-
1
-
-
58749095825
-
Importance of mitochondrial dysfunction and oxidizing injuries in molecular pathology of Parkinson's disease
-
1:STN:280:DC%2BD1cjit1Gjuw%3D%3D
-
MI Shadrina PA Slominskii 2008 Importance of mitochondrial dysfunction and oxidizing injuries in molecular pathology of Parkinson's disease Mol. Biol. 42 809 819 1:STN:280:DC%2BD1cjit1Gjuw%3D%3D
-
(2008)
Mol. Biol.
, vol.42
, pp. 809-819
-
-
Shadrina, M.I.1
Slominskii, P.A.2
-
2
-
-
44949213717
-
Mitochondrial DNA damage and repair in neurodegenerative disorders
-
18463003 1:CAS:528:DC%2BD1cXnt1aktro%3D
-
J-L Yang L Weissman V Bohr MP Mattson 2008 Mitochondrial DNA damage and repair in neurodegenerative disorders DNA Repair 7 1110 1120 18463003 1:CAS:528:DC%2BD1cXnt1aktro%3D
-
(2008)
DNA Repair
, vol.7
, pp. 1110-1120
-
-
Yang, J.-L.1
Weissman, L.2
Bohr, V.3
Mattson, M.P.4
-
3
-
-
84875368844
-
Primary and secondary mitochondrial insufficiency in neurology and approaches for its correction
-
SN Illarioshkin 2007 Primary and secondary mitochondrial insufficiency in neurology and approaches for its correction Cons. Med. 9 105 106
-
(2007)
Cons. Med.
, vol.9
, pp. 105-106
-
-
Illarioshkin, S.N.1
-
4
-
-
57649210194
-
Impairing the mitochondrial fission and fusion balance: A new mechanism of neurodegeneration
-
19076450 1:CAS:528:DC%2BD1MXhsVaqu74%3D
-
AB Knott E Bossy-Wetzel 2008 Impairing the mitochondrial fission and fusion balance: a new mechanism of neurodegeneration Ann. N.Y. Acad. Sci. 1147 283 292 19076450 1:CAS:528:DC%2BD1MXhsVaqu74%3D
-
(2008)
Ann. N.Y. Acad. Sci.
, vol.1147
, pp. 283-292
-
-
Knott, A.B.1
Bossy-Wetzel, E.2
-
5
-
-
71849088759
-
Mitochondria: A therapeutic target in neurodegeneration
-
19853657 1:CAS:528:DC%2BD1MXhsFanurnJ
-
PI Moreira X Zhu X Wang, et al. 2010 Mitochondria: A therapeutic target in neurodegeneration Biochim. Biophys. Acta 1802 212 220 19853657 1:CAS:528:DC%2BD1MXhsFanurnJ
-
(2010)
Biochim. Biophys. Acta
, vol.1802
, pp. 212-220
-
-
Moreira, P.I.1
Zhu, X.2
Wang, X.3
-
6
-
-
81455157378
-
Mitochondrial dysfunction - The beginning of the end in Alzheimer's disease? Separate and synergistic models of tau and amyloid-β toxicity
-
1:CAS:528:DC%2BC3MXmtFWhtbY%3D
-
A Eckert K Schmidtt J Gotz 2011 Mitochondrial dysfunction - the beginning of the end in Alzheimer's disease? Separate and synergistic models of tau and amyloid-β toxicity Alzheimer's Res. Ther. 3 15 1:CAS:528: DC%2BC3MXmtFWhtbY%3D
-
(2011)
Alzheimer's Res. Ther.
, vol.3
, pp. 15
-
-
Eckert, A.1
Schmidtt, K.2
Gotz, J.3
-
7
-
-
77951737783
-
Mitochondrial fusion is required for mtDNA stability in skeletal muscle and tolerance of mtDNA mutation
-
20403324 1:CAS:528:DC%2BC3cXmtVWnsLg%3D
-
H Chen M Vermulst YE Wang, et al. 2010 Mitochondrial fusion is required for mtDNA stability in skeletal muscle and tolerance of mtDNA mutation Cell 141 280 289 20403324 1:CAS:528:DC%2BC3cXmtVWnsLg%3D
-
(2010)
Cell
, vol.141
, pp. 280-289
-
-
Chen, H.1
Vermulst, M.2
Wang, Y.E.3
-
8
-
-
0034938453
-
Human cells are protected from mitochondrial dysfunction by complementation of DNA products in fused mitochondria
-
DOI 10.1038/90116
-
T Ono K Isobe K Nakada JI Hayashi 2001 Human cells are protected from mitochondrial dysfunction by complementation of DNA products in fused mitochondria Nat. Genet. 28 272 275 11431699 1:CAS:528:DC%2BD3MXltFSmtLs%3D (Pubitemid 32626031)
-
(2001)
Nature Genetics
, vol.28
, Issue.3
, pp. 272-275
-
-
Ono, T.1
Isobe, K.2
Nakada, K.3
Hayashi, J.-I.4
-
9
-
-
0024146932
-
Biogenesis of mitochondria
-
G Attardi G Schatz 1988 Biogenesis of mitochondria Annu. Rev. Cell Biol. 4 289 333 2461720 1:CAS:528:DyaL1MXltlSitg%3D%3D (Pubitemid 19139259)
-
(1988)
Annual Review of Cell Biology
, vol.4
, pp. 289-333
-
-
Attardi, G.1
Schatz, G.2
-
11
-
-
27644566889
-
-
[in Russian], Meditsina, Moscow
-
G. N. Kryzhanovskii, I. N. Karaban', S. V. Magayeva, et al., Parkinson's Disease [in Russian], Meditsina, Moscow (2002).
-
(2002)
Parkinson's Disease
-
-
Kryzhanovskii, G.N.1
Karaban, I.N.2
Magayeva, S.V.3
-
12
-
-
76949097385
-
Gene therapy in Parkinson's disease: Rationale and current status
-
20155994 1:CAS:528:DC%2BC3cXlslCis70%3D
-
LR Feng KA Maguire-Zeiss 2010 Gene therapy in Parkinson's disease: rationale and current status CNS Drugs 24 177 192 20155994 1:CAS:528: DC%2BC3cXlslCis70%3D
-
(2010)
CNS Drugs
, vol.24
, pp. 177-192
-
-
Feng, L.R.1
Maguire-Zeiss, K.A.2
-
14
-
-
33646375711
-
High levels of mitochondrial DNA deletions in substantia nigra neurons in aging and Parkinson disease
-
16604074 1:CAS:528:DC%2BD28XjvVGksbs%3D
-
A Bender KJ Krishnan CM Morris, et al. 2006 High levels of mitochondrial DNA deletions in substantia nigra neurons in aging and Parkinson disease Nat. Genet. 38 515 517 16604074 1:CAS:528:DC%2BD28XjvVGksbs%3D
-
(2006)
Nat. Genet.
, vol.38
, pp. 515-517
-
-
Bender, A.1
Krishnan, K.J.2
Morris, C.M.3
-
15
-
-
37349004102
-
Parkinson's disease
-
1:CAS:528:DC%2BD2sXht1KntLfN
-
B Thomas MF Beal 2007 Parkinson's disease Human Mol. Genet. 16 R183 R194 1:CAS:528:DC%2BD2sXht1KntLfN
-
(2007)
Human Mol. Genet.
, vol.16
-
-
Thomas, B.1
Beal, M.F.2
-
16
-
-
33846636481
-
Progressive parkinsonism in mice with respiratory-chain-deficient dopamine neurons
-
DOI 10.1073/pnas.0605208103
-
MI Ekstrand M Terzioglu MP Dunne, et al. 2007 Progressive parkinsonism in mice with respiratory chain-deficient dopamine neurons Proc. Natl. Acad. Sci. USA 104 1325 1330 17227870 1:CAS:528:DC%2BD2sXht12itL0%3D (Pubitemid 46184003)
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.4
, pp. 1325-1330
-
-
Ekstrand, M.I.1
Terzioglu, M.2
Galter, D.3
Zhu, S.4
Hofstetter, C.5
Lindqvist, E.6
Thams, S.7
Bergstrand, A.8
Hansson, F.S.9
Trifunovic, A.10
Hoffer, B.11
Cullheim, S.12
Mohammed, A.H.13
Olson, L.14
Larsson, N.-G.15
-
17
-
-
44049099669
-
Mitochondrial import and accumulation of alphasynuclein impair complex i in human dopaminergic neuronal cultures and Parkinson disease brain
-
18245082 1:CAS:528:DC%2BD1cXjslyruro%3D
-
L Devi V Raghavendran BM Prabhu, et al. 2008 Mitochondrial import and accumulation of alphasynuclein impair complex I in human dopaminergic neuronal cultures and Parkinson disease brain J. Biol. Chem. 283 9089 9100 18245082 1:CAS:528:DC%2BD1cXjslyruro%3D
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 9089-9100
-
-
Devi, L.1
Raghavendran, V.2
Prabhu, B.M.3
-
18
-
-
33644778845
-
Parkin enhances mitochondrial biogenesis in proliferating cells
-
DOI 10.1093/hmg/ddl006
-
Y Kuroda T Mitsui M Kunishige, et al. 2006 Parkin enhances mitochondrial biogenesis in proliferating cells Human Mol. Genet. 15 883 895 1:CAS:528:DC%2BD28XitVGmsbk%3D (Pubitemid 43338230)
-
(2006)
Human Molecular Genetics
, vol.15
, Issue.6
, pp. 883-895
-
-
Kuroda, Y.1
Mitsui, T.2
Kunishige, M.3
Shono, M.4
Akaike, M.5
Azuma, H.6
Matsumoto, T.7
-
19
-
-
33745847479
-
Diagnosis and treatment of Parkinson disease: Molecules to medicine
-
JM Savitt VL Dawson TM Dawson 2006 Diagnosis and treatment of Parkinson disease: molecules to medicine J. Clin. Invest. 116 174 1754
-
(2006)
