-
2
-
-
36048947234
-
Breast cancer: Origins and evolution
-
Polyak K. Breast cancer: origins and evolution. J Clin Invest 2007; 117:3155-63.
-
(2007)
J Clin Invest
, vol.117
, pp. 3155-3163
-
-
Polyak, K.1
-
3
-
-
23744452875
-
Loss of TGF-β type II receptor in fibroblasts promotes mammary carcinoma growth and invasion through upregulation of TGF-α-, MSP- and HGF-mediated signaling networks
-
Cheng N, Bhowmick NA, Chytil A, et al. Loss of TGF-β type II receptor in fibroblasts promotes mammary carcinoma growth and invasion through upregulation of TGF-α-, MSP- and HGF-mediated signaling networks. Oncogene 2005;24:5053-68.
-
(2005)
Oncogene
, vol.24
, pp. 5053-5068
-
-
Cheng, N.1
Bhowmick, N.A.2
Chytil, A.3
-
4
-
-
2342441403
-
The stroma as a crucial target in rat mammary gland carcinogenesis
-
Maffini MV, Soto AM, Calabro JM, Ucci AA, Sonnenschein C. The stroma as a crucial target in rat mammary gland carcinogenesis. J Cell Sci 2004;117:1495-502.
-
(2004)
J Cell Sci
, vol.117
, pp. 1495-1502
-
-
Maffini, M.V.1
Soto, A.M.2
Calabro, J.M.3
Ucci, A.A.4
Sonnenschein, C.5
-
5
-
-
34948896045
-
Bone marrow-derived mesenchymal stem cells promote breast cancer metastasis
-
Karnoub AE, Dash AB, Vo AP, et al. Bone marrow-derived mesenchymal stem cells promote breast cancer metastasis. Nature 2007; 449:557-63.
-
(2007)
Nature
, vol.449
, pp. 557-563
-
-
Karnoub, A.E.1
Dash, A.B.2
Vo, A.P.3
-
6
-
-
20144386127
-
Robustness, scalability, and integration of a wound-response gene expression signature in predicting breast cancer survival
-
Chang HY, Nuyten DS, Sneddon JB, et al. Robustness, scalability, and integration of a wound-response gene expression signature in predicting breast cancer survival. Proc Natl Acad Sci U S A 2005; 102:3738-43.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 3738-3743
-
-
Chang, H.Y.1
Nuyten, D.S.2
Sneddon, J.B.3
-
7
-
-
9244227134
-
Stromal fibroblasts in cancer initiation and progression
-
Bhowmick NA, Neilson EG, Moses HL. Stromal fibroblasts in cancer initiation and progression. Nature 2004;432:332-7.
-
(2004)
Nature
, vol.432
, pp. 332-337
-
-
Bhowmick, N.A.1
Neilson, E.G.2
Moses, H.L.3
-
8
-
-
34347374313
-
EGF-R regulates MMP function in fibroblasts through MAPK and AP-1 pathways
-
Kajanne R, Miettinen P, Mehlem A, et al. EGF-R regulates MMP function in fibroblasts through MAPK and AP-1 pathways. J Cell Physiol 2007;212:489-97.
-
(2007)
J Cell Physiol
, vol.212
, pp. 489-497
-
-
Kajanne, R.1
Miettinen, P.2
Mehlem, A.3
-
9
-
-
0034855942
-
Nuclear localization of EGF receptor and its potential new role as a transcription factor
-
Lin SY, Makino K, Xia W, et al. Nuclear localization of EGF receptor and its potential new role as a transcription factor. Nat Cell Biol 2001; 3:802-8.
-
(2001)
Nat Cell Biol
, vol.3
, pp. 802-808
-
-
Lin, S.Y.1
Makino, K.2
Xia, W.3
-
10
-
-
34249845380
-
Characterization of a novel tripartite nuclear localization sequence in the EGFR family
-
Hsu SC, Hung MC. Characterization of a novel tripartite nuclear localization sequence in the EGFR family. J Biol Chem 2007;282: 10432-40.
