-
1
-
-
53249124722
-
HIPKs: Jack of all trades in basic nuclear activities
-
Rinaldo C, Siepi F, Prodosmo A, Soddu S, (2008) HIPKs: Jack of all trades in basic nuclear activities. Biochimica et Biophysica Acta 1783: 2124-2129.
-
(2008)
Biochimica Et Biophysica Acta
, vol.1783
, pp. 2124-2129
-
-
Rinaldo, C.1
Siepi, F.2
Prodosmo, A.3
Soddu, S.4
-
2
-
-
18244379872
-
Homeodomain-interacting protein kinase-2 phosphorylates p53 at Ser 46 and mediates apoptosis
-
D'Orazi G, Cecchinelli B, Bruno T, Manni I, Higashimoto Y, et al. (2002) Homeodomain-interacting protein kinase-2 phosphorylates p53 at Ser 46 and mediates apoptosis. Nat Cell Biol 4 (1): 11-19.
-
(2002)
Nat Cell Biol
, vol.4
, Issue.1
, pp. 11-19
-
-
D'Orazi, G.1
Cecchinelli, B.2
Bruno, T.3
Manni, I.4
Higashimoto, Y.5
-
3
-
-
0036141392
-
Regulation of p53 activity by its interaction with homeodomain-interacting protein kinase-2
-
Hofmann TG, Möller A, Sirma H, Zentgraf H, Taya Y, et al. (2002) Regulation of p53 activity by its interaction with homeodomain-interacting protein kinase-2. Nat Cell Biol 4 (1): 1-10.
-
(2002)
Nat Cell Biol
, vol.4
, Issue.1
, pp. 1-10
-
-
Hofmann, T.G.1
Möller, A.2
Sirma, H.3
Zentgraf, H.4
Taya, Y.5
-
4
-
-
33846913249
-
HIPK2: a versatile switchboard regulating the transcription machinery and cell death
-
Calzado MA, Renner F, Roscic A, Schmitz ML, (2007) HIPK2: a versatile switchboard regulating the transcription machinery and cell death. Cell Cycle 6: 139-143.
-
(2007)
Cell Cycle
, vol.6
, pp. 139-143
-
-
Calzado, M.A.1
Renner, F.2
Roscic, A.3
Schmitz, M.L.4
-
5
-
-
34948910811
-
HIPK2: a multitalented partner for transcription factors in DNA damage response and development
-
Rinaldo C, Prodosmo A, Siepi F, Soddu S, (2007) HIPK2: a multitalented partner for transcription factors in DNA damage response and development. Biochem Cell Biol 85 (4): 411-418.
-
(2007)
Biochem Cell Biol
, vol.85
, Issue.4
, pp. 411-418
-
-
Rinaldo, C.1
Prodosmo, A.2
Siepi, F.3
Soddu, S.4
-
6
-
-
36048957154
-
Mutations of the HIPK2 gene in acute myeloid leukemia and myelodysplastic syndrome impair AML1- and p53-mediated transcription
-
Li XL, Arai Y, Harada H, Shima Y, Yoshida H, et al. (2007) Mutations of the HIPK2 gene in acute myeloid leukemia and myelodysplastic syndrome impair AML1- and p53-mediated transcription. Oncogene 26: 7231-7239.
-
(2007)
Oncogene
, vol.26
, pp. 7231-7239
-
-
Li, X.L.1
Arai, Y.2
Harada, H.3
Shima, Y.4
Yoshida, H.5
-
7
-
-
33847398755
-
High-mobility group A1 inhibits p53 by cytoplasmic relocalization of its proapoptotic activator HIPK2
-
Pierantoni GM, Rinaldo C, Mottolese M, Di Benedetto A, Esposito F, et al. (2007) High-mobility group A1 inhibits p53 by cytoplasmic relocalization of its proapoptotic activator HIPK2. J Clin Invest 117: 693-702.
