Mitochondria in sporadic amyotrophic lateral sclerosis

Experimental Neurology

Volumn 153, Issue 1, 1998, Pages 135-142

  Swerdlow, Russell H ^a   Parks, Janice K ^a   Cassarino, David S ^a   Trimmer, Patricia A ^a   Miller, Scott W ^b   Maguire, David J ^c   Sheehan, Jason P ^a   Maguire, Robyn S ^a   Pattee, Gary ^d   Juel, Vern C ^a   Phillips, Lawrence H ^a   Tuttle, Jeremy B ^a   Bennett Jr , James P ^a   Davis, Robert E ^b   Parker Jr , W Davis ^a  

^a UNIVERSITY OF VIRGINIA HEALTH SYSTEM   (United States)

^b Migenix Inc   (United States)

^c GRIFFITH UNIVERSITY   (Australia)

^d NONE

Author keywords

ALS; Amyotrophic lateral sclerosis; Calcium; Cybrids; DNA; Mitochondria; Oxidative

Indexed keywords

MITOCHONDRIAL DNA;

AMYOTROPHIC LATERAL SCLEROSIS; ANTIOXIDANT ACTIVITY; ARTICLE; CALCIUM BALANCE; CLINICAL ARTICLE; CONTROLLED STUDY; ELECTRON TRANSPORT; ENZYME ACTIVITY; FEMALE; HUMAN; HUMAN CELL; MALE; MITOCHONDRIAL RESPIRATION; OXIDATIVE STRESS; PATHOPHYSIOLOGY; PRIORITY JOURNAL; RESPIRATORY CHAIN;

EID: 0031716355     PISSN: 00144886     EISSN: None     Source Type: Journal    
DOI: 10.1006/exnr.1998.6866     Document Type: Article

References (45)

