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Volumn 4, Issue 12, 2005, Pages 1808-1816

Caveolin-1-deficient mice have an increased mammary stem cell population with upregulation of Wnt/β-catenin signaling

Author keywords

Acini formation; Animal models; Caveolae; Caveolin 1; Keratin 6; Mammary progenitor cells; Sca 1; Stem cells; Catenin

Indexed keywords

ATAXIN 1; BETA CATENIN; CAVEOLIN 1; KERATIN; KERATIN 5; KERATIN 6; UNCLASSIFIED DRUG; WNT PROTEIN;

EID: 29244451080     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.4.12.2198     Document Type: Article
Times cited : (66)

References (81)
  • 1
    • 0026454933 scopus 로고
    • Sequence and expression of caveolin, a protein component of caveolae plasma membrane domains phosphorylated on tyrosine in Rous sarcoma virus-transformed fibroblasts
    • USA
    • Glenney Jr JR, Soppet D. Sequence and expression of caveolin, a protein component of caveolae plasma membrane domains phosphorylated on tyrosine in Rous sarcoma virus-transformed fibroblasts. Proc Natl Acad Sci USA 1992; 89:10517-21.
    • (1992) Proc Natl Acad Sci , vol.89 , pp. 10517-10521
    • Glenney Jr., J.R.1    Soppet, D.2
  • 3
    • 0032489443 scopus 로고    scopus 로고
    • Caveolins, a family of scaffolding proteins for organizing "preassembled signaling complexes" at the plasma membrane
    • Okamoto T, Schlegel A, Scherer PE, Lisanti MP. Caveolins, A family of scaffolding proteins for organizing "preassembled signaling complexes" at the plasma membrane. J Biol Chem, (Mini-review) 1998; 273:5419-22.
    • (1998) J Biol Chem, (Mini-review) , vol.273 , pp. 5419-5422
    • Okamoto, T.1    Schlegel, A.2    Scherer, P.E.3    Lisanti, M.P.4
  • 5
    • 0036733284 scopus 로고    scopus 로고
    • Caveolae: From cell biology to animal physiology
    • Razani B, Woodman SE, Lisanti MP. Caveolae: From cell biology to animal physiology. Pharmacol Rev 2002; 54:431-67.
    • (2002) Pharmacol Rev , vol.54 , pp. 431-467
    • Razani, B.1    Woodman, S.E.2    Lisanti, M.P.3
  • 8
    • 0026640940 scopus 로고
    • VIP 21, a 21-kD membrane protein is an integral component of trans-Golgi-network-derived transport vesicles
    • Kurzchalia TV, Dupree P, Parton RG, Kellner R, Virta H, Lehnert M, Simons K. VIP 21, A 21-kD membrane protein is an integral component of trans-Golgi-network-derived transport vesicles. J Cell Biol 1992; 118:1003-14.
    • (1992) J Cell Biol , vol.118 , pp. 1003-1014
    • Kurzchalia, T.V.1    Dupree, P.2    Parton, R.G.3    Kellner, R.4    Virta, H.5    Lehnert, M.6    Simons, K.7
  • 10
    • 0030561979 scopus 로고
    • M-caveolin, a muscle-specific caveolin-related protein
    • Way M, Parton R. M-caveolin, a muscle-specific caveolin-related protein. FEBS Lett 1995; 376:108-12.
    • (1995) FEBS Lett , vol.376 , pp. 108-112
    • Way, M.1    Parton, R.2
  • 11
    • 0030731231 scopus 로고    scopus 로고
    • Interaction of a receptor tyrosine kinase, EGF-R, with caveolins. Caveolin binding negatively regulates tyrosine and serine/threonine kinase activities
    • Couet J, Sargiacomo M, Lisanti MP. Interaction of a receptor tyrosine kinase, EGF-R, with caveolins. Caveolin binding negatively regulates tyrosine and serine/threonine kinase activities. J Biol Chem 1997; 272:30429-38.
