-
1
-
-
35448950741
-
Cardiofaciocutaneous (CFC) syndrome associated with muscular coenzyme Q10 deficiency
-
Aeby A, Sznajer Y, Cave H, Rebuffat E, van Coster R, Rigal O, van Bogaert P. 2007. Cardiofaciocutaneous (CFC) syndrome associated with muscular coenzyme Q10 deficiency. J Inherit Metab Dis 30:827.
-
(2007)
J Inherit Metab Dis
, vol.30
, pp. 827
-
-
Aeby, A.1
Sznajer, Y.2
Cave, H.3
Rebuffat, E.4
Van Coster, R.5
Rigal, O.6
Van Bogaert, P.7
-
2
-
-
33644900983
-
Coenzyme Q is irreplaceable by demethoxy-coenzyme Q in plasma membrane of Caenorhabditis elegans
-
Arroyo A, Santos-Ocana C, Ruiz-Ferrer M, Padilla S, Gavilan A, Rodriguez-Aguilera JC, Navas P. 2006. Coenzyme Q is irreplaceable by demethoxy-coenzyme Q in plasma membrane of Caenorhabditis elegans. FEBS Lett 580:1740-1746.
-
(2006)
FEBS Lett
, vol.580
, pp. 1740-1746
-
-
Arroyo, A.1
Santos-Ocana, C.2
Ruiz-Ferrer, M.3
Padilla, S.4
Gavilan, A.5
Rodriguez-Aguilera, J.C.6
Navas, P.7
-
3
-
-
77950342760
-
Coenzyme Q10 deficiencies in neuromuscular diseases
-
Artuch R, Salviati L, Jackson S, Hirano M, Navas P. 2009. Coenzyme Q10 deficiencies in neuromuscular diseases. Adv Exp Med Biol 652:117-128.
-
(2009)
Adv Exp Med Biol
, vol.652
, pp. 117-128
-
-
Artuch, R.1
Salviati, L.2
Jackson, S.3
Hirano, M.4
Navas, P.5
-
4
-
-
59049084701
-
Coenzyme Q supports distinct developmental processes in Caenorhabditis elegans
-
Asencio C, Navas P, Cabello J, Schnabel R, Cypser JR, Johnson TE, Rodriguez-Aguilera JC. 2009. Coenzyme Q supports distinct developmental processes in Caenorhabditis elegans. Mech Ageing Dev 130:145-153.
-
(2009)
Mech Ageing Dev
, vol.130
, pp. 145-153
-
-
Asencio, C.1
Navas, P.2
Cabello, J.3
Schnabel, R.4
Cypser, J.R.5
Johnson, T.E.6
Rodriguez-Aguilera, J.C.7
-
5
-
-
0038380464
-
Silencing of ubiquinone biosynthesis genes extends life span in Caenorhabditis elegans
-
Asencio C, Rodriguez-Aguilera JC, Ruiz-Ferrer M, Vela J, Navas P. 2003. Silencing of ubiquinone biosynthesis genes extends life span in Caenorhabditis elegans. FASEB J 17:1135-1137.
-
(2003)
FASEB J
, vol.17
, pp. 1135-1137
-
-
Asencio, C.1
Rodriguez-Aguilera, J.C.2
Ruiz-Ferrer, M.3
Vela, J.4
Navas, P.5
-
6
-
-
0026731820
-
COQ2 is a candidate for the structural gene encoding para-hydrox ybenzoate:polyprenyltransferase
-
Ashby MN, Kutsunai SY, Ackerman S, Tzagoloff A, Edwards PA. 1992. COQ2 is a candidate for the structural gene encoding para-hydrox ybenzoate: polyprenyltransferase. J Biol Chem 267:4128-4136.
-
(1992)
J Biol Chem
, vol.267
, pp. 4128-4136
-
-
Ashby, M.N.1
Kutsunai, S.Y.2
Ackerman, S.3
Tzagoloff, A.4
Edwards, P.A.5
-
7
-
-
4143084862
-
Progression despite replacement of a myopathic form of coenzyme Q10 defect
-
Aure K, Benoist JF, Ogier de Baulny H, Romero NB, Rigal O, Lombes A. 2004. Progression despite replacement of a myopathic form of coenzyme Q10 defect. Neurology 63:727-729.
-
(2004)
Neurology
, vol.63
, pp. 727-729
-
-
Aure, K.1
Benoist, J.F.2
Ogier De Baulny, H.3
Romero, N.B.4
Rigal, O.5
Lombes, A.6
-
8
-
-
30044432823
-
The Saccharomyces cerevisiae COQ10 gene encodes a START domain protein required for function of coenzyme Q in respiration
-
Barros MH, Johnson A, Gin P, Marbois BN, Clarke CF, Tzagoloff A. 2005. The Saccharomyces cerevisiae COQ10 gene encodes a START domain protein required for function of coenzyme Q in respiration. J Biol Chem 280:42627-42635.
-
(2005)
J Biol Chem
, vol.280
, pp. 42627-42635
-
-
Barros, M.H.1
Johnson, A.2
Gin, P.3
Marbois, B.N.4
Clarke, C.F.5
Tzagoloff, A.6
-
9
-
-
78149457379
-
The aging-associated enzyme CLK-1 is a member of the carboxylate-bridged diiron family of proteins
-
Behan RK, Lippard SJ. 2010. The aging-associated enzyme CLK-1 is a member of the carboxylate-bridged diiron family of proteins. Biochemistry 49:9679-9681.
-
(2010)
Biochemistry
, vol.49
, pp. 9679-9681
-
-
Behan, R.K.1
Lippard, S.J.2
-
11
-
-
7944237254
-
Antioxidants and radiation therapy
-
Borek C. 2004. Antioxidants and radiation therapy. J Nutr 134:3207S-3209S.
-
(2004)
J Nutr
, vol.134
-
-
Borek, C.1
-
12
-
-
73649099136
-
Evidence that ubiquinone is a required intermediate for rhodoquinone biosynthesis in Rhodospirillum rubrum
-
Brajcich BC, Iarocci AL, Johnstone LA, Morgan RK, Lonjers ZT, Hotchko MJ, Muhs JD, Kieffer A, Reynolds BJ, Mandel SM, Marbois BN, Clarke CF, Shepherd JN. 2009. Evidence that ubiquinone is a required intermediate for rhodoquinone biosynthesis in Rhodospirillum rubrum. J Bacteriol 192:436-445.
-
(2009)
J Bacteriol
, vol.192
, pp. 436-445
-
-
Brajcich, B.C.1
Iarocci, A.L.2
Johnstone, L.A.3
Morgan, R.K.4
Lonjers, Z.T.5
Hotchko, M.J.6
Muhs, J.D.7
Kieffer, A.8
Reynolds, B.J.9
Mandel, S.M.10
Marbois, B.N.11
Clarke, C.F.12
Shepherd, J.N.13
-
13
-
-
0343340109
-
Clk-1, mitochondria, and physiological rates
-
Branicky R, Benard C, Hekimi S. 2000. clk-1, mitochondria, and physiological rates. BioEssays: news and reviews in molecular, cellular and developmental biology 22:48-56.
-
(2000)
BioEssays: News and Reviews in Molecular, Cellular and Developmental Biology
, vol.22
, pp. 48-56
-
-
Branicky, R.1
Benard, C.2
Hekimi, S.3
-
14
-
-
33646583482
-
Uncoupling the pleiotropic phenotypes of clk-1 with tRNA missense suppressors in Caenorhabditis elegans
-
Branicky R, Nguyen PA, Hekimi S. 2006. Uncoupling the pleiotropic phenotypes of clk-1 with tRNA missense suppressors in Caenorhabditis elegans. Mol Cell Biol 26:3976-3985.
-
(2006)
Mol Cell Biol
, vol.26
, pp. 3976-3985
-
-
Branicky, R.1
Nguyen, P.A.2
Hekimi, S.3
-
15
-
-
0035675987
-
Phenotypic and suppressor analysis of defecation in clk-1 mutants reveals that reaction to changes in temperature is an active process in Caenorhabditis elegans
-
Branicky R, Shibata Y, Feng J, Hekimi S. 2001. Phenotypic and suppressor analysis of defecation in clk-1 mutants reveals that reaction to changes in temperature is an active process in Caenorhabditis elegans. Genetics 159:997-1006.
-
(2001)
Genetics
, vol.159
, pp. 997-1006
-
-
Branicky, R.1
Shibata, Y.2
Feng, J.3
Hekimi, S.4
-
16
-
-
1542571467
-
Molecular mechanism of maternal rescue in the clk-1 mutants of Caenorhabditis elegans
-
Burgess J, Hihi AK, Benard CY, Branicky R, Hekimi S. 2003. Molecular mechanism of maternal rescue in the clk-1 mutants of Caenorhabditis elegans. J Biol Chem, 278:49555-49562.
-
(2003)
J Biol Chem
, vol.278
, pp. 49555-49562
-
-
Burgess, J.1
Hihi, A.K.2
Benard, C.Y.3
Branicky, R.4
Hekimi, S.5
-
17
-
-
44649130654
-
Functional characterization of human COQ4, a gene required for Coenzyme Q10 biosynthesis
-
Casarin A, Jimenez-Ortega JC, Trevisson E, Pertegato V, Doimo M, Ferrero-Gomez ML, Abbadi S, Artuch R, Quinzii C, Hirano M, Basso G, Ocana CS, Navas P, Salviati L. 2008. Functional characterization of human COQ4, a gene required for Coenzyme Q10 biosynthesis. Biochem Biophys Res Commun 372:35-39.
-
(2008)
Biochem Biophys Res Commun
, vol.372
, pp. 35-39
-
-
Casarin, A.1
Jimenez-Ortega, J.C.2
Trevisson, E.3
Pertegato, V.4
Doimo, M.5
Ferrero-Gomez, M.L.6
Abbadi, S.7
Artuch, R.8
Quinzii, C.9
Hirano, M.10
Basso, G.11
Ocana, C.S.12
Navas, P.13
Salviati, L.14
-
18
-
-
0035667921
-
Biochemical functions of coenzyme Q10
-
Crane FL. 2001. Biochemical functions of coenzyme Q10. J Am Coll Nutr 20:591-598.
