-
1
-
-
79957909052
-
Effect of pioglitazone on altered expression of A beta metabolism-associated molecules in the brain of fructose-drinking rats, a rodent model of insulin resistance
-
Luo DZ, Hou XY, Hou L, Wang MX, Xu S, et al. (2011) Effect of pioglitazone on altered expression of A beta metabolism-associated molecules in the brain of fructose-drinking rats, a rodent model of insulin resistance. European Journal of Pharmacology 664: 14-19.
-
(2011)
European Journal of Pharmacology
, vol.664
, pp. 14-19
-
-
Luo, D.Z.1
Hou, X.Y.2
Hou, L.3
Wang, M.X.4
Xu, S.5
-
2
-
-
4444276735
-
Clearance of Alzheimer's A beta peptide: The many roads to perdition
-
Tanzi RE, Moir RD, Wagner SL, (2004) Clearance of Alzheimer's A beta peptide: The many roads to perdition. Neuron 43: 605-608.
-
(2004)
Neuron
, vol.43
, pp. 605-608
-
-
Tanzi, R.E.1
Moir, R.D.2
Wagner, S.L.3
-
3
-
-
0035399887
-
Insulin-degrading enzyme: embarking on amyloid destruction
-
Kurochkin IV, (2001) Insulin-degrading enzyme: embarking on amyloid destruction. Trends in Biochemical Sciences 26: 421-425.
-
(2001)
Trends in Biochemical Sciences
, vol.26
, pp. 421-425
-
-
Kurochkin, I.V.1
-
4
-
-
0037390039
-
Insulin-degrading enzyme regulates the levels of insulin, amyloid beta-protein, and the beta-amyloid precursor protein intracellular domain in vivo
-
Farris W, Mansourian S, Chang Y, Lindsley L, Eckman EA, et al. (2003) Insulin-degrading enzyme regulates the levels of insulin, amyloid beta-protein, and the beta-amyloid precursor protein intracellular domain in vivo. Proceedings of the National Academy of Sciences of the United States of America 100: 4162-4167.
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, pp. 4162-4167
-
-
Farris, W.1
Mansourian, S.2
Chang, Y.3
Lindsley, L.4
Eckman, E.A.5
-
5
-
-
70449564488
-
Insulin-Degrading Enzyme: Structure-Function Relationship and its Possible Roles in Health and Disease
-
Fernandez-Gamba A, Leal MC, Morelli L, Castano EM, (2009) Insulin-Degrading Enzyme: Structure-Function Relationship and its Possible Roles in Health and Disease. Current Pharmaceutical Design 15: 3644-3655.
-
(2009)
Current Pharmaceutical Design
, vol.15
, pp. 3644-3655
-
-
Fernandez-Gamba, A.1
Leal, M.C.2
Morelli, L.3
Castano, E.M.4
-
6
-
-
77955846215
-
Differential cerebral deposition of IDE and NEP in sporadic and familial Alzheimer's disease
-
Dorfman VB, Pasquini L, Riudavets M, Lopez-Costa JJ, Villegas A, et al. (2010) Differential cerebral deposition of IDE and NEP in sporadic and familial Alzheimer's disease. Neurobiology of Aging 31: 1743-1757.
-
(2010)
Neurobiology of Aging
, vol.31
, pp. 1743-1757
-
-
Dorfman, V.B.1
Pasquini, L.2
Riudavets, M.3
Lopez-Costa, J.J.4
Villegas, A.5
-
7
-
-
69449102820
-
Neprilysin and Insulin-Degrading Enzyme Levels Are Increased in Alzheimer Disease in Relation to Disease Severity
-
Miners JS, Baig S, Tayler H, Kehoe PG, Love S, (2009) Neprilysin and Insulin-Degrading Enzyme Levels Are Increased in Alzheimer Disease in Relation to Disease Severity. Journal of Neuropathology and Experimental Neurology 68: 902-914.