    • (1997) J Biol Chem , vol.272 , pp. 30429-30438
    • Couet, J.1    Sargiacomo, M.2    Lisanti, M.P.3
  • 13
    • 15844431258 scopus 로고    scopus 로고
    • Localization of EGF-stimulated Ras/Raf-1 interaction to caveolae membrane
    • Mineo C, James GL, Smart EJ, Anderson RGW. Localization of EGF-stimulated Ras/Raf-1 interaction to caveolae membrane. J Biol Chem 1996; 271:11930-5.
    • (1996) J Biol Chem , vol.271 , pp. 11930-11935
    • Mineo, C.1    James, G.L.2    Smart, E.J.3    Anderson, R.G.W.4
  • 14
    • 0033965898 scopus 로고    scopus 로고
    • Caveolin 1-mediated regulation of receptor tyrosine kinase-associated phosphatidylinositol 3-kinase activity by ceramide
    • Zundel W, Swiersz LM, Giaccia A. Caveolin 1-mediated regulation of receptor tyrosine kinase-associated phosphatidylinositol 3-kinase activity by ceramide. Mol Cell Biol 2000; 20:1507-14.
    • (2000) Mol Cell Biol , vol.20 , pp. 1507-1514
    • Zundel, W.1    Swiersz, L.M.2    Giaccia, A.3
  • 15
    • 0030941001 scopus 로고    scopus 로고
    • Identification of peptide and protein ligands for the caveolin-scaffolding domain. Implications for the interaction of caveolin with caveolae-associated proteins
    • Couet J, Li. S, Okamoto T, Ikezu T, Lisanti MP. Identification of peptide and protein ligands for the caveolin-scaffolding domain. Implications for the interaction of caveolin with caveolae-associated proteins. J Biol Chem 1997; 272:6525-33.
    • (1997) J Biol Chem , vol.272 , pp. 6525-6533
    • Couet, J.1    Li, S.2    Okamoto, T.3    Ikezu, T.4    Lisanti, M.P.5
  • 16
    • 0028953271 scopus 로고
    • Reduction of caveolin and caveolae in oncogenically transformed cells
    • USA
    • Koleske AJ, Baltimore D, Lisanti MP. Reduction of caveolin and caveolae in oncogenically transformed cells. Proc Natl Acad Sci USA 1995; 92:1381-5.
    • (1995) Proc Natl Acad Sci , vol.92 , pp. 1381-1385
    • Koleske, A.J.1    Baltimore, D.2    Lisanti, M.P.3
  • 17
    • 0034649425 scopus 로고    scopus 로고
    • Caveolin-1 expression is Down-regulated in cells ransformed by the human papilloma virus in a p53-dependent manner. Replacement of Caveolin-1 Expression Suppresses HPV-Mediated Cell Transformation
    • Razani B, Altschuler Y, Zhu L, Pestell RG, Mostov KE, Lisanti MP. Caveolin-1 expression is Down-regulated in cells ransformed by the human papilloma virus in a p53-dependent manner. Replacement of Caveolin-1 Expression Suppresses HPV-Mediated Cell Transformation. Biochemistry 2000; 39:13916-24.
    • (2000) Biochemistry , vol.39 , pp. 13916-13924
    • Razani, B.1    Altschuler, Y.2    Zhu, L.3    Pestell, R.G.4    Mostov, K.E.5    Lisanti, M.P.6
  • 19
    • 0032546319 scopus 로고    scopus 로고
    • Tumor cell growth inhibition by caveolin reexpression in human breast cancer cells
    • Lee SW, Reimer CL, Oh P, Campbell DB, Schnitzer JE. Tumor cell growth inhibition by caveolin reexpression in human breast cancer cells. Oncogene 1998; 16:1391-7.
    • (1998) Oncogene , vol.16 , pp. 1391-1397
    • Lee, S.W.1    Reimer, C.L.2    Oh, P.3    Campbell, D.B.4    Schnitzer, J.E.5
  • 20
    • 0034667394 scopus 로고    scopus 로고
    • Caveolin-1 levels are down-regulated in human colon tumors, and ectopic expression of caveolin-1 in colon carcinoma cell lines reduces cell tumorigenicity
    • Bender FC, Reymond MA, Bron C, Quest A. Caveolin-1 levels are down-regulated in human colon tumors, and ectopic expression of caveolin-1 in colon carcinoma cell lines reduces cell tumorigenicity. Cancer Res 2000; 60:5870-8.