-
(2001)
J Am Coll Nutr
, vol.20
, pp. 591-598
-
-
Crane, F.L.1
-
19
-
-
34248150394
-
Discovery of ubiquinone (coenzyme Q) and an overview of function
-
Crane FL. 2007. Discovery of ubiquinone (coenzyme Q) and an overview of function. Mitochondrion 7 Suppl:S2-S7.
-
(2007)
Mitochondrion
, vol.7
, Issue.SUPPL.
-
-
Crane, F.L.1
-
20
-
-
58449099405
-
Coq10, a mitochondrial coenzyme Q binding protein, is required for proper respiration in Schizosaccharomyces pombe
-
Cui TZ, Kawamukai M. 2009. Coq10, a mitochondrial coenzyme Q binding protein, is required for proper respiration in Schizosaccharomyces pombe. FEBS J 276:748-759.
-
(2009)
FEBS J
, vol.276
, pp. 748-759
-
-
Cui, T.Z.1
Kawamukai, M.2
-
21
-
-
34648813720
-
ROS as signalling molecules: Mechanisms that generate specificity in ROS homeostasis
-
D'autreaux B, Toledano MB. 2007. ROS as signalling molecules: mechanisms that generate specificity in ROS homeostasis. Nat Rev Mol Cell Biol 8:813-824.
-
(2007)
Nat Rev Mol Cell Biol
, vol.8
, pp. 813-824
-
-
D'Autreaux, B.1
Toledano, M.B.2
-
22
-
-
0035859689
-
Coenzyme Q10 reverses pathological phenotype and reduces apoptosis in familial CoQ10 deficiency
-
Di Giovanni S, Mirabella M, Spinazzola A, Crociani P, Silvestri G, Broccolini A, Tonali P, Di Mauro S, Servidei S. 2001. Coenzyme Q10 reverses pathological phenotype and reduces apoptosis in familial CoQ10 deficiency. Neurology 57:515-518.
-
(2001)
Neurology
, vol.57
, pp. 515-518
-
-
Di Giovanni, S.1
Mirabella, M.2
Spinazzola, A.3
Crociani, P.4
Silvestri, G.5
Broccolini, A.6
Tonali, P.7
Di Mauro, S.8
Servidei, S.9
-
23
-
-
0030989525
-
The COQ5 gene encodes a yeast mitochondrial protein necessary for ubiquinone biosynthesis and the assembly of the respiratory chain
-
Dibrov E, Robinson KM, Lemire BD. 1997. The COQ5 gene encodes a yeast mitochondrial protein necessary for ubiquinone biosynthesis and the assembly of the respiratory chain. J Biol Chem 272:9175-9181.
-
(1997)
J Biol Chem
, vol.272
, pp. 9175-9181
-
-
Dibrov, E.1
Robinson, K.M.2
Lemire, B.D.3
-
24
-
-
34250668197
-
COQ2 nephropathy: A newly described inherited mitochondriopathy with primary renal involvement
-
Diomedi-Camassei F, Di Giandomenico S, Santorelli FM, Caridi G, Piemonte F, Montini G, Ghiggeri GM, Murer L, Barisoni L, Pastore A, Muda AO, Valente ML, Bertini E, Emma F. 2007. COQ2 nephropathy: a newly described inherited mitochondriopathy with primary renal involvement. J Am Soc Nephrol 18:2773-2780.
-
(2007)
J Am Soc Nephrol
, vol.18
, pp. 2773-2780
-
-
Diomedi-Camassei, F.1
Di Giandomenico, S.2
Santorelli, F.M.3
Caridi, G.4
Piemonte, F.5
Montini, G.6
Ghiggeri, G.M.7
Murer, L.8
Barisoni, L.9
Pastore, A.10
Muda, A.O.11
Valente, M.L.12
Bertini, E.13
Emma, F.14
-
25
-
-
0029799910
-
Enhanced sensitivity of ubiquinonedeficient mutants of Saccharomyces cerevisiae to products of autoxidized polyunsaturated fatty acids
-
Do TQ, Schultz JR, Clarke CF. 1996. Enhanced sensitivity of ubiquinonedeficient mutants of Saccharomyces cerevisiae to products of autoxidized polyunsaturated fatty acids. Proc Natl Acad Sci USA 93:7534-7539.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 7534-7539
-
-
Do, T.Q.1
Schultz, J.R.2
Clarke, C.F.3
-
26
-
-
65549087610
-
A nonsense mutation in COQ9 causes autosomal-recessive neonatal-onset primary coenzyme Q10 deficiency: A potentially treatable form of mitochondrial disease
-
Duncan AJ, Bitner-Glindzicz M, Meunier B, Costello H, Hargreaves IP, Lopez LC, Hirano M, Quinzii CM, Sadowski MI, Hardy J, Singleton A, Clayton PT, Rahman S. 2009. A nonsense mutation in COQ9 causes autosomal-recessive neonatal-onset primary coenzyme Q10 deficiency: a potentially treatable form of mitochondrial disease. Am J Hum Genet 84:558-566.
-
(2009)
Am J Hum Genet
, vol.84
, pp. 558-566
-
-
Duncan, A.J.1
Bitner-Glindzicz, M.2
Meunier, B.3
Costello, H.4
Hargreaves, I.P.5
Lopez, L.C.6
Hirano, M.7
Quinzii, C.M.8
Sadowski, M.I.9
Hardy, J.10
Singleton, A.11
Clayton, P.T.12
Rahman, S.13
-
27
-
-
77956281072
-
Coenzyme Q protects Caenorhabditis elegans GABA neurons from calciumdependent degeneration
-
Earls LR, Hacker ML, Watson JD, Miller DM, 3rd 2010. Coenzyme Q protects Caenorhabditis elegans GABA neurons from calciumdependent degeneration. Proc Natl Acad Sci USA 107:14460-14465.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 14460-14465
-
-
Earls, L.R.1
Hacker, M.L.2
Watson, J.D.3
Miller Iii., D.M.4
-
28
-
-
0029042393
-
Biochemical, physiological and medical aspects of ubiquinone function
-
Ernster L, Dallner G. 1995. Biochemical, physiological and medical aspects of ubiquinone function. Biochimica et biophysica acta 1271:195-204.
-
(1995)
Biochimica et Biophysica Acta
, vol.1271
, pp. 195-204
-
-
Ernster, L.1
Dallner, G.2
-
29
-
-
0027234508
-
Ubiquinol: An endogenous antioxidant in aerobic organisms
-
Ernster L, Forsmark-Andree P. 1993. Ubiquinol: an endogenous antioxidant in aerobic organisms. Clin Investig 71:S60-S65.
-
(1993)
Clin Investig
, vol.71
-
-
Ernster, L.1
Forsmark-Andree, P.2
-
30
-
-
4043064372
-
Mammalian pyrimidine biosynthesis: Fresh insights into an ancient pathway
-
Evans DR, Guy HI. 2004. Mammalian pyrimidine biosynthesis: fresh insights into an ancient pathway. J Biol Chem 279:33035-33038.
-
(2004)
J Biol Chem
, vol.279
, pp. 33035-33038
-
-
Evans, D.R.1
Guy, H.I.2
-
31
-
-
0031030678
-
Structural and functional conservation of the Caenorhabditis elegans timing gene clk-1
-
Ewbank JJ, Barnes TM, Lakowski B, Lussier M, Bussey H, Hekimi S. 1997. Structural and functional conservation of the Caenorhabditis elegans timing gene clk-1. Science 275:980-983.
-
(1997)
Science
, vol.275
, pp. 980-983
-
-
Ewbank, J.J.1
Barnes, T.M.2
Lakowski, B.3
Lussier, M.4
Bussey, H.5
Hekimi, S.6
-
32
-
-
79960083220
-
Probucol ameliorates renal and metabolic sequelae of primary CoQ deficiency in Pdss2 mutant mice
-
Falk MJ, Polyak E, Zhang Z, Peng M, King R, Maltzman JS, Okwuego E, Horyn O, Nakamaru-Ogiso E, Ostrovsky J, Xie LX, Chen JY, Marbois B, Nissim I, Clarke CF, Gasser DL. 2011. Probucol ameliorates renal and metabolic sequelae of primary CoQ deficiency in Pdss2 mutant mice. EMBO Mol Med 3:410-427.
-
(2011)
EMBO Mol Med
, vol.3
, pp. 410-427
-
-
Falk, M.J.1
Polyak, E.2
Zhang, Z.3
Peng, M.4
King, R.5
Maltzman, J.S.6
Okwuego, E.7
Horyn, O.8
Nakamaru-Ogiso, E.9
Ostrovsky, J.10
Xie, L.X.11
Chen, J.Y.12
Marbois, B.13
Nissim, I.14
Clarke, C.F.15
Gasser, D.L.16
-
33
-
-
0033118981
-
CLK-1 controls respiration, behavior and aging in the nematode Caenorhabditis elegans
-
Felkai S, Ewbank JJ, Lemieux J, Labbe JC, Brown GG, Hekimi S. 1999. CLK-1 controls respiration, behavior and aging in the nematode Caenorhabditis elegans. The EMBO journal 18:1783-1792.
-
(1999)
The EMBO Journal
, vol.18
, pp. 1783-1792
-
-
Felkai, S.1
Ewbank, J.J.2
Lemieux, J.3
Labbe, J.C.4
Brown, G.G.5
Hekimi, S.6
-
34
-
-
0032475979
-
A ubiquinone-binding site regulates the mitochondrial permeability transition pore
-
Fontaine E, Ichas F, Bernardi P. 1998. A ubiquinone-binding site regulates the mitochondrial permeability transition pore. J Biol Chem 273:25734-25740.
-
(1998)
J Biol Chem
, vol.273
, pp. 25734-25740
-
-
Fontaine, E.1
Ichas, F.2
Bernardi, P.3
-
35
-
-
4544375641
-
Isolation and functional expression of human COQ2, a gene encoding a polyprenyl transferase involved in the synthesis of CoQ
-
Forsgren M, Attersand A, Lake S, Grunler J, Swiezewska E, Dallner G, Climent I. 2004. Isolation and functional expression of human COQ2, a gene encoding a polyprenyl transferase involved in the synthesis of CoQ. Biochem J 382:519-526.
