-
1
-
-
2642572647
-
Aging biology and geriatric clinical pharmacology
-
McLean AJ, Le Couter DG. Aging biology and geriatric clinical pharmacology. Pharmacol Rev 2004; 56: 163-84
-
(2004)
Pharmacol Rev
, vol.56
, pp. 163-184
-
-
McLean, A.J.1
Le Couter, D.G.2
-
2
-
-
0033015230
-
The epidemiology of serious adverse drug reactions among the elderly
-
Atkin PA, Veitch PC, Veitch EM, et al. The epidemiology of serious adverse drug reactions among the elderly. Drugs Aging 1999; 14 (2): 141-52
-
(1999)
Drugs Aging
, vol.14
, Issue.2
, pp. 141-152
-
-
Atkin, P.A.1
Veitch, P.C.2
Veitch, E.M.3
-
3
-
-
84860869658
-
Incidence and predictors of adverse drug reactions caused by drug-drug interactions in elderly outpatients: A prospective cohort study
-
Obreli Neto PR, Nobili A, de Lyra Júnior DP, et al. Incidence and predictors of adverse drug reactions caused by drug-drug interactions in elderly outpatients: a prospective cohort study. J Pharm Pharmaceut Sci 2012; 15 (2): 332-43 (www.cspsCanada.org)
-
(2012)
J Pharm Pharmaceut Sci
, vol.15
, Issue.2
, pp. 332-343
-
-
Obreli Neto, P.R.1
Nobili, A.2
De Lyra Jr., D.P.3
-
5
-
-
0036904903
-
Adverse drug reactions as cause of hospital admissions: Results from the Italian Group of Pharmacoepidemiology in the Elderly (GIFA)
-
Dec
-
Onder G, Pedone C, Landi F, et al. Adverse drug reactions as cause of hospital admissions: results from the Italian Group of Pharmacoepidemiology in the Elderly (GIFA). J Am Geriatr Soc 2002 Dec; 50 (12): 1962-8
-
(2002)
J Am Geriatr Soc
, vol.50
, Issue.12
, pp. 1962-1968
-
-
Onder, G.1
Pedone, C.2
Landi, F.3
-
6
-
-
84857853686
-
Adverse drug reaction-related hospitalizations in persons aged 55 years and over: A population-based study in the Netherlands
-
Mar
-
Ruiter R, Visser LE, Rodenburg EM, et al. Adverse drug reaction-related hospitalizations in persons aged 55 years and over: a population-based study in the Netherlands. Drugs Aging 2012 Mar; 29 (3): 225-32
-
(2012)
Drugs Aging
, vol.29
, Issue.3
, pp. 225-232
-
-
Ruiter, R.1
Visser, L.E.2
Rodenburg, E.M.3
-
7
-
-
84864134728
-
Adverse drug reactions in a population of hospitalized very elderly patients
-
Aug
-
Tangiisuran B, Davies JG, Wright JE, et al. Adverse drug reactions in a population of hospitalized very elderly patients. Drugs Aging 2012 Aug; 29 (8): 669-79
-
(2012)
Drugs Aging
, vol.29
, Issue.8
, pp. 669-679
-
-
Tangiisuran, B.1
Davies, J.G.2
Wright, J.E.3
-
8
-
-
80053610820
-
Adverse drug reactions (ADRs) associated with hospital admissions-elderly female patients are at highest risk
-
Oct
-
Hofer-Dueckelmann C, Prinz E, Beindl W, et al. Adverse drug reactions (ADRs) associated with hospital admissions-elderly female patients are at highest risk. Int J Clin Pharmacol Ther 2011 Oct; 49 (10): 577-86
-
(2011)
Int J Clin Pharmacol Ther
, vol.49
, Issue.10
, pp. 577-586
-
-
Hofer-Dueckelmann, C.1
Prinz, E.2
Beindl, W.3
-
9
-
-
84864675995
-
Adverse drug reactions in older patients: An Italian observational prospective hospital study
-
Conforti A, Costantini D, Zanetti F, et al. Adverse drug reactions in older patients: an Italian observational prospective hospital study. Drug Healthc Patient Saf 2012; 4: 75-80
-
(2012)
Drug Healthc Patient Saf
, vol.4
, pp. 75-80
-
-
Conforti, A.1
Costantini, D.2
Zanetti, F.3
-
10
-
-
84864117968
-
Effects of a drug minimization guide on prescribing intentions in elderly persons with polypharmacy
-
Scott IA, Gray LC, Martin JH, et al. Effects of a drug minimization guide on prescribing intentions in elderly persons with polypharmacy. Drugs Aging 2012; 29: 659-67
-
(2012)
Drugs Aging
, vol.29
, pp. 659-667
-
-
Scott, I.A.1
Gray, L.C.2
Martin, J.H.3
-
11
-
-
0001355595
-
The hemolytic effect of primaquine. VII. Biochemical studies of drugsensitive erythrocytes
-
Beutler E, Dern RJ, Flanagan CL, et al. The hemolytic effect of primaquine. VII. Biochemical studies of drugsensitive erythrocytes. J Lab Clin Med 1955; 45: 286-95
-
(1955)
J Lab Clin Med
, vol.45
, pp. 286-295
-
-
Beutler, E.1
Dern, R.J.2
Flanagan, C.L.3
-
12
-
-
35748961114
-
Identifying genetic risk factors for serious adverse drug reactions: Current progress and challenges
-
Wilke RA, Lin DW, Roden DM, et al. Identifying genetic risk factors for serious adverse drug reactions: current progress and challenges. Nat Rev Drug Discov 2007; 6: 904-16
-
(2007)
Nat Rev Drug Discov
, vol.6
, pp. 904-916
-
-
Wilke, R.A.1
Lin, D.W.2
Roden, D.M.3
-
13
-
-
84873820754
-
-
American Association of Pharmaceutical Scientists[Accessed 2011Sep 9]
-
American Association of Pharmaceutical Scientists. Pharmacogenomics (PGx) Focus Group. https://www.aapsj.org/inside/focus-groups/PGX/index.asp.[Accessed 2011Sep 9]
-
-
-
-
14
-
-
84873857120
-
Note for guidance on definitions for genomic biomarkers, pharmacogenomics, pharmacogenetics, genomic data and sample coding categories. EMEA/CHMP/ICH/437986/2006
-
November
-
Note for guidance on definitions for genomic biomarkers, pharmacogenomics, pharmacogenetics, genomic data and sample coding categories. EMEA/CHMP/ICH/437986/2006. November 2007 from the ICH Topic E15 Definitions for genomic biomarkers, pharmacogenomics, pharmacogenetics, genomic data and sample coding categories. http://www.ema.europa.eu/docs/en-GB/document-library/ Scientific-guideline/2009/09/WC500002880.pdf
-
(2007)
ICH Topic E15 Definitions for Genomic Biomarkers, Pharmacogenomics, Pharmacogenetics, Genomic Data and Sample Coding Categories
-
-
-
15
-
-
0033569516
-
Pharmacogenomics: Translating functional genomics into rational therapeutics
-
Evans WE, Relling MV. Pharmacogenomics: translating functional genomics into rational therapeutics. Science 1999; 286 (5439): 487-91
-
(1999)
Science
, vol.286
, Issue.5439
, pp. 487-491
-
-
Evans, W.E.1
Relling, M.V.2
-
16
-
-
0842263894
-
Pharmacogenetics and pharmacogenomics: Are they still promising?
-
Apr
-
Pirazzoli A, Recchia G. Pharmacogenetics and pharmacogenomics: are they still promising? Pharmacol Res 2004 Apr; 49 (4): 357-61
-
(2004)
Pharmacol Res
, vol.49
, Issue.4
, pp. 357-361
-
-
Pirazzoli, A.1
Recchia, G.2
-
17
-
-
77953922472
-
Pharmacogenomics: Bridgingthe gap between science and practice
-
Jan-Feb, quiz e15-17
-
Lee KC, Ma JD, Kuo GM. Pharmacogenomics: bridgingthe gap between science and practice. J Am Pharm Assoc (2003) 2010 Jan-Feb; 50 (1): e1-14; quiz e15-17
-
(2010)
J Am Pharm Assoc (2003)
, vol.50
, Issue.1
-
-
Lee, K.C.1
Ma, J.D.2
Kuo, G.M.3
-
18
-
-
79955685734
-
Clinically relevant genetic variations in drug metabolizing enzymes
-
Jun
-
Pinto N, Dolan ME. Clinically relevant genetic variations in drug metabolizing enzymes. Curr Drug Metab 2011 Jun; 12 (5): 487-97
-
(2011)
Curr Drug Metab
, vol.12
, Issue.5
, pp. 487-497
-
-
Pinto, N.1
Dolan, M.E.2
-
19
-
-
0003495102
-
-
11th Ed. McGraw-Hill, New York City, U.S.
