Effects of Ginsenoside Rg1 on nuclear factor-kappa B activity in beta amyloid protein-treated neural cells

Neural Regeneration Research

Volumn 4, Issue 8, 2009, Pages 590-596

  Chen, Yunbo ^a   Zhang, Dapeng ^a   Feng, Mei ^a   Wang, Qi ^a   Cheng, Shuyi ^a   Liang, Weixiong ^a   Wen, Zehuai ^a  

^a GUANGZHOU UNIVERSITY OF CHINESE MEDICINE   (China)

Author keywords

Alzheimer's disease; Ginsenoside Rg1; Neuroprotection; Nuclear factor B; amyloid protein

Indexed keywords

AMYLOID BETA PROTEIN[25-35]; GINSENOSIDE RG 1; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN;

ALZHEIMER DISEASE; ANIMAL CELL; ARTICLE; ASTROCYTE; BRAIN NERVE CELL; CELL ACTIVITY; CELL STRUCTURE; CELL VIABILITY; CONTROLLED STUDY; DRUG EFFECT; HIPPOCAMPUS; IMMUNOFLUORESCENCE TEST; IMMUNOHISTOCHEMISTRY; NEUROPROTECTION; NEWBORN; NONHUMAN; RAT;

EID: 70350721715     PISSN: 16735374     EISSN: None     Source Type: Journal    
DOI: 10.3969/j.issn.1673-5374.2009.08.005     Document Type: Article

References (22)

1. Sen R, Baltimore D. Multiple nuclear factors interact with the immunoglobulin enhancer sequences. Cell. 1986;46(5):705-716. (Pubitemid 16020062)
2. Baldwin AS Jr. The NF-kappa B and I kappa B proteins: new discoveries and insights. Annu Rev Immunol. 1996;14:649-683. (Pubitemid 26130197)
3. Lee SY, Son DJ, Lee YK, et al. Inhibitory effect of sesaminol glucosides on lipopolysaccharide-induced NF-kappaB activation and target gene expression in cultured rat astrocytes. Neurosci Res. 2006;56(2):204-212.
4. Lezoualc'h F, Sagara Y, Holsboer F, et al. High constitutive NF-kappaB activity mediates resistance to oxidative stress in neuronal cells. J Neurosci. 1998;18(9):3224-3232.
5. Guan J, Lai CM, Li SP. A rapid method for the simultaneous determination of 11 saponins in Panax notoginseng using ultra performance liquid chromatography. J Pharm Biomed Anal. 2007;44(4):996-1000.
6. Cheng Y, Shen LH, Zhang JT. Anti-amnestic and anti-aging effects of ginsenoside Rg1 and Rb1 and its mechanism of action. Acta Pharmacol Sin. 2005;26(2):143-149. (Pubitemid 40203956)
7. Wang XY, Chen J, Zhang JT. Effect of ginsenoside Rg1 on learning and memory impairment induced by beta-amyloid peptide(25-35) and its mechanism of action. Yao Xue Xue Bao. 2001;36(1):1-4. (Pubitemid 33631931)
8. The Ministry of Science and Technology of the People's Republic of China. Regulations for the Administration of Affairs Concerning Experimental Animals. 1988-10-31.
9. Banker GA, Cowan WM. Rat hippocampal neurons in dispersed cell culture. Brain Res. 1977;126(3):397-1342
10. Schmechel DE, Brightman MW, Marangos PJ. Neurons switch from non-neuronal enolase to neuron-specific enolase during differentiation. Brain Res. 1980;190(1):195-214. (Pubitemid 10085561)
11. McCarthy KD, de Vellis J. Preparation of separate astroglial and oligodendroglial cell cultures from rat cerebral tissue. J Cell Biol. 1980;85(3):890-902.
12. Raff MC, Fields KL, Hakomori SI, et al. Cell-type-specific markers for distinguishing and studying neurons and the major classes of glial cells in culture. Brain Res. 1979;174(2):283-308.
13. Zhong ZG, Liu MC, Lai SL. Effect of bushen yizhi recipe on neurotransmitter release in A beta segment neurotoxin induced NG108-15 cellular model of Alzheimer disease. Zhongguo Zhong Xi Yi Jie He Za Zhi. 2002;22(1):50-53.
14. Takeno S, Hirakawa K, Ueda T, et al. Nuclear factor-kappa B activation in the nasal polyp epithelium: relationship to local cytokine gene expression. Laryngoscope. 2002;112(1):53-58. (Pubitemid 34037738)
15. Brinton RD, Wang JM. Preclinical analyses of the therapeutic potential of allopregnanolone to promote neurogenesis in vitro and in vivo in transgenic mouse model of Alzheimer's disease. Curr Alzheimer Res. 2006;3(1):11-17.
16. Chong YH, Shin YJ, Lee EO, et al. ERK1/2 activation mediates Abeta oligomer-induced neurotoxicity via caspase-3 activation and tau cleavage in rat organotypic hippocampal slice cultures. J Biol Chem. 2006;281(29):20315-20325.
17. Vieira MN, Forny-Germano L, Saraiva LM, et al. Soluble oligomers from a non-disease related protein mimic Abeta-induced tau hyperphosphorylation and neurodegeneration. J Neurochem. 2007;103(2):736-748. (Pubitemid 47498038)
18. Dahlgren KN, Manelli AM, Stine WB Jr, et al. Oligomeric and fibrillar species of amyloid-beta peptides differentially affect neuronal viability. J Biol Chem. 2002;277(35):32046-32053.
19. Peng XS, Chen XC, Huang JS, et al. The effect of Ginsenoside Rg1 on abnormal phosphorylation of tau in rat's hippocampal neurons induced by aggregated Aβ25-35. Zhongguo Yaolixue Tongbao. 2005;21(3):299-305.
20. Liu M, Zhang JT. Protective effects of ginsenoside Rb1 and Rg1 on cultured hippocampal neurons. Yao Xue Xue Bao. 1995;30(9):674-678.
21. 25-35. Guangzhou Zhongyiyao Daxue Xuebao. 2007;24(2):126-131.
22. Ghribi O. The role of the endoplasmic reticulum in the accumulation of beta-amyloid peptide in Alzheimer's disease. Curr Mol Med. 2006;6(1):119-133.