression and activation in smooth muscle. Am J Physiol Cell Physiol 275: C527-C534, 1998.
15. Hirshman CA, Lande B, and Croxton TL. Role of M2 muscarinic receptors in airway smooth muscle contraction. Life Sci 64: 443-448, 1999.
16. Horiuchi KY and Chacko S. Effect of unphosphorylated smooth muscle myosin on caldesmon-mediated regulation of actin filament velocity. J Muscle Res Cell Motil 16: 11-19, 1995.
17. Humphrey MB, Herrera-Sosa H, Gonzalez G, Lee R, and Bryan J. Cloning of cDNAs encoding human caldesmons. Gene 112: 197-204, 1992.
18. Katoch SS and Moreland RS. Agonist and membrane depolarization-induced activation of MAP kinase in the swine carotid artery. Am J Physiol Heart Circ Physiol 269: H222-H229, 1995.
19. Larsen JK, Yamboliev IA, Weber LA, and Gerthoffer WT. Phosphorylation of the 27 kDa heat shock protein via p38 MAP kinase and MAPKAP kinase in smooth muscle. Am J Physiol Lung Cell Mol Physiol 273: L930-L940, 1997.
20. Marston SB, Redwood CS, and Lehman W. Reversal of caldesmon function by anti-caldesmon antibodies confirms its role in the calcium regulation of vascular smooth muscle thin filaments. Biochem Biophys Res Commun 155: 197-202, 1988.
21. 2+ sensitivity in rabbit smooth muscle. J Physiol (Lond) 487: 283-289, 1995.
22. Pinter K and Marston SB. Phosphorylation of vascular smooth muscle caldesmon by endogenous kinase. FEBS Lett 305: 192-196, 1992.
23. Qian NX, Russell M, and Johnson GL. ACh muscarinic receptor regulation of the Ras/Raf/MAP kinase pathway. Life Sci 56: 945-949, 1995.
24. Redwood CS, Marston SB, and Gusev NB. The functional effects of mutations Thr673→Asp and Ser702→Asp at the Prodirected kinase phosphorylation sites in the C-terminus of chicken gizzard caldesmon. FEBS Lett 327: 85-89, 1993.
25. Sutherland C and Walsh MP. Phosphorylation of caldesmon prevents its interaction with smooth muscle myosin. J Biol Chem 264: 578-583, 1989.
26. r caldesmon by protein kinase C modulates the regulatory function of this protein on the interaction between actin and myosin. Eur J Biochem 188: 495-500, 1990.
27. Wan Y, Kurosaki T, and Huang XY. Tyrosine kinases in activation of the MAP kinase cascade by G-protein-coupled receptors. Nature 380: 541-544, 1996.