-
1
-
-
0022536710
-
Isolation and characterization of a new cellular oncogene encoding a protein with multiple potential transmembrane domains
-
D. Young, G. Waitches, C. Birchmeier, O. Fasano, and M. Wigler Isolation and characterization of a new cellular oncogene encoding a protein with multiple potential transmembrane domains Cell 45 1986 711 719
-
(1986)
Cell
, vol.45
, pp. 711-719
-
-
Young, D.1
Waitches, G.2
Birchmeier, C.3
Fasano, O.4
Wigler, M.5
-
2
-
-
0024385411
-
Ectopic expression of the serotonin 1c receptor and the triggering of malignant transformation
-
D. Julius, T.J. Livelli, T.M. Jessell, and R. Axel Ectopic expression of the serotonin 1c receptor and the triggering of malignant transformation Science 244 1989 1057 1062
-
(1989)
Science
, vol.244
, pp. 1057-1062
-
-
Julius, D.1
Livelli, T.J.2
Jessell, T.M.3
Axel, R.4
-
4
-
-
33644662506
-
Overexpression of G protein-coupled receptors in cancer cells: Involvement in tumor progression
-
S. Li, S. Huang, and S.B. Peng Overexpression of G protein-coupled receptors in cancer cells: involvement in tumor progression Int J Oncol 27 2005 1329 1339
-
(2005)
Int J Oncol
, vol.27
, pp. 1329-1339
-
-
Li, S.1
Huang, S.2
Peng, S.B.3
-
5
-
-
0035398487
-
G-protein-coupled receptors and signaling networks: Emerging paradigms
-
M.J. Marinissen, and J.S. Gutkind G-protein-coupled receptors and signaling networks: emerging paradigms Trends Pharmacol Sci 22 2001 368 376
-
(2001)
Trends Pharmacol Sci
, vol.22
, pp. 368-376
-
-
Marinissen, M.J.1
Gutkind, J.S.2
-
6
-
-
0025212680
-
Regions of the alpha 1-Adrenergic receptor involved in coupling to phosphatidylinositol hydrolysis and enhanced sensitivity of biological function
-
S. Cotecchia, S. Exum, M.G. Caron, and R.J. Lefkowitz Regions of the alpha 1-Adrenergic receptor involved in coupling to phosphatidylinositol hydrolysis and enhanced sensitivity of biological function Proc Natl Acad Sci USA 87 1990 2896 2900
-
(1990)
Proc Natl Acad Sci USA
, vol.87
, pp. 2896-2900
-
-
Cotecchia, S.1
Exum, S.2
Caron, M.G.3
Lefkowitz, R.J.4
-
7
-
-
0026318020
-
G-protein-coupled receptor genes as protooncogenes: Constitutively activating mutation of the alpha 1B-Adrenergic receptor enhances mitogenesis and tumorigenicity
-
L.F. Allen, R.J. Lefkowitz, M.G. Caron, and S. Cotecchia G-protein-coupled receptor genes as protooncogenes: constitutively activating mutation of the alpha 1B-Adrenergic receptor enhances mitogenesis and tumorigenicity Proc Natl Acad Sci USA 88 1991 11354 11358
-
(1991)
Proc Natl Acad Sci USA
, vol.88
, pp. 11354-11358
-
-
Allen, L.F.1
Lefkowitz, R.J.2
Caron, M.G.3
Cotecchia, S.4
-
8
-
-
0029913238
-
An activating mutation of the follicle-stimulating hormone receptor autonomously sustains spermatogenesis in a hypophysectomized man
-
J. Gromoll, M. Simoni, and E. Nieschlag An activating mutation of the follicle-stimulating hormone receptor autonomously sustains spermatogenesis in a hypophysectomized man J Clin Endocrinol Metab 81 1996 1367 1370
-
(1996)
J Clin Endocrinol Metab
, vol.81
, pp. 1367-1370
-
-
Gromoll, J.1
Simoni, M.2
Nieschlag, E.3
-
9
-
-
0028125886
-
Rhodopsin mutation G90D and a molecular mechanism for congenital night blindness
-
V.R. Rao, G.B. Cohen, and D.D. Oprian Rhodopsin mutation G90D and a molecular mechanism for congenital night blindness Nature 367 1994 639 642
-
(1994)
Nature
, vol.367
, pp. 639-642
-
-
Rao, V.R.1
Cohen, G.B.2
Oprian, D.D.3
-
10
-
-
0028943780
-
A constitutively active mutant PTH-PTHrP receptor in Jansen-type metaphyseal chondrodysplasia
-
E. Schipani, K. Kruse, and H. Juppner A constitutively active mutant PTH-PTHrP receptor in Jansen-type metaphyseal chondrodysplasia Science 268 1995 98 100
-
(1995)
Science
, vol.268
, pp. 98-100
-
-
Schipani, E.1
Kruse, K.2
Juppner, H.3
-
11
-
-
0027372340
-
A constitutively activating mutation of the luteinizing hormone receptor in familial male precocious puberty
-
A. Shenker, L. Laue, S. Kosugi, J.J. Merendino Jr., T. Minegishi, and G.B. Cutler Jr. A constitutively activating mutation of the luteinizing hormone receptor in familial male precocious puberty Nature 365 1993 652 654
-
(1993)
Nature
, vol.365
, pp. 652-654
-
-
Shenker, A.1
Laue, L.2
Kosugi, S.3
Merendino, Jr.J.J.4
Minegishi, T.5
Cutler, Jr.G.B.6
-
12
-
-
0027369421
-
Somatic mutations in the thyrotropin receptor gene cause hyperfunctioning thyroid adenomas
-
J. Parma, L. Duprez, J. Van Sande, P. Cochaux, C. Gervy, and J. Mockel Somatic mutations in the thyrotropin receptor gene cause hyperfunctioning thyroid adenomas Nature 365 1993 649 651
-
(1993)
Nature
, vol.365
, pp. 649-651
-
-
Parma, J.1
Duprez, L.2
Van Sande, J.3
Cochaux, P.4
Gervy, C.5
Mockel, J.6
-
13
-
-
10044254636
-
Viral hijacking of G-protein-coupled-receptor signalling networks
-
A. Sodhi, S. Montaner, and J.S. Gutkind Viral hijacking of G-protein-coupled-receptor signalling networks Nat Rev Mol Cell Biol 5 2004 998 1012
-
(2004)
Nat Rev Mol Cell Biol
, vol.5
, pp. 998-1012
-
-
Sodhi, A.1
Montaner, S.2
Gutkind, J.S.3
-
14
-
-
34548763983
-
Virus-encoded G-protein-coupled receptors: Constitutively active (dys)regulators of cell function and their potential as drug target
-
H.F. Vischer, J.W. Hulshof, I.J. de Esch, M.J. Smit, and R. Leurs Virus-encoded G-protein-coupled receptors: constitutively active (dys)regulators of cell function and their potential as drug target Ernst Schering foundation symposium proceedings 2006 187 209
-
(2006)
Ernst Schering Foundation Symposium Proceedings
, pp. 187-209
-
-
Vischer, H.F.1
Hulshof, J.W.2
De Esch, I.J.3
Smit, M.J.4
Leurs, R.5
-
15
-
-
78650845707
-
G protein-coupled receptors: Novel targets for drug discovery in cancer
-
R. Lappano, and M. Maggiolini G protein-coupled receptors: novel targets for drug discovery in cancer Nat Rev Drug Discov 10 2011 47 60
-
(2011)
Nat Rev Drug Discov
, vol.10
, pp. 47-60
-
-
Lappano, R.1
Maggiolini, M.2
-
17
-
-
85013312416
-
Tumor angiogenesis: Therapeutic implications
-
J. Folkman Tumor angiogenesis: therapeutic implications N Engl J Med 285 1971 1182 1186
-
(1971)
N Engl J Med
, vol.285
, pp. 1182-1186
-
-
Folkman, J.1
-
18
-
-
0035952713
-
Angiogenesis and G-protein-coupled receptors: Signals that bridge the gap
-
D.E. Richard, V. Vouret-Craviari, and J. Pouyssegur Angiogenesis and G-protein-coupled receptors: signals that bridge the gap Oncogene 20 2001 1556 1562
-
(2001)
Oncogene
, vol.20
, pp. 1556-1562
-
-
Richard, D.E.1
Vouret-Craviari, V.2
Pouyssegur, J.3
-
19
-
-
44349100383
-
Organ selectivity in metastasis: Regulation by chemokines and their receptors
-
A. Ben-Baruch Organ selectivity in metastasis: regulation by chemokines and their receptors Clin Exp Metastasis 25 2008 345 356
-
(2008)
Clin Exp Metastasis
, vol.25
, pp. 345-356
-
-
Ben-Baruch, A.1
-
20
-
-
0029011084
-
G protein-coupled receptor systems involved in cell growth and oncogenesis
-
N. Dhanasekaran, L.E. Heasley, and G.L. Johnson G protein-coupled receptor systems involved in cell growth and oncogenesis Endocr Rev 16 1995 259 270
-
(1995)
Endocr Rev
, vol.16
, pp. 259-270
-
-
Dhanasekaran, N.1
Heasley, L.E.2
Johnson, G.L.3
-
21
-
-
0024404145
-
GTPase inhibiting mutations activate the alpha chain of Gs and stimulate adenylyl cyclase in human pituitary tumours
-
C.A. Landis, S.B. Masters, A. Spada, A.M. Pace, H.R. Bourne, and L. Vallar GTPase inhibiting mutations activate the alpha chain of Gs and stimulate adenylyl cyclase in human pituitary tumours Nature 340 1989 692 696
-
(1989)
Nature
, vol.340
, pp. 692-696
-
-
Landis, C.A.1
Masters, S.B.2
Spada, A.3
Pace, A.M.4
Bourne, H.R.5
Vallar, L.6
-
22
-
-
0024425826
-
Synthesis in Escherichia coli of GTPase-deficient mutants of Gs alpha
-
M.P. Graziano, and A.G. Gilman Synthesis in Escherichia coli of GTPase-deficient mutants of Gs alpha J Biol Chem 264 1989 15475 15482
-
(1989)
J Biol Chem
, vol.264
, pp. 15475-15482
-
-
Graziano, M.P.1
Gilman, A.G.2
-
23
-
-
0025285138
-
A new constitutively activating mutation of the Gs protein alpha subunit-gsp oncogene is found in human pituitary tumours
-
E. Clementi, N. Malgaretti, J. Meldolesi, and R. Taramelli A new constitutively activating mutation of the Gs protein alpha subunit-gsp oncogene is found in human pituitary tumours Oncogene 5 1990 1059 1061
-
(1990)
Oncogene
, vol.5
, pp. 1059-1061
-
-
Clementi, E.1
Malgaretti, N.2
Meldolesi, J.3
Taramelli, R.4
-
24
-
-
0026009016
-
Activating point mutations of the gsp oncogene in human thyroid adenomas
-
C. O'Sullivan, C.M. Barton, S.L. Staddon, C.L. Brown, and N.R. Lemoine Activating point mutations of the gsp oncogene in human thyroid adenomas Mol Carcinog 4 1991 345 349
-
(1991)
Mol Carcinog
, vol.4
, pp. 345-349
-
-
O'Sullivan, C.1
Barton, C.M.2
Staddon, S.L.3
Brown, C.L.4
Lemoine, N.R.5
-
25
-
-
0025865247
-
Gsp mutations in human thyroid tumours
-
H.G. Suarez, J.A. du Villard, B. Caillou, M. Schlumberger, C. Parmentier, and R. Monier gsp mutations in human thyroid tumours Oncogene 6 1991 677 679
-
(1991)
Oncogene
, vol.6
, pp. 677-679
-
-
Suarez, H.G.1
Du Villard, J.A.2
Caillou, B.3
Schlumberger, M.4
Parmentier, C.5
Monier, R.6
-
26
-
-
0026003074
-
Activating mutations of the stimulatory G protein in the McCune-Albright syndrome
-
L.S. Weinstein, A. Shenker, P.V. Gejman, M.J. Merino, E. Friedman, and A.M. Spiegel Activating mutations of the stimulatory G protein in the McCune-Albright syndrome N Engl J Med 325 1991 1688 1695
-
(1991)
N Engl J Med
, vol.325
, pp. 1688-1695
-
-
Weinstein, L.S.1
Shenker, A.2
Gejman, P.V.3
Merino, M.J.4
Friedman, E.5
Spiegel, A.M.6
-
27
-
-
0025127424
-
Two G protein oncogenes in human endocrine tumors
-
J. Lyons, C.A. Landis, G. Harsh, L. Vallar, K. Grunewald, and H. Feichtinger Two G protein oncogenes in human endocrine tumors Science 249 1990 655 659
-
(1990)
Science
, vol.249
, pp. 655-659
-
-
Lyons, J.1
Landis, C.A.2
Harsh, G.3
Vallar, L.4
Grunewald, K.5
Feichtinger, H.6
-
28
-
-
0026500077
-
Activation of phospholipase C by the alpha subunits of the Gq and G11 proteins in transfected Cos-7 cells
-
D.Q. Wu, C.H. Lee, S.G. Rhee, and M.I. Simon Activation of phospholipase C by the alpha subunits of the Gq and G11 proteins in transfected Cos-7 cells J Biol Chem 267 1992 1811 1817
-
(1992)
J Biol Chem
, vol.267
, pp. 1811-1817
-
-
Wu, D.Q.1
Lee, C.H.2
Rhee, S.G.3
Simon, M.I.4
-
29
-
-
0028180149
-
Expression of GTPase-deficient G alpha 16 inhibits Swiss 3T3 cell growth
-
N.X. Qian, M. Russell, A.M. Buhl, and G.L. Johnson Expression of GTPase-deficient G alpha 16 inhibits Swiss 3T3 cell growth J Biol Chem 269 1994 17417 17423
-
(1994)
J Biol Chem
, vol.269
, pp. 17417-17423
-
-
Qian, N.X.1
Russell, M.2
Buhl, A.M.3
Johnson, G.L.4
-
30
-
-
0026693669
-
Enhanced phospholipase C stimulation and transformation in NIH-3T3 cells expressing Q209LGq-Alpha-subunits
-
M. De Vivo, J. Chen, J. Codina, and R. Iyengar Enhanced phospholipase C stimulation and transformation in NIH-3T3 cells expressing Q209LGq-Alpha- subunits J Biol Chem 267 1992 18263 18266
