The Vpx lentiviral accessory protein targets SAMHD1 for degradation in the nucleus

Journal of Virology

Volumn 86, Issue 23, 2012, Pages 12552-12560

  Hofmann, Henning ^a   Logue, Eric C ^a   Bloch, Nicolin ^a   Daddacha, Waaqo ^b   Polsky, Sylvie B ^a   Schultz, Megan L ^a   Kim, Baek ^a   Landau, Nathaniel R ^a  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HYDROLASE; LEPTOMYCIN B; STERILE ALPHA MOTIF DOMAIN AND HD DOMAIN CONTAINING PROTEIN 1; UNCLASSIFIED DRUG; VIRAL PROTEIN X; VIRUS PROTEIN;

AMINO ACID SEQUENCE; ARTICLE; CELL ASSAY; CONTROLLED STUDY; EXPRESSION VECTOR; HUMAN; IMMUNOBLOTTING; MOLECULAR CLONING; MOUSE; NONHUMAN; NUCLEAR LOCALIZATION SIGNAL; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; SEQUENCE ANALYSIS; UBIQUITINATION; VIRUS CELL INTERACTION;

AMINO ACID SEQUENCE; CELL NUCLEUS; CULLIN PROTEINS; HELA CELLS; HUMANS; IMMUNOBLOTTING; IMMUNOPRECIPITATION; MICROSCOPY, FLUORESCENCE; MONOMERIC GTP-BINDING PROTEINS; NUCLEAR LOCALIZATION SIGNALS; PLASMIDS; PROTEOLYSIS; UBIQUITIN-PROTEIN LIGASES; UBIQUITINATION; VIRAL REGULATORY AND ACCESSORY PROTEINS;

HUMAN IMMUNODEFICIENCY VIRUS 2; SIMIAN IMMUNODEFICIENCY VIRUS;

EID: 84869217288     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.01657-12     Document Type: Article

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