-
(2007)
J Clin Invest
, vol.117
, pp. 693-702
-
-
Pierantoni, G.M.1
Rinaldo, C.2
Mottolese, M.3
Di Benedetto, A.4
Esposito, F.5
-
8
-
-
0035959740
-
High mobility group I (Y) proteins bind HIPK2, a serine-threonine kinase protein which inhibits cell growth
-
Pierantoni GM, Fedele M, Pentimalli F, Benvenuto G, Pero R, et al. (2001) High mobility group I (Y) proteins bind HIPK2, a serine-threonine kinase protein which inhibits cell growth. Oncogene 20: 6132-6141.
-
(2001)
Oncogene
, vol.20
, pp. 6132-6141
-
-
Pierantoni, G.M.1
Fedele, M.2
Pentimalli, F.3
Benvenuto, G.4
Pero, R.5
-
9
-
-
0036297331
-
The homeodomain-interacting protein kinase 2 gene is expressed late in embryogenesis and preferentially in retina, muscle, and neural tissues
-
Pierantoni GM, Bulfone A, Pentimalli F, Fedele M, Iuliano R, et al. (2002) The homeodomain-interacting protein kinase 2 gene is expressed late in embryogenesis and preferentially in retina, muscle, and neural tissues. Biochem Biophys Res Commun 290: 942-947.
-
(2002)
Biochem Biophys Res Commun
, vol.290
, pp. 942-947
-
-
Pierantoni, G.M.1
Bulfone, A.2
Pentimalli, F.3
Fedele, M.4
Iuliano, R.5
-
10
-
-
33745020886
-
Repression of the antiapoptotic molecule galectin-3 by homeodomain-interacting protein kinase 2-activated p53 is required for p53-induced apoptosis
-
Cecchinelli B, Lavra L, Rinaldo C, Iacovelli S, Gurtner A, et al. (2006) Repression of the antiapoptotic molecule galectin-3 by homeodomain-interacting protein kinase 2-activated p53 is required for p53-induced apoptosis. Mol Cell Biol 26: 4746-4757.
-
(2006)
Mol Cell Biol
, vol.26
, pp. 4746-4757
-
-
Cecchinelli, B.1
Lavra, L.2
Rinaldo, C.3
Iacovelli, S.4
Gurtner, A.5
-
11
-
-
34447106403
-
The role of galectin-3 in cancer drug resistance
-
Fukumori T, Kanayama HO, Raz A, (2007) The role of galectin-3 in cancer drug resistance. Drug Resist Updat 10: 101-108.
-
(2007)
Drug Resist Updat
, vol.10
, pp. 101-108
-
-
Fukumori, T.1
Kanayama, H.O.2
Raz, A.3
-
12
-
-
18044396712
-
On the role of galectin-3 in cancer apoptosis
-
Nakahara S, Oka N, Raz A, (2005) On the role of galectin-3 in cancer apoptosis. Apoptosis 10: 267-275.
-
(2005)
Apoptosis
, vol.10
, pp. 267-275
-
-
Nakahara, S.1
Oka, N.2
Raz, A.3
-
13
-
-
0030707480
-
Galectin-3: a novel antiapoptotic molecule with a functional BH1 (NWGR) domain of Bcl-2 family
-
Akahani S, Nangia-Makker P, Inohara H, Kim HR, Raz A, (1997) Galectin-3: a novel antiapoptotic molecule with a functional BH1 (NWGR) domain of Bcl-2 family. Cancer Res 57: 5272-5276.
-
(1997)
Cancer Res
, vol.57
, pp. 5272-5276
-
-
Akahani, S.1
Nangia-Makker, P.2
Inohara, H.3
Kim, H.R.4
Raz, A.5
-
14
-
-
0037013214
-
Galectin-3 translocates to the perinuclear membranes and inhibits cytochrome c release from the mitochondria. A role for synexin in galectin-3 translocation
-
Yu F, Finley RL Jr, Raz A, Kim HR, (2002) Galectin-3 translocates to the perinuclear membranes and inhibits cytochrome c release from the mitochondria. A role for synexin in galectin-3 translocation. J Biol Chem 277: 15819-15827.
