-
1
-
-
0034619028
-
Adverse drug reactions: Definitions, diagnosis, and management
-
Edwards IR, Aronson JK. Adverse drug reactions: Definitions, diagnosis, and management. Lancet 2000; 356: 1255-1259.
-
(2000)
Lancet
, vol.356
, pp. 1255-1259
-
-
Edwards, I.R.1
Aronson, J.K.2
-
2
-
-
0035338343
-
Risks in new drug development: Approval success rates for investigational drugs
-
Dimasi JA. Risks in new drug development: Approval success rates for investigational drugs. Clin Pharmacol Ther 2001; 69: 297-307.
-
(2001)
Clin Pharmacol Ther
, vol.69
, pp. 297-307
-
-
Dimasi, J.A.1
-
3
-
-
22144474788
-
Adverse drug event surveillance and drug withdrawals in the United States, 1969-2002: The importance of reporting suspected reactions
-
Wysowski DK, Swartz L. Adverse drug event surveillance and drug withdrawals in the United States, 1969-2002: The importance of reporting suspected reactions. Arch Intern Med 2005; 165: 1363-1369.
-
(2005)
Arch Intern Med
, vol.165
, pp. 1363-1369
-
-
Wysowski, D.K.1
Swartz, L.2
-
4
-
-
0032522873
-
Incidence of adverse drug reactions in hospitalized patients: A meta-analysis of prospective studies
-
Lazarou J, Pomeranz BH, Corey PN. Incidence of adverse drug reactions in hospitalized patients: A meta-analysis of prospective studies. JAMA 1998; 279: 1200-1205.
-
(1998)
JAMA
, vol.279
, pp. 1200-1205
-
-
Lazarou, J.1
Pomeranz, B.H.2
Corey, P.N.3
-
5
-
-
3042723720
-
Adverse drug reactions as cause of admission to hospital: Prospective analysis of 18 820 patients
-
Pirmohamed M, James S, Meakin S, Green C, Scott AK, Walley TJ et al. Adverse drug reactions as cause of admission to hospital: Prospective analysis of 18 820 patients. BMJ 2004; 329: 15-19.
-
(2004)
BMJ
, vol.329
, pp. 15-19
-
-
Pirmohamed, M.1
James, S.2
Meakin, S.3
Green, C.4
Scott, A.K.5
Walley, T.J.6
-
6
-
-
33845657889
-
Pharmacogenetics of ABCG2 and adverse reactions to gefitinib
-
Cusatis G, Gregorc V, Li J, Spreafico A, Ingersoll RG, Verweij J et al. Pharmacogenetics of ABCG2 and adverse reactions to gefitinib. J Natl Cancer Inst 2006; 98: 1739-1742.
-
(2006)
J Natl Cancer Inst
, vol.98
, pp. 1739-1742
-
-
Cusatis, G.1
Gregorc, V.2
Li, J.3
Spreafico, A.4
Ingersoll, R.G.5
Verweij, J.6
-
7
-
-
0037380862
-
Cytochrome P450 2E1 genotype and the susceptibility to antituberculosis drug-induced hepatitis
-
Huang YS, Chern HD, Su WJ, Wu JC, Chang SC, Chiang CH et al. Cytochrome P450 2E1 genotype and the susceptibility to antituberculosis drug-induced hepatitis. Hepatology 2003; 37: 924-930.
-
(2003)
Hepatology
, vol.37
, pp. 924-930
-
-
Huang, Y.S.1
Chern, H.D.2
Su, W.J.3
Wu, J.C.4
Chang, S.C.5
Chiang, C.H.6
-
8
-
-
2342459714
-
Genetic variants in the UDP-glucuronosyltransferase 1A1 gene predict the risk of severe neutropenia of irinotecan
-
Innocenti F, Undevia SD, Iyer L, Chen PX, Das S, Kocherginsky M et al. Genetic variants in the UDP-glucuronosyltransferase 1A1 gene predict the risk of severe neutropenia of irinotecan. J Clin Oncol 2004; 22: 1382-1388.