-
Goodman LS, Gilman A, Brunton LL, et al. Goodman & Gilman's thepharmacological basis of therapeutics. 11th ed. McGraw-Hill, New York City, U.S. 2006
-
(2006)
Goodman & Gilman's Thepharmacological Basis of Therapeutics
-
-
Goodman, L.S.1
Gilman, A.2
Brunton, L.L.3
-
20
-
-
80052847569
-
Novel advances in cytochrome P450research
-
Sep
-
Singh D, Kashyap A, Pandey RV, et al. Novel advances in cytochrome P450research. Drug Discov Today 2011 Sep; 16 (17-18): 793-9
-
(2011)
Drug Discov Today
, vol.16
, Issue.17-18
, pp. 793-799
-
-
Singh, D.1
Kashyap, A.2
Pandey, R.V.3
-
21
-
-
0842312531
-
Comparison of cytochrome P450 (CYP) genes from the mouse and human genomes, includingnomenclature recommendations for genes, pseudogenes and alternative-splicevariants
-
Jan
-
Nelson DR, Zeldin DC, Hoffman SM, et al. Comparison of cytochrome P450 (CYP) genes from the mouse and human genomes, includingnomenclature recommendations for genes, pseudogenes and alternative-splicevariants. Pharmacogenetics 2004 Jan; 14 (1): 1-18
-
(2004)
Pharmacogenetics
, vol.14
, Issue.1
, pp. 1-18
-
-
Nelson, D.R.1
Zeldin, D.C.2
Hoffman, S.M.3
-
22
-
-
36148976077
-
Influence ofcytochrome P450 polymorphisms on drug therapies: Pharmacogenetic, pharmacoepigenetic and clinical aspects
-
Dec
-
Ingelman-Sundberg M, Sim SC, Gomez A, et al. Influence ofcytochrome P450 polymorphisms on drug therapies: pharmacogenetic, pharmacoepigenetic and clinical aspects. Pharmacol Ther 2007 Dec; 116 (3): 496-526
-
(2007)
Pharmacol Ther
, vol.116
, Issue.3
, pp. 496-526
-
-
Ingelman-Sundberg, M.1
Sim, S.C.2
Gomez, A.3
-
23
-
-
70049083263
-
Pharmacogenomics and therapeutic strategies for dementia
-
Sep
-
Cacabelos R. Pharmacogenomics and therapeutic strategies for dementia. Expert Rev Mol Diagn 2009 Sep; 9 (6): 567-611
-
(2009)
Expert Rev Mol Diagn
, vol.9
, Issue.6
, pp. 567-611
-
-
Cacabelos, R.1
-
24
-
-
33644658662
-
The clinical and cost-effectiveness of donepezil, rivastigmine, galantamine and memantine for Alzheimer's disease
-
Jan, ix-xi 1-160
-
Loveman E, Green C, Kirby J, et al. The clinical and cost-effectiveness of donepezil, rivastigmine, galantamine and memantine for Alzheimer's disease. Health Technol Assess 2006 Jan; 10 (1): iii-iv, ix-xi, 1-160
-
(2006)
Health Technol Assess
, vol.10
, Issue.1
-
-
Loveman, E.1
Green, C.2
Kirby, J.3
-
25
-
-
70349565396
-
Effect of a CYP2D6 polymorphism on the efficacy of donepezil inpatients with Alzheimer disease
-
Sep
-
Pilotto A, Franceschi M, D'Onofrio G, et al. Effect of a CYP2D6 polymorphism on the efficacy of donepezil inpatients with Alzheimer disease. Neurology 2009 Sep; 73 (10): 761-7
-
(2009)
Neurology
, vol.73
, Issue.10
, pp. 761-767
-
-
Pilotto, A.1
Franceschi, M.2
D'Onofrio, G.3
-
26
-
-
79955452038
-
Role of cytochrome P4502D6 functional polymorphisms in the efficacy of donepezil in patients with Alzheimer's disease
-
Apr
-
Seripa D, Bizzarro A, Pilotto A, et al. Role of cytochrome P4502D6 functional polymorphisms in the efficacy of donepezil in patients with Alzheimer's disease. Pharmacogenet Genomics 2011 Apr; 21 (4): 225-30
-
(2011)
Pharmacogenet Genomics
, vol.21
, Issue.4
, pp. 225-230
-
-
Seripa, D.1
Bizzarro, A.2
Pilotto, A.3
-
27
-
-
80054742063
-
BCHE and CYP2D6 genetic variation in Alzheimer's disease patients treated with cholinesterase inhibitors
-
Chianella C, Gragnaniello D, Maisano Delser P, et al. BCHE and CYP2D6 genetic variation in Alzheimer's disease patients treated with cholinesterase inhibitors. Eur J Clin Pharmacol 2011 Nov; 67 (11): 1147-57
-
Eur J Clin Pharmacol 2011 Nov
, vol.67
, Issue.11
, pp. 1147-1157
-
-
Chianella, C.1
Gragnaniello, D.2
Maisano Delser, P.3
-
28
-
-
74949134529
-
Effects of donepezil galantamine and rivastigmine in 938 Italian patients with Alzheimer's disease: A prospective observational study
-
Feb
-
Santoro A, Siviero P, Minicuci N, et al. Effects of donepezil, galantamine and rivastigmine in 938 Italian patients with Alzheimer's disease: a prospective, observational study. CNS Drugs 2010 Feb; 24 (2): 163-76
-
(2010)
CNS Drugs
, vol.24
, Issue.2
, pp. 163-176
-
-
Santoro, A.1
Siviero, P.2
Minicuci, N.3
-
29
-
-
0027136288
-
Inherited amplification of an active gene in the cytochrome P450CYP2D locus as a cause of ultrarapid metabolism of debrisoquine
-
Dec
-
Johansson I, Lundqvist E, Bertilsson L, et al. Inherited amplification of an active gene in the cytochrome P450CYP2D locus as a cause of ultrarapid metabolism of debrisoquine. Proc Natl Acad SciUSA1993 Dec; 90 (24): 11825-9
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, Issue.24
, pp. 11825-11829
-
-
Johansson, I.1
Lundqvist, E.2
Bertilsson, L.3
-
31
-
-
0242543259
-
Clinical relevance of genetic polymorphisms in the human CYP2C9 gene
-
Schwarz UI. Clinical relevance of genetic polymorphisms in the human CYP2C9 gene. Eur J Clin Investig 2003; 33 Suppl. 2: 23-30
-
(2003)
Eur J Clin Investig
, vol.33
, Issue.SUPPL. 2
, pp. 23-30
-
-
Schwarz, U.I.1
-
32
-
-
11844304376
-
Clinical consequences of cytochrome P450 2C9 polymorphisms
-
Kirchheiner J, Brockmoller J. Clinical consequences of cytochrome P450 2C9 polymorphisms. Clin Pharmacol Ther 2005; 77: 1-16
-
(2005)
Clin Pharmacol Ther
, vol.77
, pp. 1-16
-
-
Kirchheiner, J.1
Brockmoller, J.2
-
33
-
-
0033608466
-
Association of polymorphisms in the cytochrome P450 CYP2C9 with warfarin dose requirement and risk of bleeding complications
-
Feb
-
Aithal GP, Day CP, Kesteven PJ, et al. Association of polymorphisms in the cytochrome P450 CYP2C9 with warfarin dose requirement and risk of bleeding complications. Lancet 1999 Feb; 353 (9154): 717-9
-
(1999)
Lancet
, vol.353
, Issue.9154
, pp. 717-719
-
-
Aithal, G.P.1
Day, C.P.2
Kesteven, P.J.3
-
34
-
-
1542346414
-
Contribution of age, body size, and CYP2C9 genotype to anticoagulant response to warfarin
-
Mar
-
Kamali F, Khan TI, King BP, et al. Contribution of age, body size, and CYP2C9 genotype to anticoagulant response to warfarin. Clin Pharmacol Ther 2004 Mar; 75 (3): 204-12
-
(2004)
Clin Pharmacol Ther
, vol.75
, Issue.3
, pp. 204-212
-
-
Kamali, F.1
Khan, T.I.2
King, B.P.3
-
35
-
-
1642335299
-
Association of pharmacokinetic (CYP2C9) and pharmacodynamic (factors II, VII, IX,and X; Proteins S and C; And gamma-glutamyl carboxylase) gene variants with warfarin sensitivity
-
Apr
-
Shikata E, Ieiri I, Ishiguro S, et al. Association of pharmacokinetic (CYP2C9) and pharmacodynamic (factors II, VII, IX,and X; proteins S and C; and gamma-glutamyl carboxylase) gene variants with warfarin sensitivity. Blood 2004 Apr; 103 (7): 2630-5
-
(2004)
Blood
, vol.103
, Issue.7
, pp. 2630-2635
-
-
Shikata, E.1
Ieiri, I.2
Ishiguro, S.3
-
37
-
-
84872047801
-
Pharmacogenetics in older people: What we know and what we need to know
-