J. Clin. Invest.
, vol.116
, pp. 174-1754
-
-
Savitt, J.M.1
Dawson, V.L.2
Dawson, T.M.3
-
20
-
-
49349087497
-
PINK1 is necessary for long-term survival and mitochondrial function in human dopaminergic neurons
-
18560593
-
A Wood-Kaczmar S Gandhi Z Yao, et al. 2008 PINK1 is necessary for long-term survival and mitochondrial function in human dopaminergic neurons PLoS One 3 e2455 18560593
-
(2008)
PLoS One
, vol.3
, pp. 2455
-
-
Wood-Kaczmar, A.1
Gandhi, S.2
Yao, Z.3
-
21
-
-
49649097747
-
Loss of PINK1 causes mitochondrial functional defects and increased sensitivity to oxidative stress
-
18687901 1:CAS:528:DC%2BD1cXhtVSgsrnF
-
CA Gautier T Kitada J Shen 2008 Loss of PINK1 causes mitochondrial functional defects and increased sensitivity to oxidative stress Proc. Natl. Acad. Sci. USA 105 11364 11369 18687901 1:CAS:528:DC%2BD1cXhtVSgsrnF
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 11364-11369
-
-
Gautier, C.A.1
Kitada, T.2
Shen, J.3
-
22
-
-
34547885021
-
Drosophila overexpressing parkin R275W mutant exhibits dopaminergic neuron degeneration and mitochondrial abnormalities
-
DOI 10.1523/JNEUROSCI.0218-07.2007
-
C Wang R Lu X Ouyang, et al. 2007 Drosophila overexpressing parkin R275W mutant exhibits dopaminergic neuron degeneration and mitochondrial abnormalities J. Neurosci. 27 8563 8570 17687034 1:CAS:528:DC%2BD2sXptlSns7s%3D (Pubitemid 47254271)
-
(2007)
Journal of Neuroscience
, vol.27
, Issue.32
, pp. 8563-8570
-
-
Wang, C.1
Lu, R.2
Ouyang, X.3
Ho, M.W.L.4
Chia, W.5
Yu, F.6
Lim, K.-L.7
-
23
-
-
55749090654
-
The Parkinson's disease genes pink1 and parkin promote mitochondrial fission and/or inhibit fusion in Drosophila
-
18799731 1:CAS:528:DC%2BD1cXht1SgtrfL
-
H Deng MW Dodson H Huang M Guo 2008 The Parkinson's disease genes pink1 and parkin promote mitochondrial fission and/or inhibit fusion in Drosophila Proc. Natl. Acad. Sci. USA 105 14503 14508 18799731 1:CAS:528:DC%2BD1cXht1SgtrfL
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 14503-14508
-
-
Deng, H.1
Dodson, M.W.2
Huang, H.3
Guo, M.4
-
24
-
-
39449088321
-
The PINK1/Parkin pathway regulates mitochondrial morphology
-
DOI 10.1073/pnas.0709336105
-
AC Poole RE Thomas LA Andrews, et al. 2008 The PINK1/Parkin pathway regulates mitochondrial morphology Proc. Natl. Acad. Sci. USA 105 1638 1643 18230723 1:CAS:528:DC%2BD1cXhvFWktbo%3D (Pubitemid 351346567)
-
(2008)
Proceedings of the National Academy of Sciences of the United States of America
, vol.105
, Issue.5
, pp. 1638-1643
-
-
Poole, A.C.1
Thomas, R.E.2
Andrews, L.A.3
McBride, H.M.4
Whitworth, A.J.5
Pallanck, L.J.6
-
25
-
-
77951096150
-
Mitochondrial dynamics - Fusion, fission, movement and mitofagy - In neurodegenerative diseases
-
1:CAS:528:DC%2BD1MXhtlCqu7nN
-
H Chen DC Chan 2009 Mitochondrial dynamics - fusion, fission, movement and mitofagy - in neurodegenerative diseases Human Mol. Genet. 18 R169 R176 1:CAS:528:DC%2BD1MXhtlCqu7nN
-
(2009)
Human Mol. Genet.
, vol.18
-
-
Chen, H.1
Chan, D.C.2
-
26
-
-
67049171648
-
Neuronal protein trafficking associated with Alzheimer disease
-
BL Tang 2009 Neuronal protein trafficking associated with Alzheimer disease Cell Adhes. Migrat. 3 118 128
-
(2009)
Cell Adhes. Migrat.
, vol.3
, pp. 118-128
-
-
Tang, B.L.1
-
27
-
-
29144508843
-
Global prevalence of dementia: A Delphi consensus study
-
DOI 10.1016/S0140-6736(05)67889-0, PII S0140673605678890
-
CP Ferri M Prince C Brayne, et al. 2005 Alzheimer's disease international. Global prevalence of dementia: a Delphi consensus study Lancet 366 2112 2117 16360788 (Pubitemid 41797645)
-
(2005)
Lancet
, vol.366
, Issue.9503
, pp. 2112-2117
-
-
Ferri, C.P.1
Prince, M.2
Brayne, C.3
Brodaty, H.4
Fratiglioni, L.5
Ganguli, M.6
Hall, K.7
Hasegawa, K.8
Hendrie, H.9
Huang, Y.10
Jorm, A.11
Mathers, C.12
Menezes, P.R.13
Rimmer, E.14
Scazufca, M.15
-
28
-
-
0035341254
-
Mitochondrial abnormalities in Alzheimer's disease
-
K Hirai G Aliev A Nunomura, et al. 2001 Mitochondrial abnormalities in Alzheimer's disease J. Neurosci. 21 3017 3023 11312286 1:CAS:528: DC%2BD3MXjtFyqtbk%3D (Pubitemid 32323483)
-
(2001)
Journal of Neuroscience
, vol.21
, Issue.9
, pp. 3017-3023
-
-
Hirai, K.1
Aliev, G.2
Nunomura, A.3
Fujioka, H.4
Russell, R.L.5
Atwood, C.S.6
Johnson, A.B.7
Kress, Y.8
Vinters, H.V.9
Tabaton, M.10
Shimohama, S.11
Cash, A.D.12
Siedlak, S.L.13
Harris, P.L.R.14
Jones, P.K.15
Petersen, R.B.16
Perry, G.17
Smith, M.A.18
-
29
-
-
33646152108
-
Mitochondria are a direct site of A beta accumulation in Alzheimer's disease neurons: Implications for free radical generation and oxidative damage in disease progression
-
1:CAS:528:DC%2BD28XjslGhsLs%3D
-
M Manczak TS Anekonda E Henson, et al. 2006 Mitochondria are a direct site of A beta accumulation in Alzheimer's disease neurons: implications for free radical generation and oxidative damage in disease progression Human Mol. Genet. 15 1437 1449 1:CAS:528:DC%2BD28XjslGhsLs%3D
-
(2006)
Human Mol. Genet.
