-
1
-
-
3042822267
-
Cancer and the chemokine network
-
Balkwill F. Cancer and the chemokine network. Nat Rev Cancer 2004;4:540-50.
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 540-550
-
-
Balkwill, F.1
-
2
-
-
58149465757
-
CXCL8/IL-8 and CXCL12/SDF-1α co-operatively promote invasiveness and angiogenesis in pancreatic cancer
-
Matsuo Y, Ochi N, Sawai H, et al. CXCL8/IL-8 and CXCL12/SDF-1α co-operatively promote invasiveness and angiogenesis in pancreatic cancer. Int J Cancer 2009;124:853-61.
-
(2009)
Int J Cancer
, vol.124
, pp. 853-861
-
-
Matsuo, Y.1
Ochi, N.2
Sawai, H.3
-
4
-
-
67649440886
-
The biology of ovarian cancer: New opportunities for translation
-
Bast RC, Jr., Hennessy B, Mills GB. The biology of ovarian cancer: new opportunities for translation. Nat Rev Cancer 2009;9:415-28.
-
(2009)
Nat Rev Cancer
, vol.9
, pp. 415-428
-
-
Bast Jr., R.C.1
Hennessy, B.2
Mills, G.B.3
-
5
-
-
0025784990
-
Epithelial ovarian cancer: A cytokine propelled disease?
-
Malik S, Balkwill F. Epithelial ovarian cancer: a cytokine propelled disease? Br J Cancer 1991;64:617-20.
-
(1991)
Br J Cancer
, vol.64
, pp. 617-620
-
-
Malik, S.1
Balkwill, F.2
-
6
-
-
0036554735
-
Analysis of chemokines and chemokine receptor expression in ovarian cancer ascites
-
Milliken D, Scotton C, Raju S, Balkwill F, Wilson J. Analysis of chemokines and chemokine receptor expression in ovarian cancer ascites. Clin Cancer Res 2002;8:1108-14.
-
(2002)
Clin Cancer Res
, vol.8
, pp. 1108-1114
-
-
Milliken, D.1
Scotton, C.2
Raju, S.3
Balkwill, F.4
Wilson, J.5
-
7
-
-
0028960487
-
The detection and localization of monocyte chemoattractant protein-1 (MCP-1) in human ovarian cancer
-
Negus RP, Stamp GW, Relf MG, et al. The detection and localization of monocyte chemoattractant protein-1 (MCP-1) in human ovarian cancer. J Clin Invest 1995;95:2391-6.
-
(1995)
J Clin Invest
, vol.95
, pp. 2391-2396
-
-
Negus, R.P.1
Stamp, G.W.2
Relf, M.G.3
-
8
-
-
0037180757
-
Inflammation and cancer
-
Coussens LM, Werb Z. Inflammation and cancer. Nature 2002;420:860-7.
-
(2002)
Nature
, vol.420
, pp. 860-867
-
-
Coussens, L.M.1
Werb, Z.2
-
9
-
-
0031768087
-
Selective presence of the chemokine growth-regulated oncogene α (GROα) in the human follicle and secretion from cultured granulosalutein cells at ovulation
-
Karstrom-Encrantz L, Runesson E, Bostrom EK, Brannstrom M. Selective presence of the chemokine growth-regulated oncogene α (GROα) in the human follicle and secretion from cultured granulosalutein cells at ovulation. Mol Hum Reprod 1998;4:1077-83.
-
(1998)
Mol Hum Reprod
, vol.4
, pp. 1077-1083
-
-
Karstrom-Encrantz, L.1
Runesson, E.2
Bostrom, E.K.3
Brannstrom, M.4
-
10
-
-
33745890935
-
Circulating IL-8 and anti-IL-8 autoantibody in patients with ovarian cancer
-
Lokshin AE, Winans M, Landsittel D, et al. Circulating IL-8 and anti-IL-8 autoantibody in patients with ovarian cancer. Gynecol Oncol 2006;102:244-51.
