메뉴 건너뛰기




Volumn 7, Issue 8, 2011, Pages

Ku must load directly onto the chromosome end in order to mediate its telomeric functions

Author keywords

[No Author keywords available]

Indexed keywords

CELL PROTEIN; HETERODIMER; KU ANTIGEN; PROTEIN SIR4; PROTEIN TLC1; TELOMERASE; UNCLASSIFIED DRUG; DNA BINDING PROTEIN; HIGH AFFINITY DNA BINDING FACTOR, S CEREVISIAE; HIGH AFFINITY DNA-BINDING FACTOR, S CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEIN; SILENT INFORMATION REGULATOR PROTEIN; SIR4 PROTEIN, S CEREVISIAE;

EID: 80052323540     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1002233     Document Type: Article
Times cited : (32)

References (58)
  • 1
    • 70350020161 scopus 로고    scopus 로고
    • Conservation of telomere protein complexes: shuffling through evolution
    • Linger BR, Price CM, (2009) Conservation of telomere protein complexes: shuffling through evolution. Crit Rev Biochem Mol Biol 44: 434-446.
    • (2009) Crit Rev Biochem Mol Biol , vol.44 , pp. 434-446
    • Linger, B.R.1    Price, C.M.2
  • 2
    • 46249125488 scopus 로고    scopus 로고
    • How shelterin protects mammalian telomeres
    • Palm W, de Lange T, (2008) How shelterin protects mammalian telomeres. Annu Rev Genet 42: 301-334.
    • (2008) Annu Rev Genet , vol.42 , pp. 301-334
    • Palm, W.1    de Lange, T.2
  • 3
    • 33746425690 scopus 로고    scopus 로고
    • Telomere-related genome instability in cancer
    • De Lange T, (2005) Telomere-related genome instability in cancer. Cold Spring Harb Symp Quant Biol 70: 197-204.
    • (2005) Cold Spring Harb Symp Quant Biol , vol.70 , pp. 197-204
    • De Lange, T.1
  • 4
    • 0029963828 scopus 로고    scopus 로고
    • The crystal structure of the DNA-binding domain of yeast RAP1 in complex with telomeric DNA
    • Konig P, Giraldo R, Chapman L, Rhodes D, (1996) The crystal structure of the DNA-binding domain of yeast RAP1 in complex with telomeric DNA. Cell 85: 125-136.
    • (1996) Cell , vol.85 , pp. 125-136
    • Konig, P.1    Giraldo, R.2    Chapman, L.3    Rhodes, D.4
  • 5
    • 21444444520 scopus 로고    scopus 로고
    • How the human telomeric proteins TRF1 and TRF2 recognize telomeric DNA: a view from high-resolution crystal structures
    • Court R, Chapman L, Fairall L, Rhodes D, (2005) How the human telomeric proteins TRF1 and TRF2 recognize telomeric DNA: a view from high-resolution crystal structures. EMBO Rep 6: 39-45.
    • (2005) EMBO Rep , vol.6 , pp. 39-45
    • Court, R.1    Chapman, L.2    Fairall, L.3    Rhodes, D.4
  • 7
    • 0032431057 scopus 로고    scopus 로고
    • Crystal structure of the Oxytricha nova telomere end binding protein complexed with single strand DNA
    • Horvath MP, Schweiker VL, Bevilacqua JM, Ruggles JA, Schultz SC, (1998) Crystal structure of the Oxytricha nova telomere end binding protein complexed with single strand DNA. Cell 95: 963-974.
    • (1998) Cell , vol.95 , pp. 963-974
    • Horvath, M.P.1    Schweiker, V.L.2    Bevilacqua, J.M.3    Ruggles, J.A.4    Schultz, S.C.5
  • 8
    • 0029048189 scopus 로고
    • The carboxy termini of Sir4 and Rap1 affect Sir3 localization: evidence for a multicomponent complex required for yeast telomeric silencing
    • Cockell M, Palladino F, Laroche T, Kyrion G, Liu C, et al. (1995) The carboxy termini of Sir4 and Rap1 affect Sir3 localization: evidence for a multicomponent complex required for yeast telomeric silencing. J Cell Biol 129: 909-924.