-
(1992)
J Biol Chem
, vol.267
, pp. 18263-18266
-
-
De Vivo, M.1
Chen, J.2
Codina, J.3
Iyengar, R.4
-
31
-
-
0026725897
-
Mutated alpha subunit of the Gq protein induces malignant transformation in NIH 3T3 cells
-
G. Kalinec, A.J. Nazarali, S. Hermouet, N. Xu, and J.S. Gutkind Mutated alpha subunit of the Gq protein induces malignant transformation in NIH 3T3 cells Mol Cell Biol 12 1992 4687 4693
-
(1992)
Mol Cell Biol
, vol.12
, pp. 4687-4693
-
-
Kalinec, G.1
Nazarali, A.J.2
Hermouet, S.3
Xu, N.4
Gutkind, J.S.5
-
32
-
-
0027303269
-
The transforming activity of activated G alpha 12
-
H. Jiang, D. Wu, and M.I. Simon The transforming activity of activated G alpha 12 FEBS Lett 330 1993 319 322
-
(1993)
FEBS Lett
, vol.330
, pp. 319-322
-
-
Jiang, H.1
Wu, D.2
Simon, M.I.3
-
33
-
-
0028173803
-
Activated mutant of G alpha 13 induces Egr-1, c-fos, and transformation in NIH 3T3 cells
-
M.V. Vara Prasad, S.K. Shore, and N. Dhanasekaran Activated mutant of G alpha 13 induces Egr-1, c-fos, and transformation in NIH 3T3 cells Oncogene 9 1994 2425 2429
-
(1994)
Oncogene
, vol.9
, pp. 2425-2429
-
-
Vara Prasad, M.V.1
Shore, S.K.2
Dhanasekaran, N.3
-
34
-
-
0027217195
-
A mutant alpha subunit of G12 potentiates the eicosanoid pathway and is highly oncogenic in NIH 3T3 cells
-
N. Xu, L. Bradley, I. Ambdukar, and J.S. Gutkind A mutant alpha subunit of G12 potentiates the eicosanoid pathway and is highly oncogenic in NIH 3T3 cells Proc Natl Acad Sci USA 90 1993 6741 6745
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 6741-6745
-
-
Xu, N.1
Bradley, L.2
Ambdukar, I.3
Gutkind, J.S.4
-
35
-
-
0027497516
-
Expression cDNA cloning of a transforming gene encoding the wild-type G alpha 12 gene product
-
A.M. Chan, T.P. Fleming, E.S. McGovern, M. Chedid, T. Miki, and S.A. Aaronson Expression cDNA cloning of a transforming gene encoding the wild-type G alpha 12 gene product Mol Cell Biol 13 1993 762 768
-
(1993)
Mol Cell Biol
, vol.13
, pp. 762-768
-
-
Chan, A.M.1
Fleming, T.P.2
McGovern, E.S.3
Chedid, M.4
Miki, T.5
Aaronson, S.A.6
-
36
-
-
33645740350
-
The G12/13-RhoA signaling pathway contributes to efficient lysophosphatidic acid-stimulated cell migration
-
D. Bian, C. Mahanivong, J. Yu, S.M. Frisch, Z.K. Pan, and R.D. Ye The G12/13-RhoA signaling pathway contributes to efficient lysophosphatidic acid-stimulated cell migration Oncogene 25 2006 2234 2244
-
(2006)
Oncogene
, vol.25
, pp. 2234-2244
-
-
Bian, D.1
Mahanivong, C.2
Yu, J.3
Frisch, S.M.4
Pan, Z.K.5
Ye, R.D.6
-
37
-
-
77950254571
-
Inhibition of tumor growth and angiogenesis by a lysophosphatidic acid antagonist in an engineered three-dimensional lung cancer xenograft model
-
X. Xu, and G.D. Prestwich Inhibition of tumor growth and angiogenesis by a lysophosphatidic acid antagonist in an engineered three-dimensional lung cancer xenograft model Cancer 116 2010 1739 1750
-
(2010)
Cancer
, vol.116
, pp. 1739-1750
-
-
Xu, X.1
Prestwich, G.D.2
-
38
-
-
0031927754
-
Thrombin receptor overexpression in malignant and physiological invasion processes
-
S. Even-Ram, B. Uziely, P. Cohen, S. Grisaru-Granovsky, M. Maoz, and Y. Ginzburg Thrombin receptor overexpression in malignant and physiological invasion processes Nat Med 4 1998 909 914
-
(1998)
Nat Med
, vol.4
, pp. 909-914
-
-
Even-Ram, S.1
Uziely, B.2
Cohen, P.3
Grisaru-Granovsky, S.4
Maoz, M.5
Ginzburg, Y.6
-
39
-
-
0037024697
-
Galpha12 and Galpha13 negatively regulate the adhesive functions of cadherin
-
T.E. Meigs, M. Fedor-Chaiken, D.D. Kaplan, R. Brackenbury, and P.J. Casey Galpha12 and Galpha13 negatively regulate the adhesive functions of cadherin J Biol Chem 277 2002 24594 24600
-
(2002)
J Biol Chem
, vol.277
, pp. 24594-24600
-
-
Meigs, T.E.1
Fedor-Chaiken, M.2
Kaplan, D.D.3
Brackenbury, R.4
Casey, P.J.5
-
40
-
-
0034282388
-
Nonhypoxic pathway mediates the induction of hypoxia-inducible factor 1alpha in vascular smooth muscle cells
-
D.E. Richard, E. Berra, and J. Pouyssegur Nonhypoxic pathway mediates the induction of hypoxia-inducible factor 1alpha in vascular smooth muscle cells J Biol Chem 275 2000 26765 26771
-
(2000)
J Biol Chem
, vol.275
, pp. 26765-26771
-
-
Richard, D.E.1
Berra, E.2
Pouyssegur, J.3
-
41
-
-
0029061789
-
Angiotensin II increases vascular permeability factor gene expression by human vascular smooth muscle cells
-
B. Williams, A.Q. Baker, B. Gallacher, and D. Lodwick Angiotensin II increases vascular permeability factor gene expression by human vascular smooth muscle cells Hypertension 25 1995 913 917
-
(1995)
Hypertension
, vol.25
, pp. 913-917
-
-
Williams, B.1
Baker, A.Q.2
Gallacher, B.3
Lodwick, D.4
-
42
-
-
22344431893
-
Palmitoylation regulates plasma membrane-nuclear shuttling of R7BP, a novel membrane anchor for the RGS7 family
-
R.M. Drenan, C.A. Doupnik, M.P. Boyle, L.J. Muglia, J.E. Huettner, and M.E. Linder Palmitoylation regulates plasma membrane-nuclear shuttling of R7BP, a novel membrane anchor for the RGS7 family J Cell Biol 169 2005 623 633
-
(2005)
J Cell Biol
, vol.169
, pp. 623-633
-
-
Drenan, R.M.1
Doupnik, C.A.2
Boyle, M.P.3
Muglia, L.J.4
Huettner, J.E.5
Linder, M.E.6
-
43
-
-
22344454972
-
G protein beta interacts with the glucocorticoid receptor and suppresses its transcriptional activity in the nucleus
-
T. Kino, A. Tiulpakov, T. Ichijo, L. Chheng, T. Kozasa, and G.P. Chrousos G protein beta interacts with the glucocorticoid receptor and suppresses its transcriptional activity in the nucleus J Cell Biol 169 2005 885 896
-
(2005)
J Cell Biol
, vol.169
, pp. 885-896
-
-
Kino, T.1
Tiulpakov, A.2
Ichijo, T.3
Chheng, L.4
Kozasa, T.5
Chrousos, G.P.6
-
44
-
-
0033565641
-
Transcriptional regulation by the gamma5 subunit of a heterotrimeric G protein during adipogenesis
-
J.G. Park, A. Muise, G.P. He, S.W. Kim, and H.S. Ro Transcriptional regulation by the gamma5 subunit of a heterotrimeric G protein during adipogenesis EMBO J 18 1999 4004 4012
-
(1999)
EMBO J
, vol.18
, pp. 4004-4012
-
-
Park, J.G.1
Muise, A.2
He, G.P.3
Kim, S.W.4
Ro, H.S.5
-
45
-
-
29244473549
-
G betagamma binds histone deacetylase 5 (HDAC5) and inhibits its transcriptional co-repression activity
-
B.D. Spiegelberg, and H.E. Hamm G betagamma binds histone deacetylase 5 (HDAC5) and inhibits its transcriptional co-repression activity J Biol Chem 280 2005 41769 41776
-
(2005)
J Biol Chem
, vol.280
, pp. 41769-41776
-
-
Spiegelberg, B.D.1
Hamm, H.E.2
-
46
-
-
70349473057
-
Regulator of G-protein signaling (RGS) proteins in cancer biology
-
J.H. Hurst, and S.B. Hooks Regulator of G-protein signaling (RGS) proteins in cancer biology Biochem Pharmacol 78 2009 1289 1297
-
(2009)
Biochem Pharmacol
, vol.78
, pp. 1289-1297
-
-
Hurst, J.H.1
Hooks, S.B.2
-
47
-
-
58349108702
-
Modulation of g protein signaling normalizes tumor vessels
-
M. Manzur, J. Hamzah, and R. Ganss Modulation of g protein signaling normalizes tumor vessels Cancer Res 69 2009 396 399
-
(2009)
Cancer Res
, vol.69
, pp. 396-399
-
-
Manzur, M.1
Hamzah, J.2
Ganss, R.3
-
48
-
-
19644373254
-
Wnt signaling in disease and in development
-
R. Nusse Wnt signaling in disease and in development Cell Res 15 2005 28 32
-
(2005)
Cell Res
, vol.15
, pp. 28-32
-
-
Nusse, R.1
-
49
-
-
0025941471
-
Identification of deletion mutations and three new genes at the familial polyposis locus
-
G. Joslyn, M. Carlson, A. Thliveris, H. Albertsen, L. Gelbert, and W. Samowitz Identification of deletion mutations and three new genes at the familial polyposis locus Cell 66 1991 601 613
-
(1991)
Cell
, vol.66
, pp. 601-613
-
-
Joslyn, G.1
Carlson, M.2
Thliveris, A.3
Albertsen, H.4
Gelbert, L.5
Samowitz, W.6
-
50
-
-
0025899162
-
Mutations of chromosome 5q21 genes in FAP and colorectal cancer patients
-
I. Nishisho, Y. Nakamura, Y. Miyoshi, Y. Miki, H. Ando, and A. Horii Mutations of chromosome 5q21 genes in FAP and colorectal cancer patients Science 253 1991 665 669
-
(1991)
Science
, vol.253
, pp. 665-669
-
-
Nishisho, I.1
Nakamura, Y.2
Miyoshi, Y.3
Miki, Y.4
Ando, H.5
Horii, A.6
-
51
-
-
5444265502
-
The Wnt connection to tumorigenesis
-
J. Behrens, and B. Lustig The Wnt connection to tumorigenesis Int J Dev Biol 48 2004 477 487
-
(2004)
Int J Dev Biol
, vol.48
, pp. 477-487
-
-
Behrens, J.1
Lustig, B.2
-
52
-
-
76849085038
-
MSX1 induces the Wnt pathway antagonist genes DKK1, DKK2, DKK3, and SFRP1 in neuroblastoma cells, but does not block Wnt3 and Wnt5A signalling to DVL3
-
I. Revet, G. Huizenga, J. Koster, R. Volckmann, P. van Sluis, and R. Versteeg MSX1 induces the Wnt pathway antagonist genes DKK1, DKK2, DKK3, and SFRP1 in neuroblastoma cells, but does not block Wnt3 and Wnt5A signalling to DVL3 Cancer Lett 289 2010 195 207
-
(2010)
Cancer Lett
, vol.289
, pp. 195-207
-
-
Revet, I.1
Huizenga, G.2
Koster, J.3
Volckmann, R.4
Van Sluis, P.5
Versteeg, R.6
-
53
-
-
33644967242
-
Wnt signaling: Complexity at the surface
-
K.M. Cadigan, and Y.I. Liu Wnt signaling: complexity at the surface J Cell Sci 119 2006 395 402
-
(2006)
J Cell Sci
, vol.119
, pp. 395-402
-
-
Cadigan, K.M.1
Liu, Y.I.2
-
54
-
-
34147105513
-
Frizzled-7 dictates three-dimensional organization of colorectal cancer cell carcinoids
-
E. Vincan, P.K. Darcy, C.A. Farrelly, M.C. Faux, T. Brabletz, and R.G. Ramsay Frizzled-7 dictates three-dimensional organization of colorectal cancer cell carcinoids Oncogene 26 2007 2340 2352
-
(2007)
Oncogene
, vol.26
, pp. 2340-2352
-
-
Vincan, E.1
Darcy, P.K.2
Farrelly, C.A.3
Faux, M.C.4
Brabletz, T.5
Ramsay, R.G.6
-
55
-
-
78650484935
-
Wnt signaling requires sequestration of glycogen synthase kinase 3 inside multivesicular endosomes
-
V.F. Taelman, R. Dobrowolski, J.L. Plouhinec, L.C. Fuentealba, P.P. Vorwald, and I. Gumper Wnt signaling requires sequestration of glycogen synthase kinase 3 inside multivesicular endosomes Cell 143 2010 1136 1148
-
(2010)
Cell
, vol.143
, pp. 1136-1148
-
-
Taelman, V.F.1
Dobrowolski, R.2
Plouhinec, J.L.3
Fuentealba, L.C.4
Vorwald, P.P.5
Gumper, I.6
-
56
-
-
84862617605
-
Wnt/beta-catenin signaling regulates telomerase in stem cells and cancer cells
-
K. Hoffmeyer, A. Raggioli, S. Rudloff, R. Anton, A. Hierholzer, and I. Del Valle Wnt/beta-catenin signaling regulates telomerase in stem cells and cancer cells Science 336 2012 1549 1554
-
(2012)
Science
, vol.336
, pp. 1549-1554
-
-
Hoffmeyer, K.1
Raggioli, A.2
Rudloff, S.3
Anton, R.4
Hierholzer, A.5
Del Valle, I.6
-
57
-
-
32444449871
-
GLI transcription factors: Mediators of oncogenic Hedgehog signalling
-
M. Kasper, G. Regl, A.M. Frischauf, and F. Aberger GLI transcription factors: mediators of oncogenic Hedgehog signalling Eur J Cancer 42 2006 437 445
-
(2006)
Eur J Cancer
, vol.42
, pp. 437-445
-
-
Kasper, M.1
Regl, G.2
Frischauf, A.M.3
Aberger, F.4
-
58
-
-
70350534843
-
Hedgehog target genes: Mechanisms of carcinogenesis induced by aberrant hedgehog signaling activation
-
Y. Katoh, and M. Katoh Hedgehog target genes: mechanisms of carcinogenesis induced by aberrant hedgehog signaling activation Curr Mol Med 9 2009 873 886
