The human immunodeficiency virus type 2 Vpx protein usurps the CUL4A-DDB1DCAF1 ubiquitin ligase to overcome a postentry block in macrophage infection

Journal of Virology

Volumn 83, Issue 10, 2009, Pages 4854-4860

  Bergamaschi, Anna ^a   Ayinde, Diana ^b,c   David, Annie ^a   Le Rouzic, Erwann ^b,c   Morel, Marina ^b,c   Collin, Gilles ^d   Descamps, Diane ^d,e   Damond, Florence ^d   Brun Vezinet, Françoise ^d,e   Nisole, Sebastien ^b,c   Margottin Goguet, Florence ^b,c   Pancino, Gianfranco ^a   Transy, Catherine ^b,c  

^a INSTITUT PASTEUR   (France)

^b INSTITUT COCHIN   (France)

^c INSERM   (France)

^d BICHAT HOSPITAL   (France)

^e UNIVERSITÉ PARIS DESCARTES   (France)

Author keywords

[No Author keywords available]

Indexed keywords

UBIQUITIN PROTEIN LIGASE; UNCLASSIFIED DRUG; VIRUS PROTEIN; VPX PROTEIN; CUL4A PROTEIN, HUMAN; CULLIN; DDB1 PROTEIN, HUMAN; DNA BINDING PROTEIN; VPX PROTEIN, HUMAN IMMUNODEFICIENCY VIRUS 2;

ARTICLE; CONTROLLED STUDY; GENOME; HOST; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 2; MACROPHAGE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN FUNCTION; REGULATORY MECHANISM; REVERSE TRANSCRIPTION; SIMIAN IMMUNODEFICIENCY VIRUS; VIRION; VIRUS ENTRY; VIRUS REPLICATION; CD4+ T LYMPHOCYTE; GENE SILENCING; GENETICS; HELA CELL; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; METABOLISM; PHYSIOLOGY; VIROLOGY;

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 2; SIMIAE; SIMIAN IMMUNODEFICIENCY VIRUS;

CD4-POSITIVE T-LYMPHOCYTES; CULLIN PROTEINS; DNA-BINDING PROTEINS; GENE KNOCKDOWN TECHNIQUES; GENE SILENCING; HELA CELLS; HIV INFECTIONS; HIV-2; HUMANS; MACROPHAGES; SIMIAN IMMUNODEFICIENCY VIRUS; UBIQUITIN-PROTEIN LIGASES; VIRAL REGULATORY AND ACCESSORY PROTEINS; VIRUS REPLICATION;

EID: 65349104493     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.00187-09     Document Type: Article

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