-
(2007)
J Biol Chem
, vol.282
, pp. 10432-10440
-
-
Hsu, S.C.1
Hung, M.C.2
-
11
-
-
33645217263
-
EGFR signaling pathway in breast cancers: From traditional signal transduction to direct nuclear translocalization
-
Lo HW, Hsu SC, Hung MC. EGFR signaling pathway in breast cancers: from traditional signal transduction to direct nuclear translocalization. Breast Cancer Res Treat 2006;95:211-8.
-
(2006)
Breast Cancer Res Treat
, vol.95
, pp. 211-218
-
-
Lo, H.W.1
Hsu, S.C.2
Hung, M.C.3
-
12
-
-
11244280137
-
Novel prognostic value of nuclear epidermal growth factor receptor in breast cancer
-
Lo HW, Xia W, Wei Y, Ali-Seyed M, Huang SF, Hung MC. Novel prognostic value of nuclear epidermal growth factor receptor in breast cancer. Cancer Res 2005;65:338-48.
-
(2005)
Cancer Res
, vol.65
, pp. 338-348
-
-
Lo, H.W.1
Xia, W.2
Wei, Y.3
Ali-Seyed, M.4
Huang, S.F.5
Hung, M.C.6
-
13
-
-
62549090621
-
Estrogen-related cancer microenvironment of breast carcinoma
-
Yamaguchi Y, Hayashi S. Estrogen-related cancer microenvironment of breast carcinoma. Endocr J 2009;56:1-7.
-
(2009)
Endocr J
, vol.56
, pp. 1-7
-
-
Yamaguchi, Y.1
Hayashi, S.2
-
14
-
-
15744393640
-
Regulation of signal transduction pathways by estrogen and progesterone
-
Edwards DP. Regulation of signal transduction pathways by estrogen and progesterone. Annu Rev Physiol 2005;67:335-76.
-
(2005)
Annu Rev Physiol
, vol.67
, pp. 335-376
-
-
Edwards, D.P.1
-
15
-
-
75149186664
-
The unfolding stories of GPR30, a new membrane bound estrogen receptor
-
Maggiolini M, Picard D. The unfolding stories of GPR30, a new membrane bound estrogen receptor. J Endocrinol 2009;204:105-14.
-
(2009)
J Endocrinol
, vol.204
, pp. 105-114
-
-
Maggiolini, M.1
Picard, D.2
-
16
-
-
3042547161
-
The G protein-coupled receptor GPR30 mediates c-fos up-regulation by 17β-estradiol and phytoestrogens in breast cancer cells
-
Maggiolini M, Vivacqua A, Fasanella G, et al. The G protein-coupled receptor GPR30 mediates c-fos up-regulation by 17β-estradiol and phytoestrogens in breast cancer cells. J Biol Chem 2004;279: 27008-16.
-
(2004)
J Biol Chem
, vol.279
, pp. 27008-27016
-
-
Maggiolini, M.1
Vivacqua, A.2
Fasanella, G.3
-
17
-
-
47949111993
-
EGF induces GPR30 expression in estrogen receptor-negative breast cancer cells
-
Albanito L, Sisci D, Aquila S, et al. EGF induces GPR30 expression in estrogen receptor-negative breast cancer cells. Endocrinology 2008; 149:3799-808.
-
(2008)
Endocrinology
, vol.149
, pp. 3799-3808
-
-
Albanito, L.1
Sisci, D.2
Aquila, S.3
-
18
-
-
33344461590
-
The G protein-coupled receptor GPR30 mediates the proliferative effects induced by 17β-estradiol and hydroxytamoxifen in endometrial cancer cells
-
Vivacqua A, Bonofiglio D, Recchia AG, et al. The G protein-coupled receptor GPR30 mediates the proliferative effects induced by 17β-estradiol and hydroxytamoxifen in endometrial cancer cells. Mol Endocrinol 2006;20:631-46.