    • (1995) J Cell Biol , vol.129 , pp. 909-924
    • Cockell, M.1    Palladino, F.2    Laroche, T.3    Kyrion, G.4    Liu, C.5
  • 9
    • 6944232071 scopus 로고    scopus 로고
    • TIN2 binds TRF1 and TRF2 simultaneously and stabilizes the TRF2 complex on telomeres
    • Ye JZ, Donigian JR, van Overbeek M, Loayza D, Luo Y, et al. (2004) TIN2 binds TRF1 and TRF2 simultaneously and stabilizes the TRF2 complex on telomeres. J Biol Chem 279: 47264-47271.
    • (2004) J Biol Chem , vol.279 , pp. 47264-47271
    • Ye, J.Z.1    Donigian, J.R.2    van Overbeek, M.3    Loayza, D.4    Luo, Y.5
  • 11
    • 12844265975 scopus 로고    scopus 로고
    • Structure of human POT1 bound to telomeric single-stranded DNA provides a model for chromosome end-protection
    • Lei M, Podell ER, Cech TR, (2004) Structure of human POT1 bound to telomeric single-stranded DNA provides a model for chromosome end-protection. Nat Struct Mol Biol 11: 1223-1229.
    • (2004) Nat Struct Mol Biol , vol.11 , pp. 1223-1229
    • Lei, M.1    Podell, E.R.2    Cech, T.R.3
  • 12
    • 3242680818 scopus 로고    scopus 로고
    • PTOP interacts with POT1 and regulates its localization to telomeres
    • Liu D, Safari A, O'Connor MS, Chan DW, Laegeler A, et al. (2004) PTOP interacts with POT1 and regulates its localization to telomeres. Nat Cell Biol 6: 673-680.
    • (2004) Nat Cell Biol , vol.6 , pp. 673-680
    • Liu, D.1    Safari, A.2    O'Connor, M.S.3    Chan, D.W.4    Laegeler, A.5
  • 13
    • 0032052815 scopus 로고    scopus 로고
    • Interaction of Ku protein and DNA-dependent protein kinase subunits with nucleic acids
    • Dynan WS, Yoo S, (1998) Interaction of Ku protein and DNA-dependent protein kinase subunits with nucleic acids. Nucleic Acids Res 26: 1551-1559.
    • (1998) Nucleic Acids Res , vol.26 , pp. 1551-1559
    • Dynan, W.S.1    Yoo, S.2
  • 14
    • 0035833552 scopus 로고    scopus 로고
    • Structure of the Ku heterodimer bound to DNA and its implications for double-strand break repair
    • Walker JR, Corpina RA, Goldberg J, (2001) Structure of the Ku heterodimer bound to DNA and its implications for double-strand break repair. Nature 412: 607-614.
    • (2001) Nature , vol.412 , pp. 607-614
    • Walker, J.R.1    Corpina, R.A.2    Goldberg, J.3
  • 15
    • 0032076127 scopus 로고    scopus 로고
    • Yeast Ku as a regulator of chromosomal DNA end structure
    • Gravel S, Larrivee M, Labrecque P, Wellinger RJ, (1998) Yeast Ku as a regulator of chromosomal DNA end structure. Science 280: 741-745.
    • (1998) Science , vol.280 , pp. 741-745
    • Gravel, S.1    Larrivee, M.2    Labrecque, P.3    Wellinger, R.J.4
  • 16
    • 67649743445 scopus 로고    scopus 로고
    • Sequential loading of Saccharomyces cerevisiae Ku and Cdc13p to telomeres
    • Wu TJ, Chiang YH, Lin YC, Tsai CR, Yu TY, et al. (2009) Sequential loading of Saccharomyces cerevisiae Ku and Cdc13p to telomeres. J Biol Chem 284: 12801-12808.
    • (2009) J Biol Chem , vol.284 , pp. 12801-12808
    • Wu, T.J.1    Chiang, Y.H.2    Lin, Y.C.3    Tsai, C.R.4    Yu, T.Y.5
  • 17
    • 16544390953 scopus 로고    scopus 로고
    • Cell cycle-dependent regulation of yeast telomerase by Ku
    • Fisher TS, Taggart AK, Zakian VA, (2004) Cell cycle-dependent regulation of yeast telomerase by Ku. Nat Struct Mol Biol 11: 1198-1205.
    • (2004) Nat Struct Mol Biol , vol.11 , pp. 1198-1205
    • Fisher, T.S.1    Taggart, A.K.2    Zakian, V.A.3
  • 19
    • 71149093724 scopus 로고    scopus 로고
    • How telomeres solve the end-protection problem
    • de Lange T, (2009) How telomeres solve the end-protection problem. Science 326: 948-952.