, vol.15
, pp. 1437-1449
-
-
Manczak, M.1
Anekonda, T.S.2
Henson, E.3
-
30
-
-
0037017399
-
1-42 through p53 and Bax in cultured primary human neurons
-
DOI 10.1083/jcb.200110119
-
Y Zhang R McLaughlin C Goodyear A LeBlanc 2002 Selective cytotoxicity of intracellular amyloid-β peptide 1-42 through p53 and Bax in cultured primary human neurons J. Cell Biol. 156 519 529 11815632 1:CAS:528: DC%2BD38XhtVOqtLw%3D (Pubitemid 34839899)
-
(2002)
Journal of Cell Biology
, vol.156
, Issue.3
, pp. 519-529
-
-
Zhang, Y.1
McLaughlin, R.2
Goodyer, C.3
LeBlanc, A.4
-
31
-
-
27144447811
-
Sequence determinants of enhanced amyloidogenicity of Alzheimer Aβ42 peptide relative to Aβ40
-
DOI 10.1074/jbc.M505763200
-
W Kim MH Hecht 2005 Sequence determinants of enhanced amyloidogenicity of Alzheimer Aβ42 peptide relative to Aβ40 J. Biol. Chem. 280 35069 35076 16079141 1:CAS:528:DC%2BD2MXhtVyks7jI (Pubitemid 41504642)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.41
, pp. 35069-35076
-
-
Kim, W.1
Hecht, M.H.2
-
32
-
-
11144353586
-
ABAD Directly Links Aβ to Mitochondrial Toxicity in Alzheimer's Disease
-
DOI 10.1126/science.1091230
-
JW Lustbader M Cirilli C Lin, et al. 2004 ABAD directly links Abeta to mitochondrial toxicity in Alzheimer's disease Science 304 448 452 15087549 1:CAS:528:DC%2BD2cXjtVWksrg%3D (Pubitemid 38495942)
-
(2004)
Science
, vol.304
, Issue.5669
, pp. 448-452
-
-
Lustbader, J.W.1
Cirilli, M.2
Lin, C.3
Xu, H.W.4
Takuma, K.5
Wang, N.6
Caspersen, C.7
Chen, X.8
Pollak, S.9
Chaney, M.10
Trinchese, F.11
Liu, S.12
Gunn-Moore, F.13
Lue, L.-F.14
Walker, D.G.15
Kappasamy, P.16
Zewier, Z.L.17
Arancio, O.18
Stern, D.19
Yan, S.S.D.20
Wu, H.21
more..
-
33
-
-
77449115085
-
Mitochondrial accumulation of APP and Abeta: Significance for Alzheimer's disease pathogenesis
-
19725915 1:CAS:528:DC%2BC3cXislansL0%3D
-
PF Pavlov C Hansson Petersen E Glaser M Ancarkrona 2009 Mitochondrial accumulation of APP and Abeta: significance for Alzheimer's disease pathogenesis J. Cell. Mol. Med. 13 4137 4145 19725915 1:CAS:528:DC%2BC3cXislansL0%3D
-
(2009)
J. Cell. Mol. Med.
, vol.13
, pp. 4137-4145
-
-
Pavlov, P.F.1
Hansson Petersen, C.2
Glaser, E.3
Ancarkrona, M.4
-
34
-
-
0033990169
-
Presenilins and Alzheimer's disease: Biological functions and pathogenic mechanism
-
C Czesh G Tremp L Pradier 2000 Presenilins and Alzheimer's disease: biological functions and pathogenic mechanism Prog. Neurobiol. 60 363 384
-
(2000)
Prog. Neurobiol.
, vol.60
, pp. 363-384
-
-
Czesh, C.1
Tremp, G.2
Pradier, L.3
-
35
-
-
0037687629
-
Amyloid precursor protein gene mutations reponsible for early-onset autosomal dominant Alzheimer's disease
-
A Kowalska 2003 Amyloid precursor protein gene mutations responsible for early-onset autosomal dominant Alzheimer's disease Folia Neuropathol. 41 35 40 12862394 1:CAS:528:DC%2BD3sXnvVSkur8%3D (Pubitemid 36582031)
-
(2003)
Folia Neuropathologica
, vol.41
, Issue.1
, pp. 35-40
-
-
Kowalska, A.1
-
36
-
-
16044366039
-
Increased amyloid-β42(43) in brains of mice expressing mutant presenilin 1
-
DOI 10.1038/383710a0
-
K Duff C Eckman C Zehr, et al. 1996 Increased amyloid-β42(43) in brains of mice expressing mutant presenilin 1 Nature 383 710 713 8878479 1:CAS:528:DyaK28XmsVGnsrs%3D (Pubitemid 26360645)
-
(1996)
Nature
, vol.383
, Issue.6602
, pp. 710-713
-
-
Duff, K.1
Eckman, C.2
Zehr, C.3
Yu, X.4
Prada, C.-M.5
Perez-Tur, J.6
Hutton, M.7
Buee, L.8
Harigaya, Y.9
Yager, D.10
Morgan, D.11
Gordon, M.N.12
Holcomb, L.13
Refolo, L.14
Zenk, B.15
Hardy, J.16
Younkin, S.17
-
37
-
-
16944362157
-
Mutant presenilins of Alzheimer's disease increase production of 42-residue amyloid β-protein in both transfected cells and transgenic mice
-
DOI 10.1038/nm0197-67
-
M Citron D Westaway W Xia, et al. 1997 Mutant presenilins of Alzheimer's disease increase production of 42-residue amyloid beta-protein in both transfected cells and transgenic mice Nat. Med. 3 67 72 8986743 1:CAS:528:DyaK2sXitFOrtg%3D%3D (Pubitemid 27019143)
-
(1997)
Nature Medicine
, vol.3
, Issue.1
, pp. 67-72
-
-
Citron, M.1
Westaway, D.2
Xia, W.3
Carlson, G.4
Diehl, T.5
Levesque, G.6
Johnson-Wood, K.7
Lee, M.8
Seubert, P.9
Davis, A.10
Kholodenko, D.11
Motter, R.12
Sherrington, R.13
Perry, B.14
Yao, H.15
Strome, R.16
Lieberburg, I.17
Rommens, J.18
Kim, S.19
Schenk, D.20
Fraser, P.21
St. George Hyslop, P.22
Selkoe, D.J.23
more..
-
38
-
-
0027933135
-
Marked changes in mitochondrial DNA deletion levels in Alzheimer brains
-
DOI 10.1006/geno.1994.1525
-
M Corral-Debrinski T Horton MT Lott, et al. 1994 Marked changes in mitochondrial DNA deletion levels in Alzheimer's brain Genomics 23 471 476 7835898 1:CAS:528:DyaK2cXmslyjsL0%3D (Pubitemid 24308270)
-
(1994)
Genomics
, vol.23
, Issue.2
, pp. 471-476
-
-
Corral-Debrinski, M.1
Horton, T.2
Lott, M.T.3
Shoffner, J.M.4
McKee, A.C.5
Beal, M.F.6
Graham, B.H.7
Wallace, D.C.8
-
39
-
-
67650732998
-
Impaired balance of mitochondrial fission and fusion in Alzheimer's disease
-
19605646 1:CAS:528:DC%2BD1MXovFegu78%3D
-
X Wang B Su HG Lee, et al. 2009 Impaired balance of mitochondrial fission and fusion in Alzheimer's disease J. Neurosci. 29 9090 9103 19605646 1:CAS:528:DC%2BD1MXovFegu78%3D
-
(2009)
J. Neurosci.
, vol.29
, pp. 9090-9103
-
-
Wang, X.1
Su, B.2
Lee, H.G.3
-
40
-
-
58049218922
-
Amyloidbeta overproduction causes abnormal mitochondrial dynamics via differential modulation of mitochondrial fission/fusion proteins
-
19050078 1:CAS:528:DC%2BD1cXhsFamu73E
-
X Wang B Su SL Siedlak, et al. 2008 Amyloidbeta overproduction causes abnormal mitochondrial dynamics via differential modulation of mitochondrial fission/fusion proteins Proc. Natl. Acad. Sci. USA 105 19318 19323 19050078 1:CAS:528:DC%2BD1cXhsFamu73E
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 19318-19323
-
-
Wang, X.1
Su, B.2
Siedlak, S.L.3
-
41
-
-
0025024024
-
Cytochrome oxidase deficiency in Alzheimer's disease
-
WD Parker Jr CM Filley JK Parks 1990 Cytochrome oxidase deficiency in Alzheimer's disease Neurology 40 1302 1303 2166249 (Pubitemid 20244999)
-
(1990)
Neurology
, vol.40
, Issue.8
, pp. 1302-1303
-
-
Parker Jr., W.D.1
Filley, C.M.2
Parks, J.K.3
-
42
-
-
0031737226
-
Abnormalities of mitochondrial enzymes in Alzheimer disease
-
DOI 10.1007/s007020050099
-
GE Gibson KF Sheu JP Blass 1998 Abnormalities of mitochondrial enzymes in Alzheimer disease J. Neural Transm. 105 855 870 9869323 1:CAS:528: DyaK1MXhsVOltg%3D%3D (Pubitemid 28539834)
-
(1998)
Journal of Neural Transmission
, vol.105
, Issue.8-9
, pp. 855-870
-
-
Gibson, G.E.1
Sheu, K.-F.R.2
Blass, J.P.3
-
43
-
-
0042388101
-
Cerebrometabolic abnormalities in Alzheimer's disease
-
DOI 10.1179/016164103101201995
-
JP Blass 2003 Cerebrometabolic abnormalities in Alzheimer's disease Neurol. Res. 25 556 566 14503009 1:CAS:528:DC%2BD3sXnvF2ntbY%3D (Pubitemid 37087599)
-
(2003)
Neurological Research
, vol.25
, Issue.6
, pp. 556-566
-
-
Blass, J.P.1
-
44
-
-
0026718966
-
Brain cytochrome oxidase in Alzheimer's disease
-
1321237 1:CAS:528:DyaK38Xlt12ht7o%3D
-
SJ Kish C Bergeron A Rajput, et al. 1992 Brain cytochrome oxidase in Alzheimer's disease J. Neurochem. 59 776 779 1321237 1:CAS:528: DyaK38Xlt12ht7o%3D
-
(1992)