    • (2000) Cancer Res , vol.60 , pp. 5870-5878
    • Bender, F.C.1    Reymond, M.A.2    Bron, C.3    Quest, A.4
  • 21
    • 0034726960 scopus 로고    scopus 로고
    • Downmodulation of caveolin-1 expression in human ovarian carcinoma is directly related to alpha-folate receptor overexpression
    • Bagnoli M, Tomassetti A, Figini M, Flati S, Dolo V, Canevari S, Miotti S. Downmodulation of caveolin-1 expression in human ovarian carcinoma is directly related to alpha-folate receptor overexpression. Oncogene 2000; 19:4754-63.
    • (2000) Oncogene , vol.19 , pp. 4754-4763
    • Bagnoli, M.1    Tomassetti, A.2    Figini, M.3    Flati, S.4    Dolo, V.5    Canevari, S.6    Miotti, S.7
  • 23
    • 0038751964 scopus 로고    scopus 로고
    • Absence of caveolin-1 sensitizes mouse skin to carcinogen-induced epidermal hyperplasia and tumor formation
    • Capozza F, Williams TM, Schubert W, McClain S, Bouzahzah B, Sotgia F, Lisanti MP. Absence of caveolin-1 sensitizes mouse skin to carcinogen-induced epidermal hyperplasia and tumor formation. Am J Pathol 2003; 162:2029-39.
    • (2003) Am J Pathol , vol.162 , pp. 2029-2039
    • Capozza, F.1    Williams, T.M.2    Schubert, W.3    McClain, S.4    Bouzahzah, B.5    Sotgia, F.6    Lisanti, M.P.7
  • 24
    • 0031758918 scopus 로고    scopus 로고
    • Genes encoding human caveolin-1 and -2 are colocalized to the D7S522 locus (7q31.1), a known fragile site (FRA7G) that is frequently deleted in human cancers
    • Engelman JA, Zhang XL, Lisanti MP. Genes encoding human caveolin-1 and -2 are colocalized to the D7S522 locus (7q31.1), a known fragile site (FRA7G) that is frequently deleted in human cancers. FEBS Lett 1998; 436:403-10.
    • (1998) FEBS Lett , vol.436 , pp. 403-410
    • Engelman, J.A.1    Zhang, X.L.2    Lisanti, M.P.3
  • 25
    • 0028091664 scopus 로고
    • (C-A)n microsatellite repeat D7S522 is the most commonly deleted region in human primary breast cancer
    • USA
    • Zenklusen JC, Bieche I, Lidereau R, Conti CJ. (C-A)n microsatellite repeat D7S522 is the most commonly deleted region in human primary breast cancer. Proc Natl Acad Sci USA 1994; 91:12155-8.
    • (1994) Proc Natl Acad Sci , vol.91 , pp. 12155-12158
    • Zenklusen, J.C.1    Bieche, I.2    Lidereau, R.3    Conti, C.J.4
  • 26
    • 0028641304 scopus 로고
    • Loss of heterozygosity in human primary prostate carcinomas: A possible tumor suppressor gene at 7q31.1
    • Zenklusen JC, Thompson JC, Troncoso P, Kagan J, Conti CJ. Loss of heterozygosity in human primary prostate carcinomas: A possible tumor suppressor gene at 7q31.1. Cancer Res 1994; 54:6370-3.
    • (1994) Cancer Res , vol.54 , pp. 6370-6373
    • Zenklusen, J.C.1    Thompson, J.C.2    Troncoso, P.3    Kagan, J.4    Conti, C.J.5
  • 27
    • 0028929987 scopus 로고
    • Frequent loss of heterozygosity in human primary squamous cell and colon carcinomas at 7q31.1: Evidence for a broad range tumor suppressor gene
    • Zenklusen JC, Thompson JC, Klein-Szanto AJ, Conti CJ. Frequent loss of heterozygosity in human primary squamous cell and colon carcinomas at 7q31.1: Evidence for a broad range tumor suppressor gene. Cancer Res 1995; 55:1347-50.
