Proteasome inhibition increases HuR level, restores heat-inducible HSP72 expression and thermotolerance in WI-38 senescent human fibroblasts

Experimental Gerontology

Volumn 39, Issue 3, 2004, Pages 423-432

  Bonelli, Mara A ^a   Alfieri, Roberta R ^a   Desenzani, Silvia ^a   Petronini, Pier Giorgio ^a   Borghetti, Angelo F ^a  

^a UNIVERSITY OF PARMA   (Italy)

Author keywords

Aging; Heat shock; HSP72; HSP72 mRNA; Human fibroblast; HuR; MG132; mRNA stability; Proteasome; Thermotolerance

Indexed keywords

BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; HEAT SHOCK PROTEIN 72; HUR PROTEIN; MESSENGER RNA; PROTEASOME; RNA BINDING PROTEIN;

ARTICLE; CELL AGING; CELL LEVEL; CONTROLLED STUDY; CORRELATION ANALYSIS; CYTOPLASM; ENZYME INHIBITION; FIBROBLAST; HEAT SHOCK RESPONSE; HEAT TOLERANCE; HUMAN; HUMAN CELL; NUCLEOCYTOPLASMIC TRANSPORT; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN SYNTHESIS; RNA DEGRADATION; RNA TRANSLATION; RNA TRANSPORT; SENESCENCE;

EID: 1342265394     PISSN: 05315565     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.exger.2003.12.004     Document Type: Article

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