Ca2+-insensitive vascular protein kinase C during pregnancy and NOS inhibition

Hypertension

Volumn 34, Issue 4 II, 1999, Pages 924-930

  Kanashiro, Celia A ^a   Alexander, Barbara T ^a   Granger, Joey P ^a   Khalil, Raouf A ^a  

^a UNIVERSITY OF MISSISSIPPI SCHOOL OF MEDICINE   (United States)

Author keywords

Hypertension, pregnancy; Muscle, smooth, vascular; Nitric oxide; Preeclampsia

Indexed keywords

ARGININE; CALCIUM; CALPHOSTIN C; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PHENYLEPHRINE; PHORBOL DIBUTYRATE; PROTEIN KINASE C; STAUROSPORINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME INHIBITION; ENZYME LOCALIZATION; FEMALE; MATERNAL HYPERTENSION; MUSCLE ISOMETRIC CONTRACTION; NONHUMAN; PATHOGENESIS; PREECLAMPSIA; PREGNANCY; PRIORITY JOURNAL; RAT; VASCULAR SMOOTH MUSCLE;

EID: 0032753834     PISSN: 0194911X     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.hyp.34.4.924     Document Type: Article

References (31)

1. Davison JM, Dunlop W. Renal hemodynamics and tubular function in normal human pregnancy. Kidney Int. 1980;18:152-161.
2. Dowell RT, Kauer CD. Uteroplacental blood flow at rest and during exercise in late gestation conscious rats. J Appl Physiol. 1993;74: 2079-2085.
3. Gant NF, Daley GL, Chand S, Whalley PJ, MacDonald PC. A study of angiotensin II pressor response throughout primigravid pregnancy. J Clin Invest. 1973;52:2682-2689.
4. Davidge ST, McLaughlin MK. Endogenous modulation of the blunted adrenergic response in resistance-sized mesenteric arteries from the pregnant rat. Am J Obstet Gynecol. 1992;167:1691-1698.
5. Sladek SM, Magness RR, Conrad KP. Nitric oxide and pregnancy. Am J Physiol. 1997;272:R441-R463.
6. Conrad KP, Vernier KA. Plasma levels, urinary excretion and metabolic production of cGMP during gestation in rats. Am J Physiol. 1989;257: R847-R853.
7. National High Blood Pressure Education Program Working Group. Report on high blood pressure in pregnancy: consensus report. Am J Obstet Gynecol. 1990;163:1689-1712.
8. Lindheimer MD, Katz AI. Hypertension in pregnancy. N Engl J Med. 1985;313:675-680.
9. Friedman SA, Lubarsky SL, Ahokas RA, Nova A, Sibai BM. Preeclampsia and related disorders: clinical aspects and relevance of endothelin and nitric oxide. Clin Perinatol. 1995;2;343-355.
10. Baylis C, Suto T, Conrad K. Importance of nitric oxide in control of systemic and renal hemodynamics during normal pregnancy: studies in the rat and implications for preeclampsia. Hypertens Pregnancy. 1996; 15:147-169.
11. Molnar M, Suto T, Toth T, Hertelendy F. Prolonged blockade of nitric oxide synthesis in gravid rats produces sustained hypertension, proteinuria, thrombocytopenia, and intrauterine growth retardation. Am J Obstet Gynecol. 1994;170:1458-1466.
12. Novak J, Cockrell K, Kassab S, Reckelhoff, Granger JP. Chronic nitric oxide synthesis inhibition during pregnancy increases thromboxane excretion in rats. FASEB J. 1997;11:A78. Abstract.
13. Khalil RA, Crews JK, Novak J, Kassab S, Granger JP. Enhanced vascular reactivity during inhibition of nitric oxide synthesis in pregnant rats. Hypertension. 1998;31:1065-1069.
14. 2+ entry into vascular smooth muscle during NO synthesis inhibition in pregnant rats. Am J Physiol. 1999;276:R530-R538.
15. Nishizuka Y. Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C. Science. 1992;258:607-614.
16. Kanashiro CA, Khalil RA. Signal transduction by protein kinase C in mammalian cells. Clin Exp Pharmacol Physiol. 1998;25:974-985.
17. Khalil RA, van Breemen C. Sustained contraction of vascular smooth muscle: calcium influx or C-kinase activation? J Pharmacol Exp Ther. 1988;244:537-542.
18. Jiang MJ, Morgan KG. Intracellular calcium levels in phorbol esterinduced contractions of vascular smooth muscle. Am J Physiol. 1987; 253:H1365-H1371.
19. Liou YM, Morgan KG. Redistribution of protein kinase C isoforms in association with vascular hypertrophy of rat aorta. Am J Physiol. 1994; 267:C980-C989.
20. 2+-independent isoforms of protein kinase C differentially translocate in smooth muscle. Am J Physiol. 1992;263:C714-C719.
21. G-Nitro L-arginine, an inhibitor of nitric oxide synthesis, increases blood pressure in rats and reverses the pregnancy induced refractoriness to vasopressor agents. Am J Obstet Gynecol. 1992; 166:1560-1567.
22. 2+ entry during coronary artery contraction by vasoactive eicosanoids. Can J Physiol Pharmacol. 1999;7:112-122.
23. Gopalakrishna R, Chen ZH, Gundimeda U. Nitric oxide and nitric oxide-generating agents induce a reversible inactivation of protein kinase C activity and phorbol ester binding. J Biol Chem. 1993;268:27180-27185.
24. Nishizawa S, Yamamoto S, Yokoyama T, Uemura K. Dysfunction of nitric oxide induces protein kinase C activation resulting in vasospasm after subarachnoid hemorrhage. Neurol Res. 1997;19:558-562.
25. Studer RK, DeRubertis FR, Craven PA. Nitric oxide suppresses increases in mesangial cell protein kinase C, transforming growth factor beta, and fibronectin synthesis induced by thromboxane. J Am Soc Nephrol. 1996; 7:999-1005.
26. Lang D, Lewis MJ. Endothelium-derived relaxing factor inhibits the endothelin-1-induced increase in protein kinase C activity in rat aorta. Br J Pharmacol. 1991;104:139-144.
27. Sauro MD, Fitzpatrick DF. Atrial natriuretic peptides inhibit protein kinase C activation in rat aortic smooth muscle. Pept Res. 1990;3: 138-141.
28. Barnett RL, Ruffini L, Ramsammy L, Pasmantier R, Friedlaender MM, Nord EP. cGMP antagonizes angiotensin-mediated phophatidylcholine hydrolysis and C kinase activation in mesangial cells. Am J Physiol. 1995;268:C376-C381.
29. Alexander BT, Miller MT, Kassab S, Novak J, Reckelhoff JF, Kruckeberg WC, Granger JP. Differential expression of renal nitric oxide synthase isoforms during pregnancy in rats. Hypertension. 1999;33: 435-439.
30. Baylis C, Engels K. Adverse interactions between pregnancy and a new model of systemic hypertension produced by chronic blockade of endothelial derived relaxing factor (EDRF) in the rat. Clin Exp Hypertens. 1992;B11:117-129.
31. Edwards DL, Arora CP, Bui DT, Castro LC. Long-term nitric oxide blockade in the pregnant rat: effects on blood pressure and plasma levels of endothelin-1. Am J Obstet Gynecol. 1996;175:484-488.