-
(2009)
Journal of Neuropathology and Experimental Neurology
, vol.68
, pp. 902-914
-
-
Miners, J.S.1
Baig, S.2
Tayler, H.3
Kehoe, P.G.4
Love, S.5
-
8
-
-
75149166216
-
Insulin-Degrading Enzyme Sorting in Exosomes: A Secretory Pathway for a Key Brain Amyloid-beta Degrading Protease
-
Bulloj A, Leal MC, Xu HX, Castano EM, Morelli L, (2010) Insulin-Degrading Enzyme Sorting in Exosomes: A Secretory Pathway for a Key Brain Amyloid-beta Degrading Protease. J Alzheimer's Dis 19: 79-95.
-
(2010)
J Alzheimer's Dis
, vol.19
, pp. 79-95
-
-
Bulloj, A.1
Leal, M.C.2
Xu, H.X.3
Castano, E.M.4
Morelli, L.5
-
9
-
-
0344549853
-
Ginseng pharmacology-Multiple constituents and multiple actions
-
Attele AS, Wu JA, Yuan CS, (1999) Ginseng pharmacology-Multiple constituents and multiple actions. Biochemical Pharmacology 58: 1685-1693.
-
(1999)
Biochemical Pharmacology
, vol.58
, pp. 1685-1693
-
-
Attele, A.S.1
Wu, J.A.2
Yuan, C.S.3
-
10
-
-
83455245428
-
Multi-faced neuroprotective effects of Ginsenoside Rg1 in an Alzheimer mouse model
-
Fang F, Chen X, Huang T, Lue LF, Luddy JS, et al. (2012) Multi-faced neuroprotective effects of Ginsenoside Rg1 in an Alzheimer mouse model. Biochimica et Biophysica Acta 1822: 286-292.
-
(2012)
Biochimica Et Biophysica Acta
, vol.1822
, pp. 286-292
-
-
Fang, F.1
Chen, X.2
Huang, T.3
Lue, L.F.4
Luddy, J.S.5
-
11
-
-
70449674742
-
Ginsenoside Rg1 inhibits beta-secretase activity in vitro and protects against A beta-induced cytotoxicity in PC12 cells
-
Wang YH, Du GH, (2009) Ginsenoside Rg1 inhibits beta-secretase activity in vitro and protects against A beta-induced cytotoxicity in PC12 cells. Journal of Asian Natural Products Research 11: 604-612.
-
(2009)
Journal of Asian Natural Products Research
, vol.11
, pp. 604-612
-
-
Wang, Y.H.1
Du, G.H.2
-
12
-
-
0035869723
-
Ginsenoside Rb1 and Rg1 improve spatial learning and increase hippocampal synaptophysin level in mice
-
Mook-Jung I, Hong HS, Boo JH, Lee KH, Yun SH, et al. (2001) Ginsenoside Rb1 and Rg1 improve spatial learning and increase hippocampal synaptophysin level in mice. Journal of Neuroscience Research 63: 509-515.
-
(2001)
Journal of Neuroscience Research
, vol.63
, pp. 509-515
-
-
Mook-Jung, I.1
Hong, H.S.2
Boo, J.H.3
Lee, K.H.4
Yun, S.H.5
-
13
-
-
77149166322
-
Ginsenoside Rg1 Attenuates Amyloid-beta Content, Regulates PKA/CREB Activity, and Improves Cognitive Performance in SAMP8 Mice
-
Shi YQ, Huang TW, Chen LM, Pan XD, Zhang J, et al. (2010) Ginsenoside Rg1 Attenuates Amyloid-beta Content, Regulates PKA/CREB Activity, and Improves Cognitive Performance in SAMP8 Mice. Journal of Alzheimers Disease 19: 977-989.