    • (1995) Cancer Res , vol.55 , pp. 1347-1350
    • Zenklusen, J.C.1    Thompson, J.C.2    Klein-Szanto, A.J.3    Conti, C.J.4
  • 28
    • 0029121078 scopus 로고
    • Allelic loss at 7q31.1 in human primary ovarian carcinomas suggests the existence of a tumor suppressor gene
    • Zenklusen JC, Weitzel JN, Ball HG, Conti CJ. Allelic loss at 7q31.1 in human primary ovarian carcinomas suggests the existence of a tumor suppressor gene. Oncogene 1995; 11:359-63.
    • (1995) Oncogene , vol.11 , pp. 359-363
    • Zenklusen, J.C.1    Weitzel, J.N.2    Ball, H.G.3    Conti, C.J.4
  • 31
    • 0030700907 scopus 로고    scopus 로고
    • Loss of heterozygosity on the long arm of human chromosome 7 in sporadic renal cell carcinomas
    • Shridhar V, Sun QC, Miller OJ, Kalemkerian GP, Petros J, Smith DI. Loss of heterozygosity on the long arm of human chromosome 7 in sporadic renal cell carcinomas. Oncogene 1997; 15:2727-33.
    • (1997) Oncogene , vol.15 , pp. 2727-2733
    • Shridhar, V.1    Sun, Q.C.2    Miller, O.J.3    Kalemkerian, G.P.4    Petros, J.5    Smith, D.I.6
  • 32
    • 0031892622 scopus 로고    scopus 로고
    • Fish mapping of YAC clones at human chromosomal band 7q31.2: Identification of YACS spanning FRA7G within the common region of LOH in breast and prostate cancer
    • Huang H, Qian C, Jenkins RB, Smith DI. Fish mapping of YAC clones at human chromosomal band 7q31.2: Identification of YACS spanning FRA7G within the common region of LOH in breast and prostate cancer. Genes Chromosomes Cancet 1998; 21:152-9.
    • (1998) Genes Chromosomes Cancet , vol.21 , pp. 152-159
    • Huang, H.1    Qian, C.2    Jenkins, R.B.3    Smith, D.I.4
  • 35
    • 0036791604 scopus 로고    scopus 로고
    • Caveolin-1 mutations (P132L and null) and the pathogenesis of breast cancer: Caveolin-1 (P132L) behaves in a dominant-negative manner and caveolin-1 (-/-) null mice show mammary epithelial cell hyperplasia
    • Lee H, Park DS, Razani B, Russell RG, Pestell RG, Lisanti MP. Caveolin-1 mutations (P132L and null) and the pathogenesis of breast cancer: Caveolin-1 (P132L) behaves in a dominant-negative manner and caveolin-1 (-/-) null mice show mammary epithelial cell hyperplasia. Am J Pathol 2002; 161:1357-69.
    • (2002) Am J Pathol , vol.161 , pp. 1357-1369
    • Lee, H.1    Park, D.S.2    Razani, B.3    Russell, R.G.4    Pestell, R.G.5    Lisanti, M.P.6
  • 36
    • 2642549186 scopus 로고    scopus 로고
    • Combined loss of INK4a and caveolin-1 synergistically enhances cell proliferation and oncogene-induced tumorigenesis: Role of INK4a/CAV-1 in mammary epithelial cell hyperplasia
    • Williams TM, Lee H, Cheung MW, Cohen AW, Razani B, Iyengar P, Scherer PE, Pestell RG, Lisanti MP. Combined loss of INK4a and caveolin-1 synergistically enhances cell proliferation and oncogene-induced tumorigenesis: Role of INK4a/CAV-1 in mammary epithelial cell hyperplasia. J Biol Chem 2004; 279:24745-56.