-
(2004)
J Clin Oncol
, vol.22
, pp. 1382-1388
-
-
Innocenti, F.1
Undevia, S.D.2
Iyer, L.3
Chen, P.X.4
Das, S.5
Kocherginsky, M.6
-
9
-
-
4143101374
-
Relevance of different UGT1A1 polymorphisms in irinotecan-induced toxicity: A molecular and clinical study of 75 patients
-
Rouits E, Boisdron-Celle M, Dumont A, Guerin O, Morel A, Gamelin E. Relevance of different UGT1A1 polymorphisms in irinotecan-induced toxicity: A molecular and clinical study of 75 patients. Clin Cancer Res 2004; 10: 5151-5159.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 5151-5159
-
-
Rouits, E.1
Boisdron-Celle, M.2
Dumont, A.3
Guerin, O.4
Morel, A.5
Gamelin, E.6
-
10
-
-
0037197044
-
Genetic variations in HLA-B region and hypersensitivity reactions to abacavir
-
Hetherington S, Hughes AR, Mosteller M, Shortino D, Baker KL, Spreen W et al. Genetic variations in HLA-B region and hypersensitivity reactions to abacavir. Lancet 2002; 359: 1121-1122.
-
(2002)
Lancet
, vol.359
, pp. 1121-1122
-
-
Hetherington, S.1
Hughes, A.R.2
Mosteller, M.3
Shortino, D.4
Baker, K.L.5
Spreen, W.6
-
11
-
-
10744221779
-
A Gilbert's syndrome UGT1A1 variant confers susceptibility to tranilast-induced hyperbilirubinemia
-
Danoff TM, Campbell DA, McCarthy LC, Lewis KF, Repasch MH, Saunders AM et al. A Gilbert's syndrome UGT1A1 variant confers susceptibility to tranilast-induced hyperbilirubinemia. Pharmacogenomics J 2004; 4: 49-53.
-
(2004)
Pharmacogenomics J
, vol.4
, pp. 49-53
-
-
Danoff, T.M.1
Campbell, D.A.2
McCarthy, L.C.3
Lewis, K.F.4
Repasch, M.H.5
Saunders, A.M.6
-
12
-
-
0033486029
-
Mercaptopurine therapy intolerance and heterozygosity at the thiopurine S-methyltransferase gene locus
-
Relling MV, Hancock ML, Rivera GK, Sandlund JT, Ribeiro RC, Krynetski EY et al. Mercaptopurine therapy intolerance and heterozygosity at the thiopurine S-methyltransferase gene locus. J Natl Cancer Inst 1999; 91: 2001-2008.
-
(1999)
J Natl Cancer Inst
, vol.91
, pp. 2001-2008
-
-
Relling, M.V.1
Hancock, M.L.2
Rivera, G.K.3
Sandlund, J.T.4
Ribeiro, R.C.5
Krynetski, E.Y.6
-
13
-
-
15244349566
-
HLA-B*5801 allele as a genetic marker for severe cutaneous adverse reactions caused by allopurinol
-
Hung SI, Chung WH, Liou LB, Chu CC, Lin M, Huang HP et al. HLA-B*5801 allele as a genetic marker for severe cutaneous adverse reactions caused by allopurinol. Proc Natl Acad Sci USA 2005; 102: 4134-4139.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 4134-4139
-
-
Hung, S.I.1
Chung, W.H.2
Liou, L.B.3
Chu, C.C.4
Lin, M.5
Huang, H.P.6
-
14
-
-
1842784823
-
Medical genetics: A marker for Stevens-Johnson syndrome
-
Chung WH, Hung SI, Hong HS, Hsih MS, Yang LC, Ho HC et al. Medical genetics: A marker for Stevens-Johnson syndrome. Nature 2004; 428: 486.
-
(2004)
Nature
, vol.428
, pp. 486
-
-
Chung, W.H.1
Hung, S.I.2
Hong, H.S.3
Hsih, M.S.4
Yang, L.C.5
Ho, H.C.6
-
15
-
-
13544270007
-
Disease-specific target selection: A critical first step down the right road
-
Roses AD, Burns DK, Chissoe S, Middleton L, Jean PS. Disease-specific target selection: A critical first step down the right road. Drug Discov Today 2005; 10: 177-189.
-
(2005)
Drug Discov Today
, vol.10
, pp. 177-189
-
-
Roses, A.D.1
Burns, D.K.2
Chissoe, S.3
Middleton, L.4
Jean, P.S.5
-
17
-
-
12144291646
-
Association of genetic variations in HLA-B region with hypersensitivity to abacavir in some, but not all, populations
-
Hughes AR, Mosteller M, Bansal AT, Davies K, Haneline SA, Lai EH et al. Association of genetic variations in HLA-B region with hypersensitivity to abacavir in some, but not all, populations. Pharmacogenomics 2004; 5: 203-211.