1. Balazs, L., and M. Leon. 1994. Evidence of an oxidative challenge in the Alzheimer's brain. Neurochem. Res. 19: 1131-1137.
2. Bowling, A. C., J. B. Schulz, R. H. Brown Jr, and M. F. Beal. 1993. Superoxide dismutase activity, oxidative damage, and mitochondrial energy metabolism in familial and sporadic amyotrophic lateral sclerosis. J. Neurochem. 61: 2322-2325.
3. Cassarino, D. S., C. P. Fall, R. H. Swerdlow, T. S. Smith, E. M. Halvorsen, S. W. Miller, J. K. Parks, W. D. Parker, and J. P. Bennett Jr. 1997. Elevated reactive oxygen species and antioxidant enzyme activities in animal and cellular models of Parkinson's disease. Biochim. Biophys. Acta. 1362: 77-86.
4. Ceballos-Picot, I., M. Merad-Boudia, A. Nicole, M. Thevenisn, G. Hellier, S. Legrain, and C. Berr. 1996. Peripheral anti-oxidant enzyme activities and selenium in elderly subjects and in dementia of Alzheimer's type - Place of the extracellular glutathione peroxidase. Free Rad. Biol. Med. 20: 579-587.
5. lys mutation causing myoclonic epilepsy and ragged red fibers. J. Hum. Genet. 54: 966-974.
6. Chou, S. M., H. S. Wang, and A. Taniguchi. 1996. Role of SOD-1 and nitric oxide/cyclic GMP cascade on neurofilament aggregation in ALS/MND. J. Neurol. Sci. 139 (suppl): 16-26.
7. Curti, D., A. Malaspina, G. Facchetti, C. Camana, L. Mazzini, P. Tosca, F. Zerbi, and M. Ceroni. 1996. Amyotrophic lateral sclerosis: Oxidative energy metabolism and calcium homeostasis in peripheral blood lymphocytes. Neurology 47: 1060-1064.
8. Dal Canto, M. C., and M. E. Gurney. 1994. Development of central nervous system pathology in a murine transgenic model of human amyotrophic lateral sclerosis. Am. J. Path. 145: 1271-1279.
9. Dal Canto, M. C., and M. E. Gurney. 1997. Alow expressor line of transgenic mice carrying a mutant human Cu, Zn superoxide dismutase (SOD1) gene develops pathological changes that most closely resemble those in human amyotrophic lateral sclerosis. Acta Neuropathol. 93: 537-550.
10. Damier, P., E. C. Hirsch, P. Zhang, Y. Agid, and F. Javoy-Agid. 1993. Glutathione peroxidase, glial cells and Parkinson's disease. Neuroscience 52: 1-6.
11. de Lustig, E. S., J. A. Serra, S. Kohan, G. A. Canziani, A. L. Famulari, and R. O. Dominguez. 1993. Copper-zinc superoxide dismutase activity in red blood cells and serum in demented patients and in aging. J. Neurol. Sci. 115: 18-25.
12. Elizan, T. S., A. Hirano, B. M. Abrams, R. L. Need, C. Van Nuis, and L. T. Kurland. 1966. Amyotrophic lateral sclerosis and parkinsonism-dementia on Guam. Neurology 14: 356-368.
13. 2+ accumulation in cortical cell culture correlates with subsequent neuronal degeneration. J. Neurosci. 13: 1993-2000.
14. Hirano, A., I. Nakano, L. T. Kurland, D. W. Mulder, P. W. Holley, and G. Saccomanno. 1984. Fine structural study of neurofibrillary changes in a family with amyotrophic lateral sclerosis. J. Neuropath. Exp. Neurol. 43: 471-480.
15. Hirano, A., H. Donnenfeld, S. Sasaki, and I. Nakano. 1984. Fine structural observations of neurofilamentous changes in amyotrophic lateral sclerosis. J. Neuropath. Exp. Neurol. 43: 461-470.
16. Hirano, A. 1991. Cytopathology of Amyotrophic Lateral Sclerosis. In: Rowland L. P., ed. Advances in Neurology, Vol 56: Amyotrophic Lateral Sclerosis and Other Motor Neuron Diseases. Raven Press, New York, 1991: 91-101.
17. Kalra, J., A. H. Rajput, S. V. Mantha, and K Prasad. 1992. Serum antioxidant enzyme activity in Parkinson's disease. Mol. Cell. Biochem. 110: 165-168.
18. Kasarskis, E. J., L. Tandon, M. A. Lovell, and W. D. Ehmann. 1995. Aluminum, calcium, and iron in the spinal cord of patients with sporadic amyotrophic lateral sclerosis using laser microprobe mass spectroscopy: A preliminary study. J. Neurol. Sci. 130: 203-208.
19. King, M. P., and G. Attardi. Human cells lacking mtDNA: Repopulation with exogenous mitochondria by complementation. Science 246: 500-503.
20. Law, P. K., A. Saito, and S. Fleischer. 1983. Study of neurotrophin in normal/dystrophic parabiotic mice. Exp. Neurol. 80: 761-782.
21. Leone, M. 1991. Parental sex effect in familial amyotrophic lateral sclerosis. Neurology 41: 1292-1294.
22. Majoor-Krakauer, D., R. Ottman, W. G. Johnson, and L. P. Rowland. 1994. Familial aggregation of amyotrophic lateral sclerosis, dementia, and Parkinson's disease: Evidence of shared genetic susceptibility. Neurology 44: 1872-1877.
