-
1
-
-
77952566949
-
Mechanisms, regulation and consequences of protein SUMOylation
-
Wilkinson K.A., Henley J.M. Mechanisms, regulation and consequences of protein SUMOylation. Biochem. J. 2010, 428:133-145.
-
(2010)
Biochem. J.
, vol.428
, pp. 133-145
-
-
Wilkinson, K.A.1
Henley, J.M.2
-
2
-
-
68049103216
-
An additional role for SUMO in ubiquitin-mediated proteolysis
-
Geoffroy M.C., Hay R.T. An additional role for SUMO in ubiquitin-mediated proteolysis. Nat. Rev. Mol. Cell Biol. 2009, 10:564-568.
-
(2009)
Nat. Rev. Mol. Cell Biol.
, vol.10
, pp. 564-568
-
-
Geoffroy, M.C.1
Hay, R.T.2
-
3
-
-
72949100510
-
Sumoylation: wrestling with filaments
-
Walker D. Sumoylation: wrestling with filaments. Nat. Rev. Mol. Cell Biol. 2010, 11:3.
-
(2010)
Nat. Rev. Mol. Cell Biol.
, vol.11
, pp. 3
-
-
Walker, D.1
-
4
-
-
33744940842
-
Specification of SUMO1- and SUMO2-interacting motifs
-
Hecker C.M., Rabiller M., Haglund K., Bayer P., Dikic I. Specification of SUMO1- and SUMO2-interacting motifs. J. Biol. Chem. 2006, 281:16117-16127.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 16117-16127
-
-
Hecker, C.M.1
Rabiller, M.2
Haglund, K.3
Bayer, P.4
Dikic, I.5
-
5
-
-
5144219680
-
Identification of a SUMO-binding motif that recognizes SUMO-modified proteins
-
Song J., Durrin L.K., Wilkinson T.A., Krontiris T.G., Chen Y. Identification of a SUMO-binding motif that recognizes SUMO-modified proteins. Proc. Natl Acad. Sci. USA 2004, 101:14373-14378.
-
(2004)
Proc. Natl Acad. Sci. USA
, vol.101
, pp. 14373-14378
-
-
Song, J.1
Durrin, L.K.2
Wilkinson, T.A.3
Krontiris, T.G.4
Chen, Y.5
-
6
-
-
34547683267
-
SUMO junction-what's your function? New insights through SUMO-interacting motifs
-
Kerscher O. SUMO junction-what's your function? New insights through SUMO-interacting motifs. EMBO Rep 2007, 8:550-555.
-
(2007)
EMBO Rep
, vol.8
, pp. 550-555
-
-
Kerscher, O.1
-
7
-
-
33846913249
-
HIPK2: a versatile switchboard regulating the transcription machinery and cell death
-
Calzado M.A., Renner F., Roscic A., Schmitz M.L. HIPK2: a versatile switchboard regulating the transcription machinery and cell death. Cell Cycle 2007, 6:139-143.
-
(2007)
Cell Cycle
, vol.6
, pp. 139-143
-
-
Calzado, M.A.1
Renner, F.2
Roscic, A.3
Schmitz, M.L.4
-
8
-
-
0345898928
-
Homeodomain-interacting protein kinases, a novel family of co-repressors for homeodomain transcription factors
-
Kim Y.H., Choi C.Y., Lee S.J., Conti M.A., Kim Y. Homeodomain-interacting protein kinases, a novel family of co-repressors for homeodomain transcription factors. J. Biol. Chem. 1998, 273:25875-25879.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 25875-25879
-
-
Kim, Y.H.1
Choi, C.Y.2
Lee, S.J.3
Conti, M.A.4
Kim, Y.5
-
9
-
-
34948910811
-
HIPK2: a multitalented partner for transcription factors in DNA damage response and development
-
Rinaldo C., Prodosmo A., Siepi F., Soddu S. HIPK2: a multitalented partner for transcription factors in DNA damage response and development. Biochem. Cell Biol. 2007, 85:411-418.
-
(2007)
Biochem. Cell Biol.
, vol.85
, pp. 411-418
-
-
Rinaldo, C.1
Prodosmo, A.2
Siepi, F.3
Soddu, S.4
-
10
-
-
10644290911
-
Axin stimulates p53 functions by activation of HIPK2 kinase through multimeric complex formation
-
Rui Y., Xu Z., Lin S., Li Q., Rui H., Luo W., Zhou H.M., Cheung P.Y., Wu Z., Ye Z., Li P., Han J., Lin S.C. Axin stimulates p53 functions by activation of HIPK2 kinase through multimeric complex formation. EMBO J. 2004, 23:4583-4594.