    • (2004) J Biol Chem , vol.279 , pp. 24745-24756
    • Williams, T.M.1    Lee, H.2    Cheung, M.W.3    Cohen, A.W.4    Razani, B.5    Iyengar, P.6    Scherer, P.E.7    Pestell, R.G.8    Lisanti, M.P.9
  • 38
    • 19944366937 scopus 로고    scopus 로고
    • Caveolin-1 gene disruption promotes mammary tumorigenesis and dramatically enhances lung metastasis in Vivo role of Cav-1 in cell invasiveness and matrix metalloproteinase (MMP-2/9) secretion
    • Williams TM, Medina F, Badano I, Hazan RB, Hutchinson J, Muller WJ, Chopra NG, Scherer PE, Pestell RG, Lisanti MP. Caveolin-1 gene disruption promotes mammary tumorigenesis and dramatically enhances lung metastasis in Vivo role of Cav-1 in cell invasiveness and matrix metalloproteinase (MMP-2/9) secretion. J Biol Chem 2004.
    • (2004) J Biol Chem
    • Williams, T.M.1    Medina, F.2    Badano, I.3    Hazan, R.B.4    Hutchinson, J.5    Muller, W.J.6    Chopra, N.G.7    Scherer, P.E.8    Pestell, R.G.9    Lisanti, M.P.10
  • 39
    • 0036798278 scopus 로고    scopus 로고
    • Caveolin-1-deficient mice show accelerated mammary gland development during pregnancy, premature lactation, and hyperactivation of the Jak-2/STAT5a signaling cascade
    • Park DS, Lee H, Frank PG, Razani B, Nguyen AV, Parlow AF, Russell RG, Hulit J, Pestell RG, Lisanti MP. Caveolin-1-deficient mice show accelerated mammary gland development during pregnancy, premature lactation, and hyperactivation of the Jak-2/STAT5a signaling cascade. Mol Biol Cell 2002; 13:3416-30.
    • (2002) Mol Biol Cell , vol.13 , pp. 3416-3430
    • Park, D.S.1    Lee, H.2    Frank, P.G.3    Razani, B.4    Nguyen, A.V.5    Parlow, A.F.6    Russell, R.G.7    Hulit, J.8    Pestell, R.G.9    Lisanti, M.P.10
  • 40
    • 0037603113 scopus 로고    scopus 로고
    • Morphogenesis and oncogenesis of MCF-10A mammary epithelial acini grown in three-dimensional basement membrane cultures
    • Debnath J, Muthuswamy SK, Brugge JS. Morphogenesis and oncogenesis of MCF-10A mammary epithelial acini grown in three-dimensional basement membrane cultures. Methods 2003; 30:256-68.
    • (2003) Methods , vol.30 , pp. 256-268
    • Debnath, J.1    Muthuswamy, S.K.2    Brugge, J.S.3
  • 41
    • 0034839704 scopus 로고    scopus 로고
    • The interplay of matrix metalloproteinases, morphogens and growth factors is necessary for branching of mammary epithelial cells
    • Simian M, Hirai Y, Navre M, Werb Z, Lochter A, Bissell MJ. The interplay of matrix metalloproteinases, morphogens and growth factors is necessary for branching of mammary epithelial cells. Development 2001; 128:3117-31.
    • (2001) Development , vol.128 , pp. 3117-3131
    • Simian, M.1    Hirai, Y.2    Navre, M.3    Werb, Z.4    Lochter, A.5    Bissell, M.J.6
  • 42
    • 0024505367 scopus 로고
    • Functional differentiation and alveolar morphogenesis of primary mammary cultures on reconstituted basement membrane
    • Barcellos-Hoff MH, Aggeler J, Ram TG, Bissell MJ. Functional differentiation and alveolar morphogenesis of primary mammary cultures on reconstituted basement membrane. Development 1989; 105:223-35.
