Oxidative stress causes renal dopamine D1 receptor dysfunction and hypertension via mechanisms that involve nuclear factor-κB and protein kinase C

Journal of the American Society of Nephrology

Volumn 18, Issue 5, 2007, Pages 1446-1457

  Banday, Anees Ahmad ^a   Fazili, Fatima Rizwan ^a   Lokhandwala, Mustafa F ^a  

^a UNIVERSITY OF HOUSTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2,3,4,5 TETRAHYDRO 7,8 DIHYDROXY 1 PHENYL 1H 3 BENZAZEPINE; 8 CHLORO 2,3,4,5 TETRAHYDRO 3 METHYL 5 PHENYL 1H 3 BENZAZEPIN 7 OL HYDROGEN MALEATE; BUTHIONINE SULFOXIMINE; DOPAMINE 1 RECEPTOR; G PROTEIN COUPLED RECEPTOR KINASE 2; GUANINE NUCLEOTIDE BINDING PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; OXIDIZING AGENT; PROTEIN KINASE C; TAP WATER; TEMPOL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; DIURETIC ACTIVITY; DRUG MECHANISM; ENZYME ACTIVITY; GENE TRANSLOCATION; HYPERTENSION; KIDNEY DISEASE; MALE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN DEFECT; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; RAT;

EID: 34248209629     PISSN: 10466673     EISSN: None     Source Type: Journal    
DOI: 10.1681/ASN.2006121373     Document Type: Article

References (50)