-
(2004)
EMBO J.
, vol.23
, pp. 4583-4594
-
-
Rui, Y.1
Xu, Z.2
Lin, S.3
Li, Q.4
Rui, H.5
Luo, W.6
Zhou, H.M.7
Cheung, P.Y.8
Wu, Z.9
Ye, Z.10
Li, P.11
Han, J.12
Lin, S.C.13
-
11
-
-
33646589651
-
Autoregulatory control of the p53 response by caspase-mediated processing of HIPK2
-
Gresko E., Roscic A., Ritterhoff S., Vichalkovski A., del Sal G., Schmitz M.L. Autoregulatory control of the p53 response by caspase-mediated processing of HIPK2. EMBO J. 2006, 25:1883-1894.
-
(2006)
EMBO J.
, vol.25
, pp. 1883-1894
-
-
Gresko, E.1
Roscic, A.2
Ritterhoff, S.3
Vichalkovski, A.4
del Sal, G.5
Schmitz, M.L.6
-
12
-
-
18244379872
-
Homeodomain-interacting protein kinase-2 phosphorylates p53 at Ser 46 and mediates apoptosis
-
D'Orazi G., Cecchinelli B., Bruno T., Manni I., Higashimoto Y., Saito S., Gostissa M., Coen S., Marchetti A., Del Sal G., Piaggio G., Fanciulli M., Appella E., Soddu S. Homeodomain-interacting protein kinase-2 phosphorylates p53 at Ser 46 and mediates apoptosis. Nat. Cell Biol. 2002, 4:11-19.
-
(2002)
Nat. Cell Biol.
, vol.4
, pp. 11-19
-
-
D'Orazi, G.1
Cecchinelli, B.2
Bruno, T.3
Manni, I.4
Higashimoto, Y.5
Saito, S.6
Gostissa, M.7
Coen, S.8
Marchetti, A.9
Del Sal, G.10
Piaggio, G.11
Fanciulli, M.12
Appella, E.13
Soddu, S.14
-
13
-
-
0036141392
-
Regulation of p53 activity by its interaction with homeodomain-interacting protein kinase-2
-
Hofmann T.G., Moller A., Sirma H., Zentgraf H., Taya Y., Droge W., Will H., Schmitz M.L. Regulation of p53 activity by its interaction with homeodomain-interacting protein kinase-2. Nat. Cell Biol. 2002, 4:1-10.
-
(2002)
Nat. Cell Biol.
, vol.4
, pp. 1-10
-
-
Hofmann, T.G.1
Moller, A.2
Sirma, H.3
Zentgraf, H.4
Taya, Y.5
Droge, W.6
Will, H.7
Schmitz, M.L.8
-
14
-
-
58149472337
-
The homeodomain-interacting protein kinase 2 regulates insulin promoter factor-1/pancreatic duodenal homeobox-1 transcriptional activity
-
Boucher M.J., Simoneau M., Edlund H. The homeodomain-interacting protein kinase 2 regulates insulin promoter factor-1/pancreatic duodenal homeobox-1 transcriptional activity. Endocrinology 2009, 150:87-97.
-
(2009)
Endocrinology
, vol.150
, pp. 87-97
-
-
Boucher, M.J.1
Simoneau, M.2
Edlund, H.3
-
15
-
-
69949108875
-
Targeting hypoxia in cancer cells by restoring homeodomain interacting protein-kinase 2 and p53 activity and suppressing HIF-1alpha
-
Nardinocchi L., Puca R., Sacchi A., Rechavi G., Givol D., D'Orazi G. Targeting hypoxia in cancer cells by restoring homeodomain interacting protein-kinase 2 and p53 activity and suppressing HIF-1alpha. PLoS ONE 2009, 4:e6819.
-
(2009)
PLoS ONE
, vol.4
-
-
Nardinocchi, L.1
Puca, R.2
Sacchi, A.3
Rechavi, G.4
Givol, D.5
D'Orazi, G.6
-
16
-
-
58149354210
-
An inducible autoregulatory loop between HIPK2 and Siah2 at the apex of the hypoxic response
-
Calzado M.A., de la Vega L., Moller A., Bowtell D.D., Schmitz M.L. An inducible autoregulatory loop between HIPK2 and Siah2 at the apex of the hypoxic response. Nat. Cell Biol. 2009, 11:85-91.