-
(2010)
Journal of Alzheimers Disease
, vol.19
, pp. 977-989
-
-
Shi, Y.Q.1
Huang, T.W.2
Chen, L.M.3
Pan, X.D.4
Zhang, J.5
-
14
-
-
79955053353
-
Ginsenoside Rg1 protects primary cultured rat hippocampal neurons from cell apoptosis induced by beta beta-amyloid protein
-
Gong L, Li SL, Li H, Zhang L, (2011) Ginsenoside Rg1 protects primary cultured rat hippocampal neurons from cell apoptosis induced by beta beta-amyloid protein. Pharmaceutical Biology 49: 501-507.
-
(2011)
Pharmaceutical Biology
, vol.49
, pp. 501-507
-
-
Gong, L.1
Li, S.L.2
Li, H.3
Zhang, L.4
-
15
-
-
78650415275
-
Ginsenoside Rg1 protects against hydrogen peroxide-induced cell death in PC12 cells via inhibiting NF-kappa B activation
-
Liu QA, Kou JP, Yu BY, (2011) Ginsenoside Rg1 protects against hydrogen peroxide-induced cell death in PC12 cells via inhibiting NF-kappa B activation. Neurochemistry International 58: 119-125.
-
(2011)
Neurochemistry International
, vol.58
, pp. 119-125
-
-
Liu, Q.A.1
Kou, J.P.2
Yu, B.Y.3
-
16
-
-
70350721715
-
Effects of Ginsenoside Rg1 on nuclear factor-kappa B activity in beta amyloid protein-treated neural cells
-
Chen YB, Zhang DP, Feng M, Wang Q, Cheng SY, et al. (2009) Effects of Ginsenoside Rg1 on nuclear factor-kappa B activity in beta amyloid protein-treated neural cells. Neural Regeneration Research 4: 590-596.
-
(2009)
Neural Regeneration Research
, vol.4
, pp. 590-596
-
-
Chen, Y.B.1
Zhang, D.P.2
Feng, M.3
Wang, Q.4
Cheng, S.Y.5
-
17
-
-
13444293396
-
Anti-amnestic and anti-aging effects of ginsenoside Rg1 and Rb1 and its mechanism of action
-
Cheng Y, Shen LH, Zhang JT, (2005) Anti-amnestic and anti-aging effects of ginsenoside Rg1 and Rb1 and its mechanism of action. Acta Pharmacologica Sinica 26: 143-149.
-
(2005)
Acta Pharmacologica Sinica
, vol.26
, pp. 143-149
-
-
Cheng, Y.1
Shen, L.H.2
Zhang, J.T.3
-
18
-
-
77955654408
-
The study of ginsenoside on PPAR gamma expression of mononuclear macrophage in type 2 diabetes
-
Ni HX, Yu NJ, Yang XH, (2010) The study of ginsenoside on PPAR gamma expression of mononuclear macrophage in type 2 diabetes. Molecular Biology Reports 37: 2975-2979.
-
(2010)
Molecular Biology Reports
, vol.37
, pp. 2975-2979
-
-
Ni, H.X.1
Yu, N.J.2
Yang, X.H.3
-
19
-
-
66349132459
-
PPAR gamma transcriptionally regulates the expression of insulin-degrading enzyme in primary neurons
-
Du J, Zhang L, Liu SB, Zhang C, Huang XQ, et al. (2009) PPAR gamma transcriptionally regulates the expression of insulin-degrading enzyme in primary neurons. Biochemical and Biophysical Research Communications 383: 485-490.
-
(2009)
Biochemical and Biophysical Research Communications
, vol.383
, pp. 485-490
-
-
Du, J.1
Zhang, L.2
Liu, S.B.3
Zhang, C.4
Huang, X.Q.5
-
20
-
-
79954724910
-
Paeonol increases levels of cortical cytochrome oxidase and vascular actin and improves behavior in a rat model of Alzheimer's disease
-
Zhou J, Zhou L, Hou DR, Tang JC, Sun JJ, et al. (2011) Paeonol increases levels of cortical cytochrome oxidase and vascular actin and improves behavior in a rat model of Alzheimer's disease. Brain Research 1388: 141-147.