-
(2002)
J Biol Chem
, vol.277
, pp. 15819-15827
-
-
Yu, F.1
Finley Jr., R.L.2
Raz, A.3
Kim, H.R.4
-
16
-
-
0035319230
-
Galectin-3 maintains the transformed phenotype of thyroid papillary carcinoma cells
-
Yoshii T, Inohara H, Takenaka Y, Honjo Y, Akahani S, et al. (2001) Galectin-3 maintains the transformed phenotype of thyroid papillary carcinoma cells. Int J Oncol 18: 787-792.
-
(2001)
Int J Oncol
, vol.18
, pp. 787-792
-
-
Yoshii, T.1
Inohara, H.2
Takenaka, Y.3
Honjo, Y.4
Akahani, S.5
-
17
-
-
72449155680
-
Galectin-3 targeted therapy with a small molecule inhibitor activates apoptosis and enhances both chemosensitivity and radiosensitivity in papillary thyroid cancer
-
Lin CI, Whang EE, Donner DB, Jiang X, Price BD, et al. (2009) Galectin-3 targeted therapy with a small molecule inhibitor activates apoptosis and enhances both chemosensitivity and radiosensitivity in papillary thyroid cancer. Mol Cancer Res 7: 1655-1662.
-
(2009)
Mol Cancer Res
, vol.7
, pp. 1655-1662
-
-
Lin, C.I.1
Whang, E.E.2
Donner, D.B.3
Jiang, X.4
Price, B.D.5
-
18
-
-
0035954068
-
Application of an immunodiagnostic method for improving preoperative diagnosis of nodular thyroid lesions
-
Bartolazzi A, Gasbarri A, Papotti M, Bussolati G, Lucante T, et al. (2001) Application of an immunodiagnostic method for improving preoperative diagnosis of nodular thyroid lesions. Lancet 357: 1644-1650.
-
(2001)
Lancet
, vol.357
, pp. 1644-1650
-
-
Bartolazzi, A.1
Gasbarri, A.2
Papotti, M.3
Bussolati, G.4
Lucante, T.5
-
19
-
-
66749085092
-
Gal-3 is stimulated by gain-of-function p53 mutations and modulates chemoresistance in anaplastic thyroid carcinomas
-
Lavra L, Ulivieri A, Rinaldo C, Dominici R, Volante M, et al. (2009) Gal-3 is stimulated by gain-of-function p53 mutations and modulates chemoresistance in anaplastic thyroid carcinomas. J Pathol 218: 66-75.
-
(2009)
J Pathol
, vol.218
, pp. 66-75
-
-
Lavra, L.1
Ulivieri, A.2
Rinaldo, C.3
Dominici, R.4
Volante, M.5
-
20
-
-
44249090141
-
Galectin-3-expression analysis in the surgical selection of follicular thyroid nodules with indeterminate fine-needle aspiration cytology: a prospective multicentre study
-
Bartolazzi A, Orlandi F, Saggiorato E, Volante M, Arecco F, et al. (2008) Galectin-3-expression analysis in the surgical selection of follicular thyroid nodules with indeterminate fine-needle aspiration cytology: a prospective multicentre study. Lancet Oncol 9: 543-549.
-
(2008)
Lancet Oncol
, vol.9
, pp. 543-549
-
-
Bartolazzi, A.1
Orlandi, F.2
Saggiorato, E.3
Volante, M.4
Arecco, F.5
-
21
-
-
0027455042
-
High prevalence of mutations of the p53 gene in poorly differentiated human thyroid carcinomas
-
Fagin JA, Matsuo K, Karmakar A, Chen DL, Tang SH, et al. (1993) High prevalence of mutations of the p53 gene in poorly differentiated human thyroid carcinomas. J Clin Invest 91: 179-184.
-
(1993)
J Clin Invest
, vol.91
, pp. 179-184
-
-
Fagin, J.A.1
Matsuo, K.2
Karmakar, A.3
Chen, D.L.4
Tang, S.H.5
-
22
-
-
0027215123
-
Gene p53 mutations are restricted to poorly differentiated and undifferentiated carcinomas of the thyroid gland
-
Donghi R, Longoni A, Pilotti S, Michieli P, Della Porta G, et al. (1993) Gene p53 mutations are restricted to poorly differentiated and undifferentiated carcinomas of the thyroid gland. J Clin Invest 91: 1753-1760.