-
(2004)
Pharmacogenomics
, vol.5
, pp. 203-211
-
-
Hughes, A.R.1
Mosteller, M.2
Bansal, A.T.3
Davies, K.4
Haneline, S.A.5
Lai, E.H.6
-
18
-
-
0037006623
-
Association between presence of HLA-B*5701, HLA-DR7, and HLA-DQ3 and hypersensitivity to HIV-1 reverse-transcriptase inhibitor abacavir
-
Mallal S, Nolan D, Witt C, Masel G, Martin AM, Moore C et al. Association between presence of HLA-B*5701, HLA-DR7, and HLA-DQ3 and hypersensitivity to HIV-1 reverse-transcriptase inhibitor abacavir. Lancet 2002; 359: 727-732.
-
(2002)
Lancet
, vol.359
, pp. 727-732
-
-
Mallal, S.1
Nolan, D.2
Witt, C.3
Masel, G.4
Martin, A.M.5
Moore, C.6
-
19
-
-
33749137515
-
A high-resolution HLA and SNP haplotype map for disease association studies in the extended human MHC
-
De Bakker PI, McVean G, Sabeti PC, Miretti MM, Green T, Marchini J et al. A high-resolution HLA and SNP haplotype map for disease association studies in the extended human MHC. Nat Genet 2006; 38: 1166-1172.
-
(2006)
Nat Genet
, vol.38
, pp. 1166-1172
-
-
De Bakker, P.I.1
McVean, G.2
Sabeti, P.C.3
Miretti, M.M.4
Green, T.5
Marchini, J.6
-
22
-
-
33745279392
-
Evaluating and improving power in whole-genome association studies using fixed marker sets
-
Pe'er I, De Bakker PI, Maller J, Yelensky R, Altshuler D, Daly MJ. Evaluating and improving power in whole-genome association studies using fixed marker sets. Nat Genet 2006; 38: 663-667.
-
(2006)
Nat Genet
, vol.38
, pp. 663-667
-
-
Pe'er, I.1
De Bakker, P.I.2
Maller, J.3
Yelensky, R.4
Altshuler, D.5
Daly, M.J.6
-
23
-
-
34347344976
-
A new multipoint method for genome-wide association studies by imputation of genotypes
-
Marchini J, Howie B, Myers S, McVean G, Donnelly P. A new multipoint method for genome-wide association studies by imputation of genotypes. Nat Genet 2007; 39: 906-913.
-
(2007)
Nat Genet
, vol.39
, pp. 906-913
-
-
Marchini, J.1
Howie, B.2
Myers, S.3
McVean, G.4
Donnelly, P.5
-
24
-
-
0035094764
-
Variation is the spice of life
-
Kruglyak L, Nickerson DA. Variation is the spice of life. Nat Genet 2001; 27: 234-236.
-
(2001)
Nat Genet
, vol.27
, pp. 234-236
-
-
Kruglyak, L.1
Nickerson, D.A.2
-
27
-
-
0001677717
-
Controlling the false discovery rate: A practical and powerful approach to multiple testing
-
Benjamini Y, Hochberg Y. Controlling the false discovery rate: A practical and powerful approach to multiple testing. J Roy Statist Soc B 1995; 57: 289-300.
-
(1995)
J Roy Statist Soc B
, vol.57
, pp. 289-300
-
-
Benjamini, Y.1
Hochberg, Y.2
-
28
-
-
0042424602
-
Statistical significance for genomewide studies
-
Storey JD, Tibshirani R. Statistical significance for genomewide studies. Proc Natl Acad Sci USA 2003; 100: 9440-9445.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 9440-9445
-
-
Storey, J.D.1
Tibshirani, R.2
-
29
-
-
84969213492
-
Genome-wide association study of 14 000 cases of seven common diseases and 3000 shared controls
-
Wellcome Trust Case Control Consortium
-
Wellcome Trust Case Control Consortium. Genome-wide association study of 14 000 cases of seven common diseases and 3000 shared controls. Nature 2007; 447: 661-678.
