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Volumn 786, Issue , 1996, Pages 294-304

Receptor-effector coupling dysfunctions in Alzheimer's disease

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; GUANINE NUCLEOTIDE BINDING PROTEIN; INOSITOL 1,4,5 TRISPHOSPHATE; NEUROTRANSMITTER; NEUROTRANSMITTER RECEPTOR; PROTEIN KINASE C;

EID: 0029778243     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.1996.tb39072.x     Document Type: Conference Paper
Times cited : (25)

References (72)
  • 1
    • 0000383864 scopus 로고
    • Ageing and the dementias
    • J. H. Adams, J. A. N. Corsellis & L. W. Duchen, Eds. John Wiley & Sons Inc. New York
    • TOMLINSON, B. E. & J. A. N. CORSELLIS. 1984. Ageing and the dementias. In Greenfield's Neuropathology. 4th edit. J. H. Adams, J. A. N. Corsellis & L. W. Duchen, Eds. 951-1025. John Wiley & Sons Inc. New York.
    • (1984) Greenfield's Neuropathology. 4th Edit. , pp. 951-1025
    • Tomlinson, B.E.1    Corsellis, J.A.N.2
  • 2
    • 0000354585 scopus 로고
    • Structural basis of the cognitive alterations in Alzheimer's disease
    • R. D. Terry, R. Katzman & K. L. Bick, Eds. Raven Press. New York
    • TERRY, R. D., E. MASLIAH & L. A. HANSEN. 1994. Structural basis of the cognitive alterations in Alzheimer's disease. In Alzheimer's Disease. R. D. Terry, R. Katzman & K. L. Bick, Eds. 179-196. Raven Press. New York.
    • (1994) Alzheimer's Disease , pp. 179-196
    • Terry, R.D.1    Masliah, E.2    Hansen, L.A.3
  • 3
    • 0002589743 scopus 로고
    • Neurochemical basis of dementia of the Alzheimer type: Contribution of postmortem and antemortem studies
    • C. J. Fowler, L. A. Carlson, C. G. Gottfries & B. Winblad, Eds. Smith-Gordon & Co Ltd. London
    • PALMER, A. M. & D. M. BOWEN. 1990. Neurochemical basis of dementia of the Alzheimer type: contribution of postmortem and antemortem studies. In Biological Markers in Dementia of Alzheimer Type. C. J. Fowler, L. A. Carlson, C. G. Gottfries & B. Winblad, Eds. 89-105. Smith-Gordon & Co Ltd. London.
    • (1990) Biological Markers in Dementia of Alzheimer Type , pp. 89-105
    • Palmer, A.M.1    Bowen, D.M.2
  • 5
    • 0026676398 scopus 로고
    • Neurotransmitter, receptor, and signal transduction disturbances in Alzheimer's disease
    • FOWLER, C. J., C. O'NEILL, B. WINBLAD & R. F. COWBURN. 1992. Neurotransmitter, receptor, and signal transduction disturbances in Alzheimer's disease. Acta Neurol. Scand. 139(Suppl.): 59-62.
    • (1992) Acta Neurol. Scand. , vol.139 , Issue.SUPPL. , pp. 59-62
    • Fowler, C.J.1    O'Neill, C.2    Winblad, B.3    Cowburn, R.F.4
  • 9
    • 0023000880 scopus 로고
    • Density and distribution of NMDA receptors in the human hippocampus in Alzheimer's disease
    • GEDDES, J. W., H. CHANG-CHUI, S. M. COOPER, I. T. LOTT & C. W. COTMAN. 1986. Density and distribution of NMDA receptors in the human hippocampus in Alzheimer's disease. Brain Res. 399: 156-161.