-
(1993)
J Clin Invest
, vol.91
, pp. 1753-1760
-
-
Donghi, R.1
Longoni, A.2
Pilotti, S.3
Michieli, P.4
Della Porta, G.5
-
23
-
-
0032503506
-
Cyclin D1 and Cyclin E expression in malignant thyroid cells and in human thyroid carcinomas
-
Lazzereschi D, Sambuco L, Carnovale Scalzo C, Ranieri A, Mincione G, et al. (1998) Cyclin D1 and Cyclin E expression in malignant thyroid cells and in human thyroid carcinomas. Int J Cancer 76: 806-811.
-
(1998)
Int J Cancer
, vol.76
, pp. 806-811
-
-
Lazzereschi, D.1
Sambuco, L.2
Carnovale Scalzo, C.3
Ranieri, A.4
Mincione, G.5
-
24
-
-
0027434353
-
Immunohistochemical analysis of the p53 oncoprotein on paraffin sections using a series of novel monoclonal antibodies
-
Bártek J, Bártková J, Lukás J, Stasková Z, Vojtsek B, et al. (1993) Immunohistochemical analysis of the p53 oncoprotein on paraffin sections using a series of novel monoclonal antibodies. J Pathol 169: 27-34.
-
(1993)
J Pathol
, vol.169
, pp. 27-34
-
-
Bártek, J.1
Bártková, J.2
Lukás, J.3
Stasková, Z.4
Vojtsek, B.5
-
25
-
-
3042547289
-
Clinico-pathological significance of cell-type-specific loss of heterozygosity on chromosome 7q21: analysis of 318 microdissected thyroid lesions
-
Trovato M, Ulivieri A, Dominici R, Ruggeri RM, Vitarelli E, et al. (2004) Clinico-pathological significance of cell-type-specific loss of heterozygosity on chromosome 7q21: analysis of 318 microdissected thyroid lesions. Endocr Relat Cancer 11: 365-376.
-
(2004)
Endocr Relat Cancer
, vol.11
, pp. 365-376
-
-
Trovato, M.1
Ulivieri, A.2
Dominici, R.3
Ruggeri, R.M.4
Vitarelli, E.5
-
26
-
-
0034853599
-
Allelotyping of follicular thyroid carcinoma: frequent allelic losses in chromosome arms 7q, 11p, and 22q
-
Kitamura Y, Shimizu K, Ito K, Tanaka S, Emi M, (2001) Allelotyping of follicular thyroid carcinoma: frequent allelic losses in chromosome arms 7q, 11p, and 22q. J Clin Endocrinol Metab 86: 4268-4272.
-
(2001)
J Clin Endocrinol Metab
, vol.86
, pp. 4268-4272
-
-
Kitamura, Y.1
Shimizu, K.2
Ito, K.3
Tanaka, S.4
Emi, M.5
-
27
-
-
0032514375
-
Differential loss of heterozygosity at 7q31.2 in follicular and papillary thyroid tumors
-
Zhang JS, Nelson M, McIver B, Hay ID, Goellner JR, et al. (1998) Differential loss of heterozygosity at 7q31.2 in follicular and papillary thyroid tumors. Oncogene 17: 789-793.
-
(1998)
Oncogene
, vol.17
, pp. 789-793
-
-
Zhang, J.S.1
Nelson, M.2
McIver, B.3
Hay, I.D.4
Goellner, J.R.5
-
28
-
-
0034173026
-
Thyroid cancer following exposure to radioactive iodine
-
Robbins J, Schneider AB, (2000) Thyroid cancer following exposure to radioactive iodine. Rev Endocr Metab Disord 1: 197-203.
-
(2000)
Rev Endocr Metab Disord
, vol.1
, pp. 197-203
-
-
Robbins, J.1
Schneider, A.B.2
-
29
-
-
33750603975
-
Long-term risks for thyroid cancer and other neoplasms after exposure to radiation
-
Schneider AB, Sarne DH, (2005) Long-term risks for thyroid cancer and other neoplasms after exposure to radiation. Nat Clin Pract Endocrinol Metab 1: 82-91.