-
(2006)
Gynecol Oncol
, vol.102
, pp. 244-251
-
-
Lokshin, A.E.1
Winans, M.2
Landsittel, D.3
-
11
-
-
41049113475
-
NF-κB genes have a major role in inflammatory breast cancer
-
Lerebours F, Vacher S, Andrieu C, et al. NF-κB genes have a major role in inflammatory breast cancer. BMC Cancer 2008;8:41.
-
(2008)
BMC Cancer
, vol.8
, pp. 41
-
-
Lerebours, F.1
Vacher, S.2
Andrieu, C.3
-
12
-
-
40949126550
-
Effect of interleukin-8 gene silencing with liposome-encapsulated small interfering RNA on ovarian cancer cell growth
-
Merritt WM, Lin YG, Spannuth WA, et al. Effect of interleukin-8 gene silencing with liposome-encapsulated small interfering RNA on ovarian cancer cell growth. J Natl Cancer Inst 2008;100:359-72.
-
(2008)
J Natl Cancer Inst
, vol.100
, pp. 359-372
-
-
Merritt, W.M.1
Lin, Y.G.2
Spannuth, W.A.3
-
13
-
-
0037443760
-
IL-8 directly enhanced endothelial cell survival, proliferation, and matrix metalloproteinases production and regulated angiogenesis
-
Li A, Dubey S, Varney ML, Dave BJ, Singh RK. IL-8 directly enhanced endothelial cell survival, proliferation, and matrix metalloproteinases production and regulated angiogenesis. J Immunol 2003;170:3369-76.
-
(2003)
J Immunol
, vol.170
, pp. 3369-3376
-
-
Li, A.1
Dubey, S.2
Varney, M.L.3
Dave, B.J.4
Singh, R.K.5
-
14
-
-
4944265244
-
Gene expression profiling of tumor-stromal interactions between pancreatic cancer cells and stromal fibroblasts
-
Sato N, Maehara N, Goggins M. Gene expression profiling of tumor-stromal interactions between pancreatic cancer cells and stromal fibroblasts. Cancer Res 2004;64:6950-6.
-
(2004)
Cancer Res
, vol.64
, pp. 6950-6956
-
-
Sato, N.1
Maehara, N.2
Goggins, M.3
-
15
-
-
33750798741
-
The chemokine growth-regulated oncogene 1 (Gro-1) links RAS signaling to the senescence of stromal fibroblasts and ovarian tumorigenesis
-
Yang G, Rosen DG, Zhang Z, et al. The chemokine growth-regulated oncogene 1 (Gro-1) links RAS signaling to the senescence of stromal fibroblasts and ovarian tumorigenesis. Proc Natl Acad Sci U S A 2006;103:16472-7.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 16472-16477
-
-
Yang, G.1
Rosen, D.G.2
Zhang, Z.3
-
16
-
-
33646246400
-
Growth-regulated oncogene is pivotal in thrombin-induced angiogenesis
-
Caunt M, Hu L, Tang T, Brooks PC, Ibrahim S, Karpatkin S. Growth-regulated oncogene is pivotal in thrombin-induced angiogenesis. Cancer Res 2006;66:4125-32.
-
(2006)
Cancer Res
, vol.66
, pp. 4125-4132
-
-
Caunt, M.1
Hu, L.2
Tang, T.3
Brooks, P.C.4
Ibrahim, S.5
Karpatkin, S.6
-
17
-
-
0034648757
-
Thrombin signalling and protease-activated receptors
-
Coughlin SR. Thrombin signalling and protease-activated receptors. Nature 2000;407:258-64.
-
(2000)
Nature
, vol.407
, pp. 258-264
-
-
Coughlin, S.R.1
-
18
-
-
0031927754
-
Thrombin receptor over-expression in malignant and physiological invasion processes
-
Even-Ram S, Uziely B, Cohen P, et al. Thrombin receptor over-expression in malignant and physiological invasion processes. Nat Med 1998;4:909-14.