-
(2009)
Nat. Cell Biol.
, vol.11
, pp. 85-91
-
-
Calzado, M.A.1
de la Vega, L.2
Moller, A.3
Bowtell, D.D.4
Schmitz, M.L.5
-
17
-
-
33645238760
-
Overlapping roles for homeodomain-interacting protein kinases hipk1 and hipk2 in the mediation of cell growth in response to morphogenetic and genotoxic signals
-
Isono K., Nemoto K., Li Y., Takada Y., Suzuki R., Katsuki M., Nakagawara A., Koseki H. Overlapping roles for homeodomain-interacting protein kinases hipk1 and hipk2 in the mediation of cell growth in response to morphogenetic and genotoxic signals. Mol. Cell. Biol. 2006, 26:2758-2771.
-
(2006)
Mol. Cell. Biol.
, vol.26
, pp. 2758-2771
-
-
Isono, K.1
Nemoto, K.2
Li, Y.3
Takada, Y.4
Suzuki, R.5
Katsuki, M.6
Nakagawara, A.7
Koseki, H.8
-
18
-
-
34548740091
-
HIPK2 represses beta-catenin-mediated transcription, epidermal stem cell expansion, and skin tumorigenesis
-
Wei G., Ku S., Ma G.K., Saito S., Tang A.A., Zhang J., Mao J.H., Appella E., Balmain A., Huang E.J. HIPK2 represses beta-catenin-mediated transcription, epidermal stem cell expansion, and skin tumorigenesis. Proc. Natl Acad. Sci. USA 2007, 104:13040-13045.
-
(2007)
Proc. Natl Acad. Sci. USA
, vol.104
, pp. 13040-13045
-
-
Wei, G.1
Ku, S.2
Ma, G.K.3
Saito, S.4
Tang, A.A.5
Zhang, J.6
Mao, J.H.7
Appella, E.8
Balmain, A.9
Huang, E.J.10
-
19
-
-
2442678753
-
PML is required for homeodomain-interacting protein kinase 2 (HIPK2)-mediated p53 phosphorylation and cell cycle arrest but is dispensable for the formation of HIPK domains
-
Moller A., Sirma H., Hofmann T.G., Rueffer S., Klimczak E., Droge W., Will H., Schmitz M.L. PML is required for homeodomain-interacting protein kinase 2 (HIPK2)-mediated p53 phosphorylation and cell cycle arrest but is dispensable for the formation of HIPK domains. Cancer Res. 2003, 63:4310-4314.
-
(2003)
Cancer Res.
, vol.63
, pp. 4310-4314
-
-
Moller, A.1
Sirma, H.2
Hofmann, T.G.3
Rueffer, S.4
Klimczak, E.5
Droge, W.6
Will, H.7
Schmitz, M.L.8
-
20
-
-
53249124722
-
HIPKs: Jack of all trades in basic nuclear activities
-
Rinaldo C., Siepi F., Prodosmo A., Soddu S. HIPKs: Jack of all trades in basic nuclear activities. Biochim. Biophys. Acta 2008, 1783:2124-2129.
-
(2008)
Biochim. Biophys. Acta
, vol.1783
, pp. 2124-2129
-
-
Rinaldo, C.1
Siepi, F.2
Prodosmo, A.3
Soddu, S.4
-
21
-
-
33847398755
-
High-mobility group A1 inhibits p53 by cytoplasmic relocalization of its proapoptotic activator HIPK2
-
Pierantoni G.M., Rinaldo C., Mottolese M., Di Benedetto A., Esposito F., Soddu S., Fusco A. High-mobility group A1 inhibits p53 by cytoplasmic relocalization of its proapoptotic activator HIPK2. J. Clin. Invest. 2007, 117:693-702.
-
(2007)
J. Clin. Invest.
, vol.117
, pp. 693-702
-
-
Pierantoni, G.M.1
Rinaldo, C.2
Mottolese, M.3
Di Benedetto, A.4
Esposito, F.5
Soddu, S.6
Fusco, A.7
-
22
-
-
23844433285
-
Regulation of homeodomain-interacting protein kinase 2 (HIPK2) effector function through dynamic small ubiquitin-related modifier-1 (SUMO-1) modification
-
Hofmann T.G., Jaffray E., Stollberg N., Hay R.T., Will H. Regulation of homeodomain-interacting protein kinase 2 (HIPK2) effector function through dynamic small ubiquitin-related modifier-1 (SUMO-1) modification. J. Biol. Chem. 2005, 280:29224-29232.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 29224-29232
-
-
Hofmann, T.G.1
Jaffray, E.2
Stollberg, N.3
Hay, R.T.4
Will, H.5
-
23
-
-
17644377920
-
Covalent modification of human homeodomain interacting protein kinase 2 by SUMO-1 at lysine 25 affects its stability
-
Gresko E., Moller A., Roscic A., Schmitz M.L. Covalent modification of human homeodomain interacting protein kinase 2 by SUMO-1 at lysine 25 affects its stability. Biochem. Biophys. Res. Commun. 2005, 329:1293-1299.