-
(2011)
Brain Research
, vol.1388
, pp. 141-147
-
-
Zhou, J.1
Zhou, L.2
Hou, D.R.3
Tang, J.C.4
Sun, J.J.5
-
21
-
-
79952622790
-
Genistein ameliorates learning and memory deficits in amyloid beta((1-40)) rat model of Alzheimer's disease
-
Bagheri M, Joghataei MT, Mohseni S, Roghani M, (2011) Genistein ameliorates learning and memory deficits in amyloid beta((1-40)) rat model of Alzheimer's disease. Neurobiology of Learning and Memory 95: 270-276.
-
(2011)
Neurobiology of Learning and Memory
, vol.95
, pp. 270-276
-
-
Bagheri, M.1
Joghataei, M.T.2
Mohseni, S.3
Roghani, M.4
-
22
-
-
0031577191
-
Effects of ginsenosides on maze performance and brain choline acetyltransferase activity in scopolamine-treated young rats and aged rats
-
Yamaguchi Y, Higashi M, Kobayashi H, (1997) Effects of ginsenosides on maze performance and brain choline acetyltransferase activity in scopolamine-treated young rats and aged rats. European Journal of Pharmacology 329: 37-41.
-
(1997)
European Journal of Pharmacology
, vol.329
, pp. 37-41
-
-
Yamaguchi, Y.1
Higashi, M.2
Kobayashi, H.3
-
23
-
-
79954994070
-
Telmisartan, a dual ARB/partial PPAR-gamma agonist, protects myocardium from ischaemic reperfusion injury in experimental diabetes
-
Goyal SN, Bharti S, Bhatia J, Nag TC, Ray R, et al. (2011) Telmisartan, a dual ARB/partial PPAR-gamma agonist, protects myocardium from ischaemic reperfusion injury in experimental diabetes. Diabetes Obesity & Metabolism 13: 533-541.
-
(2011)
Diabetes Obesity & Metabolism
, vol.13
, pp. 533-541
-
-
Goyal, S.N.1
Bharti, S.2
Bhatia, J.3
Nag, T.C.4
Ray, R.5
-
24
-
-
34548142159
-
Colchicines-induced neurotoxicity as an animal model of sporadic dementia of Alzheimer's type
-
Kumar A, Seghal N, Naidu PS, Padi SSV, Goyal R, (2007) Colchicines-induced neurotoxicity as an animal model of sporadic dementia of Alzheimer's type. Pharmacological Reports 59: 274-283.
-
(2007)
Pharmacological Reports
, vol.59
, pp. 274-283
-
-
Kumar, A.1
Seghal, N.2
Naidu, P.S.3
Padi, S.S.V.4
Goyal, R.5
-
25
-
-
77957233161
-
Intramuscular delivery of a single chain antibody gene prevents brain A beta deposition and cognitive impairment in a mouse model of Alzheimer's disease
-
Wang YJ, Gao CY, Yang MA, Liu XH, Sun Y, et al. (2010) Intramuscular delivery of a single chain antibody gene prevents brain A beta deposition and cognitive impairment in a mouse model of Alzheimer's disease. Brain Behavior and Immunity 24: 1281-1293.
-
(2010)
Brain Behavior and Immunity
, vol.24
, pp. 1281-1293
-
-
Wang, Y.J.1
Gao, C.Y.2
Yang, M.A.3
Liu, X.H.4
Sun, Y.5
-
26
-
-
23444457119
-
Chemokine receptor 5 antagonist D-Ala-peptide T-amide reduces microglia and astrocyte activation within the hippocampus in a neuroinflammatory rat model of Alzheimer's disease
-
Rosi S, Pert CB, Ruff MR, McGann-Gramling K, Wenk GL, (2005) Chemokine receptor 5 antagonist D-Ala-peptide T-amide reduces microglia and astrocyte activation within the hippocampus in a neuroinflammatory rat model of Alzheimer's disease. Neuroscience 134: 671-676.