-
(2004)
Biochem J
, vol.382
, pp. 519-526
-
-
Forsgren, M.1
Attersand, A.2
Lake, S.3
Grunler, J.4
Swiezewska, E.5
Dallner, G.6
Climent, I.7
-
36
-
-
33746065282
-
C. elegans knockouts in ubiquinone biosynthesis genes result in different phenotypes during larval development
-
Gavilan A, Asencio C, Cabello J, Rodriguez-Aguilera JC, Schnabel R, Navas P. 2005. C. elegans knockouts in ubiquinone biosynthesis genes result in different phenotypes during larval development. Biofactors 25:21-29.
-
(2005)
Biofactors
, vol.25
, pp. 21-29
-
-
Gavilan, A.1
Asencio, C.2
Cabello, J.3
Rodriguez-Aguilera, J.C.4
Schnabel, R.5
Navas, P.6
-
37
-
-
34248171499
-
The myopathic form of coenzyme Q10 deficiency is caused by mutations in the electron-transferring-flavoprotein dehydrogenase (ETFDH) gene
-
Gempel K, Topaloglu H, Talim B, Schneiderat P, Schoser BG, Hans VH, Palmafy B, Kale G, Tokatli A, Quinzii C, Hirano M, Naini A, Dimauro S, Prokisch H, Lochmuller H, Horvath R. 2007. The myopathic form of coenzyme Q10 deficiency is caused by mutations in the electron-transferring-flavoprotein dehydrogenase (ETFDH) gene. Brain 130:2037-2044.
-
(2007)
Brain
, vol.130
, pp. 2037-2044
-
-
Gempel, K.1
Topaloglu, H.2
Talim, B.3
Schneiderat, P.4
Schoser, B.G.5
Hans, V.H.6
Palmafy, B.7
Kale, G.8
Tokatli, A.9
Quinzii, C.10
Hirano, M.11
Naini, A.12
Dimauro, S.13
Prokisch, H.14
Lochmuller, H.15
Horvath, R.16
-
38
-
-
33746040487
-
Supercomplex organization of the mitochondrial respiratory chain and the role of the Coenzyme Q pool: Pathophysiological implications
-
Genova ML, Bianchi C, Lenaz G. 2005. Supercomplex organization of the mitochondrial respiratory chain and the role of the Coenzyme Q pool: pathophysiological implications. Biofactors 25:5-20.
-
(2005)
Biofactors
, vol.25
, pp. 5-20
-
-
Genova, M.L.1
Bianchi, C.2
Lenaz, G.3
-
39
-
-
80054878669
-
New developments on the functions of coenzyme Q in mitochondria
-
Genova ML, Lenaz G. 2011. New developments on the functions of coenzyme Q in mitochondria. Biofactors 37:330-354.
-
(2011)
Biofactors
, vol.37
, pp. 330-354
-
-
Genova, M.L.1
Lenaz, G.2
-
40
-
-
0035929367
-
The site of production of superoxide radical in mitochondrial Complex i is not a bound ubisemiquinone but presumably iron-sulfur cluster N2
-
Genova ML, Ventura B, Giuliano G, Bovina C, Formiggini G, Parenti Castelli G, Lenaz G. 2001. The site of production of superoxide radical in mitochondrial Complex I is not a bound ubisemiquinone but presumably iron-sulfur cluster N2. FEBS Lett 505:364-368.
-
(2001)
FEBS Lett
, vol.505
, pp. 364-368
-
-
Genova, M.L.1
Ventura, B.2
Giuliano, G.3
Bovina, C.4
Formiggini, G.5
Parenti Castelli, G.6
Lenaz, G.7
-
41
-
-
0018158534
-
Isolation and characterization of intermediates in ubiquinone biosynthesis
-
Gibson F, Young IG. 1978. Isolation and characterization of intermediates in ubiquinone biosynthesis. Methods Enzymol 53:600-609.
-
(1978)
Methods Enzymol
, vol.53
, pp. 600-609
-
-
Gibson, F.1
Young, I.G.2
-
42
-
-
50249094970
-
The mitochondrial free radical theory of ageing-where do we stand?
-
Gruber J, Schaffer S, Halliwell B. 2008. The mitochondrial free radical theory of ageing-where do we stand? Front Biosci 13:6554-6579.
-
(2008)
Front Biosci
, vol.13
, pp. 6554-6579
-
-
Gruber, J.1
Schaffer, S.2
Halliwell, B.3
-
43
-
-
79955520308
-
COQ6 mutations in human patients produce nephrotic syndrome with sensorineural deafness
-
Heeringa SF, Chernin G, Chaki M, Zhou W, Sloan AJ, Ji Z, Xie LX, Salviati L, Hurd TW, Vega-Warner V, Killen PD, Raphael Y, Ashraf S, Ovunc B, Schoeb DS, Mclaughlin HM, Airik R, Vlangos CN, Gbadegesin R, Hinkes B, Saisawat P, Trevisson E, Doimo M, Casarin A, Pertegato V, Giorgi G, Prokisch H, Rotig A, Nurnberg G, Becker C, Wang S, Ozaltin F, Topaloglu R, Bakkaloglu A, Bakkaloglu SA, Muller D, Beissert A, Mir S, Berdeli A, Varpizen S, Zenker M, Matejas V, Santos-Ocana C, Navas P, Kusakabe T, Kispert A, Akman S, Soliman NA, Krick S, Mundel P, Reiser J, Nurnberg P, Clarke CF, Wiggins RC, Faul C, Hildebrandt F. 2011. COQ6 mutations in human patients produce nephrotic syndrome with sensorineural deafness. J Clin Invest 121:2013-2024.
-
(2011)
J Clin Invest
, vol.121
, pp. 2013-2024
-
-
Heeringa, S.F.1
Chernin, G.2
Chaki, M.3
Zhou, W.4
Sloan, A.J.5
Ji, Z.6
Xie, L.X.7
Salviati, L.8
Hurd, T.W.9
Vega-Warner, V.10
Killen, P.D.11
Raphael, Y.12
Ashraf, S.13
Ovunc, B.14
Schoeb, D.S.15
McLaughlin, H.M.16
Airik, R.17
Vlangos, C.N.18
Gbadegesin, R.19
Hinkes, B.20
Saisawat, P.21
Trevisson, E.22
Doimo, M.23
Casarin, A.24
Pertegato, V.25
Giorgi, G.26
Prokisch, H.27
Rotig, A.28
Nurnberg, G.29
Becker, C.30
Wang, S.31
Ozaltin, F.32
Topaloglu, R.33
Bakkaloglu, A.34
Bakkaloglu, S.A.35
Muller, D.36
Beissert, A.37
Mir, S.38
Berdeli, A.39
Varpizen, S.40
Zenker, M.41
Matejas, V.42
Santos-Ocana, C.43
Navas, P.44
Kusakabe, T.45
Kispert, A.46
Akman, S.47
Soliman, N.A.48
Krick, S.49
Mundel, P.50
Reiser, J.51
Nurnberg, P.52
Clarke, C.F.53
Wiggins, R.C.54
Faul, C.55
Hildebrandt, F.56
more..
-
44
-
-
0037127308
-
Ubiquinone is necessary for Caenorhabditis elegans development at mitochondrial and nonmitochondrial sites
-
Hihi AK, Gao Y, Hekimi S. 2002. Ubiquinone is necessary for Caenorhabditis elegans development at mitochondrial and nonmitochondrial sites. J Biol Chem 277:2202-2206.
-
(2002)
J Biol Chem
, vol.277
, pp. 2202-2206
-
-
Hihi, A.K.1
Gao, Y.2
Hekimi, S.3
-
45
-
-
17044454646
-
Sensitivity of Caenorhabditis elegans clk-1 mutants to ubiquinone side-chain length reveals multiple ubiquinone-dependent processes
-
Hihi AK, Kebir H, Hekimi S. 2003. Sensitivity of Caenorhabditis elegans clk-1 mutants to ubiquinone side-chain length reveals multiple ubiquinone-dependent processes. J Biol Chem 278:41013-41018.
-
(2003)
J Biol Chem
, vol.278
, pp. 41013-41018
-
-
Hihi, A.K.1
Kebir, H.2
Hekimi, S.3
-
46
-
-
84859436493
-
CoQ(10) deficiencies and MNGIE: Two treatable mitochondrial disorders
-
Hirano M, Garone C, Quinzii CM. 2012. CoQ(10) deficiencies and MNGIE: Two treatable mitochondrial disorders. Biochim Biophys Acta 1820:625-631.
-
(2012)
Biochim Biophys Acta
, vol.1820
, pp. 625-631
-
-
Hirano, M.1
Garone, C.2
Quinzii, C.M.3
-
47
-
-
0029745317
-
Complementation of coq3 mutant yeast by mitochondrial targeting of the Escherichia coli UbiG polypeptide: Evidence that UbiG catalyzes both O-methylation steps in ubiquinone biosynthesis
-
Hsu AY, Poon WW, Shepherd JA, Myles DC, Clarke CF. 1996. Complementation of coq3 mutant yeast by mitochondrial targeting of the Escherichia coli UbiG polypeptide: evidence that UbiG catalyzes both O-methylation steps in ubiquinone biosynthesis. Biochemistry 35:9797-9806.
-
(1996)
Biochemistry
, vol.35
, pp. 9797-9806
-
-
Hsu, A.Y.1
Poon, W.W.2
Shepherd, J.A.3
Myles, D.C.4
Clarke, C.F.5
-
48
-
-
84869134316
-
The submitochondrial distribution of ubiquinone affects respiration in long-lived Mclk1mice
-
Lapointe J, Wang Y, Bigras E, Hekimi S. 2012. The submitochondrial distribution of ubiquinone affects respiration in long-lived Mclk1mice. J Cell Biol 199:215-224.
-
(2012)
J Cell Biol
, vol.199
, pp. 215-224
-
-
Lapointe, J.1
Wang, Y.2
Bigras, E.3
Hekimi, S.4
-
49
-
-
0035800788
-
Mouse CLK-1 is imported into mitochondria by an unusual process that requires a leader sequence but no membrane potential
-
Jiang N, Levavasseur F, Mccright B, Shoubridge EA, Hekimi S. 2001. Mouse CLK-1 is imported into mitochondria by an unusual process that requires a leader sequence but no membrane potential. J Biol Chem 276:29218-29225.