    • (2009) Science , vol.326 , pp. 948-952
    • de Lange, T.1
  • 20
    • 0347683485 scopus 로고    scopus 로고
    • Separation-of-function mutants of yeast Ku80 reveal a Yku80p-Sir4p interaction involved in telomeric silencing
    • Roy R, Meier B, McAinsh AD, Feldmann HM, Jackson SP, (2004) Separation-of-function mutants of yeast Ku80 reveal a Yku80p-Sir4p interaction involved in telomeric silencing. J Biol Chem 279: 86-94.
    • (2004) J Biol Chem , vol.279 , pp. 86-94
    • Roy, R.1    Meier, B.2    McAinsh, A.D.3    Feldmann, H.M.4    Jackson, S.P.5
  • 21
    • 3142616449 scopus 로고    scopus 로고
    • The human Rap1 protein complex and modulation of telomere length
    • O'Connor MS, Safari A, Liu D, Qin J, Songyang Z, (2004) The human Rap1 protein complex and modulation of telomere length. J Biol Chem 279: 28585-28591.
    • (2004) J Biol Chem , vol.279 , pp. 28585-28591
    • O'Connor, M.S.1    Safari, A.2    Liu, D.3    Qin, J.4    Songyang, Z.5
  • 22
    • 0034669104 scopus 로고    scopus 로고
    • Ku acts in a unique way at the mammalian telomere to prevent end joining
    • Hsu HL, Gilley D, Galande SA, Hande MP, Allen B, et al. (2000) Ku acts in a unique way at the mammalian telomere to prevent end joining. Genes Dev 14: 2807-2812.
    • (2000) Genes Dev , vol.14 , pp. 2807-2812
    • Hsu, H.L.1    Gilley, D.2    Galande, S.A.3    Hande, M.P.4    Allen, B.5
  • 24
    • 0141525391 scopus 로고    scopus 로고
    • Ku interacts with telomerase RNA to promote telomere addition at native and broken chromosome ends
    • Stellwagen AE, Haimberger ZW, Veatch JR, Gottschling DE, (2003) Ku interacts with telomerase RNA to promote telomere addition at native and broken chromosome ends. Genes Dev 17: 2384-2395.
    • (2003) Genes Dev , vol.17 , pp. 2384-2395
    • Stellwagen, A.E.1    Haimberger, Z.W.2    Veatch, J.R.3    Gottschling, D.E.4
  • 25
    • 0033612287 scopus 로고    scopus 로고
    • Relocalization of telomeric Ku and SIR proteins in response to DNA strand breaks in yeast
    • Martin SG, Laroche T, Suka N, Grunstein M, Gasser SM, (1999) Relocalization of telomeric Ku and SIR proteins in response to DNA strand breaks in yeast. Cell 97: 621-633.
    • (1999) Cell , vol.97 , pp. 621-633
    • Martin, S.G.1    Laroche, T.2    Suka, N.3    Grunstein, M.4    Gasser, S.M.5
  • 26
    • 0036682516 scopus 로고    scopus 로고
    • ExoI-dependent single-stranded DNA at telomeres activates subsets of DNA damage and spindle checkpoint pathways in budding yeast yku70Δ mutants
    • Maringele L, Lydall D, (2002) ExoI-dependent single-stranded DNA at telomeres activates subsets of DNA damage and spindle checkpoint pathways in budding yeast yku70Δ mutants. Genes Dev 16: 1919-1933.
    • (2002) Genes Dev , vol.16 , pp. 1919-1933
    • Maringele, L.1    Lydall, D.2
  • 27
    • 2442520305 scopus 로고    scopus 로고
    • EXO1 contributes to telomere maintenance in both telomerase-proficient and telomerase-deficient Saccharomyces cerevisiae
    • Bertuch AA, Lundblad V, (2004) EXO1 contributes to telomere maintenance in both telomerase-proficient and telomerase-deficient Saccharomyces cerevisiae. Genetics 166: 1651-1659.
    • (2004) Genetics , vol.166 , pp. 1651-1659
    • Bertuch, A.A.1    Lundblad, V.2
  • 28
    • 51549095956 scopus 로고    scopus 로고
    • Sgs1 helicase and two nucleases Dna2 and Exo1 resect DNA double-strand break ends
    • Zhu Z, Chung WH, Shim EY, Lee SE, Ira G, (2008) Sgs1 helicase and two nucleases Dna2 and Exo1 resect DNA double-strand break ends. Cell 134: 981-994.
