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Volumn 168, Issue 6, 2006, Pages 1998-2013

Caveolin-1 mutations in human breast cancer: Functional association with estrogen receptor α-positive status

Author keywords

[No Author keywords available]

Indexed keywords

CAVEOLIN 1; CYCLIN D1; ESTROGEN RECEPTOR ALPHA; GENOMIC DNA;

EID: 33744776333     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: 10.2353/ajpath.2006.051089     Document Type: Article
Times cited : (97)

References (55)
  • 1
    • 13644266312 scopus 로고    scopus 로고
    • Caveolin-1 in oncogenic transformation, cancer, and metastasis
    • Williams TM, Lisanti MP: Caveolin-1 in oncogenic transformation, cancer, and metastasis. Am J Physiol Cell Physiol 2005, 288:C494-C506
    • (2005) Am J Physiol Cell Physiol , vol.288
    • Williams, T.M.1    Lisanti, M.P.2
  • 3
    • 0028953271 scopus 로고
    • Reduction of caveolin and caveolae in oncogenically transformed cells
    • Koleske AJ, Baltimore D, Lisanti MP: Reduction of caveolin and caveolae in oncogenically transformed cells. Proc Natl Acad Sci USA 1995, 92:1381-1385
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 1381-1385
    • Koleske, A.J.1    Baltimore, D.2    Lisanti, M.P.3
  • 5
    • 0032546319 scopus 로고    scopus 로고
    • Tumor cell growth inhibition by caveolin re-expression in human breast cancer cells
    • Lee SW, Reimer CL, Oh P, Campbell DB, Schnitzer JE: Tumor cell growth inhibition by caveolin re-expression in human breast cancer cells. Oncogene 1998, 16:1391-1397
    • (1998) Oncogene , vol.16 , pp. 1391-1397
    • Lee, S.W.1    Reimer, C.L.2    Oh, P.3    Campbell, D.B.4    Schnitzer, J.E.5
  • 7
    • 0037018405 scopus 로고    scopus 로고
    • Caveolin-1 inhibits anchorage-independent growth, anoikis and invasiveness in MCF-7 human breast cancer cells
    • Fiucci G, Ravid D, Reich R, Liscovitch M: Caveolin-1 inhibits anchorage-independent growth, anoikis and invasiveness in MCF-7 human breast cancer cells. Oncogene 2002, 21:2365-2375
    • (2002) Oncogene , vol.21 , pp. 2365-2375
    • Fiucci, G.1    Ravid, D.2    Reich, R.3    Liscovitch, M.4
  • 8
    • 0034617296 scopus 로고    scopus 로고
    • Caveolin-1 inhibits epidermal growth factor-stimulated lamellipod extension and cell migration in metastatic mammary adenocarcinoma cells (MTLn3). Transformation suppressor effects of adenovirus-mediated gene delivery of caveolin-1
    • Zhang W, Razani B, Altschuler Y, Bouzahzah B, Mostov KE, Pestell RG, Lisanti MP: Caveolin-1 inhibits epidermal growth factor-stimulated lamellipod extension and cell migration in metastatic mammary adenocarcinoma cells (MTLn3). Transformation suppressor effects of adenovirus-mediated gene delivery of caveolin-1. J Biol Chem 2000, 275:20717-20725
    • (2000) J Biol Chem , vol.275 , pp. 20717-20725
    • Zhang, W.1    Razani, B.2    Altschuler, Y.3    Bouzahzah, B.4    Mostov, K.E.5    Pestell, R.G.6    Lisanti, M.P.7
  • 9
    • 7644227012 scopus 로고    scopus 로고
    • Caveolin-1 inhibits breast cancer growth and metastasis
    • Sloan EK, Stanley KL, Anderson RL: Caveolin-1 inhibits breast cancer growth and metastasis. Oncogene 2004, 23:7893-7897
    • (2004) Oncogene , vol.23 , pp. 7893-7897
    • Sloan, E.K.1    Stanley, K.L.2    Anderson, R.L.3
  • 10
    • 0036791604 scopus 로고    scopus 로고
    • Caveolin-1 mutations (P132L and null) and the pathogenesis of breast cancer: Caveolin-1 (P132L) behaves in a dominant-negative manner and caveolin-1 (-/-) null mice show mammary epithelial cell hyperplasia
    • Lee H, Park DS, Razani B, Russell RG, Pestell RG, Lisanti MP: Caveolin-1 mutations (P132L and null) and the pathogenesis of breast cancer: Caveolin-1 (P132L) behaves in a dominant-negative manner and caveolin-1 (-/-) null mice show mammary epithelial cell hyperplasia. Am J Pathol 2002, 161:1357-1369