    • (1986) Brain Res. , vol.399 , pp. 156-161
    • Geddes, J.W.1    Chang-Chui, H.2    Cooper, S.M.3    Lott, I.T.4    Cotman, C.W.5
  • 10
    • 0028095980 scopus 로고
    • Preservation of redox, polyamine and glycine modulatory domains of the N-methyl-D-aspartate receptor in Alzheimer's disease
    • PALMER, A. M. & M. A. BURNS. 1994. Preservation of redox, polyamine and glycine modulatory domains of the N-methyl-D-aspartate receptor in Alzheimer's disease. J. Neurochem. 62: 187-196.
    • (1994) J. Neurochem. , vol.62 , pp. 187-196
    • Palmer, A.M.1    Burns, M.A.2
  • 11
    • 0025138490 scopus 로고
    • Differential alterations of cortical glutaminergic binding sites in senile dementia of the Alzheimer type
    • CHALMERS, D. T., D. DEWAR, D. I. GRAHAM, D. N. BROOKS & J. MCCULLOCH. 1990. Differential alterations of cortical glutaminergic binding sites in senile dementia of the Alzheimer type. Proc. Natl. Acad. Sci. USA 87: 1352-1356.
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 1352-1356
    • Chalmers, D.T.1    Dewar, D.2    Graham, D.I.3    Brooks, D.N.4    Mcculloch, J.5
  • 12
    • 0024562425 scopus 로고
    • Characterization, density and distribution of kainate receptors in normal and Alzheimer's diseased brain
    • COWBURN, R. F., J. A. HARDY, R. BRIGGS & P. J. ROBERTS. 1989. Characterization, density and distribution of kainate receptors in normal and Alzheimer's diseased brain. J. Neurochem. 52: 140-147.
    • (1989) J. Neurochem. , vol.52 , pp. 140-147
    • Cowburn, R.F.1    Hardy, J.A.2    Briggs, R.3    Roberts, P.J.4
  • 14
    • 0021962590 scopus 로고
    • Loss of M2 muscarine receptors in the cerebral cortex in Alzheimer's disease and experimental cholinergic denervation
    • MASH, D. C., D. D. FLYNN & L. T. PORTER. 1985. Loss of M2 muscarine receptors in the cerebral cortex in Alzheimer's disease and experimental cholinergic denervation. Science. 228: 1115-1117.
    • (1985) Science , vol.228 , pp. 1115-1117
    • Mash, D.C.1    Flynn, D.D.2    Porter, L.T.3
  • 15
    • 0022792901 scopus 로고
    • Biochemical characterization of α-adrenergic receptors in human brain and changes in Alzheimer-type dementia
    • SHIMOHAMA, S., T. TANIGUCHI, M. FUJIWARA & M. KAMEYAMA. 1986. Biochemical characterization of α-adrenergic receptors in human brain and changes in Alzheimer-type dementia. J. Neurochem. 47: 1294-1301.
    • (1986) J. Neurochem. , vol.47 , pp. 1294-1301
    • Shimohama, S.1    Taniguchi, T.2    Fujiwara, M.3    Kameyama, M.4
  • 16
    • 0026069017 scopus 로고
    • 3H]p-aminoclonidine binding in prefrontal cortex
    • 3H]p-aminoclonidine binding in prefrontal cortex. Neurobiol. Aging 12: 131-136.
    • (1991) Neurobiol. Aging , vol.12 , pp. 131-136
    • Kalaria, R.N.1    Andorn, A.C.2
  • 17
    • 0023475270 scopus 로고
    • Changes in β-adrenergic receptor subtypes in Alzheimer-type dementia
    • SHIMOHAMA, S., T. TANIGUCHI, M. FUJIWARA & M. KAMEYAMA. 1987. Changes in β-adrenergic receptor subtypes in Alzheimer-type dementia. J. Neurochem. 48: 1215-1221.
    • (1987) J. Neurochem. , vol.48 , pp. 1215-1221
    • Shimohama, S.1    Taniguchi, T.2    Fujiwara, M.3    Kameyama, M.4
  • 18
    • 0022649383 scopus 로고
    • Binding of the novel serotonin agonist 8-hydroxy-2-(di-n-propylamino)tetralin in normal and Alzheimer brain
    • MIDDLEMISS, D. N., A. M. PALMER, N. EDEL & D. M. BOWEN. 1986. Binding of the novel serotonin agonist 8-hydroxy-2-(di-n-propylamino)tetralin in normal and Alzheimer brain. J. Neurochem. 46: 993-996.
