Uncoupling of M1 muscarinic receptor/G-protein interaction by amyloid β1-42

Neuropharmacology

Volumn 67, Issue , 2013, Pages 272-283

  Janíčková, Helena ^a   Rudajev, Vladimír ^a   Zimčík, Pavel ^a   Jakubík, Jan ^a   Tanila, Heikki ^b,c   El Fakahany, Esam E ^d   Doležal, Vladimír ^a  

^a INSTITUTE OF PHYSIOLOGY   (Czech Republic)

^b UNIVERSITY OF EASTERN FINLAND   (Finland)

^c KUOPIO UNIVERSITY HOSPITAL   (Finland)

^d UNIVERSITY OF MINNESOTA   (United States)

Author keywords

Agonist binding; Amyloid 1 42; G proteins; Muscarinic receptors; Phosphatidylinositol breakdown

Indexed keywords

AMYLOID BETA PROTEIN[1-42]; CELL PROTEIN; GO PROTEIN; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; INHIBITORY GUANINE NUCLEOTIDE BINDING PROTEIN; MESSENGER RNA; MUSCARINIC M1 RECEPTOR; NUCLEOTIDE BINDING PROTEIN; PHOSPHATIDYLINOSITOL; STIMULATORY GUANINE NUCLEOTIDE BINDING PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; BINDING SITE; BIOACCUMULATION; BRAIN CORTEX; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; IN VITRO STUDY; MOLECULAR DYNAMICS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN BINDING; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; WILD TYPE;

AMYLOID BETA-PEPTIDES; ANIMALS; CELLS, CULTURED; CHO CELLS; CRICETINAE; CRICETULUS; FEMALE; HUMANS; MICE; MICE, TRANSGENIC; PEPTIDE FRAGMENTS; PROTEIN BINDING; RECEPTOR, MUSCARINIC M1; RECEPTORS, G-PROTEIN-COUPLED; UNCOUPLING AGENTS;

EID: 84873332558     PISSN: 00283908     EISSN: 18737064     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2012.11.014     Document Type: Article

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