-
1
-
-
0037452605
-
Loading of the human 9-1-1 checkpoint complex onto DNA by the checkpoint clamp loader hRad17-replication factor C complex in vitro
-
Bermudez VP, Lindsey-Boltz LA, Cesare AJ, Maniwa Y, Griffith JD, Hurwitz J, Sancar A. Loading of the human 9-1-1 checkpoint complex onto DNA by the checkpoint clamp loader hRad17-replication factor C complex in vitro. Proc. Natl Acad. Sci. USA 2003, 100:1633-1638.
-
(2003)
Proc. Natl Acad. Sci. USA
, vol.100
, pp. 1633-1638
-
-
Bermudez, V.P.1
Lindsey-Boltz, L.A.2
Cesare, A.J.3
Maniwa, Y.4
Griffith, J.D.5
Hurwitz, J.6
Sancar, A.7
-
2
-
-
44849128194
-
How ATR turns on: TopBP1 goes on ATRIP with ATR
-
Burrows AE, Elledge SJ. How ATR turns on: TopBP1 goes on ATRIP with ATR. Genes Dev. 2008, 22:1416-1421.
-
(2008)
Genes Dev.
, vol.22
, pp. 1416-1421
-
-
Burrows, A.E.1
Elledge, S.J.2
-
3
-
-
18244371925
-
Functional uncoupling of MCM helicase and DNA polymerase activities activates the ATR-dependent checkpoint
-
Byun TS, Pacek M, Yee MC, Walter JC, Cimprich KA. Functional uncoupling of MCM helicase and DNA polymerase activities activates the ATR-dependent checkpoint. Genes Dev. 2005, 19:1040-1052.
-
(2005)
Genes Dev.
, vol.19
, pp. 1040-1052
-
-
Byun, T.S.1
Pacek, M.2
Yee, M.C.3
Walter, J.C.4
Cimprich, K.A.5
-
4
-
-
48649100438
-
Phospho-dependent interactions between NBS1 and MDC1 mediate chromatin retention of the MRN complex at sites of DNA damage
-
Chapman JR, Jackson SP. Phospho-dependent interactions between NBS1 and MDC1 mediate chromatin retention of the MRN complex at sites of DNA damage. EMBO Rep. 2008, 9:795-801.
-
(2008)
EMBO Rep.
, vol.9
, pp. 795-801
-
-
Chapman, J.R.1
Jackson, S.P.2
-
5
-
-
33746849859
-
CDC7 kinase phosphorylates serine residues adjacent to acidic amino acids in the minichromosome maintenance 2 protein
-
Cho WH, Lee YJ, Kong SI, Hurwitz J, Lee JK. CDC7 kinase phosphorylates serine residues adjacent to acidic amino acids in the minichromosome maintenance 2 protein. Proc. Natl Acad. Sci. USA 2006, 103:11521-11526.
-
(2006)
Proc. Natl Acad. Sci. USA
, vol.103
, pp. 11521-11526
-
-
Cho, W.H.1
Lee, Y.J.2
Kong, S.I.3
Hurwitz, J.4
Lee, J.K.5
-
6
-
-
47749141560
-
ATR: an essential regulator of genome integrity
-
Cimprich KA, Cortez D. ATR: an essential regulator of genome integrity. Nat. Rev. Mol. Cell Biol. 2008, 9:616-627.
-
(2008)
Nat. Rev. Mol. Cell Biol.
, vol.9
, pp. 616-627
-
-
Cimprich, K.A.1
Cortez, D.2
-
7
-
-
0035941021
-
ATR and ATRIP: partners in checkpoint signaling
-
Cortez D, Guntuku S, Qin J, Elledge SJ. ATR and ATRIP: partners in checkpoint signaling. Science 2001, 294:1713-1716.
-
(2001)
Science
, vol.294
, pp. 1713-1716
-
-
Cortez, D.1
Guntuku, S.2
Qin, J.3
Elledge, S.J.4
-
8
-
-
34250705797
-
The Rad9-Hus1-Rad1 (9-1-1) clamp activates checkpoint signaling via TopBP1
-
Delacroix S, Wagner JM, Kobayashi M, Yamamoto K, Karnitz LM. The Rad9-Hus1-Rad1 (9-1-1) clamp activates checkpoint signaling via TopBP1. Genes Dev. 2007, 21:1472-1477.