-
(2005)
Neuroscience
, vol.134
, pp. 671-676
-
-
Rosi, S.1
Pert, C.B.2
Ruff, M.R.3
McGann-Gramling, K.4
Wenk, G.L.5
-
27
-
-
0037221379
-
The role of insulin resistance in the pathogenesis of Alzheimer's disease-Implications for treatment
-
Watson GS, Craft S, (2003) The role of insulin resistance in the pathogenesis of Alzheimer's disease-Implications for treatment. Cns Drugs 17: 27-45.
-
(2003)
Cns Drugs
, vol.17
, pp. 27-45
-
-
Watson, G.S.1
Craft, S.2
-
28
-
-
77952423753
-
Rosiglitazone Rescues Memory Impairment in Alzheimer's Transgenic Mice: Mechanisms Involving a Reduced Amyloid and Tau Pathology
-
Escribano L, Simon AM, Gimeno E, Cuadrado-Tejedor M, de Maturana RL, et al. (2010) Rosiglitazone Rescues Memory Impairment in Alzheimer's Transgenic Mice: Mechanisms Involving a Reduced Amyloid and Tau Pathology. Neuropsychopharmacology 35: 1593-1604.
-
(2010)
Neuropsychopharmacology
, vol.35
, pp. 1593-1604
-
-
Escribano, L.1
Simon, A.M.2
Gimeno, E.3
Cuadrado-Tejedor, M.4
de Maturana, R.L.5
-
29
-
-
1542373533
-
Prospective study of type 2 diabetes and cognitive decline in women aged 70-81 years
-
Logroscino G, Kang JH, Grodstein F, (2004) Prospective study of type 2 diabetes and cognitive decline in women aged 70-81 years. British Medical Journal 328: 548-551.
-
(2004)
British Medical Journal
, vol.328
, pp. 548-551
-
-
Logroscino, G.1
Kang, J.H.2
Grodstein, F.3
-
30
-
-
3242765976
-
Fasting insulin and incident dementia in an elderly population of Japanese-American men
-
Peila R, Rodriguez BL, White LR, Launer LJ, (2004) Fasting insulin and incident dementia in an elderly population of Japanese-American men. Neurology 63: 228-233.
-
(2004)
Neurology
, vol.63
, pp. 228-233
-
-
Peila, R.1
Rodriguez, B.L.2
White, L.R.3
Launer, L.J.4
-
31
-
-
0034333018
-
Cognition and synaptic plasticity in diabetes mellitus
-
Gispen WH, Biessels GJ, (2000) Cognition and synaptic plasticity in diabetes mellitus. Trends in Neurosciences 23: 542-549.
-
(2000)
Trends in Neurosciences
, vol.23
, pp. 542-549
-
-
Gispen, W.H.1
Biessels, G.J.2
-
32
-
-
0035847269
-
Immunohistochemical distribution of the receptor for advanced glycation end products in neurons and astrocytes in Alzheimer's disease
-
Sasaki N, Toki S, Chowei H, Saito T, Nakano N, et al. (2001) Immunohistochemical distribution of the receptor for advanced glycation end products in neurons and astrocytes in Alzheimer's disease. Brain Research 888: 256-262.
-
(2001)
Brain Research
, vol.888
, pp. 256-262
-
-
Sasaki, N.1
Toki, S.2
Chowei, H.3
Saito, T.4
Nakano, N.5
-
33
-
-
29844432266
-
Insulin, insulin-degrading enzyme and amyloid-beta peptide in Alzheimer's disease: review and hypothesis
-
Qiu WQ, Folstein MF, (2006) Insulin, insulin-degrading enzyme and amyloid-beta peptide in Alzheimer's disease: review and hypothesis. Neurobiology of Aging 27: 190-198.