Seripa D, Paroni G, Urbano M, et al. Pharmacogenetics in older people: what we know and what we need to know. J Nephrol 2012; 25 Suppl. 19: 38-47
-
(2012)
J Nephrol
, vol.25
, Issue.SUPPL. 19
, pp. 38-47
-
-
Seripa, D.1
Paroni, G.2
Urbano, M.3
-
38
-
-
0037012465
-
Association between CYP2C9 genetic variants and anticoagulationrelated outcomes during warfarin therapy
-
Apr
-
Higashi MK, Veenstra DL, Kondo LM, et al. Association between CYP2C9 genetic variants and anticoagulationrelated outcomes during warfarin therapy. JAMA 2002 Apr; 287 (13): 1690-8
-
(2002)
JAMA
, vol.287
, Issue.13
, pp. 1690-1698
-
-
Higashi, M.K.1
Veenstra, D.L.2
Kondo, L.M.3
-
39
-
-
59649117935
-
The largest prospective warfarin-treated cohort supports genetic forecasting
-
Wadelius M, Chen LY, Lindh JD, et al. The largest prospective warfarin-treated cohort supports genetic forecasting. Blood 2009; 113 (4): 784-92
-
(2009)
Blood
, vol.113
, Issue.4
, pp. 784-792
-
-
Wadelius, M.1
Chen, L.Y.2
Lindh, J.D.3
-
40
-
-
21144448879
-
Effect of VKORC1 haplotypes on transcriptional regulation and warfarin dose
-
Rieder MJ, Reiner AP, Gage BF, et al. Effect of VKORC1 haplotypes on transcriptional regulation and warfarin dose. N Engl J Med 2005; 352 (22): 2285-93
-
(2005)
N Engl J Med
, vol.352
, Issue.22
, pp. 2285-2293
-
-
Rieder, M.J.1
Reiner, A.P.2
Gage, B.F.3
-
41
-
-
34548822941
-
Genetic-based dosing in orthopedic patients beginning warfarin therapy
-
Sep
-
Millican EA, Lenzini PA, Milligan PE, et al. Genetic-based dosing in orthopedic patients beginning warfarin therapy. Blood 2007 Sep; 110 (5): 1511-5
-
(2007)
Blood
, vol.110
, Issue.5
, pp. 1511-1515
-
-
Millican, E.A.1
Lenzini, P.A.2
Milligan, P.E.3
-
42
-
-
49849105411
-
Laboratory and clinical outcomes of pharmacogenetic vs. clinical protocols for warfarin initiation in orthopedicpatients
-
Oct
-
Lenzini PA, Grice GR, Milligan PE, et al. Laboratory and clinical outcomes of pharmacogenetic vs. clinical protocols for warfarin initiation in orthopedicpatients. J Thromb Haemost 2008 Oct; 6 (10): 1655-62
-
(2008)
J Thromb Haemost
, vol.6
, Issue.10
, pp. 1655-1662
-
-
Lenzini, P.A.1
Grice, G.R.2
Milligan, P.E.3
-
43
-
-
60849097257
-
Estimation of the warfarin dose with clinical and pharmacogenetic data
-
International Warfarin Pharmacogenetics Consortium
-
International Warfarin Pharmacogenetics Consortium, Klein TE, Altman RB, et al. Estimation of the warfarin dose with clinical and pharmacogenetic data. N Engl J Med 2009; 360 (8): 753-64
-
(2009)
N Engl J Med
, vol.360
, Issue.8
, pp. 753-764
-
-
Klein, T.E.1
Altman, R.B.2
-
44
-
-
77950353192
-
Pharmacogenetics of coumarinic oral anticoagulants
-
Manolopoulos VG, Ragia G, Tavridou A. Pharmacogenetics of coumarinic oral anticoagulants. Pharmacogenomics 2010; 11 (4): 493-6
-
(2010)
Pharmacogenomics
, vol.11
, Issue.4
, pp. 493-496
-
-
Manolopoulos, V.G.1
Ragia, G.2
Tavridou, A.3
-
45
-
-
72849127064
-
Genetic factors (VKORC1 CYP2C9 EPHX1 and CYP4F2) are predictor variables for warfarin response in very elderly frail inpatients
-
Pautas E, Moreau C, Gouin-Thibault I, et al. Genetic factors (VKORC1, CYP2C9, EPHX1, and CYP4F2) are predictor variables for warfarin response in very elderly, frail inpatients. Clin Pharmacol Ther 2010; 87 (1): 57-64
-
(2010)
Clin Pharmacol Ther
, vol.87
, Issue.1
, pp. 57-64
-
-
Pautas, E.1
Moreau, C.2
Gouin-Thibault, I.3
-
46
-
-
79953331201
-
Predicting the warfarin maintenance dose in elderly inpatients at treatment initiation: Accuracy of dosing algorithms incorporating or not VKORC1/CYP2C9 genotypes
-
Moreau C, Pautas E, Gouin-Thibault I, et al. Predicting the warfarin maintenance dose in elderly inpatients at treatment initiation: accuracy of dosing algorithms incorporating or not VKORC1/CYP2C9 genotypes. J Thromb Haemost 2011; 9 (4): 711-8
-
(2011)
J Thromb Haemost
, vol.9
, Issue.4
, pp. 711-718
-
-
Moreau, C.1
Pautas, E.2
Gouin-Thibault, I.3
-
47
-
-
84873861813
-
Pharmacogenetic tests could be helpful in predicting of VKA maintenance dose in elderly patients at treatment initiation
-
Jul 6. [Epub ahead of print]
-
Kovac MK, Rakicevic LB, Kusic-Tisma JS, et al. Pharmacogenetic tests could be helpful in predicting of VKA maintenance dose in elderly patients at treatment initiation. J Thromb Thrombolysis 2012 Jul 6. [Epub ahead of print]
-
(2012)
J Thromb Thrombolysis
-
-
Kovac, M.K.1
Rakicevic, L.B.2
Kusic-Tisma, J.S.3
-
48
-
-
22844442802
-
Upper gastrointestinal symptoms and therapies in elderly out-patients, users of non-selective NSAIDs or coxibs
-
Pilotto A, Franceschi M, Vitale DF, et al. Upper gastrointestinal symptoms and therapies in elderly out-patients, users of non-selective NSAIDs or coxibs. Aliment Pharmacol Ther 2005; 22 (2): 147-55
-
(2005)
Aliment Pharmacol Ther
, vol.22
, Issue.2
, pp. 147-155
-
-
Pilotto, A.1
Franceschi, M.2
Vitale, D.F.3
-
49
-
-
34547558049
-
Genetic susceptibility to nonsteroidal anti-inflammatory drug-related gastroduodenal bleeding: Role of cytochrome P450 2C9 polymorphisms
-
Pilotto A, Seripa D, Franceschi M, et al. Genetic susceptibility to nonsteroidal anti-inflammatory drug-related gastroduodenal bleeding: role of cytochrome P450 2C9 polymorphisms. Gastroenterology 2007; 133 (2): 465-71
-
(2007)
Gastroenterology
, vol.133
, Issue.2
, pp. 465-471
-
-
Pilotto, A.1
Seripa, D.2
Franceschi, M.3
-
50
-
-
1942421701
-
Pharmacogenetics of cytochrome P450 and its applications in drug therapy: The past, present and future
-
Ingelman-Sundberg M. Pharmacogenetics of cytochrome P450 and its applications in drug therapy: the past, present and future. Trends Pharmacol Sci 2004; 25: 193-200
-
(2004)
Trends Pharmacol Sci
, vol.25
, pp. 193-200
-
-
Ingelman-Sundberg, M.1
-
51
-
-
33745914612
-
Clinical impact of CYP2C19 polymorphism on theaction of proton pump inhibitors: A review of a special problem
-
Klotz U. Clinical impact of CYP2C19 polymorphism on theaction of proton pump inhibitors: a review of a special problem. Int J Clin Pharmacol Ther 2006; 44 (7): 297-302
-
(2006)
Int J Clin Pharmacol Ther
, vol.44
, Issue.7
, pp. 297-302
-
-
Klotz, U.1
-
52
-
-
34247346587
-
Cytochrome p450 polymorphism as a predictor of ovarian toxicity to pulse cyclophosphamide in systemic lupus erythematosus
-
Singh G, Saxena N, Aggarwal A, et al. Cytochrome p450 polymorphism as a predictor of ovarian toxicity to pulse cyclophosphamide in systemic lupus erythematosus. J Rheumatol 2007; 34: 731-3
-
(2007)
J Rheumatol
, vol.34
, pp. 731-733
-
-
Singh, G.1
Saxena, N.2
Aggarwal, A.3
-
53
-
-
0036394942
-
Clinical significance of the cytochrome P450 2C19 genetic polymorphism
-
Desta Z, Zhao X, Shin JG, et al. Clinical significance of the cytochrome P450 2C19 genetic polymorphism. Clin Pharmacokinet 2002; 41: 913-58
-
(2002)
Clin Pharmacokinet
, vol.41
, pp. 913-958
-
-
Desta, Z.1
Zhao, X.2