    • (2008) Cell , vol.134 , pp. 981-994
    • Zhu, Z.1    Chung, W.H.2    Shim, E.Y.3    Lee, S.E.4    Ira, G.5
  • 29
    • 53649104599 scopus 로고    scopus 로고
    • Sae2, Exo1 and Sgs1 collaborate in DNA double-strand break processing
    • Mimitou EP, Symington LS, (2008) Sae2, Exo1 and Sgs1 collaborate in DNA double-strand break processing. Nature 455: 770-774.
    • (2008) Nature , vol.455 , pp. 770-774
    • Mimitou, E.P.1    Symington, L.S.2
  • 30
    • 0032536861 scopus 로고    scopus 로고
    • Components of the Ku-dependent non-homologous end-joining pathway are involved in telomeric length maintenance and telomeric silencing
    • Boulton SJ, Jackson SP, (1998) Components of the Ku-dependent non-homologous end-joining pathway are involved in telomeric length maintenance and telomeric silencing. EMBO J 17: 1819-1828.
    • (1998) EMBO J , vol.17 , pp. 1819-1828
    • Boulton, S.J.1    Jackson, S.P.2
  • 31
    • 0025201982 scopus 로고
    • Position effect at S. cerevisiae telomeres: reversible repression of Pol II transcription
    • Gottschling DE, Aparicio OM, Billington BL, Zakian VA, (1990) Position effect at S. cerevisiae telomeres: reversible repression of Pol II transcription. Cell 63: 751-762.
    • (1990) Cell , vol.63 , pp. 751-762
    • Gottschling, D.E.1    Aparicio, O.M.2    Billington, B.L.3    Zakian, V.A.4
  • 32
    • 0033533699 scopus 로고    scopus 로고
    • Yeast Ku protein plays a direct role in telomeric silencing and counteracts inhibition by rif proteins
    • Mishra K, Shore D, (1999) Yeast Ku protein plays a direct role in telomeric silencing and counteracts inhibition by rif proteins. Curr Biol 9: 1123-1126.
    • (1999) Curr Biol , vol.9 , pp. 1123-1126
    • Mishra, K.1    Shore, D.2
  • 33
    • 0037097940 scopus 로고    scopus 로고
    • Rap1-Sir4 binding independent of other Sir, yKu, or histone interactions initiates the assembly of telomeric heterochromatin in yeast
    • Luo K, Vega-Palas MA, Grunstein M, (2002) Rap1-Sir4 binding independent of other Sir, yKu, or histone interactions initiates the assembly of telomeric heterochromatin in yeast. Genes Dev 16: 1528-1539.
    • (2002) Genes Dev , vol.16 , pp. 1528-1539
    • Luo, K.1    Vega-Palas, M.A.2    Grunstein, M.3
  • 34
    • 0141868298 scopus 로고    scopus 로고
    • The Ku heterodimer performs separable activities at double strand breaks and chromosome termini
    • Bertuch AA, Lundblad V, (2003) The Ku heterodimer performs separable activities at double strand breaks and chromosome termini. Mol Cell Biol 23: 8202-8215.
    • (2003) Mol Cell Biol , vol.23 , pp. 8202-8215
    • Bertuch, A.A.1    Lundblad, V.2
  • 35
    • 0037164718 scopus 로고    scopus 로고
    • Live imaging of telomeres: yKu and Sir proteins define redundant telomere-anchoring pathways in yeast
    • Hediger F, Neumann FR, Van Houwe G, Dubrana K, Gasser SM, (2002) Live imaging of telomeres: yKu and Sir proteins define redundant telomere-anchoring pathways in yeast. Curr Biol 12: 2076-2089.
    • (2002) Curr Biol , vol.12 , pp. 2076-2089
    • Hediger, F.1    Neumann, F.R.2    Van Houwe, G.3    Dubrana, K.4    Gasser, S.M.5
  • 36
    • 1942503933 scopus 로고    scopus 로고
    • Separation of silencing from perinuclear anchoring functions in yeast Ku80, Sir4 and Esc1 proteins
    • Taddei A, Hediger F, Neumann FR, Bauer C, Gasser SM, (2004) Separation of silencing from perinuclear anchoring functions in yeast Ku80, Sir4 and Esc1 proteins. EMBO J 23: 1301-1312.