23. Martilla, R. J., H. Lorentz, and U. K Rinne. 1988. Oxygen toxicity protecting enzymes in Parkinson's disease. Increase of superoxide dismutase-like activity in the substantia nigra and basal nucleus. J. Neurol. Sci. 86: 321-331.
24. Miller, S. W., P. A. Trimmer, W. D. Parker Jr., and R. E. Davis. 1996. Creation and characterization of mitochondrial DNA depleted cell lines with "neuronal-like" properties. J. Neurochem. 67: 1897-1907.
25. Mizuno, Y., S. Ohta, M. Tanaka, S. Takamiya, K. Suzuki, T. Sato, H. Oya, T. Ozawa, and Y Kagawa. 1989. Deficiencies in complex I subunits of the respiratory chain in Parkinson's disease. Biochem. Biophys. Res. Commun. 163: 1450-1455.
26. Nakano, K., K. Hirayama, and K. Terao. 1987. Hepatic ultrastructural changes and liver dysfunction in amyotrophic lateral sclerosis. Arch. Neurol. 44: 103-106.
27. Nicotera, P., and S. Orrenius. 1992. Calcium and cell death. Ann. N.Y. Acad. Sci. 648: 17-27.
28. Okamoto, K., S. Hirai, M. Shoji, Y. Senoh, and T. Yamazaki. 1990. Axonal swellings in the corticospinal tracts in amyotrophic lateral sclerosis. Acta Neuropath. 80: 222-226.
29. 2+ level. J. Immunol. 154: 599-609.
30. Parker, W. D., S. J. Boyson, and J. K. Parks. 1989. Electron transport chain abnormalities in idiopathic Parkinson's disease. Ann. Neurol. 26: 719-723.
31. Parker, W. D., C. M. Filley, and J. K. Parks. 1990. Cytochrome oxidase deficiency in Alzheimer's disease. Neurology 40: 1302-1303.
32. Parker, W. D. Jr, J. K. Parks, C. M. Filley, and B. K. Kleinschmidt-DeMasters. 1994. Electron transport chain defects in Alzheimer's disease. Neurology 44: 1090-1096.
33. Saggu, H., J. Cooksey, D. Dexter, F. R. Wells, A. Lees, P. Jenner, and C. D. Marsden. 1989. A selective increase in particulate superoxide dismutase activity in parkinsonian substantia nigra. J. Neurochem. 53: 692-697.
34. Schapira, A. H. V., J. M. Cooper, D. Dexter, P. Jenner, J. B. Clark, and C. D. Marsden. 1989. Mitochondrial complex I deficiency in Parkinson's disease. Lancet i: 1289.
35. Shaw, P. J., P. G. Ince, G. Falkaus, and D. Mantle. 1995. Oxidative damage to protein in sporadic motor neuron disease spinal cord. Ann. Neurol. 38: 691-695.
36. Sheehan, J. P., R. H. Swerdlow, S. W. Miller, R. E. Davis, and J. B. Tuttle. 1997. Altered calcium homeostasis and reactive oxygen species production in cells transformed by Alzheimer's disease mitochondrial DNA. J. Neurosci. 17: 4612-4622.
37. Siklos, L., J. Engelhardt, Y. Harati, G. R. Smith, F. Joo, and S. H. Appel. 1996. Ultrastructural evidence for altered calcium in motor nerve terminals in amyotrophic lateral sclerosis. Ann. Neurol. 39: 203-216.
38. Swerdlow, R. H., J. K. Parks, S. W. Miller, J. B. Tuttle, P. A. Trimmer, J. P. Sheehan, J. P. Bennett, R. E. Davis, and W. D. Parker WD Jr. 1996. Origin and functional consequences of the complex I defect in Parkinson's disease. Ann. Neurol. 40: 663-671.
39. Swerdlow, R. H., J. K. Parks, D. S. Cassarino, D. J. Maguire, R. S. Maguire, J. P. Bennett Jr., R. E. Davis, and W. D. Parker Jr. 1997. Cybrids in Alzheimer's disease: A cellular model of the disease? Neurology 49: 918-925.
40. Tong, J. X., M. E. Eichler, and K. M. Rich. 1996. Intracellular calcium levels influence apoptosis in mature sensory neurons after trophic factor deprivation. Exp. Neurol. 138: 45-52.
41. Uitei, K., S. Sato, T. Miyake, and Y. Miyata. 1996. Induction of apoptosis in a drosophila neuronal cell line by calcium ionophore. Neurosci. Lett. 203: 191-194.
42. Witt, M. R., O. Gredal, K. Dekermendjian, M. Unden, and M. Nielsen. 1994. Calcium homeostasis in fibroblasts from patients with amyotrophic lateral sclerosis. J. Neurol. Sci. 126: 206-212.
43. World Federation of Neurology Research Group on Neuromuscular Diseases. 1994. El Escorial World Federation of Neurology criteria for the diagnosis of amyotrophic lateral sclerosis. J. Neurol. Sci. 124(suppl): 96-107.
44. Wong, P. C., C. A. Pardo, D. R. Borchelt, M. K. Lee, N. G. Copeland, N. A. Jenkins, S. S. Sisodia, D. W. Cleveland, and D. L. Price. 1995. An adverse property of familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria. Neuron 14: 1105-1116.
45. Zemlan, F., O. J. Thienhaus, and H. B. Bosmann. 1989. Superoxide dismutase activity in Alzheimer's disease mechanism for paired helical filament formation. Brain. Res. 476: 160-162.