    • (1986) J. Neurochem. , vol.46 , pp. 993-996
    • Middlemiss, D.N.1    Palmer, A.M.2    Edel, N.3    Bowen, D.M.4
  • 19
    • 0021241303 scopus 로고
    • Studies on neurotransmitter receptor systems in the neocortex and hippocampus in senile dementia of the Alzheimer type
    • CROSS, A. J., T. J. CROW, J. A. JOHNSON, E. K. PERRY, R. H. PERRY, G. BLESSED & B. E. TOMLINSON. 1984. Studies on neurotransmitter receptor systems in the neocortex and hippocampus in senile dementia of the Alzheimer type. J. Neural. Sci. 64: 109-117.
    • (1984) J. Neural. Sci. , vol.64 , pp. 109-117
    • Cross, A.J.1    Crow, T.J.2    Johnson, J.A.3    Perry, E.K.4    Perry, R.H.5    Blessed, G.6    Tomlinson, B.E.7
  • 20
    • 0023161657 scopus 로고
    • A receptors in Alzheimer's disease: A quantitative autoradiographic study
    • A receptors in Alzheimer's disease: a quantitative autoradiographic study. Neurology 37: 1454-1459.
    • (1987) Neurology , vol.37 , pp. 1454-1459
    • Chu, D.C.1    Penney, J.B.2    Young, A.B.3
  • 21
    • 0028985811 scopus 로고
    • 1 opioid receptor recognition site density and regulation by G-proteins in the temporal cortex of patients with Alzheimer's disease
    • 1 opioid receptor recognition site density and regulation by G-proteins in the temporal cortex of patients with Alzheimer's disease. Neurosci. Lett. 185: 131-134.
    • (1995) Neurosci. Lett. , vol.185 , pp. 131-134
    • Garlind, A.1    Cowburn, R.F.2    Wiehager, B.3    Ravid, R.4    Winblad, B.5    Fowler, C.J.6
  • 24
    • 0023521088 scopus 로고
    • Reduced phosphoinositide concentrations in anterior temporal cortex of Alzheimer-diseased brains
    • STOKES, C. E. & J. N. HAWTHORNE. 1987. Reduced phosphoinositide concentrations in anterior temporal cortex of Alzheimer-diseased brains. J. Neurochem. 48: 1018-1021.
    • (1987) J. Neurochem. , vol.48 , pp. 1018-1021
    • Stokes, C.E.1    Hawthorne, J.N.2
  • 25
    • 0026550678 scopus 로고
    • Adenylyl cyclase activity in post-mortem human brain: Evidence of altered G protein mediation in Alzheimer's disease
    • COWBURN, R. F., C. O'NEILL, R. RAVID, I. ALAFUZOFF, B. WINBLAD C. J. FOWLER. 1992. Adenylyl cyclase activity in post-mortem human brain: evidence of altered G protein mediation in Alzheimer's disease. J. Neurochem. 58: 1409-1419.
    • (1992) J. Neurochem. , vol.58 , pp. 1409-1419
    • Cowburn, R.F.1    O'Neill, C.2    Ravid, R.3    Alafuzoff, I.4    Winblad, B.5    Fowler, C.J.6
  • 27
    • 0028304198 scopus 로고
    • Receptor-mediated activation of G proteins is reduced in postmortem brains from Alzheimer's disease patients
    • WANG, H-Y. & E. FRIEDMAN. 1994. Receptor-mediated activation of G proteins is reduced in postmortem brains from Alzheimer's disease patients. Neurosci. Lett. 173: 37-39.