1. Zeng C, Felder RA, Jose PA: A new approach for treatment of hypertension: Modifying D1 dopamine receptor function. Cardiovasc Hematol Agents Med Chem 4: 369-377, 2006
2. Missale C, Nash SR, Robinson SW, Jaber M, Caron MG: Dopamine receptors: From structure to function. Physiol Rev 78: 189-225, 1998
3. Aperia AC: Intrarenal dopamine: A key signal in the interactive regulation of sodium metabolism. Annu Rev Physiol 62: 621-647, 2000
4. Zeng C, Eisner GM, Felder RA, Jose PA: Dopamine receptor and hypertension. Curr Med Chem Cardiovasc Hematol Agents 3: 69-77, 2005
5. Bek MJ, Eisner GM, Felder RA, Jose PA: Dopamine receptors in hypertension. Mt Sinai J Med 68: 362-369, 2001
6. Jose PA, Eisner GM, Felder RA: Renal dopamine receptors in health and hypertension. Pharmacol Ther 80: 149-182, 1998
7. Banday AA, Marwaha A, Tallam LS, Lokhandwala MF: Tempol reduces oxidative stress, improves insulin sensitivity, decreases renal dopamine D1 receptor hyperphosphorylation, and restores D1 receptor-G-protein coupling and function in obese Zucker rats. Diabetes 54: 2219-2226, 2005
8. Nishi A, Eklof AC, Bertorello AM, Aperia A: Dopamine regulation of renal Na+, K(+)-ATPase activity is lacking in Dahl salt-sensitive rats. Hypertension 21: 767-771, 1993
9. Ohbu K, Kaskel FJ, Kinoshita S, Felder RA: Dopamine-1 receptors in the proximal convoluted tubule of Dahl rats: Defective coupling to adenylate cyclase. Am J Physiol 268: R231-R235, 1995
10. Sela S, White BH, Uh M, Kimura K, Patel S, Sidhu A: Dysfunctional D1A receptor-G-protein coupling in proximal tubules of spontaneously hypertensive rats is not due to abnormal G-proteins. J Hypertens 15: 259-267, 1997
11. Manning RD Jr, Meng S, Tian N: Renal and vascular oxidative stress and salt-sensitivity of arterial pressure. Acta Physiol Scand 179: 243-250, 2003
12. Welch WJ, Mendonca M, Blau J, Karber A, Dennehy K, Patel K, Lao YS, Jose PA, Wilcox CS: Antihypertensive response to prolonged tempol in the spontaneously hypertensive rat. Kidney Int 68: 179-187, 2005
13. White BH, Sidhu A: Increased oxidative stress in renal proximal tubules of the spontaneously hypertensive rat: A mechanism for defective dopamine D1A receptor/G-protein coupling. J Hypertens 16: 1659-1665, 1998
14. Yang Z, Asico LD, Yu P, Wang Z, Jones JE, Escano CS, Wang X, Quinn MT, Sibley DR, Romero GG, Felder RA, Jose PA: D5 dopamine receptor regulation of reactive oxygen species production, NADPH oxidase, and blood pressure. Am J Physiol Regul Integr Comp Physiol 290: R96-R104, 2006
15. Fardoun RZ, Asghar M, Lokhandwala M: Role of oxidative stress in defective renal dopamine D1 receptor-G protein coupling and function in old Fischer 344 rats. Am J Physiol Renal Physiol 291: F945-F951, 2006
16. Marwaha A, Banday AA, Lokhandwala MF: Reduced renal dopamine D1 receptor function in streptozotocin-induced diabetic rats. Am J Physiol Renal Physiol 286: F451-F457, 2004
17. Ferguson SS: Evolving concepts in G protein-coupled receptor endocytosis: The role in receptor desensitization and signaling. Pharmacol Rev 53: 1-24, 2001
18. Diviani D, Lattion AL, Cotecchia S: Characterization of the phosphorylation sites involved in G protein-coupled receptor kinase- and protein kinase C-mediated desensitization of the alpha1B-adrenergic receptor. J Biol Chem 272: 28712-28719, 1997
19. Reiter E, Lefkowitz RJ: GRKs and beta-arrestins: Roles in receptor silencing, trafficking and signaling. Trends Endocrinol Metab 17: 159-165, 2006
20. Asghar M, Banday AA, Fardoun RZ, Lokhandwala MF: Hydrogen peroxide causes uncoupling of dopamine D1-like receptors from G proteins via a mechanism involving protein kinase C and G-protein-coupled receptor kinase 2. Free Radic Biol Med 40: 13-20, 2006
21. Karin M, Lin A: NF-kappaB at the crossroads of life and death. Nat Immunol 3: 221-227, 2002
22. Baldwin AS Jr: The NF-kappa B and I kappa B proteins: New discoveries and insights. Annu Rev Immunol 14: 649-683, 1996
23. Surh YJ, Kundu JK, Na HK, Lee JS: Redox-sensitive transcription factors as prime targets for chemoprevention with anti-inflammatory and antioxidative phytochemicals. J Nutr 135: 2993S-3001S, 2005
24. Liu J, Yang D, Minemoto Y, Leitges M, Rosner MR, Lin A: NF-kappaB is required for UV-induced JNK activation via induction of PKCdelta. Mol Cell 21: 467-480, 2006
25. Mihara M, Uchiyama M: Determination of malonaldehyde precursor in tissues by thiobarbituric acid test. Anal Biochem 86: 271-278, 1978
26. Kansra V, Hussain T, Lokhandwala MF: Alterations in dopamine DA1 receptor and G proteins in renal proximal tubules of old rats. Am J Physiol 273: F53-F59, 1997
27. Wang HY, Undie AS, Friedman E: Evidence for the coupling of Gq protein to D1-like dopamine sites in rat striatum: Possible role in dopamine-mediated inositol phosphate formation. Mol Pharmacol 48: 988-994, 1995