-
(2006)
Neurobiology of Aging
, vol.27
, pp. 190-198
-
-
Qiu, W.Q.1
Folstein, M.F.2
-
34
-
-
0038038865
-
Insulin increases CSF A beta 42 levels in normal older adults
-
Watson GS, Peskind ER, Asthana S, Purganan K, Wait C, et al. (2003) Insulin increases CSF A beta 42 levels in normal older adults. Neurology 60: 1899-1903.
-
(2003)
Neurology
, vol.60
, pp. 1899-1903
-
-
Watson, G.S.1
Peskind, E.R.2
Asthana, S.3
Purganan, K.4
Wait, C.5
-
35
-
-
0037219221
-
Reduced hippocampal insulin-degrading enzyme in late-onset Alzheimer's disease is associated with the apolipoprotein E-epsilon 4 allele
-
Cook DG, Leverenz JB, McMillan PJ, Kulstad JJ, Ericksen S, et al. (2003) Reduced hippocampal insulin-degrading enzyme in late-onset Alzheimer's disease is associated with the apolipoprotein E-epsilon 4 allele. American Journal of Pathology 162: 313-319.
-
(2003)
American Journal of Pathology
, vol.162
, pp. 313-319
-
-
Cook, D.G.1
Leverenz, J.B.2
McMillan, P.J.3
Kulstad, J.J.4
Ericksen, S.5
-
36
-
-
77958093616
-
Rosiglitazone and pioglitazone increase fracture risk in women and men with type 2 diabetes
-
Aubert RE, Herrera V, Chen W, Haffner SM, Pendergrass M, (2010) Rosiglitazone and pioglitazone increase fracture risk in women and men with type 2 diabetes. Diabetes Obesity & Metabolism 12: 716-721.
-
(2010)
Diabetes Obesity & Metabolism
, vol.12
, pp. 716-721
-
-
Aubert, R.E.1
Herrera, V.2
Chen, W.3
Haffner, S.M.4
Pendergrass, M.5
-
37
-
-
34250865768
-
Rosiglitazone evaluated for cardiovascular outcomes-An interim analysis
-
Home PD, Pocock SJ, Beck-Nielsen H, Gomis R, Hanefeld M, et al. (2007) Rosiglitazone evaluated for cardiovascular outcomes-An interim analysis. New England Journal of Medicine 357: 28-38.
-
(2007)
New England Journal of Medicine
, vol.357
, pp. 28-38
-
-
Home, P.D.1
Pocock, S.J.2
Beck-Nielsen, H.3
Gomis, R.4
Hanefeld, M.5
-
38
-
-
78751627542
-
In older patients, rosiglitazone was associated with increased risk for stroke, heart failure, and mortality compared with pioglitazone
-
Wang AT, Smith SA (2010) In older patients, rosiglitazone was associated with increased risk for stroke, heart failure, and mortality compared with pioglitazone. Annals of Internal Medicine 153.
-
(2010)
Annals of Internal Medicine
, vol.153
-
-
Wang, A.T.1
Smith, S.A.2
-
39
-
-
79956217900
-
Risk of Bladder Cancer Among Diabetic Patients Treated With Pioglitazone Interim report of a longitudinal cohort study
-
Lewis JD, Ferrara A, Peng T, Hedderson M, Bilker WB, et al. (2011) Risk of Bladder Cancer Among Diabetic Patients Treated With Pioglitazone Interim report of a longitudinal cohort study. Diabetes Care 34: 916-922.
-
(2011)
Diabetes Care
, vol.34
, pp. 916-922
-
-
Lewis, J.D.1
Ferrara, A.2
Peng, T.3
Hedderson, M.4
Bilker, W.B.5
-
40
-
-
34247100646
-
Insulin degrading enzyme activity selectively decreases in the hippocampal formation of cases at high risk to develop Alzheimer's disease
-
Zhao Z, Xiang ZM, Haroutunian V, Buxbaum JD, Stetka B, et al. (2007) Insulin degrading enzyme activity selectively decreases in the hippocampal formation of cases at high risk to develop Alzheimer's disease. Neurobiology of Aging 28: 824-830.