    • (1989) Development , vol.105 , pp. 223-235
    • Barcellos-Hoff, M.H.1    Aggeler, J.2    Ram, T.G.3    Bissell, M.J.4
  • 43
    • 0036153330 scopus 로고    scopus 로고
    • Normal and tumor-derived myoepithehal cells differ in their ability to interact with luminal breast epithelial cells for polarity and basement membrane deposition
    • Gudjonsson T, Ronnov-Jessen L, Villadsen R, Rank F, Bissell MJ, Petersen OW. Normal and tumor-derived myoepithehal cells differ in their ability to interact with luminal breast epithelial cells for polarity and basement membrane deposition. J Cell Sci 2002; 115:39-50.
    • (2002) J Cell Sci , vol.115 , pp. 39-50
    • Gudjonsson, T.1    Ronnov-Jessen, L.2    Villadsen, R.3    Rank, F.4    Bissell, M.J.5    Petersen, O.W.6
  • 44
    • 30344437854 scopus 로고    scopus 로고
    • Caveolin-1 deficiency (-/-) conveys premalignant alterations in mammary epithelia, with abnormal 3D lumen formation, EGF-independent growth, and increased branching capacity
    • 2006; In press
    • Sotgia F, Williams TM, Schubert W, Medina F, Minetti C, Pestell RG, Lisanti MP. Caveolin-1 deficiency (-/-) conveys premalignant alterations in mammary epithelia, with abnormal 3D lumen formation, EGF-independent growth, and increased branching capacity. Am J Pathol 2006; In press.
    • Am J Pathol
    • Sotgia, F.1    Williams, T.M.2    Schubert, W.3    Medina, F.4    Minetti, C.5    Pestell, R.G.6    Lisanti, M.P.7
  • 45
    • 18944407603 scopus 로고    scopus 로고
    • Mammary stem cells, self-renewal pathways, and carcinogenesis
    • Liu S, Dontu G, Wicha MS. Mammary stem cells, self-renewal pathways, and carcinogenesis. Breast Cancer Res 2005; 7:86-95.
    • (2005) Breast Cancer Res , vol.7 , pp. 86-95
    • Liu, S.1    Dontu, G.2    Wicha, M.S.3
  • 48
    • 0142061064 scopus 로고    scopus 로고
    • Stem cells: To be and not to be
    • Lin H. Stem cells: To be and not to be. Nature 2003; 425:353-5.
    • (2003) Nature , vol.425 , pp. 353-355
    • Lin, H.1
  • 50
    • 0034614576 scopus 로고    scopus 로고
    • Stem cells: Units of development, units of regeneration, and units in evolution
    • Weissman IL. Stem cells: Units of development, units of regeneration, and units in evolution. Cell 2000; 100:157-68.
    • (2000) Cell , vol.100 , pp. 157-168
    • Weissman, I.L.1
  • 51
    • 0023922373 scopus 로고
    • Purification and characterization of mouse hematopoietic stem cells
    • Spangrude GJ, Heimfeld S, Weissman IL. Purification and characterization of mouse hematopoietic stem cells. Science 1988; 241:58-62.
    • (1988) Science , vol.241 , pp. 58-62
    • Spangrude, G.J.1    Heimfeld, S.2    Weissman, I.L.3
  • 52
    • 0036570144 scopus 로고    scopus 로고
    • Sca-1(pos) cells in the mouse mammary gland represent an enriched progenitor cell population
    • Welm BE, Tepera SB, Venezia T, Graubert TA, Rosen JM, Goodell MA. Sca-1(pos) cells in the mouse mammary gland represent an enriched progenitor cell population. Dev Biol 2002; 245:42-56.
    • (2002) Dev Biol , vol.245 , pp. 42-56
    • Welm, B.E.1    Tepera, S.B.2    Venezia, T.3    Graubert, T.A.4    Rosen, J.M.5    Goodell, M.A.6
  • 54
    • 0025415270 scopus 로고
    • Differential keratin gene expression in developing, differentiating, preneoplastic, and neoplastic mouse mammary epithelium
    • Smith GH, Mehrel T, Roop DR. Differential keratin gene expression in developing, differentiating, preneoplastic, and neoplastic mouse mammary epithelium. Cell Growth Differ 1990; 1:161-70.