-
(2009)
Curr Mol Med
, vol.9
, pp. 873-886
-
-
Katoh, Y.1
Katoh, M.2
-
59
-
-
57049089995
-
Hedgehog signaling in development and cancer
-
J. Jiang, and C.C. Hui Hedgehog signaling in development and cancer Dev Cell 15 2008 801 812
-
(2008)
Dev Cell
, vol.15
, pp. 801-812
-
-
Jiang, J.1
Hui, C.C.2
-
60
-
-
2942738996
-
The Hedgehog response network: Sensors, switches, and routers
-
L. Lum, and P.A. Beachy The Hedgehog response network: sensors, switches, and routers Science 304 2004 1755 1759
-
(2004)
Science
, vol.304
, pp. 1755-1759
-
-
Lum, L.1
Beachy, P.A.2
-
61
-
-
0034213071
-
LNB-TM7, a group of seven-transmembrane proteins related to family-B G-protein-coupled receptors
-
M. Stacey, H.H. Lin, S. Gordon, and A.J. McKnight LNB-TM7, a group of seven-transmembrane proteins related to family-B G-protein-coupled receptors Trends Biochem Sci 25 2000 284 289
-
(2000)
Trends Biochem Sci
, vol.25
, pp. 284-289
-
-
Stacey, M.1
Lin, H.H.2
Gordon, S.3
McKnight, A.J.4
-
62
-
-
53149135394
-
Adhesion-GPCRs: Emerging roles for novel receptors
-
S. Yona, H.H. Lin, W.O. Siu, S. Gordon, and M. Stacey Adhesion-GPCRs: emerging roles for novel receptors Trends Biochem Sci 33 2008 491 500
-
(2008)
Trends Biochem Sci
, vol.33
, pp. 491-500
-
-
Yona, S.1
Lin, H.H.2
Siu, W.O.3
Gordon, S.4
Stacey, M.5
-
63
-
-
0038642821
-
Proteolytic cleavage of the EMR2 receptor requires both the extracellular stalk and the GPS motif
-
G.W. Chang, M. Stacey, M.J. Kwakkenbos, J. Hamann, S. Gordon, and H.H. Lin Proteolytic cleavage of the EMR2 receptor requires both the extracellular stalk and the GPS motif FEBS Lett 547 2003 145 150
-
(2003)
FEBS Lett
, vol.547
, pp. 145-150
-
-
Chang, G.W.1
Stacey, M.2
Kwakkenbos, M.J.3
Hamann, J.4
Gordon, S.5
Lin, H.H.6
-
64
-
-
0037195853
-
Post-translational proteolytic processing of the calcium-independent receptor of alpha-latrotoxin (CIRL), a natural chimera of the cell adhesion protein and the G protein-coupled receptor. Role of the G protein-coupled receptor proteolysis site (GPS) motif
-
V. Krasnoperov, Y. Lu, L. Buryanovsky, T.A. Neubert, K. Ichtchenko, and A.G. Petrenko Post-translational proteolytic processing of the calcium-independent receptor of alpha-latrotoxin (CIRL), a natural chimera of the cell adhesion protein and the G protein-coupled receptor. Role of the G protein-coupled receptor proteolysis site (GPS) motif J Biol Chem 277 2002 46518 46526
-
(2002)
J Biol Chem
, vol.277
, pp. 46518-46526
-
-
Krasnoperov, V.1
Lu, Y.2
Buryanovsky, L.3
Neubert, T.A.4
Ichtchenko, K.5
Petrenko, A.G.6
-
65
-
-
3843101589
-
Autocatalytic cleavage of the EMR2 receptor occurs at a conserved G protein-coupled receptor proteolytic site motif
-
H.H. Lin, G.W. Chang, J.Q. Davies, M. Stacey, J. Harris, and S. Gordon Autocatalytic cleavage of the EMR2 receptor occurs at a conserved G protein-coupled receptor proteolytic site motif J Biol Chem 279 2004 31823 31832
-
(2004)
J Biol Chem
, vol.279
, pp. 31823-31832
-
-
Lin, H.H.1
Chang, G.W.2
Davies, J.Q.3
Stacey, M.4
Harris, J.5
Gordon, S.6
-
66
-
-
0036834440
-
CD97, but not its closely related EGF-TM7 family member EMR2, is expressed on gastric, pancreatic, and esophageal carcinomas
-
G. Aust, M. Steinert, A. Schutz, C. Boltze, M. Wahlbuhl, and J. Hamann CD97, but not its closely related EGF-TM7 family member EMR2, is expressed on gastric, pancreatic, and esophageal carcinomas Am J Clin Pathol 118 2002 699 707
-
(2002)
Am J Clin Pathol
, vol.118
, pp. 699-707
-
-
Aust, G.1
Steinert, M.2
Schutz, A.3
Boltze, C.4
Wahlbuhl, M.5
Hamann, J.6
-
67
-
-
15944418189
-
CD97, an adhesion receptor on inflammatory cells, stimulates angiogenesis through binding integrin counterreceptors on endothelial cells
-
T. Wang, Y. Ward, L. Tian, R. Lake, L. Guedez, and W.G. Stetler-Stevenson CD97, an adhesion receptor on inflammatory cells, stimulates angiogenesis through binding integrin counterreceptors on endothelial cells Blood 105 2005 2836 2844
-
(2005)
Blood
, vol.105
, pp. 2836-2844
-
-
Wang, T.1
Ward, Y.2
Tian, L.3
Lake, R.4
Guedez, L.5
Stetler-Stevenson, W.G.6
-
68
-
-
19944433843
-
Expression of the epidermal growth factor seven-transmembrane member CD97 correlates with grading and staging in human oral squamous cell carcinomas
-
T. Mustafa, A. Eckert, T. Klonisch, A. Kehlen, P. Maurer, and M. Klintschar Expression of the epidermal growth factor seven-transmembrane member CD97 correlates with grading and staging in human oral squamous cell carcinomas Cancer Epidemiol Biomarkers Prev 14 2005 108 119
-
(2005)
Cancer Epidemiol Biomarkers Prev
, vol.14
, pp. 108-119
-
-
Mustafa, T.1
Eckert, A.2
Klonisch, T.3
Kehlen, A.4
Maurer, P.5
Klintschar, M.6
-
69
-
-
82655171586
-
LPA receptor heterodimerizes with CD97 to amplify LPA-initiated RHO-dependent signaling and invasion in prostate cancer cells
-
Y. Ward, R. Lake, J.J. Yin, C.D. Heger, M. Raffeld, and P.K. Goldsmith LPA receptor heterodimerizes with CD97 to amplify LPA-initiated RHO-dependent signaling and invasion in prostate cancer cells Cancer Res 71 2011 7301 7311
-
(2011)
Cancer Res
, vol.71
, pp. 7301-7311
-
-
Ward, Y.1
Lake, R.2
Yin, J.J.3
Heger, C.D.4
Raffeld, M.5
Goldsmith, P.K.6
-
70
-
-
9844261161
-
A novel brain-specific p53-target gene, BAI1, containing thrombospondin type 1 repeats inhibits experimental angiogenesis
-
H. Nishimori, T. Shiratsuchi, T. Urano, Y. Kimura, K. Kiyono, and K. Tatsumi A novel brain-specific p53-target gene, BAI1, containing thrombospondin type 1 repeats inhibits experimental angiogenesis Oncogene 15 1997 2145 2150
-
(1997)
Oncogene
, vol.15
, pp. 2145-2150
-
-
Nishimori, H.1
Shiratsuchi, T.2
Urano, T.3
Kimura, Y.4
Kiyono, K.5
Tatsumi, K.6
-
71
-
-
13144294987
-
Brain-specific angiogenesis inhibitor 1 expression is inversely correlated with vascularity and distant metastasis of colorectal cancer
-
Y. Fukushima, Y. Oshika, T. Tsuchida, T. Tokunaga, H. Hatanaka, and H. Kijima Brain-specific angiogenesis inhibitor 1 expression is inversely correlated with vascularity and distant metastasis of colorectal cancer Int J Oncol 13 1998 967 970
-
(1998)
Int J Oncol
, vol.13
, pp. 967-970
-
-
Fukushima, Y.1
Oshika, Y.2
Tsuchida, T.3
Tokunaga, T.4
Hatanaka, H.5
Kijima, H.6
-
72
-
-
80051688309
-
GPR56 Regulates VEGF production and angiogenesis during melanoma progression
-
L. Yang, G. Chen, S. Mohanty, G. Scott, F. Fazal, and A. Rahman GPR56 Regulates VEGF production and angiogenesis during melanoma progression Cancer Res 71 2011 5558 5568
-
(2011)
Cancer Res
, vol.71
, pp. 5558-5568
-
-
Yang, L.1
Chen, G.2
Mohanty, S.3
Scott, G.4
Fazal, F.5
Rahman, A.6
-
73
-
-
14944362292
-
GPR56 is a GPCR that is overexpressed in gliomas and functions in tumor cell adhesion
-
S. Shashidhar, G. Lorente, U. Nagavarapu, A. Nelson, J. Kuo, and J. Cummins GPR56 is a GPCR that is overexpressed in gliomas and functions in tumor cell adhesion Oncogene 24 2005 1673 1682
-
(2005)
Oncogene
, vol.24
, pp. 1673-1682
-
-
Shashidhar, S.1
Lorente, G.2
Nagavarapu, U.3
Nelson, A.4
Kuo, J.5
Cummins, J.6
-
74
-
-
77649118968
-
Orphan receptor GPR110, an oncogene overexpressed in lung and prostate cancer
-
A.M. Lum, B.B. Wang, G.B. Beck-Engeser, L. Li, N. Channa, and M. Wabl Orphan receptor GPR110, an oncogene overexpressed in lung and prostate cancer BMC Cancer 10 2010 40
-
(2010)
BMC Cancer
, vol.10
, pp. 40
-
-
Lum, A.M.1
Wang, B.B.2
Beck-Engeser, G.B.3
Li, L.4
Channa, N.5
Wabl, M.6
-
75
-
-
0035884593
-
Cell surface tumor endothelial markers are conserved in mice and humans
-
E.B. Carson-Walter, D.N. Watkins, A. Nanda, B. Vogelstein, K.W. Kinzler, and B. St Croix Cell surface tumor endothelial markers are conserved in mice and humans Cancer Res 61 2001 6649 6655
-
(2001)
Cancer Res
, vol.61
, pp. 6649-6655
-
-
Carson-Walter, E.B.1
Watkins, D.N.2
Nanda, A.3
Vogelstein, B.4
Kinzler, K.W.5
St Croix, B.6
-
76
-
-
0035146135
-
Transactivation: A novel signaling pathway from angiotensin II to tyrosine kinase receptors
-
Y. Saito, and B.C. Berk Transactivation: a novel signaling pathway from angiotensin II to tyrosine kinase receptors J Mol Cell Cardiol 33 2001 3 7
-
(2001)
J Mol Cell Cardiol
, vol.33
, pp. 3-7
-
-
Saito, Y.1
Berk, B.C.2
-
77
-
-
0028240869
-
Ras-dependent activation of MAP kinase pathway mediated by G-protein beta gamma subunits
-
P. Crespo, N. Xu, W.F. Simonds, and J.S. Gutkind Ras-dependent activation of MAP kinase pathway mediated by G-protein beta gamma subunits Nature 369 1994 418 420
-
(1994)
Nature
, vol.369
, pp. 418-420
-
-
Crespo, P.1
Xu, N.2
Simonds, W.F.3
Gutkind, J.S.4
-
78
-
-
0028176297
-
CAMP and beta gamma subunits of heterotrimeric G proteins stimulate the mitogen-Activated protein kinase pathway in COS-7 cells
-
M. Faure, T.A. Voyno-Yasenetskaya, and H.R. Bourne cAMP and beta gamma subunits of heterotrimeric G proteins stimulate the mitogen-Activated protein kinase pathway in COS-7 cells J Biol Chem 269 1994 7851 7854
-
(1994)
J Biol Chem
, vol.269
, pp. 7851-7854
-
-
Faure, M.1
Voyno-Yasenetskaya, T.A.2
Bourne, H.R.3
-
79
-
-
0028670476
-
Direct evidence that Gi-coupled receptor stimulation of mitogen-Activated protein kinase is mediated by G beta gamma activation of p21ras
-
W.J. Koch, B.E. Hawes, L.F. Allen, and R.J. Lefkowitz Direct evidence that Gi-coupled receptor stimulation of mitogen-Activated protein kinase is mediated by G beta gamma activation of p21ras Proc Natl Acad Sci USA 91 1994 12706 12710
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 12706-12710
-
-
Koch, W.J.1
Hawes, B.E.2
Allen, L.F.3
Lefkowitz, R.J.4
-
80
-
-
0028564917
-
Mapping of the C5a receptor signal transduction network in human neutrophils
-
A.M. Buhl, N. Avdi, G.S. Worthen, and G.L. Johnson Mapping of the C5a receptor signal transduction network in human neutrophils Proc Natl Acad Sci USA 91 1994 9190 9194
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 9190-9194
-
-
Buhl, A.M.1
Avdi, N.2
Worthen, G.S.3
Johnson, G.L.4
-
81
-
-
0027930914
-
FMLP activates Ras and Raf in human neutrophils. Potential role in activation of MAP kinase
-
G.S. Worthen, N. Avdi, A.M. Buhl, N. Suzuki, and G.L. Johnson FMLP activates Ras and Raf in human neutrophils. Potential role in activation of MAP kinase J Clin Invest 94 1994 815 823
-
(1994)
J Clin Invest
, vol.94
, pp. 815-823
-
-
Worthen, G.S.1
Avdi, N.2
Buhl, A.M.3
Suzuki, N.4
Johnson, G.L.5
-
82
-
-
0027340385
-
Gi-mediated activation of the p21ras-mitogen-Activated protein kinase pathway by alpha 2-Adrenergic receptors expressed in fibroblasts
-
J. Alblas, E.J. van Corven, P.L. Hordijk, G. Milligan, and W.H. Moolenaar Gi-mediated activation of the p21ras-mitogen-Activated protein kinase pathway by alpha 2-Adrenergic receptors expressed in fibroblasts J Biol Chem 268 1993 22235 22238
-
(1993)
J Biol Chem
, vol.268
, pp. 22235-22238
-
-
Alblas, J.1
Van Corven, E.J.2
Hordijk, P.L.3
Milligan, G.4
Moolenaar, W.H.5
-
83
-
-
0027240231
-