Shin, J.G.3
-
54
-
-
30344457586
-
A common novel CYP2C19 gene variant causes ultrarapid drug metabolism relevant for the drug response to proton pump inhibitors and antidepressants
-
Jan
-
Sim SC, Risinger C, Dahl ML, et al. A common novel CYP2C19 gene variant causes ultrarapid drug metabolism relevant for the drug response to proton pump inhibitors and antidepressants. Clin Pharmacol Ther 2006 Jan; 79 (1): 103-13
-
(2006)
Clin Pharmacol Ther
, vol.79
, Issue.1
, pp. 103-113
-
-
Sim, S.C.1
Risinger, C.2
Dahl, M.L.3
-
55
-
-
0036795262
-
Effect of cytochrome P4502C19 genotypic differences on cure rates for gastroesophageal reflux disease by lansoprazole
-
Oct
-
Furuta T, Shirai N, Watanabe F, et al. Effect of cytochrome P4502C19 genotypic differences on cure rates for gastroesophageal reflux disease by lansoprazole. Clin Pharmacol Ther 2002 Oct; 72 (4): 453-60
-
(2002)
Clin Pharmacol Ther
, vol.72
, Issue.4
, pp. 453-460
-
-
Furuta, T.1
Shirai, N.2
Watanabe, F.3
-
56
-
-
0037392311
-
The effects of lansoprazole on erosive reflux oesophagitis are influenced by CYP2C19 polymorphism
-
Kawamura M, Ohara S, Koike T, et al. The effects of lansoprazole on erosive reflux oesophagitis are influenced by CYP2C19 polymorphism. Aliment Pharmacol Ther 2003; 17: 965-73
-
(2003)
Aliment Pharmacol Ther
, vol.17
, pp. 965-973
-
-
Kawamura, M.1
Ohara, S.2
Koike, T.3
-
57
-
-
0036935332
-
Treatment of acid-related diseases in the elderly with emphasis on the use of proton pump inhibitors
-
Thjodleifsson B. Treatment of acid-related diseases in the elderly with emphasis on the use of proton pump inhibitors. Drugs Aging 2002; 19 (12): 911-27
-
(2002)
Drugs Aging
, vol.19
, Issue.12
, pp. 911-927
-
-
Thjodleifsson, B.1
-
58
-
-
26944440101
-
The effect of aging on the relationship between the cytochrome P450 2C19 genotype and omeprazole pharmacokinetics
-
Ishizawa Y, Yasui-Furukori N, Takahata T, et al. The effect of aging on the relationship between the cytochrome P450 2C19 genotype and omeprazole pharmacokinetics. Clin Pharmacokinet 2005; 44 (11): 1179-89
-
(2005)
Clin Pharmacokinet
, vol.44
, Issue.11
, pp. 1179-1189
-
-
Ishizawa, Y.1
Yasui-Furukori, N.2
Takahata, T.3
-
59
-
-
78049326068
-
Reduced-function CYP2C19 genotype and risk of adverse clinical outcomes among patients treated with clopidogrel predominantly for PCI: A meta-analysis
-
Mega JL, Simon T, Collet JP, et al. Reduced-function CYP2C19 genotype and risk of adverse clinical outcomes among patients treated with clopidogrel predominantly for PCI: a meta-analysis. JAMA 2010; 304 (16): 1821-30
-
(2010)
JAMA
, vol.304
, Issue.16
, pp. 1821-1830
-
-
Mega, J.L.1
Simon, T.2
Collet, J.P.3
-
60
-
-
78049348037
-
Clopidogrel and the reducedfunction CYP2C19 genetic variant: A limited piece of the overall therapeutic puzzle
-
Fuster V, Sweeny JM. Clopidogrel and the reducedfunction CYP2C19 genetic variant: a limited piece of the overall therapeutic puzzle. JAMA 2010; 304 (16): 1839-40
-
(2010)
JAMA
, vol.304
, Issue.16
, pp. 1839-1840
-
-
Fuster, V.1
Sweeny, J.M.2
-
61
-
-
84861494090
-
Influence of genetic polymorphisms on the effect of high- and standard-dose clopidogrel after percutaneous coronary intervention: The GIFT (Genotype Information and Functional Testing) study
-
May
-
PriceMJ,Murray SS, AngiolilloDJ, et al. Influence of genetic polymorphisms on the effect of high- and standard-dose clopidogrel after percutaneous coronary intervention: the GIFT (Genotype Information and Functional Testing) study. J Am Coll Cardiol 2012 May; 59 (22): 1928-37
-
(2012)
J Am Coll Cardiol
, vol.59
, Issue.22
, pp. 1928-1937
-
-
Price, M.J.1
Murray, S.S.2
Angiolillo, D.J.3
-
62
-
-
84860792104
-
Paraoxonase 1 Q192R variant and clopidogrel efficacy: Fact or fiction?
-
Apr
-
Lewis JP, Shuldiner AR. Paraoxonase 1 Q192R variant and clopidogrel efficacy: fact or fiction? Circ Cardiovasc Genet 2012 Apr; 5 (2): 153-5
-
(2012)
Circ Cardiovasc Genet
, vol.5
, Issue.2
, pp. 153-155
-
-
Lewis, J.P.1
Shuldiner, A.R.2
-
63
-
-
84863294612
-
Influence of paraoxonase-1 Q192R and cytochrome P450 2C19 polymorphisms on clopidogrel response
-
Kreutz RP, Nystrom P, Kreutz Y, et al. Influence of paraoxonase-1 Q192R and cytochrome P450 2C19 polymorphisms on clopidogrel response. Clin Pharmacol 2012; 4: 13-20
-
(2012)
Clin Pharmacol
, vol.4
, pp. 13-20
-
-
Kreutz, R.P.1
Nystrom, P.2
Kreutz, Y.3
-
64
-
-
84863500468
-
PON1 Meta-Analysis Group. Influence of the paraoxonase-1 Q192R genetic variant on clopidogrel responsiveness and recurrent cardiovascular events: A systematic review and metaanalysis
-
Jul
-
Reny JL, Combescure C, Daali Y, et al., PON1 Meta-Analysis Group. Influence of the paraoxonase-1 Q192R genetic variant on clopidogrel responsiveness and recurrent cardiovascular events: a systematic review and metaanalysis. J Thromb Haemost 2012 Jul; 10 (7): 1242-51
-
(2012)
J Thromb Haemost
, vol.10
, Issue.7
, pp. 1242-1251
-
-
Reny, J.L.1
Combescure, C.2
Daali, Y.3
-
65
-
-
69049095976
-
PON1 is a longevity gene: Results of a meta-analysis
-
Oct
-
Lescai F, Marchegiani F, Franceschi C. PON1 is a longevity gene: results of a meta-analysis. Ageing Res Rev 2009 Oct; 8 (4): 277-84
-
(2009)
Ageing Res Rev
, vol.8
, Issue.4
, pp. 277-284
-
-
Lescai, F.1
Marchegiani, F.2
Franceschi, C.3
-
66
-
-
70349728399
-
Paraoxonase2 C311S polymorphism and low levels of HDL contribute to a higher mortality risk after acute myocardial infarction in elderly patients
-
Nov
-
Marchegiani F, Spazzafumo L, Provinciali M, et al. Paraoxonase2 C311S polymorphism and low levels of HDL contribute to a higher mortality risk after acute myocardial infarction in elderly patients. Mol Genet Metab 2009 Nov; 98 (3): 314-8
-
(2009)
Mol Genet Metab
, vol.98
, Issue.3
, pp. 314-318
-
-
Marchegiani, F.1
Spazzafumo, L.2
Provinciali, M.3
-
67
-
-
84873808527
-
Paraoxonase- 1 55 LL genotype is associated with no STelevation myocardial infarction and with high levels of myoglobin
-
Marchegiani F, Spazzafumo L, Cardelli M, et al. Paraoxonase- 1 55 LL genotype is associated with no STelevation myocardial infarction and with high levels of myoglobin. J Lipids 2012; 2012: 601796
-
(2012)
J Lipids
, vol.2012
, pp. 601796
-
-
Marchegiani, F.1
Spazzafumo, L.2
Cardelli, M.3
-
68
-
-
39449136466
-
Paraoxonase 1: Genetics and activities during aging
-
Feb
-
Marchegiani F, Marra M, Olivieri F, et al. Paraoxonase 1: genetics and activities during aging. Rejuvenation Res 2008 Feb; 11 (1): 113-27
-
(2008)
Rejuvenation Res
, vol.11
, Issue.1
, pp. 113-127
-
-
Marchegiani, F.1
Marra, M.2
Olivieri, F.3
-
69
-
-
12944281041
-
Amitriptyline or not, that is the question: Pharmacogenetic testing of CYP2D6 and CYP2C19 identifies patients with low or high risk for side effects in amitriptyline therapy
-