-
(2001)
J Biol Chem
, vol.276
, pp. 29218-29225
-
-
Jiang, N.1
Levavasseur, F.2
McCright, B.3
Shoubridge, E.A.4
Hekimi, S.5
-
50
-
-
24744460063
-
COQ9, a new gene required for the biosynthesis of coenzyme Q in Saccharomyces cerevisiae
-
Johnson A, Gin P, Marbois BN, Hsieh EJ, Wu M, Barros MH, Clarke CF, Tzagoloff A. 2005. COQ9, a new gene required for the biosynthesis of coenzyme Q in Saccharomyces cerevisiae. J Biol Chem 280:31397-31404.
-
(2005)
J Biol Chem
, vol.280
, pp. 31397-31404
-
-
Johnson, A.1
Gin, P.2
Marbois, B.N.3
Hsieh, E.J.4
Wu, M.5
Barros, M.H.6
Clarke, C.F.7
Tzagoloff, A.8
-
51
-
-
0034724885
-
Isolation and functional expression of human COQ3, a gene encoding a methyltransferase required for ubiquinone biosynthesis
-
Jonassen T, Clarke CF. 2000. Isolation and functional expression of human COQ3, a gene encoding a methyltransferase required for ubiquinone biosynthesis. J Biol Chem 275:12381-12387.
-
(2000)
J Biol Chem
, vol.275
, pp. 12381-12387
-
-
Jonassen, T.1
Clarke, C.F.2
-
52
-
-
0035895199
-
A dietary source of coenzyme Q is essential for growth of long-lived Caenorhabditis elegans clk-1 mutants
-
Jonassen T, Larsen PL, Clarke CF. 2001. A dietary source of coenzyme Q is essential for growth of long-lived Caenorhabditis elegans clk-1 mutants. Proc Natl Acad Sci USA 98:421-426.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 421-426
-
-
Jonassen, T.1
Larsen, P.L.2
Clarke, C.F.3
-
53
-
-
0037160138
-
Development and fertility in Caenorhabditis elegans clk-1 mutants depend upon transport of dietary coenzyme Q8 to mitochondria
-
Jonassen T, Marbois BN, Faull KF, Clarke CF, Larsen PL. 2002. Development and fertility in Caenorhabditis elegans clk-1 mutants depend upon transport of dietary coenzyme Q8 to mitochondria. J Biol Chem 277:45020-45027.
-
(2002)
J Biol Chem
, vol.277
, pp. 45020-45027
-
-
Jonassen, T.1
Marbois, B.N.2
Faull, K.F.3
Clarke, C.F.4
Larsen, P.L.5
-
54
-
-
0032488838
-
Yeast Clk-1 homologue (Coq7/Cat5) is a mitochondrial protein in coenzyme Q synthesis
-
Jonassen T, Proft M, Randez-Gil F, Schultz JR, Marbois BN, Entian KD, Clarke CF. 1998. Yeast Clk-1 homologue (Coq7/Cat5) is a mitochondrial protein in coenzyme Q synthesis. J Biol Chem 273:3351-3357.
-
(1998)
J Biol Chem
, vol.273
, pp. 3351-3357
-
-
Jonassen, T.1
Proft, M.2
Randez-Gil, F.3
Schultz, J.R.4
Marbois, B.N.5
Entian, K.D.6
Clarke, C.F.7
-
55
-
-
0025017435
-
Nonaprenyl-4-hydroxybenzoate transferase, an enzyme involved in ubiquinone biosynthesis, in the endoplasmic reticulum-Golgi system of rat liver
-
Kalen A, Appelkvist EL, Chojnacki T, Dallner G. 1990. Nonaprenyl-4-hydroxybenzoate transferase, an enzyme involved in ubiquinone biosynthesis, in the endoplasmic reticulum-Golgi system of rat liver. J Biol Chem 265:1158-1164.
-
(1990)
J Biol Chem
, vol.265
, pp. 1158-1164
-
-
Kalen, A.1
Appelkvist, E.L.2
Chojnacki, T.3
Dallner, G.4
-
57
-
-
11144245002
-
Mitochondrial oxidative phosphorylation is defective in the long-lived mutant clk-1
-
Kayser EB, Sedensky MM, Morgan PG, Hoppel CL. 2004. Mitochondrial oxidative phosphorylation is defective in the long-lived mutant clk-1. J Biol Chem 279:54479-54486.
-
(2004)
J Biol Chem
, vol.279
, pp. 54479-54486
-
-
Kayser, E.B.1
Sedensky, M.M.2
Morgan, P.G.3
Hoppel, C.L.4
-
58
-
-
41149121580
-
ADCK3, an ancestral kinase, is mutated in a form of recessive ataxia associated with coenzyme Q10 deficiency
-
Lagier-Tourenne C, Tazir M, Lopez LC, Quinzii CM, Assoum M, Drouot N, Busso C, Makri S, Ali-Pacha L, Benhassine T, Anheim M, Lynch DR, Thibault C, Plewniak F, Bianchetti L, Tranchant C, Poch O, Dimauro S, Mandel JL, Barros MH, Hirano M, Koenig M. 2008. ADCK3, an ancestral kinase, is mutated in a form of recessive ataxia associated with coenzyme Q10 deficiency. Am J Hum Genet 82:661-672.
-
(2008)
Am J Hum Genet
, vol.82
, pp. 661-672
-
-
Lagier-Tourenne, C.1
Tazir, M.2
Lopez, L.C.3
Quinzii, C.M.4
Assoum, M.5
Drouot, N.6
Busso, C.7
Makri, S.8
Ali-Pacha, L.9
Benhassine, T.10
Anheim, M.11
Lynch, D.R.12
Thibault, C.13
Plewniak, F.14
Bianchetti, L.15
Tranchant, C.16
Poch, O.17
Dimauro, S.18
Mandel, J.L.19
Barros, M.H.20
Hirano, M.21
Koenig, M.22
more..
-
59
-
-
54449091329
-
Early mitochondrial dysfunction in longlived Mclk1mice
-
Lapointe J, Hekimi S. 2008. Early mitochondrial dysfunction in longlived Mclk1mice. J Biol Chem 283:26217-26227.
-
(2008)
J Biol Chem
, vol.283
, pp. 26217-26227
-
-
Lapointe, J.1
Hekimi, S.2
-
60
-
-
0036139856
-
The mitochondrial production of reactive oxygen species: Mechanisms and implications in human pathology
-
Lenaz G. 2001. The mitochondrial production of reactive oxygen species: mechanisms and implications in human pathology. IUBMB Life 52:159-64.
-
(2001)
IUBMB Life
, vol.52
, pp. 159-164
-
-
Lenaz, G.1
-
61
-
-
34247373746
-
Kinetics of integrated electron transfer in the mitochondrial respiratory chain random collisions vs. solid state electron channeling
-
Lenaz G, Genova ML. 2007. Kinetics of integrated electron transfer in the mitochondrial respiratory chain: random collisions vs. solid state electron channeling. Am J Physiol, Cell Physiol 292:C1221-C1239.
-
(2007)
Am J Physiol, Cell Physiol
, vol.292
-
-
Lenaz, G.1
Genova, M.L.2
-
62
-
-
66349132325
-
Mobility and function of coenzyme Q (ubiquinone) in the mitochondrial respiratory chain
-
Lenaz G, Genova ML. 2009. Mobility and function of coenzyme Q (ubiquinone) in the mitochondrial respiratory chain. Biochim Biophys Acta 1787:563-573.
-
(2009)
Biochim Biophys Acta
, vol.1787
, pp. 563-573
-
-
Lenaz, G.1
Genova, M.L.2
-
63
-
-
0031722706
-
Novel families of putative protein kinases in bacteria and archaea: Evolution of the "eukaryotic" protein kinase superfamily
-
Leonard CJ, Aravind L, Koonin EV. 1998. Novel families of putative protein kinases in bacteria and archaea: evolution of the "eukaryotic" protein kinase superfamily. Genome Res 8:1038-1047.
-
(1998)
Genome Res
, vol.8
, pp. 1038-1047
-
-
Leonard, C.J.1
Aravind, L.2
Koonin, E.V.3
-
64
-
-
0035824510
-
Ubiquinone is necessary for mouse embryonic development but is not essential for mitochondrial respiration
-
Levavasseur F, Miyadera H, Sirois J, Tremblay ML, Kita K, Shoubridge E, Hekimi S. 2001. Ubiquinone is necessary for mouse embryonic development but is not essential for mitochondrial respiration. J Biol Chem 276:46160-46164.
-
(2001)
J Biol Chem
, vol.276
, pp. 46160-46164
-
-
Levavasseur, F.1
Miyadera, H.2
Sirois, J.3
Tremblay, M.L.4
Kita, K.5
Shoubridge, E.6
Hekimi, S.7
-
65
-
-
34447295112
-
Missense mutation of the COQ2 gene causes defects of bioenergetics and de novo pyrimidine synthesis
-
Lopez-Martin JM, Salviati L, Trevisson E, Montini G, Dimauro S, Quinzii C, Hirano M, Rodriguez-Hernandez A, Cordero MD, Sanchez-Alcazar JA, Santos-Ocana C, Navas P. 2007. Missense mutation of the COQ2 gene causes defects of bioenergetics and de novo pyrimidine synthesis. Hum Mol Genet 16:1091-1097.
-
(2007)
Hum Mol Genet
, vol.16
, pp. 1091-1097
-
-
Lopez-Martin, J.M.1
Salviati, L.2
Trevisson, E.3
Montini, G.4
Dimauro, S.5
Quinzii, C.6
Hirano, M.7
Rodriguez-Hernandez, A.8
Cordero, M.D.9
Sanchez-Alcazar, J.A.10
Santos-Ocana, C.11
Navas, P.12
-
66
-
-
33845232634
-
Leigh syndrome with nephropathy and CoQ10 deficiency due to decaprenyl diphosphate synthase subunit 2 (PDSS2) mutations
-
Lopez LC, Schuelke M, Quinzii CM, Kanki T, Rodenburg RJ, Naini A, Dimauro S, Hirano M. 2006. Leigh syndrome with nephropathy and CoQ10 deficiency due to decaprenyl diphosphate synthase subunit 2 (PDSS2) mutations. Am J Hum Genet 79:1125-1129.
