8OHdG as a marker for Huntington disease progression

Neurobiology of Disease

Volumn 46, Issue 3, 2012, Pages 625-634

  Long, Jeffrey D ^a,c   Matson, Wayne R ^b   Juhl, Andrew R ^c   Leavitt, Blair R ^d   Paulsen, Jane ^af   Wassink, Thomas ^c   Cross, Stephen ^c   Doucette, Nicholas ^c   Kimble, Mycah ^c   Ryan, Patricia ^c   Wood, Jessica ^c   Epping, Eric A ^c,af   Beglinger, Leigh J ^c   Chiu, Edmond ^e   Yastrubetskaya, Olga ^e   Preston, Joy ^e   Goh, Anita ^e   Fonseka, Chathushka ^e   Ronsisvalle, Liz ^e   Chua, Phyllis ^e   Komiti, Angela ^e   Raymond, Lynn ^d   Santos, Rachelle Dar ^d   Decolongon, Joji ^d   Rosenblatt, Adam ^f   Ross, Christopher A ^f   Shpritz, Barnett ^f   Welsh, Claire ^f   Mallonee, William M ^g   Suter, Greg ^g   Addison, Judy ^g   Samii, Ali ^h   Macaraeg, Alma ^h   Jones, Randi ⁱ   Wood Siverio, Cathy ⁱ   Factor, Stewart A ⁱ   Testa, Claudia ⁱ   Barker, Roger A ^j   Mason, Sarah ^j   Goodman, Anna ^j   Swain, Rachel ^j   Dipietro, Anna ^j   McCusker, Elizabeth ^k   Griffith, Jane ^k   Loy, Clement ^k   Gunn, David ^k   Stewart, Linda ^k   Landwehrmeyer, Bernhard G ^l   Orth, Michael ^l   Süβmuth, Sigurd ^l   Barth, Katrin ^l   Trautmann, Sonja ^l   Quaid, Kimberly ^m   Wesson, Melissa ^m   Wojcieszek, Joanne ^m   Guttman, Mark ⁿ   Sheinberg, Alanna ⁿ   Karmalkar, Irita ⁿ   Perlman, Susan ^o   Johnson, Arik ^o   Geschwind, Michael ^p   Gooblar, Jon ^p   Kang, Gail ^p   Warner, Tom ^q   Burrows, Maggie ^q   Novak, Marianne ^q   Andrews, Thomasin ^q   Rosser, Elisabeth ^q   Tabrizi, Sarah ^q   Rosser, Anne ^r   Price, Kathy ^r   Hunt, Sarah ^r   Marshall, Frederick ^s   Chesire, Amy ^s   Wodarski, Mary ^s   Hickey, Charlyne ^s   Suchowersky, Oksana ^t   Furtado, Sarah ^t   Klimek, Mary Lou ^t   Panegyres, Peter ^u   Vuletich, Elizabeth ^u   Andrew, Steve ^u   Zombor, Rachel ^u   Perlmutter, Joel ^v   Barton, Stacey ^v   Schmidt, Amy ^v   Miedzybrodzka, Zosia ^w,ar   Simpson, Sheila A ^w   Rae, Daniela ^w   D'alessandro, Mariella ^w   Craufurd, David ^x   Fullam, Ruth ^x   Howard, Elizabeth ^x   Mazzoni, Pietro ^y   Marder, Karen ^y,bf   Wasserman, Paula ^y   Kumar, Rajeev ^z   Erickson, Diane ^z   Wheelock, Vicki ^aa   Tempkin, Terry ^aa   Mans, Nicole ^aa   Baynes, Kathleen ^aa   Jankovic, Joseph ^ab   Hunter, Christine ^ab   Ondo, William ^ab   de Yebenes, Justo Garcia ^ac   Garde, Monica Bascunana ^ac   Fatas, Marta ^ac   Martinez Descales, Asuncion ^ac   Martin, Wayne ^ad   King, Pamela ^ad   Sran, Satwinder ^ad   Ahmed, Anwar ^ae   Rao, Steve ^ae   Reece, Christine ^ae   Zimbelman, Jan ^ae   Bea, Alexandra ^ae   Newman, Emily ^ae   Bura, Alex ^ae   Johnson, Hans ^c,af   Smith, Megan