Sequence determinants of enhanced amyloidogenicity of Alzheimer Aβ42 peptide relative to Aβ40

Journal of Biological Chemistry

Volumn 280, Issue 41, 2005, Pages 35069-35076

  Kim, Woojin ^a   Hecht, Michael H ^a  

^a PRINCETON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AGGLOMERATION; CORRELATION METHODS; DISEASE CONTROL; FLUORESCENCE; HYDROPHILICITY; PATHOLOGY;

GREEN FLUORESCENCE PROTEIN (GFP); MUTANTS; PEPTIDES; SEQUENCE DETERMINANTS;

PROTEINS;

ALANINE; AMYLOID BETA PROTEIN[1-40]; AMYLOID BETA PROTEIN[1-42]; GREEN FLUORESCENT PROTEIN; HYBRID PROTEIN; ISOLEUCINE; MUTANT PROTEIN;

ALZHEIMER DISEASE; ARTICLE; BETA SHEET; FLUORESCENCE; HIGH THROUGHPUT SCREENING; HYDROPHILICITY; HYDROPHOBICITY; MUTATION; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN FOLDING; SENILE PLAQUE; SEQUENCE ANALYSIS;

ALZHEIMER DISEASE; AMYLOID; AMYLOID BETA-PROTEIN; BIOPHYSICS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DNA PRIMERS; GREEN FLUORESCENT PROTEINS; HUMANS; KINETICS; MICROSCOPY, FLUORESCENCE; MODELS, CHEMICAL; MUTATION; PEPTIDE FRAGMENTS; PEPTIDE LIBRARY; PEPTIDES; PHENOTYPE; PROTEIN STRUCTURE, SECONDARY; RECOMBINANT FUSION PROTEINS; SEQUENCE ANALYSIS, PROTEIN; TEMPERATURE; THIAZOLES; TIME FACTORS;

EID: 27144447811     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M505763200     Document Type: Article

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