-
(2007)
Neurobiology of Aging
, vol.28
, pp. 824-830
-
-
Zhao, Z.1
Xiang, Z.M.2
Haroutunian, V.3
Buxbaum, J.D.4
Stetka, B.5
-
41
-
-
0034038036
-
Degradation of soluble amyloid beta-peptides 1-40, 1-42, and the Dutch variant 1-40Q by insulin degrading enzyme from Alzheimer disease and control brains
-
Perez A, Morelli L, Cresto JC, Castano EM, (2000) Degradation of soluble amyloid beta-peptides 1-40, 1-42, and the Dutch variant 1-40Q by insulin degrading enzyme from Alzheimer disease and control brains. Neurochemical Research 25: 247-255.
-
(2000)
Neurochemical Research
, vol.25
, pp. 247-255
-
-
Perez, A.1
Morelli, L.2
Cresto, J.C.3
Castano, E.M.4
-
42
-
-
43849097891
-
Increased expression of A beta degrading enzyme IDE in the cortex of transgenic mice with Alzheimer's disease-like neuropathology
-
Vepsalainen S, Hiltunen M, Helisalmi S, Wang J, van Groen T, et al. (2008) Increased expression of A beta degrading enzyme IDE in the cortex of transgenic mice with Alzheimer's disease-like neuropathology. Neuroscience Letters 438: 216-220.
-
(2008)
Neuroscience Letters
, vol.438
, pp. 216-220
-
-
Vepsalainen, S.1
Hiltunen, M.2
Helisalmi, S.3
Wang, J.4
van Groen, T.5
-
43
-
-
0035877747
-
Neprilysin degrades both amyloid beta peptides 1-40 and 1-42 most rapidly and efficiently among thiorphan- and phosphoramidon-sensitive endopeptidases
-
Shirotani K, Tsubuki S, Iwata N, Takaki Y, Harigaya W, et al. (2001) Neprilysin degrades both amyloid beta peptides 1-40 and 1-42 most rapidly and efficiently among thiorphan- and phosphoramidon-sensitive endopeptidases. Journal of Biological Chemistry 276: 21895-21901.
-
(2001)
Journal of Biological Chemistry
, vol.276
, pp. 21895-21901
-
-
Shirotani, K.1
Tsubuki, S.2
Iwata, N.3
Takaki, Y.4
Harigaya, W.5
-
44
-
-
0037444432
-
Neprilysin gene transfer reduces human amyloid pathology in transgenic mice
-
Marr RA, Rockenstein E, Mukherjee A, Kindy MS, Hersh LB, et al. (2003) Neprilysin gene transfer reduces human amyloid pathology in transgenic mice. Journal of Neuroscience 23: 1992-1996.
-
(2003)
Journal of Neuroscience
, vol.23
, pp. 1992-1996
-
-
Marr, R.A.1
Rockenstein, E.2
Mukherjee, A.3
Kindy, M.S.4
Hersh, L.B.5
-
45
-
-
0035816707
-
Degradation of the Alzheimer's amyloid beta peptide by endothelin-converting enzyme
-
Eckman EA, Reed DK, Eckman CB, (2001) Degradation of the Alzheimer's amyloid beta peptide by endothelin-converting enzyme. Journal of Biological Chemistry 276: 24540-24548.
-
(2001)
Journal of Biological Chemistry
, vol.276
, pp. 24540-24548
-
-
Eckman, E.A.1
Reed, D.K.2
Eckman, C.B.3
-
46
-
-
0037462769
-
Alzheimer's disease beta-amyloid peptide is increased in mice deficient in endothelin-converting enzyme
-
Eckman EA, Watson M, Marlow L, Sambamurti K, Eckman CB, (2003) Alzheimer's disease beta-amyloid peptide is increased in mice deficient in endothelin-converting enzyme. Journal of Biological Chemistry 278: 2081-2084.