-
(1998)
Nat Med
, vol.4
, pp. 909-914
-
-
Even-Ram, S.1
Uziely, B.2
Cohen, P.3
-
19
-
-
0032533268
-
Protease-activated receptor 1 (PAR-1) is required and rate-limiting for thrombin-enhanced experimental pulmonary metastasis
-
Nierodzik ML, Chen K, Takeshita K, et al. Protease-activated receptor 1 (PAR-1) is required and rate-limiting for thrombin-enhanced experimental pulmonary metastasis. Blood 1998;92:3694-700.
-
(1998)
Blood
, vol.92
, pp. 3694-3700
-
-
Nierodzik, M.L.1
Chen, K.2
Takeshita, K.3
-
20
-
-
0035421226
-
Signaling from protease-activated receptor-1 inhibits migration and invasion of breast cancer cells
-
Kamath L, Meydani A, Foss F, Kuliopulos A. Signaling from protease-activated receptor-1 inhibits migration and invasion of breast cancer cells. Cancer Res 2001;61:5933-40.
-
(2001)
Cancer Res
, vol.61
, pp. 5933-5940
-
-
Kamath, L.1
Meydani, A.2
Foss, F.3
Kuliopulos, A.4
-
21
-
-
0013197528
-
Role and regulation of the thrombin receptor (PAR-1) in human melanoma
-
Tellez C, Bar-Eli M. Role and regulation of the thrombin receptor (PAR-1) in human melanoma. Oncogene 2003;22:3130-7.
-
(2003)
Oncogene
, vol.22
, pp. 3130-3137
-
-
Tellez, C.1
Bar-Eli, M.2
-
22
-
-
13544255506
-
PAR1 is a matrix metalloprotease-1 receptor that promotes invasion and tumorigenesis of breast cancer cells
-
Boire A, Covic L, Agarwal A, Jacques S, Sherifi S, Kuliopulos A. PAR1 is a matrix metalloprotease-1 receptor that promotes invasion and tumorigenesis of breast cancer cells. Cell 2005;120:303-13.
-
(2005)
Cell
, vol.120
, pp. 303-313
-
-
Boire, A.1
Covic, L.2
Agarwal, A.3
Jacques, S.4
Sherifi, S.5
Kuliopulos, A.6
-
23
-
-
54049128201
-
Targeting a metalloprotease-PAR1 signaling system with cell-penetrating pepducins inhibits angiogenesis, ascites, and progression of ovarian cancer
-
Agarwal A, Covic L, Sevigny LM, et al. Targeting a metalloprotease-PAR1 signaling system with cell-penetrating pepducins inhibits angiogenesis, ascites, and progression of ovarian cancer. Mol Cancer Ther 2008;7:2746-57.
-
(2008)
Mol Cancer Ther
, vol.7
, pp. 2746-2757
-
-
Agarwal, A.1
Covic, L.2
Sevigny, L.M.3
-
24
-
-
47949089905
-
Persistent transactivation of EGFR and ErbB2/HER2 by protease-activated receptor-1 promotes breast carcinoma cell invasion
-
Arora P, Cuevas BD, Russo A, Johnson GL, Trejo J. Persistent transactivation of EGFR and ErbB2/HER2 by protease-activated receptor-1 promotes breast carcinoma cell invasion. Oncogene 2008;27:4434-45.
-
(2008)
Oncogene
, vol.27
, pp. 4434-4445
-
-
Arora, P.1
Cuevas, B.D.2
Russo, A.3
Johnson, G.L.4
Trejo, J.5
-
25
-
-
64249129547
-
Platelet matrix metalloprotease-1 mediates thrombogenesis by activating PAR1 at a cryptic ligand site
-
Trivedi V, Boire A, Tchernychev B, et al. Platelet matrix metalloprotease-1 mediates thrombogenesis by activating PAR1 at a cryptic ligand site. Cell 2009;137:332-43.