M ^c,af   Williams, Janet ^c,af   Beglinger, Leigh ^c,af   Mills, James ^c,d,af   Aylward, Elizabeth ^ag,bc   Biglan, Kevin ^s   Macdonald, Marcy ^ah   Nance, Martha ^ai,bk,bl   Erwin, Cheryl ^aj,bk,bl   Hayden, Michael ^d   Didonato, Stefano ^ak   Evans, Ken ^al   Peterson, Asa ^am   Borowsky, Beth ^an   Juhl, Andrew ^c,d   Weir, David ^d   Vonsattell, Jean Paul ^y   Moskowitz, Carol ^y   Leserman, Anne ^c   Schaul, Lynn ^c   Vik, Stacie ^c   Harrington, Deborah ^ao   Castillo, Gabriel ^ao   Morison, Jessica ^ao   Reed, Jason ^ao   Diaz, Michael ^ap   Dobbins, Ian ^ap   Hershey, Tamara ^ap   Foster, Erin ^ap   Moore, Deborah ^ap   Westervelt, Holly ^aq   Davis, Jennifer ^aq   Tremont, Geoff ^aq   Moser, David ^c   Rowe, Kelly ^c   Theriault, Danielle ^c   Gehl, Carissa ^b   Matheson, Kirsty ^ar   Siedlecki, Karen ^as   Van Walsem, Marleen ^bg   Bonner, Susan ^at   Elias, Greg ^at   Faust, Melanie ^at   Borowski, Beth ^bg   Carlozzi, Noelle ^au   Duff, Kevin ^av   Georgiou Karistianis, Nellie ^e   Stout, Julie ^aw   Lange, Herwig ^bg   Papp, Kate ^ax   Ro, Eunyoe ^c   Clark, Lee Anna ^c   Downing, Nancy ^c   Laing, Joan ^c   Rees, Kristine ^c   Ready, Rebecca ^ay   Vaccarino, Anthony ^al   Farias, Sarah ^aa   Gusella, Jim ^ah   Myers, Rick ^ah   Wang, Kai ^c   Ross, Christopher ^f   Pierson, Ron ^c   Jones, Kathy ^c   Marietta, Jacquie ^c   McDowell, William ^c   Harris, Greg ^c   Kim, Eun Young ^c   Ashburner, John ^az   Potkin, Steve ^ba   Toga, Arthur ^bb   Axelson, Eric ^c   Miller, Michael ^f   Reading, Sarah ^f   Beg, Mirza Faisal ^bd   Magnotta, Vincent A ^c   Helmer, Karl ^ah   Lim, Kelvin ^l   Lowe, Mark ^ae   Mori, Sasumu ^f   Song, Allen ^be   Turner, Jessica ^ba   Beall, Erik ^ae   Koenig, Katherine ^ae   Phillips, Michael ^ae   Bryant, April ^c   Corey Bloom, Jody ^ao   Reilmann, Ralf ^bg   Unds, Zerka ^bg   Fiedorowicz, Jess ^c   Robinson, Robert ^c   Ruggle, Adam ^c   Liu, Dawei ^c   Anderson, Karen ^bh   Groves, Mark ^bf   Rickards, Hugh ^bi   van Duijn, Eric ^bj   Antonijevic, Irina ^bg   Giuliano, Joseph ^bg   Lu, Wenjing ^c   Lourens, Spencer ^c   Zhang, Ying ^c   Thumma, Kelli ^c   Waterman, Elijah ^c   Hinkel, Jeremy ^c   Hughes, Lisa ^aj   Connell, R J ^c   Pease, Karen ^c   Rogers, Ben ^c   Smith, Jim ^c   Wu, Shuhua ^c   Zschiegner, Roland ^c   Carney, Erin ^c   McKirgan, Bill ^c   Scully, Mark ^c   Wyse, Ryan ^c   Bockholt, Jeremy ^bg   Werling Witkoske, Chris ^c   Anderson, Karla ^c   Rapp, Jennifer ^c   Dudler, Ann ^c   Schumacher, Jamy ^c   Thompson, Sean ^c   Davis, Leann ^c   Henneberry, Machelle ^c   Ennis, Greg ^c   Blanchard, Steve ^c   Montross, Kelsey ^c   Danzer, Phil ^c   more..