-
(2007)
Genes Dev.
, vol.21
, pp. 1472-1477
-
-
Delacroix, S.1
Wagner, J.M.2
Kobayashi, M.3
Yamamoto, K.4
Karnitz, L.M.5
-
9
-
-
67649111979
-
Crystal structure of the human Rad9-Rad1-Hus1 DNA damage checkpoint complex - implications for clamp loading and regulation
-
Dore AS, Kilkenny M, Rzechorzek NJ, Pearl LH. Crystal structure of the human Rad9-Rad1-Hus1 DNA damage checkpoint complex - implications for clamp loading and regulation. Mol. Cell 2009, 34:735-745.
-
(2009)
Mol. Cell
, vol.34
, pp. 735-745
-
-
Dore, A.S.1
Kilkenny, M.2
Rzechorzek, N.J.3
Pearl, L.H.4
-
10
-
-
0042941728
-
HRad9 rapidly binds DNA containing double-strand breaks and is required for damage-dependent topoisomerase II[β] binding protein 1 focus formation
-
Greer DA, Besley BD, Kennedy KB, Davey S. hRad9 rapidly binds DNA containing double-strand breaks and is required for damage-dependent topoisomerase II[β] binding protein 1 focus formation. Cancer Res. 2003, 63:4829-4835.
-
(2003)
Cancer Res.
, vol.63
, pp. 4829-4835
-
-
Greer, D.A.1
Besley, B.D.2
Kennedy, K.B.3
Davey, S.4
-
11
-
-
0037013319
-
Structures of the human Rad17-replication factor C and checkpoint Rad 9-1-1 complexes visualized by glycerol spray/low voltage microscopy
-
Griffith JD, Lindsey-Boltz LA, Sancar A. Structures of the human Rad17-replication factor C and checkpoint Rad 9-1-1 complexes visualized by glycerol spray/low voltage microscopy. J. Biol. Chem. 2002, 277:15233-15236.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 15233-15236
-
-
Griffith, J.D.1
Lindsey-Boltz, L.A.2
Sancar, A.3
-
12
-
-
0030740541
-
The carboxy terminus of p53 mimics the polylysine effect of protein kinase CK2-catalyzed MDM2 phosphorylation
-
Guerra B, Götz C, Wagner P, Montenarh M, Issinger OG. The carboxy terminus of p53 mimics the polylysine effect of protein kinase CK2-catalyzed MDM2 phosphorylation. Oncogene 1997, 14:2683-2688.
-
(1997)
Oncogene
, vol.14
, pp. 2683-2688
-
-
Guerra, B.1
Götz, C.2
Wagner, P.3
Montenarh, M.4
Issinger, O.G.5
-
13
-
-
0025758832
-
Association of casein kinase II with immunopurified p53
-
Herrmann CP, Kraiss S, Montenarh M. Association of casein kinase II with immunopurified p53. Oncogene 1991, 6:877-884.
-
(1991)
Oncogene
, vol.6
, pp. 877-884
-
-
Herrmann, C.P.1
Kraiss, S.2
Montenarh, M.3
-
14
-
-
0030978319
-
A highly water-soluble disulfonated tetrazolium salt as a chromogenic indicator for NADH as well as cell viability
-
Ishiyama M, Miyazono Y, Sasamoto K, Ohkura Y, Ueno K. A highly water-soluble disulfonated tetrazolium salt as a chromogenic indicator for NADH as well as cell viability. Talanta 1997, 44:1299-1305.
-
(1997)
Talanta
, vol.44
, pp. 1299-1305
-
-
Ishiyama, M.1
Miyazono, Y.2
Sasamoto, K.3
Ohkura, Y.4
Ueno, K.5
-
15
-
-
33644757806
-
TopBP1 activates the ATR-ATRIP complex
-
Kumagai A, Lee J, Yoo HY, Dunphy WG. TopBP1 activates the ATR-ATRIP complex. Cell 2006, 124:943-955.