-
(2009)
Cell
, vol.137
, pp. 332-343
-
-
Trivedi, V.1
Boire, A.2
Tchernychev, B.3
-
26
-
-
33645085566
-
Tumor-derived Cyr61 (CCN1) promotes stromal matrix metalloproteinase-1 production and protease-activated receptor 1-dependent migration of breast cancer cells
-
Nguyen N, Kuliopulos A, Graham RA, Covic L. Tumor-derived Cyr61 (CCN1) promotes stromal matrix metalloproteinase-1 production and protease-activated receptor 1-dependent migration of breast cancer cells. Cancer Res 2006;66:2658-65.
-
(2006)
Cancer Res
, vol.66
, pp. 2658-2665
-
-
Nguyen, N.1
Kuliopulos, A.2
Graham, R.A.3
Covic, L.4
-
27
-
-
68049143326
-
Blockade of PAR1 signaling with cell-penetrating pepducins inhibits Akt survival pathways in breast cancer cells and suppresses tumor survival and metastasis
-
Yang E, Boire A, Agarwal A, et al. Blockade of PAR1 signaling with cell-penetrating pepducins inhibits Akt survival pathways in breast cancer cells and suppresses tumor survival and metastasis. Cancer Res 2009;69:6223-31.
-
(2009)
Cancer Res
, vol.69
, pp. 6223-6231
-
-
Yang, E.1
Boire, A.2
Agarwal, A.3
-
28
-
-
20944442051
-
Reversing systemic inflammatory response syndrome with chemokine receptor pepducins
-
Kaneider NC, Agarwal A, Leger AJ, Kuliopulos A. Reversing systemic inflammatory response syndrome with chemokine receptor pepducins. Nat Med 2005;11:661-5.
-
(2005)
Nat Med
, vol.11
, pp. 661-665
-
-
Kaneider, N.C.1
Agarwal, A.2
Leger, A.J.3
Kuliopulos, A.4
-
29
-
-
0037154270
-
Activation and inhibition of G protein-coupled receptors by cell-penetrating membrane-tethered peptides
-
Covic L, Gresser AL, Talavera J, Swift S, Kuliopulos A. Activation and inhibition of G protein-coupled receptors by cell-penetrating membrane-tethered peptides. Proc Natl Acad Sci U S A 2002;99:643-8.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 643-648
-
-
Covic, L.1
Gresser, A.L.2
Talavera, J.3
Swift, S.4
Kuliopulos, A.5
-
30
-
-
0036797590
-
Pepducin-based intervention of thrombin-receptor signaling and systemic platelet activation
-
Covic L, Misra M, Badar J, Singh C, Kuliopulos A. Pepducin-based intervention of thrombin-receptor signaling and systemic platelet activation. Nat Med 2002;8:1161-5.
-
(2002)
Nat Med
, vol.8
, pp. 1161-1165
-
-
Covic, L.1
Misra, M.2
Badar, J.3
Singh, C.4
Kuliopulos, A.5
-
31
-
-
3042697202
-
Thrombin induces neoangiogenesis in the chick chorioallantoic membrane
-
Caunt M, Huang YQ, Brooks PC, Karpatkin S. Thrombin induces neoangiogenesis in the chick chorioallantoic membrane. J Thromb Haemost 2003;1:2097-102.
-
(2003)
J Thromb Haemost
, vol.1
, pp. 2097-2102
-
-
Caunt, M.1
Huang, Y.Q.2
Brooks, P.C.3
Karpatkin, S.4
-
32
-
-
0041328272
-
The agonist of the protease-activated receptor-1 (PAR) but not PAR3 mimics thrombin-induced vascular endothelial growth factor release in human smooth muscle cells
-
Arisato T, Sarker KP, Kawahara K, et al. The agonist of the protease-activated receptor-1 (PAR) but not PAR3 mimics thrombin-induced vascular endothelial growth factor release in human smooth muscle cells. Cell Mol Life Sci 2003;60:1716-24.
-
(2003)
Cell Mol Life Sci
, vol.60
, pp. 1716-1724
-
-
Arisato, T.1
Sarker, K.P.2
Kawahara, K.3
-
33
-
-
13044257730
-
Design, synthesis, and biological characterization of a peptide-mimetic antagonist for a tethered-ligand receptor
-
Andrade-Gordon P, Maryanoff BE, Derian CK, et al. Design, synthesis, and biological characterization of a peptide-mimetic antagonist for a tethered-ligand receptor. Proc Natl Acad Sci U S A 1999;96:12257-62.
