Interferon block to HIV-1 transduction in macrophages despite SAMHD1 degradation and high deoxynucleoside triphosphates supply

Retrovirology

Volumn 10, Issue 1, 2013, Pages

  Dragin, Loic ^a,b,c   Nguyen, Laura Anh ^d   Lahouassa, Hichem ^a,b,c   Sourisce, Adèle ^a,b,c   Kim, Baek ^d   Ramirez, Bertha Cecilia ^a,b,c   Margottin Goguet, Florence ^a,b,c  

^a INSTITUT COCHIN   (France)

^b CNRS   (France)

^c UNIVERSITÉ PARIS DESCARTES   (France)

^d UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

Author keywords

HIV; Interferon; Restriction; SAMHD1

Indexed keywords

ALPHA INTERFERON; DEOXYNUCLEOSIDE TRIPHOSPHATE; HOST FACTOR; HUMAN IMMUNODEFICIENCY VIRUS PROTEIN; NUCLEOSIDE TRIPHOSPHATE; SAMHD1 PROTEIN; UNCLASSIFIED DRUG; VPX PROTEIN;

ARTICLE; CD4+ T LYMPHOCYTE; CONTROLLED STUDY; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; MACROPHAGE; MONOCYTE; NONHUMAN; PROTEIN DEGRADATION; VIRAL GENE DELIVERY SYSTEM;

CD4-POSITIVE T-LYMPHOCYTES; CELLS, CULTURED; HIV-1; HUMANS; INTERFERON-ALPHA; MACROPHAGES; MONOMERIC GTP-BINDING PROTEINS; NUCLEOTIDES; PROTEOLYSIS; TRANSDUCTION, GENETIC; VIRAL REGULATORY AND ACCESSORY PROTEINS;

HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 2;

EID: 84874685203     PISSN: None     EISSN: 17424690     Source Type: Journal    
DOI: 10.1186/1742-4690-10-30     Document Type: Article

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