Polysome Profiling in Liver Identifies Dynamic Regulation of Endoplasmic Reticulum Translatome by Obesity and Fasting

PLoS Genetics

Volumn 8, Issue 8, 2012, Pages

  Fu, Suneng ^a   Fan, Jason ^a   Blanco, Joshua ^a   Gimenez Cassina, Alfredo ^b   Danial, Nika N ^b   Watkins, Steve M ^a   Hotamisligil, Gökhan S ^a,c  

^a HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^b DANA FARBER CANCER INSTITUTE   (United States)

^c BROAD INSTITUTE OF MIT AND HARVARD   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; BILE ACID; GLUCOSE; MESSENGER RNA; SIRTUIN 3; SUCCINATE DEHYDROGENASE; TRICARBOXYLIC ACID; CYP7B1 PROTEIN, MOUSE; STEROID MONOOXYGENASE;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BILE ACID BLOOD LEVEL; BILE ACID METABOLISM; CHOLESTASIS; CONTROLLED STUDY; CYP7B1 GENE; DIET RESTRICTION; DISEASE ASSOCIATION; DOWN REGULATION; ENDOPLASMIC RETICULUM; FATTY LIVER; GENE; GENE EXPRESSION REGULATION; GENE OVEREXPRESSION; GENETIC PROCEDURES; GLUCONEOGENESIS; GLUCOSE BLOOD LEVEL; GLUCOSE HOMEOSTASIS; HUMAN; MALE; METABOLIC REGULATION; MOLECULAR DYNAMICS; MOUSE; NONHUMAN; OBESITY; OXIDATIVE PHOSPHORYLATION; PATHOGENESIS; POLYSOME PROFILING; PROTEIN DEGRADATION; PROTEIN SYNTHESIS REGULATION; RNA SPLICING; RNA TRANSLATION; SLCO1A1 GENE; TRANSLATION REGULATION; TRANSLATOME; UPREGULATION; ANIMAL; GENETICS; GERMFREE ANIMAL; LIVER; METABOLISM; MOUSE MUTANT; PATHOLOGY; POLYSOME; PROTEIN SYNTHESIS;

MUS;

ANIMALS; BILE ACIDS AND SALTS; CHOLESTASIS; ENDOPLASMIC RETICULUM; FASTING; FATTY LIVER; GLUCOSE; LIVER; MALE; MICE; MICE, OBESE; OBESITY; POLYRIBOSOMES; PROTEIN BIOSYNTHESIS; SPECIFIC PATHOGEN-FREE ORGANISMS; STEROID HYDROXYLASES;

EID: 84866184236     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1002902     Document Type: Article

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