-
(2006)
Mol Endocrinol
, vol.20
, pp. 631-646
-
-
Vivacqua, A.1
Bonofiglio, D.2
Recchia, A.G.3
-
19
-
-
70350449695
-
G protein-coupled receptor 30 expression is up-regulated by EGF and TGF α in estrogen receptor α-positive cancer cells
-
Vivacqua A, Lappano R, De Marco P, et al. G protein-coupled receptor 30 expression is up-regulated by EGF and TGF α in estrogen receptor α-positive cancer cells. Mol Endocrinol 2009;23:1815-26.
-
(2009)
Mol Endocrinol
, vol.23
, pp. 1815-1826
-
-
Vivacqua, A.1
Lappano, R.2
De Marco, P.3
-
20
-
-
14844343093
-
A transmembrane intracellular estrogen receptor mediates rapid cell signaling
-
Revankar CM, Cimino DF, Sklar LA, Arterburn JB, Prossnitz ER. A transmembrane intracellular estrogen receptor mediates rapid cell signaling. Science 2005;307:1625-30.
-
(2005)
Science
, vol.307
, pp. 1625-1630
-
-
Revankar, C.M.1
Cimino, D.F.2
Sklar, L.A.3
Arterburn, J.B.4
Prossnitz, E.R.5
-
21
-
-
33847755409
-
G protein-coupled receptor 30 (GPR30) mediates gene expression changes and growth response to 17β-estradiol and selective GPR30 ligand G-1 in ovarian cancer cells
-
Albanito L, Madeo A, Lappano R, et al. G protein-coupled receptor 30 (GPR30) mediates gene expression changes and growth response to 17β-estradiol and selective GPR30 ligand G-1 in ovarian cancer cells. Cancer Res 2007;67:1859-66.
-
(2007)
Cancer Res
, vol.67
, pp. 1859-1866
-
-
Albanito, L.1
Madeo, A.2
Lappano, R.3
-
22
-
-
33748923143
-
17β-Estradiol, genistein and 4-hydroxytamoxifen induce the proliferation of thyroid cancer cells through the G protein-coupled receptor GPR30
-
Vivacqua A, Bonofiglio D, Albanito L, et al. 17β-Estradiol, genistein and 4-hydroxytamoxifen induce the proliferation of thyroid cancer cells through the G protein-coupled receptor GPR30. Mol Pharmacol 2006;70:1414-23.
-
(2006)
Mol Pharmacol
, vol.70
, pp. 1414-1423
-
-
Vivacqua, A.1
Bonofiglio, D.2
Albanito, L.3
-
23
-
-
76249115409
-
The G protein-coupled receptor GPR30 inhibits proliferation of estrogen receptor-positive breast cancer cells
-
Ariazi EA, Brailoiu E, Yerrum S, et al. The G protein-coupled receptor GPR30 inhibits proliferation of estrogen receptor-positive breast cancer cells. Cancer Res 2010;70:1184-94.
-
(2010)
Cancer Res
, vol.70
, pp. 1184-1194
-
-
Ariazi, E.A.1
Brailoiu, E.2
Yerrum, S.3
-
24
-
-
33751272253
-
Distribution of GPR30, a seven membrane-spanning estrogen receptor, in primary breast cancer and its association with clinico-pathologic determinants of tumor progression
-
Filardo EJ, Graeber CT, Quinn JA, et al. Distribution of GPR30, a seven membrane-spanning estrogen receptor, in primary breast cancer and its association with clinico-pathologic determinants of tumor progression. Clin Cancer Res 2006;12:6359-66.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 6359-6366
-
-
Filardo, E.J.1
Graeber, C.T.2
Quinn, J.A.3
-
25
-
-
77955774697
-
GPR30 and estrogen receptor expression: New insights into hormone dependence of inflammatory breast cancer
-
Epub Nov 10
-
Arias-Pulido H, Royce M, Gong Y, et al. GPR30 and estrogen receptor expression: new insights into hormone dependence of inflammatory breast cancer. Breast Cancer Res Treat. Epub 2009 Nov 10.