    • (2002) Am J Pathol , vol.161 , pp. 1357-1369
    • Lee, H.1    Park, D.S.2    Razani, B.3    Russell, R.G.4    Pestell, R.G.5    Lisanti, M.P.6
  • 11
    • 2642549186 scopus 로고    scopus 로고
    • Combined loss of INK4a and caveolin-1 synergistically enhances cell proliferation and oncogene-induced tumorigenesis: Role of INK4a/CAV-1 in mammary epithelial cell hyperplasia
    • Williams TM, Lee H, Cheung MW, Cohen AW, Razani B, Iyengar P, Scherer PE, Pestell RG, Lisanti MP: Combined loss of INK4a and caveolin-1 synergistically enhances cell proliferation and oncogene-induced tumorigenesis: Role of INK4a/CAV-1 in mammary epithelial cell hyperplasia. J Biol Chem 2004, 279:24745-24756
    • (2004) J Biol Chem , vol.279 , pp. 24745-24756
    • Williams, T.M.1    Lee, H.2    Cheung, M.W.3    Cohen, A.W.4    Razani, B.5    Iyengar, P.6    Scherer, P.E.7    Pestell, R.G.8    Lisanti, M.P.9
  • 13
    • 19944366937 scopus 로고    scopus 로고
    • Caveolin-1 gene disruption promotes mammary tumorigenesis and dramatically enhances lung metastasis in vivo. Role of Cav-1 in cell invasiveness and matrix metalloproteinase (MMP-2/9) secretion
    • Williams TM, Medina F, Badano I, Hazan RB, Hutchinson J, Muller WJ, Chopra NG, Scherer PE, Pestell RG, Lisanti MP: Caveolin-1 gene disruption promotes mammary tumorigenesis and dramatically enhances lung metastasis in vivo. Role of Cav-1 in cell invasiveness and matrix metalloproteinase (MMP-2/9) secretion. J Biol Chem 2004, 279:51630-51646
    • (2004) J Biol Chem , vol.279 , pp. 51630-51646
    • Williams, T.M.1    Medina, F.2    Badano, I.3    Hazan, R.B.4    Hutchinson, J.5    Muller, W.J.6    Chopra, N.G.7    Scherer, P.E.8    Pestell, R.G.9    Lisanti, M.P.10
  • 14
    • 0031758918 scopus 로고    scopus 로고
    • Genes encoding human caveolin-1 and -2 are co-localized to the D7S522 locus (7q31.1), a known fragile site (FRA7G) that is frequently deleted in human cancers
    • Engelman JA, Zhang XL, Lisanti MP: Genes encoding human caveolin-1 and -2 are co-localized to the D7S522 locus (7q31.1), a known fragile site (FRA7G) that is frequently deleted in human cancers. FEBS Lett 1998, 436:403-410
    • (1998) FEBS Lett , vol.436 , pp. 403-410
    • Engelman, J.A.1    Zhang, X.L.2    Lisanti, M.P.3
  • 15
    • 0028091664 scopus 로고
    • (C-A)n microsatellite repeat D7S522 is the most commonly deleted region in human primary breast cancer
    • Zenklusen JC, Bieche I, Lidereau R, Conti CJ: (C-A)n microsatellite repeat D7S522 is the most commonly deleted region in human primary breast cancer. Proc Natl Acad Sci USA 1994, 91:12155-12158
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 12155-12158
    • Zenklusen, J.C.1    Bieche, I.2    Lidereau, R.3    Conti, C.J.4
  • 16
    • 0028641304 scopus 로고
    • Loss of heterozygosity in human primary prostate carcinomas: A possible tumor suppressor gene at 7q31.1
    • Zenklusen JC, Thompson JC, Troncoso P, Kagan J, Conti CJ: Loss of heterozygosity in human primary prostate carcinomas: a possible tumor suppressor gene at 7q31.1. Cancer Res 1994, 54:6370-6373
    • (1994) Cancer Res , vol.54 , pp. 6370-6373
    • Zenklusen, J.C.1    Thompson, J.C.2    Troncoso, P.3    Kagan, J.4    Conti, C.J.5
  • 17
    • 0028929987 scopus 로고
    • Frequent loss of heterozygosity in human primary squamous cell and colon carcinomas at 7q31.1: Evidence for a broad range tumor suppressor gene
    • Zenklusen JC, Thompson JC, Klein-Szanto AJ, Conti CJ: Frequent loss of heterozygosity in human primary squamous cell and colon carcinomas at 7q31.1: evidence for a broad range tumor suppressor gene. Cancer Res 1995, 55:1347-1350
    • (1995) Cancer Res , vol.55 , pp. 1347-1350
    • Zenklusen, J.C.1    Thompson, J.C.2    Klein-Szanto, A.J.3    Conti, C.J.4
  • 18
    • 0029121078 scopus 로고
    • Allelic loss at 7q31.1 in human primary ovarian carcinomas suggests the existence of a tumor suppressor gene
