Angiotensin II AT2 receptor oligomers mediate G-protein dysfunction in an animal model of Alzheimer disease

Journal of Biological Chemistry

Volumn 284, Issue 10, 2009, Pages 6554-6565

  AbdAlla, Said ^a   Lother, Heinz ^a   El Missiry, Ahmed ^b   Langer, Andreas ^c   Sergeev, Pavel ^c   El Faramawy, Yasser ^a   Quitterer, Ursula ^c,d  

^a LEIBNIZ INSTITUTE FOR EXPERIMENTAL VIROLOGY   (Germany)

^b AIN SHAMS UNIVERSITY   (Egypt)

^c UNIVERSITY OF ZURICH   (Switzerland)

^d NONE   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ALZHEIMER DISEASE; ANGIOTENSIN II; ANIMAL MODEL; COGNITIVE FUNCTIONS; CROSSLINKED; DOSE-DEPENDENT MANNER; G PROTEIN; MICRO-INJECTION; NEURODEGENERATION; PHOSPHOINOSITIDE; RNA INTERFERENCE; SIGNAL TRANSDUCTION MECHANISM; TRANSGENIC MICE; TRANSGLUTAMINASE; TWO-STEP PROCESS;

NUCLEIC ACIDS; OLIGOMERIZATION; PLANTS (BOTANY); RNA; SIGNAL TRANSDUCTION;

OLIGOMERS;

AMYLOID BETA PROTEIN; ANGIOTENSIN 2 RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; OLIGOMER; PROTEIN GLUTAMINE GAMMA GLUTAMYLTRANSFERASE; TAU PROTEIN;

ADULT; AGED; ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; CROSS LINKING; FEMALE; HIPPOCAMPUS; HUMAN; HUMAN TISSUE; MALE; MICROINJECTION; MOUSE; NERVE DEGENERATION; NEUROPATHOLOGY; NONHUMAN; OLIGOMERIZATION; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN DEFECT; PROTEIN PHOSPHORYLATION; RNA INTERFERENCE; SIGNAL TRANSDUCTION; STEREOTACTIC TREATMENT; TRANSGENIC MOUSE; ANIMAL; DISEASE MODEL; GENETICS; METABOLISM; MIDDLE AGED;

ANIMALIA; MUS; MUS MUSCULUS;

AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; ANIMALS; DISEASE MODELS, ANIMAL; FEMALE; GTP-BINDING PROTEIN ALPHA SUBUNITS, GQ-G11; HIPPOCAMPUS; HUMANS; MALE; MICE; MICE, TRANSGENIC; MIDDLE AGED; RECEPTOR, ANGIOTENSIN, TYPE 2; SIGNAL TRANSDUCTION;

EID: 65249120870     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M807746200     Document Type: Article

References (41)