    • (2004) EMBO J , vol.23 , pp. 1301-1312
    • Taddei, A.1    Hediger, F.2    Neumann, F.R.3    Bauer, C.4    Gasser, S.M.5
  • 37
    • 65249165924 scopus 로고    scopus 로고
    • Yeast telomerase and the SUN domain protein Mps3 anchor telomeres and repress subtelomeric recombination
    • Schober H, Ferreira H, Kalck V, Gehlen LR, Gasser SM, (2009) Yeast telomerase and the SUN domain protein Mps3 anchor telomeres and repress subtelomeric recombination. Genes Dev 23: 928-938.
    • (2009) Genes Dev , vol.23 , pp. 928-938
    • Schober, H.1    Ferreira, H.2    Kalck, V.3    Gehlen, L.R.4    Gasser, S.M.5
  • 38
    • 0034885665 scopus 로고    scopus 로고
    • Localization of yeast telomeres to the nuclear periphery is separable from transcriptional repression and telomere stability functions
    • Tham WH, Wyithe JS, Ferrigno PK, Silver PA, Zakian VA, (2001) Localization of yeast telomeres to the nuclear periphery is separable from transcriptional repression and telomere stability functions. Mol Cell 8: 189-199.
    • (2001) Mol Cell , vol.8 , pp. 189-199
    • Tham, W.H.1    Wyithe, J.S.2    Ferrigno, P.K.3    Silver, P.A.4    Zakian, V.A.5
  • 39
    • 0034637443 scopus 로고    scopus 로고
    • A short C-terminal domain of Yku70p is essential for telomere maintenance
    • Driller L, Wellinger RJ, Larrivee M, Kremmer E, Jaklin S, et al. (2000) A short C-terminal domain of Yku70p is essential for telomere maintenance. J Biol Chem 275: 24921-24927.
    • (2000) J Biol Chem , vol.275 , pp. 24921-24927
    • Driller, L.1    Wellinger, R.J.2    Larrivee, M.3    Kremmer, E.4    Jaklin, S.5
  • 40
    • 34247194102 scopus 로고    scopus 로고
    • Distinct faces of the Ku heterodimer mediate DNA repair and telomeric functions
    • Ribes-Zamora A, Mihalek I, Lichtarge O, Bertuch AA, (2007) Distinct faces of the Ku heterodimer mediate DNA repair and telomeric functions. Nat Struct Mol Biol 14: 301-307.
    • (2007) Nat Struct Mol Biol , vol.14 , pp. 301-307
    • Ribes-Zamora, A.1    Mihalek, I.2    Lichtarge, O.3    Bertuch, A.A.4
  • 41
    • 0029954821 scopus 로고    scopus 로고
    • Mutations in two Ku homologs define a DNA end-joining repair pathway in Saccharomyces cerevisiae
    • Milne GT, Jin S, Shannon KB, Weaver DT, (1996) Mutations in two Ku homologs define a DNA end-joining repair pathway in Saccharomyces cerevisiae. Mol Cell Biol 16: 4189-4198.
    • (1996) Mol Cell Biol , vol.16 , pp. 4189-4198
    • Milne, G.T.1    Jin, S.2    Shannon, K.B.3    Weaver, D.T.4
  • 42
    • 0032554797 scopus 로고    scopus 로고
    • Telomere maintenance is dependent on activities required for end repair of double-strand breaks
    • Nugent CI, Bosco G, Ross LO, Evans SK, Salinger AP, et al. (1998) Telomere maintenance is dependent on activities required for end repair of double-strand breaks. Curr Biol 8: 657-660.
    • (1998) Curr Biol , vol.8 , pp. 657-660
    • Nugent, C.I.1    Bosco, G.2    Ross, L.O.3    Evans, S.K.4    Salinger, A.P.5
  • 43
    • 0032554793 scopus 로고    scopus 로고
    • Mutation of yeast Ku genes disrupts the subnuclear organization of telomeres
    • Laroche T, Martin SG, Gotta M, Gorham HC, Pryde FE, et al. (1998) Mutation of yeast Ku genes disrupts the subnuclear organization of telomeres. Curr Biol 8: 653-656.