    • Zenklusen JC, Weitzel JN, Ball HG, Conti CJ: Allelic loss at 7q31.1 in human primary ovarian carcinomas suggests the existence of a tumor suppressor gene. Oncogene 1995, 11:359-363
    • (1995) Oncogene , vol.11 , pp. 359-363
    • Zenklusen, J.C.1    Weitzel, J.N.2    Ball, H.G.3    Conti, C.J.4
  • 21
    • 0030700907 scopus 로고    scopus 로고
    • Loss of heterozygosity on the long arm of human chromosome 7 in sporadic renal cell carcinomas
    • Shridhar V, Sun QC, Miller OJ, Kalemkerian GP, Petras J, Smith DI: Loss of heterozygosity on the long arm of human chromosome 7 in sporadic renal cell carcinomas. Oncogene 1997, 15:2727-2733
    • (1997) Oncogene , vol.15 , pp. 2727-2733
    • Shridhar, V.1    Sun, Q.C.2    Miller, O.J.3    Kalemkerian, G.P.4    Petras, J.5    Smith, D.I.6
  • 22
    • 0031892622 scopus 로고    scopus 로고
    • Fish mapping of YAC clones at human chromosomal band 7q31.2: Identification of YACS spanning FRA7G within the common region of LOH in breast and prostate cancer
    • Huang H, Qian C, Jenkins RB, Smith DI: Fish mapping of YAC clones at human chromosomal band 7q31.2: identification of YACS spanning FRA7G within the common region of LOH in breast and prostate cancer. Genes Chromosomes Cancer 1998, 21:152-159
    • (1998) Genes Chromosomes Cancer , vol.21 , pp. 152-159
    • Huang, H.1    Qian, C.2    Jenkins, R.B.3    Smith, D.I.4
  • 26
    • 0030670385 scopus 로고    scopus 로고
    • Dissociation between steroid receptor expression and cell proliferation in the human breast
    • Clarke RB, Howell A, Potten CS, Anderson E: Dissociation between steroid receptor expression and cell proliferation in the human breast. Cancer Res 1997, 57:4987-4991
    • (1997) Cancer Res , vol.57 , pp. 4987-4991
    • Clarke, R.B.1    Howell, A.2    Potten, C.S.3    Anderson, E.4
  • 27
    • 0032980947 scopus 로고    scopus 로고
    • Oestrogen receptor expression in the normal and pre-cancerous breast
    • Shoker BS, Jarvis C, Sibson DR, Walker C, Sloane JP: Oestrogen receptor expression in the normal and pre-cancerous breast. J Pathol 1999, 188:237-244
    • (1999) J Pathol , vol.188 , pp. 237-244
    • Shoker, B.S.1    Jarvis, C.2    Sibson, D.R.3    Walker, C.4    Sloane, J.P.5
  • 31
    • 0034839704 scopus 로고    scopus 로고
    • The interplay of matrix metalloproteinases, morphogens and growth factors is necessary for branching of mammary epithelial cells
    • Simian M, Hirai Y, Navre M, Werb Z, Lochter A, Bissell MJ: The interplay of matrix metalloproteinases, morphogens and growth factors is necessary for branching of mammary epithelial cells. Development 2001, 128:3117-3131
    • (2001) Development , vol.128 , pp. 3117-3131
    • Simian, M.1    Hirai, Y.2    Navre, M.3    Werb, Z.4    Lochter, A.5    Bissell, M.J.6
  • 32
    • 0037603113 scopus 로고    scopus 로고
    • Morphogenesis and oncogenesis of MCF-10A mammary epithelial acini grown in three-dimensional basement membrane cultures
    • Debnath J, Muthuswamy SK, Brugge JS: Morphogenesis and oncogenesis of MCF-10A mammary epithelial acini grown in three-dimensional basement membrane cultures. Methods 2003, 30:256-268
    • (2003) Methods , vol.30 , pp. 256-268
    • Debnath, J.1    Muthuswamy, S.K.2    Brugge, J.S.3
  • 33
    • 4043107128 scopus 로고    scopus 로고
    • Mutation and aberrant expression of Caveolin-1 in human oral squamous cell carcinomas and oral cancer cell lines
    • Han SE, Park KH, Lee G, Huh YJ, Min BM: Mutation and aberrant expression of Caveolin-1 in human oral squamous cell carcinomas and oral cancer cell lines. Int J Oncol 2004, 24:435-440
    • (2004) Int J Oncol , vol.24 , pp. 435-440
    • Han, S.E.1    Park, K.H.2    Lee, G.3    Huh, Y.J.4    Min, B.M.5
  • 35
    • 0027988814 scopus 로고
    • The WW domain: A signalling site in dystrophin?