-
(2005)
Biochem. Biophys. Res. Commun.
, vol.329
, pp. 1293-1299
-
-
Gresko, E.1
Moller, A.2
Roscic, A.3
Schmitz, M.L.4
-
24
-
-
33749058094
-
Phosphorylation-dependent control of Pc2 SUMO E3 ligase activity by its substrate protein HIPK2
-
Roscic A., Moller A., Calzado M.A., Renner F., Wimmer V.C., Gresko E., Ludi K.S., Schmitz M.L. Phosphorylation-dependent control of Pc2 SUMO E3 ligase activity by its substrate protein HIPK2. Mol. Cell 2006, 24:77-89.
-
(2006)
Mol. Cell
, vol.24
, pp. 77-89
-
-
Roscic, A.1
Moller, A.2
Calzado, M.A.3
Renner, F.4
Wimmer, V.C.5
Gresko, E.6
Ludi, K.S.7
Schmitz, M.L.8
-
25
-
-
0347790260
-
Covalent modification of the homeodomain-interacting protein kinase 2 (HIPK2) by the ubiquitin-like protein SUMO-1
-
Kim Y.H., Choi C.Y., Kim Y. Covalent modification of the homeodomain-interacting protein kinase 2 (HIPK2) by the ubiquitin-like protein SUMO-1. Proc. Natl Acad. Sci. USA 1999, 96:12350-12355.
-
(1999)
Proc. Natl Acad. Sci. USA
, vol.96
, pp. 12350-12355
-
-
Kim, Y.H.1
Choi, C.Y.2
Kim, Y.3
-
26
-
-
59649100178
-
PML tumor suppressor is regulated by HIPK2-mediated phosphorylation in response to DNA damage
-
Gresko E., Ritterhoff S., Sevilla-Perez J., Roscic A., Frobius K., Kotevic I., Vichalkovski A., Hess D., Hemmings B.A., Schmitz M.L. PML tumor suppressor is regulated by HIPK2-mediated phosphorylation in response to DNA damage. Oncogene 2009, 28:698-708.
-
(2009)
Oncogene
, vol.28
, pp. 698-708
-
-
Gresko, E.1
Ritterhoff, S.2
Sevilla-Perez, J.3
Roscic, A.4
Frobius, K.5
Kotevic, I.6
Vichalkovski, A.7
Hess, D.8
Hemmings, B.A.9
Schmitz, M.L.10
-
27
-
-
13244271351
-
Multiple activities contribute to Pc2 E3 function
-
Kagey M.H., Melhuish T.A., Powers S.E., Wotton D. Multiple activities contribute to Pc2 E3 function. EMBO J. 2005, 24:108-119.
-
(2005)
EMBO J.
, vol.24
, pp. 108-119
-
-
Kagey, M.H.1
Melhuish, T.A.2
Powers, S.E.3
Wotton, D.4
-
28
-
-
0037174882
-
Two highly related p66 proteins comprise a new family of potent transcriptional repressors interacting with MBD2 and MBD3
-
Brackertz M., Boeke J., Zhang R., Renkawitz R. Two highly related p66 proteins comprise a new family of potent transcriptional repressors interacting with MBD2 and MBD3. J. Biol. Chem. 2002, 277:40958-40966.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 40958-40966
-
-
Brackertz, M.1
Boeke, J.2
Zhang, R.3
Renkawitz, R.4
-
29
-
-
0021716406
-
A short amino acid sequence able to specify nuclear location
-
Kalderon D., Roberts B.L., Richardson W.D., Smith A.E. A short amino acid sequence able to specify nuclear location. Cell 1984, 39:499-509.