28. Friedman E, Butkerait P, Wang HY: Analysis of receptor-stimulated and basal guanine nucleotide binding to membrane G proteins by sodium dodecyl sulfate-polyacrylamide gel electrophoresis. Anal Biochem 214: 171-178, 1993
29. Albrecht FE, Xu J, Moe OW, Hopfer U, Simonds WF, Orlowski J, Jose PA: Regulation of NHE3 activity by G protein subunits in renal brush-border membranes. Am J Physiol Regul Integr Comp Physiol 278: R1064-R1073, 2000
30. Asghar M, Hussain T, Lokhandwala MF: Overexpression of PKC-betaI and -delta contributes to higher PKC activity in the proximal tubules of old Fischer 344 rats. Am J Physiol Renal Physiol 285: F1100-F1107, 2003
31. Sanada H, Jose PA, Hazen-Martin D, Yu PY, Xu J, Bruns DE, Phipps J, Carey RM, Felder RA: Dopamine-1 receptor coupling defect in renal proximal tubule cells in hypertension. Hypertension 33: 1036-1042, 1999
32. Salomon Y, Londos C, Rodbell M: A highly sensitive adenylate cyclase assay. Anal Biochem 58: 541-548, 1974
33. Vaziri ND, Wang XQ, Oveisi F, Rad B: Induction of oxidative stress by glutathione depletion causes severe hypertension in normal rats. Hypertension 36: 142-146, 2000
34. Buczynski A, Wachowicz B, Kedziora-Kornatowska K, Tkaczewski W, Kedziora J: Changes in antioxidant enzymes activities, aggregability and malonyldialdehyde concentration in blood platelets from patients with coronary heart disease. Atherosclerosis 100: 223-228, 1993
35. Lacy F, O'Connor DT, Schmid-Schonbein GW: Plasma hydrogen peroxide production in hypertensives and normotensive subjects at genetic risk of hypertension. J Hypertens 16: 291-303, 1998
36. Prabha PS, Das UN, Koratkar R, Sagar PS, Ramesh G: Free radical generation, lipid peroxidation and essential fatty acids in uncontrolled essential hypertension. Prostaglandins Leukot Essent Fatty Acids 41: 27-33, 1990
37. Russo C, Olivieri O, Girelli D, Faccini G, Zenari ML, Lombardi S, Corrocher R: Anti-oxidant status and lipid peroxidation in patients with essential hypertension. J Hypertens 16: 1267-1271, 1998
38. Kumar KV, Das UN: Are free radicals involved in the pathobiology of human essential hypertension? Free Radic Res Commun 19: 59-66, 1993
39. Tsuchida H, Imai G, Shima Y, Satoh T, Owada S: Mechanism of sodium load-induced hypertension in non-insulin dependent diabetes mellitus model rats: Defective dopaminergic system to inhibit Na-K-ATPase activity in renal epithelial cells. Hypertens Res 24: 127-135, 2001
40. Umrani DN, Banday AA, Hussain T, Lokhandwala MF: Rosiglitazone treatment restores renal dopamine receptor function in obese Zucker rats. Hypertension 40: 880-885, 2002
41. Vaziri ND, Ding Y, Ni Z, Gonick HC: Altered nitric oxide metabolism and increased oxygen free radical activity in lead-induced hypertension: Effect of lazaroid therapy. Kidney Int 52: 1042-1046, 1997
42. Takahashi K, Nammour TM, Fukunaga M, Ebert J, Morrow JD, Roberts LJ 2nd, Hoover RL, Badr KF: Glomerular actions of a free radical-generated novel prostaglandin, 8-epiprostaglandin F2 alpha, in the rat. Evidence for interaction with thromboxane A2 receptors. J Clin Invest 90: 136-141, 1992
43. Tesfamariam B, Cohen RA: Role of superoxide anion and endothelium in vasoconstrictor action of prostaglandin endoperoxide. Am J Physiol 262: H1915-H1919, 1992
44. Atzori L, Olafsdottir K, Corriga AM, Bannenberg G, Ryrfeldt A, Moldeus P: Thiol modification in H202- and thromboxane-induced vaso- and bronchoconstriction in rat perfused lung. J Appl Physiol 71: 1309-1314, 1991
45. Gros R, Benovic JL, Tan CM, Feldman RD: G-protein-coupled receptor kinase activity is increased in hypertension. J Clin Invest 99: 2087-2093, 1997
46. Gros R, Chorazyczewski J, Meek MD, Benovic JL, Ferguson SS, Feldman RD: G-Protein-coupled receptor kinase activity in hypertension: Increased vascular and lymphocyte G-protein receptor kinase-2 protein expression. Hypertension 35: 38-42, 2000
47. Watanabe H, Xu J, Bengra C, Jose PA, Felder RA: Desensitization of human renal D1 dopamine receptors by G protein-coupled receptor kinase 4. Kidney Int 62: 790-798, 2002
48. Chuang TT, LeVine H 3rd, De Blasi A: Phosphorylation and activation of beta-adrenergic receptor kinase by protein kinase C. J Biol Chem 270: 18660-18665, 1995
49. Winstel R, Freund S, Krasel C, Hoppe E, Lohse MJ: Protein kinase cross-talk: Membrane targeting of the beta-adrenergic receptor kinase by protein kinase C. Proc Natl Acad Sci U S A 93: 2105-2109, 1996
50. Konishi H, Yamauchi E, Taniguchi H, Yamamoto T, Matsuzaki H, Takemura Y, Ohmae K, Kikkawa U, Nishizuka Y: Phosphorylation sites of protein kinase C delta in H2O2-treated cells and its activation by tyrosine kinase in vitro. Proc Natl Acad Sci U S A 98: 6587-6592, 2001