Involvement of Ras and Raf in the Gi-coupled acetylcholine muscarinic m2 receptor activation of mitogen-Activated protein (MAP) kinase kinase and MAP kinase
-
S. Winitz, M. Russell, N.X. Qian, A. Gardner, L. Dwyer, and G.L. Johnson Involvement of Ras and Raf in the Gi-coupled acetylcholine muscarinic m2 receptor activation of mitogen-Activated protein (MAP) kinase kinase and MAP kinase J Biol Chem 268 1993 19196 19199
-
(1993)
J Biol Chem
, vol.268
, pp. 19196-19199
-
-
Winitz, S.1
Russell, M.2
Qian, N.X.3
Gardner, A.4
Dwyer, L.5
Johnson, G.L.6
-
84
-
-
0027432825
-
Lysophosphatidic acid stimulates mitogen-Activated protein kinase activation via a G-protein-coupled pathway requiring p21ras and p74raf-1
-
L.R. Howe, and C.J. Marshall Lysophosphatidic acid stimulates mitogen-Activated protein kinase activation via a G-protein-coupled pathway requiring p21ras and p74raf-1 J Biol Chem 268 1993 20717 20720
-
(1993)
J Biol Chem
, vol.268
, pp. 20717-20720
-
-
Howe, L.R.1
Marshall, C.J.2
-
85
-
-
0027411213
-
Pertussis toxin-sensitive activation of p21ras by G protein-coupled receptor agonists in fibroblasts
-
E.J. van Corven, P.L. Hordijk, R.H. Medema, J.L. Bos, and W.H. Moolenaar Pertussis toxin-sensitive activation of p21ras by G protein-coupled receptor agonists in fibroblasts Proc Natl Acad Sci USA 90 1993 1257 1261
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 1257-1261
-
-
Van Corven, E.J.1
Hordijk, P.L.2
Medema, R.H.3
Bos, J.L.4
Moolenaar, W.H.5
-
86
-
-
0028296444
-
Suppression of Ras-induced transformation of NIH 3T3 cells by activated G alpha s
-
J. Chen, and R. Iyengar Suppression of Ras-induced transformation of NIH 3T3 cells by activated G alpha s Science 263 1994 1278 1281
-
(1994)
Science
, vol.263
, pp. 1278-1281
-
-
Chen, J.1
Iyengar, R.2
-
87
-
-
0028982948
-
Distinct pathways of Gi- and Gq-mediated mitogen-Activated protein kinase activation
-
B.E. Hawes, T. van Biesen, W.J. Koch, L.M. Luttrell, and R.J. Lefkowitz Distinct pathways of Gi- and Gq-mediated mitogen-Activated protein kinase activation J Biol Chem 270 1995 17148 17153
-
(1995)
J Biol Chem
, vol.270
, pp. 17148-17153
-
-
Hawes, B.E.1
Van Biesen, T.2
Koch, W.J.3
Luttrell, L.M.4
Lefkowitz, R.J.5
-
88
-
-
0028977847
-
Receptor-tyrosine-kinase- and G beta gamma-mediated MAP kinase activation by a common signalling pathway
-
T. van Biesen, B.E. Hawes, D.K. Luttrell, K.M. Krueger, K. Touhara, and E. Porfiri Receptor-tyrosine-kinase- and G beta gamma-mediated MAP kinase activation by a common signalling pathway Nature 376 1995 781 784
-
(1995)
Nature
, vol.376
, pp. 781-784
-
-
Van Biesen, T.1
Hawes, B.E.2
Luttrell, D.K.3
Krueger, K.M.4
Touhara, K.5
Porfiri, E.6
-
89
-
-
0030044360
-
Role of transactivation of the EGF receptor in signalling by G-protein-coupled receptors
-
H. Daub, F.U. Weiss, C. Wallasch, and A. Ullrich Role of transactivation of the EGF receptor in signalling by G-protein-coupled receptors Nature 379 1996 557 560
-
(1996)
Nature
, vol.379
, pp. 557-560
-
-
Daub, H.1
Weiss, F.U.2
Wallasch, C.3
Ullrich, A.4
-
90
-
-
38449087529
-
Crosstalk between G-protein-coupled receptors and epidermal growth factor receptor in cancer
-
N.E. Bhola, and J.R. Grandis Crosstalk between G-protein-coupled receptors and epidermal growth factor receptor in cancer Front Biosci 13 2008 1857 1865
-
(2008)
Front Biosci
, vol.13
, pp. 1857-1865
-
-
Bhola, N.E.1
Grandis, J.R.2
-
91
-
-
0033599039
-
EGF receptor transactivation by G-protein-coupled receptors requires metalloproteinase cleavage of proHB-EGF
-
N. Prenzel, E. Zwick, H. Daub, M. Leserer, R. Abraham, and C. Wallasch EGF receptor transactivation by G-protein-coupled receptors requires metalloproteinase cleavage of proHB-EGF Nature 402 1999 884 888
-
(1999)
Nature
, vol.402
, pp. 884-888
-
-
Prenzel, N.1
Zwick, E.2
Daub, H.3
Leserer, M.4
Abraham, R.5
Wallasch, C.6
-
92
-
-
0032502765
-
Calcium-dependent epidermal growth factor receptor transactivation mediates the angiotensin II-induced mitogen-Activated protein kinase activation in vascular smooth muscle cells
-
S. Eguchi, K. Numaguchi, H. Iwasaki, T. Matsumoto, T. Yamakawa, and H. Utsunomiya Calcium-dependent epidermal growth factor receptor transactivation mediates the angiotensin II-induced mitogen-Activated protein kinase activation in vascular smooth muscle cells J Biol Chem 273 1998 8890 8896
-
(1998)
J Biol Chem
, vol.273
, pp. 8890-8896
-
-
Eguchi, S.1
Numaguchi, K.2
Iwasaki, H.3
Matsumoto, T.4
Yamakawa, T.5
Utsunomiya, H.6
-
93
-
-
46849101053
-
Vasopressin up-regulates the expression of growth-related immediate-early genes via two distinct EGF receptor transactivation pathways
-
L.Q. Fuentes, C.E. Reyes, J.M. Sarmiento, C.I. Villanueva, C.D. Figueroa, and J. Navarro Vasopressin up-regulates the expression of growth-related immediate-early genes via two distinct EGF receptor transactivation pathways Cell Signal 20 2008 1642 1650
-
(2008)
Cell Signal
, vol.20
, pp. 1642-1650
-
-
Fuentes, L.Q.1
Reyes, C.E.2
Sarmiento, J.M.3
Villanueva, C.I.4
Figueroa, C.D.5
Navarro, J.6
-
94
-
-
0034737483
-
The beta(2)-Adrenergic receptor mediates extracellular signal-regulated kinase activation via assembly of a multi-receptor complex with the epidermal growth factor receptor
-
S. Maudsley, K.L. Pierce, A.M. Zamah, W.E. Miller, S. Ahn, and Y. Daaka The beta(2)-Adrenergic receptor mediates extracellular signal-regulated kinase activation via assembly of a multi-receptor complex with the epidermal growth factor receptor J Biol Chem 275 2000 9572 9580
-
(2000)
J Biol Chem
, vol.275
, pp. 9572-9580
-
-
Maudsley, S.1
Pierce, K.L.2
Zamah, A.M.3
Miller, W.E.4
Ahn, S.5
Daaka, Y.6
-
95
-
-
67749139960
-
Beta-Arrestin mediates beta1-Adrenergic receptor-epidermal growth factor receptor interaction and downstream signaling
-
D.G. Tilley, I.M. Kim, P.A. Patel, J.D. Violin, and H.A. Rockman beta-Arrestin mediates beta1-Adrenergic receptor-epidermal growth factor receptor interaction and downstream signaling J Biol Chem 284 2009 20375 20386
-
(2009)
J Biol Chem
, vol.284
, pp. 20375-20386
-
-
Tilley, D.G.1
Kim, I.M.2
Patel, P.A.3
Violin, J.D.4
Rockman, H.A.5
-
96
-
-
79959610178
-
GPR54 (KISS1R) transactivates EGFR to promote breast cancer cell invasiveness
-
M. Zajac, J. Law, D.D. Cvetkovic, M. Pampillo, L. McColl, and C. Pape GPR54 (KISS1R) transactivates EGFR to promote breast cancer cell invasiveness PLoS One 6 2011 e21599
-
(2011)
PLoS One
, vol.6
, pp. 21599
-
-
Zajac, M.1
Law, J.2
Cvetkovic, D.D.3
Pampillo, M.4
McColl, L.5
Pape, C.6
-
97
-
-
1342322686
-
Multiple G-protein-coupled receptor signals converge on the epidermal growth factor receptor to promote migration and invasion
-
B. Schafer, A. Gschwind, and A. Ullrich Multiple G-protein-coupled receptor signals converge on the epidermal growth factor receptor to promote migration and invasion Oncogene 23 2004 991 999
-
(2004)
Oncogene
, vol.23
, pp. 991-999
-
-
Schafer, B.1
Gschwind, A.2
Ullrich, A.3
-
98
-
-
0033780783
-
Estrogen-induced activation of Erk-1 and Erk-2 requires the G protein-coupled receptor homolog, GPR30, and occurs via trans-Activation of the epidermal growth factor receptor through release of HB-EGF
-
E.J. Filardo, J.A. Quinn, K.I. Bland, and A.R. Frackelton Jr. Estrogen-induced activation of Erk-1 and Erk-2 requires the G protein-coupled receptor homolog, GPR30, and occurs via trans-Activation of the epidermal growth factor receptor through release of HB-EGF Mol Endocrinol 14 2000 1649 1660
-
(2000)
Mol Endocrinol
, vol.14
, pp. 1649-1660
-
-
Filardo, E.J.1
Quinn, J.A.2
Bland, K.I.3
Frackelton, Jr.A.R.4
-
99
-
-
33847755409
-
G protein-coupled receptor 30 (GPR30) mediates gene expression changes and growth response to 17beta-estradiol and selective GPR30 ligand G-1 in ovarian cancer cells
-
L. Albanito, A. Madeo, R. Lappano, A. Vivacqua, V. Rago, and A. Carpino G protein-coupled receptor 30 (GPR30) mediates gene expression changes and growth response to 17beta-estradiol and selective GPR30 ligand G-1 in ovarian cancer cells Cancer Res 67 2007 1859 1866
-
(2007)
Cancer Res
, vol.67
, pp. 1859-1866
-
-
Albanito, L.1
Madeo, A.2
Lappano, R.3
Vivacqua, A.4
Rago, V.5
Carpino, A.6
-
100
-
-
77955711650
-
Activation of GPR30 inhibits the growth of prostate cancer cells through sustained activation of Erk1/2, c-jun/c-fos-dependent upregulation of p21, and induction of G(2) cell-cycle arrest
-
Q.K. Chan, H.M. Lam, C.F. Ng, A.Y. Lee, E.S. Chan, and H.K. Ng Activation of GPR30 inhibits the growth of prostate cancer cells through sustained activation of Erk1/2, c-jun/c-fos-dependent upregulation of p21, and induction of G(2) cell-cycle arrest Cell Death Differ 17 2010 1511 1523
-
(2010)
Cell Death Differ
, vol.17
, pp. 1511-1523
-
-
Chan, Q.K.1
Lam, H.M.2
Ng, C.F.3
Lee, A.Y.4
Chan, E.S.5
Ng, H.K.6
-
101
-
-
62049084027
-
Estrogenic GPR30 signalling induces proliferation and migration of breast cancer cells through CTGF
-
D.P. Pandey, R. Lappano, L. Albanito, A. Madeo, M. Maggiolini, and D. Picard Estrogenic GPR30 signalling induces proliferation and migration of breast cancer cells through CTGF EMBO J 28 2009 523 532
-
(2009)
EMBO J
, vol.28
, pp. 523-532
-
-
Pandey, D.P.1
Lappano, R.2
Albanito, L.3
Madeo, A.4
Maggiolini, M.5
Picard, D.6
-
102
-
-
33344461590
-
The G protein-coupled receptor GPR30 mediates the proliferative effects induced by 17beta-estradiol and hydroxytamoxifen in endometrial cancer cells
-
A. Vivacqua, D. Bonofiglio, A.G. Recchia, A.M. Musti, D. Picard, and S. Ando The G protein-coupled receptor GPR30 mediates the proliferative effects induced by 17beta-estradiol and hydroxytamoxifen in endometrial cancer cells Mol Endocrinol 20 2006 631 646
-
(2006)
Mol Endocrinol
, vol.20
, pp. 631-646
-
-
Vivacqua, A.1
Bonofiglio, D.2
Recchia, A.G.3
Musti, A.M.4
Picard, D.5
Ando, S.6
-
103
-
-
0030066470
-
Nuclear signaling by endothelin-1 requires Src protein-tyrosine kinases
-
M.S. Simonson, Y. Wang, and W.H. Herman Nuclear signaling by endothelin-1 requires Src protein-tyrosine kinases J Biol Chem 271 1996 77 82
-
(1996)
J Biol Chem
, vol.271
, pp. 77-82
-
-
Simonson, M.S.1
Wang, Y.2
Herman, W.H.3
-
104
-
-
0029154733
-
Protein tyrosine kinase PYK2 involved in Ca(2 +)-induced regulation of ion channel and MAP kinase functions
-
S. Lev, H. Moreno, R. Martinez, P. Canoll, E. Peles, and J.M. Musacchio Protein tyrosine kinase PYK2 involved in Ca(2 +)-induced regulation of ion channel and MAP kinase functions Nature 376 1995 737 745
-
(1995)
Nature
, vol.376
, pp. 737-745
-
-
Lev, S.1
Moreno, H.2
Martinez, R.3
Canoll, P.4
Peles, E.5
Musacchio, J.M.6
-
105
-
-
0029907265
-
A role for Pyk2 and Src in linking G-protein-coupled receptors with MAP kinase activation
-
I. Dikic, G. Tokiwa, S. Lev, S.A. Courtneidge, and J. Schlessinger A role for Pyk2 and Src in linking G-protein-coupled receptors with MAP kinase activation Nature 383 1996 547 550
-
(1996)
Nature
, vol.383
, pp. 547-550
-
-
Dikic, I.1
Tokiwa, G.2
Lev, S.3
Courtneidge, S.A.4