    • (1990) Cell Growth Differ , vol.1 , pp. 161-170
    • Smith, G.H.1    Mehrel, T.2    Roop, D.R.3
  • 57
    • 21044455045 scopus 로고    scopus 로고
    • Mammary epithelial cell transformation: Insights from cell culture and mouse models
    • Dimri G, Band H, Band V. Mammary epithelial cell transformation: Insights from cell culture and mouse models. Breast Cancer Res 2005; 7:171-9.
    • (2005) Breast Cancer Res , vol.7 , pp. 171-179
    • Dimri, G.1    Band, H.2    Band, V.3
  • 61
    • 1842858258 scopus 로고    scopus 로고
    • Differentiation of human alveolar epithelial cells in primary culture: Morphological characterization and synthesis of caveolin-1 and surfactant protein-C
    • Fuchs S, Hollins AJ, Laue M, Schaefer UF, Roemer K, Gumbleton M, Leht CM. Differentiation of human alveolar epithelial cells in primary culture: Morphological characterization and synthesis of caveolin-1 and surfactant protein-C. Cell Tissue Res 2003;311:31-45.
    • (2003) Cell Tissue Res , vol.311 , pp. 31-45
    • Fuchs, S.1    Hollins, A.J.2    Laue, M.3    Schaefer, U.F.4    Roemer, K.5    Gumbleton, M.6    Leht, C.M.7
  • 62
    • 0033533501 scopus 로고    scopus 로고
    • Caveolin-1 expression and caveolae biogenesis during cell transdifferentiation in lung alveolar epithelial primary cultures
    • Campbell L, Hollins AJ, Al-Eid A, Newman GR, von Ruhland C, Gumbleton M. Caveolin-1 expression and caveolae biogenesis during cell transdifferentiation in lung alveolar epithelial primary cultures. Biochem Biophys Res Commun 1999; 262:744-51.
    • (1999) Biochem Biophys Res Commun , vol.262 , pp. 744-751
    • Campbell, L.1    Hollins, A.J.2    Al-Eid, A.3    Newman, G.R.4    Von Ruhland, C.5    Gumbleton, M.6
  • 64
    • 0032842826 scopus 로고    scopus 로고
    • Coexpression of scavenger receptor-BI and caveolin-1 is associated with enhanced selective cholesteryl ester uptake in THP-1 macrophages
    • Matveev S, van der Westhuyzen DR, Smart EJ. Coexpression of scavenger receptor-BI and caveolin-1 is associated with enhanced selective cholesteryl ester uptake in THP-1 macrophages. J Lipid Res 1999; 40:1647-54.
    • (1999) J Lipid Res , vol.40 , pp. 1647-1654
    • Matveev, S.1    Van Der Westhuyzen, D.R.2    Smart, E.J.3
  • 65
    • 4344613569 scopus 로고    scopus 로고
    • Identification of genes involved in VEGF-mediated vascular morphogenesis using embryonic stem cell-derived cystic embryoid bodies
    • Ng YS, Ramsauer M, Loureiro RM, D'Amore PA. Identification of genes involved in VEGF-mediated vascular morphogenesis using embryonic stem cell-derived cystic embryoid bodies. Lab Invest 2004; 84:1209-18.
    • (2004) Lab Invest , vol.84 , pp. 1209-1218
    • Ng, Y.S.1    Ramsauer, M.2    Loureiro, R.M.3    D'Amore, P.A.4
  • 66
    • 0037155864 scopus 로고    scopus 로고
    • Caveolin-1 expression enhances endothelial capillary tubule formation
    • Liu J, Wang XB, Park DS, Lisanti MP. Caveolin-1 expression enhances endothelial capillary tubule formation. J Biol Chem 2002; 277:10661-8.
    • (2002) J Biol Chem , vol.277 , pp. 10661-10668
    • Liu, J.1    Wang, X.B.2    Park, D.S.3    Lisanti, M.P.4
  • 69
    • 0036323674 scopus 로고    scopus 로고
    • Expression of caveolin-1 induces premature cellular senescence in primary cultures of murine fibroblasts
    • Volonte D, Zhang K, Lisanti MP, Galbiati F. Expression of caveolin-1 induces premature cellular senescence in primary cultures of murine fibroblasts. Mol Biol Cell 2002; 13:2502-17.