    • (1994) Neurosci. Lett. , vol.173 , pp. 37-39
    • Wang, H.-Y.1    Friedman, E.2
  • 30
    • 0027279564 scopus 로고
    • Alterations in the activity of adenylate cyclase and high affinity GTPase in Alzheimer's disease
    • ROSS, B. M., M. MCLAUGHLIN, M. ROBERTS, G. MILLIGAN, J. MCCULLOCH & J. T. KNOWLER. 1993. Alterations in the activity of adenylate cyclase and high affinity GTPase in Alzheimer's disease. Brain Res. 622: 35-42.
    • (1993) Brain Res. , vol.622 , pp. 35-42
    • Ross, B.M.1    Mclaughlin, M.2    Roberts, M.3    Milligan, G.4    Mcculloch, J.5    Knowler, J.T.6
  • 31
    • 0028031955 scopus 로고
    • Regionally selective alterations in G protein subunit levels in the Alzheimer's disease brain
    • O'NEILL, C., B. WIEHAGER, C. J. FOWLER, R. RAVID, B. WINBLAD & R. F. COWBURN. 1994. Regionally selective alterations in G protein subunit levels in the Alzheimer's disease brain. Brain Res. 636: 193-201.
    • (1994) Brain Res. , vol.636 , pp. 193-201
    • O'Neill, C.1    Wiehager, B.2    Fowler, C.J.3    Ravid, R.4    Winblad, B.5    Cowburn, R.F.6
  • 35
    • 0026046027 scopus 로고
    • Regional distribution of somatostatin receptor binding and modulation of adenylyl cyclase activity in Alzheimer's disease brain
    • BERGSTRÖM, L., A. GARLIND, L. NILSSON, I. ALAFUZOFF, C. J. FOWLER, B. WINBLAD & R. F. COWBURN. 1991. Regional distribution of somatostatin receptor binding and modulation of adenylyl cyclase activity in Alzheimer's disease brain. J. Neurol. Sci. 105: 225-233.
    • (1991) J. Neurol. Sci. , vol.105 , pp. 225-233
    • Bergström, L.1    Garlind, A.2    Nilsson, L.3    Alafuzoff, I.4    Fowler, C.J.5    Winblad, B.6    Cowburn, R.F.7
  • 36
    • 0027389045 scopus 로고
    • Reduced density of adenosine A1 receptors and preserved coupling of adenosine A1 receptors to G proteins in Alzheimer hippocampus: A quantitative autoradiographic study
    • ULAS, J., L. C. BRUNNER, L. NGUYEN & C. W. COTMAN. 1993. Reduced density of adenosine A1 receptors and preserved coupling of adenosine A1 receptors to G proteins in Alzheimer hippocampus: a quantitative autoradiographic study. Neuroscience 52: 843-854.
    • (1993) Neuroscience , vol.52 , pp. 843-854
    • Ulas, J.1    Brunner, L.C.2    Nguyen, L.3    Cotman, C.W.4
  • 37
    • 0028812365 scopus 로고
    • Preservation of acetylcholine muscarinic M2 receptor G-protein interactions in the neocortex of patients with Alzheimer's disease
    • HERNANDÉZ-HERNANDÉZ, A., A. ADEM, R. RAVID & R. F. COWBURN. 1995. Preservation of acetylcholine muscarinic M2 receptor G-protein interactions in the neocortex of patients with Alzheimer's disease. Neurosci. Lett. 186: 57-60.
    • (1995) Neurosci. Lett. , vol.186 , pp. 57-60
    • Hernandéz-Hernandéz, A.1    Adem, A.2    Ravid, R.3    Cowburn, R.F.4
  • 38
    • 0024592268 scopus 로고
    • 3H]oxotremorine-M binding in normal and Alzheimer's disease parietal cortex: An index of muscarinic receptor-G protein coupling
    • 3H]oxotremorine-M binding in normal and Alzheimer's disease parietal cortex: an index of muscarinic receptor-G protein coupling. Biochem. Soc. Trans. 17: 202-203.