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 12257-12262
-
-
Andrade-Gordon, P.1
Maryanoff, B.E.2
Derian, C.K.3
-
34
-
-
36249020418
-
"Role reversal" for the receptor PAR1 in sepsis-induced vascular damage
-
Kaneider NC, Leger AJ, Agarwal A, et al. "Role reversal" for the receptor PAR1 in sepsis-induced vascular damage. Nat Immunol 2007;8:1303-12.
-
(2007)
Nat Immunol
, vol.8
, pp. 1303-1312
-
-
Kaneider, N.C.1
Leger, A.J.2
Agarwal, A.3
-
35
-
-
0036213048
-
Role of the PAR4 thrombin receptor in stabilizing platelet-platelet aggregates as revealed by a patient with Hermansky-Pudlak syndrome
-
Covic L, Singh C, Smith H, Kuliopulos A. Role of the PAR4 thrombin receptor in stabilizing platelet-platelet aggregates as revealed by a patient with Hermansky-Pudlak syndrome. Thromb Haemost 2002;87:722-7.
-
(2002)
Thromb Haemost
, vol.87
, pp. 722-727
-
-
Covic, L.1
Singh, C.2
Smith, H.3
Kuliopulos, A.4
-
36
-
-
33645507738
-
Blocking the protease-activated receptor 1-4 heterodimer in platelet-mediated thrombosis
-
Leger AJ, Jacques SL, Badar J, et al. Blocking the protease-activated receptor 1-4 heterodimer in platelet-mediated thrombosis. Circulation 2006;113:1244-54.
-
(2006)
Circulation
, vol.113
, pp. 1244-1254
-
-
Leger, A.J.1
Jacques, S.L.2
Badar, J.3
-
37
-
-
33747871452
-
Tumor-derived matrix metalloproteinase-1 targets endothelial proteinase-activated receptor 1 promoting endothelial cell activation
-
Goerge T, Barg A, Schnaeker EM, et al. Tumor-derived matrix metalloproteinase-1 targets endothelial proteinase-activated receptor 1 promoting endothelial cell activation. Cancer Res 2006;66:7766-74.
-
(2006)
Cancer Res
, vol.66
, pp. 7766-7774
-
-
Goerge, T.1
Barg, A.2
Schnaeker, E.M.3
-
38
-
-
67649421573
-
Matrix metalloproteinase-1 promotes breast cancer angiogenesis and osteolysis in a novel in vivo model
-
Eck SM, Hoopes PJ, Petrella BL, Coon CI, Brinckerhoff CE. Matrix metalloproteinase-1 promotes breast cancer angiogenesis and osteolysis in a novel in vivo model. Breast Cancer Res Treat 2009;116:79-90.
-
(2009)
Breast Cancer Res Treat
, vol.116
, pp. 79-90
-
-
Eck, S.M.1
Hoopes, P.J.2
Petrella, B.L.3
Coon, C.I.4
Brinckerhoff, C.E.5
-
39
-
-
24044522259
-
Autocrine role of interleukin-8 in induction of endothelial cell proliferation, survival, migration and MMP-2 production and angiogenesis
-
Li A, Varney ML, Valasek J, Godfrey M, Dave BJ, Singh RK. Autocrine role of interleukin-8 in induction of endothelial cell proliferation, survival, migration and MMP-2 production and angiogenesis. Angiogenesis 2005;8:63-71.
-
(2005)
Angiogenesis
, vol.8
, pp. 63-71
-
-
Li, A.1
Varney, M.L.2
Valasek, J.3
Godfrey, M.4
Dave, B.J.5
Singh, R.K.6
-
40
-
-
34447502449
-
Experience with bevacizumab in the management of epithelial ovarian cancer
-
Burger RA. Experience with bevacizumab in the management of epithelial ovarian cancer. J Clin Oncol 2007;25:2902-8.