    • Bork P, Sudol M: The WW domain: a signalling site in dystrophin? Trends Biochem Sci 1994, 19:531-533
    • (1994) Trends Biochem Sci , vol.19 , pp. 531-533
    • Bork, P.1    Sudol, M.2
  • 36
    • 0029146950 scopus 로고
    • Characterization of a novel protein-binding module-the WW domain
    • Sudol M, Chen HI, Bougeret C, Einbond A, Bork P: Characterization of a novel protein-binding module-the WW domain. FEBS Lett 1995, 369:67-71
    • (1995) FEBS Lett , vol.369 , pp. 67-71
    • Sudol, M.1    Chen, H.I.2    Bougeret, C.3    Einbond, A.4    Bork, P.5
  • 37
    • 30344437854 scopus 로고    scopus 로고
    • Caveolin-1 deficiency (-/-) conveys premalignant alterations in mammary epithelia, with abnormal lumen formation, growth factor independence, and cell invasiveness
    • Sotgia F, Williams TM, Schubert W, Medina F, Minetti C, Pestell RG, Lisanti MP: Caveolin-1 deficiency (-/-) conveys premalignant alterations in mammary epithelia, with abnormal lumen formation, growth factor independence, and cell invasiveness. Am J Pathol 2006, 168:292-309
    • (2006) Am J Pathol , vol.168 , pp. 292-309
    • Sotgia, F.1    Williams, T.M.2    Schubert, W.3    Medina, F.4    Minetti, C.5    Pestell, R.G.6    Lisanti, M.P.7
  • 38
    • 9444236895 scopus 로고    scopus 로고
    • Minireview: Cyclin D1: Normal and abnormal functions
    • Fu M, Wang C, Li Z, Sakamaki T, Pestell RG: Minireview: Cyclin D1: normal and abnormal functions. Endocrinology 2004, 145:5439-5447
    • (2004) Endocrinology , vol.145 , pp. 5439-5447
    • Fu, M.1    Wang, C.2    Li, Z.3    Sakamaki, T.4    Pestell, R.G.5
  • 43
    • 0035065492 scopus 로고    scopus 로고
    • Mutational and functional analyses reveal that ST7 is a highly conserved tumor-suppressor gene on human chromosome 7q31
    • Zenklusen JC, Conti CJ, Green ED: Mutational and functional analyses reveal that ST7 is a highly conserved tumor-suppressor gene on human chromosome 7q31. Nat Genet 2001, 27:392-398
    • (2001) Nat Genet , vol.27 , pp. 392-398
    • Zenklusen, J.C.1    Conti, C.J.2    Green, E.D.3
  • 46
    • 0038751964 scopus 로고    scopus 로고
    • Absence of caveolin-1 sensitizes mouse skin to carcinogen-induced epidermal hyperplasia and tumor formation
    • Capozza F, Williams TM, Schubert W, McClain S, Bouzahzah B, Sotgia F, Lisanti MP: Absence of caveolin-1 sensitizes mouse skin to carcinogen-induced epidermal hyperplasia and tumor formation. Am J Pathol 2003, 162:2029-2039
    • (2003) Am J Pathol , vol.162 , pp. 2029-2039
    • Capozza, F.1    Williams, T.M.2    Schubert, W.3    McClain, S.4    Bouzahzah, B.5    Sotgia, F.6    Lisanti, M.P.7
  • 47
    • 16344386431 scopus 로고    scopus 로고
    • Caveolin-1 down-regulation activates estrogen receptor alpha expression and leads to 17beta-estradiol-stimulated mammary tumorigenesis
    • Zhang X, Shen P, Coleman M, Zou W, Loggie BW, Smith LM, Wang Z: Caveolin-1 down-regulation activates estrogen receptor alpha expression and leads to 17beta-estradiol-stimulated mammary tumorigenesis. Anticancer Res 2005, 25:369-375
    • (2005) Anticancer Res , vol.25 , pp. 369-375
    • Zhang, X.1    Shen, P.2    Coleman, M.3    Zou, W.4    Loggie, B.W.5    Smith, L.M.6    Wang, Z.7
  • 49
    • 3042525924 scopus 로고    scopus 로고
    • Breast cancer, stem/progenitor cells and the estrogen receptor
    • Dontu G, El-Ashry D, Wicha MS: Breast cancer, stem/progenitor cells and the estrogen receptor. Trends Endocrinol Metab 2004, 15:193-197