    • (1998) Curr Biol , vol.8 , pp. 653-656
    • Laroche, T.1    Martin, S.G.2    Gotta, M.3    Gorham, H.C.4    Pryde, F.E.5
  • 44
    • 0033565609 scopus 로고    scopus 로고
    • Role of yeast SIR genes and mating type in directing DNA double-strand breaks to homologous and non-homologous repair paths
    • Lee SE, Paques F, Sylvan J, Haber JE, (1999) Role of yeast SIR genes and mating type in directing DNA double-strand breaks to homologous and non-homologous repair paths. Curr Biol 9: 767-770.
    • (1999) Curr Biol , vol.9 , pp. 767-770
    • Lee, S.E.1    Paques, F.2    Sylvan, J.3    Haber, J.E.4
  • 45
    • 77953245442 scopus 로고    scopus 로고
    • Shelterin-like proteins and Yku inhibit nucleolytic processing of Saccharomyces cerevisiae telomeres
    • doi: 10.1371/journal.pgen.1000966
    • Bonetti D, Clerici M, Anbalagan S, Martina M, Lucchini G, et al. (2010) Shelterin-like proteins and Yku inhibit nucleolytic processing of Saccharomyces cerevisiae telomeres. PLoS Genet 6: e1000966 doi:10.1371/journal.pgen.1000966.
    • (2010) PLoS Genet , vol.6
    • Bonetti, D.1    Clerici, M.2    Anbalagan, S.3    Martina, M.4    Lucchini, G.5
  • 46
    • 33749059184 scopus 로고    scopus 로고
    • DNA degradation at unprotected telomeres in yeast is regulated by the CDK1 (Cdc28/Clb) cell-cycle kinase
    • Vodenicharov MD, Wellinger RJ, (2006) DNA degradation at unprotected telomeres in yeast is regulated by the CDK1 (Cdc28/Clb) cell-cycle kinase. Mol Cell 24: 127-137.
    • (2006) Mol Cell , vol.24 , pp. 127-137
    • Vodenicharov, M.D.1    Wellinger, R.J.2
  • 47
    • 70649090280 scopus 로고    scopus 로고
    • The association of yKu with subtelomeric core X sequences prevents recombination involving telomeric sequences
    • Marvin ME, Becker MM, Noel P, Hardy S, Bertuch AA, et al. (2009) The association of yKu with subtelomeric core X sequences prevents recombination involving telomeric sequences. Genetics 183: 453-467, 451SI-413SI.
    • (2009) Genetics , vol.183
    • Marvin, M.E.1    Becker, M.M.2    Noel, P.3    Hardy, S.4    Bertuch, A.A.5
  • 48
    • 70649099209 scopus 로고    scopus 로고
    • In Saccharomyces cerevisiae, yKu and subtelomeric core X sequences repress homologous recombination near telomeres as part of the same pathway
    • Marvin ME, Griffin CD, Eyre DE, Barton DB, Louis EJ, (2009) In Saccharomyces cerevisiae, yKu and subtelomeric core X sequences repress homologous recombination near telomeres as part of the same pathway. Genetics 183: 441-451, 441SI-412SI.
    • (2009) Genetics , vol.183
    • Marvin, M.E.1    Griffin, C.D.2    Eyre, D.E.3    Barton, D.B.4    Louis, E.J.5
  • 49
    • 0031027431 scopus 로고    scopus 로고
    • SIR2 and SIR4 interactions differ in core and extended telomeric heterochromatin in yeast
    • Strahl-Bolsinger S, Hecht A, Luo K, Grunstein M, (1997) SIR2 and SIR4 interactions differ in core and extended telomeric heterochromatin in yeast. Genes Dev 11: 83-93.
    • (1997) Genes Dev , vol.11 , pp. 83-93
    • Strahl-Bolsinger, S.1    Hecht, A.2    Luo, K.3    Grunstein, M.4
  • 50
    • 0033522444 scopus 로고    scopus 로고
    • Limitations of silencing at native yeast telomeres
    • Pryde FE, Louis EJ, (1999) Limitations of silencing at native yeast telomeres. EMBO J 18: 2538-2550.
    • (1999) EMBO J , vol.18 , pp. 2538-2550
    • Pryde, F.E.1    Louis, E.J.2
  • 51
    • 1542358186 scopus 로고    scopus 로고
    • Multiple pathways for telomere tethering: functional implications of subnuclear position for heterochromatin formation
    • Taddei A, Gasser SM, (2004) Multiple pathways for telomere tethering: functional implications of subnuclear position for heterochromatin formation. Biochim Biophys Acta 1677: 120-128.
