Enhanced Akt Signaling Is an Early Pro-survival Response That Reflects N-Methyl-D-aspartate Receptor Activation in Huntington's Disease Knock-in Striatal Cells

Journal of Biological Chemistry

Volumn 278, Issue 50, 2003, Pages 50514-50522

  Gines, Silvia ^a   Ivanova, Elena ^a   Seong, Ihn Sik ^a   Saura, Carlos A ^b   MacDonald, Marcy E ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; DISEASES; PATHOLOGY; TOXICITY;

MUTANTS;

BIOCHEMISTRY;

2 MORPHOLINO 8 PHENYLCHROMONE; BETA CATENIN; CAGA PROTEIN; CYCLINE; DIZOCILPINE; HUNTINGTIN; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PROTEIN KINASE B; TRANSCRIPTION FACTOR;

ACUTE TOXICITY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTOSOMAL DOMINANT INHERITANCE; CALCIUM TRANSPORT; CELL SURVIVAL; CONTROLLED STUDY; ENZYME SPECIFICITY; FEMALE; GENE TARGETING; HUNTINGTON CHOREA; MALE; MOUSE; NEUROPROTECTION; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; SAMPLING; STRIATE CORTEX; TANDEM REPEAT;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ALLELES; ANIMALS; BETA CATENIN; CELL MEMBRANE; CELLS, CULTURED; CHROMONES; CORPUS STRIATUM; CYCLIN D1; CYTOSKELETAL PROTEINS; CYTOSOL; ENZYME ACTIVATION; GLYCOGEN SYNTHASE KINASE 3; HUNTINGTON DISEASE; IMMUNOBLOTTING; MICE; MICE, TRANSGENIC; MODELS, BIOLOGICAL; MORPHOLINES; MUTATION; NEURONS; PHENOTYPE; PHOSPHORYLATION; PRECIPITIN TESTS; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTORS, N-METHYL-D-ASPARTATE; SERINE; SIGNAL TRANSDUCTION; TRANS-ACTIVATORS; TRANSCRIPTION, GENETIC;

ANIMALIA;

EID: 0346749473     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M309348200     Document Type: Article

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