Nox1 is involved in p53 deacetylation and suppression of its transcriptional activity and apoptosis

Free Radical Biology and Medicine

Volumn 48, Issue 10, 2010, Pages 1338-1346

  Puca, Rosa ^a,b   Nardinocchi, Lavinia ^a,b   Starace, Giuseppe ^a,c   Rechavi, Gideon ^d   Sacchi, Ada ^a   Givol, David ^e   D'Orazi, Gabriella ^a,b  

^a REGINA ELENA NATIONAL CANCER INSTITUTE   (Italy)

^b UNIVERSITY OF CHIETI   (Italy)

^c CNR   (Italy)

^d SHEBA MEDICAL CENTER   (Israel)

^e WEIZMANN INSTITUTE OF SCIENCE   (Israel)

Author keywords

Free radicals; HIPK2; P53 lysine 382 acetylation; P53 transcriptional activity; Reactive oxygen species; SIRT1

Indexed keywords

HOMEODOMAIN INTERACTING PROTEIN KINASE 2; NICOTINAMIDE; PROTEIN P53; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 1; SIRTUIN 1; SMALL INTERFERING RNA;

APOPTOSIS; ARTICLE; CONTROLLED STUDY; DEACETYLATION; DOWN REGULATION; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN TARGETING; TRANSCRIPTION REGULATION; UPREGULATION;

ACETYLATION; APOPTOSIS; BREAST NEOPLASMS; CARCINOMA; CARRIER PROTEINS; CELL LINE, TUMOR; CLONING, MOLECULAR; COLONIC NEOPLASMS; FEMALE; HUMANS; LUNG NEOPLASMS; MUTANT PROTEINS; NADPH OXIDASE; NIACINAMIDE; PROTEIN-SERINE-THREONINE KINASES; RNA, SMALL INTERFERING; SIRTUIN 1; TRANSCRIPTIONAL ACTIVATION; TUMOR SUPPRESSOR PROTEIN P53;

EID: 77951938173     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2010.02.015     Document Type: Article

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