-
(2006)
Cell
, vol.124
, pp. 943-955
-
-
Kumagai, A.1
Lee, J.2
Yoo, H.Y.3
Dunphy, W.G.4
-
16
-
-
34948889415
-
The Rad9-Hus1-Rad1 checkpoint clamp regulates interaction of TopBP1 with ATR
-
Lee J, Kumagai A, Dunphy WG. The Rad9-Hus1-Rad1 checkpoint clamp regulates interaction of TopBP1 with ATR. J. Biol. Chem. 2007, 282:28036-28044.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 28036-28044
-
-
Lee, J.1
Kumagai, A.2
Dunphy, W.G.3
-
17
-
-
33644999937
-
Rad9, an evolutionarily conserved gene with multiple functions for preserving genomic integrity
-
Lieberman HB. Rad9, an evolutionarily conserved gene with multiple functions for preserving genomic integrity. J. Cell. Biochem. 2006, 97:690-697.
-
(2006)
J. Cell. Biochem.
, vol.97
, pp. 690-697
-
-
Lieberman, H.B.1
-
18
-
-
11144355098
-
The protein kinase CK2 facilitates repair of chromosomal DNA single-strand breaks
-
Loizou JI, El-Khamisy SF, Zlatanou A, Moore DJ, Chan DW, Qin J, Sarno S, Meggio F, Pinna LA, Caldecott KW. The protein kinase CK2 facilitates repair of chromosomal DNA single-strand breaks. Cell 2004, 117:17-28.
-
(2004)
Cell
, vol.117
, pp. 17-28
-
-
Loizou, J.I.1
El-Khamisy, S.F.2
Zlatanou, A.3
Moore, D.J.4
Chan, D.W.5
Qin, J.6
Sarno, S.7
Meggio, F.8
Pinna, L.A.9
Caldecott, K.W.10
-
19
-
-
0242456024
-
BRCT domain-containing protein TopBP1 functions in DNA replication and damage response
-
Mäkiniemi M, Hillukkala T, Tuusa J, Reini K, Vaara M, Huang D, Pospiech H, Majuri I, Westerling T, Mäkelä TP, Syväoja JE. BRCT domain-containing protein TopBP1 functions in DNA replication and damage response. J. Biol. Chem. 2001, 276:30399-30406.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 30399-30406
-
-
Mäkiniemi, M.1
Hillukkala, T.2
Tuusa, J.3
Reini, K.4
Vaara, M.5
Huang, D.6
Pospiech, H.7
Majuri, I.8
Westerling, T.9
Mäkelä, T.P.10
Syväoja, J.E.11
-
20
-
-
0025143302
-
The p53 tumour suppressor protein is phosphorylated at serine 389 by casein kinase II
-
Meek DW, Simon S, Kikkawa U, Eckhart W. The p53 tumour suppressor protein is phosphorylated at serine 389 by casein kinase II. EMBO J. 1990, 9:3253-3260.
-
(1990)
EMBO J.
, vol.9
, pp. 3253-3260
-
-
Meek, D.W.1
Simon, S.2
Kikkawa, U.3
Eckhart, W.4
-
21
-
-
0037334895
-
One-thousand-and-one substrates of protein kinase CK2?
-
Meggio F, Pinna LA. One-thousand-and-one substrates of protein kinase CK2? FASEB J. 2003, 17:349-368.
-
(2003)
FASEB J.
, vol.17
, pp. 349-368
-
-
Meggio, F.1
Pinna, L.A.2
-
22
-
-
42449086413
-
Phosphorylation of SDT repeats in the MDC1 N terminus triggers retention of NBS1 at the DNA damage-modified chromatin
-
Melander F, Bekker-Jensen S, Falck J, Bartek J, Mailand N, Lukas J. Phosphorylation of SDT repeats in the MDC1 N terminus triggers retention of NBS1 at the DNA damage-modified chromatin. J. Cell Biol. 2008, 181:213-226.
-
(2008)
J. Cell Biol.
, vol.181
, pp. 213-226
-
-
Melander, F.1
Bekker-Jensen, S.2
Falck, J.3
Bartek, J.4
Mailand, N.5
Lukas, J.6
-
23
-
-
44849093460
-
TopBP1 activates ATR through ATRIP and a PIKK regulatory domain
-
Mordes DA, Glick GG, Zhao R, Cortez D. TopBP1 activates ATR through ATRIP and a PIKK regulatory domain. Genes Dev. 2008, 22:1478-1489.
-
(2008)
Genes Dev.