Schlessinger, J.5
-
106
-
-
0035827528
-
Src and Pyk2 mediate G-protein-coupled receptor activation of epidermal growth factor receptor (EGFR) but are not required for coupling to the mitogen-Activated protein (MAP) kinase signaling cascade
-
J. Andreev, M.L. Galisteo, O. Kranenburg, S.K. Logan, E.S. Chiu, and M. Okigaki Src and Pyk2 mediate G-protein-coupled receptor activation of epidermal growth factor receptor (EGFR) but are not required for coupling to the mitogen-Activated protein (MAP) kinase signaling cascade J Biol Chem 276 2001 20130 20135
-
(2001)
J Biol Chem
, vol.276
, pp. 20130-20135
-
-
Andreev, J.1
Galisteo, M.L.2
Kranenburg, O.3
Logan, S.K.4
Chiu, E.S.5
Okigaki, M.6
-
107
-
-
0030837027
-
The m1 muscarinic acetylcholine receptor transactivates the EGF receptor to modulate ion channel activity
-
W. Tsai, A.D. Morielli, and E.G. Peralta The m1 muscarinic acetylcholine receptor transactivates the EGF receptor to modulate ion channel activity EMBO J 16 1997 4597 4605
-
(1997)
EMBO J
, vol.16
, pp. 4597-4605
-
-
Tsai, W.1
Morielli, A.D.2
Peralta, E.G.3
-
108
-
-
0032538622
-
Carbachol stimulates transactivation of epidermal growth factor receptor and mitogen-Activated protein kinase in T84 cells. Implications for carbachol-stimulated chloride secretion
-
S.J. Keely, J.M. Uribe, and K.E. Barrett Carbachol stimulates transactivation of epidermal growth factor receptor and mitogen-Activated protein kinase in T84 cells. Implications for carbachol-stimulated chloride secretion J Biol Chem 273 1998 27111 27117
-
(1998)
J Biol Chem
, vol.273
, pp. 27111-27117
-
-
Keely, S.J.1
Uribe, J.M.2
Barrett, K.E.3
-
109
-
-
0034697127
-
Distinct effects of N-Acetylcysteine and nitric oxide on angiotensin II-induced epidermal growth factor receptor phosphorylation and intracellular Ca(2 +) levels
-
D. Wang, X. Yu, R.A. Cohen, and P. Brecher Distinct effects of N-Acetylcysteine and nitric oxide on angiotensin II-induced epidermal growth factor receptor phosphorylation and intracellular Ca(2 +) levels J Biol Chem 275 2000 12223 12230
-
(2000)
J Biol Chem
, vol.275
, pp. 12223-12230
-
-
Wang, D.1
Yu, X.2
Cohen, R.A.3
Brecher, P.4
-
110
-
-
0034717056
-
Angiotensin II induces transactivation of two different populations of the platelet-derived growth factor beta receptor. Key role for the p66 adaptor protein Shc
-
S. Heeneman, J. Haendeler, Y. Saito, M. Ishida, and B.C. Berk Angiotensin II induces transactivation of two different populations of the platelet-derived growth factor beta receptor. Key role for the p66 adaptor protein Shc J Biol Chem 275 2000 15926 15932
-
(2000)
J Biol Chem
, vol.275
, pp. 15926-15932
-
-
Heeneman, S.1
Haendeler, J.2
Saito, Y.3
Ishida, M.4
Berk, B.C.5
-
111
-
-
0029074408
-
Convergence of angiotensin II and platelet-derived growth factor receptor signaling cascades in vascular smooth muscle cells
-
D.A. Linseman, C.W. Benjamin, and D.A. Jones Convergence of angiotensin II and platelet-derived growth factor receptor signaling cascades in vascular smooth muscle cells J Biol Chem 270 1995 12563 12568
-
(1995)
J Biol Chem
, vol.270
, pp. 12563-12568
-
-
Linseman, D.A.1
Benjamin, C.W.2
Jones, D.A.3
-
112
-
-
0034697092
-
Involvement of the platelet-derived growth factor receptor in angiotensin II-induced activation of extracellular regulated kinases 1 and 2 in human mesangial cells
-
U.F. Mondorf, H. Geiger, M. Herrero, S. Zeuzem, and A. Piiper Involvement of the platelet-derived growth factor receptor in angiotensin II-induced activation of extracellular regulated kinases 1 and 2 in human mesangial cells FEBS Lett 472 2000 129 132
-
(2000)
FEBS Lett
, vol.472
, pp. 129-132
-
-
Mondorf, U.F.1
Geiger, H.2
Herrero, M.3
Zeuzem, S.4
Piiper, A.5
-
113
-
-
0030866476
-
Stimulated activation of platelet-derived growth factor receptor in vivo in balloon-injured arteries: A link between angiotensin II and intimal thickening
-
J. Abe, J. Deguchi, T. Matsumoto, N. Takuwa, M. Noda, and M. Ohno Stimulated activation of platelet-derived growth factor receptor in vivo in balloon-injured arteries: a link between angiotensin II and intimal thickening Circulation 96 1997 1906 1913
-
(1997)
Circulation
, vol.96
, pp. 1906-1913
-
-
Abe, J.1
Deguchi, J.2
Matsumoto, T.3
Takuwa, N.4
Noda, M.5
Ohno, M.6
-
114
-
-
0034665584
-
Transactivation of the epidermal growth factor receptor in endothelin-1-induced mitogenic signaling in human ovarian carcinoma cells
-
F. Vacca, A. Bagnato, K.J. Catt, and R. Tecce Transactivation of the epidermal growth factor receptor in endothelin-1-induced mitogenic signaling in human ovarian carcinoma cells Cancer Res 60 2000 5310 5317
-
(2000)
Cancer Res
, vol.60
, pp. 5310-5317
-
-
Vacca, F.1
Bagnato, A.2
Catt, K.J.3
Tecce, R.4
-
115
-
-
77955024164
-
Nuclear alternate estrogen receptor GPR30 mediates 17beta-estradiol- induced gene expression and migration in breast cancer-Associated fibroblasts
-
A. Madeo, and M. Maggiolini Nuclear alternate estrogen receptor GPR30 mediates 17beta-estradiol-induced gene expression and migration in breast cancer-Associated fibroblasts Cancer Res 70 2010 6036 6046
-
(2010)
Cancer Res
, vol.70
, pp. 6036-6046
-
-
Madeo, A.1
Maggiolini, M.2
-
116
-
-
84855195867
-
Cross-talk and modulation of signaling between somatostatin and growth factor receptors
-
U. Kumar Cross-talk and modulation of signaling between somatostatin and growth factor receptors Endocrine 40 2011 168 180
-
(2011)
Endocrine
, vol.40
, pp. 168-180
-
-
Kumar, U.1
-
117
-
-
58249143438
-
Somatostatin receptors 1 and 5 heterodimerize with epidermal growth factor receptor: Agonist-dependent modulation of the downstream MAPK signalling pathway in breast cancer cells
-
H.L. Watt, G.D. Kharmate, and U. Kumar Somatostatin receptors 1 and 5 heterodimerize with epidermal growth factor receptor: agonist-dependent modulation of the downstream MAPK signalling pathway in breast cancer cells Cell Signal 21 2009 428 439
-
(2009)
Cell Signal
, vol.21
, pp. 428-439
-
-
Watt, H.L.1
Kharmate, G.D.2
Kumar, U.3
-
118
-
-
79955646925
-
Role of somatostatin receptor 1 and 5 on epidermal growth factor receptor mediated signaling
-
G. Kharmate, P.S. Rajput, H.L. Watt, R.K. Somvanshi, N. Chaudhari, and X. Qiu Role of somatostatin receptor 1 and 5 on epidermal growth factor receptor mediated signaling Biochim Biophys Acta 1813 2011 1172 1189
-
(2011)
Biochim Biophys Acta
, vol.1813
, pp. 1172-1189
-
-
Kharmate, G.1
Rajput, P.S.2
Watt, H.L.3
Somvanshi, R.K.4
Chaudhari, N.5
Qiu, X.6
-
119
-
-
79951938154
-
Dissociation of epidermal growth factor receptor and ErbB2 heterodimers in the presence of somatostatin receptor 5 modulate signaling pathways
-
G. Kharmate, P.S. Rajput, H.L. Watt, R.K. Somvanshi, N. Chaudhari, and X. Qiu Dissociation of epidermal growth factor receptor and ErbB2 heterodimers in the presence of somatostatin receptor 5 modulate signaling pathways Endocrinology 152 2011 931 945
-
(2011)
Endocrinology
, vol.152
, pp. 931-945
-
-
Kharmate, G.1
Rajput, P.S.2
Watt, H.L.3
Somvanshi, R.K.4
Chaudhari, N.5
Qiu, X.6
-
120
-
-
35148885729
-
A functional genetic approach identifies the PI3K pathway as a major determinant of trastuzumab resistance in breast cancer
-
K. Berns, H.M. Horlings, B.T. Hennessy, M. Madiredjo, E.M. Hijmans, and K. Beelen A functional genetic approach identifies the PI3K pathway as a major determinant of trastuzumab resistance in breast cancer Cancer Cell 12 2007 395 402
-
(2007)
Cancer Cell
, vol.12
, pp. 395-402
-
-
Berns, K.1
Horlings, H.M.2
Hennessy, B.T.3
Madiredjo, M.4
Hijmans, E.M.5
Beelen, K.6
-
121
-
-
36448956774
-
GPCR-jacking: From a new route in RTK signalling to a new concept in GPCR activation
-
N. Delcourt, J. Bockaert, and P. Marin GPCR-jacking: from a new route in RTK signalling to a new concept in GPCR activation Trends Pharmacol Sci 28 2007 602 607
-
(2007)
Trends Pharmacol Sci
, vol.28
, pp. 602-607
-
-
Delcourt, N.1
Bockaert, J.2
Marin, P.3
-
122
-
-
0035090647
-
A role for chemokine receptor transactivation in growth factor signaling
-
E. Mira, R.A. Lacalle, M.A. Gonzalez, C. Gomez-Mouton, J.L. Abad, and A. Bernad A role for chemokine receptor transactivation in growth factor signaling EMBO Rep 2 2001 151 156
-
(2001)
EMBO Rep
, vol.2
, pp. 151-156
-
-
Mira, E.1
Lacalle, R.A.2
Gonzalez, M.A.3
Gomez-Mouton, C.4
Abad, J.L.5
Bernad, A.6
-
123
-
-
0035793866
-
Role of the sphingosine-1-phosphate receptor EDG-1 in PDGF-induced cell motility
-
J.P. Hobson, H.M. Rosenfeldt, L.S. Barak, A. Olivera, S. Poulton, and M.G. Caron Role of the sphingosine-1-phosphate receptor EDG-1 in PDGF-induced cell motility Science 291 2001 1800 1803
-
(2001)
Science
, vol.291
, pp. 1800-1803
-
-
Hobson, J.P.1
Rosenfeldt, H.M.2
Barak, L.S.3
Olivera, A.4
Poulton, S.5
Caron, M.G.6
-
124
-
-
28844458917
-
Transactivation of CXCR4 by the insulin-like growth factor-1 receptor (IGF-1R) in human MDA-MB-231 breast cancer epithelial cells
-
C. Akekawatchai, J.D. Holland, M. Kochetkova, J.C. Wallace, and S.R. McColl Transactivation of CXCR4 by the insulin-like growth factor-1 receptor (IGF-1R) in human MDA-MB-231 breast cancer epithelial cells J Biol Chem 280 2005 39701 39708
-
(2005)
J Biol Chem
, vol.280
, pp. 39701-39708
-
-
Akekawatchai, C.1
Holland, J.D.2
Kochetkova, M.3
Wallace, J.C.4
McColl, S.R.5
-
125
-
-
0028982925
-
G beta gamma subunits mediate mitogen-Activated protein kinase activation by the tyrosine kinase insulin-like growth factor 1 receptor
-
L.M. Luttrell, T. van Biesen, B.E. Hawes, W.J. Koch, K. Touhara, and R.J. Lefkowitz G beta gamma subunits mediate mitogen-Activated protein kinase activation by the tyrosine kinase insulin-like growth factor 1 receptor J Biol Chem 270 1995 16495 16498
-
(1995)
J Biol Chem
, vol.270
, pp. 16495-16498
-
-
Luttrell, L.M.1
Van Biesen, T.2
Hawes, B.E.3
Koch, W.J.4
Touhara, K.5
Lefkowitz, R.J.6
-
126
-
-
0035958899
-
Tethering of the platelet-derived growth factor beta receptor to G-protein-coupled receptors. A novel platform for integrative signaling by these receptor classes in mammalian cells
-
F. Alderton, S. Rakhit, K.C. Kong, T. Palmer, B. Sambi, and S. Pyne Tethering of the platelet-derived growth factor beta receptor to G-protein-coupled receptors. A novel platform for integrative signaling by these receptor classes in mammalian cells J Biol Chem 276 2001 28578 28585
-
(2001)
J Biol Chem
, vol.276
, pp. 28578-28585
-
-
Alderton, F.1
Rakhit, S.2
Kong, K.C.3
Palmer, T.4
Sambi, B.5
Pyne, S.6
-
127
-
-
84857482783
-
Constitutive formation of an RXFP1-signalosome: A novel paradigm in GPCR function and regulation
-
M.L. Halls Constitutive formation of an RXFP1-signalosome: a novel paradigm in GPCR function and regulation Br J Pharmacol 165 2012 1644 1658
-
(2012)
Br J Pharmacol
, vol.165
, pp. 1644-1658
-
-
Halls, M.L.1
-
128
-
-
80052606605
-
Molecular basis of lysophosphatidic acid-induced NF-kappaB activation
-
W. Sun, and J. Yang Molecular basis of lysophosphatidic acid-induced NF-kappaB activation Cell Signal 22 2010 1799 1803