-
(2006)
Am J Hum Genet
, vol.79
, pp. 1125-1129
-
-
Lopez, L.C.1
Schuelke, M.2
Quinzii, C.M.3
Kanki, T.4
Rodenburg, R.J.5
Naini, A.6
Dimauro, S.7
Hirano, M.8
-
67
-
-
81955161104
-
Cerebellar defects in Pdss2 conditional knockout mice during embryonic development and in adulthood
-
Lu S, Lu LY, Liu MF, Yuan QJ, Sham MH, Guan XY, Huang JD. 2011. Cerebellar defects in Pdss2 conditional knockout mice during embryonic development and in adulthood. Neurobiol Dis 45:219-233.
-
(2011)
Neurobiol Dis
, vol.45
, pp. 219-233
-
-
Lu, S.1
Lu, L.Y.2
Liu, M.F.3
Yuan, Q.J.4
Sham, M.H.5
Guan, X.Y.6
Huang, J.D.7
-
68
-
-
77949440226
-
Coenzyme Q10 in neuromuscular and neurodegenerative disorders
-
Mancuso M, Orsucci D, Volpi L, Calsolaro V, Siciliano G. 2009. Coenzyme Q10 in neuromuscular and neurodegenerative disorders. Curr Drug Targets 11:111-121.
-
(2009)
Curr Drug Targets
, vol.11
, pp. 111-121
-
-
Mancuso, M.1
Orsucci, D.2
Volpi, L.3
Calsolaro, V.4
Siciliano, G.5
-
69
-
-
20144363128
-
Coq3 and Coq4 define a polypeptide complex in yeast mitochondria for the biosynthesis of coenzyme Q
-
Marbois B, Gin P, Faull KF, Poon WW, Lee PT, Strahan J, Shepherd JN, Clarke CF. 2005. Coq3 and Coq4 define a polypeptide complex in yeast mitochondria for the biosynthesis of coenzyme Q. J Biol Chem 280:20231-20238.
-
(2005)
J Biol Chem
, vol.280
, pp. 20231-20238
-
-
Marbois, B.1
Gin, P.2
Faull, K.F.3
Poon, W.W.4
Lee, P.T.5
Strahan, J.6
Shepherd, J.N.7
Clarke, C.F.8
-
70
-
-
57649178662
-
The yeast Coq4 polypeptide organizes a mitochondrial protein complex essential for coenzyme Q biosynthesis
-
Marbois B, Gin P, Gulmezian M, Clarke CF. 2009. The yeast Coq4 polypeptide organizes a mitochondrial protein complex essential for coenzyme Q biosynthesis. Biochim Biophys Acta 1791:69-75.
-
(2009)
Biochim Biophys Acta
, vol.1791
, pp. 69-75
-
-
Marbois, B.1
Gin, P.2
Gulmezian, M.3
Clarke, C.F.4
-
71
-
-
77956251553
-
Para-Aminobenzoic acid is a precursor in coenzyme Q6 biosynthesis in Saccharomyces cerevisiae
-
Marbois B, Xie LX, Choi S, Hirano K, Hyman K, Clarke CF. 2010. para-Aminobenzoic acid is a precursor in coenzyme Q6 biosynthesis in Saccharomyces cerevisiae. J Biol Chem 285:27827-27838.
-
(2010)
J Biol Chem
, vol.285
, pp. 27827-27838
-
-
Marbois, B.1
Xie, L.X.2
Choi, S.3
Hirano, K.4
Hyman, K.5
Clarke, C.F.6
-
72
-
-
0030063759
-
The COQ7 gene encodes a protein in saccharomyces cerevisiae necessary for ubiquinone biosynthesis
-
Marbois BN, Clarke CF. 1996. The COQ7 gene encodes a protein in saccharomyces cerevisiae necessary for ubiquinone biosynthesis. J Biol Chem 271:2995-3004.
-
(1996)
J Biol Chem
, vol.271
, pp. 2995-3004
-
-
Marbois, B.N.1
Clarke, C.F.2
-
73
-
-
80054888051
-
Respiratory-induced coenzyme Q biosynthesis is regulated by a phosphorylation cycle of Cat5p/Coq7p
-
Martin-Montalvo A, Gonzalez-Mariscal I, Padilla S, Ballesteros M, Brautigan DL, Navas P, Santos-Ocana C. 2011. Respiratory-induced coenzyme Q biosynthesis is regulated by a phosphorylation cycle of Cat5p/Coq7p. Biochem J 440:107-114.
-
(2011)
Biochem J
, vol.440
, pp. 107-114
-
-
Martin-Montalvo, A.1
Gonzalez-Mariscal, I.2
Padilla, S.3
Ballesteros, M.4
Brautigan, D.L.5
Navas, P.6
Santos-Ocana, C.7
-
74
-
-
0035949539
-
Ubiquinone biosynthesis in microorganisms
-
Meganathan R. 2001. Ubiquinone biosynthesis in microorganisms. FEMS Microbiol Lett 203:131-139.
-
(2001)
FEMS Microbiol Lett
, vol.203
, pp. 131-139
-
-
Meganathan, R.1
-
75
-
-
0035896557
-
Altered quinone biosynthesis in the long-lived clk-1 mutants of Caenorhabditis elegans
-
Miyadera H, Amino H, Hiraishi A, Taka H, Murayama K, Miyoshi H, Sakamoto K, Ishii N, Hekimi S, Kita K. 2001. Altered quinone biosynthesis in the long-lived clk-1 mutants of Caenorhabditis elegans. J Biol Chem 276:7713-7716.
-
(2001)
J Biol Chem
, vol.276
, pp. 7713-7716
-
-
Miyadera, H.1
Amino, H.2
Hiraishi, A.3
Taka, H.4
Murayama, K.5
Miyoshi, H.6
Sakamoto, K.7
Ishii, N.8
Hekimi, S.9
Kita, K.10
-
76
-
-
41149134880
-
CABC1 gene mutations cause ubiquinone deficiency with cerebellar ataxia and seizures
-
Mollet J, Delahodde A, Serre V, Chretien D, Schlemmer D, Lombes A, Boddaert N, Desguerre I, De Lonlay P, De Baulny HO, Munnich A, Rotig A. 2008. CABC1 gene mutations cause ubiquinone deficiency with cerebellar ataxia and seizures. Am J Hum Genet 82:623-630.
-
(2008)
Am J Hum Genet
, vol.82
, pp. 623-630
-
-
Mollet, J.1
Delahodde, A.2
Serre, V.3
Chretien, D.4
Schlemmer, D.5
Lombes, A.6
Boddaert, N.7
Desguerre, I.8
De Lonlay, P.9
De Baulny, H.O.10
Munnich, A.11
Rotig, A.12
-
77
-
-
33847347629
-
Prenyldiphosphate synthase, subunit 1 (PDSS1) and OH-benzoate polyprenyltransferase (COQ2) mutations in ubiquinone deficiency and oxidative phosphorylation disorders
-
Mollet J, Giurgea I, Schlemmer D, Dallner G, Chretien D, Delahodde A, Bacq D, de Lonlay P, Munnich A, Rotig A. 2007. Prenyldiphosphate synthase, subunit 1 (PDSS1) and OH-benzoate polyprenyltransferase (COQ2) mutations in ubiquinone deficiency and oxidative phosphorylation disorders. J Clin Invest 117:765-772.
-
(2007)
J Clin Invest
, vol.117
, pp. 765-772
-
-
Mollet, J.1
Giurgea, I.2
Schlemmer, D.3
Dallner, G.4
Chretien, D.5
Delahodde, A.6
Bacq, D.7
De Lonlay, P.8
Munnich, A.9
Rotig, A.10
-
78
-
-
80054870971
-
Non-mitochondrial coenzyme Q
-
Morré DJ, Morré DM. 2011. Non-mitochondrial coenzyme Q. Biofactors 37:355-360.
-
(2011)
Biofactors
, vol.37
, pp. 355-360
-
-
Morré, D.J.1
Morré, D.M.2
-
80
-
-
0035976759
-
Mouse homologue of coq7/clk-1, longevity gene in Caenorhabditis elegans, is essential for coenzyme Q synthesis, maintenance of mitochondrial integrity, and neurogenesis
-
Nakai D, Yuasa S, Takahashi M, Shimizu T, Asaumi S, Isono K, Takao T, Suzuki Y, Kuroyanagi H, Hirokawa K, Koseki H, Shirsawa T. 2001. Mouse homologue of coq7/clk-1, longevity gene in Caenorhabditis elegans, is essential for coenzyme Q synthesis, maintenance of mitochondrial integrity, and neurogenesis. Biochem Biophys Res Commun 289:463-471.
-
(2001)
Biochem Biophys Res Commun
, vol.289
, pp. 463-471
-
-
Nakai, D.1
Yuasa, S.2
Takahashi, M.3
Shimizu, T.4
Asaumi, S.5
Isono, K.6
Takao, T.7
Suzuki, Y.8
Kuroyanagi, H.9
Hirokawa, K.10
Koseki, H.11
Shirsawa, T.12
-
81
-
-
0028260509
-
One-and two-electron reduction of quinones by rat liver subcellular fractions
-
Nakamura M, Hayashi T. 1994. One-and two-electron reduction of quinones by rat liver subcellular fractions. J Biochem 115:1141-1147.
-
(1994)
J Biochem
, vol.115
, pp. 1141-1147
-
-
Nakamura, M.1
Hayashi, T.2
-
82
-
-
34248195909
-
The importance of plasma membrane coenzyme Q in aging and stress responses
-
Navas P, Villalba JM, De Cabo R. 2007. The importance of plasma membrane coenzyme Q in aging and stress responses. Mitochondrion 7 Suppl:S34-S40.
-
(2007)
Mitochondrion
, vol.7
, Issue.SUPPL.
-
-
Navas, P.1
Villalba, J.M.2
De Cabo, R.3
-
83
-
-
33746335977
-
Lysosomal ROS formation
-
Nohl H, Gille L. 2005. Lysosomal ROS formation. Redox Rep 10:199-205.
-
(2005)
Redox Rep
, vol.10
, pp. 199-205
-
-
Nohl, H.1
Gille, L.2
-
84
-
-
0032541136
-
Biological significance of the side chain length of ubiquinone in Saccharomyces cerevisiae
-
Okada K, Kainou T, Matsuda H, Kawamukai M. 1998. Biological significance of the side chain length of ubiquinone in Saccharomyces cerevisiae. FEBS Letters 431:241-244.