Steimer W, Zopf K, von Amelunxen S, et al. Amitriptyline or not, that is the question: pharmacogenetic testing of CYP2D6 and CYP2C19 identifies patients with low or high risk for side effects in amitriptyline therapy. Clin Chem 2005; 51: 376-85
-
(2005)
Clin Chem
, vol.51
, pp. 376-385
-
-
Steimer, W.1
Zopf, K.2
Von Amelunxen, S.3
-
70
-
-
84862600938
-
Clinical Pharmacogenomics Implementation Consortium (CPIC). The clinical pharmacogenomics implementation consortium: CPIC guideline for SLCO1B1 and simvastatin-induced myopathy
-
Jul
-
Wilke RA, Ramsey LB, Johnson SG, et al., Clinical Pharmacogenomics Implementation Consortium (CPIC). The clinical pharmacogenomics implementation consortium: CPIC guideline for SLCO1B1 and simvastatin-induced myopathy. Clin Pharmacol Ther 2012 Jul; 92 (1): 112-7
-
(2012)
Clin Pharmacol Ther
, vol.92
, Issue.1
, pp. 112-117
-
-
Wilke, R.A.1
Ramsey, L.B.2
Johnson, S.G.3
-
71
-
-
0036918664
-
Gemfibrozil greatly increases plasma concentrations of cerivastatin
-
Dec
-
Backman JT, Kyrklund C, Neuvonen M, et al. Gemfibrozil greatly increases plasma concentrations of cerivastatin. Clin Pharmacol Ther 2002 Dec; 72 (6): 685-91
-
(2002)
Clin Pharmacol Ther
, vol.72
, Issue.6
, pp. 685-691
-
-
Backman, J.T.1
Kyrklund, C.2
Neuvonen, M.3
-
72
-
-
2942627194
-
Pharmacogenetic study of statin therapy and cholesterol reduction
-
Chasman DI, Posada D, Subrahmanyan L, et al. Pharmacogenetic study of statin therapy and cholesterol reduction. JAMA 2004; 291 (23): 2821-7
-
(2004)
JAMA
, vol.291
, Issue.23
, pp. 2821-2827
-
-
Chasman, D.I.1
Posada, D.2
Subrahmanyan, L.3
-
73
-
-
49149095635
-
Alternative splicing of 3-hydroxy-3-methylglutaryl coenzymeA reductase is associated with plasma low-density lipoprotein cholesterol response to simvastatin
-
Medina MW, Gao F, Ruan W, et al. Alternative splicing of 3-hydroxy-3-methylglutaryl coenzymeA reductase is associated with plasma low-density lipoprotein cholesterol response to simvastatin. Circulation 2008; 118 (4): 355-62
-
(2008)
Circulation
, vol.118
, Issue.4
, pp. 355-362
-
-
Medina, M.W.1
Gao, F.2
Ruan, W.3
-
74
-
-
79953901458
-
Organic anion transporting polypeptide 1B1: A genetically polymorphic transporter of major importance for hepatic druguptake
-
Mar
-
Niemi M, Pasanen MK, Neuvonen PJ. Organic anion transporting polypeptide 1B1: a genetically polymorphic transporter of major importance for hepatic druguptake. Pharmacol Rev 2011 Mar; 63 (1): 157-81
-
(2011)
Pharmacol Rev
, vol.63
, Issue.1
, pp. 157-181
-
-
Niemi, M.1
Pasanen, M.K.2
Neuvonen, P.J.3
-
75
-
-
84855932024
-
Genetic variationat the SLCO1B1 gene locus and low density lipoprotein cholesterol lowering response to pravastatin in the elderly
-
Akao H, Polisecki E, Kajinami K, et al. Genetic variationat the SLCO1B1 gene locus and low density lipoprotein cholesterol lowering response to pravastatin in the elderly. Atherosclerosis 2012; 220 (2): 413-7
-
(2012)
Atherosclerosis
, vol.220
, Issue.2
, pp. 413-417
-
-
Akao, H.1
Polisecki, E.2
Kajinami, K.3
-
76
-
-
49949104757
-
SLCO1B1 variants and statin-inducedmyopathy - A genomewide study
-
Aug
-
SEARCH Collaborative Group, Link E, Parish S, et al. SLCO1B1 variants and statin-inducedmyopathy - a genomewide study. N Engl JMed 2008 Aug; 359 (8): 789-99
-
(2008)
N Engl JMed
, vol.359
, Issue.8
, pp. 789-799
-
-
Link, E.1
Parish, S.2
-
77
-
-
70349739250
-
TheSLCO1B1&z.ast;l5 genetic variant is associated with statin-induced side effects
-
Oct
-
Voora D, Shah SH, Spasojevic I, et al. TheSLCO1B1&z.ast;l5 genetic variant is associated with statin-induced side effects. J AmColl Cardiol 2009 Oct; 54 (17): 1609-16
-
(2009)
J AmColl Cardiol
, vol.54
, Issue.17
, pp. 1609-1616
-
-
Voora, D.1
Shah, S.H.2
Spasojevic, I.3
-
78
-
-
84861459835
-
Differential effect of the rs4149056 variant in SLCO1B1 on myopathy associatedwith simvastatin and atorvastatin
-
Jun
-
Brunham LR, Lansberg PJ, Zhang L, et al. Differential effect of the rs4149056 variant in SLCO1B1 on myopathy associatedwith simvastatin and atorvastatin. Pharmacogenomics J 2012 Jun; 12 (3): 233-7
-
(2012)
Pharmacogenomics J
, vol.12
, Issue.3
, pp. 233-237
-
-
Brunham, L.R.1
Lansberg, P.J.2
Zhang, L.3
-
79
-
-
36549006511
-
Clinical practice. Late-life depression
-
Unützer J. Clinical practice. Late-life depression. N Engl J Med 2007; 357 (22): 2269-75
-
(2007)
N Engl J Med
, vol.357
, Issue.22
, pp. 2269-2275
-
-
Unützer, J.1
-
80
-
-
4344641185
-
The serotonin transporter polymorphism, 5HTTLPR, is associated with a faster response time to sertraline in an elderly population with major depressive disorder
-
Aug
-
Durham LK, Webb SM, Milos PM, et al. The serotonin transporter polymorphism, 5HTTLPR, is associated with a faster response time to sertraline in an elderly population with major depressive disorder. Psychopharmacology (Berl) 2004 Aug; 174 (4): 525-9
-
(2004)
Psychopharmacology (Berl)
, vol.174
, Issue.4
, pp. 525-529
-
-
Durham, L.K.1
Webb, S.M.2
Milos, P.M.3
-
81
-
-
0029895783
-
Allelic variation of human serotonin transporter gene expression
-
Jun
-
Heils A, Teufel A, Petri S, et al. Allelic variation of human serotonin transporter gene expression. J Neurochem 1996 Jun; 66 (6): 2621-4
-
(1996)
J Neurochem
, vol.66
, Issue.6
, pp. 2621-2624
-
-
Heils, A.1
Teufel, A.2
Petri, S.3
-
82
-
-
58149195303
-
Pharmacogenetics and the serotonin transporter in late-life depression
-
Dec
-
Gerretsen P, Pollock BG. Pharmacogenetics and the serotonin transporter in late-life depression. Expert Opin Drug Metab Toxicol 2008 Dec; 4 (12): 1465-78
-
(2008)
Expert Opin Drug Metab Toxicol
, vol.4
, Issue.12
, pp. 1465-1478
-
-
Gerretsen, P.1
Pollock, B.G.2
-
83
-
-
33646072813
-
Serotonin transporter promoter gain-of-function genotypes are linked to obsessive-compulsive disorder
-
May
-
Hu XZ, Lipsky RH, Zhu G, et al. Serotonin transporter promoter gain-of-function genotypes are linked to obsessive-compulsive disorder. Am J Hum Genet 2006 May; 78 (5): 815-26
-
(2006)
Am J Hum Genet
, vol.78
, Issue.5
, pp. 815-826
-
-
Hu, X.Z.1
Lipsky, R.H.2
Zhu, G.3
-
84
-
-
0033807374
-
Allelic variation in the serotonin transporter promoter affects onset of paroxetine treatment response in late-life depression
-
Nov
-
Pollock BG, Ferrell RE, Mulsant BH, et al. Allelic variation in the serotonin transporter promoter affects onset of paroxetine treatment response in late-life depression. Neuropsychopharmacology 2000 Nov; 23 (5): 587-90
-
(2000)
Neuropsychopharmacology
, vol.23
, Issue.5
, pp. 587-590
-
-
Pollock, B.G.1
Ferrell, R.E.2
Mulsant, B.H.3
-
85
-
-
41149146056
-
Serotonin transporter genotype interacts with paroxetine plasma levels to influence depression treatment response in geriatric patients
-
Mar
-
