Systematic identification of type I and type II interferon-induced antiviral factors

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 11, 2012, Pages 4239-4244

  Liu, Su Yang ^a   Sanchez, David Jesse ^b   Aliyari, Roghiyh ^a   Lu, Sun ^c   Cheng, Genhong ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b WESTERN UNIVERSITY OF HEALTH SCIENCES   (United States)

^c Guangzhou FulenGen Co Ltd   (China)

Author keywords

Antiviral effectors; Interferon stimulated genes; Murine gammaherpes virus 68

Indexed keywords

APOLIPOPROTEIN B MESSENGER RNA EDITING ENZYME CATALYTIC POLYPEPTIDE 3F; APOLIPOPROTEIN B MESSENGER RNA EDITING ENZYME CATALYTIC POLYPEPTIDE 3G; BONE MORPHOGENETIC PROTEIN 2; CASP2 PROTEIN; CD64 ANTIGEN; CH25H PROTEIN; G PROTEIN COUPLED RECEPTOR 146; HEAT SHOCK PROTEIN 110; IFIH1 PROTEIN; IFITM3 PROTEIN; INTERFERON REGULATORY FACTOR 1; INTERFERON STIMULATED GENE FACTOR; INTERFERON STIMULATED GENE FACTOR 20; LY6E PROTEIN; MGAT1 PROTEIN; MITD1 PROTEIN; POLIOVIRUS RECEPTOR RELATED PROTEIN 4; POLY ADP RIBOSE POLYMERASE 11; POLY ADP RIBOSE POLYMERASE 12; PROMYELOCYTIC LEUKEMIA PROTEIN; RECOMBINANT ALPHA INTERFERON; RECOMBINANT GAMMA INTERFERON; RETINOIC ACID INDUCIBLE PROTEIN I; SLFN12 PROTEIN; TANK BINDING KINASE 1; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR MAFK; TRANSPORTER ASSOCIATED WITH ANTIGEN PROCESSING 1; TRIM62 PROTEIN; UNCLASSIFIED DRUG; USP2 PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIVIRAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DNA VIRUS; FIBROBLAST; GAMMAHERPESVIRINAE; GENE EXPRESSION; GENETIC SCREENING; HUMAN; HUMAN CELL; LIFE CYCLE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; RNA VIRUS; VESICULAR STOMATITIS VIRUS; VIROGENESIS; VIRUS REPLICATION;

ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; BONE MARROW CELLS; DNA VIRUSES; FIBROBLASTS; FLOW CYTOMETRY; GENE EXPRESSION REGULATION; HEK293 CELLS; HUMANS; INTERFERON TYPE I; INTERFERON-GAMMA; MACROPHAGES; MICE; MICE, INBRED C57BL; VESICULOVIRUS;

DNA VIRUSES; MURINAE; MURINE HEPATITIS VIRUS; RNA VIRUSES; VESICULAR STOMATITIS VIRUS;

EID: 84863285086     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1114981109     Document Type: Article

References (28)