-
(2009)
Breast Cancer Res Treat
-
-
Arias-Pulido, H.1
Royce, M.2
Gong, Y.3
-
26
-
-
62049084027
-
Estrogenic GPR30 signalling induces proliferation and migration of breast cancer cells through CTGF
-
Pandey DP, Lappano R, Albanito L, Madeo A, Maggiolini M, Picard D. Estrogenic GPR30 signalling induces proliferation and migration of breast cancer cells through CTGF. EMBO J 2009;28:523-32.
-
(2009)
EMBO J
, vol.28
, pp. 523-532
-
-
Pandey, D.P.1
Lappano, R.2
Albanito, L.3
Madeo, A.4
Maggiolini, M.5
Picard, D.6
-
27
-
-
37549035044
-
Connective tissue growth factor is overexpressed in esophageal squamous cell carcinoma and promotes tumorigenicity through β-catenin-T-cell factor/Lef signaling
-
Deng YZ, Chen PP, Wang Y, et al. Connective tissue growth factor is overexpressed in esophageal squamous cell carcinoma and promotes tumorigenicity through β-catenin-T-cell factor/Lef signaling. J Biol Chem 2007;282:36571-81.
-
(2007)
J Biol Chem
, vol.282
, pp. 36571-36581
-
-
Deng, Y.Z.1
Chen, P.P.2
Wang, Y.3
-
28
-
-
44849085062
-
Expression of connective tissue growth factor in tumor tissues is an independent predictor of poor prognosis in patients with gastric cancer
-
Liu LY, Han YC, Wu SH, Lv ZH. Expression of connective tissue growth factor in tumor tissues is an independent predictor of poor prognosis in patients with gastric cancer. World J Gastroenterol 2008;14:2110-4.
-
(2008)
World J Gastroenterol
, vol.14
, pp. 2110-2114
-
-
Liu, L.Y.1
Han, Y.C.2
Wu, S.H.3
Lv, Z.H.4
-
29
-
-
43549127319
-
Expression of connective tissue growth factor (CTGF/CCN2) in head and neck squamous cell carcinoma
-
Mullis TC, Tang X, Chong KT. Expression of connective tissue growth factor (CTGF/CCN2) in head and neck squamous cell carcinoma. J Clin Pathol 2008;61:606-10.
-
(2008)
J Clin Pathol
, vol.61
, pp. 606-610
-
-
Mullis, T.C.1
Tang, X.2
Chong, K.T.3
-
30
-
-
0038488950
-
A multigenic program mediating breast cancer metastasis to bone
-
Kang Y, Siegel PM, Shu W, et al. A multigenic program mediating breast cancer metastasis to bone. Cancer Cell 2003;3:537-49.
-
(2003)
Cancer Cell
, vol.3
, pp. 537-549
-
-
Kang, Y.1
Siegel, P.M.2
Shu, W.3
-
31
-
-
40749094918
-
SATB1 reprogrammes gene expression to promote breast tumour growth and metastasis
-
Han HJ, Russo J, Kohwi Y, Kohwi-Shigematsu T. SATB1 reprogrammes gene expression to promote breast tumour growth and metastasis. Nature 2008;452:187-93.
-
(2008)
Nature
, vol.452
, pp. 187-193
-
-
Han, H.J.1
Russo, J.2
Kohwi, Y.3
Kohwi-Shigematsu, T.4
-
32
-
-
11244333091
-
Differential expression of the CCN family members Cyr61, CTGF and Nov in human breast cancer
-
Jiang WG, Watkins G, Fodstad O, Douglas-Jones A, Mokbel K, Mansel RE. Differential expression of the CCN family members Cyr61, CTGF and Nov in human breast cancer. Endocr Relat Cancer 2004;11:781-91.