-
(2010)
Cell Signal
, vol.22
, pp. 1799-1803
-
-
Sun, W.1
Yang, J.2
-
129
-
-
49649105002
-
Blood pressure is regulated by an alpha1D-Adrenergic receptor/dystrophin signalosome
-
J.S. Lyssand, M.C. DeFino, X.B. Tang, A.L. Hertz, D.B. Feller, and J.L. Wacker Blood pressure is regulated by an alpha1D-Adrenergic receptor/dystrophin signalosome J Biol Chem 283 2008 18792 18800
-
(2008)
J Biol Chem
, vol.283
, pp. 18792-18800
-
-
Lyssand, J.S.1
Defino, M.C.2
Tang, X.B.3
Hertz, A.L.4
Feller, D.B.5
Wacker, J.L.6
-
130
-
-
77955853530
-
Sub-picomolar relaxin signalling by a pre-Assembled RXFP1, AKAP79, AC2, beta-Arrestin 2, PDE4D3 complex
-
M.L. Halls, and D.M. Cooper Sub-picomolar relaxin signalling by a pre-Assembled RXFP1, AKAP79, AC2, beta-Arrestin 2, PDE4D3 complex EMBO J 29 2010 2772 2787
-
(2010)
EMBO J
, vol.29
, pp. 2772-2787
-
-
Halls, M.L.1
Cooper, D.M.2
-
131
-
-
38749100594
-
Relaxin-like ligand-receptor systems are autocrine/paracrine effectors in tumor cells and modulate cancer progression and tissue invasiveness
-
T. Klonisch, J. Bialek, Y. Radestock, C. Hoang-Vu, and S. Hombach-Klonisch Relaxin-like ligand-receptor systems are autocrine/paracrine effectors in tumor cells and modulate cancer progression and tissue invasiveness Adv Exp Med Biol 612 2007 104 118
-
(2007)
Adv Exp Med Biol
, vol.612
, pp. 104-118
-
-
Klonisch, T.1
Bialek, J.2
Radestock, Y.3
Hoang-Vu, C.4
Hombach-Klonisch, S.5
-
132
-
-
0034114769
-
Blockade of receptors for growth factors: An anticancer therapy - The fourth annual Joseph H Burchenal American Association of Cancer Research Clinical Research Award Lecture
-
J. Mendelsohn Blockade of receptors for growth factors: an anticancer therapy - the fourth annual Joseph H Burchenal American Association of Cancer Research Clinical Research Award Lecture Clin Cancer Res 6 2000 747 753
-
(2000)
Clin Cancer Res
, vol.6
, pp. 747-753
-
-
Mendelsohn, J.1
-
133
-
-
33745031603
-
Peptide hormones and lung cancer
-
T.W. Moody Peptide hormones and lung cancer Panminerva Med 48 2006 19 26
-
(2006)
Panminerva Med
, vol.48
, pp. 19-26
-
-
Moody, T.W.1
-
134
-
-
0036551292
-
Neuropeptides as growth factors for normal and cancerous cells
-
E. Rozengurt Neuropeptides as growth factors for normal and cancerous cells Trends Endocrinol Metab 13 2002 128 134
-
(2002)
Trends Endocrinol Metab
, vol.13
, pp. 128-134
-
-
Rozengurt, E.1
-
136
-
-
0021807624
-
Bombesin-like peptides can function as autocrine growth factors in human small-cell lung cancer
-
F. Cuttitta, D.N. Carney, J. Mulshine, T.W. Moody, J. Fedorko, and A. Fischler Bombesin-like peptides can function as autocrine growth factors in human small-cell lung cancer Nature 316 1985 823 826
-
(1985)
Nature
, vol.316
, pp. 823-826
-
-
Cuttitta, F.1
Carney, D.N.2
Mulshine, J.3
Moody, T.W.4
Fedorko, J.5
Fischler, A.6
-
137
-
-
0022409248
-
A peptide that inhibits the mitogenic stimulation of Swiss 3T3 cells by bombesin or vasopressin
-
A.N. Corps, L.H. Rees, and K.D. Brown A peptide that inhibits the mitogenic stimulation of Swiss 3T3 cells by bombesin or vasopressin Biochem J 231 1985 781 784
-
(1985)
Biochem J
, vol.231
, pp. 781-784
-
-
Corps, A.N.1
Rees, L.H.2
Brown, K.D.3
-
138
-
-
0021238374
-
A synthetic peptide that is a bombesin receptor antagonist
-
R.T. Jensen, S.W. Jones, K. Folkers, and J.D. Gardner A synthetic peptide that is a bombesin receptor antagonist Nature 309 1984 61 63
-
(1984)
Nature
, vol.309
, pp. 61-63
-
-
Jensen, R.T.1
Jones, S.W.2
Folkers, K.3
Gardner, J.D.4
-
139
-
-
0021992306
-
Block of the hyoscine-resistant opiate withdrawal contracture of ileum by a new substance P antagonist [D-Arg1, D-Phe5, D- Trp7,9, Leu 11]substance P
-
K. Tsou, S.X. Wu, Y.A. Lu, and E.L. Way Block of the hyoscine-resistant opiate withdrawal contracture of ileum by a new substance P antagonist [D-Arg1, D-Phe5, D- Trp7,9, Leu 11]substance P Eur J Pharmacol 110 1985 155 156
-
(1985)
Eur J Pharmacol
, vol.110
, pp. 155-156
-
-
Tsou, K.1
Wu, S.X.2
Lu, Y.A.3
Way, E.L.4
-
140
-
-
0024163078
-
[D-Arg1, D-Phe5, D-Trp7,9, Leu11]substance P, a potent bombesin antagonist in murine Swiss 3T3 cells, inhibits the growth of human small cell lung cancer cells in vitro
-
P.J. Woll, and E. Rozengurt [D-Arg1, D-Phe5, D-Trp7,9, Leu11]substance P, a potent bombesin antagonist in murine Swiss 3T3 cells, inhibits the growth of human small cell lung cancer cells in vitro Proc Natl Acad Sci USA 85 1988 1859 1863
-
(1988)
Proc Natl Acad Sci USA
, vol.85
, pp. 1859-1863
-
-
Woll, P.J.1
Rozengurt, E.2
-
141
-
-
0024154851
-
Two classes of antagonist interact with receptors for the mitogenic neuropeptides bombesin, bradykinin, and vasopressin
-
P.J. Woll, and E. Rozengurt Two classes of antagonist interact with receptors for the mitogenic neuropeptides bombesin, bradykinin, and vasopressin Growth Factors 1 1988 75 83
-
(1988)
Growth Factors
, vol.1
, pp. 75-83
-
-
Woll, P.J.1
Rozengurt, E.2
-
142
-
-
0025937032
-
The inhibitory effect of [D-Arg1, D-Phe, D-Try7,9, Leu11]substance P on endothelin-1 binding sites in rat cardiac membranes
-
X.H. Gu, D.J. Casley, and W.G. Nayler The inhibitory effect of [D-Arg1, D-Phe, D-Try7,9, Leu11]substance P on endothelin-1 binding sites in rat cardiac membranes Biochem Biophys Res Commun 179 1991 130 133
-
(1991)
Biochem Biophys Res Commun
, vol.179
, pp. 130-133
-
-
Gu, X.H.1
Casley, D.J.2
Nayler, W.G.3
-
143
-
-
0032579002
-
[D-Arg1, D-Phe5, D-Trp7,9, Leu11]substance P acts as a biased agonist toward neuropeptide and chemokine receptors
-
M.B. Jarpe, C. Knall, F.M. Mitchell, A.M. Buhl, E. Duzic, and G.L. Johnson [D-Arg1, D-Phe5, D-Trp7,9, Leu11]substance P acts as a biased agonist toward neuropeptide and chemokine receptors J Biol Chem 273 1998 3097 3104
-
(1998)
J Biol Chem
, vol.273
, pp. 3097-3104
-
-
Jarpe, M.B.1
Knall, C.2
Mitchell, F.M.3
Buhl, A.M.4
Duzic, E.5
Johnson, G.L.6
-
144
-
-
0028174947
-
[D-Arg1, D-Phe5, D-Trp7,9, Leu11]substance P induces apoptosis in lung cancer cell lines in vitro
-
J.G. Reeve, and N.M. Bleehen [D-Arg1, D-Phe5, D-Trp7,9, Leu11]substance P induces apoptosis in lung cancer cell lines in vitro Biochem Biophys Res Commun 199 1994 1313 1319
-
(1994)
Biochem Biophys Res Commun
, vol.199
, pp. 1313-1319
-
-
Reeve, J.G.1
Bleehen, N.M.2
-
145
-
-
0030614842
-
[D-Arg1, D-Trp5,7,9, Leu11]substance P: A novel potent inhibitor of signal transduction and growth in vitro and in vivo in small cell lung cancer cells
-
M.J. Seckl, T. Higgins, F. Widmer, and E. Rozengurt [D-Arg1, D-Trp5,7,9, Leu11]substance P: a novel potent inhibitor of signal transduction and growth in vitro and in vivo in small cell lung cancer cells Cancer Res 57 1997 51 54
-
(1997)
Cancer Res
, vol.57
, pp. 51-54
-
-
Seckl, M.J.1
Higgins, T.2
Widmer, F.3
Rozengurt, E.4
-
146
-
-
0026681259
-
Growth of small cell lung cancer cells: Stimulation by multiple neuropeptides and inhibition by broad spectrum antagonists in vitro and in vivo
-
T. Sethi, S. Langdon, J. Smyth, and E. Rozengurt Growth of small cell lung cancer cells: stimulation by multiple neuropeptides and inhibition by broad spectrum antagonists in vitro and in vivo Cancer Res 52 1992 2737s 2742s
-
(1992)
Cancer Res
, vol.52
-
-
Sethi, T.1
Langdon, S.2
Smyth, J.3
Rozengurt, E.4
-
147
-
-
0025323953
-
A neuropeptide antagonist that inhibits the growth of small cell lung cancer in vitro
-
P.J. Woll, and E. Rozengurt A neuropeptide antagonist that inhibits the growth of small cell lung cancer in vitro Cancer Res 50 1990 3968 3973
-
(1990)
Cancer Res
, vol.50
, pp. 3968-3973
-
-
Woll, P.J.1
Rozengurt, E.2
-
148
-
-
0026801445
-
Broad spectrum neuropeptide antagonists inhibit the growth of small cell lung cancer in vivo
-
S. Langdon, T. Sethi, A. Ritchie, M. Muir, J. Smyth, and E. Rozengurt Broad spectrum neuropeptide antagonists inhibit the growth of small cell lung cancer in vivo Cancer Res 52 1992 4554 4557
-
(1992)
Cancer Res
, vol.52
, pp. 4554-4557
-
-
Langdon, S.1
Sethi, T.2
Ritchie, A.3
Muir, M.4
Smyth, J.5
Rozengurt, E.6
-
149
-
-
0033146386
-
[Arg6, D-Trp7,9, NmePhe8]-substance P (6-11) activates JNK and induces apoptosis in small cell lung cancer cells via an oxidant-dependent mechanism
-
A.C. MacKinnon, R.A. Armstrong, C.M. Waters, J. Cummings, J.F. Smyth, and C. Haslett [Arg6, D-Trp7,9, NmePhe8]-substance P (6-11) activates JNK and induces apoptosis in small cell lung cancer cells via an oxidant-dependent mechanism Br J Cancer 80 1999 1026 1034
-
(1999)
Br J Cancer
, vol.80
, pp. 1026-1034
-
-
MacKinnon, A.C.1
Armstrong, R.A.2
Waters, C.M.3
Cummings, J.4
Smyth, J.F.5
Haslett, C.6
-
150
-
-
0141649387
-
Bradykinin antagonists as anti-cancer agents
-
J.M. Stewart Bradykinin antagonists as anti-cancer agents Curr Pharm Des 9 2003 2036 2042
-
(2003)
Curr Pharm des
, vol.9
, pp. 2036-2042
-
-
Stewart, J.M.1
-
151
-
-
16844365620
-
Broad-spectrum G protein-coupled receptor antagonist, [D-Arg1, D-Trp5,7,9, Leu11]SP: A dual inhibitor of growth and angiogenesis in pancreatic cancer
-
S. Guha, G. Eibl, K. Kisfalvi, R.S. Fan, M. Burdick, and H. Reber Broad-spectrum G protein-coupled receptor antagonist, [D-Arg1, D-Trp5,7,9, Leu11]SP: a dual inhibitor of growth and angiogenesis in pancreatic cancer Cancer Res 65 2005 2738 2745
-
(2005)
Cancer Res
, vol.65
, pp. 2738-2745
-
-
Guha, S.1
Eibl, G.2
Kisfalvi, K.3
Fan, R.S.4
Burdick, M.5
Reber, H.6
-
152
-
-
18344388451
-
Bradykinin antagonist dimer, CU201, inhibits the growth of human lung cancer cell lines by a "biased agonist" mechanism
-
D. Chan, L. Gera, J. Stewart, B. Helfrich, M. Verella-Garcia, and G. Johnson Bradykinin antagonist dimer, CU201, inhibits the growth of human lung cancer cell lines by a "biased agonist" mechanism Proc Natl Acad Sci USA 99 2002 4608 4613
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 4608-4613
-
-
Chan, D.1
Gera, L.2
Stewart, J.3
Helfrich, B.4
Verella-Garcia, M.5
Johnson, G.6
-
153
-
-
0036097190
-
Bradykinin antagonist dimer, CU201, inhibits the growth of human lung cancer cell lines in vitro and in vivo and produces synergistic growth inhibition in combination with other antitumor agents
-
D.C. Chan, L. Gera, J.M. Stewart, B. Helfrich, T.L. Zhao, and W.Y. Feng Bradykinin antagonist dimer, CU201, inhibits the growth of human lung cancer cell lines in vitro and in vivo and produces synergistic growth inhibition in combination with other antitumor agents Clin Cancer Res 8 2002 1280 1287
-
(2002)
Clin Cancer Res
, vol.8
, pp. 1280-1287
-
-
Chan, D.C.1
Gera, L.2
Stewart, J.M.3
Helfrich, B.4
Zhao, T.L.5
Feng, W.Y.6
-
154
-
-
0036243338
-
Bradykinin-related compounds as new drugs for cancer and inflammation
-
J.M. Stewart, L. Gera, D.C. Chan, P.A. Bunn Jr., E.J. York, and V. Simkeviciene Bradykinin-related compounds as new drugs for cancer and inflammation Can J Physiol Pharmacol 80 2002 275 280
-
(2002)
Can J Physiol Pharmacol
, vol.80
, pp. 275-280
-
-
Stewart, J.M.1
Gera, L.2