1. van den Broek MF, Müller U, Huang S, Zinkernagel RM, Aguet M (1995) Immune defence in mice lacking type I and/or type II interferon receptors. Immunol Rev 148(1):5-18. (Pubitemid 26010539)
2. Sadler AJ, Williams BRG (2008) Interferon-inducible antiviral effectors. Nat Rev Immunol 8:559-568. (Pubitemid 351913674)
3. Schroder K, Hertzog PJ, Ravasi T, Hume DA (2004) Interferon-γ: An overview of signals, mechanisms and functions. J Leukoc Biol 75(2):163-189. (Pubitemid 38174573)
4. Schoggins JW, et al. (2011) A diverse range of gene products are effectors of the type I interferon antiviral response. Nature 472:481-485.
5. Flaño E, Kim I-J, Woodland DL, Blackman MA (2002) γ-Herpesvirus latency is preferentially maintained in splenic germinal center and memory B cells. J Exp Med 196: 1363-1372. (Pubitemid 35375555)
6. Meraz MA, et al. (1996) Targeted disruption of the Stat1 gene in mice reveals unexpected physiologic specificity in the JAK-STAT signaling pathway. Cell 84:431-442. (Pubitemid 26058568)
7. Xie ZL, et al. (2011) Co-transfection and tandem transfection of HEK293A cells for overexpression and RNAi experiments. Cell Biol Int 35(3):187-192.
8. Yoneyama M, et al. (2005) Shared and unique functions of the DExD/H-box helicases RIG-I, MDA5, and LGP2 in antiviral innate immunity. J Immunol 175:2851-2858. (Pubitemid 41170502)
9. Miyamoto M, et al. (1988) Regulated expression of a gene encoding a nuclear factor, IRF-1, that specifically binds to IFN-β gene regulatory elements. Cell 54:903-913.
10. Hwang S, et al. (2008) Persistent gammaherpesvirus replication and dynamic interaction with the host in vivo. J Virol 82:12498-12509.
11. Park C, Li S, Cha E, Schindler C (2000) Immune response in Stat2 knockout mice. Immunity 13:795-804. (Pubitemid 32041802)
12. Takaoka A, et al. (2000) Cross talk between interferon-γ and -α/β signaling components in caveolar membrane domains. Science 288:2357-2360. (Pubitemid 30448158)
13. Müller U, et al. (1994) Functional role of type I and type II interferons in antiviral defense. Science 264:1918-1921. (Pubitemid 24245635)
14. Banerjee AK (1987) Transcription and replication of rhabdoviruses. Microbiol Rev 51 (1):66-87.
15. Barr JN, Whelan SP, Wertz GW (2002) Transcriptional control of the RNA-dependent RNA polymerase of vesicular stomatitis virus. Biochim Biophys Acta 1577:337-353. (Pubitemid 35223223)
16. Negrete OA, et al. (2005) EphrinB2 is the entry receptor for Nipah virus, an emergent deadly paramyxovirus. Nature 436:401-405. (Pubitemid 41059050)
17. Wu T-T, Usherwood EJ, Stewart JP, Nash AA, Sun R (2000) Rta of murine gamma-herpesvirus 68 reactivates the complete lytic cycle from latency. J Virol 74:3659-3667. (Pubitemid 30180310)
18. Dutia BM, Allen DJ, Dyson H, Nash AA (1999) Type I interferons and IRF-1 play a critical role in the control of a gammaherpesvirus infection. Virology 261(2):173-179. (Pubitemid 29431770)
19. Sarawar SR, et al. (1997) γ interferon is not essential for recovery from acute infection with murine gammaherpesvirus 68. J Virol 71:3916-3921. (Pubitemid 27172406)
20. Taniguchi T, Takaoka A (2002) The interferon-α/β system in antiviral responses: A multimodal machinery of gene regulation by the IRF family of transcription factors. Curr Opin Immunol 14(1):111-116. (Pubitemid 34085114)
21. Wang X, Lybarger L, Connors R, Harris MR, Hansen TH (2004) Model for the interaction of gammaherpesvirus 68 RING-CH finger protein mK3 with major histocompatibility complex class I and the peptide-loading complex. J Virol 78:8673-8686. (Pubitemid 39025133)
22. Boname JM, de Lima BD, Lehner PJ, Stevenson PG (2004) Viral degradation of the MHC class I peptide loading complex. Immunity 20:305-317. (Pubitemid 38388232)
23. Yamaguchi K, et al. (1999) XIAP, a cellular member of the inhibitor of apoptosis protein family, links the receptors to TAB1-TAK1 in the BMP signaling pathway. EMBO J 18:179-187. (Pubitemid 29005034)
24. Brown HJ, et al. (2003) NF-κB inhibits gammaherpesvirus lytic replication. J Virol 77:8532-8540. (Pubitemid 36871481)
25. Scherle PA, Dorshkind K, Witte ON (1990) Clonal lymphoid progenitor cell lines expressing the BCR/ABL oncogene retain full differentiative function. Proc Natl Acad Sci USA 87:1908-1912.
26. Zarnegar BJ, et al. (2008) Noncanonical NF-κB activation requires coordinated assembly of a regulatory complex of the adaptors cIAP1, cIAP2, TRAF2 and TRAF3 and the kinase NIK. Nat Immunol 9:1371-1378.
27. Takada A, et al. (1997) A system for functional analysis of Ebola virus glycoprotein. Proc Natl Acad Sci USA 94:14764-14769. (Pubitemid 28041448)
28. Pavlidis P, Noble WS (2003) Matrix2png: A utility for visualizing matrix data. Bioinformatics 19:295-296. (Pubitemid 36181920)