1. Price, J. L., and Morris, J. C. (1999) Ann. Neurol. 45, 358-368
2. Gomez-Isla, T., Hollister, R., West, H., Mui, S., Growdon, J. H., Petersen, R. C., Parisi, J. E., and Hyman, B. T. (1997) Ann. Neurol. 41, 17-24
3. Price, J. L., Ko, A. I., Wade, M. J., Tsou, S. K., McKeel, D. W., and Morris, J. C. (2001) Arch. Neurol. 58, 1395-1402
4. Ferrari-DiLeo, G., and Flynn, D. D. (1993) Life Sci. 53, PL439-PL444
5. Fowler, C. J., Cowburn, R. F., Garlind, A., Winblad, B., and O'Neill, C. (1995) Mol. Cell Biochem. 149, 287-292
6. Greenwood, A. F., Powers, R. E., and Jope, R. S. (1995) Neuroscience 69, 125-138
7. Jope, R. S., Song, L., Li, X., and Powers, R. (1994) Neurobiol. Aging 15, 221-226
8. Tsang, S. W., Lai, M. K., Kirvell, S., Francis, P. T., Esiri, M. M., Hope, T., Chen, C. P., and Wong, P. T. (2006) Neurobiol. Aging 27, 1216-1223
9. Miura, M., Watanabe, M., Offermanns, S., Simon, M. I., and Kano, M. (2002) J. Neurosci. 22, 8379-8390
10. Wettschureck, N., van der Stelt, M., Tsubokawa, H., Krestel, H., Moers, A., Petrosino, S., Schütz, G., Di Marzo, V., and Offermanns, S. (2006) Mol. Cell. Biol. 26, 5888-5894
11. AbdAlla, S., Lother, H., Abdel-tawab, A. M., and Quitterer, U. (2001) J. Biol. Chem. 276, 39721-39726
12. Ichiki, T., Labosky, P. A., Shiota, C., Okuyama, S., Imagawa, Y., Fogo, A., Niimura, F., Ichikawa, I., Hogan, B. L., and Inagami, T. (1995) Nature 377, 748-750
13. Shenoy, U. V., Richards, E. M., Huang, X.-C., and Sumners, C. (1999) Endocrinology 140, 500-509
14. Vervoort, V. S., Beachem, M. A., Edwards, P. S., Ladd, S., Miller, K. E., de Mollerat, X., Clarkson, K., DuPont, B., Schwartz, C. E., Stevenson, R. E., Boyd, E., and Srivastava, A. K. (2002) Science 296, 2401-2403
15. AbdAlla, S., Lother, H., Langer, A., el Faramawy, Y., and Quitterer, U. (2004) Cell 119, 343-354
16. AbdAlla, S., Lother, H., and Quitterer, U. (2000) Nature 407, 94-98
17. AbdAlla, S., Lother, H., el Massiery, A., and Quitterer, U. (2001) Nat. Med. 7, 1003-1009
18. Hsiao, K., Chapman, P., Nilsen, S., Eckman, C., Harigaya, Y., Younkin, S., Yang, F., and Cole, G. (1996) Science 274, 99-102
19. Dickstein, D. L., Biron, K. E., Ujiie, M., Pfeifer, C. G., Jeffries, A. R., and Jefferies, W. A. (2006) FASEB J. 20, 426-433
20. Singer, O., Marr, R. A., Rockenstein, E., Crews, L., Coufal, N. G., Gage, F. H., Verma, I. M., and Masliah, E. (2005) Nat. Neurosci. 8, 1343-1349
21. Walsh, D. M., Klyubin, I., Fadeeva, J. V., Cullen, W. K., Anwyl, R., Wolfe, M. S., Rowan, M. J., and Selkoe, D. J. (2002) Nature 416, 535-539
22. Kowall, N. W., Beal, M. F., Busciglio, J., Duffy, L. K., and Yankner, B. A. (1991) Proc. Natl. Acad. Sci. U. S. A. 88, 7247-7251
23. Monleon, S., D'Aguila, P., Parra, A., Simon, V. M., Brain, P. F., and Willner, P. (1995) Psychopharmacology 117, 453-457
24. Morris, R. G. M., Garrud, P., Rawlins, J. N. P., and O'Keefe, J. (1982) Nature 297, 681-683
25. King, D. L., and Arendash, G. W. (2002) Physiol. Behav. 75, 627-642
26. Chen, S., Lin, F., Xu, M., Hwa, J., and Graham, R. M. (2000) EMBO J. 19, 4265-4271
27. Irizarry, M. C., McNamara, M., Fedorchak, K., Hsiao, K., and Hyman, B. T. (1997) J. Neuropathol. Exp. Neurol. 56, 965-973
28. Jeong, Y. H., Park, C. H., Yoo, J., Shin, K. Y., Ahn, S. M., Kim, H. S., Lee, S. H., Emson, P. C., and Suh, Y. H. (2006) FASEB J. 20, 729-731
29. Peavy, G. M., Lange, K. L., Salmon, D. P., Patterson, T. L., Goldman, S., Gamst, A. C., Mills, P. J., Khandrika, S., and Galasko, D. (2007) Biol. Psychiatry 62, 472-478
30. Wilson, R. S., Arnold, S. E., Schneider, J. A., Kelly, J. F., Tang, Y., and Bennett, D. A. (2006) Neuroepidemiology 27, 143-153
31. Thal, D. R., Holzer, M., Rüb, U., Waldmann, G., Günzel, S., Zedlick, D., and Schober, R. (2000) Exp. Neurol. 163, 98-110
32. West, M. J., Coleman, P. D., Flood, D. G., and Troncoso, J. C. (1994) Lancet 344, 769-772
33. Caccamo, A., Oddo, S., Billings, L. M., Green, K. N., Martinez-Coria, H., Fisher, A., and LaFerla, F. M. (2006) Neuron 49, 671-682
34. Buxbaum, J. D., Oishi, M., Chen, H. I., Pinkas-Kramarski, R., Jaffe, E. A., Gandy, S. E., and Greengard, P. (1992) Proc. Natl. Acad. Sci. U. S. A. 89, 10075-10078
35. Haring, R., Fisher, A., Marciano, D., Pittel, Z., Kloog, Y., Zuckerman, A., Eshhar, N., and Heldman, E. (1998) J. Neurochem. 71, 2094-2103
36. Butterfield, D. A., and Boyd-Kimball, D. (2004) Brain Pathol. 14, 426-432
37. Johnson, G. V., Cox, T. M., Lockhart, J. P., Zinnerman, M. D., Miller, M. L., and Powers, R. E. (1997) Brain Res. 751, 323-329
38. Bonelli, R. M., Aschoff, A., Niederwieser, G., Heuberger, C., and Jirikowski, G. (2002) Neurobiol. Dis. 11, 106-110
39. Wess, J., Eglen, R. M., and Gautam, D. (2007) Nat. Rev. Drug Discov. 6, 721-733
40. Nürnberg, A., Bräuer, A. U., Wettschureck, N., and Offermanns, S. (2008) J. Biol. Chem. 283, 35526-35531
41. AbdAlla, S., Lother, H., el Missiry, A., Sergeev, P., Langer, A., el Faramawy, Y., and Quitterer, U. (2009) J. Biol. Chem. 284, 6566-6574