HLA-B*5801 allele as a genetic marker for severe cutaneous adverse reactions caused by allopurinol

Proceedings of the National Academy of Sciences of the United States of America

Volumn 102, Issue 11, 2005, Pages 4134-4139

  Hung, Shuen Lu ^a   Chung, Wen Hung ^a,b,i   Liou, Lieh Bang ^b   Chu, Chen Chung ^c   Lin, Marie ^c   Huang, Hsien Ping ^a   Lin, Yen Ling ^a   Lan, Joung Liang ^d   Yang, Li Cheng ^b   Hong, Hong Shang ^b   Chen, Ming Jing ^b   Lai, Ping Chin ^b   Wu, Mai Szu ^b   Chu, Chia Yu ^e,f   Wang, Kuo Hsien ^e,f   Chen, Chien Hsiun ^a   Fann, Cathy S J ^a   Wu, Jer Yuarn ^a,g   Chen, Yuan Tsong ^a,h  

^a INSTITUTE OF BIOMEDICAL SCIENCES   (Taiwan)

^b CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

^c MACKAY MEMORIAL HOSPITAL   (Taiwan)

^d TAICHUNG VETERANS GENERAL HOSPITAL   (Taiwan)

^e NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

^f TAIPEI MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^g CHINA MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^h DUKE UNIVERSITY MEDICAL CENTER   (United States)

ⁱ NATIONAL YANG MING UNIVERSITY   (Taiwan)

Author keywords

Adverse drug reactions; Genetic polymorphism; Pharmacogenetics; Stevens Johnson syndrome; Toxic epidermal necrolysis

Indexed keywords

ALLOPURINOL; HLA B ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; PROTEIN MSH5; PROTEIN MUTS; UNCLASSIFIED DRUG; ANTIGOUT AGENT; HLA B*5801 ANTIGEN, HUMAN; HLA-B*5801 ANTIGEN, HUMAN;

ADULT; AGED; ALLELE; ARTICLE; CONTROLLED STUDY; DRUG METABOLISM; FEMALE; GENE LINKAGE DISEQUILIBRIUM; GENETIC MARKER; GENETIC RISK; GENETIC SCREENING; HAPLOTYPE; HLA B 5801 ALLELE; HUMAN; IMMUNE RESPONSE; MAJOR HISTOCOMPATIBILITY COMPLEX; MALE; PRIORITY JOURNAL; SKIN DISEASE; GENE FREQUENCY; GENETIC PREDISPOSITION; GENETICS; HYPERSENSITIVITY; IMMUNOLOGY; METABOLISM; MIDDLE AGED; SINGLE NUCLEOTIDE POLYMORPHISM;

AGED; AGED, 80 AND OVER; ALLOPURINOL; FEMALE; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GOUT SUPPRESSANTS; HAPLOTYPES; HLA-B ANTIGENS; HUMANS; HYPERSENSITIVITY; MALE; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; SKIN DISEASES;

EID: 15244349566     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0409500102     Document Type: Article

References (36)