J. Neurochem.
, vol.59
, pp. 776-779
-
-
Kish, S.J.1
Bergeron, C.2
Rajput, A.3
-
45
-
-
0348111546
-
Cytochrome c oxidase is decreased in Alzheimer's disease platelets
-
DOI 10.1016/S0197-4580(03)00033-2
-
SM Cardoso MT Proenca S Santos, et al. 2004 Cytochrome c oxidase is decreased in Alzheimer's disease platelets Neurobiol. Aging 25 105 110 14675736 1:CAS:528:DC%2BD3sXpvVaitL0%3D (Pubitemid 37522198)
-
(2004)
Neurobiology of Aging
, vol.25
, Issue.1
, pp. 105-110
-
-
Cardoso, S.M.1
Proenca, M.T.2
Santos, S.3
Santana, I.4
Oliveira, C.R.5
-
46
-
-
70349422148
-
Role of mitochondrial dysfunction in the pathogenesis of Huntington's disease
-
19622387 1:CAS:528:DC%2BD1MXht1WqtbfN
-
RA Quintanilla GVW Johnson 2009 Role of mitochondrial dysfunction in the pathogenesis of Huntington's disease Brain Res. Bull. 80 242 247 19622387 1:CAS:528:DC%2BD1MXht1WqtbfN
-
(2009)
Brain Res. Bull.
, vol.80
, pp. 242-247
-
-
Quintanilla, R.A.1
Johnson, G.V.W.2
-
47
-
-
17144464097
-
Huntington disease. A review
-
10961047 1:STN:280:DC%2BD3cvpt1aqtA%3D%3D
-
E Bonilla 2000 Huntington disease. A review Invest. Clin. 41 117 141 10961047 1:STN:280:DC%2BD3cvpt1aqtA%3D%3D
-
(2000)
Invest. Clin.
, vol.41
, pp. 117-141
-
-
Bonilla, E.1
-
48
-
-
33750322830
-
Cellular and molecular mechanisms involved in the selective vulnerability of striatal projection neurons in Huntington's disease
-
E Perez-Navarro JM Canals S Gines J Alberch 2006 Cellular and molecular mechanisms involved in the selective vulnerability of striatal projection neurons in Huntington disease Histol. Histopathol. 21 1217 1232 16874665 1:CAS:528:DC%2BD28Xhtlant7nK (Pubitemid 44614504)
-
(2006)
Histology and Histopathology
, vol.21
, Issue.10-12
, pp. 1217-1232
-
-
Perez-Navarro, E.1
Canals, J.M.2
Gines, S.3
Alberch, J.4
-
49
-
-
0030752709
-
Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain
-
DOI 10.1126/science.277.5334.1990
-
M DiFiglia E Sapp KO Chase, et al. 1997 Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neuritis in brain Science 277 1990 1993 9302293 1:CAS:528:DyaK2sXmt12rurs%3D (Pubitemid 27449140)
-
(1997)
Science
, vol.277
, Issue.5334
, pp. 1990-1993
-
-
DiFiglia, M.1
Sapp, E.2
Chase, K.O.3
Davies, S.W.4
Bates, G.P.5
Vonsattel, J.P.6
Aronin, N.7
-
50
-
-
0036403826
-
Pyramidal cell loss in motor cortices in Huntington's disease
-
DOI 10.1006/nbdi.2002.0528
-
V Macdonald G Halliday 2002 Pyramidal cell loss in motor cortices in Huntington's disease Neurobiol. Dis. 10 378 386 12270698 (Pubitemid 35217589)
-
(2002)
Neurobiology of Disease
, vol.10
, Issue.3
, pp. 378-386
-
-
Macdonald, V.1
Halliday, G.2
-
51
-
-
1242338856
-
Huntingtin-protein interactions and the pathogenesis of Huntington's disease
-
15036808
-
SH Li XJ Li 2004 Huntingtin-protein interactions and the pathogenesis of Huntington's disease Trends Genet. 20 146 154 15036808
-
(2004)
Trends Genet.
, vol.20
, pp. 146-154
-
-
Li, S.H.1
Li, X.J.2
-
52
-
-
0028234787
-
CAG repeat size and clinical presentation in Huntington's disease
-
T Ashizawa LJ Wong CS Richards, et al. 1997 CAG repeat size and clinical presentation in Huntington's disease Neurology 44 1137 1143
-
(1997)
Neurology
, vol.44
, pp. 1137-1143
-
-
Ashizawa, T.1
Wong, L.J.2
Richards, C.S.3
-
53
-
-
0023865274
-
Clinical and neuropathologic assessment of severity in Huntington's disease
-
RH Myers JP Vonsatell TJ Stevens, et al. 1988 Clinical and neuropathologic assessment of severity of Huntington's disease Neurology 38 341 347 2964565 1:STN:280:DyaL1c7lslWiuw%3D%3D (Pubitemid 18083664)
-
(1988)
Neurology
, vol.38
, Issue.3
, pp. 341-347
-
-
Myers, R.H.1
Vonsattel, J.P.2
Stevens, T.J.3
Cupples, L.A.4
Richardson, E.P.5
Martin, J.B.6
Bird, E.D.7
-
54
-
-
0029068332
-
NMDA receptor subunit mRNA expression by projection neurons and interneurons in rat striatum
-
7623152 1:CAS:528:DyaK2MXmvFCrsbw%3D
-
GB Landwehrmeyer DG Standaert CM Testa, et al. 1995 NMDA receptor subunit mRNA expression by projection neurons and interneurons in rat striatum J. Neurosci. 15 5297 5307 7623152 1:CAS:528:DyaK2MXmvFCrsbw%3D
-
(1995)