-
(1998)
FEBS Letters
, vol.431
, pp. 241-244
-
-
Okada, K.1
Kainou, T.2
Matsuda, H.3
Kawamukai, M.4
-
85
-
-
0030590211
-
Polyprenyl diphosphate synthase essentially defines the length of the side chain of ubiquinone
-
Okada K, Suzuki K, Kamiya Y, Zhu X, Fujisaki S, Nishimura Y, Nishino T, Nakagawa T, Kawamukai M, Matsuda H. 1996. Polyprenyl diphosphate synthase essentially defines the length of the side chain of ubiquinone. Biochim Biophys Acta 1302:217-223.
-
(1996)
Biochim Biophys Acta
, vol.1302
, pp. 217-223
-
-
Okada, K.1
Suzuki, K.2
Kamiya, Y.3
Zhu, X.4
Fujisaki, S.5
Nishimura, Y.6
Nishino, T.7
Nakagawa, T.8
Kawamukai, M.9
Matsuda, H.10
-
86
-
-
80053160231
-
Coenzyme Q biosynthesis: Coq6 is required for the C5-hydroxylation reaction and substrate analogs rescue Coq6 deficiency
-
Ozeir M, Muhlenhoff U, Webert H, Lill R, Fontecave M, Pierrel F. 2011. Coenzyme Q biosynthesis: Coq6 is required for the C5-hydroxylation reaction and substrate analogs rescue Coq6 deficiency. Chem Biol 18:1134-1142.
-
(2011)
Chem Biol
, vol.18
, pp. 1134-1142
-
-
Ozeir, M.1
Muhlenhoff, U.2
Webert, H.3
Lill, R.4
Fontecave, M.5
Pierrel, F.6
-
87
-
-
2942707861
-
Demethoxy-Q, an intermediate of coenzyme Q biosyn
-
thesis, fails to support respiration in Saccharomyces cerevisiae and lacks antioxidant activity
-
Padilla S, Jonassen T, Jimenez-Hidalgo MA, Fernandez-Ayala DJ, Lopez-Lluch G, Marbois B, Navas P, Clarke CF, Santos-Ocana C. 2004. Demethoxy-Q, an intermediate of coenzyme Q biosynthesis, fails to support respiration in Saccharomyces cerevisiae and lacks antioxidant activity. J Biol Chem 279:25995-6004.
-
(2004)
J Biol Chem
, vol.279
, pp. 25995-26004
-
-
Padilla, S.1
Jonassen, T.2
Jimenez-Hidalgo, M.A.3
Fernandez-Ayala, D.J.4
Lopez-Lluch, G.5
Marbois, B.6
Navas, P.7
Clarke, C.F.8
Santos-Ocana, C.9
-
88
-
-
58149492767
-
Hydroxylation of demethoxy-Q6 constitutes a control point in yeast coenzyme Q6 biosynthesis
-
Padilla S, Tran UC, Jimenez-Hidalgo M, Lopez-Martin JM, Martin-Montalvo A, Clarke CF, Navas P, Santos-Ocana C. 2009. Hydroxylation of demethoxy-Q6 constitutes a control point in yeast coenzyme Q6 biosynthesis. Cell Mol Life Sci 66:173-186.
-
(2009)
Cell Mol Life Sci
, vol.66
, pp. 173-186
-
-
Padilla, S.1
Tran, U.C.2
Jimenez-Hidalgo, M.3
Lopez-Martin, J.M.4
Martin-Montalvo, A.5
Clarke, C.F.6
Navas, P.7
Santos-Ocana, C.8
-
89
-
-
43249118592
-
Primary coenzyme Q deficiency in Pdss2 mutant mice causes isolated renal disease
-
Peng M, Falk MJ, Haase VH, King R, Polyak E, Selak M, Yudkoff M, Hancock WW, Meade R, Saiki R, Lunceford AL, Clarke CF, Gasser DL. 2008. Primary coenzyme Q deficiency in Pdss2 mutant mice causes isolated renal disease. PLoS Genet 4:e1000061.
-
(2008)
PLoS Genet
, vol.4
-
-
Peng, M.1
Falk, M.J.2
Haase, V.H.3
King, R.4
Polyak, E.5
Selak, M.6
Yudkoff, M.7
Hancock, W.W.8
Meade, R.9
Saiki, R.10
Lunceford, A.L.11
Clarke, C.F.12
Gasser, D.L.13
-
90
-
-
77954182740
-
Involvement of mitochondrial ferredoxin and para-aminobenzoic acid in yeast coenzyme Q biosynthesis
-
Pierrel F, Hamelin O, Douki T, Kieffer-Jaquinod S, Muhlenhoff U, Ozeir M, Lill R, Fontecave M. 2010. Involvement of mitochondrial ferredoxin and para-aminobenzoic acid in yeast coenzyme Q biosynthesis. Chemistry & Biology 17:449-459.
-
(2010)
Chemistry & Biology
, vol.17
, pp. 449-459
-
-
Pierrel, F.1
Hamelin, O.2
Douki, T.3
Kieffer-Jaquinod, S.4
Muhlenhoff, U.5
Ozeir, M.6
Lill, R.7
Fontecave, M.8
-
91
-
-
0033618376
-
Yeast and rat Coq3 and Escherichia coli UbiG polypeptides catalyze both O-methyltransferase steps in coenzyme Q biosynthesis
-
Poon WW, Barkovich RJ, Hsu AY, Frankel A, Lee PT, Shepherd JN, Myles DC, Clarke CF. 1999. Yeast and rat Coq3 and Escherichia coli UbiG polypeptides catalyze both O-methyltransferase steps in coenzyme Q biosynthesis. J Biol Chem 274:21665-21672.
-
(1999)
J Biol Chem
, vol.274
, pp. 21665-21672
-
-
Poon, W.W.1
Barkovich, R.J.2
Hsu, A.Y.3
Frankel, A.4
Lee, P.T.5
Shepherd, J.N.6
Myles, D.C.7
Clarke, C.F.8
-
92
-
-
0033820931
-
Identification of Escherichia coli ubiB, a gene required for the first monooxygenase step in ubiquinone biosynthesis
-
Poon WW, Davis DE, Ha HT, Jonassen T, Rather PN, Clarke CF. 2000. Identification of Escherichia coli ubiB, a gene required for the first monooxygenase step in ubiquinone biosynthesis. J Bacteriol 182:5139-5146.
-
(2000)
J Bacteriol
, vol.182
, pp. 5139-5146
-
-
Poon, W.W.1
Davis, D.E.2
Ha, H.T.3
Jonassen, T.4
Rather, P.N.5
Clarke, C.F.6
-
93
-
-
0030867418
-
Sensitivity to treatment with polyunsaturated fatty acids is a general characteristic of the ubiquinone-deficient yeast coq mutants
-
Poon WW, Do TQ, Marbois BN, Clarke CF. 1997. Sensitivity to treatment with polyunsaturated fatty acids is a general characteristic of the ubiquinone-deficient yeast coq mutants. Mol Aspects Med 18 Suppl, S121-S127.
-
(1997)
Mol Aspects Med
, vol.18
, Issue.SUPPL.
-
-
Poon, W.W.1
Do, T.Q.2
Marbois, B.N.3
Clarke, C.F.4
-
94
-
-
31544480133
-
A mutation in para-hydroxybenzoate-polyprenyl transferase (COQ2) causes primary coenzyme Q10 deficiency
-
Quinzii C, Naini A, Salviati L, Trevisson E, Navas P, Dimauro S, Hiranov M. 2006. A mutation in para-hydroxybenzoate-polyprenyl transferase (COQ2) causes primary coenzyme Q10 deficiency. Am J Hum Genet 78:345-349.
-
(2006)
Am J Hum Genet
, vol.78
, pp. 345-349
-
-
Quinzii, C.1
Naini, A.2
Salviati, L.3
Trevisson, E.4
Navas, P.5
Dimauro, S.6
Hiranov, M.7
-
95
-
-
77956250930
-
Coenzyme Q and mitochondrial disease
-
Quinzii CM, Hirano M. 2010. Coenzyme Q and mitochondrial disease. Dev Disabil Res Rev 16:183-188.
-
(2010)
Dev Disabil Res Rev
, vol.16
, pp. 183-188
-
-
Quinzii, C.M.1
Hirano, M.2
-
96
-
-
77957844254
-
Reactive oxygen species, oxidative stress, and cell death correlate with level of CoQ10 deficiency
-
Quinzii CM, Lopez LC, Gilkerson RW, Dorado B, Coku J, Naini AB, Lagier-Tourenne C, Schuelke M, Salviati L, Carrozzo R, Santorelli F, Rahman S, Tazir M, Koenig M, Dimauro S, Hirano M. 2010. Reactive oxygen species, oxidative stress, and cell death correlate with level of CoQ10 deficiency. FASEB J 24:3733-3743.
-
(2010)
FASEB J
, vol.24
, pp. 3733-3743
-
-
Quinzii, C.M.1
Lopez, L.C.2
Gilkerson, R.W.3
Dorado, B.4
Coku, J.5
Naini, A.B.6
Lagier-Tourenne, C.7
Schuelke, M.8
Salviati, L.9
Carrozzo, R.10
Santorelli, F.11
Rahman, S.12
Tazir, M.13
Koenig, M.14
Dimauro, S.15
Hirano, M.16
-
97
-
-
44949220201
-
Respiratory chain dysfunction and oxidative stress correlate with severity of primary CoQ10 deficiency
-
Quinzii CM, Lopez LC, von-Moltke J, Naini A, Krishna S, Schuelke M, Salviati L, Navas P, Dimauro S, Hirano M. 2008. Respiratory chain dysfunction and oxidative stress correlate with severity of primary CoQ10 deficiency. FASEB J 22:1874-1885.
-
(2008)
FASEB J
, vol.22
, pp. 1874-1885
-
-
Quinzii, C.M.1
Lopez, L.C.2
Von-Moltke, J.3
Naini, A.4
Krishna, S.5
Schuelke, M.6
Salviati, L.7
Navas, P.8
Dimauro, S.9
Hirano, M.10
-
98
-
-
84857129564
-
Effects of inhibiting CoQ10 biosynthesis with 4-nitrobenzoate in human fibroblasts
-
Quinzii CM, Tadesse S, Naini A, Hirano M. 2012. Effects of inhibiting CoQ10 biosynthesis with 4-nitrobenzoate in human fibroblasts. PLoS One 7:e30606.