1. Wortmann, R. L. (2002) Curr. Opin. Rheumatol. 14, 281-286.
2. Terkeltaub, R. A. (2003) N. Engl. J. Med. 349, 1647-1655.
3. Roujeau, J. C., Kelly, J. P., Naldi, L., Rzany, B., Stern, R. S., Anderson, T., Auquier, A., Bastuji-Garin, S., Correia, O., Locati, F., et al. (1995) N. Engl. J. Med. 333, 1600-1607.
4. Aubock, J. & Fritsch, P. (1985) Br. Med. J. 290, 1969-1970.
5. Arellano, F. & Sacristan, J. A. (1993) Ann. Pharmacother. 27, 337-343.
6. Zanni, M. P., von Greyerz, S., Schnyder, B., Brander, K. A., Frutig, K., Hari, Y., Valitutti, S. & Pichler, W. J. (1998) J. Clin. Invest. 102, 1591-1598.
7. Braden, G. L., Warzynski, M. J., Golightly, M. & Ballow, M. (1994) Clin. Immunol. Immunopathol. 70, 145-151.
8. Melsom, R. D. (1999) Rheumatology (Oxford) 38, 1301.
9. Roujeau, J. C. (1994) J. Invest. Dermatol 102, 28S-30S.
10. Smigielski, E. M., Sirotkin, K., Ward, M. & Sherry, S. T. (2000) Nucleic Acids Res. 28, 352-355.
11. Walsh, E. C., Mather, K. A., Schaffner, S. F., Farwell, L., Daly, M. J., Patterson, N., Cullen, M., Carrington, M., Bugawan, T. L., Erlich, H., et al. (2003) Am. J. Hum. Genet. 73, 580-590.
12. Begovich, A. B. & Erlich, H. A. (1995) J. Am. Med. Assoc. 273, 586-591.
13. Tilanus, M. G. J., Hansen, J. A. & Hurley, C. K., eds. (2002) Genomic Analysis of the Human MHC: DNA-Based Typing for HLA Alleles and Linked Polymorphisms (International Histocompatibility Working Group, Seattle), technical manual.
14. Chu, C. C., Lin, M., Nakajima, F., Lee, H. L., Chang, S. L., Juji, T. & Tokunaga, K. (2001) Tissue Antigens 58, 9-18.
15. Schaid, D. J. & Jacobsen, S. J. (1999) Am. J. Epidemiol. 149, 706-711.
16. Haldane, J. B. (1956) Ann. Hum. Genet. 20, 309-311.
17. Kramer, H. M. & Curhan, G. (2002) Am. J. Kidney Dis. 40, 37-42.
18. Young, J. L., Jr., Boswell, R. B. & Nies, A. S. (1974) Arch. Intern. Med. 134, 553-558.
19. Hildesheim, A., Apple, R. J., Chen, C. J., Wang, S. S., Cheng, Y. J., Klitz, W., Mack, S. J., Chen, I. H., Hsu, M. M., Yang, C. S., et al. (2002) J. Natl. Cancer Inst. 94, 1780-1789.
20. Schlosstein, L., Terasaki, P. I., Bluestone, R. & Pearson, C. M. (1973) N. Engl. J. Med. 288, 704-706.
21. Brewerton, D. A., Hart, F. D., Nicholls, A., Caffrey, M., James, D. C. & Sturrock, R. D. (1973) Lancet 1, 904-907.
22. Geer, L., Terasaki, P. I. & Gjertson, D. W. (1998) in HLA 1998, eds. Gjertson, D.W. & Terasaki, P.I. (Am. Soc. Histocomp. Immunogenet., Mt. Laurel, NJ), pp. 352-353.
23. Hande, K. R., Noone, R. M. & Stone, W. J. (1984) Am. J. Med. 76, 47-56.
24. Vazquez-Mellado, J., Morales, E. M., Pacheco-Tena, C. & Burgos-Vargas, R. (2001) Ann. Rheum. Dis. 60, 981-983.
25. Emmerson, B. T. (1996) N. Engl. J. Med. 334, 445-451.
26. Roujeau, J. C., Bracq, C., Huyn, N. T., Chaussalet, E., Raffin, C. & Duedari, N. (1986) Tissue Antigens 28, 251-254.
27. Roujeau, J. C., Huynh, T. N., Bracq, C., Guillaume, J. C., Revuz, J. & Touraine, R. (1987) Arch. Dermatol. 123, 1171-1173.
28. Shirato, S., Kagaya, F., Suzuki, Y. & Joukou, S. (1997) Arch. Ophthalmol. 115, 550-553.
29. Chan, S. H. & Tan, T. (1989) Dermatologica 179, 32-33.
30. Chung, W. H., Hung, S. I., Hong, H. S., Hsih, M. S., Yang, L. C., Ho, H. C., Wu, J. Y. & Chen, Y. T. (2004) Nature 428, 486.
31. Mallal, S., Nolan, D., Witt, C., Masel, G., Martin, A. M., Moore, C., Sayer, D., Castley, A., Mamotte, C., Maxwell, D., et al. (2002) Lancet 359, 727-732.
32. Martin, A. M., Nolan, D., Gaudieri, S., Almeida, C. A., Nolan, R., James. I., Carvalho, F., Phillips, E., Christiansen, F. T., Purcell, A. W., et al. (2004) Proc. Natl. Acad. Sci. USA 101, 4180-4185.
33. Suzuki, Y., Inagi, R., Aono, T., Yamanishi, K. & Shiohara, T. (1998) Arch. Dermatol. 134, 1108-1112.
34. Srinivasula, S. M., Ahmad, M., Ottilie, S., Bullrich, F., Banks, S., Wang, Y., Fernandes-Alnemri, T., Croce, C. M., Litwack, G., Tomaselli, K. J., et al. (1997) J. Biol. Chem. 272, 18542-18545.
35. Abe, R., Shimizu, T., Shibaki, A., Nakamura, H., Watanabe, H. & Shimizu, H. (2003) Am. J. Pathol. 162, 1515-1520.
36. Gati, A., Guerra, N., Gaudin, C., Da Rocha, S., Escudier, B., Lecluse, Y., Bettaieb, A., Chouaib, S. & Caignard, A. (2003) Cancer Res. 63, 7475-7582.