    • (2004) Trends Endocrinol Metab , vol.15 , pp. 193-197
    • Dontu, G.1    El-Ashry, D.2    Wicha, M.S.3
  • 50
    • 0347504942 scopus 로고    scopus 로고
    • Epithelial progenitor cell lines as models of normal breast morphogenesis and neoplasia
    • Petersen OW, Gudjonsson T, Villadsen R, Bissell MJ, Ronnov-Jessen L: Epithelial progenitor cell lines as models of normal breast morphogenesis and neoplasia. Cell Prolif 2003, 36(Suppl 1):33-44
    • (2003) Cell Prolif , vol.36 , Issue.SUPPL. 1 , pp. 33-44
    • Petersen, O.W.1    Gudjonsson, T.2    Villadsen, R.3    Bissell, M.J.4    Ronnov-Jessen, L.5
  • 51
    • 11144340909 scopus 로고    scopus 로고
    • A putative human breast stem cell population is enriched for steroid receptor-positive cells
    • Clarke RB, Spence K, Anderson E, Howell A, Okano H, Potten CS: A putative human breast stem cell population is enriched for steroid receptor-positive cells. Dev Biol 2005, 277:443-456
    • (2005) Dev Biol , vol.277 , pp. 443-456
    • Clarke, R.B.1    Spence, K.2    Anderson, E.3    Howell, A.4    Okano, H.5    Potten, C.S.6
  • 52
    • 1842858258 scopus 로고    scopus 로고
    • Differentiation of human alveolar epithelial cells in primary culture: Morphological characterization and synthesis of caveolin-1 and surfactant protein-C
    • Fuchs S, Hollins AJ, Laue M, Schaefer UF, Roemer K, Gumbleton M, Lehr CM: Differentiation of human alveolar epithelial cells in primary culture: morphological characterization and synthesis of caveolin-1 and surfactant protein-C. Cell Tissue Res 2003, 311:31-45
    • (2003) Cell Tissue Res , vol.311 , pp. 31-45
    • Fuchs, S.1    Hollins, A.J.2    Laue, M.3    Schaefer, U.F.4    Roemer, K.5    Gumbleton, M.6    Lehr, C.M.7
  • 53
    • 4344613569 scopus 로고    scopus 로고
    • Identification of genes involved in VEGF-mediated vascular morphogenesis using embryonic stem cell-derived cystic embryoid bodies
    • Ng YS, Ramsauer M, Loureiro RM, D'Amore PA: Identification of genes involved in VEGF-mediated vascular morphogenesis using embryonic stem cell-derived cystic embryoid bodies. Lab Invest 2004, 84:1209-1218
    • (2004) Lab Invest , vol.84 , pp. 1209-1218
    • Ng, Y.S.1    Ramsauer, M.2    Loureiro, R.M.3    D'Amore, P.A.4
  • 54
    • 29244451080 scopus 로고    scopus 로고
    • Caveolin-1-deficient mice have an increased mammary stem cell population with upregulation of Wnt/beta-catenin signaling
    • Sotgia F, Williams TM, Cohen AW, Minetti C, Pestell RG, Lisanti MP: Caveolin-1-deficient mice have an increased mammary stem cell population with upregulation of Wnt/beta-catenin signaling. Cell Cycle 2005, 4:1808-1816
    • (2005) Cell Cycle , vol.4 , pp. 1808-1816
    • Sotgia, F.1    Williams, T.M.2    Cohen, A.W.3    Minetti, C.4    Pestell, R.G.5    Lisanti, M.P.6
  • 55
    • 33646390135 scopus 로고    scopus 로고
    • Genetic ablation of caveolin-1 in mammary epithelial cells increases milk production and hyperactivates STAT5a signaling
    • Sotgia F, Schubert W, Pestell RG, Lisanti MP: Genetic ablation of caveolin-1 in mammary epithelial cells increases milk production and hyperactivates STAT5a signaling. Cancer Biol Ther 2006, 5:292-297
    • (2006) Cancer Biol Ther , vol.5 , pp. 292-297
    • Sotgia, F.1    Schubert, W.2    Pestell, R.G.3    Lisanti, M.P.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.