-
(1984)
Cell
, vol.39
, pp. 499-509
-
-
Kalderon, D.1
Roberts, B.L.2
Richardson, W.D.3
Smith, A.E.4
-
30
-
-
0036646102
-
Deconstructing PML-induced premature senescence
-
Bischof O., Kirsh O., Pearson M., Itahana K., Pelicci P.G., Dejean A. Deconstructing PML-induced premature senescence. EMBO J. 2002, 21:3358-3369.
-
(2002)
EMBO J.
, vol.21
, pp. 3358-3369
-
-
Bischof, O.1
Kirsh, O.2
Pearson, M.3
Itahana, K.4
Pelicci, P.G.5
Dejean, A.6
-
31
-
-
33745813187
-
Reading protein modifications with interaction domains
-
Seet B.T., Dikic I., Zhou M.M., Pawson T. Reading protein modifications with interaction domains. Nat. Rev. Mol. Cell Biol. 2006, 7:473-483.
-
(2006)
Nat. Rev. Mol. Cell Biol.
, vol.7
, pp. 473-483
-
-
Seet, B.T.1
Dikic, I.2
Zhou, M.M.3
Pawson, T.4
-
32
-
-
77950643586
-
The SUMO E3 ligase activity of Pc2 is coordinated through a SUMO interaction motif
-
Yang S.H., Sharrocks A.D. The SUMO E3 ligase activity of Pc2 is coordinated through a SUMO interaction motif. Mol. Cell. Biol. 2010, 30:2193-2205.
-
(2010)
Mol. Cell. Biol.
, vol.30
, pp. 2193-2205
-
-
Yang, S.H.1
Sharrocks, A.D.2
-
33
-
-
77649328923
-
A role for non-covalent SUMO interaction motifs in Pc2/CBX4 E3 activity
-
Merrill J.C., Melhuish T.A., Kagey M.H., Yang S.H., Sharrocks A.D., Wotton D. A role for non-covalent SUMO interaction motifs in Pc2/CBX4 E3 activity. PLoS ONE 2010, 5:e8794.
-
(2010)
PLoS ONE
, vol.5
-
-
Merrill, J.C.1
Melhuish, T.A.2
Kagey, M.H.3
Yang, S.H.4
Sharrocks, A.D.5
Wotton, D.6
-
34
-
-
57649198342
-
Small ubiquitin-related modifier (SUMO) binding determines substrate recognition and paralog-selective SUMO modification
-
Zhu J., Zhu S., Guzzo C.M., Ellis N.A., Sung K.S., Choi C.Y., Matunis M.J. Small ubiquitin-related modifier (SUMO) binding determines substrate recognition and paralog-selective SUMO modification. J. Biol. Chem. 2008, 283:29405-29415.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 29405-29415
-
-
Zhu, J.1
Zhu, S.2
Guzzo, C.M.3
Ellis, N.A.4
Sung, K.S.5
Choi, C.Y.6
Matunis, M.J.7
-
35
-
-
1542285164
-
SUMO promotes HDAC-mediated transcriptional repression
-
Yang S.H., Sharrocks A.D. SUMO promotes HDAC-mediated transcriptional repression. Mol. Cell 2004, 13:611-617.
-
(2004)
Mol. Cell
, vol.13
, pp. 611-617
-
-
Yang, S.H.1
Sharrocks, A.D.2
-
36
-
-
33750447586
-
The mechanisms of PML-nuclear body formation
-
Shen T.H., Lin H.K., Scaglioni P.P., Yung T.M., Pandolfi P.P. The mechanisms of PML-nuclear body formation. Mol. Cell 2006, 24:331-339.
-
(2006)
Mol. Cell
, vol.24
, pp. 331-339
-
-
Shen, T.H.1
Lin, H.K.2
Scaglioni, P.P.3
Yung, T.M.4
Pandolfi, P.P.5
-
37
-
-
27544498904
-
Desumoylation of homeodomain-interacting protein kinase 2 (HIPK2) through the cytoplasmic-nuclear shuttling of the SUMO-specific protease SENP1
-
Kim Y.H., Sung K.S., Lee S.J., Kim Y.O., Choi C.Y., Kim Y. Desumoylation of homeodomain-interacting protein kinase 2 (HIPK2) through the cytoplasmic-nuclear shuttling of the SUMO-specific protease SENP1. FEBS Lett. 2005, 579:6272-6278.
-
(2005)
FEBS Lett.
, vol.579
, pp. 6272-6278
-
-
Kim, Y.H.1
Sung, K.S.2
Lee, S.J.3
Kim, Y.O.4
Choi, C.Y.5
Kim, Y.6
|