Lotrich FE, Pollock BG, Kirshner M, et al. Serotonin transporter genotype interacts with paroxetine plasma levels to influence depression treatment response in geriatric patients. J Psychiatry Neurosci 2008 Mar; 33 (2): 123-30
-
(2008)
J Psychiatry Neurosci
, vol.33
, Issue.2
, pp. 123-130
-
-
Lotrich, F.E.1
Pollock, B.G.2
Kirshner, M.3
-
86
-
-
34347374871
-
Association between a functional serotonin transporter promoter polymorphism and citalopram treatment in adult outpatients with major depression
-
Jul
-
Hu XZ, Rush AJ, Charney D, et al. Association between a functional serotonin transporter promoter polymorphism and citalopram treatment in adult outpatients with major depression. Arch GenPsychiatry 2007 Jul; 64 (7): 783-92
-
(2007)
Arch GenPsychiatry
, vol.64
, Issue.7
, pp. 783-792
-
-
Hu, X.Z.1
Rush, A.J.2
Charney, D.3
-
88
-
-
80052944892
-
Dihydropyrimidine dehydrogenase gene as a major predictor of severe 5-fluorouracil toxicity
-
Sep
-
Amstutz U, Froehlich TK, Largiadèr CR. Dihydropyrimidine dehydrogenase gene as a major predictor of severe 5-fluorouracil toxicity. Pharmacogenomics 2011 Sep; 12 (9): 1321-36
-
(2011)
Pharmacogenomics
, vol.12
, Issue.9
, pp. 1321-1336
-
-
Amstutz, U.1
Froehlich, T.K.2
Largiadèr, C.R.3
-
89
-
-
83855160887
-
Phase II study of pharmacogenetic-tailored therapy in elderly colorectal cancer patients
-
Scartozzi M, Loretelli C, Berardi R, et al. Phase II study of pharmacogenetic-tailored therapy in elderly colorectal cancer patients. Dig Liver Dis 2012; 44 (1): 74-9
-
(2012)
Dig Liver Dis
, vol.44
, Issue.1
, pp. 74-79
-
-
Scartozzi, M.1
Loretelli, C.2
Berardi, R.3
-
90
-
-
76749098737
-
Overview of the immune response
-
Feb
-
Chaplin DD. Overview of the immune response. J Allergy Clin Immunol 2010 Feb; 125 (2 Suppl. 2): S3-23
-
(2010)
J Allergy Clin Immunol
, vol.125
, Issue.2 SUPPL. 2
-
-
Chaplin, D.D.1
-
92
-
-
0035693524
-
Diagnosis and treatment of allergic skin disorders in the elderly
-
Nedorost ST, Stevens SR. Diagnosis and treatment of allergic skin disorders in the elderly. Drugs Aging 2001; 18 (11): 827-35
-
(2001)
Drugs Aging
, vol.18
, Issue.11
, pp. 827-835
-
-
Nedorost, S.T.1
Stevens, S.R.2
-
93
-
-
1842784823
-
Medical genetics: A marker for Stevens-Johnson syndrome
-
Chung WH, Hung SI, Hong HS, et al. Medical genetics: a marker for Stevens-Johnson syndrome. Nature 2004; 428: 486
-
(2004)
Nature
, vol.428
, pp. 486
-
-
Chung, W.H.1
Hung, S.I.2
Hong, H.S.3
-
94
-
-
34248589506
-
Association between HLA-B&z.ast;1502 allele and antiepileptic drug-induced cutaneous reactions in Han Chinese
-
Man CB, Kwan P, Baum L, et al. Association between HLA-B&z.ast;1502 allele and antiepileptic drug-induced cutaneous reactions in Han Chinese. Epilepsia 2007; 48: 1015-8
-
(2007)
Epilepsia
, vol.48
, pp. 1015-1018
-
-
Man, C.B.1
Kwan, P.2
Baum, L.3
-
95
-
-
57449118501
-
Carbamazepine and phenytoin induced Stevens-Johnson syndrome is associated with the HLA-B&z.ast;1502 allele in a Thai population
-
Locharernkul C, Loplumlert J, Limotai C, et al. Carbamazepine and phenytoin induced Stevens-Johnson syndrome is associated with the HLA-B&z.ast;1502 allele in a Thai population. Epilepsia 2008; 49: 2087-91
-
(2008)
Epilepsia
, vol.49
, pp. 2087-2091
-
-
Locharernkul, C.1
Loplumlert, J.2
Limotai, C.3
-
96
-
-
70450205028
-
Association of HLA-B&z.ast;1502 allele and carbamazepine-induced Stevens-Johnson syndrome among Indians
-
Mehta TY, Prajapati LM, Mittal B, et al. Association of HLA-B&z.ast;1502 allele and carbamazepine-induced Stevens-Johnson syndrome among Indians. Indian J Dermatol Venereol Leprol 2009; 75: 579-82
-
(2009)
Indian J Dermatol Venereol Leprol
, vol.75
, pp. 579-582
-
-
Mehta, T.Y.1
Prajapati, L.M.2
Mittal, B.3
-
97
-
-
61549115662
-
JSAR research group HLA -B locus in Japaneses patients treated with antiepileptic or antimicrobial agents
-
Kaniwa N, Saito Y, Aihara M, et al. JSAR research group HLA -B locus in Japaneses patients treated with antiepileptic or antimicrobial agents. Pharmacogenomics 2008; 9: 1617-22
-
(2008)
Pharmacogenomics
, vol.9
, pp. 1617-1622
-
-
Kaniwa, N.1
Saito, Y.2
Aihara, M.3
-
98
-
-
33646934721
-
RegiSCAR Group A marker for Stevens-Johnson syndrome: Ethnicity matters
-
Lonjou C, Thomas L, Borot N, et al. RegiSCAR Group A marker for Stevens-Johnson syndrome: ethnicity matters. Pharmacogenomics J 2006; 6: 265-8
-
(2006)
Pharmacogenomics J
, vol.6
, pp. 265-268
-
-
Lonjou, C.1
Thomas, L.2
Borot, N.3
-
99
-
-
58149250548
-
FDA: Epilepsy drugs may carry skin risks for Asians
-
Kuehn BM. FDA: epilepsy drugs may carry skin risks for Asians. JAMA 2008; 300 (24): 2845
-
(2008)
JAMA
, vol.300
, Issue.24
, pp. 2845
-
-
Kuehn, B.M.1
-
100
-
-
33645082244
-
Genetic susceptibility to carbamazepine-induced cutaneous adverse drug reactions
-
Hung SI, Chung WH, Jee SH, et al. Genetic susceptibility to carbamazepine-induced cutaneous adverse drug reactions. Pharmacogenet Genomics 2006; 16 (4): 297-306
-
(2006)
Pharmacogenet Genomics
, vol.16
, Issue.4
, pp. 297-306
-
-
Hung, S.I.1
Chung, W.H.2
Jee, S.H.3
-
101
-
-
79953197983
-
HLA-A&z.ast;3101 and carbamazepine-induced hypersensitivity reactions in Europeans
-
McCormackM, Alfirevic A, Bourgeois S, et al. HLA-A&z.ast;3101 and carbamazepine-induced hypersensitivity reactions in Europeans. N Engl J Med 2011; 364 (12): 1134-43
-
N Engl J Med 2011
, vol.364
, Issue.12
, pp. 1134-1143
-
-
McCormack, M.1
Alfirevic, A.2
Bourgeois, S.3
-
102
-
-
79551600984
-
Genome-wide association study identifies HLA-A&z.ast;3101 allele as a genetic risk factor for carbamazepine-induced cutaneous adverse drug reactions in Japanese population
-
Ozeki T, Mushiroda T, Yowang A, et al. Genome-wide association study identifies HLA-A&z.ast;3101 allele as a genetic risk factor for carbamazepine-induced cutaneous adverse drug reactions in Japanese population. Hum Mol Genet 2011; 20 (5): 1034-41
-
(2011)
Hum Mol Genet
, vol.20
, Issue.5
, pp. 1034-1041
-
-
Ozeki, T.1
Mushiroda, T.2
Yowang, A.3
-
103
-
-
78650007285
-
HLA-B&z.ast;1511 is a risk factor for carbamazepine-induced Stevens-Johnson syndrome and toxic epidermal necrolysis in Japanese patients
-
Kaniwa N, Saito Y, Aihara M, et al. HLA-B&z.ast;1511 is a risk factor for carbamazepine-induced Stevens-Johnson syndrome and toxic epidermal necrolysis in Japanese patients. Epilepsia 2010; 51 (12): 2461-5
-
(2010)
Epilepsia
, vol.51
, Issue.12
, pp. 2461-2465
-
-
Kaniwa, N.1
Saito, Y.2
Aihara, M.3
-
104
-
-
75649107833
-
HLA class i markers in Japanese patients with carbamazepineinduced cutaneous adverse reactions
-
Ikeda H, Takahashi Y, Yamazaki E, et al. HLA class I markers in Japanese patients with carbamazepineinduced cutaneous adverse reactions. Epilepsia 2010; 51 (2): 297-300
-
(2010)
Epilepsia
, vol.51
, Issue.2
, pp. 297-300
-
-
Ikeda, H.1
Takahashi, Y.2
Yamazaki, E.3
-
105
-
-
15244349566