-
(2012)
PLoS One
, vol.7
-
-
Quinzii, C.M.1
Tadesse, S.2
Naini, A.3
Hirano, M.4
-
100
-
-
84855992976
-
176th ENMC International Workshop: Diagnosis and treatment of coenzyme Q(1)(0) deficiency
-
Rahman S, Clarke CF, Hirano M. 2011. 176th ENMC International Workshop: diagnosis and treatment of coenzyme Q(1)(0) deficiency. Neuromuscul Disord 22:76-86.
-
(2011)
Neuromuscul Disord
, vol.22
, pp. 76-86
-
-
Rahman, S.1
Clarke, C.F.2
Hirano, M.3
-
101
-
-
77956235773
-
Bacteria, yeast, worms, and flies: Exploiting simple model organisms to investigate human mitochondrial diseases
-
Rea SL, Graham BH, Nakamaru-Ogiso E, Kar A, Falk MJ. 2010. Bacteria, yeast, worms, and flies: exploiting simple model organisms to investigate human mitochondrial diseases. Dev Disabil Res Rev 16:200-218.
-
(2010)
Dev Disabil Res Rev
, vol.16
, pp. 200-218
-
-
Rea, S.L.1
Graham, B.H.2
Nakamaru-Ogiso, E.3
Kar, A.4
Falk, M.J.5
-
102
-
-
33745631769
-
Cell signaling H2O2, a necessary evil for cell signaling
-
Rhee SG. 2006. Cell signaling. H2O2, a necessary evil for cell signaling. Science 312:1882-1883.
-
(2006)
Science
, vol.312
, pp. 1882-1883
-
-
Rhee, S.G.1
-
103
-
-
78650869592
-
Mitochondrial ROS generation and its regulation: Mechanisms involved in H(2)O(2) signaling
-
Rigoulet M, Yoboue ED, Devin A. 2010. Mitochondrial ROS generation and its regulation: mechanisms involved in H(2)O(2) signaling. Antioxidants & Redox Signaling 14:459-468.
-
(2010)
Antioxidants & Redox Signaling
, vol.14
, pp. 459-468
-
-
Rigoulet, M.1
Yoboue, E.D.2
Devin, A.3
-
104
-
-
0348049908
-
Caenorhabditis elegans ubiquinone biosynthesis genes
-
Rodríguez-Aguilera JC, Asencio C, Ruiz-Ferrer M, Vela J, Navas P. 2003. Caenorhabditis elegans ubiquinone biosynthesis genes. Biofactors 18:237-244.
-
(2003)
Biofactors
, vol.18
, pp. 237-244
-
-
Rodríguez-Aguilera, J.C.1
Asencio, C.2
Ruiz-Ferrer, M.3
Vela, J.4
Navas, P.5
-
105
-
-
58149376131
-
Coenzyme Q deficiency triggers mitochondria degradation by mitophagy
-
Rodriguez-Hernandez A, Cordero MD, Salviati L, Artuch R, Pineda M, Briones P, Gomez Izquierdo L, Cotan D, Navas P, Sanchez-Alcazar JA. 2009. Coenzyme Q deficiency triggers mitochondria degradation by mitophagy. Autophagy 5:19-32.
-
(2009)
Autophagy
, vol.5
, pp. 19-32
-
-
Rodriguez-Hernandez, A.1
Cordero, M.D.2
Salviati, L.3
Artuch, R.4
Pineda, M.5
Briones, P.6
Gomez Izquierdo, L.7
Cotan, D.8
Navas, P.9
Sanchez-Alcazar, J.A.10
-
106
-
-
34248151929
-
Infantile and pediatric quinone deficiency diseases
-
Rotig A, Mollet J, Rio M, Munnich A. 2007. Infantile and pediatric quinone deficiency diseases. Mitochondrion 7 Suppl:S112-S121.
-
(2007)
Mitochondrion
, vol.7
, Issue.SUPPL.
-
-
Rotig, A.1
Mollet, J.2
Rio, M.3
Munnich, A.4
-
107
-
-
27644497075
-
Characterization of solanesyl and decaprenyl diphosphate synthases in mice and humans
-
Saiki R, Nagata A, Kainou T, Matsuda H, Kawamukai M. 2005. Characterization of solanesyl and decaprenyl diphosphate synthases in mice and humans. FEBS J 272:5606-5622.
-
(2005)
FEBS J
, vol.272
, pp. 5606-5622
-
-
Saiki, R.1
Nagata, A.2
Kainou, T.3
Matsuda, H.4
Kawamukai, M.5
-
108
-
-
84860277256
-
Haploinsufficiency of COQ4 causes coenzyme Q10 deficiency
-
Salviati L, Trevisson E, Rodriguez Hernandez MA, Casarin A, Pertegato V, Doimo M, Cassina M, Agosto C, Desbats MA, Sartori G, Sacconi S, Memo L, Zuffardi O, Artuch R, Quinzii C, Dimauro S, Hirano M, Santos-Ocana C, Navas P. 2012. Haploinsufficiency of COQ4 causes coenzyme Q10 deficiency. J Med Genet 49:187-191.
-
(2012)
J Med Genet
, vol.49
, pp. 187-191
-
-
Salviati, L.1
Trevisson, E.2
Rodriguez Hernandez, M.A.3
Casarin, A.4
Pertegato, V.5
Doimo, M.6
Cassina, M.7
Agosto, C.8
Desbats, M.A.9
Sartori, G.10
Sacconi, S.11
Memo, L.12
Zuffardi, O.13
Artuch, R.14
Quinzii, C.15
Dimauro, S.16
Hirano, M.17
Santos-Ocana, C.18
Navas, P.19
-
110
-
-
66349120000
-
From protons to OXPHOS supercomplexes and Alzheimer's disease: Structure-dynamics-function relationships of energy-transducing membranes
-
Seelert H, Dani DN, Dante S, Hauss T, Krause F, Schafer E, Frenzel M, Poetsch A, Rexroth S, Schwassmann HJ, Suhai T, Vonck J, Dencher NA. 2009. From protons to OXPHOS supercomplexes and Alzheimer's disease: structure-dynamics- function relationships of energy-transducing membranes. Biochim Biophys Acta 1787:657-671.
-
(2009)
Biochim Biophys Acta
, vol.1787
, pp. 657-671
-
-
Seelert, H.1
Dani, D.N.2
Dante, S.3
Hauss, T.4
Krause, F.5
Schafer, E.6
Frenzel, M.7
Poetsch, A.8
Rexroth, S.9
Schwassmann, H.J.10
Suhai, T.11
Vonck, J.12
Dencher, N.A.13
-
111
-
-
0035823556
-
A new member of the family of di-iron carboxylate proteins. Coq7 (clk-1), a membrane-bound hydroxylase involved in ubiquinone biosynthesis
-
Stenmark P, Grunler J, Mattsson J, Sindelar PJ, Nordlund P, Berthold DA. 2001. A new member of the family of di-iron carboxylate proteins. Coq7 (clk-1), a membrane-bound hydroxylase involved in ubiquinone biosynthesis. J Biol Chem 276:33297-33300.
-
(2001)
J Biol Chem
, vol.276
, pp. 33297-33300
-
-
Stenmark, P.1
Grunler, J.2
Mattsson, J.3
Sindelar, P.J.4
Nordlund, P.5
Berthold, D.A.6
-
112
-
-
33751426642
-
Genetic and molecular characterization of CLK-1/mCLK1, a conserved determinant of the rate of aging
-
Stepanyan Z, Hughes B, Cliche DO, Camp D, Hekimi S. 2006. Genetic and molecular characterization of CLK-1/mCLK1, a conserved determinant of the rate of aging. Exp Gerontol 41:940-951.
-
(2006)
Exp Gerontol
, vol.41
, pp. 940-951
-
-
Stepanyan, Z.1
Hughes, B.2
Cliche, D.O.3
Camp, D.4
Hekimi, S.5
-
113
-
-
85007953567
-
Evidence that Escherichia coli ubiA product is a functional homolog of yeast COQ2, and the regulation of ubiA gene expression
-
Suzuki K, Ueda M, Yuasa M, Nakagawa T, Kawamukai M, Matsuda H. 1994. Evidence that Escherichia coli ubiA product is a functional homolog of yeast COQ2, and the regulation of ubiA gene expression. Biosci Biotechnol Biochem 58:1814-1819.
-
(1994)
Biosci Biotechnol Biochem
, vol.58
, pp. 1814-1819
-
-
Suzuki, K.1
Ueda, M.2
Yuasa, M.3
Nakagawa, T.4
Kawamukai, M.5
Matsuda, H.6
-
114
-
-
55349084786
-
Ubiquinone biosynthesis in Saccharomyces cerevisiae: The molecular organization of O-methylase Coq3p depends on Abc1p/Coq8p
-
Tauche A, Krause-Buchholz U, Rodel G. 2008. Ubiquinone biosynthesis in Saccharomyces cerevisiae: the molecular organization of O-methylase Coq3p depends on Abc1p/Coq8p. FEMS Yeast Res 8:1263-1275.
-
(2008)
FEMS Yeast Res
, vol.8
, pp. 1263-1275
-
-
Tauche, A.1
Krause-Buchholz, U.2
Rodel, G.3
-
115
-
-
0029000439
-
Relationship between the endoplasmic reticulum-Golgi membrane system and ubiquinone biosynthesis
-
Teclebrhan H, Jakobsson-Borin A, Brunk U, Dallner G. 1995. Relationship between the endoplasmic reticulum-Golgi membrane system and ubiquinone biosynthesis. Biochimica et biophysica acta 1256:157-165.
-
(1995)
Biochimica et Biophysica Acta
, vol.1256
, pp. 157-165
-
-
Teclebrhan, H.1
Jakobsson-Borin, A.2
Brunk, U.3
Dallner, G.4
-
116
-
-
0036297833
-
Ubiquinone biosynthesis in rat liver peroxisomes
-
Tekle M, Bentinger M, Nordman T, Appelkvist EL, Chojnacki T, Olsson JM. 2002. Ubiquinone biosynthesis in rat liver peroxisomes. Biochemical and biophysical research communications 291:1128-1133.