    • (2002) Mol Biol Cell , vol.13 , pp. 2502-2517
    • Volonte, D.1    Zhang, K.2    Lisanti, M.P.3    Galbiati, F.4
  • 70
    • 0036066584 scopus 로고    scopus 로고
    • Gastrointestinal stem cells
    • Brittan M, Wright NA. Gastrointestinal stem cells. J Pathol 2002; 197:492-509.
    • (2002) J Pathol , vol.197 , pp. 492-509
    • Brittan, M.1    Wright, N.A.2
  • 72
    • 19544375032 scopus 로고    scopus 로고
    • Wnt control of stem cells and differentiation in the intestinal epithelium
    • Pinto D, Clevers H. Wnt control of stem cells and differentiation in the intestinal epithelium. Exp Cell Res 2005; 306:357-63.
    • (2005) Exp Cell Res , vol.306 , pp. 357-363
    • Pinto, D.1    Clevers, H.2
  • 73
    • 23244432429 scopus 로고    scopus 로고
    • BMP signaling and stem cell regulation
    • In press
    • Zhang J, Li L. BMP signaling and stem cell regulation. Dev Biol 2005; In press.
    • (2005) Dev Biol
    • Zhang, J.1    Li, L.2
  • 74
    • 1642570244 scopus 로고    scopus 로고
    • The transforming activity of Wnt effectors correlates with their ability to induce the accumulation of mammary progenitor cells
    • USA
    • Liu BY, McDermott SP, Khwaja SS, Alexander CM. The transforming activity of Wnt effectors correlates with their ability to induce the accumulation of mammary progenitor cells. Proc Natl Acad Sci USA 2004; 101:4158-63.
    • (2004) Proc Natl Acad Sci , vol.101 , pp. 4158-4163
    • Liu, B.Y.1    McDermott, S.P.2    Khwaja, S.S.3    Alexander, C.M.4
  • 75
    • 0034725590 scopus 로고    scopus 로고
    • Caveolin-1 expression inhibits Wnt/beta-catenin/ Lef-1 signaling by recruiting beta-catenin to caveolae membrane domains
    • Galbiati F, Volonte D, Brown AM, Weinstein DE, Ben-Ze'ev A, Pestell RG, Lisanti MP. Caveolin-1 expression inhibits Wnt/beta-catenin/ Lef-1 signaling by recruiting beta-catenin to caveolae membrane domains. J Biol Chem 2000; 275:23368-77.
    • (2000) J Biol Chem , vol.275 , pp. 23368-23377
    • Galbiati, F.1    Volonte, D.2    Brown, A.M.3    Weinstein, D.E.4    Ben-Ze'ev, A.5    Pestell, R.G.6    Lisanti, M.P.7
  • 77
    • 0032921038 scopus 로고    scopus 로고
    • Restricted high level expression of Tcf-4 protein in intestinal and mammary gland epithelium
    • Barker N, Huls G, Korinek V, Clevers H. Restricted high level expression of Tcf-4 protein in intestinal and mammary gland epithelium. Am J Pathol 1999; 154:29-35.
    • (1999) Am J Pathol , vol.154 , pp. 29-35
    • Barker, N.1    Huls, G.2    Korinek, V.3    Clevers, H.4
  • 80
    • 0345736990 scopus 로고    scopus 로고
    • Down regulation of caveolin-1 function by EGF leads to the loss of E-cadherin, increased transcriptional activity of beta-catenin, and enhanced tumor cell invasion
    • Lu Z, Ghosh S, Wang Z, Hunter T. Down regulation of caveolin-1 function by EGF leads to the loss of E-cadherin, increased transcriptional activity of beta-catenin, and enhanced tumor cell invasion. Cancer Cell 2003; 4:499-515.
    • (2003) Cancer Cell , vol.4 , pp. 499-515
    • Lu, Z.1    Ghosh, S.2    Wang, Z.3    Hunter, T.4


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