^a UNIVERSITY OF IOWA   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c UNIVERSITY OF IOWA   (United States)

^d UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^e UNIVERSITY OF MELBOURNE   (Australia)

^f JOHNS HOPKINS UNIVERSITY   (United States)

^g Hereditary Neurological Disease Centre   (United States)

^h VA PUGET SOUND HEALTH CARE SYSTEM   (United States)

ⁱ EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^j UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^k WESTMEAD HOSPITAL   (Australia)

^l UNIVERSITY OF ULM   (Germany)

^m INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

ⁿ UNIVERSITY OF TORONTO   (Canada)

^o UCLA MEDICAL CENTER   (United States)

^p UNIVERSITY OF CALIFORNIA   (United States)

^q NATIONAL HOSPITAL FOR NEUROLOGY AND NEUROSURGERY   (United Kingdom)

^r CARDIFF UNIVERSITY   (United Kingdom)

^s UNIVERSITY OF ROCHESTER   (United States)

^t UNIVERSITY OF CALGARY   (Canada)

^u Graylands Selby Lemnos and Special Care Health Services   (Australia)

^v WASHINGTON UNIVERSITY   (United States)

^w Clinical Genetics Centre   (United Kingdom)

^x UNIVERSITY OF MANCHESTER   (United Kingdom)

^y NewYork Presbyterian Hospital   (United States)

^z Clinical Genetics Centre ^*  (United States)

^aa UNIVERSITY OF CALIFORNIA   (United States)

^ab BAYLOR COLLEGE OF MEDICINE   (United States)

^ac HOSPITAL RAMÓN Y CAJAL   (Spain)

^ad UNIVERSITY OF ALBERTA   (Canada)

^ae LERNER RESEARCH INSTITUTE   (United States)

^af UNIVERSITY OF IOWA HOSPITALS AND CLINICS   (United States)

^ag SEATTLE CHILDREN S RESEARCH INSTITUTE   (United States)

^ah MASSACHUSETTS GENERAL HOSPITAL   (United States)

^ai HENNEPIN COUNTY MEDICAL CENTER   (United States)

^aj UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

^ak Neurological Institute C Besta   (Italy)

^al Ontario Cancer Biomarker Network   (Canada)

^am LUND UNIVERSITY   (Sweden)

^an CHDI   (United States)

^ao UNIVERSITY OF CALIFORNIA   (United States)

^ap Washington University Cognitive Science Battery Development   (United States)

^aq BROWN UNIVERSITY   (United States)

^ar UNIVERSITY OF ABERDEEN   (United Kingdom)

^as FORDHAM UNIVERSITY   (United States)

^at RHODE ISLAND HOSPITAL   (United States)

^au UNIVERSITY OF MICHIGAN   (United States)

^av UNIVERSITY OF UTAH   (United States)

^aw MONASH UNIVERSITY   (Australia)

^ax UNIVERSITY OF CONNECTICUT   (United States)

^ay UNIVERSITY OF MASSACHUSETTS   (United States)

^az Functional Imaging Laboratory   (United Kingdom)

^ba UNIVERSITY OF CALIFORNIA   (United States)

^bb UNIVERSITY OF CALIFORNIA   (United States)

^bc SEATTLE CHILDREN S RESEARCH INSTITUTE   (United States)

^bd SIMON FRASER UNIVERSITY   (Canada)

^be DUKE UNIVERSITY   (United States)

^bf Och Spine at New York Presbyterian Hospitals   (United States)

^bg Simon Fraser University ^*

^bh UNIVERSITY OF MARYLAND   (United States)

^bi QUEEN ELIZABETH PSYCHIATRIC HOSPITAL   (United Kingdom)

^bj LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^bk UNIVERSITY OF MINNESOTA   (United States)

^bl Humanities and the Human Spirit   (United States)

more..