J. Neurosci.
, vol.15
, pp. 5297-5307
-
-
Landwehrmeyer, G.B.1
Standaert, D.G.2
Testa, C.M.3
-
55
-
-
0027741301
-
1H NMR spectroscopy
-
BG Jenkins WJ Koroshetz MF Beal BR Rosen 1993 Evidence for impairment of energy metabolism in vivo in Huntington's disease using localized 1H NMR spectroscopy Neurology 43 2689 2695 8255479 1:STN:280:DyaK2c%2FnslCjsw%3D%3D (Pubitemid 24004570)
-
(1993)
Neurology
, vol.43
, Issue.12
, pp. 2689-2695
-
-
Jenkins, B.G.1
Koroshetz, W.J.2
Beal, M.F.3
Rosen, B.R.4
-
56
-
-
0033914747
-
Abnormal in vivo skeletal muscle energy metabolism in Huntington's disease and dentatorubropallidoluysian atrophy
-
DOI 10.1002/1531-8249(200007)48:1<72::AID-ANA11>3.0.CO;2-I
-
R Lodi AH Schapira D Manners, et al. 2000 Abnormal in vivo skeletal muscle energy metabolism in Huntington's disease and dentatorubropallidoluysian atrophy Ann. Neurol. 48 72 76 10894218 1:STN:280:DC%2BD3czltVOitA%3D%3D (Pubitemid 30432433)
-
(2000)
Annals of Neurology
, vol.48
, Issue.1
, pp. 72-76
-
-
Lodi, R.1
Schapira, A.H.V.2
Manners, D.3
Styles, P.4
Wood, N.W.5
Taylor, D.J.6
Warner, T.T.7
-
57
-
-
0029875381
-
Mitochondrial defect in Huntington's disease caudate nucleus
-
DOI 10.1002/ana.410390317
-
M Gu MT Gash VM Mann, et al. 1996 Mitochondrial defect in Huntington's disease caudate nucleus Ann. Neurol. 39 385 389 8602759 1:CAS:528: DyaK28XisFyrsbo%3D (Pubitemid 26100764)
-
(1996)
Annals of Neurology
, vol.39
, Issue.3
, pp. 385-389
-
-
Gu, M.1
Gash, M.T.2
Mann, V.M.3
Javoy-Agid, F.4
Cooper, J.M.5
Schapira, A.H.V.6
-
58
-
-
0032900574
-
Biochemical abnormalities and excitotoxicity in Huntington's disease brain
-
DOI 10.1002/1531-8249(199901)45:1<25::AID-ART6>3.0.CO;2-E
-
SJ Tabrizi MW Cleeter J Xuereb, et al. 1999 Biochemical abnormalities and excitotoxicity in Huntington's disease brain Ann. Neurol. 45 25 32 9894873 1:CAS:528:DyaK1MXhtV2jsL0%3D (Pubitemid 29036428)
-
(1999)
Annals of Neurology
, vol.45
, Issue.1
, pp. 25-32
-
-
Tabrizi, S.J.1
Cleeter, M.W.J.2
Xuereb, J.3
Taanman, J.-W.4
Cooper, J.M.5
Schapira, A.H.V.6
-
59
-
-
0033032999
-
Mitochondrial involvement in Parkinson's disease, Huntington's disease, hereditary spastic paraplegia and Friedreich's ataxia
-
DOI 10.1016/S0005-2728(98)00164-9, PII S0005272898001649
-
AH Schapira 1999 Mitochondrial involvement in Parkinson's disease, Huntington's disease, hereditary spastic paraplegia and Friedreich's ataxia Biochim. Biophys. Acta 1410 159 170 10076024 1:STN:280:DyaK1M7nslCltA%3D%3D (Pubitemid 29078602)
-
(1999)
Biochimica et Biophysica Acta - Bioenergetics
, vol.1410
, Issue.2
, pp. 159-170
-
-
Schapira, A.H.V.1
-
60
-
-
0027433553
-
Neurochemical and histologic characterization of striatal excitotoxic lesions produced by the mitochondrial toxin 3-nitropropionic acid
-
MF Beal E Brouilett BG Jenkins, et al. 1993 Neurochemical and histological characterization of striatal excitotoxic lesions produced by the mitochondrial toxin 3-nitropropionic acid J. Neurosci. 13 4181 4192 7692009 1:CAS:528:DyaK3sXms1CgtLc%3D (Pubitemid 23299942)
-
(1993)
Journal of Neuroscience
, vol.13
, Issue.10
, pp. 4181-4192
-
-
Beal, M.F.1
Brouillet, E.2
Jenkins, B.G.3
Ferrante, R.J.4
Kowall, N.W.5
Miller, J.M.6
Storey, E.7
Srivastava, R.8
Rosen, B.R.9
Hyman, B.T.10
-
61
-
-
0029118136
-
Chronic mitochondrial energy impairment produces selective striatal degeneration and abnormal choreiform movements in primates
-
E Brouilett P Hantraye RJ Ferrante, et al. 1995 Chronic mitochondrial energy impairment produces selective striatal degeneration and abnormal choreiform movements in primates Proc. Natl. Acad. Sci. USA 92 7105 7109
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 7105-7109
-
-
Brouilett, E.1
Hantraye, P.2
Ferrante, R.J.3
-
62
-
-
0032851595
-
Increased apoptosis of Huntington disease lymphoblasts associated with repeat length-dependent mitochondrial depolarization
-
DOI 10.1038/13518
-
A Sawa GW Wiegand J Cooper, et al. 1999 Increased apoptosis of Huntington's disease lymphoblasts associated with repeat length-dependent mitochondrial depolarization Nat. Med. 5 1194 1198 10502825 1:CAS:528: DyaK1MXms1Wkt7w%3D (Pubitemid 29474426)
-
(1999)
Nature Medicine
, vol.5
, Issue.10
, pp. 1194-1198
-
-
Sawa, A.1
Wiegand, G.W.2
Cooper, J.3
Margolis, R.L.4
Sharp, A.H.5
Lawler Jr., J.F.6
Greenamyre, J.T.7
Snyder, S.H.8
Ross, C.A.9
-
63
-
-
0036327065
-
Early mitochondrial calcium defects in Huntington's disease are a direct effect of polyglutamines
-
DOI 10.1038/nn884
-
AV Panov CA Gutekunst BR Leavitt, et al. 2002 Early mitochondrial calcium defects in Huntington's disease are direct effects of polyglutamines Nat. Neurosci. 5 731 736 12089530 1:CAS:528:DC%2BD38XlsFaqu7g%3D (Pubitemid 34827590)
-
(2002)
Nature Neuroscience
, vol.5
, Issue.8
, pp. 731-736
-
-
Panov, A.V.1
Gutekunst, C.-A.2
Leavitt, B.R.3
Hayden, M.R.4
Burke, J.R.5
Strittmatter, W.J.6
Greenamyre, J.T.7
-
64
-
-
0034702030
-
Decreased expression of striatal signaling genes in a mouse model of Huntington's disease
-
R Luthi-Carter A Strand NL Peters, et al. 2000 Decreased expression of striatal signaling genes in a mouse model of Huntington's disease Human Mol. Genet. 9 1259 1271 1:CAS:528:DC%2BD3cXjvFynu7o%3D (Pubitemid 30312475)
-
(2000)
Human Molecular Genetics
, vol.9
, Issue.9
, pp. 1259-1271
-
-
Luthi-Carter, R.1
Strand, A.2
Peters, N.L.3
Solano, S.M.4
Hollingsworth, Z.R.5
Menon, A.S.6
Frey, A.S.7
Spektor, B.S.8
Penney, E.B.9
Schilling, G.10
Ross, C.A.11
Borchelt, D.R.12
Tapscott, S.J.13
Young, A.B.14
Cha, J.-H.J.15
Olson, J.M.16
-
65
-
-
33749042331
-
Transcriptional Repression of PGC-1α by Mutant Huntingtin Leads to Mitochondrial Dysfunction and Neurodegeneration
-
DOI 10.1016/j.cell.2006.09.015, PII S0092867406012050
-
L Cui H Jeong F Borovecki, et al. 2006 Transcriptional repression of PGC-1alpha by mutant huntingtin leads to mitochondrial dysfunction and neurodegeneration Cell 127 59 69 17018277 1:CAS:528:DC%2BD28XhtFSitr%2FP (Pubitemid 44466642)
-
(2006)
Cell
, vol.127
, Issue.1
, pp. 59-69
-
-
Cui, L.1
Jeong, H.2
Borovecki, F.3
Parkhurst, C.N.4
Tanese, N.5
Krainc, D.6
-
66
-
-
0035805504
-
Huntingtin's neuroprotective activity occurs via inhibition of procaspase-9 processing
-
11278258 1:CAS:528:DC%2BD3MXjs1Okt7Y%3D
-
D Rigamonti S Sipione D Goffredo, et al. 2001 Huntingtin's neuroprotective activity occurs via inhibition of procaspase-9 processing J. Biol. Chem. 276 14545 14548 11278258 1:CAS:528:DC%2BD3MXjs1Okt7Y%3D
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 14545-14548
-
-
Rigamonti, D.1
Sipione, S.2
Goffredo, D.3
-
67
-
-
0036048873
-
Cytochrome C and caspase-9 expression in Huntington's disease
-
DOI 10.1385/NMM:1:3:183
-
T Kiechle A Dedeoglu J Kibulis, et al. 2002 Cytochrome c and caspase-9 expression in Huntington's disease Neuromol. Med. 1 183 195 1:CAS:528: DC%2BD38XltVyht7c%3D (Pubitemid 37012515)
-
(2002)
NeuroMolecular Medicine
, vol.1
, Issue.3
, pp. 183-195
-
-
Kiechle, T.1
Dedeoglu, A.2
Kubilus, J.3
Kowall, N.W.4
Beal, M.F.5
Friedlander, R.M.6
Hersch, S.M.7
Ferrante, R.J.8
-
69
-
-
84856815851
-
Perspectives on molecular targeted therapies and clinical trials for neurodegenerative diseases
-
M Katsuno F Tanaki G Sobue 2012 Perspectives on molecular targeted therapies and clinical trials for neurodegenerative diseases J. Neurol., Neurosurg., Psychiat. 83 329 335
-
(2012)
J. Neurol., Neurosurg., Psychiat.
, vol.83
, pp. 329-335
-
-
Katsuno, M.1
Tanaki, F.2
Sobue, G.3
-
70
-
-
66749102059
-
Redox modifier genes and pathways in amyotrophic lateral sclerosis
-
1:CAS:528:DC%2BD1MXmsVCmt7s%3D
-
BJ Carter P Anklesaria S Choi JF Engelhardt 2009 Redox modifier genes and pathways in amyotrophic lateral sclerosis Antioxidants Redox Signal. 11 1569 1586 1:CAS:528:DC%2BD1MXmsVCmt7s%3D
-
(2009)
Antioxidants Redox Signal.
