Caveolin-1 is essential for liver regeneration

Science

Volumn 313, Issue 5793, 2006, Pages 1628-1632

  Fernàndez, Manuel A ^a,b   Albor, Cecilia ^a   Ingelmo Torres, Mercedes ^a   Nixon, Susan J ^b   Ferguson, Charles ^b   Kurzchalia, Teymuras ^c   Tebar, Francesc ^a   Enrich, Carlos ^a   Parton, Robert G ^b   Pol, Albert ^a  

^a UNIVERSITY OF BARCELONA   (Spain)

^b UNIVERSITY OF QUEENSLAND   (Australia)

^c MAX PLANCK INSTITUTE OF MOLECULAR CELL BIOLOGY AND GENETICS   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL ORGANS; CELLS; ENZYMES; GLUCOSE; LIPIDS; METABOLISM;

CAVEOLIN-1; CELLULAR INJURIES; HEPATECTOMY; HEPATOCYTES;

BIOCHEMICAL ENGINEERING;

CAVEOLIN; GLUCOSE;

GENE EXPRESSION; LIPID; METABOLISM; REGENERATION; RODENT; SURVIVAL;

ARTICLE; CAVEOLIN 1 GENE; CELL ACTIVATION; CELL CYCLE; CELL DAMAGE; CELL DIVISION; CELL PROLIFERATION; GENE; GENE DISRUPTION; LIPID METABOLISM; LIVER CELL; LIVER REGENERATION; MOUSE; NONHUMAN; PARTIAL HEPATECTOMY; PRIORITY JOURNAL; SURVIVAL;

ANIMALS; CAVEOLAE; CAVEOLIN 1; CELL CYCLE; CELL DIVISION; FATTY ACIDS; GLUCOSE; HEPATECTOMY; HEPATOCYTE GROWTH FACTOR; HEPATOCYTES; LIPID METABOLISM; LIPIDS; LIVER; LIVER REGENERATION; MALE; MICE; PHOSPHORYLATION; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR; TRIGLYCERIDES;

EID: 33748773325     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1130773     Document Type: Article

References (17)

1. N. Fausto, Hepatology 39, 1477 (2004).
2. G. K. Michatopoutos, W. C. DeFrances, Science 276, 60 (1997).
3. R. Taub, Nat. Rev. Mol. Cell Biol. 5, 836 (2004).
4. E. A. Glende Jr., W. S. Morgan, Exp. Mol. Pathol. 8, 190 (1968).
5. G. C. Farrell, Hepatology 40, 1252 (2004).
6. T. V. Kurzchalia, R. G. Parton, Curr. Opin. Cell Biol. 11, 424 (1999).
7. A. Pol et al., J. Cell Biol. 152, 1057 (2001).
8. 8: A. Pol et al., Mol. Biol. Cell 15, 99 (2004).
9. M. Drab et al., Science 293, 2449 (2001).
10. S. Le Lay, T. V. Kurzchalia, Biochim Biophys Acta 1746, 322 (2005).
11. J. H. Albrecht et al., Oncogene 16, 2141 (1998).
12. H. S. Lai, W. J. Chen, K. M. Chen, J. Parenter. Enteral Nutr. 16, 152 (1992).
13. J. Simek, V. Chmelar, J. Melka, Z. Pazderka, Z. Charvat, Nature 213, 910 (1967).
14. N. L. R. Bucher, R. A. Malt, Regeneration of Liver and Kidney (Little, Brown, Boston, 1971).
15. J. A. Caruana, D. A. Whalen Jr., W. P. Anthony, C. R. Sunby, M. P. Ciechoski, Endocr. Kes. 12, 147 (1986).
16. M. Holecek, J. Simek, Exp. Pathol. 33, 257 (1988).
17. We thank A. Giménez, C. Claries, and O. Collazo from the Animal Facility (University of Barcelona) and the CORE facility (Hospital Clinic i Provincial de Barcelona). This work was supported by grants BMC2003-04754 and GEN2003-20662 to C.E. and BFU2005-01716 and GEN2003-20662 to A.P. [Ministerio de Education y Ciencia (MEC), Spain] and a program grant from the National Health and Medical Research Council of Australia to R.G.P. A.P. and F.T. are supported by Ramon y Cajal Research Program (MEC). M.A.F. is supported by the postdoctoral fellowship program EX2005-0850 (MEC).