-
(2007)
Nature
, vol.447
, pp. 661-678
-
-
-
30
-
-
0034118493
-
Inference of population structure using multilocus genotype data
-
Pritchard JK, Stephens M, Donnelly P. Inference of population structure using multilocus genotype data. Genetics 2000; 155: 945-959.
-
(2000)
Genetics
, vol.155
, pp. 945-959
-
-
Pritchard, J.K.1
Stephens, M.2
Donnelly, P.3
-
31
-
-
33746512512
-
Principal components analysis corrects for stratification in genome-wide association studies
-
Price AL, Patterson NJ, Plenge RM, Weinblatt ME, Shadick NA, Reich D. Principal components analysis corrects for stratification in genome-wide association studies. Nat Genet 2006; 38: 904-909.
-
(2006)
Nat Genet
, vol.38
, pp. 904-909
-
-
Price, A.L.1
Patterson, N.J.2
Plenge, R.M.3
Weinblatt, M.E.4
Shadick, N.A.5
Reich, D.6
-
32
-
-
34548292504
-
PLINK: A tool set for whole-genome association and population-based linkage analyses
-
Purcell S, Neale B, Todd-Brown K, Thomas L, Ferreira MA, Bender D et al. PLINK: A tool set for whole-genome association and population-based linkage analyses. Am J Hum Genet 2007; 81: 559-575.
-
(2007)
Am J Hum Genet
, vol.81
, pp. 559-575
-
-
Purcell, S.1
Neale, B.2
Todd-Brown, K.3
Thomas, L.4
Ferreira, M.A.5
Bender, D.6
-
33
-
-
33744528341
-
Pharmacovigilance in a genomic era
-
Farahani P, Levine M. Pharmacovigilance in a genomic era. Pharmacogenomics J 2006; 6: 158-161.
-
(2006)
Pharmacogenomics J
, vol.6
, pp. 158-161
-
-
Farahani, P.1
Levine, M.2
-
34
-
-
0035934070
-
Risk of cardiovascular events associated with selective COX-2 inhibitors
-
Mukherjee D, Nissen SE, Topol EJ. Risk of cardiovascular events associated with selective COX-2 inhibitors. JAMA 2001; 286: 954-959.
-
(2001)
JAMA
, vol.286
, pp. 954-959
-
-
Mukherjee, D.1
Nissen, S.E.2
Topol, E.J.3
-
35
-
-
33748787405
-
Case-only analysis of treatment-covariate interactions in clinical trials
-
Vittinghoff E, Bauer DC. Case-only analysis of treatment-covariate interactions in clinical trials. Biometrics 2006; 62: 769-776.
-
(2006)
Biometrics
, vol.62
, pp. 769-776
-
-
Vittinghoff, E.1
Bauer, D.C.2
-
36
-
-
19944429040
-
A single-nucleotide polymorphism tagging set for human drug metabolism and transport
-
Ahmadi KR, Weale ME, Xue ZY, Soranzo N, Yarnall DP, Briley JD et al. A single-nucleotide polymorphism tagging set for human drug metabolism and transport. Nat Genet 2005; 37: 84-89.
-
(2005)
Nat Genet
, vol.37
, pp. 84-89
-
-
Ahmadi, K.R.1
Weale, M.E.2
Xue, Z.Y.3
Soranzo, N.4
Yarnall, D.P.5
Briley, J.D.6
-
38
-
-
1842607847
-
-
R Development Core Team, R Foundation for Statistical Computing: Vienna, Austria
-
R Development Core Team. R: A Language and Environment for Statistical Computing. R Foundation for Statistical Computing: Vienna, Austria, 2003.
-
(2003)
R: A Language and Environment for Statistical Computing
-
-
-
40
-
-
84950435288
-
A Network Algorithm for performing Fisher's exact test in r x c contingency tables
-
Mehta CR, Patel NR. A Network Algorithm for performing Fisher's exact test in r x c contingency tables. J Acoust Soc Am 1983; 78: 427-434.
-
(1983)
J Acoust Soc Am
, vol.78
, pp. 427-434
-
-
Mehta, C.R.1
Patel, N.R.2
-
42
-
-
70449529019
-
Discrete sequential boundaries for clinical trials
-
Lan KKG, DeMets DL. Discrete sequential boundaries for clinical trials. Biometrika 1983; 70: 659-663.
-
(1983)
Biometrika
, vol.70
, pp. 659-663
-
-
Lan, K.K.G.1
DeMets, D.L.2
|