-
(2005)
Nat Clin Pract Endocrinol Metab
, vol.1
, pp. 82-91
-
-
Schneider, A.B.1
Sarne, D.H.2
-
30
-
-
77950232947
-
Is ionizing radiation responsible for the increasing incidence of thyroid cancer?
-
Nikiforov YE, (2010) Is ionizing radiation responsible for the increasing incidence of thyroid cancer? Cancer 116: 1626-1628.
-
(2010)
Cancer
, vol.116
, pp. 1626-1628
-
-
Nikiforov, Y.E.1
-
31
-
-
65349105355
-
HIPK2 is involved in cell proliferation and its suppression promotes growth arrest independently of DNA damage
-
Iacovelli S, Ciuffini L, Lazzari C, Bracaglia G, Rinaldo C, et al. (2009) HIPK2 is involved in cell proliferation and its suppression promotes growth arrest independently of DNA damage. Cell Prolif 42: 373-384.
-
(2009)
Cell Prolif
, vol.42
, pp. 373-384
-
-
Iacovelli, S.1
Ciuffini, L.2
Lazzari, C.3
Bracaglia, G.4
Rinaldo, C.5
-
32
-
-
0036023418
-
Clinicopathological significance of galectin-3 expression in ductal adenocarcinoma of the pancreas
-
Shimamura T, Sakamoto M, Ino Y, Shimada K, Kosuge T, (2002) Clinicopathological significance of galectin-3 expression in ductal adenocarcinoma of the pancreas. Clin Cancer Res 8: 2570-2575.
-
(2002)
Clin Cancer Res
, vol.8
, pp. 2570-2575
-
-
Shimamura, T.1
Sakamoto, M.2
Ino, Y.3
Shimada, K.4
Kosuge, T.5
-
33
-
-
0037106507
-
Lack of expression of galectin-3 is associated with a poor outcome in node-negative patients with laryngeal squamous-cell carcinoma
-
Piantelli M, Iacobelli S, Almadori G, Iezzi M, Tinari N, et al. (2002) Lack of expression of galectin-3 is associated with a poor outcome in node-negative patients with laryngeal squamous-cell carcinoma. J Clin Oncol 20: 3850-3856.
-
(2002)
J Clin Oncol
, vol.20
, pp. 3850-3856
-
-
Piantelli, M.1
Iacobelli, S.2
Almadori, G.3
Iezzi, M.4
Tinari, N.5
-
34
-
-
33645811957
-
Reduced galectin-3 expression is an indicator of unfavorable prognosis in gastric cancer
-
Okada K, Shimura T, Suehiro T, Mochiki E, Kuwano H, (2006) Reduced galectin-3 expression is an indicator of unfavorable prognosis in gastric cancer. Anticancer Res 26: 1369-1376.
-
(2006)
Anticancer Res
, vol.26
, pp. 1369-1376
-
-
Okada, K.1
Shimura, T.2
Suehiro, T.3
Mochiki, E.4
Kuwano, H.5
-
35
-
-
0034065728
-
Galectin-3 expression in various thyroid neoplasms and its possible role in metastasis formation
-
Kawachi K, Matsushita Y, Yonezawa S, Nakano S, Shirao K, et al. (2000) Galectin-3 expression in various thyroid neoplasms and its possible role in metastasis formation. Hum Pathol 31: 428-433.
-
(2000)
Hum Pathol
, vol.31
, pp. 428-433
-
-
Kawachi, K.1
Matsushita, Y.2
Yonezawa, S.3
Nakano, S.4
Shirao, K.5
-
36
-
-
0032889647
-
Frequent deletions within FRA7G at 7q312 in invasive epithelial ovarian cancer
-
Huang H, Reed CP, Mordi A, Lomberk G, Wang L, et al. (1999) Frequent deletions within FRA7G at 7q312 in invasive epithelial ovarian cancer. Genes Chromosomes Cancer 24: 48-55.