-
HLA-B&z.ast;5801 allele as a genetic marker for severe cutaneous adverse reactions caused by allopurinol
-
Hung SI, Chung WH, Liou LB, et al. HLA-B&z.ast;5801 allele as a genetic marker for severe cutaneous adverse reactions caused by allopurinol. Proc Natl Acad Sci U S A 2005; 102: 4134-9
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 4134-4139
-
-
Hung, S.I.1
Chung, W.H.2
Liou, L.B.3
-
106
-
-
70249122727
-
Strong association between HLA-B&z.ast;5801 and allopurinol-induced Stevens-Johnson syndrome and toxic epidermal necrolysis in a Thai population
-
Tassaneeyakul W, Jantararoungtong T, Chen P, et al. Strong association between HLA-B&z.ast;5801 and allopurinol-induced Stevens-Johnson syndrome and toxic epidermal necrolysis in a Thai population. Pharmacogenet Genomics 2009; 19: 704-9
-
(2009)
Pharmacogenet Genomics
, vol.19
, pp. 704-709
-
-
Tassaneeyakul, W.1
Jantararoungtong, T.2
Chen, P.3
-
107
-
-
0037006623
-
Association between presence of HLA-B&z.ast;5701, HLA-DR7, and HLA-DQ3 and hypersensitivity to HIV-1 reverse-transcriptase inhibitor abacavir
-
Mallal S, Nolan D, Witt C, et al. Association between presence of HLA-B&z.ast;5701, HLA-DR7, and HLA-DQ3 and hypersensitivity to HIV-1 reverse-transcriptase inhibitor abacavir. Lancet 2002; 359: 727-32
-
(2002)
Lancet
, vol.359
, pp. 727-732
-
-
Mallal, S.1
Nolan, D.2
Witt, C.3
-
108
-
-
0037197044
-
Genetic variations in HLA-B region and hypersensitivity reactions to abacavir
-
Hetherington S, Hughes AR, Mosteller M, et al. Genetic variations in HLA-B region and hypersensitivity reactions to abacavir. Lancet 2002; 359: 1121-2
-
(2002)
Lancet
, vol.359
, pp. 1121-1122
-
-
Hetherington, S.1
Hughes, A.R.2
Mosteller, M.3
-
109
-
-
12144291646
-
Association of genetic variations in HLA-B region with hypersensitivity to abacavir in some, but not all, populations
-
Hughes AR, Mosteller M, Bansal AT, et al. Association of genetic variations in HLA-B region with hypersensitivity to abacavir in some, but not all, populations. Pharmacogenomics 2004; 5: 203-11
-
(2004)
Pharmacogenomics
, vol.5
, pp. 203-211
-
-
Hughes, A.R.1
Mosteller, M.2
Bansal, A.T.3
-
110
-
-
38949196447
-
PREDICT-1 Study Team HLA-B&z.ast;5701 screening for hypersensitivity to abacavir
-
Mallal S, Phillips E, Carosi G, et al. PREDICT-1 Study Team HLA-B&z.ast;5701 screening for hypersensitivity to abacavir. N Engl J Med 2008; 358: 568-79
-
(2008)
N Engl J Med
, vol.358
, pp. 568-579
-
-
Mallal, S.1
Phillips, E.2
Carosi, G.3
-
111
-
-
67649859295
-
DILIGEN Study; International SAE Consortium. HLA-B&z.ast;5701 genotype is a major determinant of drug-induced liver injury due toflucloxacillin
-
Jul
-
Daly AK, Donaldson PT, Bhatnagar P, et al., DILIGEN Study; International SAE Consortium. HLA-B&z.ast;5701 genotype is a major determinant of drug-induced liver injury due toflucloxacillin. Nat Genet 2009 Jul; 41 (7): 816-9
-
(2009)
Nat Genet
, vol.41
, Issue.7
, pp. 816-819
-
-
Daly, A.K.1
Donaldson, P.T.2
Bhatnagar, P.3
-
112
-
-
77955082302
-
A genome-wide study identifies HLA alleles associated with lumiracoxib-related liver injury
-
Aug
-
Singer JB, Lewitzky S, Leroy E, et al. A genome-wide study identifies HLA alleles associated with lumiracoxib-related liver injury. Nat Genet 2010 Aug; 42 (8): 711-4
-
(2010)
Nat Genet
, vol.42
, Issue.8
, pp. 711-714
-
-
Singer, J.B.1
Lewitzky, S.2
Leroy, E.3
-
113
-
-
84862631961
-
In silico analysis of HLA associations with drug-induced liver injury: Use of a HLA-genotyped DNA archive from healthy volunteers
-
Jun
-
Alfirevic A, Gonzalez-Galarza F, Bell C, et al. In silico analysis of HLA associations with drug-induced liver injury: use of a HLA-genotyped DNA archive from healthy volunteers. Genome Med 2012 Jun; 4 (6): 51
-
(2012)
Genome Med
, vol.4
, Issue.6
, pp. 51
-
-
Alfirevic, A.1
Gonzalez-Galarza, F.2
Bell, C.3
-
114
-
-
85027955716
-
The clinical application of UGT1A1 pharmacogenetic testing: Gene-environment interactions
-
Apr
-
Marques SC, Ikediobi ON. The clinical application of UGT1A1 pharmacogenetic testing: gene-environment interactions. Hum Genomics 2010 Apr; 4 (4): 238-49
-
(2010)
Hum Genomics
, vol.4
, Issue.4
, pp. 238-249
-
-
Marques, S.C.1
Ikediobi, O.N.2
-
115
-
-
48949119333
-
Pharmacogenetics of Gilbert's syndrome
-
Strassburg CP. Pharmacogenetics of Gilbert's syndrome. Pharmacogenomics 2008; 9: 703-15
-
(2008)
Pharmacogenomics
, vol.9
, pp. 703-715
-
-
Strassburg, C.P.1
-
116
-
-
47149089807
-
Pharmacogenetic testing for uridine diphosphate glucuronosyltransferase 1A1 polymorphisms: Are we there yet?
-
Perera MA, Innocenti F, Ratain MJ. Pharmacogenetic testing for uridine diphosphate glucuronosyltransferase 1A1 polymorphisms: are we there yet? Pharmacotherapy 2008; 28: 755-68
-
(2008)
Pharmacotherapy
, vol.28
, pp. 755-768
-
-
Perera, M.A.1
Innocenti, F.2
Ratain, M.J.3
-
117
-
-
15244342411
-
UDP-glucuronosyl-transferases and clinical drug-drug interactions
-
Kiang TK, Ensom MH, Chang TK. UDP-glucuronosyl-transferases and clinical drug-drug interactions. Pharmacol Ther 2005; 106: 97-132
-
(2005)
Pharmacol Ther
, vol.106
, pp. 97-132
-
-
Kiang, T.K.1
Ensom, M.H.2
Chang, T.K.3
-
118
-
-
79651470986
-
Pharmacogenomic biomarkers: New tools in current and future drug therapy
-
Feb
-
Sim SC, Ingelman-Sundberg M. Pharmacogenomic biomarkers: new tools in current and future drug therapy. Trends Pharmacol Sci 2011 Feb; 32 (2): 72-81
-
(2011)
Trends Pharmacol Sci
, vol.32
, Issue.2
, pp. 72-81
-
-
Sim, S.C.1
Ingelman-Sundberg, M.2
-
119
-
-
34250304874
-
Clinical pharmacogenomics of thiopurine S-methyl-transferase
-
Jan
-
Zhou S. Clinical pharmacogenomics of thiopurine S-methyl-transferase. Curr Clin Pharmacol 2006 Jan; 1 (1): 119-28
-
(2006)
Curr Clin Pharmacol
, vol.1
, Issue.1
, pp. 119-128
-
-
Zhou, S.1
-
120
-
-
45849107951
-
Clinical pharmacology and pharmacogenetics of thiopurines
-
Aug
-
Sahasranaman S, Howard D, Roy S. Clinical pharmacology and pharmacogenetics of thiopurines. Eur J Clin Pharmacol 2008 Aug; 64 (8): 753-67
-
(2008)
Eur J Clin Pharmacol
, vol.64
, Issue.8
, pp. 753-767
-
-
Sahasranaman, S.1
Howard, D.2
Roy, S.3
-
121
-
-
36049045884
-
Immunosuppressive therapy in older cardiac transplant patients
-
Aliabadi AZ, Zuckermann AO, Grimm M. Immunosuppressive therapy in older cardiac transplant patients. Drugs Aging 2007; 24 (11): 913-32
-
(2007)
Drugs Aging
, vol.24
, Issue.11
, pp. 913-932
-
-
Aliabadi, A.Z.1
Zuckermann, A.O.2
Grimm, M.3
-
122
-
-
65649138698
-
MicroRNA polymorphisms: The future of pharmacogenomics, molecular epidemiology and individualized medicine
-
Mar
-
Mishra PJ, Bertino Jr. MicroRNA polymorphisms: the future of pharmacogenomics, molecular epidemiology and individualized medicine. Pharmacogenomics. 2009 Mar; 10 (3): 399-416
-
(2009)
Pharmacogenomics.