-
(2004)
Endocr Relat Cancer
, vol.11
, pp. 781-791
-
-
Jiang, W.G.1
Watkins, G.2
Fodstad, O.3
Douglas-Jones, A.4
Mokbel, K.5
Mansel, R.E.6
-
33
-
-
18844428327
-
Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion
-
Orimo A, Gupta PB, Sgroi DC, et al. Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion. Cell 2005;121:335-48.
-
(2005)
Cell
, vol.121
, pp. 335-348
-
-
Orimo, A.1
Gupta, P.B.2
Sgroi, D.C.3
-
34
-
-
0029877913
-
Activation of the unli-ganded estrogen receptor by EGF involves the MAP kinase pathway and direct phosphorylation
-
Bunone G, Briand PA, Miksicek RJ, Picard D. Activation of the unli-ganded estrogen receptor by EGF involves the MAP kinase pathway and direct phosphorylation. EMBO J 1996;15:2174-83.
-
(1996)
EMBO J
, vol.15
, pp. 2174-2183
-
-
Bunone, G.1
Briand, P.A.2
Miksicek, R.J.3
Picard, D.4
-
35
-
-
77950407928
-
Involvement of estrogen receptor variant ER-{α}36, not GPR30, in nongenomic estrogen signaling
-
Kang L, Zhang X, Xie Y, et al. Involvement of estrogen receptor variant ER-{α}36, not GPR30, in nongenomic estrogen signaling. Mol Endocrinol 2010;24:709-21.
-
(2010)
Mol Endocrinol
, vol.24
, pp. 709-721
-
-
Kang, L.1
Zhang, X.2
Xie, Y.3
-
36
-
-
33646366423
-
Virtual and biomolecular screening converge on a selective agonist for GPR30
-
Bologa CG, Revankar CM, Young SM, et al. Virtual and biomolecular screening converge on a selective agonist for GPR30. Nat Chem Biol 2006;2:207-12.
-
(2006)
Nat Chem Biol
, vol.2
, pp. 207-212
-
-
Bologa, C.G.1
Revankar, C.M.2
Young, S.M.3
-
37
-
-
53249101612
-
The novel estrogen receptor, G protein-coupled receptor 30, mediates the proliferative effects induced by 17β-estradiol on mouse spermatogonial GC-1 cell line
-
Sirianni R, Chimento A, Ruggiero C, et al. The novel estrogen receptor, G protein-coupled receptor 30, mediates the proliferative effects induced by 17β-estradiol on mouse spermatogonial GC-1 cell line. Endocrinology 2008;149:5043-51.
-
(2008)
Endocrinology
, vol.149
, pp. 5043-5051
-
-
Sirianni, R.1
Chimento, A.2
Ruggiero, C.3
-
38
-
-
58149331109
-
G-protein-coupled receptor 30 and estrogen receptor-α are involved in the proliferative effects induced by atrazine in ovarian cancer cells
-
Albanito L, Lappano R, Madeo A, et al. G-protein-coupled receptor 30 and estrogen receptor-α are involved in the proliferative effects induced by atrazine in ovarian cancer cells. Environ Health Perspect 2008;116:1648-55.
-
(2008)
Environ Health Perspect
, vol.116
, pp. 1648-1655
-
-
Albanito, L.1
Lappano, R.2
Madeo, A.3
-
39
-
-
34547789280
-
The interactions between GPR30 and the major biomarkers in infiltrating ductal carcinoma of the breast in an Asian population
-
Kuo WH, Chang LY, Liu DL, et al. The interactions between GPR30 and the major biomarkers in infiltrating ductal carcinoma of the breast in an Asian population. Taiwan J Obstet Gynecol 2007;46: 135-45.