Author keywords

8OHdG; Biomarker; Huntington disease; Mitochondrial dysfunction; Oxidative stress; PREDICT HD

Indexed keywords

8 HYDROXYDEOXYGUANOSINE;

ARTICLE; BLOOD ANALYSIS; CONTROLLED STUDY; DISEASE COURSE; FEMALE; HUMAN; HUNTINGTON CHOREA; LIQUID CHROMATOGRAPHY; MALE; MASS SPECTROMETRY; PRIORITY JOURNAL; SENSITIVITY AND SPECIFICITY;

EID: 84860835246     PISSN: 09699961     EISSN: 1095953X     Source Type: Journal    
DOI: 10.1016/j.nbd.2012.02.012     Document Type: Article

References (37)

1. Akaike H. Information theory as an extension of the maximum likelihood principle. Second International Symposium on Information Theory 1973, 267-281. Akademia Kiado, Budapest, Hungary. B.N. Petrov, F. Csaki (Eds.).
2. Akaike H. A new look at the statistical model identification. IEEE Trans. Autom. Control 1974, AC-19:716-723.
3. Anderson D.R. Model-based Inference in the Life Sciences: A Primer on Evidence 2008, Springer, New York; London.
4. Beglinger L.J., Paulsen J.S., Watson D.B., Wang C., Duff K., Langbehn D.R., et al. Obsessive and compulsive symptoms in prediagnosed Huntington's disease. J. Clin. Psychiatry 2008, 69:1758-1765.
5. Biglan K.M., Ross C.A., Langbehn D.R., Aylward E.H., Stout J.C., Queller S., et al. Motor abnormalities in premanifest persons with Huntington's disease: the PREDICT-HD study. Mov. Disord. 2009, 24:1763-1772.
6. Bogdanov M.B., Beal M.F., McCabe D.R., Griffin R.M., Matson W.R. A carbon column-based liquid chromatography electrochemical approach to routine 8-hydroxy-2'-deoxyguanosine measurements in urine and other biologic matrices: a one-year evaluation of methods. Free Radic. Biol. Med. 1999, 27:647-666.
7. Bogdanov M.B., Andreassen O.A., Dedeoglu A., Ferrante R.J., Beal M.F. Increased oxidative damage to DNA in a transgenic mouse model of Huntington's disease. J. Neurochem. 2001, 79:1246-1249.
8. Browne S.E., Beal M.F. Oxidative damage in Huntington's disease pathogenesis. Antioxid. Redox Signal. 2006, 8:2061-2073.
9. Browne S.E., Bowling A.C., MacGarvey U., Baik M.J., Berger S.C., Muqit M.M., et al. Oxidative damage and metabolic dysfunction in Huntington's disease: selective vulnerability of the basal ganglia. Ann. Neurol. 1997, 41:646-653.
10. Burnham K.P., Anderson D.R. Model Selection and Multimodel Inference 2002, Springer, New York.
11. Chen C.M., Wu Y.R., Cheng M.L., Liu J.L., Lee Y.M., Lee P.W., et al. Increased oxidative damage and mitochondrial abnormalities in the peripheral blood of Huntington's disease patients. Biochem. Biophys. Res. Commun. 2007, 359:335-340.
12. Duff K., Paulsen J.S., Beglinger L.J., Langbehn D.R., Stout J.C. Psychiatric symptoms in Huntington's disease before diagnosis: the PREDICT-HD study. Biol. Psychiatry 2007, 62:1341-1346.
13. Duff K., Paulsen J., Mills J., Beglinger L.J., Moser D.J., Smith M.M., et al. Mild cognitive impairment in prediagnosed Huntington disease. Neurology 2010, 75:500-507.
14. Hersch S.M., Gevorkian S., Marder K., Moskowitz C., Feigin A., Cox M., et al. Creatine in Huntington disease is safe, tolerable, bioavailable in brain and reduces serum 8OH2'dG. Neurology 2006, 66:250-252.
15. Hurvich C.M., Tsai C. Regression and time series model selection in small samples. Biometrika 1989, 76:297-307.
16. Kikuchi A., Takeda A., Onodera H., Kimpara T., Hisanaga K., Sato N., et al. Systemic increase of oxidative nucleic acid damage in Parkinson's disease and multiple system atrophy. Neurobiol. Dis. 2002, 9:244-248.
17. Klepac N., Relja M., Klepac R., Hecimovic S., Babic T., Trkulja V. Oxidative stress parameters in plasma of Huntington's disease patients, asymptomatic Huntington's disease gene carriers and healthy subjects: a cross-sectional study. J. Neurol. 2007, 254:1676-1683.