    • (1989) Biochem. Soc. Trans. , vol.17 , pp. 202-203
    • Smith, C.J.1    Perry, E.K.2    Birdsall, N.J.M.3
  • 39
    • 0026090446 scopus 로고
    • Reduced basal and stimulated (isoprenaline, Gpp(NH)p, forskolin) adenylate cyclase activity in Alzheimer's disease correlated with histopathological changes
    • OHM, T. G., J. BOHL & B. LEMMER. 1991. Reduced basal and stimulated (isoprenaline, Gpp(NH)p, forskolin) adenylate cyclase activity in Alzheimer's disease correlated with histopathological changes. Brain Res. 540: 229-236.
    • (1991) Brain Res. , vol.540 , pp. 229-236
    • Ohm, T.G.1    Bohl, J.2    Lemmer, B.3
  • 41
    • 0024156354 scopus 로고
    • VIP-sensitive adenylate cyclase, guanylate cyclase, muscarinic receptors, choline acetyltransferase and acetylcholinesterase in brain tissue afflicted by Alzheimer's disease/senile dementia of the Alzheimer type
    • DANIELSSON, E., S-Å. ECKERNÄS, A. WESTLIND-DANIELSSON, Ö. NORDSTRÖM, T. BARTFAI, C-G. GOTTFRIES & A. WALLIN. 1988. VIP-sensitive adenylate cyclase, guanylate cyclase, muscarinic receptors, choline acetyltransferase and acetylcholinesterase in brain tissue afflicted by Alzheimer's disease/senile dementia of the Alzheimer type. Neurobiol. Aging 9: 153-162.
    • (1988) Neurobiol. Aging , vol.9 , pp. 153-162
    • Danielsson, E.1    Eckernäs, S.-Å.2    Westlind-Danielsson, A.3    Nordström, Ö.4    Bartfai, T.5    Gottfries, C.-G.6    Wallin, A.7
  • 42
    • 0028224211 scopus 로고
    • Adenylyl cyclase activity in Alzheimer's disease brain: Stimulatory and inhibitory signal transduction pathways are differently affected
    • SCHNECKO, A., K. WITTE, J. BOHL, T. OHM & B. LEMMER. 1994. Adenylyl cyclase activity in Alzheimer's disease brain: stimulatory and inhibitory signal transduction pathways are differently affected. Brain Res. 644: 291-296.
    • (1994) Brain Res. , vol.644 , pp. 291-296
    • Schnecko, A.1    Witte, K.2    Bohl, J.3    Ohm, T.4    Lemmer, B.5
  • 45
    • 0025917596 scopus 로고
    • Reduced in vitro phosphorylation of synapsin I (site 1) in Alzheimer's disease postmortem samples
    • PARKS, K. M., J. E. SUGAR, V. HAROUTUNIAN, L. BIERER, D. PERL & W. C. WALLACE. 1991. Reduced in vitro phosphorylation of synapsin I (site 1) in Alzheimer's disease postmortem samples. Mol. Brain Res. 9: 125-134.
    • (1991) Mol. Brain Res. , vol.9 , pp. 125-134
    • Parks, K.M.1    Sugar, J.E.2    Haroutunian, V.3    Bierer, L.4    Perl, D.5    Wallace, W.C.6
  • 50
    • 0024434989 scopus 로고
    • Ouabain binding in the human brain. Effects of Alzheimer's disease and aging
    • HARIK, S. I., M. J. MITCHELL & R. N. KALARIA. 1989. Ouabain binding in the human brain. Effects of Alzheimer's disease and aging. Arch. Neurol. 46: 951-954.
    • (1989) Arch. Neurol. , vol.46 , pp. 951-954
    • Harik, S.I.1    Mitchell, M.J.2    Kalaria, R.N.3
  • 51
    • 0026530110 scopus 로고
    • 2+-binding proteins in human neurodegenerative disorders
    • 2+-binding proteins in human neurodegenerative disorders. Trends Neurosci. 15: 259-264.