, vol.11
, pp. 1569-1586
-
-
Carter, B.J.1
Anklesaria, P.2
Choi, S.3
Engelhardt, J.F.4
-
72
-
-
0034031598
-
Molecular factors underlying selective vulnerability of motor neurons to neurodegeneration in amyotrophic lateral sclerosis
-
PJ Shaw CJ Eggett 2000 Molecular factors underlying selective vulnerability of motor neurons to neurodegeneration in amyotrophic lateral sclerosis J. Neurol. 247 17 27 (Pubitemid 30182083)
-
(2000)
Journal of Neurology, Supplement
, vol.247
, Issue.1
, pp. 17-27
-
-
Shaw, P.J.1
Eggett, C.J.2
-
73
-
-
15844393658
-
Motor neurons in Cu/Zn superoxide dismutase-deficient mice develop normally but exhibit enhanced cell death after axonal injury
-
DOI 10.1038/ng0596-43
-
AG Reaume JL Elliott EK Hoffmann, et al. 1996 Motor neurons in Cu/Zn superoxide dismutase-deficient mice develop normally but exhibit enhanced death after axonal injury Nat. Genet. 13 43 47 8673102 1:CAS:528:DyaK28XksVWgtbs%3D (Pubitemid 26139292)
-
(1996)
Nature Genetics
, vol.13
, Issue.1
, pp. 43-47
-
-
Reaume, A.G.1
Elliott, J.L.2
Hoffman, E.K.3
Kowall, N.W.4
Ferrante, R.J.5
Siwek, D.F.6
Wilcox, H.M.7
Flood, D.G.8
Beal, M.F.9
Brown Jr., R.H.10
Scott, R.W.11
Snider, W.D.12
-
74
-
-
79952486262
-
Amyotrophic lateral sclerosis
-
21296405 1:CAS:528:DC%2BC3MXjtFWgsL8%3D
-
MC Kiernan S Vucic BC Cheah, et al. 2011 Amyotrophic lateral sclerosis Lancet 377 942 955 21296405 1:CAS:528:DC%2BC3MXjtFWgsL8%3D
-
(2011)
Lancet
, vol.377
, pp. 942-955
-
-
Kiernan, M.C.1
Vucic, S.2
Cheah, B.C.3
-
75
-
-
66749104344
-
Mitochondrial function, morphology, and axonal transport in amyotrophic lateral sclerosis
-
1:CAS:528:DC%2BD1MXmsVCmtrk%3D
-
J Magrane G Manfredi 2009 Mitochondrial function, morphology, and axonal transport in amyotrophic lateral sclerosis Antioxidants Redox Signal. 11 1615 1626 1:CAS:528:DC%2BD1MXmsVCmtrk%3D
-
(2009)
Antioxidants Redox Signal.
, vol.11
, pp. 1615-1626
-
-
Magrane, J.1
Manfredi, G.2
-
76
-
-
33846087291
-
Mitochondrial alterations in the spinal cord of patients with sporadic amyotrophic lateral sclerosis
-
DOI 10.1097/nen.0b013e31802c396b, PII 0000507220070100000002
-
S Sasaki M Iwata 2007 Mitochondrial alterations in the spinal cord of patients with sporadic amyotrophic lateral sclerosis J. Neuropathol. Exp. Neurol. 66 10 16 17204932 (Pubitemid 46066784)
-
(2007)
Journal of Neuropathology and Experimental Neurology
, vol.66
, Issue.1
, pp. 10-16
-
-
Sasaki, S.1
Iwata, M.2
-
77
-
-
0023270442
-
Hepatic ultrastructural changes and liver dysfunction in amyotrophic lateral sclerosis
-
3800708 1:STN:280:DyaL2s%2FpvFCgsw%3D%3D
-
Y Nakano K Hirayama K Terao 1987 Hepatic ultrastructural changes and liver dysfunction in amyotrophic lateral sclerosis Arch. Neurol. 44 103 104 3800708 1:STN:280:DyaL2s%2FpvFCgsw%3D%3D
-
(1987)
Arch. Neurol.
, vol.44
, pp. 103-104
-
-
Nakano, Y.1
Hirayama, K.2
Terao, K.3
-
78
-
-
0032539791
-
Impairment of mitochondrial function in skeletal muscle of patients with amyotrophic lateral sclerosis
-
DOI 10.1016/S0022-510X(98)00008-2, PII S0022510X98000082
-
FR Weidemann K Winkler AV Kuznetsov, et al. 1998 Impairment of mitochondrial function in skeletal muscles of patients with amyotrophic lateral sclerosis J. Neurol. Sci. 156 65 72 (Pubitemid 28141041)
-
(1998)
Journal of the Neurological Sciences
, vol.156
, Issue.1
, pp. 65-72
-
-
Wiedemann, F.R.1
Winkler, K.2
Kuznetsov, A.V.3
Bartels, C.4
Vielhaber, S.5
Feistner, H.6
Kunz, W.S.7
-
79
-
-
0029809528
-
Amyotrophic lateral sclerosis: Oxidative energy metabolism and calcium homeostasis in peripheral blood lymphocytes
-
8857745 1:STN:280:DyaK2s%2FhtVOisA%3D%3D
-
D Curti A Malaspina G Facchetti, et al. 1996 Amyotrophic lateral sclerosis: oxidative energy metabolism and calcium homeostasis in peripheral blood lymphocytes Neurology 47 1060 1064 8857745 1:STN:280: DyaK2s%2FhtVOisA%3D%3D
-
(1996)
Neurology
, vol.47
, pp. 1060-1064
-
-
Curti, D.1
Malaspina, A.2
Facchetti, G.3
-
80
-
-
0028933344
-
Neuropathological changes in two lines of mice carrying transgene for mutant human Cu, Zn SOD and in mice overexpressing wild-type human SOD: A model of familial amyotrophic lateral sclerosis (FALS)
-
7796176 1:CAS:528:DyaK2MXks1Khtrk%3D
-
MC Dal Canto ME Gurney 1995 Neuropathological changes in two lines of mice carrying transgene for mutant human Cu, Zn SOD and in mice overexpressing wild-type human SOD: a model of familial amyotrophic lateral sclerosis (FALS) Brain Res. 676 25 40 7796176 1:CAS:528:DyaK2MXks1Khtrk%3D
-
(1995)
Brain Res.
