Mutual regulation between SIAH2 and DYRK2 controls hypoxic and genotoxic signaling pathways

Journal of Molecular Cell Biology

Volumn 4, Issue 5, 2012, Pages 316-330

  Pérez, Moisés ^a   García Limones, Carmen ^a   Zapico, Inés ^b   Marina, Anabel ^b   Schmitz, M Lienhard ^c,d   Muñoz, Eduardo ^a   Calzado, Marco A ^a  

^a UNIVERSITY OF CÓRDOBA   (Spain)

^b UNIVERSIDAD AUTÓNOMA DE MADRID   (Spain)

^c Institute of Biochemistry   (Germany)

^d German Center for Lung Research   (Germany)

Author keywords

DYRK2; hypoxia; phosphorylation; SIAH2; ubiquitination

Indexed keywords

HYPOXIA INDUCIBLE FACTOR 1ALPHA; PROCOLLAGEN PROLINE 2 OXOGLUTARATE 4 DIOXYGENASE; PROTEIN P53; PROTEIN SERINE THREONINE KINASE; PROTEIN SERINE THREONINE KINASE DYRK2; REGULATOR PROTEIN; UBIQUITIN; UBIQUITIN PROTEIN LIGASE E3; UBIQUITIN PROTEIN LIGASE SIAH2; UNCLASSIFIED DRUG;

ANGIOGENESIS; ARTICLE; CONTROLLED STUDY; GENE CONTROL; GENOTOXICITY; HUMAN; HUMAN TISSUE; HYPOXIA; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; UBIQUITINATION;

ANIMALS; BINDING SITES; CELL HYPOXIA; CELL LINE; DNA DAMAGE; HELA CELLS; HUMANS; MICE; NUCLEAR PROTEINS; PROTEIN-SERINE-THREONINE KINASES; PROTEIN-TYROSINE KINASES; SIGNAL TRANSDUCTION; TRANSFECTION; UBIQUITIN; UBIQUITIN-PROTEIN LIGASES; UBIQUITINATION;

EID: 84867410202     PISSN: 16742788     EISSN: 17594685     Source Type: Journal    
DOI: 10.1093/jmcb/mjs047     Document Type: Article

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