-
(2002)
Biochemical and Biophysical Research Communications
, vol.291
, pp. 1128-1133
-
-
Tekle, M.1
Bentinger, M.2
Nordman, T.3
Appelkvist, E.L.4
Chojnacki, T.5
Olsson, J.M.6
-
117
-
-
0028100832
-
Energy generation in parasitic helminths
-
Tielens AG. 1994. Energy generation in parasitic helminths. Parasitol Today 10:346-352.
-
(1994)
Parasitol Today
, vol.10
, pp. 346-352
-
-
Tielens, A.G.1
-
118
-
-
34248195476
-
Endogenous synthesis of coenzyme Q in eukaryotes
-
Tran UC, Clarke CF. 2007. Endogenous synthesis of coenzyme Q in eukaryotes. Mitochondrion 7 Suppl, S62-S71.
-
(2007)
Mitochondrion
, vol.7
, Issue.SUPPL.
-
-
Tran, U.C.1
Clarke, C.F.2
-
119
-
-
33745205101
-
Complementation of Saccharomyces cerevisiae coq7 mutants by mitochondrial targeting of the Escherichia coli UbiF polypeptide: Two functions of yeast Coq7 polypeptide in coenzyme Q biosynthesis
-
Tran UC, Marbois B, Gin P, Gulmezian M, Jonassen T, Clarke CF. 2006. Complementation of Saccharomyces cerevisiae coq7 mutants by mitochondrial targeting of the Escherichia coli UbiF polypeptide: two functions of yeast Coq7 polypeptide in coenzyme Q biosynthesis. J Biol Chem 281:16401-16409.
-
(2006)
J Biol Chem
, vol.281
, pp. 16401-16409
-
-
Tran, U.C.1
Marbois, B.2
Gin, P.3
Gulmezian, M.4
Jonassen, T.5
Clarke, C.F.6
-
121
-
-
0142150051
-
Mitochondrial formation of reactive oxygen species
-
Turrens JF. 2003. Mitochondrial formation of reactive oxygen species. J Physiol 552:335-344.
-
(2003)
J Physiol
, vol.552
, pp. 335-344
-
-
Turrens, J.F.1
-
123
-
-
0032886468
-
Conservation of the Caenorhabditis elegans timing gene clk-1 from yeast to human: A gene required for ubiquinone biosynthesis with potential implications for aging
-
Vajo Z, King LM, Jonassen T, Wilkin DJ, Ho N, Munnich A, Clarke CF, Francomano CA. 1999. Conservation of the Caenorhabditis elegans timing gene clk-1 from yeast to human: a gene required for ubiquinone biosynthesis with potential implications for aging. Mamm Genome 10:1000-1004.
-
(1999)
Mamm Genome
, vol.10
, pp. 1000-1004
-
-
Vajo, Z.1
King, L.M.2
Jonassen, T.3
Wilkin, D.J.4
Ho, N.5
Munnich, A.6
Clarke, C.F.7
Francomano, C.A.8
-
124
-
-
34147210988
-
Hydrogen peroxide sensing and signaling
-
Veal EA, Day AM, Morgan BA. 2007. Hydrogen peroxide sensing and signaling. Mol Cell 26:1-14.
-
(2007)
Mol Cell
, vol.26
, pp. 1-14
-
-
Veal, E.A.1
Day, A.M.2
Morgan, B.A.3
-
125
-
-
76249101651
-
Elevated mitochondrial reactive oxygen species generation affects the immune response via hypoxia-inducible factor-1alpha in long-lived Mclk1mouse mutants
-
Wang D, Malo D, Hekimi S. 2010. Elevated mitochondrial reactive oxygen species generation affects the immune response via hypoxia-inducible factor-1alpha in long-lived Mclk1mouse mutants. J Immunol 184:582-590.
-
(2010)
J Immunol
, vol.184
, pp. 582-590
-
-
Wang, D.1
Malo, D.2
Hekimi, S.3
-
126
-
-
58649090275
-
The anti-neurodegeneration drug clioquinol inhibits the aging-associated protein CLK-1
-
Wang Y, Branicky R, Stepanyan Z, Carroll M, Guimond MP, Hihi A, Hayes S, Mcbride K, Hekimi S. 2009. The anti-neurodegeneration drug clioquinol inhibits the aging-associated protein CLK-1. J Biol Chem 284:314-323.
-
(2009)
J Biol Chem
, vol.284
, pp. 314-323
-
-
Wang, Y.1
Branicky, R.2
Stepanyan, Z.3
Carroll, M.4
Guimond, M.P.5
Hihi, A.6
Hayes, S.7
McBride, K.8
Hekimi, S.9
-
127
-
-
84864024064
-
Sealing the mitochondrial respirasome
-
Winge DR. 2012. Sealing the mitochondrial respirasome. Mol Cell Biol 32:2647-2652.
-
(2012)
Mol Cell Biol
, vol.32
, pp. 2647-2652
-
-
Winge, D.R.1
-
128
-
-
0028950419
-
Mutations in the clk-1 gene of Caenorhabditis elegans affect developmental and behavioral timing
-
Wong A, Boutis P, Hekimi S. 1995. Mutations in the clk-1 gene of Caenorhabditis elegans affect developmental and behavioral timing. Genetics 139:1247-1259.
-
(1995)
Genetics
, vol.139
, pp. 1247-1259
-
-
Wong, A.1
Boutis, P.2
Hekimi, S.3
-
129
-
-
79953795039
-
Expression of the human atypical kinase ADCK3 rescues coenzyme Q biosynthesis and phosphorylation of Coq polypeptides in yeast coq8 mutants
-
Xie LX, Hsieh EJ, Watanabe S, Allan CM, Chen JY, Tran UC, Clarke CF. 2011. Expression of the human atypical kinase ADCK3 rescues coenzyme Q biosynthesis and phosphorylation of Coq polypeptides in yeast coq8 mutants. Biochim Biophys Acta 1811:348-360.
-
(2011)
Biochim Biophys Acta
, vol.1811
, pp. 348-360
-
-
Xie, L.X.1
Hsieh, E.J.2
Watanabe, S.3
Allan, C.M.4
Chen, J.Y.5
Tran, U.C.6
Clarke, C.F.7
-
130
-
-
84863624059
-
Over-expression of the Coq8 kinase in Saccharomyces cerevisiae coq null mutants allows for accumulation of diagnostic intermediates of the Coenzyme Q6 biosynthetic pathway
-
Xie LX, Ozeir M, Tang JY, Chen JY, Kieffer-Jaquinod S, Fontecave M, Clarke CF, Pierrel F. 2012. Over-expression of the Coq8 kinase in Saccharomyces cerevisiae coq null mutants allows for accumulation of diagnostic intermediates of the Coenzyme Q6 biosynthetic pathway. J Biol Chem 287:23571-23581.
-
(2012)
J Biol Chem
, vol.287
, pp. 23571-23581
-
-
Xie, L.X.1
Ozeir, M.2
Tang, J.Y.3
Chen, J.Y.4
Kieffer-Jaquinod, S.5
Fontecave, M.6
Clarke, C.F.7
Pierrel, F.8
-
131
-
-
78650455712
-
A mitochondrial superoxide signal triggers increased longevity in Caenorhabditis elegans
-
Yang W, Hekimi S. 2010. A mitochondrial superoxide signal triggers increased longevity in Caenorhabditis elegans. PLoS Biol 8:e1000556.
-
(2010)
PLoS Biol
, vol.8
-
-
Yang, W.1
Hekimi, S.2
-
132
-
-
67349139149
-
The effect of different ubiquinones on lifespan in Caenorhabditis elegans
-
Yang YY, Gangoiti JA, Sedensky MM, Morgan PG. 2009. The effect of different ubiquinones on lifespan in Caenorhabditis elegans. Mech Ageing Dev 130:370-376.
-
(2009)
Mech Ageing Dev
, vol.130
, pp. 370-376
-
-
Yang, Y.Y.1
Gangoiti, J.A.2
Sedensky, M.M.3
Morgan, P.G.4
-
133
-
-
79961209791
-
The role of DMQ(9) in the long-lived mutant clk-1
-
Yang YY, Vasta V, Hahn S, Gangoiti JA, Opheim E, Sedensky MM, Morgan PG. 2011. The role of DMQ(9) in the long-lived mutant clk-1. Mech Ageing Dev 132:331-339.
-
(2011)
Mech Ageing Dev
, vol.132
, pp. 331-339
-
-
Yang, Y.Y.1
Vasta, V.2
Hahn, S.3
Gangoiti, J.A.4
Opheim, E.5
Sedensky, M.M.6
Morgan, P.G.7
-
134
-
-
78049286776
-
Over-expression of COQ10 in Saccharomyces cerevisiae inhibits mitochondrial respiration
-
Zampol MA, Busso C, Gomes F, Ferreira-Junior JR, Tzagoloff A, Barros MH. 2010. Over-expression of COQ10 in Saccharomyces cerevisiae inhibits mitochondrial respiration. Biochem Biophys Res Commun 402:82-87.
-
(2010)
Biochem Biophys Res Commun
, vol.402
, pp. 82-87
-
-
Zampol, M.A.1
Busso, C.2
Gomes, F.3
Ferreira-Junior, J.R.4
Tzagoloff, A.5
Barros, M.H.6
-
135
-
-
84858004895
-
Parkinson's disease-like neuromuscular defects occur in prenyl diphosphate synthase subunit 2 (Pdss2) mutant mice
-
Ziegler CG, Peng M, Falk MJ, Polyak E, Tsika E, Ischiropoulos H, Bakalar D, Blendy JA, Gasser DL. 2011. Parkinson's disease-like neuromuscular defects occur in prenyl diphosphate synthase subunit 2 (Pdss2) mutant mice. Mitochondrion 12:248-257.
-
(2011)
Mitochondrion
, vol.12
, pp. 248-257
-
-
Ziegler, C.G.1
Peng, M.2
Falk, M.J.3
Polyak, E.4
Tsika, E.5
Ischiropoulos, H.6
Bakalar, D.7
Blendy, J.A.8
Gasser, D.L.9
|