-
(2003)
Journal of Biological Chemistry
, vol.278
, pp. 2081-2084
-
-
Eckman, E.A.1
Watson, M.2
Marlow, L.3
Sambamurti, K.4
Eckman, C.B.5
-
47
-
-
0035930538
-
Angiotensin-converting enzyme degrades Alzheimer amyloid beta-peptide (A beta); Retards A beta aggregation, deposition, fibril formation, and inhibits cytotoxicity
-
Hu JG, Igarashi A, Kamata M, Nakagawa H, (2001) Angiotensin-converting enzyme degrades Alzheimer amyloid beta-peptide (A beta); Retards A beta aggregation, deposition, fibril formation, and inhibits cytotoxicity. Journal of Biological Chemistry 276: 47863-47868.
-
(2001)
Journal of Biological Chemistry
, vol.276
, pp. 47863-47868
-
-
Hu, J.G.1
Igarashi, A.2
Kamata, M.3
Nakagawa, H.4
-
48
-
-
0033621048
-
Plasmin cleavage of the amyloid beta-protein: Alteration of secondary structure and stimulation of tissue plasminogen activator activity
-
Van Nostrand WE, Porter M, (1999) Plasmin cleavage of the amyloid beta-protein: Alteration of secondary structure and stimulation of tissue plasminogen activator activity. Biochemistry 38: 11570-11576.
-
(1999)
Biochemistry
, vol.38
, pp. 11570-11576
-
-
Van Nostrand, W.E.1
Porter, M.2
-
49
-
-
18544410708
-
The plasmin system is induced by and degrades amyloid-beta aggregates
-
Tucker HM, Kihiko M, Caldwell JN, Wright S, Kawarabayashi T, et al. (2000) The plasmin system is induced by and degrades amyloid-beta aggregates. Journal of Neuroscience 20: 3937-3946.
-
(2000)
Journal of Neuroscience
, vol.20
, pp. 3937-3946
-
-
Tucker, H.M.1
Kihiko, M.2
Caldwell, J.N.3
Wright, S.4
Kawarabayashi, T.5
-
50
-
-
33747680357
-
Matrix metalloproteinase-9 degrades amyloid-beta fibrils in vitro and compact plaques in situ
-
Yan P, Hu XY, Song HW, Yin KJ, Bateman RJ, et al. (2006) Matrix metalloproteinase-9 degrades amyloid-beta fibrils in vitro and compact plaques in situ. Journal of Biological Chemistry 281: 24566-24574.
-
(2006)
Journal of Biological Chemistry
, vol.281
, pp. 24566-24574
-
-
Yan, P.1
Hu, X.Y.2
Song, H.W.3
Yin, K.J.4
Bateman, R.J.5
-
51
-
-
65649105035
-
Clearance of Amyloid-beta Peptide Across the Blood-Brain Barrier: Implication for Therapies in Alzheimer's Disease
-
Deane R, Bell RD, Sagare A, Zlokovic BV, (2009) Clearance of Amyloid-beta Peptide Across the Blood-Brain Barrier: Implication for Therapies in Alzheimer's Disease. Cns & Neurological Disorders-Drug Targets 8: 16-30.
-
(2009)
Cns & Neurological Disorders-Drug Targets
, vol.8
, pp. 16-30
-
-
Deane, R.1
Bell, R.D.2
Sagare, A.3
Zlokovic, B.V.4
-
52
-
-
2542475986
-
Clearing amyloid through the blood-brain barrier
-
Zlokovic BV, (2004) Clearing amyloid through the blood-brain barrier. Journal of Neurochemistry 89: 807-811.
-
(2004)
Journal of Neurochemistry
, vol.89
, pp. 807-811
-
-
Zlokovic, B.V.1
|