-
(2007)
J Clin Oncol
, vol.25
, pp. 2902-2908
-
-
Burger, R.A.1
-
42
-
-
37549040613
-
Paclitaxel plus bevacizumab versus paclitaxel alone for metastatic breast cancer
-
Miller K, Wang M, Gralow J, et al. Paclitaxel plus bevacizumab versus paclitaxel alone for metastatic breast cancer. N Engl J Med 2007;357:2666-76.
-
(2007)
N Engl J Med
, vol.357
, pp. 2666-2676
-
-
Miller, K.1
Wang, M.2
Gralow, J.3
-
43
-
-
0035071510
-
Molecular determinants of ovarian cancer plasticity
-
Sood AK, Seftor EA, Fletcher MS, et al. Molecular determinants of ovarian cancer plasticity. Am J Pathol 2001;158:1279-88.
-
(2001)
Am J Pathol
, vol.158
, pp. 1279-1288
-
-
Sood, A.K.1
Seftor, E.A.2
Fletcher, M.S.3
-
44
-
-
67549104876
-
Expression of urokinase plasminogen activator and its receptor in advanced epithelial ovarian cancer patients
-
Wang L, Madigan MC, Chen H, et al. Expression of urokinase plasminogen activator and its receptor in advanced epithelial ovarian cancer patients. Gynecol Oncol 2009;114:265-72.
-
(2009)
Gynecol Oncol
, vol.114
, pp. 265-272
-
-
Wang, L.1
Madigan, M.C.2
Chen, H.3
-
46
-
-
71349087406
-
A matrix metalloproteinase-1/protease activated receptor-1 signaling axis promotes melanoma invasion and metastasis
-
Blackburn JS, Liu I, Coon CI, Brinckerhoff CE. A matrix metalloproteinase-1/protease activated receptor-1 signaling axis promotes melanoma invasion and metastasis. Oncogene 2009;28:4237-48.
-
(2009)
Oncogene
, vol.28
, pp. 4237-4248
-
-
Blackburn, J.S.1
Liu, I.2
Coon, C.I.3
Brinckerhoff, C.E.4
-
47
-
-
37049036163
-
Transactivation of vascular endothelial growth factor receptor-2 by interleukin-8 (IL-8/CXCL8) is required for IL-8/CXCL8-induced endothelial permeability
-
Petreaca ML, Yao M, Liu Y, Defea K, Martins-Green M. Transactivation of vascular endothelial growth factor receptor-2 by interleukin-8 (IL-8/CXCL8) is required for IL-8/CXCL8-induced endothelial permeability. Mol Biol Cell 2007;18:5014-23.
-
(2007)
Mol Biol Cell
, vol.18
, pp. 5014-5023
-
-
Petreaca, M.L.1
Yao, M.2
Liu, Y.3
Defea, K.4
Martins-Green, M.5
-
48
-
-
1242296871
-
Rho activity critically and selectively regulates endothelial cell organization during angiogenesis
-
Hoang MV, Whelan MC, Senger DR. Rho activity critically and selectively regulates endothelial cell organization during angiogenesis. Proc Natl Acad Sci U S A 2004;101:1874-9.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 1874-1879
-
-
Hoang, M.V.1
Whelan, M.C.2
Senger, D.R.3
-
49
-
-
59449084872
-
Maintenance treatment with bevacizumab prolongs survival in an in vivo ovarian cancer model
-
Mabuchi S, Terai Y, Morishige K, et al. Maintenance treatment with bevacizumab prolongs survival in an in vivo ovarian cancer model. Clin Cancer Res 2008;14:7781-9.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 7781-7789
-
-
Mabuchi, S.1
Terai, Y.2
Morishige, K.3
-
50
-
-
2942615257
-
The anti-angiogenic basis of metronomic chemotherapy
-
Kerbel RS, Kamen BA. The anti-angiogenic basis of metronomic chemotherapy. Nat Rev Cancer 2004;4:423-36.
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 423-436
-
-
Kerbel, R.S.1
Kamen, B.A.2
|