    • (2004) Biochim Biophys Acta , vol.1677 , pp. 120-128
    • Taddei, A.1    Gasser, S.M.2
  • 52
    • 33644530693 scopus 로고    scopus 로고
    • Subtelomeric factors antagonize telomere anchoring and Tel1-independent telomere length regulation
    • Hediger F, Berthiau AS, van Houwe G, Gilson E, Gasser SM, (2006) Subtelomeric factors antagonize telomere anchoring and Tel1-independent telomere length regulation. Embo J 25: 857-867.
    • (2006) Embo J , vol.25 , pp. 857-867
    • Hediger, F.1    Berthiau, A.S.2    van Houwe, G.3    Gilson, E.4    Gasser, S.M.5
  • 53
    • 68149110347 scopus 로고    scopus 로고
    • Ku86 represses lethal telomere deletion events in human somatic cells
    • Wang Y, Ghosh G, Hendrickson EA, (2009) Ku86 represses lethal telomere deletion events in human somatic cells. Proc Natl Acad Sci U S A 106: 12430-12435.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 12430-12435
    • Wang, Y.1    Ghosh, G.2    Hendrickson, E.A.3
  • 54
    • 58149094903 scopus 로고    scopus 로고
    • Cdk1-dependent phosphorylation of Cdc13 coordinates telomere elongation during cell-cycle progression
    • Li S, Makovets S, Matsuguchi T, Blethrow JD, Shokat KM, et al. (2009) Cdk1-dependent phosphorylation of Cdc13 coordinates telomere elongation during cell-cycle progression. Cell 136: 50-61.
    • (2009) Cell , vol.136 , pp. 50-61
    • Li, S.1    Makovets, S.2    Matsuguchi, T.3    Blethrow, J.D.4    Shokat, K.M.5
  • 55
    • 0036118479 scopus 로고    scopus 로고
    • Essential regions of Saccharomyces cerevisiae telomerase RNA: separate elements for Est1p and Est2p interaction
    • Livengood AJ, Zaug AJ, Cech TR, (2002) Essential regions of Saccharomyces cerevisiae telomerase RNA: separate elements for Est1p and Est2p interaction. Mol Cell Biol 22: 2366-2374.
    • (2002) Mol Cell Biol , vol.22 , pp. 2366-2374
    • Livengood, A.J.1    Zaug, A.J.2    Cech, T.R.3
  • 56
    • 8644261817 scopus 로고    scopus 로고
    • Chromatin immunoprecipitation for determining the association of proteins with specific genomic regions in vivo
    • In: Ausubel FM, Brent R, Kingston RE, Moore DD, Seidman JG et al, editors, Current Protocols in Molecular Biology: John Wiley & Sons, Inc
    • Aparicio OM, Geisberg JV, Sekinger E, Yang A, Moqtaderi Z, et al. (2005) Chromatin immunoprecipitation for determining the association of proteins with specific genomic regions in vivo. In: Ausubel FM, Brent R, Kingston RE, Moore DD, Seidman JG et al, editors. Current Protocols in Molecular Biology: John Wiley & Sons, Inc pp. 21.23.21-21.23.17.
    • (2005) , pp. 17-21
    • Aparicio, O.M.1    Geisberg, J.V.2    Sekinger, E.3    Yang, A.4    Moqtaderi, Z.5
  • 57
    • 33947137710 scopus 로고    scopus 로고
    • Dynamics of replication-independent histone turnover in budding yeast
    • Dion MF, Kaplan T, Kim M, Buratowski S, Friedman N, et al. (2007) Dynamics of replication-independent histone turnover in budding yeast. Science 315: 1405-1408.
    • (2007) Science , vol.315 , pp. 1405-1408
    • Dion, M.F.1    Kaplan, T.2    Kim, M.3    Buratowski, S.4    Friedman, N.5
  • 58
    • 0030455861 scopus 로고    scopus 로고
    • Senescence mutants of Saccharomyces cerevisiae with a defect in telomere replication identify three additional EST genes
    • Lendvay TS, Morris DK, Sah J, Balasubramanian B, Lundblad V, (1996) Senescence mutants of Saccharomyces cerevisiae with a defect in telomere replication identify three additional EST genes. Genetics 144: 1399-1412.
    • (1996) Genetics , vol.144 , pp. 1399-1412
    • Lendvay, T.S.1    Morris, D.K.2    Sah, J.3    Balasubramanian, B.4    Lundblad, V.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.