, vol.676
, pp. 25-40
-
-
Dal Canto, M.C.1
Gurney, M.E.2
-
81
-
-
0029053881
-
An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria
-
7605627 1:CAS:528:DyaK2MXms1Wrtr8%3D
-
PC Wong CA Pardo DR Borchelt, et al. 1995 An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria Neuron 14 1105 1116 7605627 1:CAS:528:DyaK2MXms1Wrtr8%3D
-
(1995)
Neuron
, vol.14
, pp. 1105-1116
-
-
Wong, P.C.1
Pardo, C.A.2
Borchelt, D.R.3
-
82
-
-
33748261830
-
Complete dissociation of motor neuron death from motor dysfunction by Bax deletion in a mouse model of ALS
-
DOI 10.1523/JNEUROSCI.2315-06.2006
-
TW Gould RR Buss S Vinsant, et al. 2006 Complete dissociation of motor neuron death from motor dysfunction by Bax deletion in a mouse model of ALS J. Neurosci. 26 8774 8786 16928866 1:CAS:528:DC%2BD28Xpt1SrsrY%3D (Pubitemid 44319413)
-
(2006)
Journal of Neuroscience
, vol.26
, Issue.34
, pp. 8774-8786
-
-
Gould, T.W.1
Buss, R.R.2
Vinsant, S.3
Prevette, D.4
Sun, W.5
Knudson, C.M.6
Milligan, C.E.7
Oppenheim, R.W.8
-
83
-
-
3242875557
-
Axonal mitochondrial transport and potential are correlated
-
DOI 10.1242/jcs.01130
-
KE Miller MP Sheetz 2004 Axonal mitochondrial transport and potential are correlated J. Cell Sci. 117 2791 2804 15150321 1:CAS:528:DC%2BD2cXlvFeht7c%3D (Pubitemid 38997261)
-
(2004)
Journal of Cell Science
, vol.117
, Issue.13
, pp. 2791-2804
-
-
Miller, K.E.1
Sheetz, M.P.2
-
84
-
-
0034821922
-
CuZn superoxide dismutase (SOD1) accumulates in vacuolated mitochondria in transgenic mice expressing amyotrophic lateral sclerosis-linked SOD1 mutations
-
D Jaarsma F Rognoni W van Duijn, et al. 2001 Cu, Zn superoxide dismutase (SOD1) accumulates in vacuolated mitochondria in transgenic mice expressing amyotrophic lateral sclerosis-linked mutations Acta Neuropathol. Berl. 102 293 305 11603803 1:CAS:528:DC%2BD3MXmsFWgsro%3D (Pubitemid 32894698)
-
(2001)
Acta Neuropathologica
, vol.102
, Issue.4
, pp. 293-305
-
-
Jaarsma, D.1
Rognoni, F.2
Van Duijn, W.3
Verspaget, H.W.4
Haasdijk, E.D.5
Holstege, J.C.6
-
85
-
-
3242703300
-
Amyotrophic lateral sclerosis-associated SOD1 mutant proteins bind and aggregate with Bcl-2 in spinal cord mitochondria
-
DOI 10.1016/j.neuron.2004.06.021, PII S0896627304003915
-
P Pasinelli ME Belford N Lennon, et al. 2004 Amyotrophic lateral sclerosis-associated SOD1 mutant proteins bind and aggregate with Bcl-2 in spinal cord mitochondria Neuron 43 19 30 15233914 1:CAS:528:DC%2BD2cXmtVyjs7g%3D (Pubitemid 38952816)
-
(2004)
Neuron
, vol.43
, Issue.1
, pp. 19-30
-
-
Pasinelli, P.1
Belford, M.E.2
Lennon, N.3
Bacskai, B.J.4
Hyman, B.T.5
Trotti, D.6
Brown Jr., R.H.7
-
86
-
-
0032896327
-
Neuronal death in amyotrophic lateral sclerosis is apoptosis: Possible contribution of a programmed cell death mechanism
-
LJ Martin 1999 Neuronal death in amyotrophic lateral sclerosis is apoptosis: possible contribution of programmed cell death mechanism J. Neuropathol. Exp. Neurol. 58 459 471 10331434 1:STN:280:DyaK1M3mtVaktQ%3D%3D (Pubitemid 29220739)
-
(1999)
Journal of Neuropathology and Experimental Neurology
, vol.58
, Issue.5
, pp. 459-471
-
-
Martin, L.J.1
-
87
-
-
0033934734
-
Mitochondria and pathogenesis of ALS
-
10869044
-
MF Beal 2000 Mitochondria and pathogenesis of ALS Brain 123 1291 1292 10869044
-
(2000)
Brain
, vol.123
, pp. 1291-1292
-
-
Beal, M.F.1
-
88
-
-
0033917463
-
Mitochondrial DNA abnormalities in skeletal muscle of patients with sporadic amyotrophic lateral sclerosis
-
S Vielhaber D Kunz K Winkler, et al. 2000 Mitochondrial DNA abnormalities in skeletal muscle of patients with sporadic amyotrophic lateral sclerosis Brain 123 1339 1348 10869047 (Pubitemid 30420935)
-
(2000)
Brain
, vol.123
, Issue.7
, pp. 1339-1348
-
-
Vielhaber, S.1
Kunz, D.2
Winkler, K.3
Wiedemann, F.R.4
Kirches, E.5
Feistner, H.6
Heinze, H.-J.7
Elger, C.E.8
Schubert, W.9
Kunz, W.S.10
-
89
-
-
0021816196
-
Functional and morphometric study of the liver in motor neuron disease
-
DOI 10.1007/BF00314034
-
Y Masui T Mozai K Kakehi 1985 Functional and morphometric study of the liver in motor neuron disease J. Neurol. 232 15 19 3998769 1:STN:280: DyaL2M3gvF2mtQ%3D%3D (Pubitemid 15076981)
-
(1985)
Journal of Neurology
, vol.232
, Issue.1
, pp. 15-19
-
-
Masui, Y.1
Mozai, T.2
Kakehi, K.3
-
90
-
-
0031716355
-
Mitochondria in sporadic amyotrophic lateral sclerosis
-
DOI 10.1006/exnr.1998.6866
-
RH Swerdlow JK Parks DS Cassarino, et al. 1998 Mitochondria in sporadic amyotrophic lateral sclerosis Exp. Neurol. 153 135 142 9743575 1:CAS:528:DyaK1cXmvVWgtrw%3D (Pubitemid 28452305)
-
(1998)
Experimental Neurology
, vol.153
, Issue.1
, pp. 135-142
-
-
Swerdlow, R.H.1
Parks, J.K.2
Cassarino, D.S.3
Trimmer, P.A.4
Miller, S.W.5
Maguire, D.J.6
Sheehan, J.P.7
Maguire, R.S.8
Pattee, G.9
Juel, V.C.10
Phillips, L.H.11
Tuttle, J.B.12
Bennett Jr., J.P.13
Davis, R.E.14
Parker Jr., W.D.15
-
92
-
-
84875365596
-
The use of idebenone for correction of mitochondrial pathology in Friedreich's disease
-
MV Ershova SN Illarioshkin 2007 The use of idebenone for correction of mitochondrial pathology in Friedreich's disease Cons. Med. 9 107
-
(2007)
Cons. Med.
, vol.9
, pp. 107
-
-
Ershova, M.V.1
Illarioshkin, S.N.2
-
93
-
-
84860228961
-
Is Friedreich's ataxia an epigenetic disorder?
-
doi: 10.1187/1868-7083-4-2
-
D. Kumari and K. Usdin, "Is Friedreich's ataxia an epigenetic disorder?" Clin. Epigenet., 4, No. 2, doi: 10.1187/1868-7083-4-2 (2012).
-
(2012)
Clin. Epigenet.
, vol.4
, Issue.2
-
-
Kumari, D.1
Usdin, K.2
-
94
-
-
0342700237
-
Recent advances in the molecular pathogenesis of Friedreich ataxia
-
H Puccio M Koenig 2000 Recent advances in the molecular pathogenesis of Friedreich's ataxia Human Mol. Genet. 9 887 892 1:CAS:528:DC%2BD3cXivFyksbk%3D (Pubitemid 30216099)
-
(2000)
Human Molecular Genetics
, vol.9
, Issue.6
, pp. 887-892
-
-
Puccio, H.1
Koenig, M.2
-
95
-
-
13344270899
-
Friedreich's ataxia: Autosomal recessive disease caused by an intronic GAA triplet repeat expansion
-
V Campuzano L Montermini MD Molto, et al. 1996 Friedreich's ataxia: autosomal recessive disease caused by an intronic GAA triplet repeat explanation Science 271 1423 1427 8596916 1:CAS:528:DyaK28XhsFegtbk%3D (Pubitemid 26089479)
-
(1996)
Science
, vol.271
, Issue.5254
, pp. 1423-1427
-
-
Campuzano, V.1
Montermini, L.2
Molto, M.D.3
Pianese, L.4
Cossee, M.5
Cavalcanti, F.6
Monros, E.7
Rodius, F.8
Duclos, F.9
Monticelli, A.10
Zara, F.11
Canizares, J.12
Koutnikova, H.13
Bidichandani, S.I.14
Gellera, C.15
Brice, A.16
Trouillas, P.17
De Michele, G.18
Filla, A.19
De Frutos, R.20
Palau, F.21
Patel, P.I.22
Di Donato, S.23
Mandel, J.-L.24
Cocozza, S.25
Koenig, M.26
Pandolfo, M.27
more..
-
96
-
-
0035380105
-
Friedreich's ataxia and frataxin: Molecular genetics, evolution and pathogenesis
-
11351269 1:CAS:528:DC%2BD3MXktleqsbo%3D
-
F Palau 2001 Friedreich's ataxia and frataxin: molecular genetics, evolution and pathogenesis Int. J. Mol. Med. 7 581 589 11351269 1:CAS:528:DC%2BD3MXktleqsbo%3D
-
(2001)
Int. J. Mol. Med.
, vol.7
, pp. 581-589
-
-
Palau, F.1
-
97
-
-
9844222853
-
Frataxin is reduced in Friedreich ataxia patients and is associated with mitochondrial membranes
-
DOI 10.1093/hmg/6.11.1771
-
V Campuzano L Montermine Y Lutz, et al. 1997 Frataxin is reduced in Friedreich's ataxia patients and is associated with mitochondrial membranes Human Mol. Genet. 6 1771 1780 1:CAS:528:DyaK2sXmslGlt7w%3D (Pubitemid 27460350)
-
(1997)
Human Molecular Genetics
, vol.6
, Issue.11
, pp. 1771-1780
-
-
Campuzano, V.1
Montermini, L.2
Lutz, Y.3
Cova, L.4
Hindelang, C.5
Jiralerspong, S.6
Trottier, Y.7
Kish, S.J.8
Faucheux, B.9
Trouillas, P.10
Authier, F.J.11
Durr, A.12
Mandel, J.-L.13
Vescovi, A.14
Pandolfo, M.15
Koenig, M.16
-
98
-
-
0031253821
-
Aconitase and mitochondrial iron-sulfur protein deficiency in Friedreich's ataxia
-
9326946 1:CAS:528:DyaK2sXmsFantLk%3D
-
A Rotig P de Lonlay D Chretien, et al. 1997 Aconitase and mitochondrial iron-sulfur protein deficiency in Friedreich's ataxia Nat. Genet. 17 215 217 9326946 1:CAS:528:DyaK2sXmsFantLk%3D
-
(1997)
Nat. Genet.