-
(1999)
Genes Chromosomes Cancer
, vol.24
, pp. 48-55
-
-
Huang, H.1
Reed, C.P.2
Mordi, A.3
Lomberk, G.4
Wang, L.5
-
37
-
-
0034704856
-
Definitive functional evidence for a tumor suppressor gene on human chromosome 7q31.1 neighboring the Fra7G site
-
Zenklusen JC, Hodges LC, LaCava M, Green ED, Conti CJ, (2000) Definitive functional evidence for a tumor suppressor gene on human chromosome 7q31.1 neighboring the Fra7G site. Oncogene 19: 1729-1733.
-
(2000)
Oncogene
, vol.19
, pp. 1729-1733
-
-
Zenklusen, J.C.1
Hodges, L.C.2
LaCava, M.3
Green, E.D.4
Conti, C.J.5
-
38
-
-
0037293054
-
Candidate tumor suppressor genes at FRA7G are coamplified with MET and do not suppress malignancy in a gastric cancer
-
Han SY, Druck T, Huebner K, (2003) Candidate tumor suppressor genes at FRA7G are coamplified with MET and do not suppress malignancy in a gastric cancer. Genomics 81: 105-107.
-
(2003)
Genomics
, vol.81
, pp. 105-107
-
-
Han, S.Y.1
Druck, T.2
Huebner, K.3
-
39
-
-
34247189647
-
Tumours of thyroid and parathyroid. In WHO Classification of Tumours: Pathology and Genetics of Tumours of Endocrine Organs
-
In: DeLellis RA, Lloyd RV, Heitz PU, Eng C, editors, Geneva/IARC, Lyon, World Health Organization
-
Li Volsi VA, Albores-SaAvedra J, Asa SL, Baloch ZW, Sobrinho-Simoes M, et al. (2004) Tumours of thyroid and parathyroid. In WHO Classification of Tumours: Pathology and Genetics of Tumours of Endocrine Organs. In: DeLellis RA, Lloyd RV, Heitz PU, Eng C, editors. Geneva/IARC, Lyon World Health Organization pp. 49-100.
-
(2004)
, pp. 49-100
-
-
Li Volsi, V.A.1
Albores-SaAvedra, J.2
Asa, S.L.3
Baloch, Z.W.4
Sobrinho-Simoes, M.5
-
40
-
-
34248177447
-
Poorly differentiated thyroid carcinoma: the Turin proposal for the use of uniform diagnostic criteria and an algorithmic diagnostic approach
-
Volante M, Collini P, Nikiforov YE, Sakamoto A, Kakudo K, et al. (2007) Poorly differentiated thyroid carcinoma: the Turin proposal for the use of uniform diagnostic criteria and an algorithmic diagnostic approach. Am J Surg Pathol 31: 1256-1264.
-
(2007)
Am J Surg Pathol
, vol.31
, pp. 1256-1264
-
-
Volante, M.1
Collini, P.2
Nikiforov, Y.E.3
Sakamoto, A.4
Kakudo, K.5
-
41
-
-
42949110059
-
Frizzled-1 is down-regulated in follicular thyroid tumours and modulates growth and invasiveness
-
Ulivieri A, Lavra L, Dominici R, Giacomelli L, Brunetti E, et al. (2008) Frizzled-1 is down-regulated in follicular thyroid tumours and modulates growth and invasiveness. J Pathol 215: 87-96.
-
(2008)
J Pathol
, vol.215
, pp. 87-96
-
-
Ulivieri, A.1
Lavra, L.2
Dominici, R.3
Giacomelli, L.4
Brunetti, E.5
-
42
-
-
0035710746
-
Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method
-
Livak KJ, Schmittgen TD, (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 25: 402-408.
-
(2001)
Methods
, vol.25
, pp. 402-408
-
-
Livak, K.J.1
Schmittgen, T.D.2
-
43
-
-
18544381909
-
A high-resolution recombination map of the human genome
-
Kong A, Gudbjartsson DF, Sainz J, Jonsdottir GM, Gudjonsson SA, et al. (2002) A high-resolution recombination map of the human genome. Nat Genet 31: 241-247.
-
(2002)
Nat Genet
, vol.31
, pp. 241-247
-
-
Kong, A.1
Gudbjartsson, D.F.2
Sainz, J.3
Jonsdottir, G.M.4
Gudjonsson, S.A.5
|