-
(2007)
Taiwan J Obstet Gynecol
, vol.46
, pp. 135-145
-
-
Kuo, W.H.1
Chang, L.Y.2
Liu, D.L.3
-
40
-
-
33947697810
-
GPR30: A novel indicator of poor survival for endometrial carcinoma
-
discussion 386.e9-11
-
Smith HO, Leslie KK, Singh M, et al. GPR30: a novel indicator of poor survival for endometrial carcinoma. Am J Obstet Gynecol 2007;196, 386.e1-9; discussion 386.e9-11.
-
(2007)
Am J Obstet Gynecol
, vol.196
-
-
Smith, H.O.1
Leslie, K.K.2
Singh, M.3
-
41
-
-
67749119671
-
GPR30 predicts poor survival for ovarian cancer
-
Smith HO, Arias-Pulido H, Kuo DY, et al. GPR30 predicts poor survival for ovarian cancer. Gynecol Oncol 2009;114:465-71.
-
(2009)
Gynecol Oncol
, vol.114
, pp. 465-471
-
-
Smith, H.O.1
Arias-Pulido, H.2
Kuo, D.Y.3
-
42
-
-
67349105361
-
Mechanisms of estrogen signaling and gene expression via GPR30
-
Prossnitz ER, Maggiolini M. Mechanisms of estrogen signaling and gene expression via GPR30. Mol Cell Endocrinol 2009;308:32-8.
-
(2009)
Mol Cell Endocrinol
, vol.308
, pp. 32-38
-
-
Prossnitz, E.R.1
Maggiolini, M.2
-
43
-
-
48949116158
-
ERK phosphorylation: Spatial and temporal regulation by G protein-coupled receptors
-
May LT, Hill SJ. ERK phosphorylation: spatial and temporal regulation by G protein-coupled receptors. Int J Biochem Cell Biol 2008;40: 2013-7.
-
(2008)
Int J Biochem Cell Biol
, vol.40
, pp. 2013-2017
-
-
May, L.T.1
Hill, S.J.2
-
44
-
-
33845886924
-
Dynamic regulation of ERK2 nuclear translocation and mobility in living cells
-
Costa M, Marchi M, Cardarelli F, et al. Dynamic regulation of ERK2 nuclear translocation and mobility in living cells. J Cell Sci 2006;119: 4952-63.
-
(2006)
J Cell Sci
, vol.119
, pp. 4952-4963
-
-
Costa, M.1
Marchi, M.2
Cardarelli, F.3
-
46
-
-
33846531356
-
The tumour microenvironment as a target for chemoprevention
-
Albini A, Sporn MB. The tumour microenvironment as a target for chemoprevention. Nat Rev Cancer 2007;7:139-47.
-
(2007)
Nat Rev Cancer
, vol.7
, pp. 139-147
-
-
Albini, A.1
Sporn, M.B.2
-
47
-
-
43249121177
-
Stromal gene expression predicts clinical outcome in breast cancer
-
Finak G, Bertos N, Pepin F, et al. Stromal gene expression predicts clinical outcome in breast cancer. Nat Med 2008;14:518-27.
-
(2008)
Nat Med
, vol.14
, pp. 518-527
-
-
Finak, G.1
Bertos, N.2
Pepin, F.3
-
48
-
-
37549056583
-
Adjuvant letrozole versus tamoxifen according to centrally-assessed ERBB2 status for postmenopausal women with endocrine-responsive early breast cancer: Supplementary results from the BIG 1-98 randomised trial
-
Rasmussen BB, Regan MM, Lykkesfeldt AE, et al. Adjuvant letrozole versus tamoxifen according to centrally-assessed ERBB2 status for postmenopausal women with endocrine-responsive early breast cancer: supplementary results from the BIG 1-98 randomised trial. Lancet Oncol 2008;9:23-8.
-
(2008)
Lancet Oncol
, vol.9
, pp. 23-28
-
-
Rasmussen, B.B.1
Regan, M.M.2
Lykkesfeldt, A.E.3
|