, vol.22
, pp. 1478-1489
-
-
Mordes, D.A.1
Glick, G.G.2
Zhao, R.3
Cortez, D.4
-
24
-
-
31444452984
-
ATRIP associates with replication protein A-coated ssDNA through multiple interactions
-
Namiki Y, Zou L. ATRIP associates with replication protein A-coated ssDNA through multiple interactions. Proc. Natl Acad. Sci. USA 2006, 103:580-585.
-
(2006)
Proc. Natl Acad. Sci. USA
, vol.103
, pp. 580-585
-
-
Namiki, Y.1
Zou, L.2
-
25
-
-
0037174948
-
A proteomics approach to identify proliferating cell nuclear antigen (PCNA)-binding proteins in human cell lysates. Identification of the human CHL12/RFCs2-5 complex as a novel PCNA-binding protein
-
Ohta S, Shiomi Y, Sugimoto K, Obuse C, Tsurimoto T. A proteomics approach to identify proliferating cell nuclear antigen (PCNA)-binding proteins in human cell lysates. Identification of the human CHL12/RFCs2-5 complex as a novel PCNA-binding protein. J. Biol. Chem. 2002, 277:40362-40367.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 40362-40367
-
-
Ohta, S.1
Shiomi, Y.2
Sugimoto, K.3
Obuse, C.4
Tsurimoto, T.5
-
26
-
-
33846334498
-
Tetrabromocinnamic acid (TBCA) and related compounds represent a new class of specific protein kinase CK2 inhibitors
-
Pagano MA, Poletto G, Di Maira G, Cozza G, Ruzzene M, Sarno S, Bain J, Elliott M, Moro S, Zagotto G, Meggio F, Pinna LA. Tetrabromocinnamic acid (TBCA) and related compounds represent a new class of specific protein kinase CK2 inhibitors. Chembiochem 2007, 8:129-139.
-
(2007)
Chembiochem
, vol.8
, pp. 129-139
-
-
Pagano, M.A.1
Poletto, G.2
Di Maira, G.3
Cozza, G.4
Ruzzene, M.5
Sarno, S.6
Bain, J.7
Elliott, M.8
Moro, S.9
Zagotto, G.10
Meggio, F.11
Pinna, L.A.12
-
27
-
-
3242887431
-
Dial 9-1-1 for DNA damage: the Rad9-Hus1-Rad1 (9-1-1) clamp complex
-
Parrilla-Castellar ER, Arlander SJ, Karnitz L. Dial 9-1-1 for DNA damage: the Rad9-Hus1-Rad1 (9-1-1) clamp complex. DNA Repair 2004, 3:1009-1014.
-
(2004)
DNA Repair
, vol.3
, pp. 1009-1014
-
-
Parrilla-Castellar, E.R.1
Arlander, S.J.2
Karnitz, L.3
-
28
-
-
0041589309
-
Phosphorylation of human Rad9 is required for genotoxin-activated checkpoint signaling
-
Roos-Mattjus P, Hopkins KM, Oestreich AJ, Vroman BT, Johnson KL, Naylor S, Lieberman HB, Karnitz LM. Phosphorylation of human Rad9 is required for genotoxin-activated checkpoint signaling. J. Biol. Chem. 2003, 278:24428-24437.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 24428-24437
-
-
Roos-Mattjus, P.1
Hopkins, K.M.2
Oestreich, A.J.3
Vroman, B.T.4
Johnson, K.L.5
Naylor, S.6
Lieberman, H.B.7
Karnitz, L.M.8
-
29
-
-
0036668474
-
Clamp and clamp loader structures of the human checkpoint protein complexes, Rad9-1-1 and Rad17-RFC
-
Shiomi Y, Shinozaki A, Nakada D, Sugimoto K, Usukura J, Obuse C, Tsurimoto T. Clamp and clamp loader structures of the human checkpoint protein complexes, Rad9-1-1 and Rad17-RFC. Genes Cells 2002, 7:861-868.
-
(2002)
Genes Cells
, vol.7
, pp. 861-868
-
-
Shiomi, Y.1
Shinozaki, A.2
Nakada, D.3
Sugimoto, K.4
Usukura, J.5
Obuse, C.6
Tsurimoto, T.7
-
30
-
-
67449103064
-
Crystal structure of the human Rad9-Hus1-Rad1 clamp
-
Sohn SY, Cho Y. Crystal structure of the human Rad9-Hus1-Rad1 clamp. J. Mol. Biol. 2009, 390:490-502.