Chan, D.C.3
Bunn, Jr.P.A.4
York, E.J.5
Simkeviciene, V.6
-
155
-
-
82155172862
-
Somatostatin-dopamine chimeras: A novel approach to treatment of neuroendocrine tumors
-
M.D. Culler Somatostatin-dopamine chimeras: a novel approach to treatment of neuroendocrine tumors Horm Metab Res 43 2011 854 857
-
(2011)
Horm Metab Res
, vol.43
, pp. 854-857
-
-
Culler, M.D.1
-
156
-
-
0037323565
-
The pathophysiological consequences of somatostatin receptor internalization and resistance
-
L.J. Hofland, and S.W. Lamberts The pathophysiological consequences of somatostatin receptor internalization and resistance Endocr Rev 24 2003 28 47
-
(2003)
Endocr Rev
, vol.24
, pp. 28-47
-
-
Hofland, L.J.1
Lamberts, S.W.2
-
157
-
-
0036111856
-
SOM230: A novel somatostatin peptidomimetic with broad somatotropin release inhibiting factor (SRIF) receptor binding and a unique antisecretory profile
-
C. Bruns, I. Lewis, U. Briner, G. Meno-Tetang, and G. Weckbecker SOM230: a novel somatostatin peptidomimetic with broad somatotropin release inhibiting factor (SRIF) receptor binding and a unique antisecretory profile Eur J Endocrinol 146 2002 707 716
-
(2002)
Eur J Endocrinol
, vol.146
, pp. 707-716
-
-
Bruns, C.1
Lewis, I.2
Briner, U.3
Meno-Tetang, G.4
Weckbecker, G.5
-
158
-
-
17744399907
-
Bim-23244, a somatostatin receptor subtype 2- and 5-selective analog with enhanced efficacy in suppressing growth hormone (GH) from octreotide-resistant human GH-secreting adenomas
-
A. Saveanu, G. Gunz, H. Dufour, P. Caron, F. Fina, and L. Ouafik Bim-23244, a somatostatin receptor subtype 2- and 5-selective analog with enhanced efficacy in suppressing growth hormone (GH) from octreotide-resistant human GH-secreting adenomas J Clin Endocrinol Metab 86 2001 140 145
-
(2001)
J Clin Endocrinol Metab
, vol.86
, pp. 140-145
-
-
Saveanu, A.1
Gunz, G.2
Dufour, H.3
Caron, P.4
Fina, F.5
Ouafik, L.6
-
159
-
-
79953276336
-
Somatostatin analogs for the treatment of neuroendocrine tumors
-
M.D. Culler, K. Oberg, R. Arnold, E.P. Krenning, I. Sevilla, and J.A. Diaz Somatostatin analogs for the treatment of neuroendocrine tumors Cancer Metastasis Rev 30 Suppl. 1 2011 9 17
-
(2011)
Cancer Metastasis Rev
, vol.30
, Issue.SUPPL. 1
, pp. 9-17
-
-
Culler, M.D.1
Oberg, K.2
Arnold, R.3
Krenning, E.P.4
Sevilla, I.5
Diaz, J.A.6
-
160
-
-
0021994564
-
Bromocriptine as primary therapy for prolactin-secreting macroadenomas: Results of a prospective multicenter study
-
M.E. Molitch, R.L. Elton, R.E. Blackwell, B. Caldwell, R.J. Chang, and R. Jaffe Bromocriptine as primary therapy for prolactin-secreting macroadenomas: results of a prospective multicenter study J Clin Endocrinol Metab 60 1985 698 705
-
(1985)
J Clin Endocrinol Metab
, vol.60
, pp. 698-705
-
-
Molitch, M.E.1
Elton, R.L.2
Blackwell, R.E.3
Caldwell, B.4
Chang, R.J.5
Jaffe, R.6
-
161
-
-
0031017930
-
Prolactinomas resistant to standard dopamine agonists respond to chronic cabergoline treatment
-
A. Colao, A. Di Sarno, F. Sarnacchiaro, D. Ferone, G. Di Renzo, and B. Merola Prolactinomas resistant to standard dopamine agonists respond to chronic cabergoline treatment J Clin Endocrinol Metab 82 1997 876 883
-
(1997)
J Clin Endocrinol Metab
, vol.82
, pp. 876-883
-
-
Colao, A.1
Di Sarno, A.2
Sarnacchiaro, F.3
Ferone, D.4
Di Renzo, G.5
Merola, B.6
-
162
-
-
2442610476
-
Dopamine receptor expression and function in corticotroph pituitary tumors
-
R. Pivonello, D. Ferone, W.W. de Herder, J.M. Kros, M.L. De Caro, and M. Arvigo Dopamine receptor expression and function in corticotroph pituitary tumors J Clin Endocrinol Metab 89 2004 2452 2462
-
(2004)
J Clin Endocrinol Metab
, vol.89
, pp. 2452-2462
-
-
Pivonello, R.1
Ferone, D.2
De Herder, W.W.3
Kros, J.M.4
De Caro, M.L.5
Arvigo, M.6
-
163
-
-
0028111227
-
A comparison of octreotide, bromocriptine, or a combination of both drugs in acromegaly
-
A.K. Flogstad, J. Halse, P. Grass, E. Abisch, O. Djoseland, and K. Kutz A comparison of octreotide, bromocriptine, or a combination of both drugs in acromegaly J Clin Endocrinol Metab 79 1994 461 465
-
(1994)
J Clin Endocrinol Metab
, vol.79
, pp. 461-465
-
-
Flogstad, A.K.1
Halse, J.2
Grass, P.3
Abisch, E.4
Djoseland, O.5
Kutz, K.6
-
164
-
-
0031305655
-
Acute effects of octreotide, cabergoline and a combination of both drugs on GH secretion in acromegalic patients
-
G. Minniti, M.L. Jaffrain-Rea, R. Baldelli, E. Ferretti, B. Caracciolo, and A. Bultrini Acute effects of octreotide, cabergoline and a combination of both drugs on GH secretion in acromegalic patients Clin Ter 148 1997 601 607
-
(1997)
Clin ter
, vol.148
, pp. 601-607
-
-
Minniti, G.1
Jaffrain-Rea, M.L.2
Baldelli, R.3
Ferretti, E.4
Caracciolo, B.5
Bultrini, A.6
-
165
-
-
0034616021
-
Receptors for dopamine and somatostatin: Formation of hetero-oligomers with enhanced functional activity
-
M. Rocheville, D.C. Lange, U. Kumar, S.C. Patel, R.C. Patel, and Y.C. Patel Receptors for dopamine and somatostatin: formation of hetero-oligomers with enhanced functional activity Science 288 2000 154 157
-
(2000)
Science
, vol.288
, pp. 154-157
-
-
Rocheville, M.1
Lange, D.C.2
Kumar, U.3
Patel, S.C.4
Patel, R.C.5
Patel, Y.C.6
-
166
-
-
34548450155
-
Heterooligomerization of human dopamine receptor 2 and somatostatin receptor 2 co-immunoprecipitation and fluorescence resonance energy transfer analysis
-
A. Baragli, H. Alturaihi, H.L. Watt, A. Abdallah, and U. Kumar Heterooligomerization of human dopamine receptor 2 and somatostatin receptor 2 co-immunoprecipitation and fluorescence resonance energy transfer analysis Cell Signal 19 2007 2304 2316
-
(2007)
Cell Signal
, vol.19
, pp. 2304-2316
-
-
Baragli, A.1
Alturaihi, H.2
Watt, H.L.3
Abdallah, A.4
Kumar, U.5
-
167
-
-
67349112176
-
Somatostatin and dopamine receptors as targets for medical treatment of Cushing's syndrome
-
C. de Bruin, R.A. Feelders, S.W. Lamberts, and L.J. Hofland Somatostatin and dopamine receptors as targets for medical treatment of Cushing's syndrome Rev Endocr Metab Disord 10 2009 91 102
-
(2009)
Rev Endocr Metab Disord
, vol.10
, pp. 91-102
-
-
De Bruin, C.1
Feelders, R.A.2
Lamberts, S.W.3
Hofland, L.J.4
-
168
-
-
67349160224
-
Somatostatin-dopamine ligands in the treatment of pituitary adenomas
-
A. Saveanu, and P. Jaquet Somatostatin-dopamine ligands in the treatment of pituitary adenomas Rev Endocr Metab Disord 10 2009 83 90
-
(2009)
Rev Endocr Metab Disord
, vol.10
, pp. 83-90
-
-
Saveanu, A.1
Jaquet, P.2
-
169
-
-
33644664300
-
Somatostatin and dopamine receptor expression in lung carcinoma cells and effects of chimeric somatostatin-dopamine molecules on cell proliferation
-
D. Ferone, M. Arvigo, C. Semino, P. Jaquet, A. Saveanu, and J.E. Taylor Somatostatin and dopamine receptor expression in lung carcinoma cells and effects of chimeric somatostatin-dopamine molecules on cell proliferation Am J Physiol Endocrinol Metab 289 2005 E1044 E1050
-
(2005)
Am J Physiol Endocrinol Metab
, vol.289
-
-
Ferone, D.1
Arvigo, M.2
Semino, C.3
Jaquet, P.4
Saveanu, A.5
Taylor, J.E.6
-
170
-
-
0344874253
-
Suppression of rat and human growth hormone and prolactin secretion by a novel somatostatin/dopaminergic chimeric ligand
-
S.G. Ren, S. Kim, J. Taylor, J. Dong, J.P. Moreau, and M.D. Culler Suppression of rat and human growth hormone and prolactin secretion by a novel somatostatin/dopaminergic chimeric ligand J Clin Endocrinol Metab 88 2003 5414 5421
-
(2003)
J Clin Endocrinol Metab
, vol.88
, pp. 5414-5421
-
-
Ren, S.G.1
Kim, S.2
Taylor, J.3
Dong, J.4
Moreau, J.P.5
Culler, M.D.6
-
171
-
-
0036929913
-
Demonstration of enhanced potency of a chimeric somatostatin-dopamine molecule, BIM-23A387, in suppressing growth hormone and prolactin secretion from human pituitary somatotroph adenoma cells
-
A. Saveanu, E. Lavaque, G. Gunz, A. Barlier, S. Kim, and J.E. Taylor Demonstration of enhanced potency of a chimeric somatostatin-dopamine molecule, BIM-23A387, in suppressing growth hormone and prolactin secretion from human pituitary somatotroph adenoma cells J Clin Endocrinol Metab 87 2002 5545 5552
-
(2002)
J Clin Endocrinol Metab
, vol.87
, pp. 5545-5552
-
-
Saveanu, A.1
Lavaque, E.2
Gunz, G.3
Barlier, A.4
Kim, S.5
Taylor, J.E.6
-
172
-
-
33744988373
-
BIM-23A760, a chimeric molecule directed towards somatostatin and dopamine receptors, vs universal somatostatin receptors ligands in GH-secreting pituitary adenomas partial responders to octreotide
-
P. Jaquet, G. Gunz, A. Saveanu, A. Barlier, H. Dufour, and J. Taylor BIM-23A760, a chimeric molecule directed towards somatostatin and dopamine receptors, vs universal somatostatin receptors ligands in GH-secreting pituitary adenomas partial responders to octreotide J Endocrinol Invest 28 2005 21 27
-
(2005)
J Endocrinol Invest
, vol.28
, pp. 21-27
-
-
Jaquet, P.1
Gunz, G.2
Saveanu, A.3
Barlier, A.4
Dufour, H.5
Taylor, J.6
-
173
-
-
33845923854
-
BRET analysis of GPCR oligomerization: Newer does not mean better
-
author reply 4
-
M. Bouvier, N. Heveker, R. Jockers, S. Marullo, and G. Milligan BRET analysis of GPCR oligomerization: newer does not mean better Nat Methods 4 2007 3 4 author reply 4
-
(2007)
Nat Methods
, vol.4
, pp. 3-4
-
-
Bouvier, M.1
Heveker, N.2
Jockers, R.3
Marullo, S.4
Milligan, G.5
-
174
-
-
58149299308
-
Ligand-independent higher-order multimerization of CXCR4, a G-protein-coupled chemokine receptor involved in targeted metastasis
-
M. Hamatake, T. Aoki, Y. Futahashi, E. Urano, N. Yamamoto, and J. Komano Ligand-independent higher-order multimerization of CXCR4, a G-protein-coupled chemokine receptor involved in targeted metastasis Cancer Sci 100 2009 95 102
-
(2009)
Cancer Sci
, vol.100
, pp. 95-102
-
-
Hamatake, M.1
Aoki, T.2
Futahashi, Y.3
Urano, E.4
Yamamoto, N.5
Komano, J.6
-
175
-
-
34547636173
-
Experimental challenge to a 'rigorous' BRET analysis of GPCR oligomerization
-
author reply 601
-
A. Salahpour, and B. Masri Experimental challenge to a 'rigorous' BRET analysis of GPCR oligomerization Nat Methods 4 2007 599 600 author reply 601
-
(2007)
Nat Methods
, vol.4
, pp. 599-600
-
-
Salahpour, A.1
Masri, B.2
-
176
-
-
79960145997
-
Receptor oligomerization: A pivotal mechanism for regulating chemokine function
-
L.M. Munoz, P. Lucas, B.L. Holgado, R. Barroso, B. Vega, and J.M. Rodriguez-Frade Receptor oligomerization: a pivotal mechanism for regulating chemokine function Pharmacol Ther 131 2011 351 358
-
(2011)
Pharmacol Ther
, vol.131
, pp. 351-358
-
-
Munoz, L.M.1
Lucas, P.2
Holgado, B.L.3
Barroso, R.4
Vega, B.5
Rodriguez-Frade, J.M.6
-
177
-
-
80053632361
-
Mechanisms regulating chemokine receptor activity
-
L.D. Bennett, J.M. Fox, and N. Signoret Mechanisms regulating chemokine receptor activity Immunology 134 2011 246 256
-
(2011)
Immunology
, vol.134
, pp. 246-256
-
-
Bennett, L.D.1
Fox, J.M.2
Signoret, N.3
-
178
-
-
0037474238
-
Ligand-independent dimerization of CXCR4, a principal HIV-1 coreceptor
-
G.J. Babcock, M. Farzan, and J. Sodroski Ligand-independent dimerization of CXCR4, a principal HIV-1 coreceptor J Biol Chem 278 2003 3378 3385