18. Langbehn D.R., Brinkman R.R., Falush D., Paulsen J.S., Hayden M.R. A new model for prediction of the age of onset and penetrance for Huntington's disease based on CAG length. Clin. Genet. 2004, 65:267-277.
19. Long J.D. Longitudinal Data Analysis for the Behavioral Sciences Using R 2012, Sage Publications, Inc., Thousand Oaks, CA.
20. Marnett L.J. Oxyradicals and DNA damage. Carcinogenesis 2000, 21:361-371.
21. Matson W.R., Langlais P., Volicer L., Gamache P.H., Bird E., Mark K.A. n-Electrode three-dimensional liquid chromatography with electrochemical detection for determination of neurotransmitters. Clin. Chem. 1984, 30:1477-1488.
22. Matson W.R., Gamache P.G., Beal M.F., Bird E.D. EC array sensor concepts and data. Life Sci. 1987, 41:905-908.
23. Nopoulos P.C., Aylward E.H., Ross C.A., Mills J.A., Langbehn D.R., Johnson H.J., et al. Smaller intracranial volume in prodromal Huntington's disease: evidence for abnormal neurodevelopment. Brain 2011, 134:137-142.
24. Paulsen J.S., Hayden M., Stout J.C., Langbehn D.R., Aylward E., Ross C.A., et al. Preparing for preventive clinical trials: the Predict-HD study. Arch. Neurol. 2006, 63:883-890.
25. Paulsen J.S., Langbehn D.R., Stout J.C., Aylward E., Ross C.A., Nance M., et al. Detection of Huntington's disease decades before diagnosis: the Predict-HD study. J. Neurol. Neurosurg. Psychiatry 2008, 79:874-880.
26. Paulsen J.S., Nopoulos P.C., Aylward E., Ross C.A., Johnson H., Magnotta V.A., et al. Striatal and white matter predictors of estimated diagnosis for Huntington disease. Brain Res. Bull. 2010, 82:201-207.
27. Paulsen J.S., Wang C., Duff K., Barker R., Nance M., Beglinger L., et al. Challenges assessing clinical endpoints in early Huntington disease. Mov. Disord. 2010, 25:2595-2603.
28. Polidori M.C., Mecocci P., Browne S.E., Senin U., Beal M.F. Oxidative damage to mitochondrial DNA in Huntington's disease parietal cortex. Neurosci. Lett. 1999, 272:53-56.
29. Ross C.A., Tabrizi S.J. Huntington's disease: from molecular pathogenesis to clinical treatment. Lancet Neurol. 2011, 10:83-98.
30. Sayre L.M., Smith M.A., Perry G. Chemistry and biochemistry of oxidative stress in neurodegenerative disease. Curr. Med. Chem. 2001, 8:721-738.
31. Sorolla M.A., Reverter-Branchat G., Tamarit J., Ferrer I., Ros J., Cabiscol E. Proteomic and oxidative stress analysis in human brain samples of Huntington disease. Free Radic. Biol. Med. 2008, 45:667-678.
32. Stout J.C., Paulsen J.S., Queller S., Solomon A.C., Whitlock K.B., Campbell J.C., et al. Neurocognitive signs in prodromal Huntington disease. Neuropsychology 2011, 25:1-14.
33. Tabrizi S.J., Langbehn D.R., Leavitt B.R., Roos R.A., Durr A., Craufurd D., et al. Biological and clinical manifestations of Huntington's disease in the longitudinal TRACK-HD study: cross-sectional analysis of baseline data. Lancet Neurol. 2009, 8:791-801.
34. A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. Cell 1993, 72:971-983. The Huntington's Disease Collaborative Research Group.
35. Valavanidis A., Vlachogianni T., Fiotakis C. 8-hydroxy-2' -deoxyguanosine (8-OHdG): a critical biomarker of oxidative stress and carcinogenesis. J. Environ. Sci. Health C 2009, 27:120-139.
36. Verbeke G., Molenberghs G. Linear Mixed Models for Longitudinal Data 2000, Springer, New York.
37. Zhang Y., Long J.D., Mills J., Warner J.H., Lu W., Paulsen J.S., et al. Indexing disease progression at study entry with individuals at-risk for Huntington disease. Am. J. Med. Genet. B Neuropsychiatr. Genet. 2011, 156:751-763.