HIPK2 kinase activity depends on cis-autophosphorylation of its activation loop

Journal of Molecular Cell Biology

Volumn 5, Issue 1, 2013, Pages 27-38

  Saul, Vera V ^a   De La Vega, Laureano ^a   Milanovic, Maja ^a   Krüger, Marcus ^b   Braun, Thomas ^b   Fritz Wolf, Karin ^a,c   Becker, Katja ^a   Schmitz, M Lienhard ^a  

^a JUSTUS LIEBIG UNIVERSITY   (Germany)

^b MAX PLANCK INSTITUTE FOR HEART AND LUNG RESEARCH   (Germany)

^c MAX PLANCK INSTITUTE FOR MEDICAL RESEARCH   (Germany)

Author keywords

activation loop; autophosphorylation; gene expression; HIPK2; protein kinase

Indexed keywords

CALYCULIN A; EARLY GROWTH RESPONSE FACTOR 1; GLUTATHIONE TRANSFERASE; HOMEODOMAIN INTERACTING PROTEIN KINASE 2; NUCLEOPLASMIN; PEPTIDYLPROLYL ISOMERASE PIN1;

ARTICLE; AUTOPHOSPHORYLATION; BINDING AFFINITY; CELL PROLIFERATION; ENZYME ACTIVITY; GENE EXPRESSION; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; IN VITRO STUDY; MOLECULAR DOCKING; NONHUMAN; POINT MUTATION; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION;

AMINO ACID SEQUENCE; CARRIER PROTEINS; CELL LINE; ENZYME ACTIVATION; HUMANS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN-SERINE-THREONINE KINASES; SEQUENCE ALIGNMENT; SUBSTRATE SPECIFICITY;

EID: 84874332563     PISSN: 16742788     EISSN: 17594685     Source Type: Journal    
DOI: 10.1093/jmcb/mjs053     Document Type: Article

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