-
(2009)
J. Mol. Biol.
, vol.390
, pp. 490-502
-
-
Sohn, S.Y.1
Cho, Y.2
-
31
-
-
42449115711
-
Constitutive phosphorylation of MDC1 physically links the MRE11-RAD50-NBS1 complex to damaged chromatin
-
Spycher C, Miller ES, Townsend K, Pavic L, Morrice NA, Janscak P, Stewart GS, Stucki M. Constitutive phosphorylation of MDC1 physically links the MRE11-RAD50-NBS1 complex to damaged chromatin. J. Cell Biol. 2008, 181:227-240.
-
(2008)
J. Cell Biol.
, vol.181
, pp. 227-240
-
-
Spycher, C.1
Miller, E.S.2
Townsend, K.3
Pavic, L.4
Morrice, N.A.5
Janscak, P.6
Stewart, G.S.7
Stucki, M.8
-
32
-
-
0037698170
-
A role for the phosphorylation of hRad9 in checkpoint signaling
-
St Onge RP, Besley BD, Pelley JL, Davey S. A role for the phosphorylation of hRad9 in checkpoint signaling. J. Biol. Chem. 2003, 278:26620-26628.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 26620-26628
-
-
St.Onge, R.P.1
Besley, B.D.2
Pelley, J.L.3
Davey, S.4
-
33
-
-
0034235463
-
Structure-based predictions of Rad1, Rad9, Hus1 and Rad17 participation in sliding clamp and clamp-loading complexes
-
Venclovas C, Thelen MP. Structure-based predictions of Rad1, Rad9, Hus1 and Rad17 participation in sliding clamp and clamp-loading complexes. Nucleic Acids Res. 2000, 28:2481-2493.
-
(2000)
Nucleic Acids Res.
, vol.28
, pp. 2481-2493
-
-
Venclovas, C.1
Thelen, M.P.2
-
34
-
-
49649089537
-
MDC1 regulates intra-S-phase checkpoint by targeting NBS1 to DNA double-strand breaks
-
Wu L, Luo K, Lou Z, Chen J. MDC1 regulates intra-S-phase checkpoint by targeting NBS1 to DNA double-strand breaks. Proc. Natl Acad. Sci. USA 2008, 105:11200-11205.
-
(2008)
Proc. Natl Acad. Sci. USA
, vol.105
, pp. 11200-11205
-
-
Wu, L.1
Luo, K.2
Lou, Z.3
Chen, J.4
-
35
-
-
68949137117
-
Structure and functional implications of the human Rad9-Hus1-Rad1 cell cycle checkpoint complex
-
Xu M, Bai L, Gong Y, Xie W, Hang H, Jiang T. Structure and functional implications of the human Rad9-Hus1-Rad1 cell cycle checkpoint complex. J. Biol. Chem. 2009, 284:20457-20461.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 20457-20461
-
-
Xu, M.1
Bai, L.2
Gong, Y.3
Xie, W.4
Hang, H.5
Jiang, T.6
-
36
-
-
0031574247
-
A DNA-topoisomerase-II-binding protein with eight repeating regions similar to DNA-repair enzymes and to a cell cycle regulator
-
Yamane K, Kawabata M, Tsuruo T. A DNA-topoisomerase-II-binding protein with eight repeating regions similar to DNA-repair enzymes and to a cell cycle regulator. Eur. J. Biochem. 1997, 250:794-799.
-
(1997)
Eur. J. Biochem.
, vol.250
, pp. 794-799
-
-
Yamane, K.1
Kawabata, M.2
Tsuruo, T.3
-
37
-
-
0037567268
-
Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes
-
Zou L, Elledge SJ. Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes. Science 2003, 300:1542-1548.
-
(2003)
Science
, vol.300
, pp. 1542-1548
-
-
Zou, L.1
Elledge, S.J.2
-
38
-
-
0345564858
-
Replication protein A-mediated recruitment and activation of Rad17 complexes
-
Zou L, Liu D, Elledge SJ. Replication protein A-mediated recruitment and activation of Rad17 complexes. Proc. Natl Acad. Sci. USA 2003, 100:13827-13832.
-
(2003)
Proc. Natl Acad. Sci. USA
, vol.100
, pp. 13827-13832
-
-
Zou, L.1
Liu, D.2
Elledge, S.J.3
|