    • (1992) Trends Neurosci. , vol.15 , pp. 259-264
    • Heemann, C.W.1    Braun, K.2
  • 52
    • 0027244664 scopus 로고
    • Altered β-adrenergic receptor-stimulated cAMP formation in cultured skin fibroblasts from Alzheimer donors
    • HUANG, H-M. & G. E. GIBSON. 1993. Altered β-adrenergic receptor-stimulated cAMP formation in cultured skin fibroblasts from Alzheimer donors. J. Biol. Chem. 268: 14616-14621.
    • (1993) J. Biol. Chem. , vol.268 , pp. 14616-14621
    • Huang, H.-M.1    Gibson, G.E.2
  • 53
    • 1842367594 scopus 로고
    • Cultured skin fibroblasts, "Alzheimer antigens," and cellular calcium homeostasis in Alzheimer's disease
    • C. J. Fowler, L. A. Carlson, C. G. Gottfries & B. Winblad, Eds. Smith-Gordon & Co, Ltd. London
    • BLASS, J. P., G. E. GIBSON, R. S. BLACK, L-W. KO & K.-F. R. SHEU. 1990. Cultured skin fibroblasts, "Alzheimer antigens," and cellular calcium homeostasis in Alzheimer's disease. In Biological Markers in Dementia of Alzheimer Type. C. J. Fowler, L. A. Carlson, C. G. Gottfries & B. Winblad, Eds. 203-214. Smith-Gordon & Co, Ltd. London.
    • (1990) Biological Markers in Dementia of Alzheimer Type , pp. 203-214
    • Blass, J.P.1    Gibson, G.E.2    Black, R.S.3    Ko, L.-W.4    Sheu, K.-F.R.5
  • 55
    • 0027258552 scopus 로고
    • Coupling of muscarinic receptors to GTP proteins in postmortem human brain-alterations in Alzheimer's disease
    • WARPMAN, U., I. ALAFUZOFF & A. NORDBERG. 1993. Coupling of muscarinic receptors to GTP proteins in postmortem human brain-alterations in Alzheimer's disease. Neurosci. Lett. 150: 39-43.
    • (1993) Neurosci. Lett. , vol.150 , pp. 39-43
    • Warpman, U.1    Alafuzoff, I.2    Nordberg, A.3
  • 56
    • 0026570528 scopus 로고
    • β-Amyloid peptides destabilize calcium homeostasis and render human cortical neurons vulnerable to excitotoxicity
    • MATTSON, M. P., B. CHENG, D. DAVIS, K. BRYANT, I. LIEBERBURG & R. E. RYDEL. 1992. β-Amyloid peptides destabilize calcium homeostasis and render human cortical neurons vulnerable to excitotoxicity. J. Neurosci. 12: 376-389.
    • (1992) J. Neurosci. , vol.12 , pp. 376-389
    • Mattson, M.P.1    Cheng, B.2    Davis, D.3    Bryant, K.4    Lieberburg, I.5    Rydel, R.E.6
  • 57
    • 0026597063 scopus 로고
    • Alzheimer's disease: The amyloid cascade hypothesis
    • HARDY, J. A. & G. A. HIGGINS. 1992. Alzheimer's disease: the amyloid cascade hypothesis. Science 256: 184-185.
    • (1992) Science , vol.256 , pp. 184-185
    • Hardy, J.A.1    Higgins, G.A.2
  • 59
  • 60
    • 0028148893 scopus 로고
    • Effects of Alzheimer's disease-related β amyloid protein fragments on enzymes metabolizing phosphoinositides in brain
    • WALLACE, M. A. 1994. Effects of Alzheimer's disease-related β amyloid protein fragments on enzymes metabolizing phosphoinositides in brain. Biochim. Biophys. Acta 1227: 183-187.
