Proteasomal degradation of the FoxO1 transcriptional regulator in cells transformed by the P3k and Akt oncoproteins

Proceedings of the National Academy of Sciences of the United States of America

Volumn 101, Issue 37, 2004, Pages 13613-13617

  Aoki, Masahiro ^b   Jiang, Hao ^a   Vogt, Peter K ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b KYOTO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Oncogenic transformation; Phosphoinositide 3 kinase; Transcriptional repression

Indexed keywords

INSECT PROTEIN; LACTACYSTIN; ONCOPROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PLATELET DERIVED GROWTH FACTOR; PROTEASOME; PROTEASOME INHIBITOR; PROTEIN INHIBITOR; PROTEIN KINASE B; TRANSCRIPTION FACTOR FKHR;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CARCINOGENICITY; CELL TRANSFORMATION; CONTROLLED STUDY; DOWN REGULATION; DROSOPHILA; EMBRYO; EMBRYO CELL; ENZYME ACTIVE SITE; ENZYME BLOOD LEVEL; ENZYME INHIBITION; FIBROBLAST; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN EXPRESSION; SEQUENCE HOMOLOGY; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION; TRANSCRIPTION TERMINATION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; CELL DIVISION; CELL LINE, TRANSFORMED; CELL TRANSFORMATION, NEOPLASTIC; CHICKENS; CYSTEINE ENDOPEPTIDASES; DNA-BINDING PROTEINS; DOWN-REGULATION; FORKHEAD TRANSCRIPTION FACTORS; GENE EXPRESSION; HUMANS; MULTIENZYME COMPLEXES; ONCOGENE PROTEINS; PHOSPHORYLATION; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; TRANSCRIPTION FACTORS;

ANIMALIA; GALLUS GALLUS; INSECTA;

EID: 4544312844     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0405454101     Document Type: Article

References (44)