-
(2003)
J Biol Chem
, vol.278
, pp. 3378-3385
-
-
Babcock, G.J.1
Farzan, M.2
Sodroski, J.3
-
179
-
-
33750447940
-
Dimerization of CXCR4 in living malignant cells: Control of cell migration by a synthetic peptide that reduces homologous CXCR4 interactions
-
J. Wang, L. He, C.A. Combs, G. Roderiquez, and M.A. Norcross Dimerization of CXCR4 in living malignant cells: control of cell migration by a synthetic peptide that reduces homologous CXCR4 interactions Mol Cancer Ther 5 2006 2474 2483
-
(2006)
Mol Cancer Ther
, vol.5
, pp. 2474-2483
-
-
Wang, J.1
He, L.2
Combs, C.A.3
Roderiquez, G.4
Norcross, M.A.5
-
180
-
-
0035282432
-
Involvement of chemokine receptors in breast cancer metastasis
-
A. Muller, B. Homey, H. Soto, N. Ge, D. Catron, and M.E. Buchanan Involvement of chemokine receptors in breast cancer metastasis Nature 410 2001 50 56
-
(2001)
Nature
, vol.410
, pp. 50-56
-
-
Muller, A.1
Homey, B.2
Soto, H.3
Ge, N.4
Catron, D.5
Buchanan, M.E.6
-
181
-
-
0037154270
-
Activation and inhibition of G protein-coupled receptors by cell-penetrating membrane-tethered peptides
-
L. Covic, A.L. Gresser, J. Talavera, S. Swift, and A. Kuliopulos Activation and inhibition of G protein-coupled receptors by cell-penetrating membrane-tethered peptides Proc Natl Acad Sci USA 99 2002 643 648
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 643-648
-
-
Covic, L.1
Gresser, A.L.2
Talavera, J.3
Swift, S.4
Kuliopulos, A.5
-
182
-
-
79957553894
-
G protein-coupled receptor modulation with pepducins: Moving closer to the clinic
-
P. Dimond, K. Carlson, M. Bouvier, C. Gerard, L. Xu, and L. Covic G protein-coupled receptor modulation with pepducins: moving closer to the clinic Ann N Y Acad Sci 1226 2011 34 49
-
(2011)
Ann N y Acad Sci
, vol.1226
, pp. 34-49
-
-
Dimond, P.1
Carlson, K.2
Bouvier, M.3
Gerard, C.4
Xu, L.5
Covic, L.6
-
183
-
-
84859760355
-
Turning receptors on and off with intracellular pepducins: New insights into G-protein-coupled receptor drug development
-
K. O'Callaghan, A. Kuliopulos, and L. Covic Turning receptors on and off with intracellular pepducins: new insights into G-protein-coupled receptor drug development J Biol Chem 287 2012 12787 12796
-
(2012)
J Biol Chem
, vol.287
, pp. 12787-12796
-
-
O'Callaghan, K.1
Kuliopulos, A.2
Covic, L.3
-
184
-
-
79957744641
-
Interdicting protease-Activated receptor-2-driven inflammation with cell-penetrating pepducins
-
L.M. Sevigny, P. Zhang, A. Bohm, K. Lazarides, G. Perides, and L. Covic Interdicting protease-Activated receptor-2-driven inflammation with cell-penetrating pepducins Proc Natl Acad Sci USA 108 2011 8491 8496
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 8491-8496
-
-
Sevigny, L.M.1
Zhang, P.2
Bohm, A.3
Lazarides, K.4
Perides, G.5
Covic, L.6
-
185
-
-
33846375133
-
Bioinformatic discovery of novel bioactive peptides
-
R.J. Edwards, N. Moran, M. Devocelle, A. Kiernan, G. Meade, and W. Signac Bioinformatic discovery of novel bioactive peptides Nat Chem Biol 3 2007 108 112
-
(2007)
Nat Chem Biol
, vol.3
, pp. 108-112
-
-
Edwards, R.J.1
Moran, N.2
Devocelle, M.3
Kiernan, A.4
Meade, G.5
Signac, W.6
-
186
-
-
78650635767
-
Discovery of a CXCR4 agonist pepducin that mobilizes bone marrow hematopoietic cells
-
B. Tchernychev, Y. Ren, P. Sachdev, J.M. Janz, L. Haggis, and A. O'Shea Discovery of a CXCR4 agonist pepducin that mobilizes bone marrow hematopoietic cells Proc Natl Acad Sci USA 107 2010 22255 22259
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 22255-22259
-
-
Tchernychev, B.1
Ren, Y.2
Sachdev, P.3
Janz, J.M.4
Haggis, L.5
O'Shea, A.6
-
187
-
-
0036797590
-
Pepducin-based intervention of thrombin-receptor signaling and systemic platelet activation
-
L. Covic, M. Misra, J. Badar, C. Singh, and A. Kuliopulos Pepducin-based intervention of thrombin-receptor signaling and systemic platelet activation Nat Med 8 2002 1161 1165
-
(2002)
Nat Med
, vol.8
, pp. 1161-1165
-
-
Covic, L.1
Misra, M.2
Badar, J.3
Singh, C.4
Kuliopulos, A.5
-
188
-
-
20944442051
-
Reversing systemic inflammatory response syndrome with chemokine receptor pepducins
-
N.C. Kaneider, A. Agarwal, A.J. Leger, and A. Kuliopulos Reversing systemic inflammatory response syndrome with chemokine receptor pepducins Nat Med 11 2005 661 665
-
(2005)
Nat Med
, vol.11
, pp. 661-665
-
-
Kaneider, N.C.1
Agarwal, A.2
Leger, A.J.3
Kuliopulos, A.4
-
189
-
-
79551584772
-
Pharmacology, biodistribution, and efficacy of GPCR-based pepducins in disease models
-
S.L. Tressel, G. Koukos, B. Tchernychev, S.L. Jacques, L. Covic, and A. Kuliopulos Pharmacology, biodistribution, and efficacy of GPCR-based pepducins in disease models Methods Mol Biol 683 2011 259 275
-
(2011)
Methods Mol Biol
, vol.683
, pp. 259-275
-
-
Tressel, S.L.1
Koukos, G.2
Tchernychev, B.3
Jacques, S.L.4
Covic, L.5
Kuliopulos, A.6
-
190
-
-
33846474121
-
G-protein-coupled receptors and cancer
-
R.T. Dorsam, and J.S. Gutkind G-protein-coupled receptors and cancer Nat Rev Cancer 7 2007 79 94
-
(2007)
Nat Rev Cancer
, vol.7
, pp. 79-94
-
-
Dorsam, R.T.1
Gutkind, J.S.2
-
191
-
-
0035848718
-
The thrombin receptor, PAR-1, causes transformation by activation of Rho-mediated signaling pathways
-
C.B. Martin, G.M. Mahon, M.B. Klinger, R.J. Kay, M. Symons, and C.J. Der The thrombin receptor, PAR-1, causes transformation by activation of Rho-mediated signaling pathways Oncogene 20 2001 1953 1963
-
(2001)
Oncogene
, vol.20
, pp. 1953-1963
-
-
Martin, C.B.1
Mahon, G.M.2
Klinger, M.B.3
Kay, R.J.4
Symons, M.5
Der, C.J.6
-
192
-
-
54049128201
-
Targeting a metalloprotease-PAR1 signaling system with cell-penetrating pepducins inhibits angiogenesis, ascites, and progression of ovarian cancer
-
A. Agarwal, L. Covic, L.M. Sevigny, N.C. Kaneider, K. Lazarides, and G. Azabdaftari Targeting a metalloprotease-PAR1 signaling system with cell-penetrating pepducins inhibits angiogenesis, ascites, and progression of ovarian cancer Mol Cancer Ther 7 2008 2746 2757
-
(2008)
Mol Cancer Ther
, vol.7
, pp. 2746-2757
-
-
Agarwal, A.1
Covic, L.2
Sevigny, L.M.3
Kaneider, N.C.4
Lazarides, K.5
Azabdaftari, G.6
-
193
-
-
77955022787
-
Identification of a metalloprotease-chemokine signaling system in the ovarian cancer microenvironment: Implications for antiangiogenic therapy
-
A. Agarwal, S.L. Tressel, R. Kaimal, M. Balla, F.H. Lam, and L. Covic Identification of a metalloprotease-chemokine signaling system in the ovarian cancer microenvironment: implications for antiangiogenic therapy Cancer Res 70 2010 5880 5890
-
(2010)
Cancer Res
, vol.70
, pp. 5880-5890
-
-
Agarwal, A.1
Tressel, S.L.2
Kaimal, R.3
Balla, M.4
Lam, F.H.5
Covic, L.6
-
194
-
-
13544255506
-
PAR1 is a matrix metalloprotease-1 receptor that promotes invasion and tumorigenesis of breast cancer cells
-
A. Boire, L. Covic, A. Agarwal, S. Jacques, S. Sherifi, and A. Kuliopulos PAR1 is a matrix metalloprotease-1 receptor that promotes invasion and tumorigenesis of breast cancer cells Cell 120 2005 303 313
-
(2005)
Cell
, vol.120
, pp. 303-313
-
-
Boire, A.1
Covic, L.2
Agarwal, A.3
Jacques, S.4
Sherifi, S.5
Kuliopulos, A.6
-
195
-
-
33745903082
-
Prognostic role of protease-Activated receptors 1 and 4 in resected stage IB non-small-cell lung cancer
-
P. Ghio, S. Cappia, G. Selvaggi, S. Novello, P. Lausi, and G. Zecchina Prognostic role of protease-Activated receptors 1 and 4 in resected stage IB non-small-cell lung cancer Clin Lung Cancer 7 2006 395 400
-
(2006)
Clin Lung Cancer
, vol.7
, pp. 395-400
-
-
Ghio, P.1
Cappia, S.2
Selvaggi, G.3
Novello, S.4
Lausi, P.5
Zecchina, G.6
-
196
-
-
68049143326
-
Blockade of PAR1 signaling with cell-penetrating pepducins inhibits Akt survival pathways in breast cancer cells and suppresses tumor survival and metastasis
-
E. Yang, A. Boire, A. Agarwal, N. Nguyen, K. O'Callaghan, and P. Tu Blockade of PAR1 signaling with cell-penetrating pepducins inhibits Akt survival pathways in breast cancer cells and suppresses tumor survival and metastasis Cancer Res 69 2009 6223 6231
-
(2009)
Cancer Res
, vol.69
, pp. 6223-6231
-
-
Yang, E.1
Boire, A.2
Agarwal, A.3
Nguyen, N.4
O'Callaghan, K.5
Tu, P.6
-
197
-
-
80052443569
-
Targeting protease-Activated receptor-1 with cell-penetrating pepducins in lung cancer
-
J. Cisowski, K. O'Callaghan, A. Kuliopulos, J. Yang, N. Nguyen, and Q. Deng Targeting protease-Activated receptor-1 with cell-penetrating pepducins in lung cancer Am J Pathol 179 2011 513 523
-
(2011)
Am J Pathol
, vol.179
, pp. 513-523
-
-
Cisowski, J.1
O'Callaghan, K.2
Kuliopulos, A.3
Yang, J.4
Nguyen, N.5
Deng, Q.6
-
198
-
-
0141791069
-
MAP kinase-mediated proliferation of DLD-1 carcinoma by the stimulation of protease-Activated receptor 2
-
A. Jikuhara, M. Yoshii, H. Iwagaki, S. Mori, M. Nishibori, and N. Tanaka MAP kinase-mediated proliferation of DLD-1 carcinoma by the stimulation of protease-Activated receptor 2 Life Sci 73 2003 2817 2829
-
(2003)
Life Sci
, vol.73
, pp. 2817-2829
-
-
Jikuhara, A.1
Yoshii, M.2
Iwagaki, H.3
Mori, S.4
Nishibori, M.5
Tanaka, N.6
-
199
-
-
70249123081
-
Met receptor tyrosine kinase transactivation is involved in proteinase-Activated receptor-2-mediated hepatocellular carcinoma cell invasion
-
R. Kaufmann, C. Oettel, A. Horn, K.J. Halbhuber, A. Eitner, and R. Krieg Met receptor tyrosine kinase transactivation is involved in proteinase-Activated receptor-2-mediated hepatocellular carcinoma cell invasion Carcinogenesis 30 2009 1487 1496
-
(2009)
Carcinogenesis
, vol.30
, pp. 1487-1496
-
-
Kaufmann, R.1
Oettel, C.2
Horn, A.3
Halbhuber, K.J.4
Eitner, A.5
Krieg, R.6
-
200
-
-
14644397532
-
A role for protease-Activated receptor-2 in pancreatic cancer cell proliferation
-
R. Shimamoto, T. Sawada, Y. Uchima, M. Inoue, K. Kimura, and Y. Yamashita A role for protease-Activated receptor-2 in pancreatic cancer cell proliferation Int J Oncol 24 2004 1401 1406
-
(2004)
Int J Oncol
, vol.24
, pp. 1401-1406
-
-
Shimamoto, R.1
Sawada, T.2
Uchima, Y.3
Inoue, M.4
Kimura, K.5
Yamashita, Y.6
-
201
-
-
58149232586
-
The interleukin-8 pathway in cancer
-
D.J. Waugh, and C. Wilson The interleukin-8 pathway in cancer Clin Cancer Res 14 2008 6735 6741
-
(2008)
Clin Cancer Res
, vol.14
, pp. 6735-6741
-
-
Waugh, D.J.1
Wilson, C.2
-
202
-
-
0037180757
-
Inflammation and cancer
-
L.M. Coussens, and Z. Werb Inflammation and cancer Nature 420 2002 860 867
-
(2002)
Nature
, vol.420
, pp. 860-867
-
-
Coussens, L.M.1
Werb, Z.2
-
203
-
-
58149465757
-
CXCL8/IL-8 and CXCL12/SDF-1alpha co-operatively promote invasiveness and angiogenesis in pancreatic cancer
-
Y. Matsuo, N. Ochi, H. Sawai, A. Yasuda, H. Takahashi, and H. Funahashi CXCL8/IL-8 and CXCL12/SDF-1alpha co-operatively promote invasiveness and angiogenesis in pancreatic cancer Int J Cancer 124 2009 853 861
-
(2009)
Int J Cancer
, vol.124
, pp. 853-861
-
-
Matsuo, Y.1
Ochi, N.2
Sawai, H.3
Yasuda, A.4
Takahashi, H.5
Funahashi, H.6
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