, vol.17
, pp. 215-217
-
-
Rotig, A.1
De Lonlay, P.2
Chretien, D.3
-
99
-
-
0030813487
-
Studies of human, mouse and yeast homologues indicate a mitochondrial function for frataxin
-
DOI 10.1038/ng0897-345
-
H Koutnikova V Campuzano F Foury, et al. 1997 Studies of human, mouse and yeast homologues indicate a mitochondrial function of frataxin Nat. Genet. 16 345 351 9241270 1:CAS:528:DyaK2sXkvFChtr4%3D (Pubitemid 27323298)
-
(1997)
Nature Genetics
, vol.16
, Issue.4
, pp. 345-351
-
-
Koutnikova, H.1
Campuzano, V.2
Foury, F.3
Dolle, P.4
Cazzalini, O.5
Koenig, M.6
-
100
-
-
84856687068
-
Oxidative stress induces mitochondrial fragmentation in frataxin-deficient cells
-
1:CAS:528:DC%2BC38Xhs1Ggsro%3D
-
S Lefevre D Sliwa P Rustin, et al. 2012 Oxidative stress induces mitochondrial fragmentation in frataxin-deficient cells Biochem. Biophys. Commun. 418 336 341 1:CAS:528:DC%2BC38Xhs1Ggsro%3D
-
(2012)
Biochem. Biophys. Commun.
, vol.418
, pp. 336-341
-
-
Lefevre, S.1
Sliwa, D.2
Rustin, P.3
-
101
-
-
0033957174
-
Clinical, biochemical and molecular genetic correlations in Friedreich's ataxia
-
JL Bradley JC Blake S Chamberlain, et al. 2000 Clinical, biochemical and molecular genetic correlations in Friedreich's ataxia Human Mol. Genet. 9 275 282 1:CAS:528:DC%2BD3cXhtVaksLg%3D (Pubitemid 30052751)
-
(2000)
Human Molecular Genetics
, vol.9
, Issue.2
, pp. 275-282
-
-
Bradley, J.L.1
Blake, J.C.2
Chamberlain, S.3
Thomas, P.K.4
Cooper, J.M.5
Schapira, A.H.V.6
-
102
-
-
0032471513
-
Getting to the nucleus of mitochondrial disorders: Identification of respiratory chain-enzymes genes causing Leigh syndrome
-
1:CAS:528:DyaK1MXltF2ruw%3D%3D
-
H-HM Dahl 1998 Getting to the nucleus of mitochondrial disorders: identification of respiratory chain-enzymes genes causing Leigh syndrome Am. J. Human Genet. 63 1594 1597 1:CAS:528:DyaK1MXltF2ruw%3D%3D
-
(1998)
Am. J. Human Genet.
, vol.63
, pp. 1594-1597
-
-
H-Hm, D.1
-
103
-
-
2442706495
-
Late-onset Leigh syndrome in a patient with mitochondrial complex I NDUFS8 mutations
-
V Procaccio DC Wallace 2004 Late-onset Leigh syndrome in patients with mitochondrial complex I NDUFS8 mutations Neurology 62 1899 1901 15159508 (Pubitemid 38661765)
-
(2004)
Neurology
, vol.62
, Issue.10
, pp. 1899-1901
-
-
Procaccio, V.1
Wallace, D.C.2
-
104
-
-
0029985716
-
Leigh syndrome: Clinical features and biochemical and DNA abnormalities
-
DOI 10.1002/ana.410390311
-
S Rahman RB Block HH Dahl, et al. 1996 Leigh syndrome: clinical features and biochemical and DNA abnormalities Ann. Neurol. 39 343 351 8602753 1:CAS:528:DyaK28XisFyrsbw%3D (Pubitemid 26100758)
-
(1996)
Annals of Neurology
, vol.39
, Issue.3
, pp. 343-351
-
-
Rahman, S.1
Blok, R.B.2
Dahl, H.-H.M.3
Danks, D.M.4
Kirby, D.M.5
Chow, C.W.6
Christodoulou, J.7
Thorburn, D.R.8
-
105
-
-
0029891215
-
Genetic heterogeneity in Leigh syndrome
-
8687192 1:STN:280:DyaK283psF2gsw%3D%3D
-
S DiMauro DC De Vivo 1996 Genetic heterogeneity in Leigh syndrome Ann. Neurol. 40 5 7 8687192 1:STN:280:DyaK283psF2gsw%3D%3D
-
(1996)
Ann. Neurol.
, vol.40
, pp. 5-7
-
-
Dimauro, S.1
De Vivo, D.C.2
-
106
-
-
0032470811
-
Mutations of SURF-1 in Leigh disease associated with cytochrome C oxidase deficiency
-
DOI 10.1086/302150
-
V Tiranti K Hoertnagel R Carrozzo, et al. 1998 Mutations of SURF-1 in Leigh disease associated with cytochrome c oxidase deficiency Am. J. Human Genet. 63 1609 1621 1:CAS:528:DyaK1MXltF2qsw%3D%3D (Pubitemid 30415723)
-
(1998)
American Journal of Human Genetics
, vol.63
, Issue.6
, pp. 1609-1621
-
-
Tiranti, V.1
Hoertnagel, K.2
Carrozzo, R.3
Calimberti, C.4
Munaro, M.5
Granatiero, M.6
Zelante, L.7
Gasparini, P.8
Marzella, R.9
Rocchi, M.10
Pilar Bayona-Bafaluy, M.11
Enriquez, J.-A.12
Uziel, G.13
Bertini, E.14
Dionisi-Vici, C.15
Franco, B.16
Meitinger, T.17
Zeviani, M.18
-
107
-
-
0032471351
-
The first nuclear-encoded complex I mutation in a patient with Leigh syndrome
-
DOI 10.1086/302154
-
J Loeffen J Smeitink R Triepels, et al. 1998 The first nuclear-encoded complex I mutation in a patient with Leigh syndrome Am. J. Human Genet. 63 1598 1608 1:CAS:528:DyaK1MXltF2qsg%3D%3D (Pubitemid 30415722)
-
(1998)
American Journal of Human Genetics
, vol.63
, Issue.6
, pp. 1598-1608
-
-
Loeffen, J.1
Smeitink, J.A.M.2
Triepels, R.3
Smeets, R.4
Schuelke, M.5
Sengers, R.6
Trijbels, F.7
Hamel, B.8
Mullaart, R.9
Van Heuvel, L.D.10
-
108
-
-
77957657807
-
The p.M292T NDUFS2 mutation causes complex I-deficient Leigh syndrome in multiple families
-
20819849
-
HA Tuppen VE Hogan L He, et al. 2010 The p.M292T NDUFS2 mutation causes complex I-deficient Leigh syndrome in multiple families Brain 133 2952 2963 20819849
-
(2010)
Brain
, vol.133
, pp. 2952-2963
-
-
Tuppen, H.A.1
Hogan, V.E.2
He, L.3
-
109
-
-
81055158015
-
Respiratory chain complex i deficiency due to NDUFA12 mutations as a new cause of Leigh syndrome
-
E Ostergaard RJ Rodenburg M van der Brand, et al. 2012 Respiratory chain complex I deficiency due to NDUFA12 mutations as a new cause of Leigh syndrome J. Med. Genet. 48 737 740
-
(2012)
J. Med. Genet.
, vol.48
, pp. 737-740
-
-
Ostergaard, E.1
Rodenburg, R.J.2
Van Der Brand, M.3
-
110
-
-
60349108806
-
Mitochondrial medicine for aging and neurodegenerative diseases
-
1:CAS:528:DC%2BD1MXhtlKktQ%3D%3D
-
PH Reddy 2008 Mitochondrial medicine for aging and neurodegenerative diseases Neuromol. Med. 10 291 315 1:CAS:528:DC%2BD1MXhtlKktQ%3D%3D
-
(2008)
Neuromol. Med.
, vol.10
, pp. 291-315
-
-
Reddy, P.H.1
|