1. Vivanco, I. & Sawyers, C. L. (2002) Nat. Rev. Cancer 2, 489-501.
2. Samuels, Y., Wang, Z., Bardelli, A., Silliman, N., Ptak, J., Szabo, S., Yan, H., Gazdar, A., Powell, S. M., Riggins, G. J., et al. (2004) Science 304, 554.
3. Chang, H. W., Aoki, M., Fruman, D., Auger, K. R., Bellacosa, A., Tsichlis, P. N., Cantley, L. C., Roberts, T. M. & Vogt, P. K. (1997) Science 276, 1848-1850.
4. Aoki, M., Schetter, C., Himly, M., Batista, O., Chang, H. W. & Vogt, P. K. (2000) J. Biol. Chem. 275, 6267-6275.
5. Aoki, M., Batista, O., Bellacosa, A., Tsichlis, P. & Vogt, P. K. (1998) Proc. Natl. Acad. Sci. USA 95, 14950-14955.
6. Alessi, D. R. & Cohen, P. (1998) Curr. Opin. Genet. Dev. 8, 55-62.
7. Chan, T. O., Rittenhouse, S. E. & Tsichlis, P. N. (1999) Annu. Rev. Biochem. 68, 965-1014.
8. Datta, S. R., Brunet, A. & Greenberg, M. E. (1999) Genes Dev. 13, 2905-2927.
9. Downward, J. (1998) Curr. Opin. Cell Biol. 10, 262-267.
10. Lawlor, M. A. & Alessi, D. R. (2001) J. Cell Sci. 114, 2903-2910.
11. Aoki, M. & Vogt, P. K. (2004) Curr. Top. Microbiol. Immunol. 279, 321-338.
12. Weigel, D. & Jackle, H. (1990) Cell 63, 455-456.
13. Kaestner, K. H., Knochel, W. & Martinez, D. E. (2000) Genes Dev. 14, 142-146.
14. Accili, D. & Arden, K. C. (2004) Cell 117, 421-426.
15. Brunet, A., Bonni, A., Zigmond, M. J., Lin, M. Z., Juo, P., Hu, L. S., Anderson, M. J., Arden, K. C., Blenis, J. & Greenberg, M. E. (1999) Cell 96, 857-868.
16. Brunet, A., Kanai, F., Stehn, J., Xu, J., Sarbassova, D., Frangioni, J. V., Dalal, S. N., DeCaprio, J. A., Greenberg, M. E. & Yaffe, M. B. (2002) J. Cell Biol. 156, 817-828.
17. Cahill, C. M., Tzivion, G., Nasrin, N., Ogg, S., Dore, J., Ruvkun, G. & Alexander-Bridges, M. (2001) J. Biol. Chem. 276, 13402-13410.
18. Biggs, W. H., III, Meisenhelder, J., Hunter, T., Cavenee, W. K. & Arden, K. C. (1999) Proc. Natl. Acad. Sci. USA 96, 7421-7426.
19. Kops, G. J., de Ruiter, N. D., De Vries-Smits, A. M., Powell, D. R., Bos, J. L. & Burgering, B. M. (1999) Nature 398, 630-634.
20. Matsuzaki, H., Daitoku, H., Hatta, M., Tanaka, K. & Fukamizu, A. (2003) Proc. Natl. Acad. Sci. USA 100, 11285-11290.
21. Plas, D. R. & Thompson, C. B. (2003) J. Biol. Chem. 278, 12361-12366.
22. Seoane, J., Le, H. V., Shen, L., Anderson, S. A. & Massague, J. (2004) Cell 117, 211-223.
23. Sonderegger, C. K. & Vogt, P. K. (2003) Oncogene 22, 1749-1757.
24. Li, J., Thurm, H., Chang, H. W., Iacovoni, J. S. & Vogt, P. K. (1997) Proc. Natl. Acad. Sci. USA 94, 10885-10888.
25. Li, J., Chang, H. W., Lai, E., Parker, E. J. & Vogt, P. K. (1995) Cancer Res. 55, 5540-5544.
26. Tan, K., Shaw, A. L., Madsen, B., Jensen, K., Taylor-Papadimitriou, J. & Freemont, P. S. (2003) J. Biol. Chem. 278, 20507-20513.
27. Yao, J., Lai, E. & Stifani, S. (2001) Mol. Cell. Biol. 21, 1962-1972.
28. Vogt, P. K. (1969) in Fundamental Techniques in Virology, eds. Habel, K. & Salzman, N. P. (Academic, New York), pp. 316-326.
29. Hughes, S. H., Greenhouse, J. J., Petropoulos, C. J. & Sutrave, P. (1987) J. Virol. 61, 3004-3012.
30. Kempf, B. E. & Vogt, P. K. (1999) Cell Growth Differ. 10, 813-818.
31. Kunkel, T. A., Bebenek, K. & McClary, J. (1991) Methods Enzymol. 204, 125-139.
32. Sonderegger, C. K., Narisawa-Saito, M. & Vogt, P. K. (2003) Oncogene 22, 1908-1915.
33. Leenders, H., Whiffield, S., Benoist, C. & Mathis, D. (2000) Eur. J. Immunol. 30, 2980-2990.
34. Nakae, J., Kitamura, T., Silver, D. L. & Accili, D. (2001) J. Clin. Invest. 108, 1359-1367.
35. Li, J. & Vogt, P. K. (1993) Proc. Natl. Acad. Sci. USA 90, 4490-4494.
36. Tao, W. & Lai, E. (1992) Neuron 8, 957-966.
37. Chang, H. W., Li, J., Kretzschmar, D. & Vogt, P. K. (1995) Proc. Natl. Acad. Sci. USA 92, 447-451.
38. Xuan, S., Baptista, C. A., Balas, G., Tao, W., Soares, V. C. & Lai, E. (1995) Neuron 14, 1141-1152.
39. Hanashima, C., Shen, L., Li, S. C. & Lai, E. (2002) J. Neurosci. 22, 6526-6536.
40. Hanashima, C., Li, S. C., Shen, L., Lai, E. & Fishell, G. (2004) Science 303, 56-59.
41. Ahlgren, S., Vogt, P. K. & Bronner-Fraser, M. (2003) J. Neurobiol. 57, 337-349.
42. Furuyama, T., Nakazawa, T., Nakano, I. & Mori, N. (2000) Biochem. J. 349, 629-634.
43. Bouchard, C., Marquardt, J., Bras, A., Medema, R. H., Eilers, M. (2004) EMBO J. 23, 2830-2840.
44. Aoki, M., Blazek, E. & Vogt, P. K. (2001) Proc. Natl. Acad. Sci. USA 98, 136-141.