, vol.10
, Issue.3
, pp. 399-416
-
-
Mishra, P.J.1
Bertino, J.R.2
-
123
-
-
37749027621
-
Pharmacogenomics of microRNA: A miRSNP towards individualized therapy
-
Dec
-
Bertino JR, Banerjee D, Mishra PJ. Pharmacogenomics of microRNA: a miRSNP towards individualized therapy. Pharmacogenomics. 2007 Dec; 8 (12): 1625-7
-
(2007)
Pharmacogenomics
, vol.8
, Issue.12
, pp. 1625-1627
-
-
Bertino, J.R.1
Banerjee, D.2
Mishra, P.J.3
-
124
-
-
34548059198
-
A miR-24 microRNA binding-site polymorphism in dihydrofolate reductase gene leads to methotrexate resistance
-
Aug 14
-
Mishra PJ, Humeniuk R, Mishra PJ, et al. A miR-24 microRNA binding-site polymorphism in dihydrofolate reductase gene leads to methotrexate resistance. Proc Natl Acad Sci U S A. 2007 Aug 14; 104 (33): 13513-8
-
(2007)
Proc Natl Acad Sci U S A.
, vol.104
, Issue.33
, pp. 13513-13518
-
-
Mishra, P.J.1
Humeniuk, R.2
Mishra, P.J.3
-
125
-
-
42449110323
-
MiRSNPs or MiR-polymorphisms, new players in microRNA mediated regulation of the cell: Introducing microRNA pharmacogenomics
-
Apr 1
-
Mishra PJ, Mishra PJ, Banerjee D, et al. MiRSNPs or MiR-polymorphisms, new players in microRNA mediated regulation of the cell: introducing microRNA pharmacogenomics. Cell Cycle 2008 Apr 1; 7 (7): 853-8
-
(2008)
Cell Cycle
, vol.7
, Issue.7
, pp. 853-85858
-
-
Mishra, P.J.1
Mishra, P.J.2
Banerjee, D.3
-
127
-
-
83355168713
-
A MiR-200b200c429-binding site polymorphism in the 30 untranslated region of the AP-2a gene is associated with cisplatin resistance
-
2011
-
Wu Y, Xiao Y, Ding X, et al. A miR-200b/200c/429-binding site polymorphism in the 30 untranslated region of the AP-2a gene is associated with cisplatin resistance. PLoS ONE 2011; 6 (12): e29043
-
PLoS ONE
, vol.6
, Issue.12
-
-
Wu, Y.1
Xiao, Y.2
Ding, X.3
-
128
-
-
77949756362
-
Genome-wide association studies in pharmacogenomics
-
Daly AK. Genome-wide association studies in pharmacogenomics. Nat Rev Genet 2010; 11: 241-6
-
(2010)
Nat Rev Genet
, vol.11
, pp. 241-246
-
-
Daly, A.K.1
-
129
-
-
84863914005
-
Recent patents on highthroughput single nucleotide polimorphism (SNP)genotyping methods
-
Paula Careta F, Paneto GG. Recent patents on highthroughput single nucleotide polimorphism (SNP)genotyping methods. Recent Pat DNA Gene Seg 2012; 6: 122-6
-
(2012)
Recent Pat DNA Gene Seg
, vol.6
, pp. 122-126
-
-
Paula Careta, F.1
Paneto, G.G.2
-
130
-
-
84878240242
-
Pharmacogenomics in colorectal cancer: A genome-wide association study to predict toxicity after 5-fluorouracil or FOLFOX administration
-
Feb 7 (Epub ahead of print)
-
Fernandez-Rozadilla C, Cazier JB, Moreno V, et al. Pharmacogenomics in colorectal cancer: a genome-wide association study to predict toxicity after 5-fluorouracil or FOLFOX administration. Pharmacogenomics J 2012 Feb 7 (Epub ahead of print)
-
(2012)
Pharmacogenomics J
-
-
Fernandez-Rozadilla, C.1
Cazier, J.B.2
Moreno, V.3
-
131
-
-
84866415102
-
A genome-wide association study identifies novel loci for paclitaxelinduced sensory peripheral neuropathy in CALGB 40101
-
Sep 15
-
Baldwin RM, Owzar K, Zembutsu H, et al. A genome-wide association study identifies novel loci for paclitaxelinduced sensory peripheral neuropathy in CALGB 40101. Clin Cancer Res 2012 Sep 15; 18 (18): 5099-109
-
(2012)
Clin Cancer Res
, vol.18
, Issue.18
, pp. 5099-5109
-
-
Baldwin, R.M.1
Owzar, K.2
Zembutsu, H.3
-
132
-
-
84860760398
-
Pharmacogenomic study of side-effects for antidepressant treatment options in STAR&z.ast;D
-
Jun
-
Clark SL, Adkins DE, Aberg K, et al. Pharmacogenomic study of side-effects for antidepressant treatment options in STAR&z.ast;D. Psychol Med 2012 Jun; 42 (6): 1151-62
-
(2012)
Psychol Med
, vol.42
, Issue.6
, pp. 1151-1162
-
-
Clark, S.L.1
Adkins, D.E.2
Aberg, K.3
-
133
-
-
80053498680
-
Replication of LDL GWAs hits in PROSPER/PHASE as validation for future (pharmaco)genetic analyses
-
Oct
-
Trompet S, de Craen AJ, Postmus I, et al. Replication of LDL GWAs hits in PROSPER/PHASE as validation for future (pharmaco)genetic analyses. BMC Med Genet 2011 Oct 6; 12: 131
-
(2011)
BMC Med Genet
, vol.6
, Issue.12
, pp. 131
-
-
Trompet, S.1
De Craen, A.J.2
Postmus, I.3
-
134
-
-
63449117825
-
A genomewide association study confirms VKORC1, CYP2C9, and CYP4F2 as principal genetic determinants of warfarin dose
-
Mar
-
Takeuchi F, McGinnis R, Bourgeois S, et al. A genomewide association study confirms VKORC1, CYP2C9, and CYP4F2 as principal genetic determinants of warfarin dose. PLoS Genet 2009 Mar; 5 (3): e1000433
-
(2009)
PLoS Genet
, vol.5
, Issue.3
-
-
Takeuchi, F.1
McGinnis, R.2
Bourgeois, S.3
-
135
-
-
80051564495
-
Genomic technology applied to pharmacological traits
-
Aug 10
-
Yang JJ, Plenge RM. Genomic technology applied to pharmacological traits. JAMA 2011 Aug 10; 306 (6): 652-3
-
(2011)
JAMA
, vol.306
, Issue.6
, pp. 652-653
-
-
Yang, J.J.1
Plenge, R.M.2
-
136
-
-
77949773445
-
ITPA gene variants protect against anaemia in patients treated for chronic hepatitis C
-
Mar 18
-
Fellay J, Thompson AJ, Ge D, et al. ITPA gene variants protect against anaemia in patients treated for chronic hepatitis C. Nature 2010 Mar 18; 464 (7287): 405-8
-
(2010)
Nature
, vol.464
, Issue.7287
, pp. 405-408
-
-
Fellay, J.1
Thompson, A.J.2
Ge, D.3
-
137
-
-
79251612707
-
Common variants near ATM are associated with glycemic response to metformin in type 2 diabetes
-
Feb
-
GoDARTS and UKPDS Diabetes Pharmacogenetics Study Group, Wellcome Trust Case Control Consortium 2, Zhou K, et al. Common variants near ATM are associated with glycemic response to metformin in type 2 diabetes. Nat Genet 2011 Feb; 43 (2): 117-20
-
(2011)
Nat Genet
, vol.43
, Issue.2
, pp. 117-120
-
-
Zhou, K.1
-
138
-
-
59149089672
-
Genome-wide approaches to identify pharmacogenetic contributions to adverse drug reactions
-
Feb
-
Nelson MR, Bacanu SA, Mosteller M, et al. Genome-wide approaches to identify pharmacogenetic contributions to adverse drug reactions. Pharmacogenomics J 2009 Feb; 9 (1): 23-33
-
(2009)
Pharmacogenomics J
, vol.9
, Issue.1
, pp. 23-33
-
-
Nelson, M.R.1
Bacanu, S.A.2
Mosteller, M.3
-
139
-
-
84864118842
-
Optimizing drug outcomes through pharmacogenetics: A case for preemptive genotyping
-
Schildcrout JS, Denny JC, Bowton E, et al. Optimizing drug outcomes through pharmacogenetics: a case for preemptive genotyping. Clinical Pharmacology & Therapeutics 2012; 92: 235-42
-
(2012)
Clinical Pharmacology & Therapeutics
, vol.92
, pp. 235-242
-
-
Schildcrout, J.S.1
Denny, J.C.2
Bowton, E.3
-
140
-
-
70349943777
-
An agenda for personalized medicine
-
Oct 8
-
Ng PC, Murray SS, Levy S, et al. An agenda for personalized medicine. Nature 2009 Oct 8; 461 (7265): 724-6
-
(2009)
Nature
, vol.461
, Issue.7265
, pp. 724-726
-
-
Ng, P.C.1
Murray, S.S.2
Levy, S.3
-
141
-
-
84858322966
-
Pharmacogenetic screening for drug therapy: From single gene markers to decision making in the next generation sequencing era
-
Feb
-
Tzvetkov M, von Ahsen N. Pharmacogenetic screening for drug therapy: from single gene markers to decision making in the next generation sequencing era. Pathology 2012 Feb; 44 (2): 166-80
-
(2012)
Pathology
, vol.44
, Issue.2
, pp. 166-180
-
-
Tzvetkov, M.1
Von Ahsen, N.2
|