    • (1994) Biochim. Biophys. Acta , vol.1227 , pp. 183-187
    • Wallace, M.A.1
  • 61
    • 0028989045 scopus 로고
    • β-Amyloid peptides enhance binding of the calcium mobilizing second messengers, inositol(1,4,5)trisphosphate and inositol-(1,3,4,5)tetrakisphosphate to their receptor sites in rat cortical membranes
    • COWBURN, R. F., B. WIEHAGER & E. SUNDSTRÖM. 1995. β-Amyloid peptides enhance binding of the calcium mobilizing second messengers, inositol(1,4,5)trisphosphate and inositol-(1,3,4,5)tetrakisphosphate to their receptor sites in rat cortical membranes. Neurosci. Lett. 191: 31-34.
    • (1995) Neurosci. Lett. , vol.191 , pp. 31-34
    • Cowburn, R.F.1    Wiehager, B.2    Sundström, E.3
  • 62
    • 0027474051 scopus 로고
    • Widespread activation of calcium-activated neutral protease (calpain) in the brain in Alzheimer disease: A potential molecular basis of neuronal degeneration
    • SAITO, K-I., J. S. ELCE, J. E. HAMOS & R. A. NIXON. 1993. Widespread activation of calcium-activated neutral protease (calpain) in the brain in Alzheimer disease: a potential molecular basis of neuronal degeneration. Proc. Natl. Acad. Sci. USA 90: 2628-2632.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 2628-2632
    • Saito, K.-I.1    Elce, J.S.2    Hamos, J.E.3    Nixon, R.A.4
  • 64
    • 0026662356 scopus 로고
    • Secretory processing of the Alzheimer amyloid β/A4 protein precursor is increased by protein phosphorylation. Biochem
    • GILLESPIE, S. L., T. E. GOLDE & S. G. YOUNKIN. 1992. Secretory processing of the Alzheimer amyloid β/A4 protein precursor is increased by protein phosphorylation. Biochem. Biophys. Res. Commun. 187: 1285-1290.
    • (1992) Biophys. Res. Commun. , vol.187 , pp. 1285-1290
    • Gillespie, S.L.1    Golde, T.E.2    Younkin, S.G.3
  • 66
    • 0027435535 scopus 로고
    • Protein phosphorylation inhibits production of Alzheimer amyloid β/A4 peptide
    • BUXBAUM, J. D., E. H. KOO & P. GREENGARD. 1993. Protein phosphorylation inhibits production of Alzheimer amyloid β/A4 peptide. Proc. Natl. Acad. Sci. USA 90: 9195-9198.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 9195-9198
    • Buxbaum, J.D.1    Koo, E.H.2    Greengard, P.3
  • 67
    • 0026476297 scopus 로고
    • Release of Alzheimer amyloid precursor derivatives stimulated by activation of muscarinic acetylcholine receptors
    • NITSCH, R. M., B. E. SLACK, R. J. WURTMAN & J. H. GROWDON. 1992. Release of Alzheimer amyloid precursor derivatives stimulated by activation of muscarinic acetylcholine receptors. Science. 255: 304-307.
    • (1992) Science , vol.255 , pp. 304-307
    • Nitsch, R.M.1    Slack, B.E.2    Wurtman, R.J.3    Growdon, J.H.4
  • 69
    • 0027209083 scopus 로고
    • Release of amyloid β-protein precursor derivatives by electrical depolarization of rat hippocampal slices
    • NITSCH, R. M., S. A. FARBER, J. H. GROWDON & R. J. WURTMAN. 1993. Release of amyloid β-protein precursor derivatives by electrical depolarization of rat hippocampal slices. Proc. Natl. Acad. Sci. USA 90: 5191-5193.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 5191-5193
    • Nitsch, R.M.1    Farber, S.A.2    Growdon, J.H.3    Wurtman, R.J.4
  • 70
    • 0028201847 scopus 로고
    • Role of neurotransmission in the regulation of amyloid β-protein precursor processing
    • NITSCH, R. M. & J. H. GROWDON. 1994. Role of neurotransmission in the regulation of amyloid β-protein precursor processing. Biochem. Pharmacol. 47: 1275-1284.
    • (1994) Biochem. Pharmacol. , vol.47 , pp. 1275-1284
    • Nitsch, R.M.1    Growdon, J.H.2


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